California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very...

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California Institute of Technology Annual Report 2003–2004

Transcript of California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very...

Page 1: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

California Institute of TechnologyAnnual Report 2003–2004

Page 2: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

In 2003, Caltech registered more U.S. patents than any other single university. Patent #6,669,793 Microstructurecontrolled shear band pattern formation in ductile metal/bulk metallic glass matrix composites prepared by SLR process-ing Patent #6,666,831 Method, apparatus and system for automation of body weight support training (BWST) of bipedlocomotion over a treadmill using a programmable stepper device (PSD) operating like an exoskeleton drive system froma fixed base Patent #6,665,013 Active pixel sensor having intra-pixel charge transfer with analog-to-digital converterPatent #6,664,039 Methods and compositions for modulating neurodegeneration Patent #6,660,926 Thermoelectricdevices based on materials with filled skutterudite structures Patent #6,660,844 Optical sensors of cell signaling Patent#6,660,255 Inhibition of gene transcription by polyamide DNA-binding ligands Patent #6,658,550 Pipelined asynchro-nous processing Patent #6,656,450 Macrocyclic magnetic resonance imaging contrast agents Patent #6,654,102Miniature optical sensor Patent #6,649,801 Anionic borate ligands and zwitterionic complexes formed therefrom Patent#6,649,350 Electrochemical sensor using intercalative, redox-active moieties Patent #6,642,537 Dual band QWIP focalplane array Patent #6,638,756 Chimeric cell-targeting pathogenic organism and method of therapeutic use Patent#6,635,417 Complex formation between DSDNA and oligomer of cyclic heterocycles Patent #6,633,696 Resonant opticalwave power control devices and methods Patent #6,633,671 Camera-based handwriting tracking Patent #6,633,331High-speed CCD array camera with random pixel selection Patent #6,631,333 Methods for remote characterization of anodor Patent #6,630,290 Lithography using quantum entangled particles Patent #6,627,469 Methods for forming semi-conductor lenses on substrates Patent #6,625,569 Real-time spatio-temporal coherence estimation for autonomous modeidentification and invariance tracking Patent #6,625,368 Titanium-indiffusion waveguides and methods of fabricationPatent #6,624,265 Ruthenium metal alkylidene complexes coordinated with triazolylidene ligands that exhibit higholefin metathesis activity Patent #6,623,937 Programmed cell death antagonist protein Patent #6,622,872Micromachined membrane particle filter using parylene reinforcement Patent #6,621,687 Micro-supercapacitor Patent#6,620,264 Casting of amorphous metallic parts by hot mold quenching Patent #6,615,076 Neural prosthetic using tem-poral structure in the local field potential Patent #6,613,910 One-pot synthesis of group 8 transition metal carbene com-plexes useful as olefin metathesis catalysts Patent #6,612,743 Wavelength division multiplexed optical solitons Patent#6,612,535 MEMS valve Patent #6,610,999 Multiple stage high power diode Patent #6,610,626 Highly active metathesiscatalysts generated in situ from inexpensive and air stable precursors Patent #6,610,540 Low oxygen culturing of cen-tral nervous system progenitor cells Patent #6,610,367 Use of an array of polymeric sensors of varying thickness fordetecting analytes in fluids Patent #6,609,017 Processed neural signals and methods for generating and using themPatent #6,608,726 Solid immersion lens structures and methods for producing solid immersion lens structures Patent#6,608,668 Sub miniaturized laser doppler velocimeter sensor Patent #6,608,228 Two-photon or higher-order absorbingoptical materials for generation of reactive species Patent #6,607,740 Enzyme-mediated modification of fivrin for tissueengineering Patent #6,606,122 Single chip camera active pixel sensor Patent #6,603,473 Detail data pertaining to theshape of an object surface and related methods and systems Patent #6,600,565 Real-time evaluation of stress fields andproperties in line features formed on substrates Patent #6,598,750 Micromachined membrane particle filter using pary-lene reinforcement Patent #6,598,455 Non-inertial calibration of vibratory gyroscopes Patent #6,596,267 Methods andcompositions to prevent formation of adhesions in biological tissues Patent #6,594,586 Incorporation of contextual infor-mation in object identification Patent #6,594,061 Acceleration-insensitive opto-electronic oscillators Patent #6,593,731Displacement transducer utilizing miniaturized magnet and hall junctionQWIP focal plane array Patent #6,593,110Checkpoint-activating oligonucleotides Patent #6,593,065 Method of fabricating nanometer-scale flowchannels andtrenches with self-aligned electrodes and the structures formed by the same Patent #6,592,735 DNA sequencingmachine with improved cooling characteristics Patent #6,592,689 Fractional variation to improve bulk metallic glassforming capability Patent #6,590,197 Fabricating a hybrid imaging device Patent #6,589,728 Methods for isolation andactivation of, and control of differentiation from, stem and progenitor cells Patent #6,589,684 Direct methanol feed fuelcell and system Patent #6,587,180 Adjustable liquid crystal blazed grating deflector Patent #6,586,785 Aerosol siliconnanoparticles for use in semiconductor device fabrication Patent #6,586,207 Overexpression of aminoacyl-tRNA syn-thetases for efficient production of engineered proteins containing amino acid analogues Patent #6,584,845 Inertial sen-sor and method of use Patent #6,583,881 Lithography using quantum entangled particles Patent #6,583,702Quadrupole mass spectrometer driver with higher signal levels Patent #6,583,672 Method for controlling bias in anactive grid array Patent #6,583,399 Optical resonator microsphere sensor with altering Q-factor Patent #6,582,208Bladeless pump Patent #6,580,851 Resonator fiber bidirectional coupler Patent #6,580,532 Opto-electronic techniquesfor reducing phase noise in a carrier signal by carrier supression Patent #6,580,503 Particle sizing and concentrationsensor using a hollow shaped beam Patent #6,580,337 MEMS switch Patent #6,580,089 Multi-quantum-well infraredsensor array in spatially-separated multi-band configuration Patent #6,579,683 Artery- and vein-specific proteins anduses therefor Patent #6,579,068 Method of manufacture of a suspended nitride membrane and a microperistaltic pumpusing the same Patent #6,578,966 Computer-based 3D visual field test system and analysis Patent #6,576,899 Directdetection of low-energy charged particles using metal oxide semiconductor circuitry Patent #6,576,113 Method of elec-troplating of high aspect ratio metal structures into semiconductors Patent #6,574,501 Assessing blood brain barrierdynamics or identifying or measuring selected substances or toxins in a subject by analyzing Raman spectrum signals ofselected regions in the eye Patent #6,573,897 Real-time, interactive animation of deformable two- and three-dimensionalobjects Patent #6,571,603 Method of resolving analytes in a fluid #6,570,617 CMOS active pixel sensor type imaging sys-tem on a chip Patent #6,567,598 Titanium-indiffusion waveguides Patent #6,567,436 Opto-electronic oscillators havingoptical resonators Patent #6,567,157 Fast mixing condensation nucleus counter Patent #6,566,496 Neurogenin Patent#6,563,039 Thermoelectric unicouple used for power generation Patent #6,562,567 Method of detecting a nucleic acidPatent #6,560,030 Solid immersion lens structures and methods for producing solid immersion lens structures Patent#6,559,724 Techniques for enhancing gain in a quasi-optic grid array Patent #6,559,125 Polyamide-alkylator conjugatesand related products and method Patent #6,555,842 Active pixel sensor with intra-pixel charge transfer Patent#6,555,692 Preparation and use of bifunctional molecules having DNA sequence binding specificity Patent #6,555,337

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we wield aninfluence far out of proportionto our size, influence that isfelt both in andbeyond theacademe.

Page 4: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

December 31, 2004, marked the end of

my term as chairman of Caltech’s Board

of Trustees. What an exciting four years it

was, both for me personally and for the

Institute.

One of my most important—and

most gratifying—responsibilities as board

chairman was helping to plan and direct

“There’s only one. Caltech,” our $1.4

billion fund-raising campaign. I am very

pleased with how this ambitious effort has

progressed since its public launch in

October 2002. By the end of last fiscal

year, we had raised $979.5 million toward

our goal—not bad for a school with only

about 20,000 living alumni. The effect of

these campaign funds on the Caltech

community is already starting to be felt.

New professorships, scholarships, and fel-

lowships are being funded; old buildings

are being renovated and planned buildings

are moving closer to construction; and

much-needed scientific equipment is

being purchased. I have every confidence

that we will continue to make steady

progress over the remaining three years of

the campaign, and that our outstanding

priorities will be funded.

During the past four years, I also

had the pleasure of welcoming 12 new

trustees to the board, six in the last aca-

demic year alone. Joining us in 2003–04

were John D. Diekman, the founder and

managing partner of 5AM Ventures of

Menlo Park, California; Los Angeles Times

publisher John P. Puerner; Clara Spalter

Miller, the principal of Regulus

International Capital Corporation in

Greenwich, Connecticut (and a Caltech

alumna); John W. Mack, president of the

Los Angeles Urban League; Lewis W. van

Amerongen of LvA Enterprises, Inc.; and

Marc I. Stern, president of TCW, Inc. This

seemed to me an unusual rate of change,

even for our dynamic board, and it

prompted me to do some research into

how this group has evolved since I gradu-

ated from Caltech.

In 1954, I discovered, the board had

only 24 voting members; today, there are

56. All but one of those 24 lived in

Southern California; today our trustees

come from all over the country (and one

lives overseas). The 1954 board was all

male and all Caucasian; today’s board is

21 percent female, and has several African

American and Asian members. These

changes in the board’s composition reflect

similar developments in the campus com-

munity. The Institute’s student body has

L E T T E R F R O M T H E C H A I R M A N

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grown from 579 undergrads and 427

graduate students in 1954 to 896 under-

grads and 1,276 graduate students today.

In 1954, Caltech had only two female

students (both of them in graduate pro-

grams); today, we have 282 female under-

grads and 356 female grad students. Our

professorial faculty has also grown, from

168 in 1954 to 283 today. Of particular

interest to me was the fact that while

today we have 19 Caltech alumni on the

board, 50 years ago there was only one:

Arnold O. Beckman, who passed away last

April at the age of 104.

In fact, Dr. Beckman was our first

alumnus-trustee—a pioneer in this as in

so much else in his life. Over the course of

an almost 80-year association with the

Institute, he wore just about all the hats

there are to wear. He was a graduate

student (PhD ’28); a faculty member until

1940, when he left to found his innovative

company, Beckman Instruments; and the

first alumnus to serve as board chairman,

a job he carried out superbly from 1964 to

1974. His personal service to the Institute

was exceeded only by his financial gen-

erosity: among his many gifts to Caltech

were four buildings, a professorship, the

Beckman Scholar programs, and the

Mabel Beckman Prize. His influence was

felt not only in what he gave, but in who he

was—in the way his philosophy guided his

dealings with everyone he encountered.

The Caltech community is incalculably

greater for his having been a part of it.

I have turned the helm of the board

over to my successor, Kent Kresa, chair-

man emeritus of Northrop Grumman

Corporation and a Caltech trustee since

1994. Kent has always approached his

board service with great enthusiasm and

vigor, and I have no doubt that he will

bring the same energy to this new posi-

tion. I leave our dedicated fellow trustees

in his capable hands. I am confident that

together they will bring the campaign to a

successful end, and—more importantly—

ensure the Institute’s continued preemi-

nence in scientific research and education.

Benjamin M. Rosen

Chairman, Caltech Board of Trustees 2001–04

2/3California Institute of Technology

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L E T T E R F R O M T H E P R E S I D E N T

If you have picked up a Caltech publication

in the past two years, you will probably

recognize “There’s only one. Caltech”

as the slogan of our current fund-raising

campaign. This slogan is meant as a

reminder that Caltech is unique in the sci-

entific community because of our distinc-

tive mixture of certain key characteristics.

By some measures, for instance, we are

a small school—our full-time faculty

number fewer than 300, our student body

about 2,100. Yet we wield an influence far

out of proportion to our size, influence

that is felt both in and beyond the

academe. No other institution of our size,

for instance, can count so many Nobel

laureates among its faculty and alumni:

30 as of last October, when professor

Hugh David Politzer received the 2004

Nobel Prize in Physics. And no other

single university registered as many U.S.

patents as we did in 2003: 141. (Only the

entire University of California system

registered more.) One reason this small

place can have such a big impact is that

our faculty have many more resources

available to them than our 124-acre cam-

pus can contain. We operate an impressive

array of off-campus and space-based

observatories examining radiation at many

wavelengths, which allows our investiga-

tors to follow their scientific curiosity into

realms unavailable in Pasadena.

Recently, some of our staff were

putting together a new brochure about

these off-campus facilities, and were

trying to decide what to call it. The title

they came up with—“There’s only one

Caltech, but it’s not all in one place”—is,

of course, a variation of our campaign

slogan; but I think it also might have made

a good slogan for the Institute’s 2003–04

academic year. During that period, much

that was newsworthy about Caltech

research occurred away from Pasadena—

sometimes very far away indeed.

A fitting subtitle for 2003–04 might

have been “the year of JPL.” With several

missions returning a wealth of new data

within months of each other, the Jet

Propulsion Laboratory last year surpassed

even its own earlier successes. The good

news began to arrive in January, with the

flawless landings of the Spirit (January 3)

and Opportunity (January 24) rovers on

Mars. These two remarkable vehicles

completed their primary three-month

missions in April, and as of September

2004 were still in good health and working

double overtime. Among their many

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4/5California Institute of Technology

findings is evidence that a body of salty

water once covered at least some of the

red planet in the distant past.

Another of last year’s very successful

space missions was GALEX, the Galaxy

Evolution Explorer, an orbiting space

telescope designed to observe galaxies

in ultraviolet light across 10 billion years

of cosmic history. GALEX is an excellent

example of the many fruitful collaborations

between Caltech and JPL: it’s a NASA mis-

sion whose principal investigator is Caltech

faculty member Christopher Martin. As of

October 2004, GALEX had completed about

half of its planned three-year mission; it

had surveyed 20 percent of the sky and col-

lected 1.5 terabytes of raw data (1.5 trillion

bytes). By the end of its mission, scientists

project, GALEX will have amassed a stun-

ning 30 terabytes of information about the

universe.

Yet another example of Caltech–JPL

synergy is the Spitzer Space Telescope, a

NASA mission managed by JPL with sci-

ence operations based on the Caltech

campus. Launched in August 2003, Spitzer

looks at the sky at infrared wavelengths.

The telescope is finding such things as a

never-before-seen globular cluster—a

bundle of stars dating back to the birth of

the Milky Way that may help tell us how

our galaxy formed. Spitzer can also see

dust clouds where planets may be forming

around other stars. Some of the clouds are

larger than expected—perhaps fed by

embryonic planets destroying one another

in collisions—suggesting that planetary

birth may be a longer and more chaotic

process than previously thought.

And under the heading of “delayed

gratification,” in July JPL’s Cassini mission

arrived at Saturn after a seven-year

voyage. Among the remarkable discoveries

that Cassini has made so far are a new

Saturnian ring and two previously unknown

moons. The spacecraft has also taken

the most revealing images yet of Saturn’s

mysterious moon Titan.

OUR FACULTY HAVE MANY MORE RESOURCES AVAILABLE

TO THEM THAN OUR 124-ACRE CAMPUS CAN CONTAIN.

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Far from being outdone by the space-

based telescopes, our ground-based

observatories also reported some amazing

discoveries last year. Using the 48-inch

Samuel Oschin Telescope at Palomar

Observatory, planetary scientist Mike

Brown and his colleagues identified a

planetoid they’ve dubbed Sedna (after the

sea goddess in Inuit mythology). At more

than eight billion miles from Earth, Sedna

is by far the most distant body known to

orbit our sun, and is likely the largest

object found in the solar system since the

discovery of Pluto in 1930. Also using the

Oschin Telescope—this time with the pow-

erful new QUEST digital camera affixed to

it—astronomer George Djorgovski and his

team identified a quasar nearly six billion

light-years away. And over in Mauna Kea,

Hawaii, at the W. M. Keck Observatory,

astronomers Richard Ellis and Jean-Paul

Kneib discovered the most distant galaxy

yet detected. The investigators estimate

that this galaxy is 13 billion light-years

away, which means they are viewing it at

a time only 750 million years after the

Big Bang, when the universe was barely

5 percent of its present age.

As exciting as these discoveries are,

Caltech space science promises even

more revelations in the future, when the

new Thirty Meter Telescope (TMT) is

completed. Building on the successful

partnership behind the Keck Observatory,

we are once again collaborating with

the University of California (this time

adding the U.S. and Canadian National

Observatories to the mix). The TMT, which

is currently in the design phase, will be

a truly astonishing optical/infrared instru-

ment, with nine times the light-gathering

capability of the twin Kecks and the ability

to deliver images 12 times sharper than

the Hubble Space Telescope, even though

it will be ground based. It will greatly

expand our understanding of how the

chemical elements were synthesized as

the universe expanded and how galaxies

assembled from the very earliest minia-

ture systems into the grand structures we

see today.

Caltech would not be able to under-

take visionary projects like the TMT with-

out the generous support of its friends—

in this case, the Gordon and Betty Moore

Foundation, which has donated a total of

$35 million ($17.5 million each to Caltech

and the University of California) to fund

the new telescope’s design. The Moore

Foundation’s contribution to the TMT

OUR GROUND-BASED OBSERVATORIES ALSO REPORTED SOME AMAZING DISCOVERIES LAST YEAR.

Page 9: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

project came to us as part of our “There’s

only one. Caltech” campaign, which has

been publicly under way for just over two

years. I’m glad to report that as of the end

of fiscal year 2004, we had raised close to

$1 billion—$979.5 million, to be exact—

toward our $1.4 billion goal. For a school

with only about 20,000 living alumni, this

is an ambitious goal; so I find our progress

gratifying.

Funds received through the campaign

are already having a significant impact

on our campus. Half of the Moores’ total

gift of $600 million comes as grants from

the Moore Foundation given over 10 years.

With these funds we have been able to

purchase some much-needed large equip-

ment: magnetic resonance imagers,

cryo-electron microscopes, and an X-ray

beamline at the Stanford accelerator.

We have also been able to establish new

programs like the Tectonics Observatory,

which aims to develop a dynamic model

that accounts for both earthquake motion

and the forces that drive that motion. The

Moores’ personal campaign contributions

have allowed us to maintain the Moore

Visiting Scholar program, have provided

postdoctoral and graduate fellowships,

and have made all-important contribu-

tions to our endowment.

One of our essential campaign goals

was to bring in funds to construct and

renovate buildings. We have been quite

successful at finding donors for these

projects. The earliest evidence of this is

the wonderful restoration of Dabney Hall

of the Humanities, which was completed

last September. Our next building priority

will be the Cahill Center for Astronomy

and Astrophysics, for which we have much

but not all the funding. We have also

secured the funding for the Walter and

Leonore Annenberg Center for Information

Science and Technology, which will be

located next to the Moore Laboratory of

Engineering. This building will house

Caltech’s new interdisciplinary effort to

study the nature, transformation, storage,

and manipulation of information. Pursuing

6/7California Institute of Technology

CALTECH WOULD NOT BE ABLE TO UNDERTAKE VISIONARY PROJECTS LIKE THE TMT WITHOUT THE GENEROUS SUPPORT OF ITS FRIENDS.

Page 10: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

these and other projects—like the long-

overdue renovation of the south student

houses, which is scheduled to begin in

June 2005—means that the Caltech

campus will be a multifocal construction

site for several years to come.

But buildings are just hollow shells

without people to animate them. Thus,

another major campaign priority has been

to raise funds for professorships, under-

graduate financial aid, and graduate

fellowships. Again, we have been quite

successful, with more than $94 million

raised so far in those three areas (includ-

ing $2 million for the very popular and

successful Summer Undergraduate

Research Fellowships program). We have

also raised $97 million in research

funds, a significant amount of which

will go to supporting the people who do

the research. One notable example of

this support is the $7.5 million gift from

the Kavli Foundation to establish the

Kavli Nanoscience Institute at Caltech,

a development that will greatly enhance

our capabilities in this important emerg-

ing field.

In addition to these developments in

research and fund-raising, 2003–04 also

brought considerable change to the

Caltech community. Benjamin M. Rosen

retired as chairman of Caltech’s Board of

Trustees, which he had headed up since

January 2001. During his tenure, Ben very

ably presided over the planning, launch,

and first two years of the “There’s only

one” campaign, a gift of service to his

alma mater for which we are all very

grateful. He has been succeeded by Kent

Kresa, chairman emeritus of Northrop

Grumman Corporation and a Caltech

board member since 1994. I am looking

forward to working with Kent to bring our

campaign to a successful conclusion over

the next three years.

On campus, Professor of Theoretical

Physics Steven Koonin stepped down after

nine years as provost to take the position

of chief scientist at BP. Paul Jennings,

emeritus professor of civil engineering

SCIENCE IS FUNDAMENTALLY A HUMAN ENDEAVOR, CREATIVE AND UNPREDICTABLE, ONE THAT FINDS ITS HIGHEST EXPRESSION IN BENEFITING HUMANKIND.

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and applied mechanics, succeeded him,

resuming a post he also held from 1989 to

1995. Vice President for Business and

Finance Albert G. Horvath left the Institute

to become the chief financial officer at

Columbia University. Art Elbert, associate

vice president for campus planning,

served as acting vice president for busi-

ness and finance while a search commit-

tee sought Al’s successor. A new vice pres-

ident, Dean W. Currie, was appointed in

December, and will be coming to Caltech

from Rice University in February 2005.

This past academic year also saw the

passing of five extraordinary scientists:

alumnus William H. Pickering, director

of JPL from 1954 to 1976 and a central

figure in the U.S. space race; Arnold O.

Beckman, the first Caltech alumnus

to serve as chairman of our board, and

a longtime benefactor; alumnus Edward B.

Lewis, winner of the 1995 Nobel Prize in

Physiology or Medicine; geologist Robert

P. Sharp, a leading authority on the

surfaces of Earth and Mars and a longtime

head of our geological and planetary

sciences division; and James A. Westphal,

a former director of Palomar Observatory

and leader of one of the original instru-

ment-building teams for the Hubble Space

Telescope. While we feel their absence

deeply, we know that in some sense they

are still with us in the students and col-

leagues they inspired.

When we remember men like these,

we are reminded of another—and perhaps

the most profound—way Caltech influ-

ences the world: by training future scien-

tists and engineers. If we did not take the

educational component of our mission so

seriously, the ranks of the scientific com-

munity would be significantly diminished

(and I would have far less news to report

in this publication). Our illustrious prede-

cessors also remind us of what could be

accomplished in an era much less techno-

logically sophisticated than ours. They saw

clearly that science is fundamentally a

human endeavor, creative and unpre-

dictable, one that finds its highest expres-

sion in benefiting humankind. It is a vision

that still guides Caltech today.

David Baltimore

President

8/9California Institute of Technology

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there’s onlyone caltech,but it’s notall in oneplace.

THE YEAR IN REVIEW

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the year in review and science headlines 2003 to 2004

OCTOBER 2003

Caltech Today, the Institute’s new online daily newspage,debuts. Drawing its news from a wide variety of sources,the page is a substantial upgrade to its predecessor, Tech Today.

10.14.03 The annual Biology Forum takes place inBeckman Auditorium. This year’s topic is “Rememberingthe Past, Imaging the Future—Diagnosing and TreatingAlzheimer’s Disease.” A panel of experts moderated byLos Angeles Times science writer Robert Lee Hotz discussesthe latest imaging techniques for visualizing pathology inthe brains of Alzheimer’s patients.

10.22.03 Caltech, JPL researchers unveil details on newtype of light detector based on superconductivity.

10.23.03 Alumnus Rahul Mahajan (BS ’92), a peace activistwho also holds a PhD in physics, gives the first address in the 2003–04 Social Activism Speaker Series, “The BushDoctrine at Home and Abroad: Militarism Meets‘Globalization.’”

10.24.03 John D. Diekman, founder and managing partnerof 5AM Ventures of Menlo Park, California, is elected toCaltech’s board of trustees.

NOVEMBER 2003

11.11.03 Caltech trustee Shirley Malcom opens the2003–04 Presidential Lecture Series on AchievingDiversity in Science, Math, and Engineering with a talkentitled “Let Nurture Take Its Course: Diversifying theTalent Pool for Science and Engineering.”

11.12.03 Gamma-ray bursts, X-ray flashes, and supernovaenot as different as they appear, researchers find.

SEISMOLOGICAL LABORATORYPASADENA AND SOUTHERN CALIFORNIA

1921

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12/13California Institute of Technology

11.14.03 GALCIT (Caltech’s Graduate AeronauticalLaboratories) observes its 75th anniversary with presenta-tions, tours, panel discussions, and social gatherings.

11.24.03 Caltech/UCLA study finds new clues to the originsof brain tumors.

Engineers announce new, more promising type ofelectrolyte for fuel cells.

DECEMBER 2003

12.11.03 Geophysicists gain new insights on Earth’s core-mantle boundary.

JANUARY 2004

01.15.04 Wilmot James, the Moore Visiting Professor ofHistory and Sociology, is the second speaker in theInstitute’s 2003–04 Presidential Lecture Series onAchieving Diversity in Science, Math, and Engineering. Histalk is entitled “Africa, Genomic Science, and Some Noteson the Evolution of Human Diversity.”

01.17.04 Caltech commemorates the 10th anniversary ofthe Northridge earthquake with “Learning from the Past,Planning for the Future,” a daylong campus event com-prising lectures, displays, movies, and children’s activities.

01.19.04 Caltech students revive a venerable, but long dor-mant, tradition: Mudeo. The event, which includes men’sand women’s wrestling matches, a tug-of-war, and awheelbarrow race, takes place on the muddy constructionsite that has temporarily replaced the athletic field.

01.27.04 Los Angeles Times publisher John P. Puerner iselected to the board of trustees.

WILLIAM KERCKHOFF MARINE BIOLOGICAL LABORATORYCORONA DEL MAR, CA

JET PROPULSION LABORATORYPASADENA, CA

1930

1944

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FEBRUARY 2004

Beckman Auditorium marks its 40th anniversary. A gift ofalumnus Arnold Beckman (PhD ’28) and his wife, Mabel,the Edward Durrell Stone–designed building is theInstitute’s premier venue for lecture and performing artsprograms.

02.02.04 Professor of Theoretical Physics Steven Kooninsteps down after nine years as Caltech’s provost, and alsobegins a leave of absence from his faculty post to assumea position in industry. Leonhard Professor of GeologyEdward M. Stolper agrees to serve as interim provost.

02.03.04 Herman Wouk, the Pulitzer Prize–winning authorof The Caine Mutiny and other novels, delivers the 2004Michelin Distinguished Lecture, “A Random Walk ThroughMy Literary Life.”

02.09.04 Engineers design revolutionary radar chip.

02.11.04 “Zombie” behaviors are part of everyday life,according to neurobiologists.

02.15.04 Researchers using Hubble and Keck Telescopesfind farthest known galaxy in the universe.

02.19.04 Planetary scientists find planetoid in Kuiper Belt;could be biggest yet discovered.

PALOMAR OBSERVATORYNORTH SAN DIEGO COUNTY, CA

1948

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14/15California Institute of Technology

02.25.04 The Leakey Speaker Series on Human Originsresumes for 2003–04 with “The Adaptable Hand-Axe andHuman Origins,” a lecture by Richard Potts, the director ofthe Smithsonian Institution’s Human Origins Program.Other speakers in this year’s series will be BerhaneAsfaw, director of the Middle Awash Research Project(April 7), and Nina Jablonski, the Irvine Chair and Curatorof Anthropology at the California Academy of Sciences(May 19).

02.25.04 Burmese activist Ka Hsaw Wa gives the secondaddress in the 2003–04 Social Activism Speaker Series.

02.26.04 The Office of the Registrar launches REGIS, itsnew web-based course enrollment system for Caltechstudents.

MARCH 2004

03.08.04 Neuroscientists discover fundamental scaling rule that differentiates primate and carnivore brains.

03.13.04 “Bob,” Caltech’s entry in the DARPA GrandChallenge desert road race, finishes 1.3 miles of course.

03.15.04 William H. Pickering dies. Director of JPL from1954 to 1976 and a central figure in the U.S. space race,Pickering was also a Caltech alumnus (BS ’32, MS ’33,PhD ’36) and professor.

03.15.04 Most distant object in solar system discovered;could be part of never-before-seen Oort cloud.

03.24.04 Beckman pH meter designated a National HistoricChemical Landmark.

OWENS VALLEY RADIO OBSERVATORYBIG PINE, CA

SUBMILLIMETER OBSERVATORYMAUNA KEA, HI

1958

1986

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03.27.04 Groundbreaking for the Combined Array forResearch in Millimeter-wave Astronomy (CARMA) facilityheld near Bishop, California.

APRIL 2004

04.06.04 Award-winning novelist Ian McEwan comes toCaltech as writer in residence. His three-day visit culmi-nates in a reading and book signing in BeckmanAuditorium on April 8.

04.15.04 Bernie Sanders, Vermont’s at-large member ofthe United States House of Representatives, discusses thePatriot Act at the third presentation of the 2003–04 SocialActivism Speaker Series.

04.27.04 Clara Spalter Miller (BS ’84), principal of RegulusInternational Capital Corporation in Greenwich,Connecticut, is elected to the board of trustees.

MAY 2004

05.06.04 Actor Mike Farrell visits campus as a lecturer inCaltech’s Social Activism Speaker Series.

05.06.04 Physicists successful in trapping ultracold neu-trons at Los Alamos National Laboratory.

05.18.04 Alumnus (PhD ’28) and Caltech board chairmanemeritus Arnold Beckman dies. The nationally recognizedinventor, scientist, philanthropist, and business leaderwas 104.

W.M. KECK OBSERVATORYMAUNA KEA, HI

COSMIC BACKGROUND IMAGERSAN PEDRO DE ATACAMA, CHILE

1991

1999

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05.27.04 Unexpected changes in Earth’s climate observedon the dark side of the moon.

JUNE 2004

06.11.04 Caltech’s 110th commencement is held onBeckman Mall. This year’s speaker is Carly Fiorina, chair-man and chief executive officer of Hewlett-Packard. 532degrees are awarded: 208 BS (109 of them with honor);156 MS; 2 Engineer; and 166 PhD.

06.27.04 Caltech’s first Research Science Institute beginson campus, continuing through August 7. This six-weekprogram for academically talented high-school sciencestudents is produced in cooperation with the Virginia-based Center for Excellence in Education, which for thepast 11 years has also sponsored a similar program atMIT.

06.20.04 Caltech holds its first-ever staff appreciationevent, “A Fair to Remember,” on Beckman Mall.

16/17California Institute of Technology

LASER INTERFEROMETER GRAVITATIONAL-WAVE OBSERVATORYHANFORD, WA & LIVINGSTON, LA

1999

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JULY 2004

07.08.04 Neuroscientists demonstrate new way to controlprosthetic device with brain signals.

07.19.04 Caltech and MIT propose measures to ensureaccuracy, accessibility in presidential election.

07.21.04 Edward B. Lewis (PhD ’42), winner of the 1995Nobel Prize in Physiology or Medicine for his ground-breaking studies of how genes regulate the developmentof specific regions of the body, dies at age 86.

07.21.04 San Andreas earthquakes have almost alwaysbeen big ones, paleoseismologists discover.

07.26.04 New class of reagents developed by chemical biologists for in vivo protein tracking.

07.27.04 John W. Mack, president of the Los Angeles Urban League, and Lewis W. van Amerongen of LvAEnterprises, Inc., are elected to the board of trustees.

AUGUST 2004

08.12.04 Chemists devise new, simpler way to make carbo-hydrates.

08.22.04 Geobiologists create novel method for studyingancient life forms.

08.30.04 Sand dune noise may be a resonance effect,mechanical engineer theorizes.

THE CENTER FOR INNOVATIVE TECHNOLOGIES (CIT)2

PASADENA, CA

2003

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18/19California Institute of Technology

THIRTY METER TELESCOPEIN DESIGN AND SITE-PLANNING PHASE

R A N K I N G S

2003 Caltech registers more patents than any other singleuniversity in the nation. (Only the entire UC system regis-ters more.)

JANUARY 2004 Kiplinger Report names Caltech “the bestvalue in education.”

FEBRUARY 2004 Caltech places 12th among the top 15 U.S.institutions ranked in the “Best Places to Work forPostdocs” survey conducted by The Scientist.

APRIL 2004 Caltech rises in U.S. News & World Report’s “BestGraduate Schools” rankings, placing sixth among topengineering schools in the nation, as well as in the top 10in six engineering specialties:

computer, #6 (up from #10)electrical, #4 (up from #7)environmental, #5 (up from #8)mechanical, #4 (up from #8)aeronautical, #3 (unchanged)chemical, #4 (unchanged)

NOVEMBER 2004 The Scientist ranks Caltech #1 on its top-10 list of “Best Places to Work in Academia.”

Caltech is the fourth-best university in the world, accord-ing to the UK-based Times Higher Education Supplement.

Professor of Political Science Michael Alvarez and the Voting Technology Project are named to the“Scientific American 50” by Scientific American magazine,which honors 50 individuals, teams, companies, and other organizations whose accomplishments in research, business, or policy making during 2003–04 demonstrateoutstanding technological leadership.

SEPTEMBER 2004

Paul C. Jennings, professor of civil engineering andapplied mechanics, emeritus, begins his second stint asCaltech’s provost (a position he also held from 1989 to1995). Jennings succeeds Steven Koonin, who resignedthe post in February.

09.01.04 International team of scientists establishes newInternet land-speed benchmark.

09.15.04 Albert G. Horvath resigns as vice president forbusiness and finance to take a position at ColumbiaUniversity. Arthur J. Elbert, associate vice president forcampus planning, will serve as acting vice president whilea search committee looks for Horvath’s successor.

09.15.04 Biologists uncover new facts about odor detectionin insects; findings could lead to more effective repellents.

09.17.04 Dabney Hall of the Humanities is rededicated afterundergoing extensive refurbishing over the past year.

OCTOBER 2004

10.05.04 Professor of Theoretical Physics Hugh DavidPolitzer receives the Nobel Prize in Physics.

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J P L H I G H L I G H T S

Even by the standards of its often history-making activi-ties, the Jet Propulsion Laboratory enjoyed an extraordi-nary year in 2004, as several of its missions achievedhigh-profile milestones.

Engineers and scientists were jubilant when the twin MarsExploration Rovers landed successfully in January,embarking on cross-country ambles in search of evidenceof past water on the red planet. During the year, therovers sent home more pictures than all other Mars sur-face missions combined, surpassed their mission goalsmany times over, and chalked up many billions of hits ontheir websites.

After a seven-year journey from Earth and several flybysof other planets, the Cassini spacecraft fired its mainengine for an hour and a half in July to drop into Saturn’sorbit. In October, the spacecraft made a close pass byhaze-shrouded Titan, Saturn’s largest moon and a primetarget of the mission. At the end of December, Cassinireleased Huygens, an instrumented probe provided by theEuropean Space Agency. Huygens is targeted to descendto the surface of Titan in mid-January 2005.

The Stardust spacecraft took the best-ever pictures of acomet nucleus when it passed close to comet Wild 2 inJanuary, and also collected samples of cometary dust thatwill be returned to Earth in 2006. In September, theGenesis spacecraft brought a cargo of solar wind samplesback to Earth. Although the spacecraft’s parachutes failedto open, most of the samples were retrieved.

Two JPL instruments became operational on NASA’s Earth-orbiting satellite Aura in July. The TroposphericEmission Spectrometer is a first-of-its-kind infrared sen-sor that studies the lowest region of Earth’s atmosphere,while the Microwave Limb Sounder monitors ozone andother chemicals in the atmosphere.

Throughout the year, two space telescopes launched in2003—the Spitzer Space Telescope and the GalaxyEvolution Explorer—studied the universe in infrared andultraviolet wavelengths, respectively.

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D E V E L O P M E N T H I G H L I G H T S

Caltech received a total of $98,864,175* in cash and securities in fiscal year 2004, including more than $13million from the estates of 31 individuals; just over $50million from foundation donors; and more than $5 millionfrom corporations. Twenty-eight percent of all alumnimade gifts supporting the Institute. Alumni, CaltechAssociates, trustees, and other individuals contributed in excess of $8,180,000 in current-use, restricted, andunrestricted gifts.

As of September 30, 2004, $979,641,341 had been raised through the “There’s only one. Caltech” campaign,and significant progress was made toward many campaign goals:

> The restoration of Dabney Hall was completed in sum-mer 2004. This project brought the building’s appear-ance in line with its original design and reestablished itas home to Caltech’s humanities program.

> Fred Kavli and the Kavli Foundation committed a totalof $7.5 million to establish the Kavli NanoscienceInstitute. This support will help position Caltech at theleading edge of nanoscale science and engineering bycreating new research opportunities and attractingexceptional faculty and students.

> Groundbreaking at the planned site for the CombinedArray for Research in Millimeter-wave Astronomy(CARMA) took place in March 2004. The $15 millionCARMA project entails moving the telescopes of theOwens Valley Radio Observatory and the Berkeley-Illinois-Maryland Association to Cedar Flat in easternCalifornia’s Inyo Mountains to create a powerful newarray of 15 telescopes.

> The Sherman Fairchild Foundation approved a $10 million grant in support of the Cahill Center forAstronomy and Astrophysics. Architect Thom Maynewas retained to design the building, which is tentativelyscheduled to begin construction in mid-2006.

> The Annenberg Foundation awarded a $25 milliongrant for the construction of the Walter and LeonoreAnnenberg Center for Information Science andTechnology. This building will serve as the headquar-ters of Caltech’s new Information Science andTechnology initiative.

> The Gordon and Betty Moore Foundation approved several grants toward the foundation’s $300 millioncampaign commitment: $25.4 million to fund program-ming, laboratory equipment, research facilities, and staffing of the Kavli Nanoscience Institute; $14.2million to enable scientists at Caltech and Stanford tocollaborate on the construction of a high-intensity X-ray beam line at the Stanford Synchrotron RadiationLaboratory; $13.2 million to establish the TectonicObservatory for field studies of key plate boundaries;and $17.5 million to fund the design-developmentphase of the Thirty Meter Telescope.

* This figure is based on the effective date of cash/securitiesreceived per the Council for Advancement and Support ofEducation reporting standards, and may differ from auditedfinancials.

20/21California Institute of Technology

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A W A R D S A N D H O N O R S

NATIONAL AWARDS AND HONORS

Council of the National Academy of Sciences, and Governing Board of the National Research Council, NATIONAL ASSOCIATE OF THE NATIONAL ACADEMIES:

Anneila I. Sargent, Benjamin M. Rosen Professor of Astronomyand Director, Owens Valley Radio Observatory

National Academy of Sciences, MEMBER:

Donald V. Helmberger, Smits Family Professor of Geological andPlanetary Sciences

Andrew E. Lange, Marvin L. Goldberger Professor of PhysicsStephen L. Mayo, Professor of Biology and Chemistry and Associate

Investigator, Howard Hughes Medical Institute

FOREIGN ASSOCIATE:

David J. Stevenson, George Van Osdol Professor of PlanetaryScience

National Academy of Sciences, Institute of Medicine, MEMBER:

Frances H. Arnold, Dick and Barbara Dickinson Professor ofChemical Engineering and Biochemistry

National Aeronautics and Space Administration, NASA EXCEPTIONAL SCIENTIFIC ACHIEVEMENT MEDAL:

Yuk L. Yung, Professor of Planetary Science

NASA OUTSTANDING LEADERSHIP MEDAL:

Charles Elachi, Vice President; Director, Jet Propulsion Laboratory;and Professor of Electrical Engineering and Planetary Science

National Institutes of Health, DIRECTOR’S PIONEER AWARD:

Robert Phillips, Professor of Mechanical Engineering and Applied Physics

Stephen R. Quake, Thomas E. and Doris Everhart Professor ofApplied Physics and Physics

National Outdoor Book Award, 2004 RECIPIENT,

NATURE AND ENVIRONMENT CATEGORY:

Kenneth G. Libbrecht, Professor of and Executive Officer for Physics

National Science and Technology Council, PRESIDENTIAL

EARLY CAREER AWARD FOR SCIENTISTS AND ENGINEERS:

Babak Hassibi, Associate Professor of Electrical EngineeringMark Simons, Associate Professor of GeophysicsBrian M. Stoltz, Assistant Professor of Chemistry

INTERNATIONAL AWARDS AND HONORS

Eleventh International Conference in Approximation Theory, VASIL A. POPOV PRIZE:

Serguei Denissov, Olga Taussky and John Todd Instructor inMathematics

Israel Academy of Sciences and Humanities, ALBERT

EINSTEIN ANNUAL LECTURER:

David Baltimore, President of Caltech and Professor of Biology

Japan Academy, 2004 JAPAN ACADEMY PRIZE:

Hiroo Kanamori, John E. and Hazel S. Smits Professor ofGeophysics

Moscow Mathematical Society, 2003 PRIZE:

Alexei Borodin, Professor of Mathematics

Royal Astronomical Society, 2004 MICHAEL PENSTON

ASTRONOMY PRIZE:

Clive Dickinson, Postdoctoral Scholar in Astronomy

Royal Society, FOREIGN MEMBER:

Peter M. Goldreich, Lee A. DuBridge Professor of Astrophysics and Planetary Physics, Emeritus

Royal Swedish Academy of Sciences, NOBEL PRIZE

IN PHYSICS:

Hugh David Politzer, Richard Chace Tolman Professor of Theoretical Physics

SC2003 Conference, 2003 GORDON BELL PRIZE, CORECIPIENT:

Jeroen Tromp, Eleanor and John R. McMillan Professor ofGeophysics and Director, Seismological Laboratory

Dimitri Komatitsch, Senior Research Fellow in GeophysicsChen Ji, Associate Scientist

Shanghai Institute for Advanced Studies, Center for Mathematics and Theoretical Physics, KEYNOTE SPEAKER

AND HONORARY PROFESSOR:

John H. Schwarz, Harold Brown Professor of Theoretical Physics

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Technion—Israel Institute of Technology, 2004–05 POLLAK

LECTURER:

Morteza Gharib, Hans W. Liepmann Professor of Aeronautics andBioengineering

AWARDS AND HONORS FROM PROFESSIONAL SOCIETIES

American Astronomical Society, 2004 JOSEPH WEBER AWARD

FOR ASTRONOMICAL INSTRUMENTATION:

Thomas G. Phillips, Altair Professor of Physics and Director,Caltech Submillimeter Observatory

American Crystallographic Association, KENNETH N.

TRUEBLOOD AWARD:

Richard E. Marsh, Senior Research Associate in Chemistry,Emeritus

American Geophysical Union, FELLOW:

Joseph L. Kirschvink, Nico and Marilyn Van Wingen Professor of Geobiology

Yuk L. Yung, Professor of Planetary Science

American Philosophical Association, 2004 ARTICLE PRIZE:

Alan Hájek, Associate Professor of Philosophy

American Society for Biochemistry and Molecular Biology / International Union of Biochemistry and Molecular Biology, WILLIAM C. ROSE AWARD:

Sunney I. Chan, George Grant Hoag Professor of BiophysicalChemistry, Emeritus

American Society of Civil Engineers, NORMAN MEDAL,

CORECIPIENT:

Fatemeh Jalayer, George W. Housner Postdoctoral Scholar inCivil Engineering

2004 THEODORE VON KÁRMÁN MEDAL:

Theodore Yao-Tsu Wu, Professor of Engineering Science, Emeritus

American Society of Mechanical Engineers, 2004 LIFETIME

ACHIEVEMENT AWARD:

Theodore Yao-Tsu Wu, Professor of Engineering Science, Emeritus

American Vacuum Society, Southern California Chapter, LEADING EDGE STUDENT SYMPOSIUM, FIRST PRIZE:

Kerry J. Vahala, Ted and Ginger Jenkins Professor of InformationScience and Technology and Professor of Applied Physics

Association for Symbolic Logic, PRESIDENT:

Alexander S. Kechris, Professor of Mathematics

Astronomical Society of the Pacific, ROBERT J. TRUMPLER

AWARD:

David Charbonneau, Millikan Postdoctoral Scholar in Astronomy

Franklin Institute, 2004 BENJAMIN FRANKLIN MEDAL IN

CHEMISTRY:

Harry B. Gray, Arnold O. Beckman Professor of Chemistry

2004 BOWER AWARD AND PRIZE FOR ACHIEVEMENT IN SCIENCE:

Seymour Benzer, James G. Boswell Professor of Neuroscience,Emeritus

Geological Society of America, 2004 ARTHUR L. DAY MEDAL:

Edward M. Stolper, William E. Leonhard Professor of Geology

Protein Society, 2005 STEIN AND MOORE AWARD, CORECIPIENT:

Alexander J. Varshavsky, Howard and Gwen Laurie SmitsProfessor of Cell Biology

FOUNDATION AWARDS

Peter Gruber Foundation, 2004 NEUROSCIENCE PRIZE:

Seymour Benzer, James G. Boswell Professor of Neuroscience,Emeritus

John Simon Guggenheim Memorial Foundation, FELLOW:

Joann M. Stock, Professor of Geology and Geophysics

Japan–United States Educational Commission, FULBRIGHT

GRANT:

Joann M. Stock, Professor of Geology and Geophysics

Mind Science Foundation, 2004 TOM SLICK RESEARCH AWARD

IN CONSCIOUSNESS, CORECIPIENT:

Christof Koch, Lois and Victor Troendle Professor of Cognitive andBehavioral Biology and Professor of and Executive Officer forComputation and Neural Systems

Melissa Sáenz, Postdoctoral Scholar in Biology

22/23California Institute of Technology

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David and Lucile Packard Foundation, FELLOWSHIP IN

SCIENCE AND ENGINEERING:

Re’em Sari, Associate Professor of Astrophysics and PlanetaryScience

Alfred P. Sloan Foundation, RESEARCH FELLOW:

Andrew W. Blain, Assistant Professor of AstronomyNathan M. Dunfield, Associate Professor of MathematicsSunil Golwala, Assistant Professor of PhysicsVadim Yu. Kaloshin, Associate Professor of MathematicsRe’em Sari, Associate Professor of Astrophysics and Planetary

ScienceTapio Schneider, Assistant Professor of Environmental Science and

Engineering

Wolf Foundation, 2004 WOLF PRIZE IN CHEMISTRY:

Harry B. Gray, Arnold O. Beckman Professor of Chemistry

CORPORATE AWARDS

Publishers Marketing Association, 2004 BENJAMIN FRANKLIN

AWARD:

Kenneth G. Libbrecht, Professor of and Executive Officer forPhysics

UNIVERSITY HONORS

Massachusetts Institute of Technology, MCGOVERN

INSTITUTE, EDWARD M. SCOLNICK PRIZE IN NEUROSCIENCE:

Mark Konishi, Bing Professor of Behavioral Biology

Phi Beta Kappa, 2004–05 VISITING SCHOLAR:

Elliot M. Meyerowitz, George W. Beadle Professor of Biology and Chair of the Division of Biology

University of Michigan, WILLIAM GOULD DOW DISTINGUISHED

LECTURER:

Charles Elachi, Vice President; Director, Jet Propulsion Laboratory;and Professor of Electrical Engineering and Planetary Science

University of Toronto, 2003–04 A. R. GORDON DISTINGUISHED

LECTURER IN CHEMISTRY:

Michael R. Hoffmann, James Irvine Professor of EnvironmentalScience and Dean of Graduate Studies

INSTITUTE HONORS

ENDOWED PROFESSORSHIPS:

Thomas J. Ahrens, Fletcher Jones Professor of GeophysicsDavid J. Anderson, Roger W. Sperry Professor of BiologyPamela Bjorkman, Max Delbrück Professor of BiologyJohn C. Doyle, John G Braun Professor of Control and Dynamical

Systems, Electrical Engineering, and BioengineeringJames P. Eisenstein, Frank J. Roshek Professor of PhysicsYizhao Thomas Hou, Charles Lee Powell Professor of Applied and

Computational MathematicsJoseph L. Kirschvink, Nico and Marilyn Van Wingen Professor

of GeobiologyDavid W.C. MacMillan, Earle C. Anthony Professor of ChemistryR. Preston McAfee, J. Stanley Johnson Professor of Business

Economics and ManagementMichael Ortiz, Dotty and Dick Hayman Professor of Aeronautics

and Mechanical EngineeringThomas G. Phillips, Altair Professor of PhysicsHugh David Politzer, Richard Chace Tolman Professor of

Theoretical PhysicsStephen R. Quake, Thomas E. and Doris Everhart Professor of

Applied Physics and PhysicsDouglas C. Rees, Roscoe Gilkey Dickinson Professor of ChemistryAres J. Rosakis, Theodore von Kármán Professor of Aeronautics

and Mechanical EngineeringAnneila I. Sargent, Benjamin M. Rosen Professor of AstronomyCharles C. Steidel, Lee A. DuBridge Professor of AstronomyPaul W. Sternberg, Thomas Hunt Morgan Professor of BiologyPaul O. Wennberg, R. Stanton Avery Professor of Atmospheric

Chemistry and Environmental Science and Engineering

Associated Students of the California Institute of Technology (ASCIT), 2004 TEACHING AWARDS:

Colin F. Camerer, Rea A. and Lela G. Axline Professor of Business Economics

K. Mani Chandy, Simon Ramo Professor and Professor of Computer Science

Alan Hájek, Associate Professor of PhilosophyKayoko Hirata, Lecturer in JapaneseFeng-Ying Ming, Lecturer in Chinese

TEACHING ASSISTANT AWARDS:

Dave Goulet, Graduate Student in Applied and ComputationalMathematics

Mihai Stoiciu, Graduate Student in MathematicsVictor Tsai, Undergraduate Student in Planetary Science

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Graduate Student Council, 2004 TEACHING AWARD:

Wilhelm Schlag, Professor of Mathematics

TEACHING ASSISTANT AWARD:

Francesco Ciucci, Graduate Student in Mechanical Engineering

MENTORING AWARD:

Kip S. Thorne, Richard P. Feynman Professor of Theoretical Physics

Richard P. Feynman Prize for Excellence in Teaching, RECIPIENT:

George R. Rossman, Professor of Mineralogy and DivisionalAcademic Officer for Geological and Planetary Sciences

STUDENT AWARDS(members of the class of 2004, unless otherwise noted)

AMASA BISHOP FELLOWSHIPS:

Alice Lin (class of 2005)Marin Markov (class of 2005)

CHURCHILL SCHOLARSHIP:

Po-Shen Loh

FULBRIGHT FELLOWSHIPS:

Rachel MedwoodSuzana Sburlan

HERTZ FELLOWSHIP:

Po-Shen Loh

NATIONAL DEFENSE SCIENCE

AND ENGINEERING FELLOWSHIPS:

Megan GuichardPaul HandJoseph JewellEric Lin

alumni:Diane BairstowDirk EnglundJoseph KooElaine OuRobb Rutledge

NATIONAL PHYSICAL SCIENCE

CONSORTIUM FELLOWSHIPS:

graduate students:Julie CaspersonSandra LeeChristine Richardson

NATIONAL SCIENCE FOUNDATION FELLOWSHIPS:

Peter FreddolinoPo-Shen LohNicholas Piro

graduate students:Orion CrisafulliJennifer DionneMelissa GriggsAlan KwanCrystal Shih

alumni:Deanna CarrickDirk EnglundSang LeeJia MaoFlorian MerkelIsaac MillerMiles ShumanVictoria Sturgeon

PAUL AND DAISY SOROS FELLOWSHIP:

Lizhou “Lisa” Wang

STRAUSS SCHOLARSHIP:

Andrea Vasconcellos (class of 2005)

THOMAS J. WATSON FELLOWSHIP:

Iram Bilal

24/25California Institute of Technology

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Page 46: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in
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48/49California Institute of Technology

BOARD OF TRUSTEES(as of January 2005)

Officers of the Board

Kent Kresa, ChairWalter L. Weisman, Vice ChairDavid Baltimore, President

Trustees

George L. ArgyrosChairman and CEO, Arnel and Affiliates

David BaltimorePresident, California Institute of Technology

G. Patricia BeckmanCommunity Leader

Gordon M. BinderManaging DirectorCoastview Capital

Paul A. BrestPresident, The William and Flora Hewlett Foundation

Eli BroadChairman, AIG SunAmerica Inc.

William H. DavidowFounding Partner, Mohr, Davidow Ventures

John D. DiekmanFounder and Managing Partner, 5 AM Ventures

Lounette M. Dyer

Arthur L. GoldsteinChairman and CEO (Retired), Ionics, Incorporated

William T. GrossChairman and Founder, idealab!

David D. HoDirector, The Aaron Diamond AIDS Research Center

Louise Kirkbride*

Kent KresaChairman Emeritus, Northrop Grumman Corporation

Edward M. LambertManagement Consultant

David Li LeeManaging General Partner, Clarity Partners, L.P.

York LiaoManaging Director, Winbridge Company Ltd.

Alexander LidowChief Executive Officer, International Rectifier Corporation

Ronald K. Linde*Independent Investor and Chairman of the Board,The Ronald and Maxine Linde Foundation

John W. MackPresident, Los Angeles Urban League

Shirley M. MalcomDirector, Education and Human Resources Programs,American Association for the Advancement of Science

Clara S. MillerPrincipal, Regulus International Capital Corporation

Peter W. MullinChairman, Mullin Consulting, Inc.

Philip M. NealChairman and Chief Executive Officer, Avery Dennison Corporation

Philip M. Neches*Consultant and Entrepreneur

Patrick H. Nettles, Jr.Executive Chairman, Ciena Corporation

Ronald L. Olson*Senior Partner, Munger, Tolles & Olson

Stephen R. Onderdonk*President and Chief Executive Officer (Retired), Econolite Control Products, Inc.

John P. PuernerPublisher, President, and Chief Executive Officer, Los Angeles Times

Sally Kristen RidePresident, Imaginary Lines, Inc.Ingrid and Joseph Hibben Professor of Physics, University of California, San Diego

Benjamin M. Rosen, Chairman Emeritus*Chairman Emeritus, Compaq Computer Corporation

Stephen A. RossCo-Chairman, Roll and Ross Asset Management CorporationFranco Modigliani Professor of Finance and Economics, Massachusetts Institute of Technology

Marc I. SternPresident, TCW, Inc.

Charles R. TrimbleCo-Founder, Trimble Navigation, Ltd.

Lewis W. van AmerongenLvA Enterprises, Inc.

Walter L. Weisman*Former Chairman and Chief Executive Officer, American Medical International, Inc.

Virginia V. WeldonSenior Vice President for Public Policy (Retired), Monsanto Company

Gayle E. WilsonNonprofit Consultant

Henry C. Yuen

Page 56: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

Senior Trustees

Victor K. Atkins*President, Atkins Company

Harold Brown, President EmeritusCounselor, Center for Strategic and International Studies (CSIS)

Walter BurkeTreasurer, Sherman Fairchild Foundation, Inc.

Jewel Plummer CobbPresident Emerita, California State University, Fullerton

Harry M. CongerChairman and Chief Executive Officer, Emeritus, Homestake Mining Company

Richard P. CooleyRetired Chairman, Seafirst Bank

Thomas E. EverhartPresident Emeritus, California Institute of Technology

Camilla Chandler FrostTrustee of the Chandler Trustand a Director and Secretary-Treasurer, Chandis Securities Company

Shirley M. HufstedlerSenior Of Counsel, Morrison & Foerster

Bobby R. InmanProfessor, Lyndon B. Johnson Centennial Chair in National Policy,LBJ School of Public Affairs, The University of Texas at Austin

William F. KieschnickPresident and Chief Executive Officer (Retired), Atlantic Richfield Company

Gordon E. Moore, Chairman EmeritusChairman Emeritus, Intel Corporation

Sidney R. Petersen*Chairman and Chief Executive Officer (Retired), Getty Oil Company

Stanley R. Rawn, Jr.Private Investor

Richard M. RosenbergChairman and Chief Executive Officer (Retired), Bank of America Corporation

Life Trustees

Robert AndersonChairman Emeritus, Rockwell International Corporation

Robert O. AndersonChairman and Chief Executive Officer (Retired), Atlantic Richfield Company

Stephen D. Bechtel, Jr.Chairman Emeritus and Director, Bechtel Group, Inc.

Benjamin F. BiagginiChairman (Retired), Southern Pacific Company

Donald L. BrenChairman of the Board, The Irvine Company

Charles C. GatesChairman of the Board, Cody Resources LP

William R. GouldChairman Emeritus, Southern California Edison Company

Philip M. HawleyPresident, P. M. Hawley, Inc.

Robert S. McNamaraPresident (Retired), The World Bank

Ruben F. Mettler, Chairman EmeritusRetired Chairman and Chief Executive Officer, TRW Inc.

Simon RamoCo-Founder and Director Emeritus, TRW Inc.

Arthur RockPrincipal, Arthur Rock and Company

Robert J. SchultzVice Chairman (Retired), General Motors Corporation

Mary L. ScrantonNonprofit Consultant

Dennis StanfillPrivate Investor

Charles H. TownesNobel Laureate and Professor in the Graduate School, Department of Physics, University of California, Berkeley

Harry WetzelChairman and Chief Executive Officer (Retired), The Garrett Corporation

Albert D. Wheelon

* Members of the Board of Trustees Audit Committee. Ronald K.Linde is chair; David Baltimore, Charles Elachi, Arthur J. Elbert,Paul C. Jennings, Dale M. Johnson, D. Richard Moyer, Sharon E.Patterson, and Harry M. Yohalem are standing attendees.

Page 57: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

50/51California Institute of Technology

Institute Administrative Council (as of December 2004)

David BaltimorePresident

Hall DailyAssistant Vice President for Government and Community Relations

Gary DicovitskyVice President for Development and Alumni Relations

Charles ElachiVice President; Director, JPL

Arthur J. ElbertActing Vice President for Business and Finance

Sandra EllTreasurer and Chief Investment Officer

Jean E. EnsmingerChair, Division of the Humanities and Social Sciences

Kenneth A. FarleyChair, Division of Geological and Planetary Sciences

David L. GoodsteinVice Provost

David GoodwinChair of the Faculty

Paul C. JenningsProvost

Margo Post Marshak Vice President for Student Affairs

Elliot M. MeyerowitzChair, Division of Biology

Richard M. MurrayChair, Division of Engineering and Applied Science

Robert L. O’RourkeVice President for Public Relations

Thomas W. SchmittAssociate Vice President for Human Resources

David A. TirrellChair, Division of Chemistry and Chemical Engineering

Thomas A. TombrelloChair, Division of Physics, Mathematics and Astronomy

Mary L. WebsterExecutive Assistant to the President andSecretary, Board of Trustees

Harry M. YohalemGeneral Counsel

Page 58: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

The mission of the California Institute of Technology is to expand human knowledge and benefit society throughresearch integrated with education. We investigate the most challenging, fundamental problems in science andtechnology in a singularly collegial, interdisciplinary atmosphere, while educating outstanding students tobecome creative members of society.

Annual Report 2003–2004©California Institute of TechnologyProduced by the Office of Public Relations

Writer/Editor: Barbara DiPalmaContributors: Michael Farquhar, Elena RudnevDesign: Denton Design Associates

PHOTO AND IMAGE CREDITS:

covers diagrams and titles of some of the 141 U.S. patents Caltech registered in 2003page 10 mosaic of 10 GALEX images of the Andromeda galaxy.

http://www.jpl.nasa.gov/page 14 02.09.04—http://www.chic.caltech.edu/

02.15.04—http://www.astro.caltech.edu/~kneib/z7/page 15 03.15.04—http://www.gps.caltech.edu/~mbrown/sedna/page 17 05.27.04—Earthshine Project, http://www.bbso.njit.edupage 18 07.21.04—http://www.gps.caltech.edu/~sieh/home.html

08.22.04— http://www.gps.caltech.edu/labs/newmanlab/page 20 http://www.jpl.nasa.gov/page 26 Andreas Koch & Laurent Larsonneur, Digital Studio France

Page 59: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

Neurogenin Patent #6,552,729 Automatic generation of animation of synthetic characters Patent #6,549,235 Singlesubstrate camera device with CMOS image sensor Patent #6,546,148 Circuitry for determining median of image portionsPatent #6,545,289 Wavelength-insensitive radiation coupling for multi-quantum well sensor based on intersubbandabsorption Patent #6,545,162 Method for the synthesis of pyrrole and imidazole carboxamides on a solid supportPatent #6,545,048 Compositions and methods of treating cancer using compositions comprising an inhibitor or endothe-lin receptor activity Patent #6,544,738 Detectably and removably tagged nucleic acids Patent #6,542,662 Mode translat-ing waveguide adapter for a quasi-optic grid array Patent #6,593,110 Checkpoint-activating oligonucleotides Patent#6,593,065 Method of fabricating nanometer-scale flowchannels and trenches with self-aligned electrodes and the struc-tures formed by the same Patent #6,592,735 DNA sequencing machine with improved cooling characteristics Patent#6,592,689 Fractional variation to improve bulk metallic glass forming capability Patent #6,590,197 Fabricating ahybrid imaging device Patent #6,589,728 Methods for isolation and activation of, and control of differentiation from,stem and progenitor cells Patent #6,589,684 Direct methanol feed fuel cell and system Patent #6,587,180 Adjustableliquid crystal blazed grating deflector Patent #6,586,785 Aerosol silicon nanoparticles for use in semiconductor devicefabrication Patent #6,586,207 Overexpression of aminoacyl-tRNA synthetases for efficient production of engineered pro-teins containing amino acid analogues Patent #6,584,845 Inertial sensor and method of use Patent #6,583,881Lithography using quantum entangled particles Patent #6,583,702 Quadrupole mass spectrometer driver with highersignal levels Patent #6,583,672 Method for controlling bias in an active grid array Patent #6,583,399 Optical resonatormicrosphere sensor with altering Q-factor Patent #6,582,208 Bladeless pump Patent #6,580,851 Resonator fiber bidi-rectional coupler Patent #6,580,532 Opto-electronic techniques for reducing phase noise in a carrier signal by carriersupression Patent #6,580,503 Particle sizing and concentration sensor using a hollow shaped beam Patent #6,580,337MEMS switch Patent #6,580,089 Multi-quantum-well infrared sensor array in spatially-separated multi-band configura-tion Patent #6,579,683 Artery- and vein-specific proteins and uses therefor Patent #6,579,068 Method of manufactureof a suspended nitride membrane and a microperistaltic pump using the same Patent #6,578,966 Computer-based 3Dvisual field test system and analysis Patent #6,576,899 Direct detection of low-energy charged particles using metaloxide semiconductor circuitry Patent #6,576,113 Method of electroplating of high aspect ratio metal structures intosemiconductors Patent #6,574,501 Assessing blood brain barrier dynamics or identifying or measuring selected sub-stances or toxins in a subject by analyzing Raman spectrum signals of selected regions in the eye Patent #6,573,897Real-time, interactive animation of deformable two- and three-dimensional objects Patent #6,571,603 Method of resolvinganalytes in a fluid Patent #6,570,617 CMOS active pixel sensor type imaging system on a chip Patent #6,567,598Titanium-indiffusion waveguides Patent #6,567,436 Opto-electronic oscillators having optical resonators Patent #6,567,157Fast mixing condensation nucleus counter Patent #6,566,496 Neurogenin Patent #6,563,039 Thermoelectric unicoupleused for power generation Patent #6,562,567 Method of detecting a nucleic acid Patent #6,560,030 Solid immersionlens structures and methods for producing solid immersion lens structures Patent #6,559,724 Techniques for enhancinggain in a quasi-optic grid array Patent #6,559,125 Polyamide-alkylator conjugates and related products and methodPatent #6,555,842 Active pixel sensor with intra-pixel charge transfer Patent #6,555,692 Preparation and use of bifunc-tional molecules having DNA sequence binding specificity Patent #6,555,337 Neurogenin Patent #6,552,729 Automaticgeneration of animation of synthetic characters Patent #6,549,235 Single substrate camera device with CMOS image sen-sor Patent #6,546,148 Circuitry for determining median of image portions Patent #6,545,289 Wavelength-insensitiveradiation coupling for multi-quantum well sensor based on intersubband absorption Patent #6,545,162 Method for thesynthesis of pyrrole and imidazole carboxamides on a solid support Patent #6,545,048 Compositions and methods oftreating cancer using compositions comprising an inhibitor or endothelin receptor activity Patent #6,544,738 Detectablyand removably tagged nucleic acids Patent #6,542,662 Mode translating waveguide adapter for a quasi-optic grid arrayPatent #6,540,895 Microfabricated cell sorter for chemical and biological materials Patent #6,539,801 Z-axis vibratorygyroscope Patent #6,538,793 Electronically tunable and modulatable quasi-optic grid oscillator Patent #6,537,498Colloidal particles used in sensing arrays Patent #6,536,213 Micromachined parylene membrane valve and pumpPatent #6,535,328 Methods and devices based on brillouin selective sideband amplification Patent #6,534,798 Surfaceplasmon enhanced light emitting diode and method of operation for the same Patent #6,534,295 Cell lysis device Patent#6,533,919 Hydrogen generation by electrolysis of aqueous organic solutions Patent #6,529,614 Advanced miniatureprocessing handware for ATR applications Patent #6,529,277 Optical devices based on resonant configurational effectsPatent #6,529,272 Techniques for characterizing cloud condensation nuclel Patent #6,529,085 Tunable, distributed, volt-age-controlled oscillator Patent #6,528,266 Nucleic acid mediated electron transfer Patent #6,526,823Microelectromechanical system sensor assembly Patent # #6,525,824 Dual beam optical interferometer Patent#6,524,837 Hydantoinase variants with improved properties and their use for the production of amino acids Patent#6,522,402 Apparatus and method for analyzing microscopic samples based on optical parametric oscillation Patent#6,521,967 Three color quantum well infrared photodetector focal plane array Patent #6,521,898 High-efficiency elec-tron ionizer for a mass spectrometer array Patent #6,521,541 Surface preparation of substances for continuous convec-tive assembly of fine particles Patent #6,521,451 Sealed culture chamber Patent #6,521,209 Bifunctional detectionagents Patent #6,521,206 Molecular sieve CIT-6 Patent #6,520,753 Planar micropump Patent #6,519,371 High-speedon-chip windowed centroiding using photodiode-based CMOS imager Patent #6,518,765 Multi-sensor electrometerPatent #6,518,078 Articles useful as optical waveguides and method for manufacturing same Patent #6,516,604 Micro-colloid thruster system Patent #6,515,702 Active pixel image sensor with a winner-take-all mode of operation Patent#6,515,292 High resolution electron projection Patent #6,515,084 High metathesis activity ruthenium and osmiummetal carbene complexes Patent #6,513,389 Technique for determining curvatures of embedded line features on sub-strates Patent #6,512,844 3D rendering Patent #6,511,859 IC-compatible parylene MEMS technology and its applicationin integrated sensors Patent #6,509,866 Fast chirp transform Patent #6,509,323 Linear cyclodextrin copolymersPatent #6,508,988 Combinatorial synthesis system Patent #6,506,906 Preparation and use of bifunctional moleculeshaving DNA sequence binding specificity Patent #6,506,025 Bladeless pump Patent #6,504,041 Synthesis of ruthenium

Page 60: California Institute of Technology · Caltech,” our $1.4 billion fund-raising campaign. I am very pleased with how this ambitious effort has progressed since its public launch in

California Institute of Technology

Pasadena, California 91105

California Institute of Technology

Annual R

eport 2003–2004