Care of the treatment experienced patient who failed prior hcv therapy

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Care of the Treatment- experienced Patient With HCV Infection Who Failed Prior Therapy

description

Care of the Treatment-experienced Patient Who Failed Prior HCV Therapy

Transcript of Care of the treatment experienced patient who failed prior hcv therapy

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Care of the Treatment-experienced Patient With HCV

Infection Who Failed Prior Therapy

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Case53-year-old Black Man

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Case (cont)

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Case (cont)

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Case (cont)

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Second Treatment Regimen

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Case (cont)

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Why Is Achieving SVR So Important?

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Why Is Achieving SVR So Important?

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Potential Treatment Options for the Case Patient

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Simeprevir for Treatment-naive Patients

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Simeprevir for Treatment-experienced Patients

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Sofosbuvir

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COSMOSOff-Label Combination of Sofosbuvir and Simeprevir RBV in

Patients With G1 HCV Infection

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SAPPHIRE-I and SAPPHIRE-II ABT-450/r (protease inhibitor and ritonavir) + ABT-

267 (NS5A inhibitor) + ABT-333 (non-nucleoside polymerase inhibitor) × 12 weeks

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LONESTAR Trial Sofosbuvir and Ledipasvir Fixed-Dose

Combination RBV

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Abbreviations

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References

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References (cont)