Chapter 23:The Respiratory System - WordPress.com · Diseased/Disorders 1. Chronic obstructive...

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Chapter 23: The Respiratory System

Transcript of Chapter 23:The Respiratory System - WordPress.com · Diseased/Disorders 1. Chronic obstructive...

  • Chapter 23:

    The Respiratory

    System

  • Copyright 2009, John Wiley & Sons, Inc.

    Respiratory System Anatomy

    ■ Structurally

    ❑ Nose, pharynx and associated structures

    ❑ Larynx, trachea, bronchi and lungs

    ■ Functionally❑ conducts air to lungs

    ❑ Gas exchange

  • Copyright 2009, John Wiley & Sons, Inc.

    Respiratory System Anatomy

    ■3 anatomical regions

    ❑ Nasopharynx

    ❑ Oropharynx

    ❑ Laryngopharynx

  • Copyright 2009, John Wiley & Sons, Inc.

    Larynx

    ■Composed of cartilage❑ Thyroid cartilage or Adam’s apple

    ■Epiglottis - allows air to the trachea during breathing and food to the esophagus during swallowing.

  • Copyright 2009, John Wiley & Sons, Inc.

    Larynx

    ■Ventricular folds (false

    vocal cords) - Function

    in holding breath.

    ■Vocal folds (true

    vocal cords) - Vibrate

    and produce sound

    with air

  • Copyright 2009, John Wiley & Sons, Inc.

    Larynx

    ■Muscle

    contraction pulls

    vocal folds into

    airway

    ■Androgens

    make folds

    thicker and

    longer – slower

    vibration and

    lower pitch

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

    Trachea

    ❑ Extends from larynx■ Divides into right and

    left primary bronchi (leads to the lungs).

    ❑ C-shaped rings of hyaline cartilage■ Keeps trachea open

    (unlike the esophagus).

  • Copyright 2009, John Wiley & Sons, Inc.

    Location of Trachea

  • Copyright 2009, John Wiley & Sons, Inc.

    Lungs

    ❑ Right and left primary bronchus goes to lungs

    ❑ Mediastinum - tissue in between the lungs

    ❑ Pleural membrane -encloses each lung.

    ❑ Pleural fluid - aids in gas exchange

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

    Alveoli

    ❑ Very thin – only 0.5 µm thick to allow rapid diffusion of gases

    ❑ Pulmonary artery -deoxygenated blood

    ❑ Bronchial arteries –oxygenated blood to bronchi and bronchioles

  • Copyright 2009, John Wiley & Sons, Inc.

    Alveoli

    ❑ 2 types of alveolar cells

    ❑ Type I alveolar cells –most common, main site of gas exchange

    ❑ Type II alveolar cells (septal cells) – secrete alveolar fluid (aka surfactant)

  • Copyright 2009, John Wiley & Sons, Inc.

    Inhalation

    ❑Pressure inside alveoli lust become lower than atmospheric pressure for air to flow into lungs

    ❑Achieved by increasing the size of lungs

    ❑Inhalation – lungs must expand, increasing lung volume, decreasing pressure below atmospheric pressure

  • Copyright 2009, John Wiley & Sons, Inc.

    Inhalation

    ❑Inhalation is caused by contracting the diaphragm and the external intercostals. ❑Diaphragm – most

    important muscle of inhalation❑Responsible for 75% of

    air entering lungs during normal quiet breathing

  • Copyright 2009, John Wiley & Sons, Inc.

    Inhalation

    ❑External intercostals❑Contraction elevates

    ribs❑25% of air entering

    lungs during normal quiet breathing

  • Copyright 2009, John Wiley & Sons, Inc.

    Exhalation

    ❑Pressure in lungs greater

    than atmospheric pressure

    ❑Passive – muscle relax

    instead of contract

    ■ Diaphragm relaxes

    ■ External intercostals

    relax and ribs drop

    ❑Exhalation only active

    during forceful breathing

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

  • Copyright 2009, John Wiley & Sons, Inc.

    Oxygen Transport

    ❑1.5% of O2 is

    dissolved in plasma

    ❑98.5% bound to

    hemoglobin in red

    blood cells❑ Factors that affect

    O2 transport■ Acidity■ PCO2■ Temperature

  • Carbon Dioxide Transport

    ❑ 7% of CO2 is dissolved

    in blood.

    ❑ About 23% combines with

    hemoglobin

    ❑ 70% transported in

    plasma as HCO3-

    Carbon Dioxide + Carbonic Acid → Hydrogen Ions + Bicarbonate

    CO2 + H2CO3 → H+ + HCO3

    -

  • Diseased/Disorders

    1. Chronic obstructive

    pulmonary disease

    (COPD) (Both bronchitis

    and emphysema)

    2. Cystic Fibrosis

    3. Asthma

    4. Lung cancer

    5. Sudden Infant Death

    Syndrome (SIDS)

    6. Strep throat

    7. Diphtheria

    8. Influenza

    9. Pertussis (Whooping

    cough)

    10. Tuberculosis

    11. Pneumonia