BRL Biotechnology Research Laboratories

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Honours 2010 BRL Biotechnology Research Laboratories Vaccines Biotechnology Immunity Innate Immunity Parasite biology Asthma/ Allergy RL – Biotechnology Research Laboratori RL – Biotechnology Research Laboratori

description

BRL Biotechnology Research Laboratories. BRL – Biotechnology Research Laboratories. Parasite biology. Vaccines Biotechnology Immunity. Innate Immunity. Asthma/ Allergy. BRL Biotechnology Research Laboratories. Parasite Biology. Dr David Piedrafita. Nematode and Helminth parasites. - PowerPoint PPT Presentation

Transcript of BRL Biotechnology Research Laboratories

Page 1: BRL Biotechnology Research Laboratories

Honours 2010

BRLBiotechnology Research Laboratories

VaccinesBiotechnology

ImmunityInnate

Immunity

Parasitebiology

Asthma/Allergy

BRL – Biotechnology Research LaboratoriesBRL – Biotechnology Research Laboratories

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Honours 2010

Parasite Biology

BRLBiotechnology Research Laboratories

Dr David Piedrafita

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Honours 2010

Nematode and Helminth parasitesNematode and Helminth parasites

SchistosomeHaemonchus Fasciola

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Honours 2010

Demands for Livestock productsDemands for Livestock products

Parasites most economically important worldwide

050

100150200250300350400

Mil metric tons

Meat milk meat milk

Developed Developing

Global Meat and milk consumption

198319932020

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Honours 2010

Honours projectsHonours projects

Parasite biochemistry and molecular Parasite biochemistry and molecular biology - proteasesbiology - proteases

Host resistanceHost resistance

Identify and trial vaccine candidatesIdentify and trial vaccine candidates

Parasite BiologyParasite Biology

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Mechanisms underlying Mechanisms underlying asthma and allergyasthma and allergy

Dr Rob Bischof Prof Els MeeusenDr Stuart Hirst Dr Tim Moss

BRLBiotechnology Research Laboratories

Rob Bischof

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Honours 2009

Asthma and AllergyAsthma and Allergy

Asthma and allergies – vaccinationAsthma and allergies – vaccination

Airway mucosa – GalectinsAirway mucosa – Galectins

What initiates asthma/allergy.What initiates asthma/allergy.

Honours ProjectsHonours Projects

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Honours 2010

Innate Immunity in Vaccination and Allergy

BRLBiotechnology Research Laboratories

Dr Mike de Veer*

* Image may not necessarily be Mike de Veer...just resemble him

Lymphatic Cannulation

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Lymphatic transportLymphatic transport

Allergy Vaccination

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Honours 2010

Innate ImmunityInnate Immunity

Adjuvant optimisation – vaccinationAdjuvant optimisation – vaccination

Lymph physiology and immunologyLymph physiology and immunology

What initiates immune responses.What initiates immune responses.

Honours ProjectsHonours Projects

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Honours 2010

What can you learn?What can you learn?

Cell Biology

Cycle403938373635343332313029282726252423222120191817161514131211109876543210

Flu

ores

cenc

e (n

orm

)

1

10

100

1000

Threshold: 52 (Adjusted manually)

Baseline settings: automatic, Drift correction OFF

Molecular Biology

Proteomics/Bioinformatics

Adjuvant effects on anti-OVA sera antibodies

Salin

eM

PLAlu

m

0

20000

40000

60000

Adjuvant

Sea

r aO

VA

tit

re

Vaccinology

ImmunologyPhysiology

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Honours 2010

Diverse projects

Basic science with a commercial outlook

Good Science in a friendly environment

ABRLAnimal Biotechnology Research Laboratories

Thank you