Cell Biology 2011 Spring
63
Figure 13-3 Molecular Biology of the Cell (© Garland Science 2008) Intracellular Vesicular Traffic
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Biologie celulara
Transcript of Cell Biology 2011 Spring
Figure 13-3 Molecular Biology of the Cell (© Garland Science 2008)
Intracellular Vesicular Traffic
Figure 13-1 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-2 Molecular Biology of the Cell (© Garland Science 2008)
The Molecular Mechanisms of Membrane Transport and the
Maintenance of Compartmental Diversity
There Are Various Types of Coated Vesicles
Figure 13-5 Molecular Biology of the Cell (© Garland Science 2008)
The Assembly of a Clathrin Coat Drives Vesicle Formation
Figure 13-7a, b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-7c, d Molecular Biology of the Cell (© Garland Science 2008)
Both The Pinching-off and Uncoating of Coated Vesicles Are
Regulated Processes
A current model of COPII-coated vesicle formation
Monomeric GTPases Control Coat Assembly
SNARE Proteins and Targeting GTPases Guide Membrane
Transport
The postulated role of SNAREs in guiding vesicular transport
The structure of paired SNAREs
Interacting SNAREs Need To Be Pried Apart Before They
Can Function Again
Dissociation of SNARE pairs by NSF after a membrane fusion cycle is
completed
Rab Proteins Help Ensure the Specificity of Vesicle Docking
A postulated role of Rab proteins in facilitating the docking of transport vesicles
Table 13-1 Molecular Biology of the Cell (© Garland Science 2008)
Rab Proteins Help Ensure the Specificity of Vesicle Docking
Figure 13-19a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-19b Molecular Biology of the Cell (© Garland Science 2008)
Transport from the ER through the Golgi
Apparatus
Proteins Leave the ER in COPII-coated Transport Vesicles
Only Proteins That Are Properly Folded and Assembled Can
Leave the ER
Transport from the ER to the Golgi Apparatus Is Mediated
by Vesicular Tubular Clusters
Homotypic membrane fusion
Vesicular tubular clusters
The Retrieval Pathway to the ER Uses Sorting Signals
A model for the retrieval of ER resident proteins
Two possible models explaining the organization of the Golgi apparatus
and the transport of proteins from one cisterna to the next
Transport from the Trans Golgi Network to Lysosomes
Figure 13-37 Molecular Biology of the Cell (© Garland Science 2008)
Lysosomes Are Heterogeneous
Figure 13-38 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-39 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-41 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-42 Molecular Biology of the Cell (© Garland Science 2008)
Multiple Pathways Deliver Materials to Lysosomes
Figure 13-42a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-42b Molecular Biology of the Cell (© Garland Science 2008)
A Mannose 6-Phosphate Receptor Recognizes Lysosomal
Proteins in the TransGolgi Network
Figure 13-44 Molecular Biology of the Cell (© Garland Science 2008)
The transport of newly synthesized lysosomal hydrolases to lysosomes
Figure 13-45 Molecular Biology of the Cell (© Garland Science 2008)
The recognition of a lysosomal hydrolase
Page 799 Molecular Biology of the Cell (© Garland Science 2008)
Transport from the TransGolgi Network to the Cell
Exterior: Exocytosis
Figure 13-63 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-64 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-65a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-65b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-66a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-66b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-71 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-72 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-72a Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-72b Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-73 Molecular Biology of the Cell (© Garland Science 2008)
Figure 13-74 Molecular Biology of the Cell (© Garland Science 2008)
Page 721 Molecular Biology of the Cell (© Garland Science 2008)
Figure 12-30 Molecular Biology of the Cell (© Garland Science 2008)
Figure 12-32a Molecular Biology of the Cell (© Garland Science 2008)
Figure 12-32b Molecular Biology of the Cell (© Garland Science 2008)
Figure 12-33 Molecular Biology of the Cell (© Garland Science 2008)
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