CARBON DIOXIDE Angiography and Intervention - Slides

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    CARBON DIOXIDEANGIOGRAPHY

    ANDINTERVENTION

    CARBON DIOXIDEANGIOGRAPHY

    ANDINTERVENTION

    Jim Caridi MDUniversity of Florida

    Gainesville, FL

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    WHYCO2 ?

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    CO2 ADVANTAGES

    1. Non-allergic 4. Low viscosity

    2. Non - nephrotoxic 5. Inexpensive

    3. Unlimited total 6. Minimal or no

    volumes discomfort

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    CO2 DISADVANTAGES

    1. Requires unique delivery system

    2. Invisible potential for undetected contamination

    3. Currently not suggested in cerebral vessels

    4. Bowel gas can interfere with abdominal images

    5. Can be more labor intensive

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    PERFORMING CO2

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    Invisible

    Buoyant Compressible

    TO PERFORM CO2 ONEMUST

    UNDERSTAND ITS UNIQUEPROPERTIES

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    INVISIBLE? CONTAMINATION

    1. CO2 cylinderRust, methane, H2O, particulate matter,

    carbonic acid

    2. Room air

    diffusivity

    malpositioned stopcock

    inadequate flushing

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    PREVENT CONTAMINATION

    1. Use a disposable source of

    medical grade CO2

    2. Use a closed non-compressed

    delivery system

    3. Eliminate stopcocks

    4. Glue connections

    5. Flush system 2-3 times

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    BUOYANT

    CO2 doesnt mix with blood - it displaces it

    CO2 rises to a non dependent position

    Anterior images easily visualized

    Posterior imaging depends upon displacement

    of blood

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    R

    L

    R

    L

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    CO2

    - BUOYANCY

    +

    ANATOMY OR EXCESSIVE VOLUME

    POTENTIAL TRAPPING

    VAPOR LOCK

    ISCHEMIA

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    PREVENT TRAPPING

    Prevent excessive volumes

    Monitor with fluoroscopy

    Wait between injections

    Aspirate if necessary

    ** CHANGE THE PATIENTS POSITION**

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    Excessive Volume = 1 large or multiple small injections

    without delay

    NEVER connect directly to a CO2 cylinder

    Deliver known volumes - closed non-compressed system

    Wait 1-2 min. between injections

    Limit volumes to < 100 ccs / injection

    Use stacking software program

    PREVENT EXCESSIVE VOLUMES

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    STACKING SOFTWARE

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    EXPLOSIVE DELIVERY

    Pain, N&V

    Reflux - potential trapping, neurotoxicity

    Vessel damage

    INDETERMINATE VOLUMES

    Can lead to accidental excessive volumes

    COMPRESSIBLECOMPRESSIBLE

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    PREVENT EXPLOSIVE

    DELIVERY

    Use a non-compressed

    closed system

    Purge catheter before

    definitive injection

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    NEUROTOXICITY

    NITROUS OXIDE

    ANESTHESIA

    COPD

    OTHER POTENTIAL CONCERNS

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    Iodinated contrast allergy

    INDICATIONS

    Renal insufficiency

    Arterial bleeding

    High volume contrast procedures

    Intervention

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    CONTRAINDICATIONS

    Supra-diaphragmatic arterial injections (intracranialCO2)

    Use with nitrous oxide anesthesia

    Known right to left shunts

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    DELIVERYDELIVERY

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    Non-compressed reservoir

    Delivery syringe

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    Non-compressed closed system

    Non-compressed - for accurate volume

    Hand injection - purge catheter to prevent explosive

    delivery

    One way valves - prevent reflux and necessity to

    remove delivery syringe

    Glued components - helps prevent air embolus

    (Venturi effect)

    DELIVERY

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    IMAGING TECHNIQUES

    1. Dose - in general 1.5 - 2 times I contrast

    2. Radiopaque Catheter -

    3. Selective injections / Nitroglycerine for poor flow

    4. Image at 3-4 frames/sec using a 60 ms pulse width

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    5. Monitor with fluoroscopy

    6. Wait 1-2 minutes between injections

    7. If the CO2 bolus is broken up use stacking software

    8. Elevate the area of interest

    IMAGING TECHNIQUES

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    Low viscosity

    Easier use of smaller catheters, microcatheters Can inject in-between catheter and wire

    Detection of bleeding, AVF, collaterals

    Portal vein visualization

    Unlimited volume

    Reflux

    Ability to identify ostium or origin of vessel

    INTERVENTION PRINCIPLES

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    Tuohy Borst Fitting

    Forcefully inject CO2

    Use a large syringe

    small syringe - CO2 will simply compress

    wait 4-10 sec for CO2 to exit catheter

    INTERVENTION

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    INTERVENTION

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    DETECTION OF BLEEDING

    1. CO2 - low viscosity

    2. Little or no capillary phase to obscure CO2

    3. CO2 expands

    4. CO2 is not diluted by blood

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    VENOUS DX & TREATMENT

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    VENOUS DX & TREATMENT

    Slow steady injection of 15-30 cc (fluoroscope heart for

    washout

    CO2 is not diluted by blood and can opacify central

    veins more readily from a peripheral approach

    Venous PTA and stent placement

    IVC filter placement

    Translumbar/hepatic vein catheter placement

    Ultra fine needle splenoportography

    PICC placement

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    ARTERIAL INTERVENTION Reflux - can opacify the entire vessel including ostium

    for more precise stent placement

    Can inject between guide cath and catheter or wire

    and catheter to check placement withoutcompromising position for PTA and stenting

    Can perform repeated injections without the fear ofrenal failure

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    CO GUIDED TIPS

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    CO2

    GUIDED TIPS

    Hepatic vein evaluation

    Wedged hepatic venogramIntraparenchymal portal venogram

    Entry site verificationPortal venogram

    Parenchymal tract evaluation

    Balloon and stent positioning

    Post procedure portogram

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    CONCLUSION

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    CONCLUSION

    CO2 angiography is safe when used appropriately

    CO2 has unique properties as a contrast agent

    It can be used alone or in addition to other contrast

    agents

    It is useful in both diagnosis and treatment