Activity 2

Cells and Disease

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

How do observations of cells help doctors and scientists diagnose and study diseases?

EQ

Activity 2: Cells and Disease

Get Started

Where do you think cells are involved in life processes?

Why do you think scientists and doctors study cells?

Activity 2: Cells and Disease

Introduction

A disease is any breakdown in the structure or function of an organism.

Microbe is a microscopic cellular organism or virus.

Read the introduction pg 161.

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

Using a Microscope

Activity 2: Cells and Disease

Procedure

Read the patient histories and table of possible diseases before you get your microscope slides.

Compare each patient’s blood sample to the typical blood sample.

Part B: Observing Blood

Activity 2: Cells and Disease

Procedure

Procedure Steps 4,5, and 9 (1 Stamp)

Analysis Questions 1-6 (1 Stamp)

Case Study Malaria (1 Stamp)

Stamp Checks

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

Observations of Blood Samples

Slide Shape of Cells Color of Cells Number of cells in field of view

Typical Human Blood

Patient A

Patient B

Prepare the chart below in your journal

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

Patient A

Blood Samples (Stamps at 5, 8, 9, AQ)

Patient B

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

Activity 2: Cells and Disease

Follow Up

What diagnosis did you give to Patient A, and what was your evidence?

What diagnosis did you give Patient B, and why?

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

Observe the diagrams below. Which patient would you diagnose with sickle cell disease? Explain, using evidence from this activity.

Analysis 3

Patient 1 Patient 2

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

Based on the diagrams, how does the shape of normal red blood cells help them perform their function? How does the shape of sickled red blood cells prevent them from performing their function?

Activity 2: Cells and Disease

Follow Up

How do microscope observations of cells help doctors and scientists diagnose and study diseases? Give specific examples from this activity.

Analysis 4

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

From what you learned about malaria in the case study:◦A trade-off is an exchange of one thing in return for

another, giving up something that is a benefit or advantage, in exchange for something that may be more desirable. What are the trade-offs of using insecticides to kill the mosquitoes?

◦What are the benefits of using insecticides to kill mosquitoes that might be carrying Plasmodium?

Analysis 5

Activity 2: Cells and DiseaseActivity 2: Cells and Disease

How do observations of cells help doctors and scientists diagnose and study diseases?

Revisit the Challenge

Activity 2: Cells and Disease

Key Vocabulary

cell disease infectious disease malaria microbe mutation noninfectious disease protein

protist sickle cell trade-off vector

Key Vocabulary