Brown Blue Black
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口腔診斷學
陳玉昆教授 : 高雄醫學大學 口腔病理科
07-3121101~2755
Intraoral brown, bluish and blak
onditions口腔棕色、藍色、黑色疾病
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!nderstandin":1. #i$$erential dia"nosis o$ intraoral brown,
bluish and blak onditions
學 習 目 標
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1. %aohsiun" &edial !ni'ersity, (ral )atholo"y #e*artment2. +awson : (ral #iseases. 3rd d., **. 11.2-11.10
3. +awson : (ral #iseases. 3rd d., **. 11.12
/. +awson : (ral #iseases. 3rd d., **. 11.13
5. I) merian air-$ore institute o$ *atholo"y
e$erenes:
參考資料
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&elanin
lood
e$. 1
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4airy
ton"ue
oali6ed
*i"mented
ndorine
disorder
rownish, lakish
)i"mented esions
o"enous ndo"enous
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e$. 2
Intraoral brown and blak onditions
8yrosinase
dihydroy*henylalanine)
8yrosine #() &elanin
&elanoyte 9timulatin" 4ormone
http://smb//upload.wikimedia.org/wikipedia/commons/c/cf/3%2C4-Dihydroxy-L-phenylalanin_%28Levodopa%29.svg
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Intraoral brown and blak onditionsormal enti"o sim*le ;untional ati'ity
+om*ound ne'us Intramuosal ne'us lue ne'us
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;untional ati'ity
Intramuosal ne'us
+om*ound ne'usIntraoral +utaneous
amina
*ro*ria
e$s. 1, 2
Intraoral brown and blak onditions
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*ithelium
)i"mented
basalell
&elano*ha"e
)i"mentedbasal
keratinoyte
e$s. 1, 2
Intraoral brown and blak onditions
(ral &elanoti &aule
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mal"am restoration
mal"am retro"rade $illin"
e$s. 1, 3
Intraoral brown and blak onditions
I t l b d bl k diti
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4airy 8on"ue
e$. 1
Intraoral brown and blak onditions
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arly +han"es o$ &elanoma1. **ear reently
2. +han"e in de"ree o$ *i"mentation
3. leedin" or uleration/. a*id "rowth in si6e or ele'ated
e$s. 1, 2
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&elanoma
e$. 1
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&elanoma
e$. 1
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&elanoma
e$. 1
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&elanoma
e$. 1
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&elanoma
e$. 1
Immunohistochemical staining of HMB-45 (A) and S-100 (B) revealed diffuseositivit! in the tumor cells"
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=on elin"hausen>s disease o$ skin
multi*le neuro$ibroma
+a$a-u-ait-s*ot
e$. 5
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+a$a-u-ait-s*ot
e$. 1
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ddison>s #isease
)ituitary
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)eut6-;e"hers 9yndrome
luish blak maules
9kin *i"ment not oral tends $ade with a"e
Intestinal
*oly*
e$. 1
l i h i
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4eman"ioma &uoele
ru*tion yst4ematoma
luish esions
e$. 1
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=arioses
e$. 1
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&uoe*idermoid +arinoma
e$. 1
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Knowing how to differentiatebrown, bluish & black
oral conditions
9!&&?
