Ch 42 Circulation

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    Plasma-55%

    Formed

    elements-45%

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    Circulatory system

    Closed circulatory system

    Open circulatory system

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    Open Circulatory System

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    Human circulatory system

    closed and complete doubled circulatory system

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    Blood vessels

    Artery

    Vein

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    Artery

    vein

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    ArteryVein

    Valve

    endothelium

    Smooth muscles

    Connectivetissue

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    Artery/Vein differences

    Arteries Veins

    Direction

    of flow

    Carry oxygenate

    blood Away from

    Heart

    Carry deoxygenated

    blood to Heart

    Pressure Higher Lower

    Walls THICKER muscular

    wall

    THINNER musculat

    wallLumen Smaller Larger

    Valves No valves Valves (see next)

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    Vertebrate Heart 4-Chambered heart

    atria (atrium)

    thin wall

    collection chamber

    receive blood

    ventricles

    thick wall pump

    pump blood outright

    atrium

    leftatrium

    right

    ventricle

    left

    ventricle

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    Electrical signals

    allows atria to emptycompletely beforeventricles contract

    stimulates ventriclesto contract from

    bottom to top, drivingblood into arteries

    heart pumping controlled by electrical impulses

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    One-Way Valves in

    Veins

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    Sphygnomamometer

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    Measuring Blood Pressure

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    Capillaries

    capillary vessel

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    venule capillaries

    arteriole

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    AtriumVentricle

    http://www.gsu.edu/~bioasx/fish.gifhttp://www.gsu.edu/~bioasx/fish.gifhttp://www.meer.org/fishbody-teeth-gills-2a.gif
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    Countercurrent exchangesystem

    Fig. 42-21b

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    g

    Gills

    (b) Crayfish

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    A BLOOD CLOT

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    THE HEMOSTASIS PROCESSES

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    arteriole

    venule

    lymphaticcapillaries

    bloodcapillaries

    lymphatic

    vessel

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    Lymph

    Water plus solutes from two sources

    Plasma: ions, nutrients, gases, some proteins

    Cells: hormones, enzymes, waste products

    Returns to circulatory system via veins;

    essential for fluid balance.

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    Formation of Lymph

    interstitial fluid

    blood capillary

    lymphatic capillary

    tissue cell

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    Components of the Lymphatic

    SystemA. Lymphfluid collected in lymph vessels

    Clear straw colored fluidsame basic

    component as plasma

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    Function

    1. Collects fluid lost from the blood and returns

    it to the circulatory system

    More than three liters of fluid leave the capillarieseach day

    This continually bathes the cells

    There is twice as much lymph in the body as blood

    Lymph is dumped back into the circulatory system

    thru the superior vena cava

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    Functions contd

    2. Filters fluid to rid it of bacteria and other

    pathogens

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    More Functions

    3. Collects fat from the small intestine and

    delivers it to the circulatory system

    4. Generates and stores WBCs called

    lymphocytes that fight infection

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    How is fluid moved?

    Contraction of skeletal muscles againstlymphatic vessels

    Smooth muscle contraction

    Valves in lymphatic vessels

    Breathing

    Obstruction of system leads to edema

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    Edema

    Swelling of tissues due to excess fluid

    accumulation

    Caused by disease or injury

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    Lymph Transport

    lacks pump for circulation relies on activity of skeletal muscles and

    pulsation of nearby arteries for movement of

    fluid

    3L of lymph enters blood stream every 24 hrs proteins easily enter lymphatic system

    uptake of large particles such as cell debris,

    pathogens, and cancer cells

    lymph nodes where it is cleansed of debris

    and examined by cells of the immune system

    (WBC)

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    The Body Has Three Lines of

    Defense Physical and Chemical Barriers

    Nonspecific Defenses

    Specific Defense Mechanisms

    Ph i l d Ch i l B i

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    Physical and Chemical Barriers

    Table 9.1

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    Physical and chemical barriers

    Skin: characteristics of barrier

    Structure: dead layer, inhospitable to microorganisms

    Constant replacement: many adhering microorganisms

    removed

    pH = 5-6: too acidic for many microorganisms

    Other: tears, saliva, earwax, digestive acids, mucus,

    vomiting, urination, defecation, resident bacteria

    (normal flora)

    First Line of Defense: Skin

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    Nonspecific Defenses : 2nd Line

    Neutrophils and

    Macrophages engulf and

    digest foreign cells.

    Eosinophils bombard large

    parasites with digestive

    proteins and phagotyze

    foreign proteins.

    These are all white bloodcells.

    Why are they nonspecific?

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    Neutrophils

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    Macrophage attacking e-coli.

    http://www.med.sc.edu:85/ghaffar/macrophage-ecoli2.jpghttp://www.med.sc.edu:85/ghaffar/macrophage-ecoli2.jpghttp://www.med.sc.edu:85/ghaffar/macrophage-ecoli2.jpghttp://www.med.sc.edu:85/ghaffar/macrophage-ecoli2.jpg
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    Figure 8-12