Commited by nature for more 30 years

CDMO

Quality and agility in the service of our CDMO* clients

COMMITTED BY NATURE

Véto-pharma – Development and Manufacturing is positioned purely as a CDMO within the vete-rinary and food supplement industry, offering value-added services for 30 years. Research tax credit certified since 2014.

*Contract Development and Manufacturing Organization

Visitors entrance

Reception

WarehouseShipping

Shipping

Receiving & Sampling

Production

ProductionAdministrative

R&D QCProduction

Warehouse

Administrative

Plant: 10.000m2

Production areas:3.000m2

Laboratories: 300m2

Warehouse storage:3.300m2

While retaining the agility of a small organisation with around 60 employees, at Véto-pharma – Development and Manufacturing we receive the support of our parent company UPL Group, enabling us to invest in and drive many projects in the service of our clients.

More than a standard CMO, our bespoke CDMO services enable us to support our clients in a large number of projects.

Remains 100% dedicated to its clients.

Creation of the Wyjolab laboratory by two French chemical engineers.

Wyjolab joined the Arysta LifeScience Group and has since enjoyed the skills and resources that come with being a part of a multinatio-nal group. The active support of our parent company, together with the continuous development of our expertise and production methods, have enabled us to offer services to our clients that respond ever more closely to the requirements and developments of the animal health market.

Continued expansion of the produc-tion site, now offering a surface area of 10,000m2, with the construction of a new logistics building, com-prising a fully ergonomic sampling booth, in line with GMP standards, and new storage facilities.

Administrative merger of Wyjolab with Véto-pharma – Beekeeping, its sister company, and the pooling of expertise to make their stronger in the face of global competition. The old adage “strength in num-bers” makes good sense. Within a single enterprise, its employees will join forces, creating new opportu-nities for growth and performance, combined with the desire to meet its clients’ ever-higher expectations in terms of quality.

New state-of-the-art production unit dedicated to the drug polymers extruded.

New GMP liquid and semi-liquid production unit.

New fully GMP powder produc-tion unit and two new quality control and development labo-ratories. This major restructuring of the site at Chaillac (36) gave us the opportunity to respond even more closely to the developments of animal health market.

Wyjolab celebrated its 30-year anniversary. This event provided the opportunity to shine a spot-light on those who have been involved for many years in this human adventure. This anniver-sary heralded new challenges to be met and a new organisational design…

1988

2002

2012

2018

1994

2005

2015

2019

FROM WYJOLAB TO VÉTO-PHARMA

OUR MISSION

To support all our clients by:

• Creating quickly and differentlyYou provide a new vision of the issues at the heart of each of your projects. Our teams work together with your dedicated departments to help find the best solutions for your markets through a consultancy approach.

• Implementing a saving strategyYou save time in terms of production, control and development, while optimising your pro-duction capacities, transferring the investments linked to the upkeep of GMP infrastructures to our specialist organisation and increasing flexi-bility.

• Focusing you on your core businessBy freeing up your time and resources dedi-cated to non-core activities, you can enhance your expertise in your most strategic products and well-established technologies, making you more effective in serving your clients.

OUR VISION & MISSION

At Véto-pharma, we draw daily on the values that form an integral part of our business. These values help stimulate our development strategy and guide our future decisions.

OUR COMMITMENTS

Quality• Production on a EU-GMP site with pharma-ceutical-level surveillance, irrespective of the regulatory status of your product types.

• The right human and material resources to guarantee a high level of quality for your pro-ducts.

Flexibility• Batch sizes tailored to each market (from 200L for the smallest offers).

• Optimisation of formulae and packaging gua-ranteed for all your projects.

Spirit of service• Response to all quotation requests within two weeks (except in case of distinctive features requiring a longer period).

• Contractual commitment to delivery times and annual review of all current projects.

• Non-competition guarantee with your products.

• Confidentiality for all your projects.

OUR VALUES• Committed to our customers• Creative• High-performance• Involved• Respectful of mankind and nature

Formulation and Industrial transfer

OUR DEVELOPMENT OFFERS

Medicines* Hygiene and treatment productsFood supplements

Véto-pharma – Development and Manufacturing is making its development laboratory available, offering you an optimal solution for updating an existing product and relaunching it on an often competitive animal health market or providing your clients with an innovative solution.

• PROACTIVE DEVELOPMENT Aimed at our group for minor species or for the licensing of products indicated for the treatment of major species.

• Liquid: emulsion, solution, suspension• Semi-liquid: Gel, paste, cream, ointment, ...• Powder: mixing, direct com-pression, micro-granulation by sizing - Tablet• Extruded forms: drug polymers, collars, soft chews, ...

• AD HOC DEVELOPMENTBased on the specifications of our clients (substitution of a raw material, adjustment of a formula and/or manufacturing process, etc).

Joint drafting of the development �specifications

Supplier and raw materials specifications�evaluation

Packaging adaptation

Pre-formulation, formulation, excipient and preservative justification

Analytical validation

Drafting of the indus-trial�specifications�and�feasibility batches

Adaptation and regulatory batches

A BESPOKE DEVELOPMENT PROCESS

Extrusion machine

*non

-injec

tabl

e, cy

toto

xic a

nd ß

-lact

am.

CONSULTANCY ON AND COMPLETION OF SPECIFIC STABILITY STUDY PROTOCOLS:

• Pre-stability for formula selection,• Stability in long-term, intermediate and accelerated conditions,• Stability after opening and in use,• Ongoing stability,• Container / content interaction.

Our GMP laboratory is equipped to carry out stability studies as part of your development projects or as post-marketing surveillance. Véto-pharma – Development and Manufacturing offers a large storage capacity within climatic chambers under ICH conditions for initial (real or accelerated time) or ongoing stability.

STABILITY STUDIES

Temperature (°C) Moisture % 25 60 30 65 40 75

Storage under VICH conditions, surveillance 24 hours a day 7 days a week, in line with pharmaceutical requirements.

Analytical development and stability studies

OUR TEAMS OFFER A BESPOKE SERVICE

• Comprehensive development of an analysis method to quantify a compound contained in an finished product.

• Adaptation of an existing method in case of product reformulation (change of form, excipients or industrial manufacturing process).

• Completion of product analyses during development (formulation) to verify the stability of the product over time.

STORAGE AND MANAGEMENT OF YOUR SAMPLES

We have the ability to produce a wide range of dosage forms including:

MANUFACTURING LIQUID AND SEMI-LIQUID FORMS

GMP-compliant Non-sterile manufacturing product

YOUR BENEFITS

• Materials supplied in accordance with your spe-cifications and standards,

• Flexible batch sizes ran-ging from 150L to 3.000L for liquid forms,

• Complete traceability and high qual ity standards for all products, including non-pharmaceutical forms.

LIQUID Emulsion, solution and suspension aqueous and oily

SEMI-LIQUIDGel, cream, paste, ointment, ...

Olsa mixer

BULK MANUFACTURINGMixers: from 150L to 3.000L

A whole range of packaging alterna-tives suited to each application

IMMEDIATE PACKAGING

BIG PACKAGINGFlasks from 5L to 200L Semi-automatic filling

Semi-liquid line “Kalix“

Liquid line “Stoppil“

LIQUID AND SEMI-LIQUID PACKAGINGFrom 3mL to 200L

GMP-compliant Small, medium and large batch sizes

SMALL PACKAGING LINES

• Solution, suspension, emulsion and low viscosity gelAll flasks types from 50mL to 5L

• Paste and creamCartons, pots and oral applicators from 3mL to 60mL

YOUR BENEFITS

• Custom packaging for individual or bulk quan-tities designed to deliver the correct dosages and maximize shelf life.

• Design and production of printed materials and secondary packaging (dis-play racks, cabinets, point-of-purchase units).

SECONDARY PACKAGING

Our services until forwarding

Packaging

Heat sealing

Labeling

Packaging

FROM HEAT-SEALING TO PALLETIZING

Heat sealing

OUR PACKAGING FACILITIES

Thermic transfer coding.Inscription of mobile mentions.

Labeling

Multi-format cartoning machines.Inserting notices, accessories, ...

BundlingBulking, case packing, display box packaging, blister, shrink-wrapping, ...

Shipment

Flexibility of packaging sizes

Flexibility of batches sizes

MANUFACTURING POWDER FORMS

BULK MANUFACTURINGMixers: from 200L to 3.000L WAM horizontal powder ploughshare mixer Capacity 3.000L, equipped with «Lodige» type coulter with spray system and an impregnation device.

CMS rotary drum mixerFlexible in terms of batch from 200L to 2.000L.Slow system with a sieving emerger and containers carrying out rotary mixture.

POWDER More or less worked by cold processes of compacting or sizing. Semoulette, micro-granule, ...

TABLETUp to 25mm in diameter

CMS mixer

WAM mixer

GMP-compliant Non-sterile manufacturing

YOUR BENEFITS

• Materials supplied in accordance with your spe-cifications and standards,

• Flexible batch sizes ran-ging from 100kg to 2T,

• Complete traceability and high qual ity standards for all products, including non-pharmaceutical forms.

IMMEDIATE AND OUTER PACKAGING

BIG PACKAGING LINES Containers, big bags, bags and buckets 20/25kg.

SMALL PACKAGING LINESFlasks, pots, pill boxes, sachets, doypacks, etc. In various sizes.Single-dose sachet 1mL to 15mL.

Manufacturing up to 25mm in diameter

Manufacturing up to 50mm in diameter

ROTARY FETTE P2000 LINE

KORSCH EK2

Rotary tablet press machine supplied directly by powder containers.

Press alternative machine

TABLETS PRESS

BOLUS PRESS

OUTER PACKAGING

• Lines: Heat sealing, thermal transfer coding,

labelling, multi-format cartoning machine, bulking, case packing, display box packaging, blister, shrink-wrapping,

etc.

including drug polymers, collars, soft chews,...

We can also expand our current capabilities by creating partnerships that integrate new technologies and equipment dedicated to your specific needs as the market develops, in line with regulatory requirements.

EXTRUDED FORMS

UNIDOSE STICK PACK LINE

The single-dose stick pack already dominates the market for individual servings in the food industries and constantly grows in the pharmaceutical field.

UNIDOSE PACKAGING

Liquid and paste from 1mL to 10mL

Control Quality process

QUALITY CONTROLLABORATORY

From the receipt of raw materials to the release of finished products

Control at the receipt: Raw materials, packaging material, labels

Finished product control

Samples library

Metrology

Stability studies of finished products and pharmaceutical raw materials

Production monitoring: Sample control on bulk products

3 POLES OF MATERIAL ANALYSIS

• Small benchtop equipment: potentio-meter, polarimeter, melting point appa-ratus, pH meter, conductivity meter, ...

• Hot pole: furnace, gas chromato-graphs for the determination of active ingredients, quantification of impurities in these same active ingredients and finished products.

• Cold pole:- 3 HPLC machines for the quantifica-tion of active ingredients in a finished product or a search for impurities in an active ingredient or another compound.- UV spectrophotometer for the charac-terization of raw materials and dosages as well.- 2 infrared devices used for the charac-terization of raw materials.

Our laboratory offers on-demand services and is also capable of conducting significant analysis projects, including physicochemical analysis, identification and dosage.

CDMO

vetopharma-cdmo.com

ZA de Champrue 36310 Chaillac • France

Email : info@vetopharma.com Tel : +33 (0)2 54 25 61 32 Fax : +33 (0)2 54 25 67 21

www.vetopharma-cdmo.com linkedin.com/company/vetopharma-cdmo

Come to meet us and visit the plant!

VPH

DF-

V1-0

4-20

19 ©

pho

to c

redi

t - V

éto-

phar

ma