Chapter 23:The Respiratory System - WordPress.com · Diseased/Disorders 1. Chronic obstructive...
Transcript of Chapter 23:The Respiratory System - WordPress.com · Diseased/Disorders 1. Chronic obstructive...
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Chapter 23:
The Respiratory
System
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Copyright 2009, John Wiley & Sons, Inc.
Respiratory System Anatomy
■ Structurally
❑ Nose, pharynx and associated structures
❑ Larynx, trachea, bronchi and lungs
■ Functionally❑ conducts air to lungs
❑ Gas exchange
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Copyright 2009, John Wiley & Sons, Inc.
Respiratory System Anatomy
■3 anatomical regions
❑ Nasopharynx
❑ Oropharynx
❑ Laryngopharynx
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Copyright 2009, John Wiley & Sons, Inc.
Larynx
■Composed of cartilage❑ Thyroid cartilage or Adam’s apple
■Epiglottis - allows air to the trachea during breathing and food to the esophagus during swallowing.
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Copyright 2009, John Wiley & Sons, Inc.
Larynx
■Ventricular folds (false
vocal cords) - Function
in holding breath.
■Vocal folds (true
vocal cords) - Vibrate
and produce sound
with air
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Copyright 2009, John Wiley & Sons, Inc.
Larynx
■Muscle
contraction pulls
vocal folds into
airway
■Androgens
make folds
thicker and
longer – slower
vibration and
lower pitch
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
Trachea
❑ Extends from larynx■ Divides into right and
left primary bronchi (leads to the lungs).
❑ C-shaped rings of hyaline cartilage■ Keeps trachea open
(unlike the esophagus).
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Copyright 2009, John Wiley & Sons, Inc.
Location of Trachea
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Copyright 2009, John Wiley & Sons, Inc.
Lungs
❑ Right and left primary bronchus goes to lungs
❑ Mediastinum - tissue in between the lungs
❑ Pleural membrane -encloses each lung.
❑ Pleural fluid - aids in gas exchange
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
Alveoli
❑ Very thin – only 0.5 µm thick to allow rapid diffusion of gases
❑ Pulmonary artery -deoxygenated blood
❑ Bronchial arteries –oxygenated blood to bronchi and bronchioles
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Copyright 2009, John Wiley & Sons, Inc.
Alveoli
❑ 2 types of alveolar cells
❑ Type I alveolar cells –most common, main site of gas exchange
❑ Type II alveolar cells (septal cells) – secrete alveolar fluid (aka surfactant)
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Copyright 2009, John Wiley & Sons, Inc.
Inhalation
❑Pressure inside alveoli lust become lower than atmospheric pressure for air to flow into lungs
❑Achieved by increasing the size of lungs
❑Inhalation – lungs must expand, increasing lung volume, decreasing pressure below atmospheric pressure
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Copyright 2009, John Wiley & Sons, Inc.
Inhalation
❑Inhalation is caused by contracting the diaphragm and the external intercostals. ❑Diaphragm – most
important muscle of inhalation❑Responsible for 75% of
air entering lungs during normal quiet breathing
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Copyright 2009, John Wiley & Sons, Inc.
Inhalation
❑External intercostals❑Contraction elevates
ribs❑25% of air entering
lungs during normal quiet breathing
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Copyright 2009, John Wiley & Sons, Inc.
Exhalation
❑Pressure in lungs greater
than atmospheric pressure
❑Passive – muscle relax
instead of contract
■ Diaphragm relaxes
■ External intercostals
relax and ribs drop
❑Exhalation only active
during forceful breathing
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
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Copyright 2009, John Wiley & Sons, Inc.
Oxygen Transport
❑1.5% of O2 is
dissolved in plasma
❑98.5% bound to
hemoglobin in red
blood cells❑ Factors that affect
O2 transport■ Acidity■ PCO2■ Temperature
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Carbon Dioxide Transport
❑ 7% of CO2 is dissolved
in blood.
❑ About 23% combines with
hemoglobin
❑ 70% transported in
plasma as HCO3-
Carbon Dioxide + Carbonic Acid → Hydrogen Ions + Bicarbonate
CO2 + H2CO3 → H+ + HCO3
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Diseased/Disorders
1. Chronic obstructive
pulmonary disease
(COPD) (Both bronchitis
and emphysema)
2. Cystic Fibrosis
3. Asthma
4. Lung cancer
5. Sudden Infant Death
Syndrome (SIDS)
6. Strep throat
7. Diphtheria
8. Influenza
9. Pertussis (Whooping
cough)
10. Tuberculosis
11. Pneumonia