BRENDA Tutorial · BRENDA Chemical structure of vanillic acid - Mozilla Fir BRENDA vanillic acid...
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BRENDA Tutorial Ligand Search
Transcript of BRENDA Tutorial · BRENDA Chemical structure of vanillic acid - Mozilla Fir BRENDA vanillic acid...
BRENDA TutorialLigand Search
How to find ligands / metabolites such assubstrates, products, inhibitors etc.
Substances interacting with enzymes
Enter the ligand name ora part of it and performthe search
Choose „Ligands“ to display theenzyme-related information on vanillic acid
The result page shows all enzymesinteracting with the ligand, including
their derivatives, and their roles
you can displaythe molecularstructure
On the next page you getbasic information on theLigand Summary Page with…
…more detailed informationon the structure, synonyms, and their roles in theenzyme-ligand interaction, enzyme kinetic parameters, and references in BRENDA
you can directly switch to the„Substructure Search“ to find
similar ligands interacting withenzymes in BRENDA
On the result page all ligandsstructurally similar to the
searched ligand are displayed
If you find an appropriateligand, you can perform a search in BRENDA to getmore information
On the result page youfind further details ofthe searched ligand
Otherwise you could perform a new Substructure Search by
drawing the molceular structurewith the editor and choosingappropriate search options.
