BTO Kalender

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GUIDING GOOD IDEAS BTOs owners and partners: University of Bergen | Helse Bergen | Institute of Marine Research Bergen University College | Christian Michelsen Research | NIFES | UNIFOB | Nofima AS WWW.BERGENTO.NO PHOTO BY: TOR ERIK H. MATHIESEN DESIGN BY: HALTENBANKEN TEXT BY: BTO PRINTED BY: HAVEL This calendar presents a selection of commercialisations based on research carried out at the following research institutions in Bergen. • The University of Bergen www.uib.no • Helse Bergen AS www.helse-bergen.no • Institute of Marine Research www.imr.no • Bergen University College www.hib.no • National Institute of Nutrition and Seafood Research www.nifes.no • Christian Michelsen Research AS (CMR) www.cmr.no • UNIFOB AS www.unifob.no • Nofima Ingredients www.nofima.no Bergen is Norway’s second largest city. The beautiful West coast of Norway runs along the Bergen region, and it is along this coastline that the greatest values in Norway are created. BTO is part of Region Bergen – we support the region vision of creating a dynamic growth region characterised by knowledge, cooperation, and a commitment to develop. We welcome you to visit us at Marineholmen Technology Park. Bergen Teknologioverføring AS (BTO) Thormøhlensgate 51, 5006 Bergen Phone: +47 55 58 30 50 Fax: +47 55 58 30 56 E-mail: [email protected] www.bergento.no GUIDING GOOD IDEAS 2011 Calendar INTERACTIVE EDITION – LOOK FOR:

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BTO kalender 2011

Transcript of BTO Kalender

Page 1: BTO Kalender

guiding good ideas

BTos owners and partners: University of Bergen | Helse Bergen | Institute of Marine ResearchBergen University College | Christian Michelsen Research | NIFES | UNIFOB | Nofima AS

www.BergenTo.noPHoTo BY: Tor erik H. MaTHiesen design BY: HaLTenBanken TeXT BY: BTo PrinTed BY: HaVeL

This calendar presents a selection of commercialisations based on research carried out at the following research institutions in Bergen.

• TheUniversityofBergenwww.uib.no• HelseBergenASwww.helse-bergen.no• InstituteofMarineResearchwww.imr.no• BergenUniversityCollege www.hib.no• NationalInstituteofNutritionandSeafoodResearchwww.nifes.no• ChristianMichelsenResearchAS(CMR)www.cmr.no• UNIFOBAS www.unifob.no• NofimaIngredientswww.nofima.no

Bergen is Norway’s second largest city. The beautiful West coast of Norway runs along the Bergen region, and it is along this coastline that the greatest values in Norway are created.

BTO is part of Region Bergen – we support the region vision of creating a dynamic growth region characterised by knowledge, cooperation, and a commitment to develop.

WewelcomeyoutovisitusatMarineholmenTechnologyPark.BergenTeknologioverføringAS(BTO)Thormøhlensgate51,5006BergenPhone: +4755583050Fax: +4755583056E-mail: [email protected]

www.bergento.no

guiding good ideas

2011Calendarinteractive edition – look for:

Til informasjon. (denne teksten skal ikke trykkes)

Markøren må ikke være mindre enn 5x5 cm.Grunnet kontraktsfestede rettigheter kan markøren bare benyttes i BTOs kalender for 2011. Markøren kan på ingen måte videredistribueres/formidles. Det kan ikke gjøres backup av markøren, den skal slettes av Haltenbanken etter kalenderens ferdigstillelse.

Jan A JohnsenCEOARRG AS

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www.bergento.no Phone: +47 55 58 30 50

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* Isaac Newton, 4 January 1643. English physicist, mathematician, astronomer, natural philosopher, alchemist and theologian. Known for Newtonian mechanics, Universal gravitation.

Looking ForWard

IN DEcEmbEr 2010 bTO cElEbraTED OUr sIx yEars bIrThDay. a lot has happened during these years. bTO has evolved to become a full-service operation, employing many strategies to move research results in bergen to new products and services. bTO will continue to evolve – and in 2011 we are planning to expand our services even more – wait and see!

OUr rEgION has lONg TraDITIONs IN INTErNaTIONal TraDE, and has shown impressive abilities to adapt to new areas of trade. Today knowledge and information are the “hot goods” in international business – and again – our region has a competitive advantage. There are about 4000 researchers in bergen, performing cutting edge research for close to 4 billion kroner each year, that is more than 10 year FTE of research every day of the year!

TEchNOlOgy TraNsFEr Is a glObal acTIvITy and will continue to be so. The researchers and their institutions in bergen deserve to have the same level of support regarding these aspects as their international colleagues. bTO has recognised this and we are motivated to pursue new opportunities.

• at bTO we anticipate that most of the potential future blockbuster technologies will need to enter a global marketplace to unleash its potential. It will take the best brains, network and tools to get there. Future business development will rely on us being able to build and activate a national and international network of experienced business developers in order to effectively match market needs and opportunities to new technology and inventions.

guiding good ideas

Axl - A new diAgnostic And therApeutic tArget for cAncer

Axl is a receptor tyrosine kinase, a very important protein class for the development of drugs. The importance of Axl as a new diagnostic and therapeutic target for cancer was co-discovered by Lars A. Akslen, Professor of Pathology at the Gade Institute, University of Bergen, in collaboration with the team of Prof. James Lorens at BBB.

Professor akslen and his research group have shown that axl is an important prognostic factor for the survival of breast cancer patients. The invention consists of monoclonal antibodies that have been raised to bind human axl protein, and this has several potential commercial applications. The detection and targeted treatment of axl-expressing tumors represent an important new therapeutic strategy for breast cancer. This new discovery is patented and licensed to the biotech company bergenbio as with the purpose to 1) examine axl-expression in tumours as a diagnostic tool, and 2) develop axl-targeted therapeutica as a new treatment.

The research conducted by Professor akslen and bergenbio has resulted in a local commitment to gather an international consortium to finance and develop a new drug for cancer treatment.

lars a. akslen is also a senior consultant at the Department of Pathology, haukeland University hospital. he is leader of the Tumor biology research group, which has made an international impact within angiogenesis research. akslen’s project represents translational cancer research focused on molecular changes in malignant tumours and their relation to prognosis and therapeutic response. This has contributed to improved diagnostics and prognostics in different cancers.

from left: gerd lillian hallseth(technician), professor lars A. Akslen, ingunn M. stefansson (chief physician & Post.doc)

Professor Lars. a. akslen was awarded King olav’s Cancer research Prize in 2009.

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* galileo galilei, 15 February 1564. Italian physicist, mathematician, astronomer, and philosopher who played major role in the scientific revolution. Known for Kinematics, Dynamics, Telescopic observational astronomy, and heliocentrism.

ouTSTanding reSearch – The FoundaTion For innovaTion!

ImPrOvINg qUalITy OF lIFE. research results that are developed into commercial products or services give individuals access to inventions that may improve their quality of life. bTO’s responsibility is to help researchers and research institutions in bergen commercialize their research results, ensuring that knowledge and inventions benefit individuals, society and industry.

crEaTE yOUr OwN wOrKPlacE. you do not need to abandon a career as a researcher in order to create your own business. The two can be combined, and bTO can guide you through your options.

FUNDINg FOr ThE rEsEarch grOUP aND ThE INsTITUTE. commercialization of research results can lead to considerable synergies for the research group. bTO ensures that the researcher and the research environment get their share of profits that arise from the commercialization of the invention.

• bTO services include idea and project development and commercialization and legal advice, available to faculties, researchers and industries.

• bTO provides legal and market expertise, and the core business is to perform business development within broad range of areas.

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the hub bergen

The Hub Bergen is an incubator for social innovation, and offers access to inspiring collaborative work and meeting spaces for entrepreneurs and people with imaginative ideas. It is the first of its kind in Norway. The concept started in London, and is spreading rapidly throughout the world.

The hub is a place where non profit and for profit social change ideas build and scale into viable enterprises that address the complex problems we face, from poverty to climate change, for people and planet. The hub bergen is part of a global network of collaborative spaces where entrepreneurs and social innovators come together to realize their ideas for a sustainable society.

In bergen, they are just getting started and aim to support an increasing number of diverse people to actively engage with each other – locally and globally – in meaningful and innovative ways, creating imaginative and entre-preneurial initiatives for a radically better world. The goal is to borrow the best elements from members clubs, business incubators, innovation agencies, dynamic public spaces and think tanks to create a very different kind of facilitating & supporting place.

The hub bergen encourages those looking for an inspired space for working, meeting, innovating, learning and connecting to join them today.

< silje grastveit (founder)

Web: www.bergen.the-hub.netFacebook: the hub bergenTwitter: hubbergen

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* vilhelm Friman Koren bjerknes, 14. march 1862. Norwegian physicist and meteorologist, laid the foundation for the “bergen school of meteorology”, and founder of the modern practice of weather forecasting

SucceSS-FacTorS For STarTup coMpanieS

very few technology-based startup companies with growth-potential stemming from Norwegian research institution, manage to grow. This according to a recent master thesis by a bTO technology transfer professional. The thesis investigates why this is the case, and the extent to which various factors affect the growth to potential high-growth businesses from research institutions.

sElEcTED FINDINgs FrOm ThE sUrvEy aND aNalysIs shOw:

• businesses with high-growth potential must prioritize marketing strategies and customer choice better; the weakness that was expressed the most by the respondents was the companies tended to focus on a market that did not respond.

• The companies must be more precise with their deliveries; it is common that deliveries are delayed, which can lead to liquidity problems.

• boards without management; the board of startup companies provides too little direction for the company.

• vision-driven growth – apply the company vision into reality; many companies are indecisive and compromise their own vision. This can lead to misinterpretation, and is detrimental to the communication and profile in regards to the company’s customers

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ARRG AS is a full-range supplier of AR-solutions. The ARRG team – Jan A Johnsen (CEO, Creative Director), Ingerid Rødseth (PhD in information science), and Tor Gjøsæter (CTO, research fellow UIB) – has a unique combination of skills and experience that allows the company to capture the whole Value Chain: from software development over IT infrastructure establishment to digital content creation.

In collaboration with vg (Norway’s largest single-copy newspaper), arrg as launched their first product – arad – fall 2010 in a poster campaign for the motion picture “Trolljegerne”. arad is a cell phone application that allows the user to visualize digital contents during newspaper a reading. Once installed, the cell phone will recognize a printed marker through its camera and show the associated content on the cell phone screen. The contents can range from video and audio data to 3D-objects or animations. moreover, the cell phone user will be able to interact with the contents, e.g. scaling, rotating, or moving objects with finger gestures and cell phone movements.

arad will close the gap between print media and the digital world. Direct browsing of the advertiser website is also possible. although arad was primarily developed for print advertising, the possible range of applications is unlimited. arrg’s services also include content creation, server hosting, and advertising campaign management.

AugMented reAlity reseArch group As

To download you new app:

iPhone/iPod touCh:1. download arad in aPPstore for Free2. touch the application and activate the program

symbian/win mobiL:1. enter website ar.vg.no2. Click “Last ned”, and chose archive location on you cell3. Click “install”

when arad is installed and activated, direct the cell’s camera towards the cursor above. the screen on you cell will show “live” troll including instructions. you will also hear sound.

Til informasjon. (denne teksten skal ikke trykkes)

Markøren må ikke være mindre enn 5x5 cm.Grunnet kontraktsfestede rettigheter kan markøren bare benyttes i BTOs kalender for 2011. Markøren kan på ingen måte videredistribueres/formidles. Det kan ikke gjøres backup av markøren, den skal slettes av Haltenbanken etter kalenderens ferdigstillelse.

Jan A JohnsenCEOARRG AS

Web: www.arrg.noFacebook: arrg as, arad

Apple app store: arad

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* leonardo Da vinci, 15 april 1452. revered for his technological ingenuity, he is viewed as one of the greatest painters of all time and perhaps the most diversely talented person ever to have lived.

** georg Ossian sars, 20. april 1837. Norwegian marine researcher and zoologist, credited with the discovery of a number of new species, particularly mysids and ostracods, is credited with making the first serious studies in fisheries science.

You have an idea – noW WhaT?

OFFErINg cOmPETENT assIsTaNcE. as a general rule, any patentable research result is the property of your employer, i.e. the employing research institution. consequently, the individual researcher may not freely commercialize his or her invention. This has to do with changes in the act relating to Universities and University colleges and in the Employees’ Inventions act. It is up to the employer to consider whether or not to exercise this right. The assessment is carried out by bTO on behalf of the employer.

• bTO contributes easy access to competent and relevant assistance in commercialization to researchers and employers at the research institutions in bergen.

• contact bTO if you believe you have an invention. we may ask you to fill out a Disclosure of Invention (DOFI), which will be the basis for the further commercialization process.

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Coxpit AS has developed a computerized meeting platform that can be used when multidisciplinary teams of doctors are evaluating a specific group of patients. The platform integrates within existing systems to fetch and present data nicely, and provide mechanisms for planning, organizing, evaluating previous decisions and following up meetings.

coxpit’s meeting platform solves the problem in which it filters out the significant information doctors need, and leave out information that is mostly of no interest. The meeting platform focuses on the workflow and guides the user through the program; it assists in the follow-up of the patient and will alert the team if the expected treatment is not conducted. Furthermore, it integrates with other systems, avoiding the need to log the same information several times. coxpit will be the only tool needed when running multidisciplinary meetings. coxpit has a common interface for all necessary tasks in multidisciplinary meetings, ensures timely follow up on patients, and structures the data which makes it helpful for research and quality improvement.

The initiative to start coxpit came from a thankful patient who saw an opportunity to give something back to the hospital where he was treated. as a consequence coxpit was established in 2009, and have since been working on creating a collaboration platform for doctors. The company is situated in bergen, Norway, and cooperates closely with haukeland University hospital.

www.coxpit.com

coxpit As

from left: Jo waage (Chief Medical Advisor), stian Karlsen (Head of R&D), and håkon leinan (Creative Director)Photo: Magne Sandnes

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* maria gaetana agnesi, 16 may, 1718. Italian linguist, mathematician, and phi-losopher. credited with writing the first book discussing both differential and integral calculus. The first important woman mathematician since hypatia.

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“DST geomag” is a new invention consisting of a type of data storage tag that will be used as a trip recorder or “black box” for fish, based on measure-ments of the Earth’s magnetic field.

The tags will be used on fish, and through measurements it can be possible to find its positions. This will be implemented by measuring pressure, temperature, spatial orientation in two axes and magnetic field values in three axes. The magnetic field values are calibrated in a known magnetic field (e.g. generated by a set of suitable coils) under varying controlled temperature conditions. The geographical position (and thus the location of the tag on the earth’s surface) can be achieved by comparing the magnetic measurement from the tag with data derived from global magnetic field models. Due to its small size “DsT magnetic” can be used with fish from only 30cm length onwards.

This new invention is jointly developed by researcher Dr. hans hagen stockhausen at the Institute of marine research (bergen, Norway), and enigineers at star-Oddi in reykjavik, Iceland.

The complimentary knowledge in this project; with engineering expertise in r&D of measuring instruments at star-Oddi, and the geophysical background knowledge of how to yield geographical position from a geomagnetic measurement at Imr has now resulted in a product that is ready for the market. Target group for the “DsT geomag” is first and foremost the field of marine biology, but it is applicable for any areas where monitoring of magnetic fields is needed.

dst geoMAg

reporTing Your invenTion To BTo

whaT Is a DIsclOsUrE OF INvENTION? a Disclosure of Invention (DOFI) is a description of your invention or development.

whEN TO sUbmIT a DOFI TO bTO? we recommend that you report your invention whenever you have discovered something unique with potential commercial value. If you decide to postpone your report pending further test results, there is always a risk that somebody else may claim the idea. In that case, you might lose the opportunity to commercialize your invention.

• bTO has the competence, experience and network necessary to advise you on the best strategic moment to start a process of commercialization.

• bTO handles all reports confidentially.

whO shOUlD rEPOrT? any full-time or part-time academic staff, PhD candidates, and technical-administrative staff employed at bTO’s owners and collaborators.

hOw TO rEPOrT:

• complete and submit a DOFI. The form is available at www.bergento.no.

• contact bTO by e-mail, phone or deliver the form directly to our office.

dr. hans hagen stockhausen

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* blaise Pascal, 19 June, 1623. French mathematician, physicist, and religious philosopher. Known for inventing calculating machine, Pascal’s triangle, Pascal’s law.

proTecTing The invenTion

shOUlD ThE INvENTION bE PaTENTED? If the invention or idea can be described as a practical solution to a technical problem, patenting may be an option. In order to obtain a patent the invention must be new, differ significantly from previous technology in the area, and be reproducible. as owner of the patent you will have exclusive rights to exploit your invention commercially for a limited period of time, normally 20 years, as long as the annual fee for the patent is paid.

why PrOTEcT INTEllEcTUal PrOPErTy ThrOUgh PaTENTINg? Potential commercialization partners often require patent protection to protect the investment required to bring the technology to market. bTO carefully reviews the commercial potential before investing in the patent process. It is important to be aware that patenting can be an expensive and lengthy process. The formulation of the application and the timing of the application process could also influence the costs.

• bTO will assist you regarding all questions concerning patenting and commercialization. we employ external resources with extensive experience in writing patent applications from research environments. Patent applications are always prepared in close collaboration between the researcher, bTO and a patent attorney.

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Researchers at Haukeland University Hospital have developed a new diagnostic and prognostic tool for estimating an individual patient’s risk of cancer survival and recurrence. The invention will make the decision easier for medical practitioners to provide patients suffering from cancer with a more appropriated treatment.

by a single genetic test that is highly reliable and predictive we can enable earlier disease determination so that the best treatment can be administered at an early stage. The test enables the clinicians to distinguish patients most likely to benefit from therapy from patients that would not (and avoid the severe associated risks). In addition, predictive factors may identify the appropriate therapy for an individual patient.

The invention is suitable as a diagnostic and prognostic tool for leukaemia and breast cancer, with possible applications in several other areas: colon, prostate, melanoma, thyroid, lung, and cervical.

The development of the tool is based on the discovery of the gene rINF being involved in the diagnostic/ prognostic of breast cancer. The rINF-gene is not only deregulated in malignant tissues compared to their normal tissues of origin but, importantly, high expression levels of this gene correlate to a poor overall survival in breast cancer and certain leukaemia subtypes. The prognostic test is firmly based on a specific and quantitative detection method of this novel gene at the mrNa level.

bioMArKer of cAncer

From left: Professor Johan Lillehaug, researcher, Thomas Aloysiusand Frederic Pendino, researcher (PhD, CR2)

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* gerhard henrik armauer hansen, 29 July 1841. Physician from bergen, identified the bacterium mycobacterium leprae in 1873 as the causative agent of leprosy.

paTenTing and puBLiShing

PrOTEcTINg ThE cOmmErcIal valUE OF yOUr INTEllEcTUal PrOPErTy. as a researcher you are free to publish your results at any time. but if you consider patenting the invention, you must not make your invention public before the patent application is filed.

PaTENTINg aND PUblIshINg caN bE cOOrDINaTED. Patenting your idea before you publish it, need not cause a significant delay in the publication process. however, it is crucial that everything is done in the right order. If you publish your research results before filing a patent application, you will ruin your chances of obtaining a patent. The Us has a different system; contact bTO for information.

• bTO’s aim is to complete the commercialization process without delaying your academic publication.

It may take years before a patent is granted. During this period you are free to publish the contents of the patent application. If you develop new or additional knowledge concerning your invention during this period, you should consider adding this to your application. you may add more detailed information within 12 months of the application filing date; completely new knowledge must be patented separately. The rules correspond to the principles mentioned above, i.e. you may not speak freely about new knowledge before it is protected through a filed patent application.

• If you consider patenting, contact bTO before publishing your research results.

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sAlMon lice trAp

A research team at the Institute of Marine Research - Howard Browman, Anne Berit Skiftesvik and David Fields - is developing an environmentally friendly approach to sea lice control that reduces infection rates. This differs from most other methods, which are based on removing parasites that have already settled on the fish.

The salmon louse is a copepod parasite that infects atlantic salmon. Efforts to control sea lice have focussed on chemical delousing agents and/or co-culture with cleaner fish. however, chemical treatment is rapidly becoming less effective because sea lice have developed resistance to the chemicals. There is also concern over possible adverse environmental impacts of chemical treatment. although the use of cleaner fish to control sea lice is promising, the size of wild populations is insufficient to support demand and intensive culture of these fishes is in its infancy. For all of these reasons, there is a need for alternative approaches to control sea lice infestation of both farmed and wild fish.

The approach is analogous to previously proposed sensory cue solutions. The sensory cues that the pest uses to locate its host are identified and then used in a device that creates a large false-host target that lures the pest away from the real host. browman, skiftesvik and Fields have identified the key host-specific sensory cues that attract the salmon louse to its host. That information has been used to design simple and inexpensive prototype traps that have successfully captured the free-swimming stages of sea lice. The concept is to deploy large numbers of traps around sea farms (or sea runs of wild salmon) to remove lice from the water column, leaving fewer of them to infect fish.

From left: Howard Browman and Anne Berit SkiftesvikDavid Fields was not present when picture was taken

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keYS To proTecTing Your inTeLLecTuaL properTY

Intellectual Property rights (IPr) is a broad term that comprises different kinds of legal protection of ideas, inventions, characteristics etc. These forms of protection have the following in common:

• a documented protection secures your exclusive right to exploit your invention commercially.

• Ownership is clarified through licensing. when meeting with potential collaborators you may safely present technical details concerning the product without risking that other parties pick up the ideas.

• Future discussions concerning ownership are avoided.

Patenting is a kind of protection that is relevant when it comes to commercialization of research results that are a solution of a technical problem, reproducible and not previously known. Other kinds of protection are registered trademark (protects the name of your product or company, logo or slogan) and design (protects the appearance and form of a product or a part of the product). copyright protects written text, film, art of any kind and more. The originator is granted copyright by law, and registration is not necessary.

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* alexander Fleming, 6 august 1881. scottish biologist and pharmacologist, known for discovery of penicillin.

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SCORE EEG is new and unique software within EEG description. It is the first software within this field to be based on the new international standard SCORE (Standardised Computer-based Organised Reporting of EEG).

Inventor is harald aurlien, chief physician and PhD at haukeland University hospital, with speciality certification within clinical neurophysiology and neurology. he has developed the software together with Jan brøgger, physician and PhD specialising in clinical neurophysiology, and svenn Krossnes senior microsoft solutions architect at EDb consulting group.

The software is available through holberg EEg as, offering three products: scOrE Free, scOrE Intermediate, and scOrE advanced. with scOrE Free the company will have product for free to offer the market, and a version that will ease the transition to scOrE Intermediate and scOrE advanced which have far more functionalities. The software can be integrated with EEg readers and patient record file systems, and is suitable for neurophysiological laboratories were EEg is performed.

The scOrE products will make it possible to describe EEg studies in a way that ensures better quality of the assessments, better communication of results to referring physicians, and better opportunities for education and research. This will lead to better diagnosis and therefore better treatment of patients.

holberg eeg As

from left: harald Aurlien (chief physician and PhD), svenn Krossnes (senior Microsoft solutions architect), and Jan brøgger (physician and PhD)

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* abu rayhan biruni, 15 september, 973. Persian scientist and physicist, chemist, mathematician, etc. Described as the founder of Indology, the father of geodesy, and “the first anthropologist”.

conFLicT oF inTereST

cONFlIcTs OF INTErEsT (cOI) INclUDE a varIETy OF sITUaTIONs IN which an employee is faced with conflicting loyalties, and may arise when personal economic interests conflict with the duties toward the research institution.

some examples:• If a professor that is supervisor for a student owns

a company, and the research performed by the student is relevant for the company

• If your research group establishes a company based

on their research result, and the research institution/research group buys products and services from this company.

• If a faculty member recommends that a graduate student pursue research in an area that would benefit the commercialisation of a product of a company in which the faculty member has a financial interest.

generally, if a conflict situation is permitted, specific guidelines and expectations are established prior to permitting the activity or financial interest. most conflict situations that are of concern and allowable under the law can be handled through disclosure and the setting of appropriate conditions and monitoring requirements.

• bTO takes this problem seriously, and we have a proactive, professional approach to identify and handle potential cOI’s in our portfolio.

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Professor Olav Tenstad and his research group at Department of Biomedicine, University of Bergen have developed probes for molecular imaging of renal function with MRI as well as with PET (Positron Emission Tomography).

PET is a modern non-invasive diagnostic scanning technique that provides researchers and clinicians with three-dimensional visual images of organ function. The novel probes are highly specific for functional nephrons which filter plasma, remove waste from the blood, regulate the amount of salt and water in the body and control long term blood pressure.

The technology can visualize as well as quantify glomerular filtration rate (gFr) in individual nephrones in the renal cortex important for early disease detection and prevention of renal failure in a large patient population.

since the probes are rapidly and exclusively up-concentrated in functional nephrons, the dose can be reduced by a factor of more than 100 as compared to conventional contrast agents. Potential side effects are also minimized by utilizing endogenous polypeptides already present in human body fluids.

The discovery is important since the correct and timely measurements of gFr are essential for optimal treatment and prophylaxis of a large population of patients with kidney diseases. Until now, no satisfactory non-invasive method to measure local gFr has existed.

The purpose of the project is to present the first method for gFr imaging reedy for in-human trials at the PET center, haukeland University hospital, by utilizing a non toxic endogenous marker.

iMAging of renAl function

Pet-Ct scans showing glomerular filtration after occlusion of the inferior branch of the left renal artery in an anesthetized pig. there is, as expected, a sharp and total loss of local gFr (represented by color intensity) in the inferior part of the left kidney.

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25 26 27 28 29 30 31* Fridtjof wedel-Jarlsberg Nansen, 10. October 1861. Norwegian explorer, scientist and diplomat. awarded the Nobel Peace Prize in 1922 for his work as a league of Nations high commissioner.

MaTeriaL TranSFer agreeMenT

maTErIal TraNsFEr agrEEmENTs (mTa) are agreements which regulate the physical transfer of research material between two institutions, where the intention of the receiver is to make use of the material in his own research.

an mTa regulates the rights and duties that are imposed on the sender and receiver of such material, and possible elaborations and diversions of this. The most common transfer is the transfer of biological material, such as the transfer of cell lines, reagents and vectors. mTa’s can also be used for the transfer of other material, for instance chemical components and even some kinds of software.

It is important that you contact and consult bTO if you are going to enter an mTa, as these agreements will often lay down guidelines and restrictions on the rights to future commercial exploitation of the research results. bTO can, in collaboration with the right authority at your employer’s, help negotiate terms of agreement that restrict these possibilities as little as possible.

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MAREC is a provider of advanced software for marine acoustics data. The software is developed by Christian Michelsen Research (CMR) in close collaboration with the Institute of Marine Reseach. MAREC offers two software packages for improving marine resource management:

lsss — The Large Scale Survey System — is a system for regular monitoring and analysis of a nation’s stock of different species. lsss is delivered on commercial terms with related services for training, installation, and support/maintenance. at the moment, lsss has more than 100 registered users in 8 countries.

sEaT — The School Exploration and Analysis Tool —is a decision-support system intended for large fishery vessels. sEaT is currently a research prototype and includes functionality for automatic school detection and automatic species identification. The goal of sEaT is to aid the owners of the fishery vessels to improve their business and make it easier to comply with laws and regulations.

lsss and sEaT is based upon the use of multi-frequency data.

The vision for marEc is to reach “holistic understanding of marine ecosystems”. To date, it is possible to get partial information about some marine species from acoustic data. In the future, holistic understanding of marine ecosystems will be essential in order to achieve sustainable management and harvesting of marine resources. New innovative software, taking full advantage of modern echosounders and sonars, is the key to fulfill this vision.

MArec

olav rune godø (IMR), rolf Korneliussen (IMR), ola Kristofer Øye (CMR), inge Kristian eliassen (CMR), and yngve heggelund (CMR),

mareC is currently a business unit at Cmr. For more information, see www.marec.no

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* marie curie, 7 November 1867. Physicist and chemist of Polish upbringing and, subsequently, French citizenship. Known for discovery of radium and polonium, and theory of radioactivity. Nobel Prize in Physics (1903), and in chemistry (1911).

opporTuniTieS aT BTo

bTO is located in the vilvite science discovery centre at marineholmen Technology Park, together with other commercialization actors. In addition to being part of a unique work environment for innovation, bTO offers good working conditions, intellectually challenging projects and a friendly work environment.

• as a growing company, bTO is looking for talented people who have the right expertise and a good business understanding. If you believe you are qualified, and have a specialty within an academic field of study, we hope you will write an application to us.

• students with an interest in business development, strategic marketing efforts, or design study are also encouraged to apply.

Please send an open application to: [email protected].

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There are many good helpers in the innovation value chain in the Bergen region. BTO and our projects are benefitting from all these valuable resources every day. Due to our high dealflow from the medical departments at our institutions, we have experienced a need for an incubator for young ventures within the biomedical field.

The existing and excellent incubator - Nyskapingsparken did not have sufficient funding for setting up such specialised incubator. about October 2009, the bTO board decided to allocate some of bTO’s own resources, and the University invested in facilities, to make sure that the region would get a biomedical incubator.

From 1.1.2011 the bergen biomedical Incubator is up and running at bbb - the building for basic biological research at haukeland University hospital, and its first tenant is bergenbio as. This is a good transparent way of making it possible for new ventures to make use of available capacity at the impressive scientific and technical infrastructures at the medical institution.

Our dream is that this initiative will accelerate the creation of new jobs for very skilled and highly educated people and to get new products and processes into use - faster.

the bergen bioMedicAl incubAtor

“the establishment of the bergen biomedical incubator is a positive and welcome contribution to the innovation chain that has been established by bto in recent years as part of the university’s duty to contribute to the benefit of society. For the inventors and the department of biomedicine, the establishment enables that the further development of ideas with commercial potential stemming from basic research, actually can and will take place locally.

the location within the building for basic biological research, but separate from the department, emphasizes that the incubator and commercialisation is an activity that occurs in close contact with but yet with a different focus than the basic research on the premises. Last, but not least it visualizes alternative and broader options for both the researchers and the students.”

Rolf K. Reed, Head of the Department of Biomedicine, UiB

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2011Calendar

* AdaLovelace,10December1815.British,homeschooledinmathematicsandscience.KnownfordescriptionofCharlesBabbage’searlymechanicalgeneral-purposecomputer.Appreciatedasthe“firstprogrammer”.

region Bergen generating futureS

Thereareabout4000researchersinBergenperformingresearchforcloseto4MRDNorwegiankronereachyear.Anumberofinterestingandsuccessfulenterpriseshaveemergedfromthedifferentresearchinstitutions.Theposteraboveshowsabroadrangeofspin-offcompaniesstemmingfromtheresearchinstitutionsinBergen,includingthespin-offsestablishedbyBTO.Severalofthesecompanieshavealreadymadeanimpactontheregionbyprovidingjobsandopportunitiesforexistingbusinesses,andcreatevaluebacktotheinstitutions.Andsomeofthemhaverecentlyconcludedmajorinternationaldeals,andareontheedgeofbecominglargeinternationalenterprises.Today,severalinnovativetechnologiesareinthepipelineoralreadyavailableforlicensing.

BTOpromisetodoourshareoftheeffortneededinordertoachievethegoaloftheambitiousstrategicbusinessplanfortheBergenRegion–tomaketheBergenregionadynamicgrowthandleadingknowledgeregionwithintheareaswheretheregionhasitsstrengths.

• AspartoftheRegionBergen,welookforwardtocontinueandimproveourcollaborationwiththeregionalbusinesspartners,andtoworkwithpresentandfutureresearcherswithinnovativeideas.Webelievethatthecloserwegettheindustryandresearchinstitutionstoworktogether,themorecommercialopportunitieswillcomeourway.

• AtBTOwebelievethatmostoftheworld’sgreatideashaveyettobeputintolife.Haveyougotanidea?

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