Chapter 2 The Integumentary System. Integumentary System The body’s covering Includes: skin,...
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Transcript of Chapter 2 The Integumentary System. Integumentary System The body’s covering Includes: skin,...
Chapter 2
The Integumentary System
Integumentary System The body’s covering Includes: skin, nails, and hairs Skin: cutaneous membrane The skin (integument), is the largest organ of
the body covering over 7600 cm2 (3000 in2)
Structure Two main parts
Epidermis - surface epithelial layer Dermis - deeper connective tissue layer
Subcutaneous (subQ) layer or hypodermis lies deep to dermis; is not part of the skin
Integumentary System
Epidermis Keratinized stratified squamous epithelium Cell types (4):
Keratinocytes Melanocytes Langerhans cells Merkel cells
Epidermal Cells Keratinocytes
90% of epidermal cells 4-5 layers Produce keratin Protects skin Waterproofs skin
Epidermal Cells Melanocytes
Produce melanin that gives color to skin, hairs Transfer pigment to keratinocytes Make up 8% of epidermal cells
Epidermal Cells Langerhans cells
Immune response
Merkel cells Sense of touch Consist of tactile disc and neuron for touch sensation
Epidermal Layers Four Layers (strata)
Stratum basale Includes stem cells; new cells arise here
Stratum spinosum: 8-10 cell layer Cells beginning to look flattened
Stratum granulosum makes keratin Losing cell organelles and nuclei Have waterproofing lipid
Stratum corneum: flattened dead cells Cells here consist mostly of keratin. Cells here are shed and replaced from below.
Layers of the Epidermis
Dermis The dermis has several important
characteristics: is composed of connective tissue containing
collagen and elastic fibers contains two layers the outer papillary region consists of areolar
connective tissue containing thin collagen and elastic fibers, dermal papillae (including capillary loops), corpuscles of touch and free nerve endings
Dermis
The deeper reticular region consists of dense irregular connective tissue containing collagen and elastic fibers adipose cells, hair follicles, nerves, sebaceous (oil) glands, and sudoriferous (sweat) glands
Striae or stretch marks can appear if the skin is stretched too much
Dermis
Lines of cleavage - “tension lines” in the skin indicate the predominant direction of underlying collagen fibers
Epidermal ridges reflect contours of the underlying dermal papillae and form the basis for fingerprints (and footprints); their function is to increase firmness of grip by increasing friction.
Dermatoglyphics - the study of the pattern of epidermal ridges
Skin ColorNormal skin color is caused by the expression of a combination of i)
melanin, ii) carotene & iii) hemoglobin.Melanin – brown-black pigment produced in the melanocytes of the
stratum basaleAll races have virtually same # of melanocytes, but the amount of
melanin produced + degree of granular aggregation of the melanin determine whether an individual’s skin color is black, brown, tan or white
Melanin – protective device against UV damageGradual exposure to sunlight promotes the increased production of
melanin within the melanocytes – tanningAlbino – normal melanocytes but lacks the enzyme tyrosinase
(tyrosine melanin)Vitiligo – lacks of melanocytes in localized area – white spot
Albino vitiligo
Coloration of the Skin
Carotene – yellowish pigment found in epidermal cells and fatty parts of the dermis
Carotene is abundant is the skin of Asians + melanin – yellow-tan skin
Hemoglobin – not a pigment, oxygen-binding pigment found in RBC
Oxygenated blood flowing through the dermis gives the skin its pinkish tones
Accessory Structures Hair Skin glands Nails
Hair Found on most skin surfaces
Not on palmar surfaces of hand and fingers or plantar surfaces of feet
Made of fused keratinized cells
Consists of shaft and root Surrounded by hair follicle
Base is bulb which includes growing matrix producing cells
Nerves in hair root plexuses Muscle that pulls on hair: arrector pili
Causes hair to stand on end
Hair
Humans have three distinct kinds of hairLanugo is a fine, silky fetal hair that appears during
the last trimester of development. Not evident on a baby at birth unless it has been born prematurely.
Angora hair grows continuously in length, as on the scalp of males and females and on the face of males.
Definitive hair grows to a certain length and then ceases to grow. It is the most common type of hair. Eg. eyelashes, eyebrows, pubic & axillary hair.
Glands Sebaceous gland: secrete oily sebum
Connected to hair follicles; keeps hair from drying out
Sudoriferous (sweat) gland Eccrine sweat gland Wide distribution – thermoregulation Apocrine sweat gland Axilla, groin, areolae, beard Contain other cell material
Ceruminous (wax) gland Wax combines with sebum to produce earwax
Nails Plates of packed hard
dead keratinized cells Nail body: major visible
portion Free edge: part
extending past finger or toe
Root: cells deep to here (in nail matrix) form new nail cells
Nails
Functions of Skin Temperature regulation Protection Sensory reception Excretion and absorption: small amounts Vitamin D synthesis
Thermoregulation
Body temperature tends to increase as a result of exercise, fever, or an increase in environmental temperature.
Homeostasis is maintained by the loss of excess heat. The blood vessels (arterioles) in the dermis dilate and allow
more blood to flow through the skin, thus transferring heat from deeper tissues to the skin.
To counteract environmental heat gain or to get rid of excess heat produced by the body, sweat is produced.
The sweat spreads over the surface of the skin, and as it evaporates, heat is lost from the body.
Thermoregulation
If body temperature drops below normal, heat can be conserved by a decrease in the diameter of dermal blood vessels, thus reducing blood flow to the skin.
With less warm blood flowing through the skin, however, the skin temperature decreases.
If the skin temperature drops below approximately 15 degrees Celsius, blood vessels constrict, which helps to prevent tissue damage from the cold.
Contraction of the arrector pili muscles causes hair to stand on end, but with the sparse amount of hair covering the body, this does not significantly reduce heat loss in humans.
Hair on the head, however, is an effective insulator.
Aging Adolescence: can develop acne Most effects in dermis, with visible signs
of aging by about age 40. These include: Loss of collagen fibers Loss of elasticity Loss of immune responses Decreased melanocyte functions:
gray hair, skin blotches Thinning of skin and hairs
Anti-aging treatments
Conditions of the skin & associated structures indicating nutritional deficiencies or body dysfunctions
Condition Deficiency CommentsGeneral dermatitis Zinc Redness & itching
Scrotal or vulva dermatitis
Riboflavin Inflammation in genital region
Hyperpigmentation B12, folic acid, or starvation
Dark pigmentation on backs of hands & feet
Dry, stiff, brittle hair Protein, kcal, & other nutrients
Usually occurs in young children or infants
Follicular hyperkeratosis
Vit A, unsaturated fatty acids
Rough skin due to keratotic plugs from hair follicles
Pellagrous dermatitis Niacin & tryptophan Lesions on areas exposed to sun
Thickened skin at pressure point
Niacin Noted at belt area at the hips
Spoon nails Iron Thin nails that are concave of spoon-shaped
Dry skin H20 or thyroid hormone Dehydration, hypothyroidism, rough skin
Oily skin (acne) Hyperactivity of sebaceous glands
Spoon nail
Additional Info: Sun Safety Tips Watch the clock
Avoid exposure from 10AM – 4PM Sunblock SPF 15 or 30 if at high risk
UVA/UVB Apply 30min before exposure Reapply every 2hrs
Wear sunglasses & protective clothing Do not prolong sun exposure just because
you are wearing sunscreen!
Copyright 2010, John Wiley & Sons, Inc.