Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal...

9
1 ECG (Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ARL-EL4703-Instrumentasi Biomedis 3 Cardiac Conduction System (2) ARL-EL4703-Instrumentasi Biomedis 4 The ECG (1) ARL-EL4703-Instrumentasi Biomedis 5 The ECG (1) ARL-EL4703-Instrumentasi Biomedis 6 The ECG (1) Electrocardiography 1. Standard clinical ECG (12 leads) 2. VCG (3 orthogonal leads) 3. Monitoring ECG (1 or 2 leads)

Transcript of Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal...

Page 1: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

1

ECG(Electrocardiogram)

Achmad RizalBioSPIN

ARL-EL4703-Instrumentasi Biomedis 2

Cardiac Conduction System (1)

ARL-EL4703-Instrumentasi Biomedis 3

Cardiac Conduction System (2)

ARL-EL4703-Instrumentasi Biomedis 4

The ECG (1)

ARL-EL4703-Instrumentasi Biomedis 5

The ECG (1)

ARL-EL4703-Instrumentasi Biomedis 6

The ECG (1)Electrocardiography1. Standard clinical ECG (12 leads)2. VCG (3 orthogonal leads)3. Monitoring ECG (1 or 2 leads)

Page 2: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

2

ARL-EL4703-Instrumentasi Biomedis 7

Modern ECG

Figures above show how the earliest ECGs were recorded by Einthoven at 1900.Vats of salt water provided the electrical connection to the body. The string galvanometer served as the measurement instrument for recording the ECG. ARL-EL4703-Instrumentasi Biomedis 8

Electrocardiograph

ARL-EL4703-Instrumentasi Biomedis 9

Holter Monitor

ARL-EL4703-Instrumentasi Biomedis 10

Dipole Model

ARL-EL4703-Instrumentasi Biomedis 11

Standard Location ?

ARL-EL4703-Instrumentasi Biomedis 12

ECG Lead Configurations • A pair of electrodes, or a combination of several electrodes

through a resistive network that gives an equivalent pair is called a lead.

• A vector that connects a lead electrode pair is the lead vector.• If the cardiac vector M is known, the voltage generated at any

lead can be easily computed.

Page 3: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

3

ARL-EL4703-Instrumentasi Biomedis 13

Frontal Plane Bipolar LeadsEinthovenTriangle

ARL-EL4703-Instrumentasi Biomedis 14

The Einthoven Triangle

ARL-EL4703-Instrumentasi Biomedis 15

Lead I

ARL-EL4703-Instrumentasi Biomedis 16

Lead II

ARL-EL4703-Instrumentasi Biomedis 17

Lead III

ARL-EL4703-Instrumentasi Biomedis 18

Cardiac Vector Through the Cardiac Cycle As Seen By Leads I, II and III

Page 4: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

4

ARL-EL4703-Instrumentasi Biomedis 19

Cardiac Vector Through the Cardiac Cycle As Seen By Leads I, II and III

ARL-EL4703-Instrumentasi Biomedis 20

Cardiac Vector Through the Cardiac Cycle As Seen By Leads I, II and III

ARL-EL4703-Instrumentasi Biomedis 21

Cardiac Vector Through the Cardiac Cycle As Seen By Leads I, II and III

ARL-EL4703-Instrumentasi Biomedis 22

UnipolarMeasurements:Wilson Central Terminal

• Three additional leads are used for frontal plane measurements.

• These are the measurements at the specific electrode, with respect to a reference electrode

• One commonly used reference electrode is the Wilson Central Terminal, obtained through a resistive network, combining limb electrodes

• The new set of leads obtained by combining the standard limb electrodes to the Wilson terminal form the augmented leads

• These leads provide additional vector views of cardiac depolarization in the frontal plane. Unlike leads I, II, III, the augmented leads utilize WCT, a central negative terminal. This virtual "electrode" is calculated by the EKG computer to measure vectors originating roughly at the center of the heart.

Note that the voltage at Wilson’s terminal is zero (why?)

ARL-EL4703-Instrumentasi Biomedis 23

Wilson’s Central Terminal

ARL-EL4703-Instrumentasi Biomedis 24

Augmented Leads: aVR

21IIIVVaVR −−=

Page 5: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

5

ARL-EL4703-Instrumentasi Biomedis 25

Augmented Leads: aVL

21IIVVaVL −=

ARL-EL4703-Instrumentasi Biomedis 26

Augmented Leads: aVF

2I

IIVVaVF −=

ARL-EL4703-Instrumentasi Biomedis 27

All Frontal Leads

ARL-EL4703-Instrumentasi Biomedis 28

Frontal Lead

ARL-EL4703-Instrumentasi Biomedis 29

Transversal Lead

ARL-EL4703-Instrumentasi Biomedis 30

12 Leads ECG Recording

Page 6: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

6

ARL-EL4703-Instrumentasi Biomedis 31 ARL-EL4703-Instrumentasi Biomedis 32

ECG Intrumentation

• Single Channel ECG

ARL-EL4703-Instrumentasi Biomedis 33

ECG Intrumentation

Electrode TransducerCharacteristic :

acquiring signal with amplitude between 0.01mV – 3mVanticipate impedance till > 5 MΩsmall current leakages < 1 µ-Aresponse frequency 0.05 – 150 Hz

ARL-EL4703-Instrumentasi Biomedis 34

ECG Intrumentation

ECG Amplifier schematicsRight leg driven loop- noise reducing- patient protection- Reduce Common Mode

Voltage

ARL-EL4703-Instrumentasi Biomedis 35

ECG Intrumentation

• Instrumentation Amplifier

ARL-EL4703-Instrumentasi Biomedis 36

ECG Intrumentation

• AD620 single chip instrumentation amplifier

Page 7: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

7

ARL-EL4703-Instrumentasi Biomedis 37

ECG IntrumentationHigh Pass Filter Second Amplifier

Low Pass Filter 20 Hz

Clamper

Low Pass Filter 40 Hz

Analog subsystemARL-EL4703-Instrumentasi Biomedis 38

ECG Intrumentation

Digital Subsystem

ARL-EL4703-Instrumentasi Biomedis 39

ECG Intrumentation

Display Unit• Galvanometer• Osciloskop• CRT• LCD• PC + Monitor• Paper chart• PDA/HP display

ARL-EL4703-Instrumentasi Biomedis 40

Some Problems in ECG

Noise & interferences

ARL-EL4703-Instrumentasi Biomedis 41

Some Problems in ECG

• Souces of interference in an ECG trace– base line wander : patient movement, electrode

reposition, dry electrode, static buildup around patient

– AC noise (50 Hz) : powerline/common mode interfrence

– intermittent signal : lead connection not tight and secured, dry electrode, damage cable or lead wire

– Other Electrical interference (EI)

Another ECG System

Page 8: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

8

ARL-EL4703-Instrumentasi Biomedis 43

Glossary of Terms• AED : Automated External Defibrillator – Auto diagnosis with voice

directed treatment.• EKG/ECG: ElectroCardioGram – skin surface, heart monitor• Holter Monitor: Portable device for continuously monitoring the electrical

activity of the heart for at least 24 hours. Can be external or implantable.

• Defibrillation : Delivering a therapeutic dose of electrical energy to the heart.• T-wave alterans : A change in the shape of the heartbeat signal on an every

other beat basis that is not apparent to the naked eye.• Right Leg Drive : An operational amplifier deriving common mode voltage is

used to invert the common-mode signal and drive it back into thepatient through the right leg.

• RFI : Radio Frequency Interference• ESD : Electro Static Discharge

ARL-EL4703-Instrumentasi Biomedis 44

ECG Markets ECG

Professional Healthcare Consumer

Diagnostic

Above Diagnostic

AED

Defibrillators

Commercial Fitness Equipment

Home Products

line battery line battery

Holter Monitor

ARL-EL4703-Instrumentasi Biomedis 45

Diagnostic ECG (Clinical Use)

AD8220

InstrumentationAmplifier

+5V

-5V

A B

C

24.9kΩ24.9kΩ

AD7980

ADum240X

BlackFin

ADC

DSP

iCoupler

REF 22μF

ReferenceADR435

4.12kΩ

Additional Channels

Additional Channels

AD8618

+5V

4.7μF

14kΩ

+5V

+5V

-5V +5V

-5V

REF/2

REF/2

1MΩ

47nF

10kΩ

10kΩ

2.2pF

2.2pF

10pF

G=14

12.7kΩ 12.7kΩ

866kΩ

68pF

499kΩ

OP2177

+5V

OP2177+5V

op amps-5V

-5V

AD8618

+5V

14.5kΩ

14.5kΩ

68nF

22nF

REF/2

Low Pass 5th Order Filter at 157Hz

switchADG601

From Lead I

From Lead IIFrom Lead III

ADum240X

AD8618

+5V

19.3kΩ

19.3kΩ

33nF

33nF

220pF

REF/2Pacing Artifact

Detection Circuitry

15kΩ

Lead Detection

50kHz

866kΩ

ADG620

REF/2

AD8618

+5V

57.6kΩ1.18kΩ 14kΩ

High Pass Filter 0.033Hz G=50

1.15kΩ

4.99kΩ

33Ω

10nF

ARL-EL4703-Instrumentasi Biomedis 46

Diagnostic ECG In-amp + Right Leg Drive

AD8220

InstrumentationAmplifier

+5V

-5V

A B

C

24.9kΩ24.9kΩ

4.12kΩ

4.7μF

+5V

-5V +5V

-5V

REF/2

10kΩ

10kΩ

2.2pF

2.2pF

10pF

G=14

12.7kΩ 12.7kΩ

866kΩ

68pF

499kΩ

OP2177

+5V

OP2177+5V

op amps-5V

-5V

switchADG601

From Lead I

From Lead IIFrom Lead III

220pF

15kΩ

866kΩ

ADG620

ARL-EL4703-Instrumentasi Biomedis 47

Diagnostic ECG Filters + Pace Detection

AD8618

+5V

4.7μF

14kΩ

REF/2

REF/2

1MΩ

47nF

12.7kΩ

AD8618

+5V

14.5kΩ

14.5kΩ

68nF

22nF

REF/2

Low Pass 5th Order Filter at 157Hz

switchADG601

From Lead IIFrom Lead III

AD8618

+5V

19.3kΩ

19.3kΩ

33nF

33nF

220pF

REF/2Pacing Artifact

Detection Circuitry

Lead Detection

50kHz

866kΩ

ADG620

REF/2

AD8618

+5V

57.6kΩ1.18kΩ 14kΩ

High Pass Filter 0.033Hz G=50

1.15kΩ

4.99kΩ

33Ω

10nF

ARL-EL4703-Instrumentasi Biomedis 48

Diagnostic ECG ADC + Isolation + Processing

AD7980

ADum240X

BlackFin

ADC

DSP

iCoupler

REF 22μF

ReferenceADR435

Additional Channels

Additional Channels

+5V

ADum240X

33Ω

10nF

Page 9: Cardiac Conduction System (2) The ECG (1) - · PDF file(Electrocardiogram) Achmad Rizal BioSPIN ARL-EL4703-Instrumentasi Biomedis 2 Cardiac Conduction System (1) ... Cardiac Conduction

9

ARL-EL4703-Instrumentasi Biomedis 49

Low Power, Low Cost, Wireless ECG (Holter Monitor)

ESDDefibrillation

Protection

ADuC7022

ADF702x*

ESDDefib

Protect

RLElectrode

RAElectrode

RLElectrode

AD623G=10.6

High-Pass Pole0.5Hz

0.47μF

5pF

681kΩ

499kΩ

5.23kΩ 5.23kΩ

475Ω 10kΩ

108pF

Anti-alias Filter-3dB, 1592 Hz

AdditionalDigital Filter

Level ShiftAnti-Alias

Total Gain ~ 220

G = 22.05

AD8641

AD8603

Dependent on Frequency Band Used (WMTS or ISM)

ARL-EL4703-Instrumentasi Biomedis 50

Low Cost, Low Power AED

Filterand

ProtectionNetwork

ADR365

AD7685

HighVoltage

Discharge

PowerControl

ADP1712

AD8220/4AD8606

AD8605

PatientPads

Li IonBattery

ADuC70xxor

Blackfin®

LCD Display

Single poleanti-alias

filter

Digital Filtering

Blanking

ARL-EL4703-Instrumentasi Biomedis 51

Exercise Heart Rate Monitor(Example: treadmill with heart rate monitor)

AD8692AD8692

REF

REF REF

AD8553

AD8691

High Pass Filter

ADuC70xxREF

InputProtection

+5V

40 Hz Low Pass Filter