CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com...

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CAPABILITIES

Transcript of CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com...

Page 1: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

CAPABILITIES

Page 2: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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Capabilities

Table of ContentsIntroduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3

Chromatography . . . . . . . . . . . . . . . . . . . . . . . . . . 5

LC/MS/MS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8

UPLC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

Gas Chromatography . . . . . . . . . . . . . . . . . . . . . . 11

Inorganic Chemistry . . . . . . . . . . . . . . . . . . . . . . . 12

General Chemistry . . . . . . . . . . . . . . . . . . . . . . . . 14

Microbiology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19

Nutritional Supplement Panel . . . . . . . . . . . . . . 21

Page 3: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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We offer comprehensive testing solutions for the Dietary Supplement and Food & Beverage industries. As a full-service, ISO/IEC 17025 accredited, third-party contract laboratory, we provide services to multinational brands through the entire supply chain including: raw material suppliers, contract manufacturers, brand manufacturers, retail brand owners and etc.

We utilize robust and accurate methods specifically designed for assay analysis of complex matrix samples by Ultra Performance Liquid Chromatography (UPLC), Gas Chromatography, and specialized Mass Spec (LC-MS/MS and GC-MS/MS). We also offer trace metal and mineral testing services by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) and Direct Mercury Analyzer (DMA) as well as possess a vast Fourier Transform Infrared Spectroscopy (FTIR) identity testing library, and much more.

Whether you’re looking to test raw materials or finished goods, you can be confident that Dyad Labs will provide you with accurate, precise, and timely results.

Capabilities

Being born from manufacturing since 2008, we understand that we are a part of your supply chain and quality control program. Together, we are Dyad.

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dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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Capabilities

3 STAGES OF WHERE DYAD CAN BE A PART OF YOUR QUALITY CONTROL PROGRAM

IDENTITY FTIR Assay/Analytical Wet ID

PURITYMicrobials Allergens ICP-MS

Elemental/Toxicity Pesticides/Residual SolventsUPLC, LC MS/MS, GC, GC/MS/MS

STRENGTH Assay/AnalyticalLiquid Chromatography/Gas Chromatography

PURITYMicrobials Allergens UPLC, LC MS/MS, GC

Elemental/Toxicity Liquid Chromatography GC

STRENGTH Assay/Analytical Liquid Chromatography GC

COMPOSITION Assay/Analytical Liquid Chromatography GC

CONTAMINENTS Assay/Analytical Liquid Chromatography GC

1. Raw Materials***Verify Suppliers C of A

2. Finished Product Testing*** Verify Label Claim of Product

ACCELERATED STABILITY REAL TIME STABILITY

STRENGTH

AnalyticalLiquid Chromatography

Assay/AnalyticalLiquid Chromatography

MicrobialsGas Chromatography

Microbiology

PURITY

Microbials Elemental/ToxicityPesticides/Residual Solvents

Elemental/Toxicity ICP-MS, LC MS/MS GC MS

Pesticides/Residual Solvents

GC

3. Stability TestingEnables Manufacturers to establish Expiration date of Product*** New products are encourage to have atleast 6 months of data

Page 5: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

5

POTENCY TESTING VIA LIQUID CHROMATOGRAPHY

Verification of potency claims by liquid chromatography is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. Dyad Labs utilizes compendial methods, AOAC validated test methods and analytical methods developed by Dyad through its years of experience in product testing.

Capabilities – Chromatography

ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

Ultra-high performance liquid chromatography (UPLC) has evolved from high performance liquid chromatography (HPLC). Both techniques involve liquid chromatography used to separate the components from mixtures. UPLC differs from HPLC because smaller particle size columns are used. With smaller-particles sizes, there is increased pressure and the instrumentation itself is designed to allow for that. Smaller particle sizes allow for increased chromatographic efficiency and therefore a better and more resolved separation of peaks. With narrower peak shapes, run time can be decreased. All nine of our chromatographic systems at Dyad utilize UPLC instead of HPLC. Assays that we conduct with UPLC/UV detection include:

| Amino acids

| Creatine and related compounds

| Water-soluble vitamins

| Organic acids

| Fat-soluble vitamins

| Alkaloids (already referenced in water soluble vitamin section)

| Caffeine, theophylline, theobromine, catechins, theacrine, BHB

| Curcuminoids, ginsenosides, resveratrol

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Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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Capabilities – Chromatography

LC/MS/MS

LC/MS/MS combines the separation of components using liquid chromatography with the detection specificity of mass spectrometry. With all of the matrices we analyze and the complexity of them, this is a powerful technique. Compared to HPLC & UPLC, LC MS/MS’s added specificity is especially critical in analysis of finished good with low concentrations of compounds, although raw materials can be analyzed just as well. Combined with the specificity, because of the added sensitivity, samples can be diluted relatively more than occurs using UV detection, thus allowing mitigation of sample matrix problems. Some of the assays we analyze on these instruments include:

| Protein identification (whey, casein, pea, soy, rice)

| Methyl and cyanocobalamin

| Melamine

| Low concentrated water-soluble vitamins

| Fat-soluble vitamins (Vitamins D2, D3, K1, and K2: menaquinone-4 and -7)

WE OFFER ANALYSIS OF MORE THAN 350 COMPOUNDS USING MORE THAN 50 ASSAYS. OUR INSTRUMENTATION INCLUDES:

| LC/MS/MS

| UPLC

| PDA/UV/QDA

| GC/MS/MS - coming 4th quarter of 2018

| GC/FID - coming 4th quarter of 2018

Turn around times are from 5 - 7 Business Days

Rushes are accepted by a case by case basis

Page 7: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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POTENCY TESTING VIA LIQUID CHROMATOGRAPHY

UPLC & LC/MS/MS

Capabilities – Chromatography

Test Packages Reportable Compounds Turn around Times

Free Amino Acids

Histidine, Arginine, Taurine, Serine, Glutamine, Glycine, As-

partic Acid, Citrulline, Glutamic Acid, Beta Alanine, Threonine,

Alanine, Theanine, Proline, Cystine, Lysine, Tyrosine, Methi-

onine, Valine, Norvaline, Isoleucine, Leucine, Phyenylalanine,

Tryptophan

7 days

B Vitamins Package (UPLC) Thiamine, Riboflavin, Niacin, Niacinamide, Pyridoxine 7 days

B Vitamins Package (LC-MS/MS)Thiamine, Riboflavin, Niacin, Niacinamide, Pyridoxine, Pyri-

doxal-5’-phosphate7 days

Aflatoxins Total B1, B2, G1, G2 7 days

5-Methyltetrahydrofolic Acid+A44:E49 Cholecalciferol Pantothenic Acid

alpha-Ketoglutaric Acid Citrulline Pyridoxal-5’-Phosphate

alpha-Ketoglutaric Acid (on dried basis) Cyanocobalamin Pyridoxine

Arginine Ergocalciferol Pyridoxine HCI

Arginine (on dried basis) Folic Acid Riboflavin

Biotin Fructose Sucrose

Ca-5-Methyltetrahydrofolate Glucose Theacrine

Caffeine Methylcobalamin Thiamine

Calcium Pantothenate Niacin Thiamine HCl

Catechin Niacinamide

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dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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LC MS/MS

Capabilities – Chromatography

5-Methyltetrahydrofolic Acid Cyanocobalamin Niacinamide

Aflatoxin B1 ECG Dimer Ochratoxin A

Aflatoxin B2 ECGC Dimer-1 Pantothenic Acid

Aflatoxin G1 ECGC Dimer-2 Pea Protein

Aflatoxin G2 Ergocalciferol Phylloquinone

Aflatoxins - Total B1, B2, G1, G2 Folic Acid Pyridoxal-5’-Phosphate

Biotin Fructose Pyridoxine

Ca-5-Methyltetrahydrofolate Glucose Pyridoxine HCI

Calcium Pantothenate Glutaurine Riboflavin

Casein Protein Glyphosate Rice Protein

Catechin Lactose Soy Protein

Catechin Dimer Melamine Sucrose

Catechin Dimer Digallate Menaquinone-4 Thiamine

Catechin Dimer Gallate Menaquinone-7 Thiamine HCl

Catechin Tetramer Methylcobalamin Total Sugars

Catechin Trimer Methylcobalamin (on dried basis) Whey Protein

Catechin Trimer Gallate Milk Protein

Cholecalciferol Niacin

Page 9: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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UPLC

Capabilities – Chromatography

4-Hydroxy-L-Isoleucine Betaine HCL D-alpha-Tocopherol

5-Hydroxytryptophan beta-Tocopherol D-alpha-Tocopherol Acetate

Acesulfame K Calcium beta-Hydroxy beta-Methylbutyrate D-alpha-Tocopherol Succinate

Acetyl-L-Carnitine Calcium D-Glucarate delta-Tocopherol

Acetyl-L-Carnitine HCI Calcium D-Glucarate tetrahydrate Dicreatine Malate

Agmatine Capsaicinoids Dicyandiamide

Agmatine Nitrate Carnitine Disodium Creatine Phosphate

Agmatine Sulfate Carnitine HCl DL-alpha-Tocopherol Acetate

Ajmalicine Carnitine Tartrate DL-alpha-Tocopherol Succinate

Ajmaline Catechins (Total) DMAE

Alanine Chlorogenic Acid DMAE Bitartrate

Alfalfa Choline EGCG

alpha-Lipoic Acid Choline Bitartrate Epicatechin (EC)

alpha-Tocopherol Choline Chloride Epicatechin Gallate (ECG)

alpha-Tocopheryl Acetate Citric Acid Erythritol

alpha-Tocopheryl Succinate Citrulline Malate Evodiamine

alpha-Yohimbine Citrulline Nitrate Forskolin

alpha-Yohimbine HCI Coenzyme Q10 Gallocatechin (GC)

Amentoflavone Corosolic Acid Gallocatechin Gallate (GCG)

Arginine alpha-Ketoglutaric Acid Corynanthine gamma-Aminobutyric Acid

Arginine Ethyl Ester Creatine gamma-Tocopherol

Arginine Ethyl Ester HCl Creatine Ethyl Ester Glucaric Acid

Arginine HCl Creatine Ethyl Ester HCI Gluconate

Arginine Nitrate Creatine HCI Glucosamine

Ascorbic Acid Creatine Monohydrate Glucosamine HCI

Ascorbyl Palmitate Creatine Nitrate Glucosamine Sulfate

Aspartame Creatine Pyruvate Glucosamine Sulfate 2KCl

Aspartic Acid Creatinine Glucosamine Sulfate Potassium Chloride

BCAAs Creatinol-O-Phosphate Glucuronolactone

Beta Alanine Curcumin Glutamic Acid

Beta Alanine HCI Creatinol-O-Phosphate Glutamic Acid HCI

beta-Hydroxy beta-Methylbutyrate Curcumin Glutamine

beta-Hydroxybutyrate Curcuminoids Glycine

Betaine Cystine Higenamine

Page 10: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

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UPLC, CONT.

Capabilities – Chromatography

Higenamine HCl NADH Serine

Histidine NaMethyltyramine Sodium alpha-Lipoic Acid

Histidine HCI Monohydrate NaMethyltyramine HCI Sodium beta-Hydroxybutyrate

Hordenine HCI Nitrate Sucralose

Huperzine A N-Methyltyramine HCl Synephrine

Hydroxycitric Acid Norvaline Synephrine HCl

Hyperoside Oleuropein Tartaric Acid

Isoleucine Ornithine Taurine

Isoleucine Nitrate Ornithine HCl Theanine

Isoquercitrin para-Aminobenzoic Acid Theobromine

L-5 Hydroxytryptophan Phenylalanine Theophylline

Lactic Acid Picamilon Thiamine Mononitrate

L-Dopa Proline Threonine

Leucic Acid Pterostilbene Total Ginsenosides

Leucic Acid (Ca salt) Pyridoxal-5’-Phosphate monohydrate Total Rhodiola Glycosides

Leucine Quercetin Total Rosavins

Leucine Nitrate Quercetin Dihydrate Total Tocopherols

Lysine Quercitrin Tryptophan

Lysine HCl Raspberry Ketone Tyramine

Maleic Acid R-beta-Methylphenylethylamine Tyrosine

Malic Acid Rebaudioside A Valine

Melatonin Resveratrol Vinburnine

Methionine Retinol Vincamine

Methylliberine Retinol Acetate Vinpocetine

Monosodium Glutamate Retinol Palmitate Xylitol

N-Acetyl Carnitine Ribose Yohimbine

N-Acetyl-L-Cysteine Rosarin Yohimbine Alkaloids

N-Acetyl-L-Glutamine Rosavin Yohimbine HCI

N-Acetyl-L-Methionine Rosin Yohimbine HCl Anhydrous

N-Acetyl-L-Tyrosine Rutin

NAD Salidroside

Page 11: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

11

POTENCY TESTING VIA GAS CHROMATOGRAPHY

Verification of potency claims by Gas chromatography is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. Dyad Labs utilizes compendial methods, AOAC validated test methods and analytical methods developed by Dyad through its years of experience in product testing.

Coming 4th quarter:

| Pesticides

| DHA & EPA

| Residual Solvents

Capabilities – Chromatography

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Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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Capabilities – Inorganic Chemistry

PURITY TESTING VIA INORGANIC

For analysis of heavy metals and minerals, we have two Agilent 7700 ICP-MS systems (Inductively-coupled plasma mass spectrometry). The ICP source converts the atoms of the elements in the sample to ions by high temperature. These ions are then separated by their mass and detected by the mass spectrometer. This process is highly sensitive, allowing for analysis down to concentrations in the parts-per trillion for some ions. The technology is reproducible, even when analyzing trace metals. In addition, interference removal and matrix tolerance is a critical part of our approach, which allows us to analyze different sample types. As a result, our customers have an accurate measurement of results, including heavy metal contami-nation and mineral composition.

Reportable Compound Method Turn around Times

Heavy Metals Package Arsenic, Cadmium, Lead, Mercury AOAC 993.14 5 days

Minerals Package

Calcium, Phosphorus, Magnesium, Zinc, Selenium, Copper, Cobalt, Manganese, Chromium, Potassium, Sodium, Tungsten, Iron, Boron, Lithium, Nickel, Tin, Antimony, Strontium, Molybdenum

5 days

Tungsten (W)

AOAC 993.14 5 days

Zinc (Zn) (on dried basis)

Indium (In)

Vanadium (V)

Iron (Fe)

Iron (Fe) on dried basis

Zinc (Zn)

Aluminum (Al)

Lead (Pb)

Antimony (Sb)

Lithium (Li)

Magnesium (Mg)

Magnesium (Mg) on dried basis

Arsenic (As)

Manganese (Mn)

Manganese (Mn) on dried basis

Barium (Ba)

Molybdenum (Mo)

Tin (Sn)

Page 13: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

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Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

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PURITY TESTING VIA INORGANIC, CONT.

Capabilities – Inorganic Chemistry

Reportable Compound Method Turn around Times

Boron (B)

AOAC 993.14 5 days

Nickel (Ni)

Boron (B) on dried basis

Cadmium (Cd)

Calcium (Ca)

Chromium (Cr)

Chromium (Cr) on dried basis

Calcium (Ca) on dried basis

Cobalt (Co)

Copper (Cu)

Phosphorus (P)

Phosphorus (P) on dried basis

Potassium (K) on dried basis

Potassium (K)

Selenium (Se)

Sodium (Na)

Sodium (Na) on dried basis

Strontium (Sr)

Mercury (Hg) DMA 5 days

RUSH SERVICE AVAILABLE 1-3 DAYS

Page 14: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

14

IDENTITY TESTING VIA GENERL CHEMISTRY

We offer testing on more than 100 different compounds using more than 20 different types of testing. Our instrumentation is extensive to cover all of this.

Testing includes:

| FTIR (identification; primarily for raw materials)

| Wet chemistry identification

ASSAY / ANALYTICAL TESTING VIA GENERL CHEMISTRY

| Proteins via nitrogen testing (Kjeldahl: Foss Kjeltec and Dumas: Leco TruMac)

| Mercury (using Milestone DMA-80)

| Fiber (Total Dietary Fiber using Ankom’s Fiber Analyzer)

| Fat (using acid hydrolysis on Foss Hydrotec/Soxtec)

| Karl-Fischer

| Loss on Drying

| Particle size distribution

| Bulk/Tap Density

| Water Activity

| pH

| Ash

| Specific gravity

| Viscosity

| Titrations

| Gluten and soy allergens

| Calories and carbohydrates (by calculation)

Capabilities – General Chemistry

Page 15: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

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Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

15

IDENTITY / POTENCY / PURITY TESTING VIA GENERL CHEMISTRY

Capabilities – General Chemistry

Type Method Reportable Compound Lead Time

Ash USP <281>/GL-588 Ash 5 days

Bulk Density USP <616>/GL-587 Bulk Density 5 days

Density USP <699> Density of Solids 5 days

DMA EPA 7473/GL-585 Mercury (Hg) 5 days

FTIR USP <197>/GL-511 Standard 2 days

Karl Fischer USP <921>/GL-578 Water Content 5 days

Loss on Drying USP <731>/GL-516 Loss on Drying 2 days

Loss on Drying USP <731>/GL-517 Loss on Drying 6 days

Loss on Ignition Current USP-NF Loss on Ignition 5 days

Nitrogen / Kjeldhal AOAC 2001.11/GL-542 Nitrogen 5 days

Nitrogen / Dumas AOAC 2001.11/GL-542 Protein 5 days

Organoleptic GL-552 Physical Stability 10 days

Particle Size Distribution USP <786>/GL-566 60 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 80 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 120 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 100 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 200 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 230 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 325 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 40 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 20 Mesh Residue 5 days

Particle Size Distribution USP <786>/GL-566 140 Mesh Residue 5 days

pH USP <791>/GL-563 pH 5 days

Specific Gravity USP <841> Specific Gravity 5 days

Tapped Density USP <616>/GL-586 Tapped Density 5 days

Titration Current FCC Iron (Fe) 10 days

Titration Current FCC Dextrose 10 days

Titration Current FCC Dextrose (on dried basis) 10 days

Titration Current USP-NF Dextrose Equivalent 10 days

Titration Current USP-NF Fumaric Acid 10 days

Total Solids Current USP-NF Total Solids 5 days

Page 16: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

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Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

16

IDENTITY / POTENCY / PURITY TESTING VIA GENERL CHEMISTRY

Capabilities – General Chemistry

Type Method Reportable Compound Lead Time

Water Activity AquaLab/GL-518 Water Activity 3 days

Wet ID FCC Monograph Cellulose Gum 5 days

Titration Current USP-NF Lactic Acid 10 days

Titration Current USP-NF Standard 10 days

Titration Current USP-NF Potassium Iodide 10 days

Titration Current USP-NF Boric Acid 10 days

Titration Current USP-NF Potassium Citrate 10 days

* Wet ID Current USP-NF Guar Gum 5 days

Wet ID Current USP-NF Acacia 5 days

Wet ID Current USP-NF Acetate 5 days

Wet ID Current USP-NF Titanium Dioxide 5 days

Wet ID Current USP-NF Hypophosphite 5 days

Wet ID Current USP-NF Iodide 5 days

Wet ID Current USP-NF Iron (Fe) 5 days

Wet ID Current USP-NF Iron Phosphate 5 days

Wet ID Current USP-NF Lactate 5 days

Wet ID Current USP-NF Zinc (Zn) 5 days

Wet ID Current USP-NF Zinc Gluconate 5 days

Wet ID Current USP-NF Zinc Oxide 5 days

Wet ID Current USP-NF Aluminum (Al) 5 days

Wet ID Current USP-NF Ammonium 5 days

Wet ID Current USP-NF Antimony (Sb) 5 days

Wet ID Current USP-NF Lithium (Li) 5 days

Wet ID Current USP-NF Magnesium (Mg) 5 days

Wet ID Current USP-NF Magnesium Oxide 5 days

Wet ID Current USP-NF Magnesium Phosphate 5 days

Wet ID Current USP-NF Manganese (Mn) 5 days

Wet ID Current USP-NF Calcium Carbonate 5 days

Wet ID Current USP-NF Barium (Ba) 5 days

Wet ID Current USP-NF Calcium Citrate 5 days

Wet ID Current USP-NF Benzoate 5 days

Wet ID Current USP-NF Calcium Lactate 5 days

Page 17: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

17

IDENTITY / POTENCY / PURITY TESTING VIA GENERL CHEMISTRY

Capabilities – General Chemistry

Type Method Reportable Compound Lead Time

Wet ID Current USP-NF Calcium Phosphate 5 days

Wet ID Current USP-NF Carrageenan 5 days

Wet ID Current USP-NF Bicarbonate 5 days

Wet ID Current USP-NF Carbonate 5 days

Wet ID Current USP-NF Pullulan 5 days

Wet ID Current USP-NF Bismuth 5 days

Wet ID Current USP-NF Bisulfite 5 days

Wet ID Current USP-NF Bitartrate 5 days

Wet ID Current USP-NF Borate 5 days

Wet ID Current USP-NF Chlorate 5 days

Wet ID Current USP-NF Chloride 5 days

Wet ID Current USP-NF Bromide 5 days

Wet ID Current USP-NF Nitrite 5 days

Wet ID Current USP-NF Chromic Chloride 5 days

Wet ID Current USP-NF Calcium (Ca) 5 days

Wet ID Current USP-NF Chromium Picolinate 5 days

Wet ID Current USP-NF Calcium Ascorbate 5 days

Wet ID Current USP-NF Citrate 5 days

Wet ID Current USP-NF Oxalate 5 days

Wet ID Current USP-NF Permanganate 5 days

Wet ID Current USP-NF Peroxide 5 days

Wet ID Current USP-NF Cobalt (Co) 5 days

Wet ID Current USP-NF Standard 5 days

Wet ID Current USP-NF Milk Thistle 5 days

Wet ID Current USP-NF Phosphate 5 days

Wet ID Current USP-NF Copper (Cu) 5 days

Wet ID Current USP-NF Copper Gluconate 5 days

Wet ID Current USP-NF Potassium (K) 5 days

Wet ID Current USP-NF Corn Starch 5 days

Wet ID Current USP-NF Potassium Bicarbonate 5 days

Wet ID Current USP-NF Potassium Phosphate 5 days

Wet ID Current USP-NF Potassium Sorbate 5 days

Wet ID Current USP-NF Dicalcium Phosphate 5 days

Page 18: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

18

IDENTITY / POTENCY / PURITY TESTING VIA GENERL CHEMISTRY

Capabilities – General Chemistry

Type Method Reportable Compound Lead Time

Wet ID Current USP-NF Dipotassium Phosphate 5 days

Wet ID Current USP-NF Disodium Phosphate 5 days

Wet ID Current USP-NF Silicon 5 days

Wet ID Current USP-NF Silicon Dioxide 5 days

Wet ID Current USP-NF Ferric Salts 5 days

Wet ID Current USP-NF Ferrous Fumarate 5 days

Wet ID Current USP-NF Silver 5 days

Wet ID Current USP-NF Ferrous Salts 5 days

Wet ID Current USP-NF Sodium (Na) 5 days

Wet ID Current USP-NF Sodium Bicarbonate 5 days

Wet ID Current USP-NF Sodium Chloride 5 days

Wet ID Current USP-NF Sodium Citrate 5 days

Wet ID Current USP-NF Gelatin 5 days

Wet ID Current USP-NF Xanthan Gum 5 days

Wet ID Current USP-NF Sulfate 5 days

Wet ID Current USP-NF Sulfite 5 days

Wet ID Current USP-NF Thaimine Mononitrate 5 days

Wet ID Current FCC Glyceryl Monostearate 5 days

Wet ID Current FCC Silicon Dioxide 5 days

Wet ID Current FCC Standard 5 days

Wet ID Current FCC Maltodextrin 5 days

Page 19: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

193

Capabilities – Microbiology

MICROBIOLOGY TESTING

No matter where materials and consumables fall into the supply chain, they are constantly being introduced to micro-organisms. Most microbes are harmless but there are some that can damage the human health, product quality, contaminate the environment and irreversibly change a product. Here at Dyad we offer the following Micrbobiology services.

For rapid microbiology testing, we use AOAC-approved Invisible Sentinel Veriflow technology for the detection of Salmonella, Listeria species and many more to come. This new platform utilizes PCR based technology with a much shorter turn-around-time (36-48 hours). Great for food companies who need to know if there products/raws/enviroment contains pathogens.

Type Method Lead Time

Pathogen / Microbial Activity

Aerobic Plate Count

USP <2021> 3 days

FDA BAM 3 days

AOAC 990.12 3 days

EP Purified Water 7 days

* Bacillus cereus GL-483 4 days

ColiformsFDA BAM 5 days

AOAC 991.14 3 days

* E. coli

FDA BAM 6 days

AOAC 991.14 4 days

USP <2021> 3 days

* EnterobacteriaceaeUSP <2021> 4 days

AOAC 2003.01 3 days

General Anaerobic Count Difco Manual 5 days

Gran Stain GL-492 3 days

* ListeriaFDA BAM 5 days

3M Petrifilm 3 days

* Pseudomonas aeruginosa USP <62> 4 days

* = pathogens

Page 20: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

20

Capabilities – Microbiology

Type Method Lead Time

Pathogen / Microbial Activity

* Salmonella

USP <2022> 4 days

FDA BAM 4 days

Invisible Sentinel Veriflow technology 4 days

* Staphylococcus aereusUSP <2022> 4 days

FDA BAM 3 days

Water Testing EP Purified Water 7 days

Molds

AOAC 997.02 6 days

AOAC 2014.05 6 days

FDA BAM 6 days

USP <2021> 6 days

Yeasts

AOAC 997.02 6 days

AOAC 2014.05 6 days

FDA BAM 6 days

USP (2021> 6 days

Yeasts and Molds

AOAC 997.02 6 days

AOAC 2014.05 6 days

FDA BAM 6 days

USP <2021> 6 days

Probiotic

Viable Probiotic Count (Spores, Yeast, etc.)

GL-470 7 days

Bacillus coagulans GL-471 7 days

Lactobacillus acidophilus GL-470 7 days

MICROBIOLOGY TESTING, CONT.

* = pathogens

Page 21: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

dyadlabs.com [email protected]

Phone +1.801.973.88241945 Fremont Drive Salt Lake City, UT 84104 USA

21

NUTRITIONAL SUPPLEMENT PANEL

Requires minimum of 100g of sample, Full Panel/NLEA

Capabilities

Test Method Sendout TAT (Business Days) Notes

Total Fatty Acids GC Yes 10 days Includes Saturated Fat, Trans Fat,

Monounsaturated Fat, and

Polyunsaturated Fat

Cholesterol AOAC Yes 10 days

Carbohydrates Calculation No 7 days Includes Ash and Loss on Drying

Dietary Fiber AOAC 991.43 No 7 days

Sugars LC-MS/MS No 7 days

Protein AOAC 2001.11/GL-542 No 7 days

Vitamin D LC-MS/MS No 7 days

Sodium AOAC 993.14/GL-500 No 5 days

Calcium AOAC 993.14/GL-500 No 5 days

Potassium AOAC 993.14/GL-500 No 5 days

Iron AOAC 993.14/GL-500 No 5 days

Total Vitamin A VALC_S Yes 10 days

Ascorbic Acid GL-607 No 7 days

B Vitamins Package GL-602 No 7 days Includes Niacin, Pyridoxine,

Thiamine, Riboflavin

Page 22: CAPABILITIES - Dyad Labsdyadlabs.com/wp-content/uploads/2018/10/dyad...dyadlabs.com infodyadlabs.com 1945 remont Drie 1.801.93.8824 Salt Lae City, UT 84104 USA 4 Capabilities 3 STAGES

1945 Fremont Drive Salt Lake City, UT 84104 USA

Phone +1.801.973.8824 Print +1.801.973.8800

dyadlabs.com

[email protected]