Causes of Inferlity in WomenCauses of Infertility in Women

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    Inability to conceive despite tryinghaving regular intercourse forone ye

    causes could be due to female fac

    male factors

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    Causes InWomen

    Cervical

    Tubal

    Uterine

    Ovarian

    Endometriosis

    Unexplained

    Age

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    Laser conization- low secre

    Anti-Sp

    Blockage of the vagina

    Imperforate hymen

    Extremely narrow vagina

    Painful infections in the vagina

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    Uterine Causes

    Infertility inWomenCongenital

    Asherman Syndrome

    Fibroids

    Fibrosis

    Endometrial Polyps

    Adenomyosis

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    Treatment:

    Hysteroscopic resection o

    adhesions can be done bu

    need multiple sessions, in

    to giving steroids with est

    three weeks after surgery

    recurrence.

    Asherman Syndrome:

    Intra uterine adhesion

    (srepeated curettage, severe

    endometritis, scars of uterine

    surgery). Decreased amount of blood

    loss during menstruation.

    Can be diagnosed easily using

    hysterosalpingogram.

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    Fibroids:

    Benign uterine tumor .

    Adenomyosis They usually do not causeinfertility unless it affects the intrauterine cavity in

    an obvious way, but if no other reason for infertility

    can be found, it is better to do myomectomy

    (excision of the fibroid ) and restore the

    intrauterine cavity.

    Myomectomy can be done either by Hysteroscopic

    resection or by laparotomy

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    Endometrial polyp: Its presence mimics IUCD, polyps can be diagnosed

    ultrasound or hysteroscopy then polypectomy (removing the polyp) can

    easily.

    Adenomyosis: Symptoms include secondary dysmenorrhea, some horm

    treatments could be helpful e.g. GNRH analogues, or Danazol, the decis

    treatment should be taken by the treating physician.

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    Chronic Pelvic

    Infections

    Fimbral End

    Destruction

    Adhesions

    Short tub

    Tubal Tumors

    Tubal Cause Of Infertility

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    Chronic Pelvic Infections:

    Cause tubal congestion.

    Obstruction (>3cm ) results in impeding of the oocyte

    transfer, May result in pelvic adhesions that will affect tubal

    movement.

    Slowing it so inappropriate time for oocyte transfer interferes

    with fertilization.

    Tubal occlusion or pelvic adhesions that cause inability for

    the fimbrial ends to catch the oocyte from the ovary or as

    mentioned before abnormal movement of the tubes and

    oocyte transfer. Causes for PID include infections with E.coli, or Gonococcus

    infection (STD) PID affects ovarian function and tubal

    movement

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    Destruction of the fimbrial ends : Disabling its function

    in catching oocytes into the tubes, PID or endometriosis

    can cause this.Adhesions: Caused by tubal surgery done for ectopic

    pregnancy, pelvic surgery done to the tubes or due to

    appendicitis.

    Tubal Tumors affecting it's function.

    Short tubes (less than 4cm).

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    Polycystic Diseases

    Functional Failure

    Pituitary Failure

    Endocrino

    Hypothalamic Fa

    Ovarian Dysfunction

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    Polycystic ovarian disease:

    have what is called polycys

    involves having follicles con

    than the normal condition.

    woman has normal fertili

    associated with some condit

    polycystic ovarian syndro

    pathological.

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    Women with e tubal occlusion

    Male abnormal semen analysis

    Women with PCOD will need IVF, should be individualized

    Treatment of hormonal imbalance is the best thing

    Recurrent abortions in PCO:

    Increased LH level

    Control before starting induction of ovulation.

    Ovarian diathermy lowers LH

    lower recurrent miscarriages w

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    Congenital: Genetic and chromosomal causes

    Ovarian agenesis. Hereditary causes for accelerated loss of ovarian

    reserve.

    Familial premature ovarian failure.

    Chromosomal abnormalities (47XXX).

    Exposure to certain factors:

    Large amount of radiation exposure.

    Chemotherapeutic agents as in cancer

    treatment.

    Viruses such as mumps.

    Heavy smoking.

    Congenital : enzymatic dy

    17- Hydroxylase Defici

    Galactosemia.

    Extras :

    Autoimmune causes: Preantibodies.

    Lack of (or dysfunction)

    ovarian receptors.

    Idiopathic causes.

    Surgical oopherectomy.

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    Secondary disorder of Gonadotro

    Regulation:

    1. High prolactine level

    2. Pituitary adenoma

    3. Idiopathic hypothyroidism

    4. side effect to medication

    5. Suprapituitary Tumors

    6. Pituitary Tumors, trauma such

    7. Radiation exposure to the pitu

    8. Idiopathic causes.

    LH and FSH gonadotrophin Defici

    1. Pituitary tumors.

    2. Destructive pituitary lesion.

    3. Pituitary ablation.

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    Causes :

    Rapid and sudden increase or decrease

    weight.Severe psychological and neurological st

    strenuous exercises.

    Radiation exposure.

    Medications that cause hypothalamic fa

    Tumors.

    Unknown causes.

    Endocrinopathy

    Adrenal gland dysfunction

    Thyroid gland problems.

    Hypothyrodism

    Pancreatic problems ww

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    "Endometriosis Is Presence of Endometrial Tissues Outside Endom

    Affects pregnancy either by forming chocolate cyst

    (endometrioma) or by causing adhesions.

    Diagnos -Laparoscopy

    Treatment:

    Laparoscopic adhesiolysis,

    Cauterization of endometriotic spots,

    Salpingostomy and reanastomosis of fallopian tube problems.

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    Hypotheses

    Stress and worries changes in internal hormones ,decre

    secretions or muscular spasm, including those lining fallopian

    its obstruction, or muscles lining the vagina causing dyspareun

    Stress also has its effects on the hypothalamus and ovarian fu

    Couple seeking pregnancy to try, as much as possible, to allevia

    worries and have trust in god and trust their treating ph

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