BY: COURTNEY MEDEIROSBME 28111/30/11

Coronary Stents

Coronary Artery Disease

Leading cause of death in United States for men and women

Caused by buildup of plaque in arteries Heart tissue is deprived of nutrientsRisk factors:

Age Gender Genes

Symptoms and Tests for Coronary Artery Disease

Symptoms: Vary in strength Chest pain Fatigue Shortness of breath Weakness

Tests: ECG Exercise Stress Test Nuclear Stress Test CT Scan Coronary Angiograph

Coronary Angioplasty with Stents

Common treatment for Coronary Artery DiseaseProcess:

Blockage is defined through coronary angiography Incision is made Cardiac catheter is guided to the heart through an artery of

the groin or arm Guide wire is manipulated to lie across the blockage Heparin is a given to thin the blood and prevent clotting Stent balloon catheter is transported along the guide wire and is positioned over the blockage Saline is pumped into the balloon to inflate it Balloon is inflated for 30 to 60 seconds to expand the stent

Stents

ExpandableMesh-like tubeInvented to overcome short comings of

regular coronary angioplasty Stays in artery permanently

Kinds of Stents

Uncoated Stents Bare metal

Drug-coated Stents Coated with Sirolimus Controlled release of medicine into tissue Drug limits overgrowth of natural tissue Anti-rejection-type medicine (10% vs 26%)

Pros & Cons

Pros Less invasive than open heart

surgery Short procedure Failure rate 1%

Cons Not a cure Aggravates kidney function Stents can’t be used in every

surgery Can be rejected by body

Questions?

Sources

http://www.heartsite.com/html/stent.html#superior

http://en.wikipedia.org/wiki/Coronary_stenthttp://www.mayoclinic.com/health/

angioplasty/MY00352/DSECTION=what%2Dyou%2Dcan%2Dexpect

http://www.cypherstent.com/cypher-stent/pages/index.aspx

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0004449/