Books Received

Academic Environment. A Handbook for Evaluat-ing Faculty Employment Opportunities. Karl W. Lanks.Faculty Press, Brooklyn, NY, 1990. vi, 127 pp., illus.Paper, $12.95.

Acid-Base Catalysis. Kozo Tanabe et al., Eds.Kodansha, Tokyo, and VCH, New York, 1989. xx, 532pp., illus. $140. From a symposium, Sapporo, Japan,.Nov. 1988.

Angewandte Lineare Algebra. Bertram Huppert.De Gruyter, Hawthorne, NY, 1990. viii, 646 pp., ilus.

$307.Antiproton-Nucleon and Antiproton-Nucleus In-

teractions. F. Bradamante, J.-M. Richard, and R.Klapisch, Eds. Plenum, New York, 1990. x, 331 pp.,illus. $69.50. Ettore Majorana International ScienceSeries, vol. 47. From a course, Erice, Italy, June 1988.

Artificial Intelligence in Process Engineering.Michael L. Mavrovouniotis, Ed. Academic Press, SanDiego, CA, 1990. xiv, 367 pp., illus. $49.95.At the Heart of the Bomb. The Dangerous Allure of

Weapons Work. Debra Rosenthal. Addison-Wesley,Reading, MA, 1990. xii, 244 pp. $18.95.Auditory Scene Analysis. The Perceptual Organi-

zation of Sound. Albert S. Bregman. MIT Press, Cam-bridge, MA, 1990. xvi, 773 pp., illus. $55. A BradfordBook.

Biotechnology and Human Genetic Predisposi-tion to Disease. Charles R. Cantor et al., Eds. Wiley-Liss, New York, 1990. xviii, 241 pp., illus. $75. UCLASymposia on Molecular and Cellular Biology, New Se-ries, vol. 126. From a symposium, Steamboat Springs,CO, March 1989.Biotechnology, Microbes and the Environment.

Steven C. Witt. Center for Science Information, SanFrancisco, 1990. vi, 219 pp., illus. Paper, $17.95. ABriefbook.

Britain and the Cold War. 1945 as GeopoliticalTransition. Peter J. Taylor. Pinter, London, and Guil-ford, New York, 1990. xiv, 153 pp., illus. $30. Geogra-phy and Intemational Relations Series.

The Buming Season. The Murder of Chico Mendesand the Fight for the Amazon Rain Forest. AndrewRevkin. Houghton Mifflin, Boston, 1990. xiv, 317 pp.,+ plates. $19.95.The Business of Breeding. Hybrid Corn in Illi-

nois, 1890-1940. Deborah Fitzgerald. Cornell Univer-sity Press, Ithaca, NY, 1990. xiv, 248 pp., illus. $29.95.The Cambridge Illustrated Dictionary of Natural

History. R. J. Lincoln and G. A. Boxshall. Illustrationsby Roberta Smith. Cambridge University Press, NewYork, 1990. iv, 413 pp. Paper, $14.95. Reprint, 1987ed.

Cell Volume Regulation. Klaus W. Beyenbach, Ed.Karger, New York, 1990. viii, 166 pp., illus. $99.50.Comparative Physiology, vol. 4.

Cellular and Molecular Biology of Normal andAbnormal. Erythroid Membranes. Carl M. Cohen andJiri Palek, Eds. Wiley-Liss, New York, 1990. xviii, 339pp., illus. $99. UCLA Symposia on Molecular andCellular Biology New Series, vol. 118. From a sympo-sium, Taos, N-, Feb. 1989.A Centennial Review. S. Richard Silverman and

Patricia B. Kricos, Eds. Alexander Graham Bell Associa-tion for the Deaf, Washington, DC, 1990. iv, 103 pp.,illus. Paper, $9.95. Volta Review, vol. 92, no. 4.CERN Accelerator School Third Advanced Ac-

celerator Physics Course. (Uppsala, Sweden, Sept.1989.) S. Turner, Ed. European Organization for Nu-clear Research, Geneva, 1990. x, 218 pp., illus. Paper.Chemical Analysis of Ecological Materials. Stew-

art E. Allen, Ed. 2nd ed. Blackwell Scientific, Boston,1990. xii, 368 pp., illus. $99.95.The Chemistry of Metal Cluster Complexes. Du-

ward F. Shriver, Herbert D. Kaesz, and Richard D.Adams, Eds. VCH, New York, 1990. viii, 439 pp., illus.$85.

Children at Risk. An Evaluation of Factors Contrib-uting to Child Abuse and Neglect. Robert T. Ammer-man and Michel Hersen, Eds. Plenum, New York, 1990.xviii, 314 pp. $43.Chiamydlal Infections. William R. Bowie et al., Eds.

Cambridge University Press, New York, 1990. xxii, 602pp., illus. $80. From a symposium, Harrison HotSprings, BC, Canada, June 1990.Computational Chemical Graph Theory. Dcnnis

H. Rouvray, Ed. Nova, Commack, NY, 1990. iv, 331illus. $72. From a symposium, Los Angeles, Sept.

Conservation in Africa. People, Policies and Prac-tice. David Anderson and Richard Grove, Eds. Cam-

bridge University Press, New York, 1990. x, 355 pp.illus. Paper, $34.50. Based on a workshop, Carnbridge,U.K., April 1985. Reprint, 1987 ed.Control of Virus Diseases. N. J. Dimmock, P. D.

Griffiths, and C. R. Madeley, Eds. Cambridge UniversityPress, New York, 1990. x, 373 pp., illus. $85. Symposiaof the Society for General Microbiology, 45.

Data Quality in Longitudinal Research. DavidMagnusson and Lars R. Bergman, Eds. CambridgeUniversity Press, New York, 1990. xii, 285 pp., illus.$54.50. European Network on Longitudinal Studies onIndividual Development. From a workshop, Ronne-berga, Stockholm, Dec. 1987.Dawn of the Age of Mammals in the Northern

Part of the RockyMountain Interior, North America.Thomas M. Brown and Kenneth D. Rose, Eds. Geolog-ical Society of America, Boulder, CO, 1990. x, 241 pp.,illus. Paper, $45. GSA Special Paper 243.Enjoying a Life in Science. The Autobiography of

P. F. Scholander. University of Alaska Press, Fairbanks,1990. xii, 226 pp., illus. $22.95.Environmental Data Report. Prepared for United

Nations Environment Programme by GEMS Monitor-ing and Assessment Research Centre, London, in coop-eration with the World Resources Institute, Washington,DC. 2nd ed. Basil Blackweli, Cambridge, MA, 1990. viii,547 pp., illus. Paper, $39.95.Environmental Injury to Plants. Frank Katterman,

Ed. Academic Press, San Diego, CA, 1990. xii, 290 pp.,illus. $50. From a symposium, Toronto, June 1988.Environments at Risk. Case Histories of Impact

Assessment. Derek Ellis. Springer-Verlag, New York,1990. xiv, 329 pp., illus. Paper, $39.50.Enzymes in Industry. Production and Applications.

Wolfgang Gerhartz, Ed. VCH, New York, 1990. xviii,321 pp., illus. $85.

Essential Cell Biology. Christopher C. Widnell andKarl H. Pfenninger, Eds. Williams and Wilkins, Balti-more, MD, 1990. xii, 396 pp., illus. Paper, $33.95.European Neogene Mammal Chronology. Everett

H. Lindsay, Volker Fahlbusch, and Pierre Mein, Eds.Plenum, New York, 1990. x, 658 pp., illus. $125.NATO Advanced Science Institutes Series A, vol. 180.

Evolution and the Myth of Creationism. A BasicGuide to the Facts in the Evolution Debate. Tim M.Berra. Stanford University Press, Stanford, CA, 1990.xxii, 198 pp., illus. $29.50; paper, $7.95.

Fear and Defence. Pauf F. Brian et al., Eds. Har-wood, New York, 1990. x, 420 pp., illus. $89. EttoreMajorana International Life Sciences Series, vol. 8. Froma course, Erice, Italy, Oct. 1988.

Forest Regulation, Harvest Scheduling, andPlanning Techniques. William A. Leuschner. Wiley-Interscience, New York, 1990. xiv, 281 pp., illus.$49.95.Foundation for the Future. The ABM Treaty and

National Security. Matthew Bunn. The Arms ControlAssociation, Washington, DC, 1990. viii, 222 pp., illus.Paper, $20.Phe Fourth Way. A Theory ofKnowledge. Reinhardt

Grossman, Indiana University Press, Bloomington,1990. viii, 312 pp., illus. $35.Gauge Invariance. T. P. Cheng and Ling-Fong Li,

Eds. American Association of Physics Teachers, CollegePark, MD, 1990. iv, 105 pp., illus. Paper, $16.Geomicrobiology. Henry Lutz Ehrlich. 2nd ed. Dek-

ker, New York, 1990. xvi, 646 pp., illus. $135.Global Freshwater Quality. A First Assessment.

Michel Meybeck, Deborah V. Chapman, and RichardHelmer, Eds. Basil Blackwell Reference, Cambridge,MA, 1990. xii, 306 pp., illus. Paper, $64.95. GlobalEnvironment Monitoring System. World Health Orga-nization. United Nations Environment Programme.The Grand Unified Theory. Randell L. Mills and

John J. Farrell. Mills Technologies, Cochranville, PA,1990. vi, 140 pp., illus. $25.Gravitation. SL (2, C) Gauge Theory and Conserva-

tion Laws. M. Carmeli, E. Leibowitz, and N. Nissani.World Scientific, Teaneck, NJ, 1990. xiv, 102 pp. $24.

Habilitation Planning for Aduits with Disabilities.Robert I. Schalock and William E. Kiernan. Springer-Verlag, New York, 1990. xii, 233 pp., illus. $59. Disor-ders of Human Learning, Behavior, and Communica-tion.Handbook of Chemical Property Estimation

Methods. Environmental Behavior of Organic Com-pounds. Warren J. Lyman, William F. Reeh[, and DavidH. Rosenblatt, Eds. American Chemical Society, Wash-ington, DC, 1990. Variously paged, illus. $49.95. Re-print, 1982 ed.The Human Carer. The Self in the Symbolic World.

Walter Goldschmidt. Basil Blackwell, Cambridge, MA,1990. xii, 285 pp. $36.95.

Immunology. Clinical, Fundamental, and Therapeu-tic Aspects. Bhanu P. Ram, Mary C. Harris, and PraveenTyle, Eds. VCH, New York, 1990. xii, 364 pp., illus.$75. Immunology, Biochemistry, and Biotechnology,vol. 1.

Impact of Carbon Dioxide, Trace Gases, andClimate Change on Global Agriculture. Bruce A.Kimball, Norman J. Rosenberg, and Leon HartwellAllen, Jr., Eds. American Society of Agronomy, CropScience Society of America, and Soil Science Society ofAmerica, Madison, WI, 1990. xviii, 133 pp., illus. Paper,$15. ASA Special Publication no. 53. From a sympo-sium, Anaheim, CA, Dec. 1988.

Information and Organizations. Arthur L. Stinch-combe. University of California Press, Berkeley, 1990.xii, 391 pp., illus. $45; paper, $13.95. California Serieson Social Choice and Political Economy, 19.

Inositol Metabolism In Plants. D. James Morre,Wendy F. Boss, and Frank A. Loewus, Eds. Wiley-Liss,New York, 1990. xviii, 393 pp., illus. $96. Plant Biol-ogy, vol. 9. Based on a workshop, West Lafayette, IN,April 1988.Measures of Complexity and Chaos. Neal B. Abra-

ham et al., Eds. Plenum, New York, 1990. x, 476 pp.,illus. $105. NATO Advanced Science Institutes Series B,vol. 208. From a workshop, Bryn Mawr, PA, June 1989.Mechanisms of Forest Response to Acidic Dep-

osition. Alan A. Lucier and Sharon G. Haines, Eds.Springer-Verlag, New York, 1990. x, 245 pp., illus. $49.The Medicine Men. Oglala Sioux Ceremony and

Healing. Thomas H. Lewis. Published in cooperationwith the American Indian Studies Research Institute,Indiana University, by University of Nebraska Press,Lincoln, 1990. viii, 219 pp., illus. $19.95. Studies in theAnthropology of North American Indians.

NutrItion olicy for Food-Rich Countries. A Stra-tegic Analysis. Nancy Milo. Johns Hopkins UniversityPress, Baltimore, 1990. xii, 224 pp. $39.95.

Optical Computing in Japan. S. Ishihara, Ed. Nova,Commack, NY, 1990. x, 525 pp., illus. $98.

Orca. The Whale Called Killer. Erich Hoyt. 3rd ed.Camden, Charlotte, VT, 1990. 291 pp., illus., + plates.Paper, $12.95.Organic Chemistry of the Earth's Atmosphere.

Valerii A. Isidorov. Springer-Verlag, New York, 1990. x,215 pp., illus. $98. Translated from the Russian editionby E. A. Koroleva.Peerless Science. Peer Review and U.S. Science

Policy. Daryl E. Chubin and Edward J. Hackett. StateUniversity of New York Press, Albany, 1990. xiv, 267pp. $49.50; paper, $16.95. SUNY Series in Science,Technology, and Society.

Pesticides and Non-Target Invertebrates. Paul C.Jepson, Ed. Intercept, Wimborne, U.K., 1989 (distrib-utor, VCH, New York). xiv, 240 pp., ilus. $75.Phosphate Deposits of the World. Vol. 3, Neogene

to Modem Phosphorites. William C. Burnett and StanleyR. Riggs, Eds. Cambridge University Press, New York,1990. xvi, 464 pp., illus. $140. International GeologicalCorrelation Programme Project 156: Phosphorites.Rockets into Space. Frank H. Winter. Harvard

University Press, Cambridge, MA, 1990. xiv, 165 pp.,illus. $22.50. Frontiers of Space.The Roots of Evil. The Origins of Genocide and

Other Group Violence. Ervin Staub. Cambridge Univer-sity Press, New York, 1990. xvi, 336 pp. $29.95.The Samoa Reader. Anthropologists Take Stock.

Hiram Caton, Ed. University Press ofAmerica, Lanham,MD, 1990. xiv, 351 pp. $38.75; paper, $22.75.

Satellite Remote %ensing for Hydrology and Wa-ter Management. The Mediterranean Coasts and Is-lands. Eric C. Barrett, Clare H. Power, and AntonMicallef, Eds. Gordon and Breach, New York, 1990. xiv,322 pp., illus. $134. Current Topics in Remote Sensing,vol. l. From a course, Rabat, Malta, Oct. 1988.

Sequential Analysis. A Guide for Behavioral Re-searchers. John Mordechai Gottman and Anup KumarRoy. Cambridge University Press, New York, 1990. xii,275 pp., illus. $29.95.

Shattering. Food, Politics, and the Loss of GeneticDiversity. Cary Fowler and Pat Mooney. University ofArizona Press, Tucson, 1990. xvi, 279 pp., illus. $24.95;paper, $12.95.Twistor Theory for Riemannian Symmetric

Spaces. With Applications to Harmonic Maps of Rie-mann Surfaces. Francis E. Burstall and John H. Rawns-ley. Springer-Verlag, New York, 1990. iv, 112 pp.Paper, $14.70. Lecture Notes in Mathematics, vol. 1424.Volcanism and Tectonism in the Columbia River

Flood-Basait Province. Stephen P. Reidel and Peter R.Hooper, Eds. Geological Society of America, Boulder,CO, 1990. xiv, 386 pp., illus., + map. Paper, $52.50.GSA Special Paper 239.

BOOK REVIEWS 105531 AUGUST 1990

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POSITIONS OPEN

The Department of Molecular Biology at PrincetonUniversity invites applications for a tenure-track positionat the ASSISTANT PROFESSOR level from investi-gators who use the mouse as an experimental system.Areas of specialization may include (but are not restrictedto) immunology, genetics, neurobiology, developmentalbiology, chromosome structure, or genome analysis.Candidates should have a Ph.D. degree and appropriateexperience in mouse molecular biology. Applicantsshould send curriculum vitae, a summary of researchinterests, and the names of at least three referees to:

Mouse Molecular Biology Search CommitteeDepartment of Molecular Biology

Princeton UniversityPrinceton, NJ 08544

Application deadline is 20 October 1990.Princeton University is an Equal Opportunity/Affirmative

Action Employer.

UNIVERSITY OF LOUISVILLEDEPARTMENT OF BIOLOGY

Tenure-track position to be filled for the 1991-92academic year at the ASSISTANT PROFESSOR level,Ph.D. requlred, specializing in vertebrate zoology or

closely refated field (other than ichthyology); postdoc-toral experience preferred. Research must be compatiblewith environmental biology doctoral program, prefer-ence in fields complementary to present faculty (e.g.,biodiversity, molecular systematics, behavior). Teachingresponsibilities in specialty for graduate courses and incomparative vertebrate anatomy for undergraduate cur-

riculum. Service includes curation of terrestrial vertebratecollections. Applications must be received by 1 October1990. Submit curriculum vitae, list of publications, andnames, addresses, and telephone numbers of five personsfrom whom letters of reference may be obtained. Sendto: Search Committee, Vertebrate Zoologist, Dr.William D. Pearson, Chair, Department of Biology,University of Louisville, Louisville, KY 40292.The Universty ofLouisvle is anAfirmativeAction/Equal

Opportunity Employer.

Minneapolis: The University of Minnesota Depart-ment of Psychiatry seeks psychiatrists to fill two 12-month faculty positions as ASSISTANT PROFESSORwith a probationary appointment towards tenure. Theposition entails commitment to research and teaching.The successful applicant will share with other facultymembers responsibility for one of several teams whichtreat hospitalized and nonhospitalized general psychiatricpatients. Each team, in addition to treating patients, hasthe responsibility of trainig residents, medical students,and psychology interns. The teams may develop special-ized treatment and research programs for particularpsychiatric disorders. Applicants should be Board-elisi-le, with demonstrated interest and ability to do psychi-

atric research. Send r6sumes to: Richard Pyle, M.D.,UMHC Box 393, University ofMinnesota Hospitals,Minneapolis, MN 55455 by 31 January 1991.The University of Minnesota is an Equal Opportunity

Educator and Employer and invites and encourages applicationsfrom wonen and minorities.

ASSISTANT PROFESSOR (NEUROSURGERY)Position available: assistant professor of surgery (neu-

rosurgery) for director of clinical research. Applicantsshould have Ph.D. and advanced practice nursing as anurse practitioner and/or a clinical nurse specialst. Afaculty position for a director of clinical research at theassistant professor level in the Division of NeurologicalSurgery of the Department of Surgery at the Universityof Utah School of Medicine is available. The positionrequires a Ph.D. in a nursing discipline. The appointeeshould have a strong background in neuroscience criticalcare nursing, with expertise in nutrition management ofneurologically impaired patients, and experience in de-sign management ofresearch protocols. The positionrequires advanced practice nursing abilities as a nursepractitioner and/or a clinical nurse specialist. Deadline forreceipt of applications is 15 October 1990. Applicationspostmarked or submitted after the dosing date may beconsidered ifno qualified candidates have applied by thattime. Contact: M. Peter Heilbrun, M.D., Professorand Head, Division of Neurosurgery, University ofUtah Medical Center, 50 North Medical Drive, SaltLake City, UT 84132. The University of Utah is an

Afirmative Action/Equal Opportunity Employer.

I056

POSITIONS OPEN

Yale University: The Department of Chemistry invitesapplications for an anticipated position at the ASSIST-ANT PROFESSOR level in the area of organic chem-istry, effective the academic year 1991. We seek talentedteacher-scholars who show promise for developing out-standing research programs.

Applicants should send curriculum vitae, a statementofresearch interests and plans, and should arrange for thesubmission of three letters of recommendation. All ma-terials should be received by 31 October 1990. Sendapplications to: Professor Frederick E. Ziegler, Chair-man, Department of Chemistry, 225 Prospect Street,Box 6666, Yale University, New Haven, CT 06511-8118. Yale University is an Equal Opportunity/AffinnativeAction Employer.

ASSISTANT PROFESSORS. The Department ofAnatomy is seeking applications for tenure-track assistantprofessor positions with teaching in histology/neuro-science or gross anatomy. Strong research programs areessential. Research areas are open, although preferencewill be given to candidates in neurobiology or cellular/molecular biology. Ph.D., M.D./Ph.D., or equivalentdegrees; at least 2 years of postdoctoral research; andfunded or fundable research programs are required.Submit curriculum vitae and arrange for three letters ofrecommendation to be sent by 15 October 1990 to: Dr.Joseph T. Weber, Department of Anatomy, TulaneMedical School, 1430 Tulane Avenue, New Orleans,LA 70112. Tulane is an Equal Opportunity/AfinativeAction Employer. Applicationsfrom qualtfied women and mi-norities are encouraged.

ASSISTANT PROFESSOR, NUTRITIONAL SCI-ENCES. Tenure-track, 9-month, teadcinJresearch posi-tion. Qualifications include a Ph.D. in nutrition or relatedarea, teaching experience, and research publications. Re-sponsibilities include teach two nutritional science courses,advise students, develop a fundable research program, anduniversity service. Applications accepted until 30 September1990, or until position is filled. Women and minority candidatesare encouraged to apply. The University of Vermont is anAffirmativeAction/Equal Opportunity Employer. Send letter ofapplication induding narrative statements of teaching expe-nence and research plans, names and address of three reTer-ees, curriculum vitae listing all publications, and other mate-rials considered appropriate to: Dr. Robert S. Tyzbir,Department of Nutritional Sciences, University of Ver-mont, Budrington, VT 05405.

ASSISTANT PROFESSORMOLECULAR IMMUNOLOGY

The Department of Microbiology and Immunology,Baylor College of Medicine, invites applications for atenure-track faculty position in molecuar imuWe seek an individual of exceptional capabilities with astrong postdoctoral training record and substantial re-search productivity in molecular biology and/or molecu-lar immunology. The candidate shouldbe determined toestablish a strong independent research program andshould welcome collaborative interactions with depart-ment colleagues in T lymphocyte immunoregulation,MMC structure, function, and genetics. Interested appli-cants should send curriculum vitae, a brief description ofresearch plans, and names of three references to: Dr.Robert R. Rich, Department of Microbiology andImmunology, M929, Baylor College of Medicine,Houston, TX 77030. Applications received before 31October 1990 will receive preference in review. BaylorCollge ofMedicine is an Equal Opportunity/Afirmative Ac-tion Employer.

ASSISTANT PROFESSOR OR INSTRUCTOR.Two positions available: ECOLOGIST, full- or part-time position (January to September 1991) to teach oneor two ecological and/or field oriented courses, environ-mental science for nonmajors, and to team-teach anintroductory level physiological ecology course; MI-CROBIOLOGIST, 6-month appointment (March toSeptember 1991) to teach genetics, microbiology, and toteam-teach cell biology. Ph.D. and teaching experiencepreferred for both positions. Send curriculum vitae,transcripts, and three letters of recommendation to: Dr.Carolyn R Newton, Department of Biology, Kala-mazoo Coliege, Kalamazoo, MI 49007. Review ofapplications will begin 1 October 1990 and continueuntil the positions are filled. Affirmative Action/EqualOpportunity Employer. Kalamazoo College is committed todiversity and particularly encourages women and minorities toapply.

SCIENCE, VOL. 24-9

POSITIONS OPEN

ASSISTANT PROFESSOR (PHYSIOLOGY).Utilize a variety of invasive and noninvasive biophysicaland biochemical techniques to study isolated and intactcerebral blood vessels to explore the mechanismswhereby substances of abuse can cause brain injury, inorder to design new therapeutic modalities to prevent,diagnose, and treat these brain disorders. Two years ofpostdoctoral training in cardiovascular pathophysiologywith special emphasis in biophysics and biochemistry ofcerebral vascular smooth muscle. Familiarity with atomicabsorption spectroscopy, reflectance spectroscopy, high-pressure liquid chromatography, computer program-ming, and image analysis required. Doctorate in patho-physiology, 2 years of expenence; $25,000 to $30,000per year. Immigration Service authorizatonfor emp t.AffirmativeAction Employer. Send resume in duplicate to:Dr. Burton M. Altura, Department of Physiology,Box 31, State University of New York (SUNY)Health Science Center at Brooklyn, 450 ClarksonAvenue, Brooklyn, NY 11203-2098. DMC#C0345.

ASSISTANT PROFESSOR, NEUROPHARMA-COLOGY/NEUROTOXICOLOGY. The Depart-ment of Pharmacology, Toxicology, and Therapeutics atthe University of Kansas Medical Center invites applica-tions for a tenure-track position for a neurophannacolo-

gist, neurochemist, or neurotoxicologist. The applicant

must have an appropriate Ph.D. or M.D. degree, with

two or more years of relevant postdoctoral experience.The successful candidate will be expected to establish an

independent research program and contribute to gradu-ate and medical teaching. Research interest is open buttargeted areas include drug abuse, developmental andbehavioral pharmacology/toxicology, and mechanisms ofbrain damage. Primary appointment will be in thisdepartment but will indude an affiliation with the MentalRetardation Research Center. A further affiliation withthe Center for Environmental and Occupational Healthis possible. Applications, including curriculum vitae, ashort summary of research plans, and the names of threereferences, should be received by 1 November 1990, butthe search will remain open until the position is filled.Send applications to: Dr. Richard H. Alper, Depart-ment of Pharmacology, Toxicology, and Therapeu-tics, University of Kansas Medical Center, KansasCity, KS 66103. The University ofKansas is anAjlinnativeActiotVEqual Opportunity Employer.

GENETICS, CELL AND MOLECULARBIOLOGY, AND DEVELOPMENT

DEPARTMENT OF BIOCHEMISTRYBAYLOR COLLEGE OF MIEDICINE

The Department ofBiochemistry has two tenure-trackfaculty positions in the areas of genetics, cell and molec-ular biology, and development. These positions providenewly renovated laboratory space, institutional start-upfunding, limited teaching requirements, and an excellentopeortunity to build a research program within a largeand interactive research community. Applicants at theASSISTANT PROFESSOR level are preferred, butmore senior candidates will be considered. Interestedindividuals should send their curriculum vitae, a state-ment of present and future research interests, and thenames of three references to:

Dr. John Wilson, Search CommitteeDepartment of Biochemistry

Baylor Coliege of Medicine

One Baylor Plaza

Houston, TX 77030An Equal Opportunity Employer.

ASSISTANT OR ASSOCIATE PROFESSOR;DIRECTOR, HUMAN VESTIBULAR LABORA-TORY. The Department of Surgery at the University ofChicago invites applications for a tenure-track position(assistant or associate professor), which involves direct-ing a human/dinical vestibular testing laboratory. Appli-cants should hold an M.D. or a Ph.D. degree and have anestablished track record in basic and clinical research,incuding demonstrated ability to secure extramuralfundin. Please send curriculum vitae, a summary ofresearch and clinical interests, and a list of three refer-ences by 1 October 1990 to: Vijay Dayal, M.D., Depart-ment ofSurgery, Section ofOtolaryngology/Head andNeck Surgery, 5841 South Maryland Avenue, Box412, Chicago, IL 60637. The Univerity ofCh is anAfinnativeAction/Equad Opportunity Employer.

BEHAVIORAL PHYSIOLOGISTNEUROETHOLOGIST

The Department of Biological Sciences, University ofCincinnati, has a tenure-track position in behavioralphysiology available at the ASSISTANT PROFES-SOR level sartng 1 September 1991. We seek anindividual whose primary research interests are in animalbehavior and its underlying physiological mechanisms(e.g., neural, endocrne, sensory). Preference will begiven to candidates whose research integrates cellularand/or Physiological approaches with behavioral obser-vaton andanalysis, and who can interact with depart-mental colleagues in behavioral ecology and physiolo*y.The university is a comprehensive state university with

an enrollment of 36,000 students. The department has30 faculty in diverse areas and approximately 70 graduatestudents, and is currently expanding in the areas ofenvironmental/evolutionary biology and cellular/molecu-lar biology.The position requires a Ph.D. degree, and postdoc-

toral experience is preferred. The successful candidatewill be expected to develop a vigorous, externally fundedresearch program, train graduate students, and teachgraduate and undergraduate courses in animal behaviorand/or their specialt. Applicants should submit, by 15November 1990, curriculum vitae, a description of re-search and teaching interests, and at least three letters ofreference to: Dr. George W. Uetz, Behavioral Physi-ologist Search Committee, Department of BiologicalSciences, University of Cincinnati, Cincinnat, OH45221-0006. The University of Cincinnati is an EqualOpportunity/Afinatve Action Empoyer.

PLANT GENE EXPRESSIONUNIVERSITY OF NEBRASKA-LINCOLN

Seeking applications for tenure-track ASSISTANTOR ASSOCIATE PROFESSOR position with De-partment ofBiochemistry in conjunction with Universityof Nebraskas Center for Biotechnology. Particularlyinterested in candidates conducting research in plantgene expression (e.g., identification and characterization

ofgenes and gene products that regulate gene exprpssion,developmental aspects of gene regulation, regulation ofgenes involved in photosynthesis and/or cellular growthand metabolism). ()ther areas ofplant molecular biologymay also be considered. Successful a plicant will be

expected to develop a strong program and

participate in teaching at the undergraduate and/or grad-uate levels beginning 2 years after initial appointment.Position is joint appointment between Center for Bio-technology and Institute of Agriculture and NaturalResources, offcring a generous start-up package. Re-quiires Ph.D. and postdoctoral experience. Send curricu-lum vitae, one-page statement of research interests, rep-resentative reprints/preprints, and three letters ofreference postmarked by 1 October 1990 (or until asuitabl candidate is found thereafter) to: Dr. Robert J.Spreitzer, Department ofBiochemistry, University ofNebraska-Lincoln, Lincoln, NE 68583-0718. Afir-matveActioEqual Opporunity Employer.

EUKARYOTIC MOLECULAR BIOLOGISTASSISTANT/ASSOCIATE PROFESSOR

The Department of Molecular and Cellular Biochem-istry of the Stritch School of Medicine at Loyola Uni-versity of Chicago is seeking to fill a faculty position atthe assistant/associate professor level in the area of eu-karyotic molecular biology. Preference will be given toapplicants interested in gene regulation, particularly thestudy of oncogenes. However, excellent applicants inother areas of eukaryotic molecular biology are invited.The successful applicant will be expected to initiate a

vigorous, innovative, and extramurally funded researchprogram, participate in medical school and graduateschool teaching, and interact coliaboratively with otherscientists within the university. Generous start-up fundsare available.Send curriculum vitae, research interests and goals,

recent reprints, and the names of three references to:

Richard M. Schultz, Ph.D., ChairmanDepartment of Molecular and Cellular Biochemistry

Loyola University of ChicagoStritch School of Medicine2160 South First AvenueMaywood, IL 60153

Loyola University of Chicago is an Equal Opportnity!AfirmativeAction Employer.

3I AUGUST 1990

ASSISTANT PROFESSORUNIVERSITY OF PENNSYLVANIA

SCHOOL OF MEDICINEDEPARTMENT OF ANATOMY AND

PENNSYLVANIA MUSCLE INSTITUTEA tenure-track assistant professor position is being

jointly offered by the Pennsylvania Muscle Institute andthe Department of Anatomy of the University of Penn-sylvania School of Medicine. The successful candidatewill be expected to establish an extramurally fundedresearch program using a molecular biological approachto study either gene regulation in muscle (preferredemphasis on development) or contractile protein struc-ture/function relationships. The position will also involvethe teaching of medical students (e.g., cell and tissuebiology) and participation in the training of graduatestudents and postdoctoral fellows.

Application deadline is 31 October 1990. Send curric-ulum vitae and three letters of recommendation to:Scarch Committee, c/o Dr. Yale Goldman, Director,Pennsylvania Muscle Institute, University ofPennsyl-vania School of Medicine, 37th and Hamilton Walk,Philadelphia, PA 19104-6085.

7he University of Pennsylvania is an Equal OpportunityEmployer.URBAN/PUBLIC HEALTH ENTOMOLOGISTThe Department of Entomology, University of Mary-

land, invites applications for a tenure-track appointmentas an ASSISTANT PROFESSOR Applicant mustdevelop and implement innovative management pro-grams for pests of structures and public health, conductresearch in support of these programs, and teach anannual course in urban pest management. Training in theprinciples and applicanon of IPM is essential and expe-rience with pests of structures and public health isdesirable. Send curriculum vitae, transcripts, statement ofinterests, and names and addresses of five references to:Dr. Michael J. Raupp, Department of Entomology,University ofMaryland, College Park, MD 20742 by30 September 1990. Telephone: 301454-7025. EqualOpportunity/Ajnnatve Acin Employer.

The Department of Molecular Biology at PrincetonUniversity invites applications for a tenure-track positionat the ASSISTANYPROFESSOR level in the area ofdevelopmental neurobiology. We are especially inter-ested in individuals who are working on the developmentor functioning ofthe nervous system in organisms whichare amenable to both genetic and molecular analysis.Applicants should send curriculum vitae, a summary ofresearch interests, and the names of at least three refereesto:

Developmental Genetics and NeurobiologySearch Committee

Department of Molecular BiologyPrinceton UniversityPrinceton, NJ 08544

Application deadline is 20 October 1990.Princeton University is an Equal Opportunity/Affimative

Action Employer.

BIOCHEMISTRY POSMIIONSThe Department of Biochemistry at Kansas State

University, a land-grant university, seeks applicants fortwo tenure-track positions, each with an appointment inthe Agricultural Experiment Station and the College ofArts and Sciences. Candidates for the ASSISTANT tothe JUNIOR ASSOCIATE PROFESSOR levels willbe considered with interests in diverse areas of contem-porary animal and plant biochemistry suitable to themission of the Agricultural Experiment Station. Weespecially encourage individuals with research back-grounds in membrane biochemistry, protein engineer-ing, protein processing, or signal transduction mecha-nisms to apply. All candidates should have postdoctoralexperience and substantial published work; be preparedto establish an independent, externally funded researchprogram; and be capable of teaching biochemistry toundergraduate and graduate students. Candidates seek-ing the rank of associate professor must have activelyfunded research programs. Applicants should send ar6sumi induding a statement of research plans and thenames of three references by 20 October 1990 to:Thomas E. Roche, Head, Departmcnt of Biochemis-try, Wiliard Hall, Kansas State University, Manhat-tan, KS 66506-3702. An Equal Oppornunity/AflimativeAction Employer.

PERSONNEL PLACEMENT 1057

POSITIONS OPEN POSITIONS OPEN

CELL BIOLOGISTMerck Sharp & Dohme ResearchLaboratories is offering an excellentcareer opportunity in the De-partment of Virus and Cell Biologyfor an endothelial cell biologist at theresearch facilities in West Point, PA,located 25 miles northwest ofPhiladelphia, PA.

The successful candidate for thisposition will play a leading role in amulti-disciplinary project involvingthe regulation of coagulation by theendothelium.

The position requires a Ph.D. orM.D. degree and three (3) yearsexperience in manipulation ofprimary cultures of endothelial cells.

Excellent salary and benefitprograms accompany this position.Please send curriculum vitaewith cover letter to: PersonnelManager, Ad #B-28, ResearchPersonnel, WP42-2, MerckSharp & Dohme ResearchLaboratories, West Point, PA19486.

EEO/AA/VH/Employer

ANATOMY POSMONASSISTANT/ASSOCIATE PROFESSOR ofAnat-

omy. Twelve-month, tenure-track position. Experiencein teaching medical gross anatomy and an earned doc-torate in anatomy with postdoctoral experience requiredThe individual is expected to develop and sustain afundable independent research program. Ultrastructuraland research facilities are available. Applicants shouldsend statement of interest, curriculum vitae, and threeletters ofrecommendation to: Dr. William J. Anderson,Chairman, Search and Screen Committee, TerreHaute Center for Medical Education, Indiana Uni-versity School of Medicine, 135 Holmstedt Hail,Terre Haute, IN 47809. Indiana University is an EqualOpportunity/Affirmative Action Employer.

BOTANIST: ASSISTANT/ASSOCIATE PRO-FESSOR. Ph.D. required, postdoctoral experience pre-ferred. The Biology Department, California State Uni-versity, Los Angeles, will fill a tenure-track facultyposition beginning fall 1991 for a person with researchinterests in an area of environmental biology involvingvascular plants; such as (but not limited to) autecology orvegetation studies, environmental restoration, or pollu-tion biology. The person will teach introductory botanycourses for majors and for nonmajors, and will have theopportunity to develop a course in their specialty field.An active research program involving undergraduate andgraduate students is expected. Submit curriculum vitae,statement of research p[ans, college transcripts, and threeletters of reference by 15 November 1990, to: Dr.Richard Vogl, Biology Search Committee, CaliforniaState University, Los Angeles, Los Angeles, CA90032-8201. Equal Opportunity/AffirmativeAction/Hand-icapped Employer.

Horn Point Environmental Laboratory (HPEL) andthe Agriculture Experiment Station of the University ofMaryland System are seeking applications for a jointtenure-track ASSISTANT/ASSCIATE PROFES-SOR position in the research area of nutrition/biochem-istry of aquatic invertebrates and fishes. Specialties ofinterest incude feeding and assimilation, with emphasison the nutritional role of natural and artificially preparedaquaculture diets. A Ph.D. in biochemistry or nutrition isrequired and postdoctoral experience is preferred. Thesuccessful candidate is expected to develop a strong andindependent research program as well as participate ingraduate education. Applicants should forward a state-ment of research interests, curriculum vitae, and namesand addresses of three references by 1 November 1990to: Dr. R. Harrell, HPEIL, Box 775, Cambridge, MD21613. Telephone: 301-228-8200. FAX: 301476-5490. The University ofMaryland is anAfomative Action/Equal Opportunity Employer.

SENIOR FACULTY POSMONIN RETROVIROLOGY AND DIRECTOR,CENTER FOR RETROVIRUS RESEARCH

THE OHIO STATE UNIVERSITYThe Department of Veterinary Pathobiology invites

applications for a tenure-track position as a semor facultyperson and director of the newly created Center forRetrovirus Research. The applicant should have a Ph.D.degree or equivalent with extensive research experiencein retrovirology or related fields, proven ability to obtainextramural research funds, and a strong commitment tograduate education. Maintenance of an independent,established research program with extramural supportand development of collaborative research efforts withfaculty and graduate students on animal and/or humanhealth-related retroviral disease problems are essential.Applications must include curriculum vitae, statement ofcareer goals, summary of current research activities, andnames of at least four individuals from whom letters ofreference may be solicited. Academic rank and salary arenegotiable. Deadline for applications is 1 December1990. Address correspondence to: Dr. Steven Kra-kowka, Chairman of Search Committee, Departmentof Veterinary Pathobiology, 1925 Coff{ey Road, Co-lumbus, OH 43210. The Ohio State University is an EqualOpportunity/Afirmative Ation Employer.

More than 150,000 people paid to see your ad inSCIENCE. Classified Advertising Department tele-phone: 202-326-6555. FAX: 202-682-0816.

ASSISTANT PROFESSOR. Tenure track, Depart-ment of Microbiology/Immunology. Successful candi-date will devote 75% of time to development of anindependent fimdable research program in any subdisci-pline ofmicrobiology, parasitology, or immunology, andalso participate tea g program of the department.Ph.D. required. Submit letter of application, curriculumvitae with research interests, and names of at least threereferences to: Gerald J. Tritz, Ph.D., Chairman, De-partment of Microbiology/Immunology, KirksvilleColiege of Osteopathic Medicine, 800 West JeffersonStreet, Kirksville, MO 63501. Equal Opportunity/Affir-mativeAtion Employer.

DEVELOPMENTAL NEUROSCIENTISTThe Department of Physiology and Cell Biology in-

vitcs applications for a tenure-track faculty position at therank of ASSISTANT, ASSOCIATE, OR FULLPROFESSOR to start 16 August 1991. Applicant musthave a Ph.D. in neuroscience or a related fed, postdoc-toral experience, and research experience in deveopmen-tal and molecular aspects of neuroscience. The successfulcandidate will be expected to maintain a strong indepen-dent research program and participate in the teaching ofundergraduate and graduate students. The salary will becommensurate with qualifications. Applications will bereviewed starting 1 December 1990 and thereafter untilthe position is filled. Applicants should send curriculumvitae, an outline of current and future research plan, andthe names of three references to: Dr. Jang-Yen Wu,Professor and Chair, Department of Physiology andCell Biology, 3038 Haworth Hall, University ofKansas, Lawrence, KS 66045. An Equal Opportunity!Aflmative Action Employer.

The Department of Molecular Biology at PrincetonUniversity invites nominations and applications for anENDOWED PROFESSORSHIP. Candidates shouldhead an active research program and have an establishedreputation for excellence in scholarly research. Preferencewill be given to candidates with a strong background andresearch interest in biochemistry. For further informa-tion, contact:

Professor Thomas ShenkLewis Thomas Laboratory

Department of Molecular BiologyPrinceton UniversityPrinceton, NJ 08544

Princeton University is an Equal Opportunity/AfimativeAction Employer.

CHAIRPERSON, DEPARTMENT OF CHEM-ISTRY, Indiana University-Purdue University at Indi-anapolis (IUPUI). Nominations and applications areinvited for this position in an expanding and developingdepartment. Candidates must have a research, funding

and teaching record to merit appointment at the rank of

professor, possess strong communication and interper-sonal skills, and, preferably, have prior administrativeexperience. Preference will be given to the areas oforganic chemistry, biochemistry, and analytical chemis-try, although all areas will be considered. Appointmentwill commence July 1991. Applicants should send cur-riculum vitae and names, addresses, and telephone num-bers of four references by 1 November 1990 to: Dr.Martin J. O'Donnell, Department of Chemistry-IU-PUI, 1125 East 38th Street, Indianapolis, IN 46205.IUPUI is an Equal Opportunity/AffirnativeAction Employer.

CRYSTALLOGRAPHIC LABORATORYDIRECTOR

An immediate full-time position is available. Respon-sibilities include: (i) supervision of Rigaku 200 x-raygenerator, Siemens area detector, and low-temperaturedevice; (ii) system management of VAX station 3200running under VMS; and (iii) software support forcrystallographic program packages such as XENGEN,CCP4, and X-PLOR. Opportumties to expand intographics workstation and UNIX network management.Familiarity and experience with x-ray generators andcrystallographic software is required and experience in

macromolecular crystallography is desirable. Women andminorities are encouraged to apply. Please send curriculumvitae and names of three references to: Dr. Craig Kun-drot, Department of Chenistry and Biochemistry,University of Colorado, Boulder, CO 80309. BIT-NET: KUNDROT@CECHEM.COLORADO.EDU.

SCIENCE, VOL. 249

POSITIONS OPEN

DevelopmentalBiologist

Applications are invited for aSenior or Junior tenure-trackfaculty position.Applicants should have at leastfour years of postdoctoral expe-rience and maintain a researchprogram in early developmentor tumorigenesis, using gene-tic, recombinant DNA, bio-chemical, immunolbgical, andcell biological tools to exploremechanisms of cell differenta-tion, growth control, cell tocell communication and deter-mination in a vertebrate sys-tem. The position includessupervision of graduate andmedical students and teachingin a related area.Send curriculum vitae, researchsummary and three letters ofreference to: Chainnan, Depart-ment of Cell Biology andAnatomy, CORNELL UNIVER-SITY MEDICAL COLLEGE,1300 York Avenue, New York,New York 10021. An EqualOpportunity/AffirmativeActionEmployer.

POSITIONS OPEN

POSITIONS OPEN

DIRECTOR, DIVISION OF EXPERIMENTALPATHOLOGY. The Department of Pathology andLaboratory Medicine of the University of Rochesterannounces a search for an experimental pathologist to beappointed director of the Division of Cell and MolecularPathology and George Hoyt Whipple Professor of Pa-thology and Laboratory Medicine. The research focus ofthis newly organized division is the elucidation of thecellular and molecular basis of human diseases. Theappointee will provide leadership to enhance and expandthe scientific endeavors of the department through re-cruitment of additional faculty and graduate and post-graduate trainees. Applications from individuals withM.D., M.D./Ph.D., or Ph.D. degree are welcome.

Interested candidates should submit by 30 October1990 their curriculum vitae and other credentials to:Search Committee for Division of Cell and MolecularPathology, c/o Dean A. Arvan, M.D., Department ofPathology and Laboratory Medicine, University ofRochester Medical Center, 601 Elmwood Avenue,Box 608, Rochester, NY 14642. Telephone: 716-275-5891. The University ofRochester is an Equal Oppor-tunity Employer, M/F.

PROGRAM DIRECTORMARINE-ESTUARINE-ENVIRONMENTAL

SCIENCES (MEES)UNIVERSITY OF MARYLAND SYSTEM

The University of Maryland seeks a director for itssystem-wide Graduate Program in Marine-Estuarine-Environmental Sciences. Students in this program maypursue M.S. and Ph.D. degrees at several campuses oftheUniversity of Maryland System, including at the Centerfor Environmental and Estuarine Studies (CEES) andthe Maryland Biotechnology Institute. More than 200students are enrolled at present.The successful candidate should have a strong research

program and teaching experience in some area of envi-ronmental science. She or he will have tenure within anappropriate department of the College of Agricultureand Life Sciences at the University of Maryland, CollegePark, and also carry the title of Associate Director forEducational Affairs in CEES. The MEES program direc-tor will be responsible for curriculum development,student admission, and coordination of participatingfaculty on a system-wide basis. She or he will develop acomprehensive program budget and seek both intra- andextramural support.

Applicants should submit a letter of interest, completecurnculum vitae, and the names of three references by 1November 1990 to: Chair, MEES Director SearchCommittee, Room 3220 Symons Hall, University ofMaryland, College Park, MD 20742-5571.The University of Maryland is an Equal Opportunity!

Afirmative Action Employer.

WWF World Wide FundFor Nature

RESEARCH ADVISER, CHINAWWF is the world's largest private international con-

servation organization with 27 affiliate and associatenational organizations on five continents. WWF aims toconserve the natural environment and ecological pro-cesses essential to life on earth.WWF is seeking to recruit a research adviser to

develop a comprehensive research program for WolongNature Reserve, Sichuan Province, China. The programwill cover both field research on the biology of the giantpanda and its habitat, and laboratory research and captivebreeding. It will be implemented by Chinese scientistswith the assistance and guidance of the research adviser.The position will be based on Wolong Nature Reserve

which is administered by the Ministry of Forestry of ThePeople's Republic of China. The activities of the adviserwill be part of an ongoing cooperative program betweenthe ministry and WWF.The position will require a Ph.D. in the biological

sciences and extensive experience in developing andsupervising research programs. Experience in China is anadvantage.

Applications, including a recent curriculum vitae andphotograph, should be submitted by 14 September 1990to: Mr. Chris Elliott, WWF International, Avenue duMont Blanc, CH-1196 Gland, Switzerland.

3I AUGUST 1990

F] lIJoin Wyeth-Ayer.st Laboratories, one of the world's Iargest pharmaceutical research ainddevelopment groups. Nozw is your o,)I)ortunity to become ain integral member of ourjfiist-paced, innovative team at our modern research Jacilily in Princeton, NewJfersey.Preference will be given to those afpplicants wilth a strong public(lion recordl in majorscienlific journals, history oJ scientific achievement and a demonstraled ability lo con-duct innovative research.

RES ,H SC]Ph.D.

ISIS

Pulmonary Pharmacologist/PhysiologistInvestigate the involvement of pulmonary inflammation in late phase asth-matic responses and airway hyperreactivity and establish appropriate invivo models for the evaluation of the pharmacologic activity of drugcandidates. A PhD in Pharmacology, Physiology, or a related medical sci-ence with 0-3 years post-doctoral training is required. Experience in themeasurement of pulmonary function in both small and large animal mod-els will be considered an asset.

Cellular ElectrophysiologistJoin an active research program in the study of ion channels and theirmodulation by drugs. Ideal candidate will be a PhD in Physiology,Pharmacology or Biophysics with 3-5 years relevant post-doctoral experi-ence. Must have expertise in the use of patch clamp techniques applied tothe study of K+ channel activity at both whole cell and single channel lev-els. Familiarity with the use of oocyte and mammalian cell expression sys-tems is also desirable.

Cellular ElectrophysiologistPostdoctoral Fellow

Study the regulation and pharmacological modulation of potassium channelsin airway smooth muscle using whole-cell and single channel voltage clamptechniques and work with collaborating academic investigators expert in thefield of airway smooth muscle electrophysiology. Ideal candidate will have arecent Ph.D. in Physiology, Pharmacology or Biophysics, and working knowl-edge of smooth muscle physiology. Familiarity with measurements of inter-nal calcium levels using fluorescent indicator dyes is useful.

Drug MetabolismDevelop analytical methods for the analysis of drugs in biological fluidsusing techniques such as HPLC, GLC, etc. The methods will be applied inpreclinical and clinical bioavailability and pharmacokinetic studies. Idealcandidate will have 3-6 years experience in the bioanalytical area andexperience in the area of quantitative analysis of drugs in biological fluids.Expertise in pharmacokinetics and statistics is an asset.

Biochemistry - Postdoctoral FellowStudy the role of nucleotide phosphodiesterases as regulators of cellularreactivity, and as potential pharmacologic targets. Will be responsible forestablishing novel methodologies to purify and characterize individualphosphodiesterase isozymes from various cell sources, and to investigatetheir physiological roles. A Ph.D. in Biochemistry or a related field isrequired, with experience in enzyme purification and kinetic enzyme analy-sis. Experience in cellular mechanisms of enzyme regulation and proteinpurification via HPLC are desirable.

We offer an excellent salary and benefits package plus opportunities forcareer advancement. Interested candidates should submit their curricu-lum vitae and salary requirements, stating position of interest, to: WYETH-AYERST RESEARCH, Personnel Manager, CN 8000, Princeton, NJ 08643-8000. An equal opportunity employer, M/F/H/V.

'"WYETHAYERST

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BiologIcalCemistry

Continued expansion of biomolecularly targeted drugdiscovery efforts at PARKE-DAVIS, a Warner-Lambert Company, has provided openings for Ph.D.-level scientists in our new Department of BiologicalChemistry. Help us to establish the department andits research directions.

Positions in enzymology, bio-organic and proteinchemistry will be central to the establishment of amajor venture in biological chemistry at PARKE-DAVIS. You will design and implement new enzymekinetic assays for novel compounds, and determinestructure-function relationships, for example, via stud-ies utilizing site-directed mutagenesis. Or you will par-ticipate in the isolation, purification, and characteriza-tion of natural and recombinant proteins. Receptors,catalytic or non-catalytic antibodies, and anti-idiotypicantibodies as well as enzymes, may ultimately fallwHthin the scope of your work.

Qualified candidates will, for example, have at leasttwo years' research experience in performing quan-titative studies of enzyme-catalyzed reactions, com-puter-assisted kinetic analyses and equilibrium-bind-ing studies of protein-ligand interactions. Familiaritywith standard biochemical techniques and modemmethods of protein chromatography and electrophor-esis is essential. An understanding of the principlesof molecular biology and biophysics is also expected.

Close, interdisciplinary working relationships will beestablished with PARKE-DAVIS, scientists in com-puter-assisted drug design, structural biology andchemistry, and molecular genetics. You will also workwith our outstanding in-house group of medicinalchemists, biochemists, and pharmacologists, amongothers, as well as with well-known outside collabora-tors in many disciplines. With the University of Mich-igan "next door", candidates will become part of a dis-tinguished research environment.

Good oral and written communication skills are im-portant. And because of the need to work with as wellas to be a part of multidisciplinary groups, this positionrequires an ability to interact effectively with a varietyof scientists operating at the leading edge of drug dis-covery.

This is an exciting time for the pharmaceutical indus-try. The convergence of state-of-the-art technologiesallows us to begin to answer questions previously un-answerable. Join us and contribute to acceleratingprogress in drug discovery and the medical sciences.

Interested individuals should send their CV to JackMoyer, PARKE-DAVIS, Pharmaceutical ResearchDivision, Warner-Lambert Company, 2800Plymouth Road, Ann Arbor, Ml 48105. "Smoke-Free Work Environment"

"Equal Opportunity In Action"

PARKE-DAVIS

PHARMIACOLOGISTTOXICOLOGIST

Neurobiology &Molecular Biology

Regeneron Pharmaceuticals, a company

dedicated to developing therapeuticagents for degenerative and traumaticneurological diseases, is seeking to applyrecent advances in the understanding ofneuronal growth and regeneration.

Regeneron is seeking a pharmacologist/toxicologist to oversee preclinical safetyand efficiency testing of our novelrecombinant neurotrophic molecules.Industry experience and background inneuropharmacology are essentialrequirements for this position.

Regeneron's modern facility is locatedon a 275-acre wooded campus inWestchester County, 20 miles north ofManhattan, near major universities andmedical centers. We offer an excellentcompensation package, including gener-ous stock options. Suburban Westchesterfeatures attractive and affordable housing,outstanding public schools and recrea-tional facilities along with ready accessto the cultural and business centers ofNew York City.

Please forward your resume, inconfidence to: Ms. Carol Deaken,Regeneron Pharmaceuticals, Inc.,777 Old Saw Mill River Road,Tarrytown, NY 10591-6706.Equal opportunity employer.

REGENEiRONPharmaceuticals, Inc.A DIVISION OF WA RAERL=.j

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THE UNIVERSITYAL~L OF ADELAIDE

SOUTH AUSTRALIAApplications are invited from both women and men for the following positions:

LECTURER/SENIOR LECTURER IN ANIMAL SCIENCES(Tenurable) (Two positions)in the DEPARTMENT OF ANIMAL SCIENCES at the WAITE AGRICULTURAL RESEARCHINSTITUTE.Ref. 7453 is in the area of ANIMAL BIOCHEMISTRY. Appliconts should have a solidbockground in biochemistry and knowledge of nutritional and metabolic biochemistry,preferably with research interests in protein biochemistry and the control of growth anddevelopment throuqh genetic and protein engineering, he a pointee will be required toteach an undergraduate course in nutritiona biochemistry of farm animals, to superviseundergraudate and post-graduate research students, to initiate a research programmeon the cellular and moleculor biology of animal growth and development and to interactwith research groups in animal productions, wool biology, reproduction and animalbiotechnology.Ref. 7454 is in the area of MOLECULAR BIOLOGY for the study of reproduction inanimals. Applicants should have experience in molecular and cellular biology of animalspreferably with research interest in the area of animal transgenesis and gene expressionduring development. The appointee will be required to teach in undergroduote andpost-graduote courses in Animal Cell and Molecular Biotechnology, and ReproductiveBiology & Technology, to supervise undergraduate and post-graduate research students,to initate a research programme in the area of animal transaenesis and the cellular andmolecular biology of animal reproduction and to interact with research groups in malereproduction and reproductive immunology.The successful appliconts would be expected to hold a Ph.D. degree or have equivalentprofessionol troining and experience in an appropriate discipline.The positions are available immediately.Further information concerning the duties of the position may be obtained from, ProfessorBP Setchell, Head of the Deportment ofAnimal Sciences, telephone (61 8) 372 2297.LECTURER/SENIOR LECTURERIN CEREAL MOLECULAR BIOLOGY(Tenurable) (Two positions)(Refs. 7451 & 7452) at the WAITE AGRICULTURAL RESEARCH INSTITUTE. Theappointees will be required to undertake original research, supervise postgraduatestudents and teach undergraduate courses in the Deportments of AgriculturalBiochemistry and Agronomy. The Departments would be porticularly intestested toreceive applicationsfrom molecular biologists with expertise in the following areas:

i) methods of mapping molecularprobes particularly in the temperate cerealsi!) gene identification, isolation and cloning andiii) the control of gene expression.However, molecular biologists with demonstrated skills in other areas of relevance tocereal molecular biology and itsapplication to cereal improvement will be considered.The successful applicants would be expected to hold a Ph.D. degree or have equivalentprofessionol training and experience in an appropriate discipline.The positions are available immediately.Further information concerning the duties of the positions may be obtained from,Professor DRMarshall, Head of the Deportment ofAgronomy, telephone (61 8) 372 2279.

LECTURER IN SOIL PHYSICS(Tenurable) (Ref: 7455)SENIOR LECTURER IN SOIL BIOLOGY/MICROBIOLOGY(Tenurable) (Ref: 7456)in the DEPARTMENT OF SOIL SCIENCE at the WAITE AGRICULTURAL RESEARCHINSTITUTE.(Ref. 7455) The appointee will participate in teaching in the Faculty of Agricultural andNatural Resource Sciences and the Faculty of Science and be the focus for thedevelopmentof research in the physicsof soil waterand its interactionwith structure.Soil Science is taught in the ordinary and Honours degree in the B.Ag.Sc. and soil physicsspecifically in the subjects Soil Water and Soil Conservation and Management. TheDeportment of Soil Science cooperotes closely with the CSIRO Division of Soils and theSouth Australian Department of Agriculture in teaching and research.Applicants must posses the degree of Ph.D. in soil physics, hydrology or a closely relatedarea.(Ref. 7456) The appointee will participate in teachin9 in the Faculty of Agricultural andNatural Resource Sciences and the Faculty of Science and be the focus for thedevelopment of research in soil biology, microbiologyand biochemistry.Soil Science is taught in the ordinary and Honours degree in the B.Ag.Sc. and electives inthe B.Sc. including Soil Biology and Biochemistry. The Department of Soil Sciencecooperates closely with the CSIRO Division of Soils and the South Australian Departmentof Agriculture in teaching and research.Applicants must posses the degree of Ph.D. in biology or microbiology.The positions are available immediately.Major interest in the department include aspects of soil structure, tillage, carbon andnitrogen cycling, plant nutrient supply and the movement of water and colloids in soilsand iandscapes. The Waite campus, which includes the CSIRO Divisions of Soils andWater Resources, and the South Australian Department of Agriculture, has available awide range of sophisticated research equipment and experimental field sites.Further information concerning the duties of the positions may be obtoined fromProfessor JM Oades, Head of the Department of Soil Science, telephone (61 8) 372 221 0.

It is University policy to encourage women to apply for consideration for appointment totenurable academic appointments. Holders of full-time tenured or tenurable academicappointments have the opportunity to take leove without pay on a half-time basis for aspecific period of up to ten years when this is necessaryforthe care of children.INFORMATION about the general conditions of oppointment and selection criteria maybe obtained from the Director, Personnel Services at the University.SALARY per annum: Lecturer: AUS$33,163 x 7 -AUS$43,096Senior Lecturer: AUS$43,984 x 5 -AUS$51,015APPLICATIONS, IN DUPLICATE, quoting relevont reference number and giving fullpersonal particulars (including whether candidates hold Australian permanent residencystatus), detoils of academic quolifications and names and addresses of three refereesshould reach the Director, Personnel Services at the University of Adelaide, GPO Box 498,Adeloide, South Australia, 5001, Telex UNIVAD AA 89141, Facsimile (61 8) 224 0464not later than 30 September 1990.The University reserves the right to make enquiries of any person regording anycandidate's suitability for appointment, not to make an appointment or to appoint byinvitation.

From January 199 1 Roseworthy Agricultural College vwill merge with the University of Adelaide.

THE UNIVERSITY OF ADELAIDE IS AN EQUAL OPPORTUNITY EMPLOYER. '(

A k,l

POSITIONS OPEN

CHAIRPERSON. Department of Neurology,School of Medicine, University of California, San Fran-cisco (UCSF). Qualified candidates are invited to applyfor the position as chairperson of the Department ofNeurology at the UCSF School of Medicine. Applicantsshould submnit curriculum vitae, bibliography, and thenames offour references to: Dorothy F. Bainton, M.D.,Chair, Search Committee for Chair ofNeurology, c/oJoyce McKinney, Office of the Dean, School of Med-icine, University of California, San Francisco, SanFrancisco, CA 94143-0410. UCSF is an AffirmativeAction/Equal Opportunity Employer. Women and minoritiesare particularly urged to apply.

MANAGER, PRODUCT DEVELOPMENT. Su-pervise chemist in design of pharmaceutical soft gelatincapsule dosage for various medicinal drug products.Evaluate both chemical and pharmacological aspects ofthe drug products. Requires academic background inpharmacy, Ph.D. in medicinal chemistry, and 1 year ofexperience in job offered or 1 year of academic researchexperience in pharmacology. Salary: $50,000 per year;40 hours per week. Job site/interview: Chatsworth,California. Send this ad and resume to: Job#MD17569, P.O. Box 9560, Sacramento, CA95823-0560 no later than 16 September 1990.

ENVIRONMENTAL RESOURCES MAN-AGER. Seeking ecologist to supervise EnvironmentalDivision. Work involves environmental research, moni-toring, management, planning, permitting, and publiceducation primarily in aquatic and wetland habitats. M.S.in environmental biology and 3 years of experience;prefer Ph.D. Strong written, oral, computer, supervisory,scuba, and public contact skills are necessary. Salary:$27,747.20 to $42,536.00. Send resume to: City ofCape Coral, P.O. Box 150027, Cape Coral, FL33915-0027, Attention: Personnel Departnent.

BIOCHEMISTRY FACULTY POSITIONSUNIVERSITY OF WISCONSIN-MADISONThe University of Wisconsin-Madison Biochemistry

Department invites applications for two tenure-trackpositions at the ASSISTANT OR ASSOCIATE PRO-FESSOR level. We are particularly interested in appli-cations from individuals whose research emphasizes met-abolic regulation (assistant or associate professor level) ormolecular neurobiology (assistant professor level); how-ever, outstanding candidates in an area of biochemistrywill be considered. The successfl candidates are ex-pected to develop vigorous independent research pro-grams and participate in the undergraduate and graduateteaching of general and specialized biochemistry courses.Applications, including curriculum vitae, list of publica-tions, summary ofpast work and accomplishments, and astatement of plans for future research, should be sent to:Professor William S. Reznikoff, Chairman, Depart-ment ofBiochemistry, University ofWisconsin-Mad-ison, 420 Henry Mall, Madison, WI 53706. In addi-tion, applicants should arrange for at least three letters ofreference to be mailed to the same address. Applicantsshould state in their cover letter for which position theywish to be considered. To assure consideration, allapplication materials should be received by 1 October1990. The University of Wisconsin-Madison is anAffirmativeAction/Equal Opportunity Employer and encourages applica-tionsfrom women and minorities.

FACULTY POSITIONSIN PHARMACOLOGY

The Department of Pharmacology at the University ofAlabama at Birmingham (UAB) invites applications fortwo tenure-track positions at the ASSISTANT PRO-FESSOR and ASSOCIATE PROFESSOR level avail-able in the fall of 1990. Individuals will complementpresent faculty research and teaching interests in chemo-therapy, particularly in the areas of cancer, AIDS andAIDS-related opportunistic infection. The successful ap-plicant(s) will be expected to have potential to attractextramural support and be able to establish an indepen-dent research program. Associate professor candidatesmust demonstrate a strong research record with currentfunding. Responsibilities will also include teaching ofmedical/dental and graduate students. Send letter ofapplication with curriculum vitae and three names ofreferences to: Dr. Robert B. Diasio, M.D., Professorand Chairman, University of Alabama at Birming-ham, Department of Pharmacology, Box 402 VolkerHall, UAB Station, Birmingham, AL 35294. UAB isan Affirmative Action/Equal Opportunity Employer.

POSITIONS OPEN

DIVE OPERATIONS SUPERVISOR. Head sci-entific dive department, including 5.5-million-gallon salt-water tank maintenance, all underwater activities, diveequipment, logs, safety, assistance with marine animalcare; participate in active research. Requires extensivescientific diving experience, dive instructor certification,graduate degree or pursuance of one in ocean sciencefield, knowledge of marine science, biology, oceanogra-phy, and specialized underwater equipment. Superb lead-ership skias and strong interest in interacting with alllevels. Apply to: Paul Buss, Professional Staffing, WaltDisney World Co., P.O. Box 10,000, Lake BuenaVista, FL 32830 by 30 September 1990.

MOLECULAR BIOLOGY OFMICROBIAL PATHOGENESISJUNIOR OR SENIOR FACULTY

POSMIIONS AVAILABLEThe Department of Microbiology and Immunology in

the College of Medicine at The University of Tennessee,Memphis, invites applications for several junior or seniorlevel, tenure-track positions focusing on significant prob-lems in microbial pathogenesis using genetic and molec-ular aSproaches. Senior candidates should have a strongrecod of research accomplishment with sustained pro-gram growth and development. Junior candidates will beexpected to develop a high quality, independent researchprogram with long-term growth potential. Teachingresponsibilities, which emphasize quality rather thanquantity, include medical, dental, and graduate students.The University of Tennessee, Memphis, is well into amajor growth phase. The department has recently movedinto a completely renovated building and will be appoint-ing at least five new faculty during the next several years.New faculty are also being appointed in the Departmentsof Anatomy, Pharmacology, and Biochemistry.A large Center of Excellence grant has resulted in

establishment of a Molecular Resource Center within thedepartment featuring state-of-the-art facilities for: oligo-nucleotide synthesis, peptide synthesis, monoclonal anti-body production, amino acid analysis, protein sequenc-ing, polymerase chain reaction, molecular graphics, andflow cytometry. Funds for the initiation of fesearchprograms will be available and salaries will be highlycompetitive.

Applications will be received until 1 October 1990 oruntil the position is filled thereafter. Applications shouldconsist of curriculum vitae, copies of several recentpublications, a brief statement of future research goals,and three letters of reference to be sent to:

Dr. Terrance G. CooperDepartment of Microbiology and Immunology

The University of Tennessee, Memphis858 Madison Avenue, Room 801

Memphis, TN 38163The University ofTennessee is an AffirmativeAction/Equal

Opportunity Employer, Section 504, Title IX.

POSITIONS OPEN

WEST VIRGINIA UNIVERSITYFACULTY POSMIION IN

PHARMACOLOGY/TOXICOLOGYWest Virginia University invites applications for a

tenure-track position at the ASSISTANT PROFES-SOR level. Applicants should have a doctoral degree inpharmacology, toxicology, or related discipline and post-doctoral research experience. Research accomplishmentsand evidence of ability to develop independent, exter-nally funded research will be prime considerations in theselection process. Applicants should submit curriculumvitae, including complete bibliography, and request threeletters of reference be sent to: Dr. Robert E. Stitzel,Department of Pharmacology and Toxicology, WestVirginia University Health Sciences Center, Morgan-towvn, WV 26506 by 1 October 1990. Preference will begiven to applicants whose research focuses on cellularmechanisms, especially those related to ion transportprocesses. Teaching responsibilities require a broadknowledge of pharmacology.

West Virginia University is an Affirmative Action/EqualOpportunity Employer. Minority and women applicants areparticularly welcome.

FACULTY POSITIONThe Department of Biological Chemistry at The Uni-

versity of Texas Health Science Center at Houston,Dental Branch, has an opening for a tenure-track facultymember at the ASSISTANT PROFESSOR level. Can-didates should hold a Ph.D. in biochemistry or in anappropriate related field and have at least 2 years ofpostdoctoral experience. The successful candidate will beexpected to conduct independent research, to attractoutside research support, and to participate in teachingof biochemistry to dental students. Preference will begiven to individuals with research expertise and interestin mineralized tissues, calcium transport, odontoblastand osteoblast differentiation, and other areas related tooral tissues.Send a cover letter, curriculum vitae, and names and

addresses of three references to: William T. Butler,Ph.D., Chairman, Department of Biological Chemis-try, University of Texas Dental Branch, P.O. Box20068, Houston, TX 77225.The University of Texas Health Science Center at Houston

is an Equal Opportunity/AffirmativeAction Employer. Womenand minorities are encouraged to apply.

DEVELOPMENTAL BIOLOGISTSt. Mary's College ofMaryland is seeking a permanent,

full-time developmental biologist to begin either in Jan-uary or August 1991. Instructional responsibilities in-clude courses in developmental biology, introductorybiology, and specialty area. Strong commitment to un-dergraduate teaching and involving undergraduate stu-dents in research are both expected. Ph.D. required.Rank and salary based on level of experience. St. Mary'sCollege of Maryland is a state-supported, liberal artscollege with 1500 students. The college's waterfrontcampus is located in historic St. Mary's City, 70 milessoutheast of Washington, D.C. Closing date for receiptof applications is 15 October 1990. Send curriculumvitae, three letters of reference, and statements of teach-ing/research interests to: Dr. Robert Paul, DivisionHead, Division of Natural Science and Mathematics,St. Mary's College of Maryland, St. Mary's City, MD20686. Women and minorities are urged to apply. EqualOpportunity/Affirmative Action Employer.

UNIVERSITY OF QUEENSLANDLECTURER TENURABLE/LECTURER

DEPARTMENT OF ANATOMYThe successful appointee will be required to contribute

to the teaching of topographical and functional anatomyto students enrolled in subjects within the health andbiological sciences. Applicants should have demonstrateda research capability in an area of functional anatomy orhuman biology and will be expected to supervise post-graduate students in these areas. Reference No.: 40090.

Further information is available from the Head ofDepartment, telephone: 07-377-2722.

Salary: lecturer, $33,163 to $43,096 per annum;5-year fixed term.

Closing date: 28 September 1990.Please forward an original plus seven copies of appli-

cation and resume to: Director, Personnel Services,The University of Queensland, QlD 4072, Australia.

Equal Opportunity in Employment is University Policy.

SCIENCE, VOL. 249

.F>W '''r-l,MstiCr'

ANNOUNCINGA NEW SERVICE FROM

SCiENCENow you can pay for your line classified

ad with a credit card - we acceptMasterCard and VISA.

Please let us know on your ad orderthat you wish to take advantage of thisservice, or ask us for further details.

SCIENCE Classified AdvertisingTel: 202-326-6555 FAX: 202-682-0816

r

LI062

nCD A warRCLI LIr A nEMORY UNIVERSITY SCHOOL OF MEDICINE UvrAf 1 mrn- 1 fcAU

Department of Microbiology and Immunology ECOLOGY, ETHOLOGY, AND EVOLUTION

CHAIR UNIVERSITY OF ILLINOIS

Emory University School of Medicine invites nomina- The University of Illinois at Urbana-Champaign invites nominations and

tions and applications for the position of Chair for the applications for the positon of Head of the Department and Professor ofEcology, Ethology, and Evolution. The department has 12 faculty and 12

Department of Microbiology and Immunology. Respon- affiliated faculty. The administration has made a strong committment to further

sibilities include the direction, management, and con- development of population biology and several new openings exist fortinuing development of a department committed to ex- recruitment of faculty members. Collaborative research opportunities are

possible with the State Natural History Survey, Institute for Environmentalcellence in research and teaching In a university setting. Studies, Museum of Natural History, other departments in the School of Ufe

The faculty has teaching responsibilities for the M. D. Sciences, and departments in the Colleges of Agriculture and Veterinary

degree program of the Medical School and also for the Medicine. Campus facilities and resources available to the department inciludePh.D.e deogree pograms oedical through Gra dthe several nearby natural areas, including forest, restored prairie, and old-fieldPh.D. degree programs offered through the Graduate habitats, collections in the Museum of Natural History, Herbarium, and State

School of Arts and Sciences. The department is located Natural History Survey, greenhouses, a National Center for Supercomputingin ultramodern facilities in the Rollins Research Center Applications, a Biotechnology Center offering services for recombinant DNAon the Emory Campus and is adjacent to the Centers for technology and protein sequencing, and a Center for Genome Analysis.Disease Control. The department has a very active We seek a person who holds a Ph.D. degree, has a distinguished, active

research effort and candidates must hold an M.D. or Ph.D. research program in an area of population biology, such as theoreticalpopulation bioiogy, population genefics, or behavioral ecology and has

degree with training in microbiology or immunology, and demonstrated leadership qualities. Submit nominations or applications with

have a strong record in research. Previous academic and curriculum vitae and names and phone numbers of three references to:

administrative responsibilities are required, as well as Dr. Carol K. Augspurgw, Chair

demonstrated leadership capabilities. Salary is nego- EEE Department Head Search CommIttee

tiable. Applications should include a current curriculum Universty of Illinois

vitae and the names ofappropriate references, and should 393 Morrill Hallbe submitted no later than October 1, 1990 to: Urna, IL 61801

Microbiology and Immunology Search Committee Telephone: 217-333-1298; FAX 217-244-1224

312 Woodruff Health Science Center In order to ensure full consideraton, applications must be received by 1

Emory University School of Medicine October 1990. Salary is negotiable. Preferred starting date is 21 August 1991.

The U=niversity of Illinois is an Affirmative Action/Equal Opportunity Employer

Emory University is an Equal Opportunity/Affirmative Action Employer.

MALARIA PROJECT ASSOCIATE FACULTY POSITION, MARINE SCIENCEThe Institute of Marine Science, School of Fisheries and

American Association for the Advancement of Sci- Ocean Sciences, is seeking an outstanding scientist for atenure track position in teaching and research in the area of

ences (AAAS) Sub-Saharan Africa Program seeks oceanography with interest in remote sensing techniques. The

International Public Health Specialist for year- position will be filled at the Assistant Professor level or above

long study of malaria prevention and control strate- depending on background and experience. The successfulapplicant will be expected to develop a vigorous research

gies in Africa, carried out by multidisciplinary program in oceanography oriented toward remote sensing of

working group of African and US scientists and high latitute waters, as well as participate in teaching and

practitioners. guidance of graduate students. Examples of potential areas ofresearch include primary production, environmental changes

Requirements for position include graduate degreeassociated with global warming, or marine mammal migrations.The University of Alaska Fairbanks is developing a major

related to international health, preferably tropical remote sensing capability through the Alaska SAR facility thatdiseases. Broad background in public health and will offer new opportunities in this area of research. The Institute

issues desirable. Excellent research,of Marine Science has a faculty of 26 with a graduate enroll-

development issues desirable. Excellent researcn, ment of 40-50 students. The faculty are involved in a variety of

writing, and managerial abilities necessary. Prefer- research programs emphasizing arctic and high latitude seas.

ence given to candidate with field experience in Applicants should send a summary of research interests with

Sub-Saharan Africa. Candidate must be willing to a curriculum vitae and the names, addresses, and phonetravel abroad. numbers of three references to:

Donald M. SchellTwelve-month position, available immediately. Chair, Remote Sensing Search CommitteePlease send letter of interest and curriculum vitae c/o Director's Office

to: Institute of Marine ScienceUniversity of Alaska Fairbanks

Mr. Gregory Stokes Fairbanks, AK 99775-1080Human Resources Closing date for applications is 15 October 1990. Applications

MAS of finalists may be subject to public disclosure. Persons hired

1333 H Street, N.W., Suite #850must comply with the new employment provisions of theFederal Immigration Reporting Act. The University of Alaska is

Washington, D.C. 20005 an Equal Opportunity/Affirmative Action Employer.

I

SENIOR MASS SPECTROSCOPISTAnalytical Sciences Department

Fisons Pharmaceuticals is a rapidly expanding multi-national ethical pharmaceutical com-pany. The Analytical Sciences Department determines the chemical structure of all compoundssynthesized in our medicinal chemistry research programs, the purity of metabolites andchemical impurities. Due to expansion of the Rochester facility, a vacancy now exists inAnalytical Sciences for an experienced Mass Spectroscopist. Immediate duties will include thedesign of a new spectroscopy laboratory and the acquisition and implementation of additionalspectrometers, including tandem quadrupole and magnetic sector instruments. The successfulapplicant will provide scientific leadership and be responsible for the work and growth of theMass Spectroscopy Unit, and will be expected to maintain a state-of-the-art laboratory. Workingin close collaboration with colleagues throughout the drug discovery and development process,the incumbent will design and interpret experiments to elucidate chemical structures. In additionto scheduling and operating our own excellent instrumentation, this incumbent will be expectedto liaise with colleagues in Fisons analytical laboratories in the UK and to organize contractwork. Excellent communication skills and a broad knowledge of synthetic and analytical chemistryare essential. Some supervisory experience would be helpful, as would a working knowledge ofrelated technologies such as NMR, chromatography, and the latest MS interfaces and sampleintroduction systems.

The ideal candidate should possess a doctorate in chemistry, analytical science, spectroscopyor a closely related discipline, with additional graduate training in determining the structure ofunknown species from a variety of chemical classes. Previous successful experience in aresearch-based pharmaceutical company is preferred, and analytical familiarity with smallpeptide molecules would be an advantage.

Fisons is located in Rochester, NY, an area noted for its excellent family environment, affordablehousing, cultural attractions, and year-round recreational activities. We provide excellent salaryand benefits in addition to opportunities for personal growth and professional advancement.Please send resume including salary history to: Employment Office, FISONSPHARMACEUTICALS, P.O. Box 1710, Rochester, NY 14603. Reference Ad #RRP 760.

IFisons Pharmaceuticals Corporation

No Agency Referrals PleaseWe Are An Equal Opportunity Employer M/F/HN

POSITIONS OPEN

BIOCHEMISTRY FACULTY POSMONUNIVERSITY OF WISCONSIN-MADISONApplications are invited for an ASSISTANT PRO-

FESSOR position in the Department of Biochemistryand the Department of Nutritional Sciences of theUniversity olf Wisconsin-Madison. Exceptional candi-dates at the ASSOCIATE PROFESSOR level will beconsidered. The successful candidate will be expected todevelop a strong research program utilizing modembiochemistry to study problems of nutritional interest.This indudes organismal and cellular nutrition. Dutiesindude teadiing the departments' graduate and under-graduate courses and the training of graduate and post-doctorate students. Applications including curriculumvitae, publication list, one-page summary of past accom-plishments, and a one-page plan offuture research shouldbe sent to: H. F. DLuca, Chairman, Search Commit-tec, Department of Biochemistry, University ofWis-consin-Madison, 420 Henry Mall, Madison, WI53706. Applicants must also arrange for three letters ofrecommendation to be sent to the same address. Toassure consideration, complete applications should bereceived by 1 October 1990. The university is an Affir-matie A chon/Equa Opportunity Employer and encourageswomen and minoriies to apply.

SUMMER FACULTY POSMONS IN THESPACE LIFE SCIENCES

TRAINDNG PROGRAM (SLSTP)A NASA PROJECT

Four PROJECT COUNSELOR positions are openin the 1991 SLSIP to be held at the Kennedy SpaceCenter, Florida. Project counselors will be involved inthe implementation of the 7-week-long program (start-ing mid-June 1991) activities for undergraduate scienceand engineering college students. An applicant must havea minimum ofM.S. degree, preferably Ph.D. degree, andsome ecperience of teaching and research in life sciencesand related fields. If interested, please send a letter ofapplication, complete curriculum vitae, and three lettersof recommendation before 31 December 1990 to:

Program DirectorSLSTP

Florida A&M UniversityCollege of Pharmacy

and Phar tical Sciences106 Honor House

Tallahasee, FL 32307Telephone: 904-599-3623/3636

The Division of Pharmacology and ExperimentalTherapeutics at the University of Kentucky College ofPharmacy invites applications for a tenure-track FAC-ULTY POSMIION in the area of gene expression andmolecular biology. Qualifications indude a Ph.D. inbiochemistry, pharmacology, or dosely related disciplinewith relevant postdoctoral experience. While preferencemay be given to individuals complementing the division'scurrent strengths in drug metabolism, neurosciences, andcardiovascular-pulmonary pharmacology, outstandingcandidates with credentials in other contemporary areasare encouraged to apply. The successful applicant will beexpected to establish an extramurally funded researchprogram and to assume modest responsibilities for teach-i at the undergraduate and/or graduate level. Rank,

and tenure status will be commensurate withexperience. Candidates should submit curriculum vitae, astatement of research interests, and the names of threereferences no later than 15 October 1990 to: Dr. RobertA. Blouin, Chair, Pharmacology Search Committee,University of Kentucky, College of Pharmacy, Lex-ington, KY 40536-0082. F.ualOpporinit /innAnion Employer.

SCIENCE, VOL. 249

Sr. ResearchSientist

R.W. Johnson Pharmaceutical Research Institute (PRI) is a first-class,worldwide drug research organization and a member of the Johnson &Johnson Family of Companies with the strength and backing to meet thechallenges of today's competitive environment.We currently have a key position for a highly-motivated professional

with a PhD or equivalent in Microbiology or Molecular Biology and 2-5years of experience in a microbiology laboratory. You'll perform researchon mechanism of action of drugs and for new potential therapeutics; de-velop new approaches to discovery of potential clinical candidates; andconduct studies to evaluate possible licensing opportunities. Will also in-teract with Medicinal Chemistry to conduct structure activity relationships.We offer a competitive salary and the comprehensive benefits you

would expect from a Johnson & Johnson Company including our on-siteLIVE FOR LIFE Wellness Program. Please forward your resume, includingsalary history, to: Mr. Thomas Hutton, Dept. 28A, R.W. Johnson Pharma-ceutical Research Institute, P.O. Box 300, Raritan, New Jersey 08869-0602.An Equal Opportunity Employer, M/F

§KKR.W JOHNSON

PHARMACEUTICAL RESEARCH INSTITUTEA 9 m n Compony

BONUS CIRCULATIONFOR YOUR CIASSIFD AD

Our issue of 5 October 1990 will be distrib-uted to scientists attending two important meet-ings: IBEX (San Mateo, California, 23 to 25October) and Expoquimia (Barcelona, Spain, 5to 8 November). Deadline or submission of linecassified ads: 20 September 1990.

SCENCE Classified AdvertisingTelephone: 202-326-6555

FAX: 202-682-0816

POSITIONS OPEN

PHYSIOLOGYFACULTY POSMION

FALL 1990

The Department of Physiology and Neurobiology atthe University of Connecticut is recniiting a lecturer toteach human anatomy and physiology (a two-semestercourse with lectures and laboratories) at the Torringtoncampus. The candidate will also play a major role in thedevelopment of our undergraduate curriculum in thehealth sciences department at the main campus in Storrs.This in a nontenure-track, full-time position subject toyearly renewal. Active research is not a part of thisposition. The salary will be commensurate with experi-ence (up to the ASSISTANT PROFESSOR level); a

Ph.D. is desired. Candidates should send curriculumvitae and the names of three references to: Professor G.Pilar, Head, Department ofPhysiology and Neurobi-ology, U42, 75North Eagleville Road, University ofConnecticut, Storrs, CT 06269. Contact the depart-ment for a complete job description at 2034864326.The University ofConnecticut is an Afirmative Action/EqualOpportunity Employer. (Search #1A32.)

=tl- m m mm-mm- -im_______ _-_ -qnc.Ecogen, Inc., an agricultural biotechnology company

locate in the Philadelphia area, has immediate openingsfor several positions in its microbial pesticide develop-ment group.

Individuals with B.S. or M.S. level training and expe-rience in the following research areas are sought:* Immunology/immunochemistry* Molecular biology* Microbial genetics/physiology* Cell biology* Fermentaton technology* Analytical protein chemistryInterested candidates should submit a current resume

including the names, addresses, and telephone numbersof three references to:

Personnel DirectorEcogen Inc.

2005 Cabot oulevard, WestLanghorne, PA 19047-1810

Ecogen is an Equal Opportunity Employer.

As a part of a major expansion over the next year,Diagnon Corporation is seeking to fill several positaons,to include the following:

* Ph.D.: Pharmacologist/endocrinologist with knowl-edge and experience in radioimmunoassay and biochem-i enzyme assays.

* Ph.D.: Reproductive physiologist with strong bio-chemistry background.

* D.V.M.: Laboratory animal experience.* M.S.: Biochemistry or biology with knowledge of

biochemistry and some laboratory experience.* B.S.: Several positions open. Experience in the

following: immundlogy, endocrinology, radioimmuno-assay, and diagnostic techniques.

Eligible applicants should submit curriculum vitae to:Mariha O'Neill, Human Resources Manager, Diag-non Corporation, 15215 Shady Grove Road, Suite306, Rockville, MD 20850.

PLANT PATHOLOGISTS

Crop Genetics International seeks plant pathologists tojoin its expanding bioherbicide research team. The suc-

cessful candidates will join a research team developing a

novel weed control methodology based on the use ofunique, plant-associated prokaryotes and chemical stress-ing agents. Research opportunities exist in the discovery,characterization, and evaulation of microorganisms; de-velopment of bioassay systems; and assessment of plant-microbe-herbicide interactions. Creative scientists with atleast an M.S. in plant pathology and with demonstratedability to direct their creativity to solving real worldproblems are encouraged to apply. Candidates shouldsubmit their resume and the names of three references inconfidence to:

Crop Genetics InternationalX-tend Discovery Team7170 Standard DriveHanover, MD 21076

31 AUGUST 1990

The UpjohnCompany, arecognized leader in worldwide pharmaceutical and agriculturalproducts research, is seeking ahighly-qualified, highly-motivated veterinarian to assumethe responsibilities of Director, Animal Support and Lab Services, in its Upjohn Labora-tories Division, located in Kalamazoo, Michigan.Principle responsibilities include the provision of veterinary medical and husbandryservices, and establishment of policies and practices that ensure compliance withregulatory standards for the use and care of laboratory animals. The successful candidatewill be responsible for directing a multi-disciplinary support group comprised of 70+veterinary, technical service and animal care staff members.Requirements include aDVM/VMD degree, ACLAM certification, and a minimum of 7years experience managing an animal care program that has consistently maintainedAAALAC accreditation. The candidate must have demonstrated interpersonal andcommunication skills. Successful experience directing a preventive medicine programkeeping a large, diversified laboratory animal population in good health and free ofdisease is essential.Thecompensationpackage will becommensurate with qualifications and experience, andincludes relocation assistance. Upjohn offers a stimulating, multidisciplinary researchenvironment at our modern laboratories in Kalamazoo. In 1989, Upjohn committed over$400 million to research and development efforts and is presently increasing its mainresearch facility by 509%o. Qualified and interested candidates are encouraged to send acurriculum vitae and summary ofacademic andmanagement experience in confidence to:THEUPJOHNCOMPANY,CORPORATE RECRU1TING/6002-HA, KALAMAZOO,MI 49001-9988. Please refer to position number 6002-HA in your cover letter. An EqualOpportunity Employer M/F.

Our Commitment to Scintifc Excellence Continues...__~~~~~~~

..:...::-:'''..'::0

.........zzZ|

Director/Associate- Director0''t0'i''-WSl000 00-0 ''-i00Bristol-Myers Squibb is -a develo

pharmaceutical products. The 0Bristol-Myers Squibb Pharmaceutical Research lnstituU

currently has challenging opportunities to makesgnificant contributons to the inter-

disciplinary product developm..nprocess ... rug de MYou will work closely with all the gou.ps involved in both Prelno.Xclinical development studies, as welil. .h'.1teulatory Afars and B.usiness. ssss<':' ''"Development Departments, to plan.,,. )rrslement. and monitonr deveop.ment acviies' """''from identification of a drug candi'deisteto DAapprovelai,.',,. marke t0l'aunch. Speific':1responsibilities include working with mul5tidsiplinary protect teams-a'nd, various devel-''opment departments to prepare Interdisciplinary DeveilopmeFnt Plans tand schedulef" or

each new drug candidate, comprehensive''Q:uarterly tatsflprts for all wsorldwidedevelopment projects, and keeping projecs on track,"'' ""''"''""Ideal candidates will have a PhD in the medical sci'enc'es(PharmMicrobiology, Immunology), and 7 to 10 yeafrs expserisencei-n tpharmaceutical industry

R&D, along with direct experience in anti-infectives, CNS or cancer R&D. Experience

in project management and multiple drug development areas is desired, along with

excellent interpersonal, organizational and communication skills.

We offer a stimulating scientific environment in our modern research facility in

Wallingford, Connecticut. As part of a newly formed and growing department, you

will have significant opportunity for growth and receive an excellent salary/benefits

package. For confidential consideration, please forward your curriculum vitae to:

Bristel-Myers Squibb Pharmaceutical Research Institute, Dept. SL, P.O. Box 5101,

Wallingford, CT 06492-7681. An equal opportunity employer, M/F/HNV.

Bristol-Myers Squibb

Pharmaceutical Research Institute

.

* Bristol-Myers Squibb Company

ES,

M.

ONCOGEN-ONCOGEN, a division of Bristol-Myers Squibband a leader in biotechnology, performs researchdedicated to pursuing novel approaches to the de-velopment of therapeutic products in the areas ofimmunology, infectious diseases and cancer.ONCOGEN is currently recruiting for the follow-ing positions:

Scientist, Assay DevelopmentResponsibilities include development of biologicaland biochemical assays for growth factor, anti-body and vaccine-related project utiliation (includ-ing appropriate bench work); quantitative analysisof generated data and development of validationreports and documents; and supervision of techni-cal staff. Requires PhD or MS, 4 to 5 years assaydevelopment experience, good understanding ofEIAs (ELISAs) and functional biologic assays,and good writing and organizational skills. Under-standing of computer systems helpful. Please ref-erence position #90-052.

Scientist, Cell Banking/GMP ProductionResponsibilities include pilot scale production ofGMP and research antibody grade lots and growthmodulators; drafting and implementation of docu-ments related to GMP cell banking and produc-tion; and biological and biophysical analyses forrn-process testing to monitor production levels andproduct quality including ELISA, SDS-PAGE,Westem blots and simple enzyme assays. Re-quires PhD or MS in biochemistry, cell biology orrelated field with experience in tissue culture andphysical techniques in biochemistry. Documenta-tion experience and familiarity with DOS, WORD,EXCEL or similar softwarc desirable. Please refer-ence position #90-045.

Manager, Scale-Up ProcessesFocus will be on mammnalian cell culture processdevelopment. Responsibilities include cell lineoptimization, cell banking, small scale GMP pro-duction, research material production and funda-mental bioprocess R&D such as bioreactor processdevelopment; and recruitment and supervision ofsenior scientific staff. Requires PhD in cell biol-ogy or related field, 4 to 5 years' industrial experi-ence, demonstrated supervisory skills, experiencein scale-up of mammalian cells in a variety ofbioreactors, and experience with producing thera-peutic proteins under cGMPs. Please referenceposition #90-047.ONCOGEN offers a creative work environment,competitive salaries and an excellent benefit pack-age. Qualified applicants, please submit resumeto: J. McGough, ONCOGEN, 3005 First Av-enue, Seattle, WA 98121. An Equal OpportunityEmployer.

VAV A Bristol-Myers Squibb Company

ISIS

PHARMACEUTICALSCAREER OPPORTUNITIES INANTISENSE THERAPEUTICSREGULATORY AFFAIRS/DRUG

DEVELOPMENT SENIOR SCIENTISTISIS Pharmaceuticals, located in Carlsbad, CA, focuses onantisense oligonucleotide therapeutics. The company is seekingcandidates for the position of Senior Scientist, RegulatoryAffairs/Drug Development to work in areas relating to thepreclinical and clinical development of antisense drugs derivedfrom our Research and Drug Discovery Programs.The successful candidate will coordinate, implement and docu-ment a variety of activities required for IND and NDA submis-sions. These will include: participation in the design of preclini-cal and clinical development strategies and plans, identificationand selection of extramural investigators and laboratories toperform various development functions, budget negotiation,monitoring of ongoing studies, maintaining documentation andevaluating results, assisting in the development and monitoringof intramural GLP/GMP procedures, and preparation of regula-tory documents.Candidates must have a Ph.D. in the chemical or biologicalsciences, pharmaceutical industry experience and at least threeyears of drug development and regulatory experience. Out-standing oral and written communication skills are essential, asis the ability to work well as part of a multi-disciplinary team.ISIS Pharmaceuticals offers a competitive salary, excellentbenefits and equity participation. Please reply with curriculumvitae and names of references to: Christopher K. Mirabelli,Ph.D., Vice President, Research, ISIS Pharmaceuticals, 2280Faraday Avenue, Carlsbad, CA 92008. An Equal OpportunityEmployer.

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Lorillard, a leading3 manufacturer of tobacco prod-ucts, has an immediate opening for a Toxicologistat our Greensboro, N.C Research Center.The successful candidate's responsibilities will includeparticipation in internal research and testing activi-ties, primarily in the area of genetic toxicology, aswell as protocol development, study monitoring,and report evaluation in an extramural toxicologytesting program.

Requirements include a Ph.D. degree, 0-10 yearsexperience, and excellent communication skills. Anability to accurately read, evaluate, and interpretscientific literature is required, as are the writing skillsnecessary to communicate key elements to others.A background in genetic and in vitro toxicity assess-ment is desirable.Lorillard offers a comprehensive flexible benefitspackage, relocation assistance, and a competitivesalary. Qualified candidates should forward theirc.v. and salary requirements to:

Halle S. Jessup

Research CenterBox 21688 GreensborQ NC 27420

An Equal Opportunity Employer M/F,/H

ProteinCrystallographyat Monsanto

Protein crystallography positions are available at Monsanto forpostdoctoral associates. You will work closely and collaboratewith biophysicists, biochemists and molecular biologists onproblems related to health care, animal nutrition and plantscience. The positions also offer possibilities for training ingenetic engineering techniques. Available projects include struc-ture determinations of a tight complex between a protein hor-mone and a soluble fragment of its receptor HIV proteasecomplexes with synthetic inhibitors; substrate/inhibitor com-plexes of the glyphosate taret, enolpyruvyl shikimate 3-phos-phate synthase. The crystal ography laboratories are equippedwith two Rigaku 12 KW rotating anode generators, two dualchamber Xuong-Hamlin area detector systems and an AFC5single crystal dtfflrctometer. Computng and moleculargraphicsfacilities include a CRAY X-MP EA/11 6se supercomputer, a VAX1 11/780, an FPS-264 arrayprocessor, three Evans and SutheriandPS300 graphics terminals and a Silicon Graphics 4D25TG workstation. Our salaries are competitive. Candidates with back-grounds in macromolecular crystallography are encouraged toapply; experience with low temperature crystallography or withdata acquisition at synchrotron sources would be a plus. Candi-dates with exceptionally strong backgrounds in small moleculecrystallography will also receive serious attention.For consideration, please send resume and references to:J.B. Bussen; Manager, Human Resources; MONSANTOCOMPANY; Mall Zone BB5B;700 Chetbrfleld Village Parkway;St. Louis, MO 63198. For more Information contact WilliamStallings (314)537-7236. Monsanto is an Equal OpportunityEmployerM/F/HN.Careers tor people with ideas

Monsanto Ii

The Biomedical R&D Division of GEO-CENTERS, INC has immediate openings fortechnical staff positions in support of our R&Dactivities at various facilities throughout theU.S. Applicants for all positions must possessU.S. Citizenship, and will be evaluated on theireducational background and practical experience,as demonstrated by a solid publication recordin the appropriate field.

Research Immunologist - Code 2164:Great Lakes, IL A Postdoctoral level candi-date is sought to conduct research on thedevelopment of immunoassays which are rele-vant to the diagnosis of oral infectious diseases.The successful candidate will possess extensiveexperience in cell-mediated immunology, andwill have demonstrated practical expertise withassociated laboratory techniques and proce-dures. Prior experience with assay developmentfor oral pathogens is a definite plus.

Mlicrobiologist/Immunologist - Code 2186:Bethesda, MD A Postdoctoral level candidateis sought to conduct investigations involvingthe isolation and characterization of stem cellsfrom HIMSIV seropositive subjects. The idealcandidate will possess a recent PhD in Microbi-ology or Immunology, and will have 2-3 yearsof demonstrated practical experience in cultur-ing cells infected with infectous agents. Previ-ous experience with HIV infected samples andP-2 level facilities is considered a plus. Candi-dates 'will also be evaluated on communications(oral and written) skills.

Immunology Technicians (3 Positions) -

Code 2187: Bethesda, MD Support staffmembers are sought to assist our seniorresearch staff in research activities relating tocell culture and analysis of HI'VS1V infectedcell lines. Qualified candidates will possess a BSdegree in Microbiology or Immunology, and2-3 years' practical experience (or an MSdegree) with HIV infected cell lines.

Biochemistry Technician - Code 2188:Bethesda, MD A support staff member isbeing sought to assist senior staff in the prepa-ration of gels, blots, etc. Qualified candidateswill have a BS degree in Biochemistry or arelated field, and will require a minimum of 2years of demonstrated practical laboratoryskills.GEO-CENTERS, INC, offers competitivesalaries, and an excellent relocation andbenefits package. Qualified applicants shouldsend their resumes, salary history, and references,in confidence, to: GEO-CENTERS, INC.,10903 Indian Head Highway, Fort Washing-ton, MD 20744, Attn: Deborah Hall-Greene/Code__ (Please indicate the appropri-ate code). An Equal Opportunity/AffirmativeAction Employer.

GEO-CENTERS, INC.

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POSITIONS OPEN

IMMUNOLOGIST. Responsible for scientific lead-ership and supervision of a laboratory involved in thestudy of inflammatory and immunologic potential ofcorneal epithelial cells, keratocytes, and lymphoreticularcells in a rat model of vitamin A deficiency. Emphasis ison the detection and identification of cytokines, particu-larly interleukins which can regulate chemotaxis and therelease of proteolytic factors responsible for tissue deg-radation. Minimum requirements include an M.D. orPh.D. in biological sciences and 6 months of postdoc-toral experience in immunology, including comeal in-flammation and immunity and cytokine research. Alsorequired is expertise in designing and interpreting bio-logical assays, immunocytochemistry, ELISA, RIA,immunoblottinp, flow cytometry, and initiation andmaintenance of primary cultures and cell lines. Salaryrange is $25,000 to $30,000 per year for a 5-day,37-hour week. Qualified applicants should respond withresume in duplicate to: J.O. #00841, MassachusettsDepartnent of Employment and Training, SpecialPrograms Department, 19 Staniford Street, Boston,MA 02114.

POSTDOCTORAL POSITION. Position in radiol-ogy contrast agent development available immediately.U.S. citizen or permanent resident. Projects include devel-opment and testing of novel contrast agents for CITscanning of the liver and spleen. Background in pharma-cology or toxicology preferred. Contact: Dr. Steven E.Seltzer, Department of Radiology, Harvard MedicalSchool, Brigham and Women's Hospital, 72 FrancisStreet, Boston, MA 02115. Telephone: 617-732-6301. An Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL POSITIONS. Available tostudy the regulation of the intracellular phospholipasesthat mediate stimulus-response coupling in mammaliancells. Projects include delineation of the mechanismsresponsible for the activation of intracellular phospholi-pases A2 as well as studies directed toward their cloning,expression, site-directed mutagenesis, and intracellularprocessing. Candidates should be recent Ph.D.'s withexperience in protein chemistry, lipid chemistry, or mo-lecular biology. Send curriculum vitae and the names oftwo references to: Richard M. Gross, M.D., Ph.D.,660 South Euclid, Box 8020, Washington University,St. Louis, MO 63110.

POSTDOCTORAL POSIION, MOLECULARENDOCRINOLOGY. Dana-Farber Cancer Institute,Harvard Medical School. The Dana-Farber Cancer Insti-tute is seeking to fill a research position at the postdoc-toral level for studies on the regulation of hepatic P-450genes by pituitary-dependent hormones. Prior researchexperience in molecular and/or cell biology is highlydesirable. Joint appointment will be held in the Depart-ment of Biological Chemistry and Molecular Pharmacol-ogy at Harvard Medical School. Flexible start date. Sendcurriculum vitae, representative publications, and namesof three references to: Dr. David J. Waxman, JF-525,Dana-Farber Cancer Institute, Harvard MedicalSchool, 44 Binney Street, Boston, MA 02115. AnAffirmative Action/Equal Opportunity Employer.

NUMERICAL OCEAN CIRCULATION MOD-ELING. Institute of Marine and Coastal Sciences, Rut-gers University. Applicants are sought for one or morePOSTDOCTORAL POSMIIONS in numerical oceancirculation modeling. Current group activities include:(i) coupled physical/biological modeling ofthe CaliforniaCurrent System and other eastern boundary currentregimes; (ii) basin-scale modeling of the wind and ther-mally driven ocean circulation in the North Atlantic andNorth Pacific oceans; and (iii) development and applica-tion of advanced ocean circulation models having novelphysical (e.g., intermediate equation), numerical (spec-tral finite element), and/or computational (massivelyparallel) design. Candidates should have a Ph.D. inphysical oceanography, computational fluid dynamics, ora closely related field, as well as experience with super-computers and Unix workstations. Send letters of inter-est with current curriculum vitae, a statement of researchinterests, and the names of three references to:

Professor Dale B. HaidvogelInstitute of Marine and Coastal Sciences

Rutgers UniversityPost Office Box 231

New Brunswick, NJ 08903-0231Rutgers University is an Equal Opportunity/Affirmative

Action Employer.

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POSITIONS OPEN

UNIVERSITY OF MANITOBAFACULTY OF MEDICINE

POSTDOCTORAL POSITION

Available for training in neurochemistry/neurobiologyrelated to cholinergic systems and the role of membranephospholipids and their phospholipases in signal trans-mission. Some experience in enzymology and molecularbiology useful.Send curriculum vitae and names of references to:

Dr. J. N. KanferDepartment of Biochemistry and Molecular Biology

Faculty of MedicineUniversity of Manitoba770 Bannatyne Avenue

Wimnipeg, Manitoba, Canada R3E 0W3

POSTDOCTORAL POSITION. Available immne-diately to study intracellular organeliar calcium pumpsusing molecular, biochemical, and cellular approaches.Experience in molecular biology or membrane proteinbiochemistry is desirable; U.S. citizenship or permanentresidency status required. Send resume, a brief statement ofinterests, and the names of three references to: JonathanLytton, Ph.D., Renal Division, Brigham and Wom-en's Hospital and Harvard Medical School, 75 Fran-cis Street, Boston, MA 02115.

POSTDOCTORAL FELLOWSHIP IN AIDSRESEARCH AT THE UNIVERSITY OFCALIFORNIA, SAN DIEGO (UCSD)

The AIDS research group at the University of Califor-nia, San Diego, announces the availability of postdoc-toral training fellowship for both U.S. citizens andforeign nationals who plan to return to their nativecountry at the completion of training. Research interestsof the participating faculty members include molecularvirology, AIDS pathogenesis, molecular immunology,animal models, and drug development. The research willbe conducted in state-of-the-art facilities, including thenewly constructed Clinical Sciences Building on the LaJolla campus.

Participating faculty include D. Carson, R. Kornbluth,D. Looney, M. Lotz, D. Mosier, D. Richman, D.Spector, S. Spector, W. Wachsman, C. Wiley, and F.Wong-Staal.

U.S. citizens address inquiries to:

Douglas D. Richman, M.D.Department of Medicine, V-111-FUniversity of California, San Diego

La Jolla, CA 92093Foreign nationals address inquiries to:

Dennis A. Carson, M.D.Department of Medicine, S-045

University of California, San DiegoLa Jolla, CA 92093

UCSD is an Equal Opportunity Employer.

THEORETICAL NEUROBIOLOGYThe Neurosciences Institute (NSI) invites applications

for positions as INSTITUTE FELLOWS in Theoreti-cal Neurobiology. The NSI supports an inhouse researchprogram dedicated to developing experimentally testabletheoretical models of neural systems. Current modelsinclude simulations of pharmacological effects on neu-ronal networks, the design of network automata, andanalysis of visual systems. Advanced supercomputer fa-cilities are available.

Institute Fellows are appointed for 2 years with thepossibility of renewal, and receive stipends that dependon quacation and experience. Applicants should be atthe postdoctoral or assistant professor level, and musthave a background in experimental or theoretical neuro-science or related fields.The NSI is an independent organization located on the

campus ofThe Rockefeller University in New York City.The NSI serves as the home of the NeurosciencesResearch Program and is an international center of studyand research for distinguished visiting neuroscientists.Fellows have opportunities to use the Institute's exten-sive facilities and to interact with visiting scientists.

Applicants should send a short statement of researchinterests, curriculum vitae, and the names of three refer-ences to: Dr. W. Einar Gall, Research Director, TheNeurosciences Institute, 1230 York Avenue, NewYork, NY 10021.

POSITIONS OPEN

POSTDOCTORAL POSMIION. Available imme-diately to study the hormonal regulation of gene expres-sion in plants. Experience in basic molecular technimuessuch as mRNA isolation, Northern analysis, and o ersare required. Send curriculum vitae and names of threereferences to: Dr. R. N. Arteca, Pennsylvania StateUniversity, Department of Horticulture, UniversityPark, PA 16802. Telephone: 814-863-2252. An Af-firmative Action/Equal Opportunity Employer.

Three POSTDOCTORAL POSMIIONS to study(i) molecular biology ofskin cytochrome P-450 and skincancer, (ii) skin photosensitization and photodynamictherapy of skin cancer, and (iii) diet and cancer chemo-prevention. Ph.D. with relevant experience desirable.Send curriculum vitae with names of references to:Professor Hasan Mukhtar, Research Director, De-partment of Dermatology, Case Western ReserveUniversity, Cleveland, OH 44106.

POSTDOCTORAL. A 1-year appointment with op-portunities for renewal for a second and third year, for aninorganic chemist to do exciting and challenging work inTc-99m and Re-186 radiopharmaceutical research anddevelopment, while working with seven Ph.D. inorganicchemists under the direction of Dr. Edward Deutsch.This position will provide an ideal opportunity for thecandidate to gain experience and training in both radio-pharmaceutical development in an industrial setting andin the use of pharmacological structure-activity relation-ships. The successful candidate will have experience ininorganic and organic synthesis; experience with bio-chemistry and/or the use of radiation is desirable. Sendresume, three letters of recommendation, and transcriptsto: Dr. Dennis Nosco, Mallinckrodt Medical, Inc.,675 McDonnell Boulevard, St. Louis, MO 63042.Equal Opportunity Employer.

POSTDOCTORAL POSMIION, BIOCHEMIS-TRY AND MOLECULAR BIOLOGY OF PRO-TEINS. Funded position to study structure-functionrelationships in tropomyosin and troponin C using site-directed mutagenesis. Experience in protein biochemistryand/or recombinant DNA is desirable. Send curriculumvitae, research interests, and the names ofthree referencesto: Dr. Sarah Hitchcock-DeGregori, Department ofNeuroscience and Cell Biology, University of Medi-cine and Dentistry ofNew Jersey (UMDNJ), RobertWood Johnson Medical School, 675 Hoes Lane,Piscataway, NJ 08854-5635. The UMDNJ is an Affir-mative Action/Equal Employment Opportunity Employer, MIF/H/V, and a member ofthe University Health System ofNewJersey.

N EW E R S EY

POSTDOCTORAL POSMIIONMOLECULAR GENETICS

HARVARD SCHOOL OF PUBLIC HEALTHA position is immediately available to study the regu-

lation of genes induced by oxidative stress in E. coli.Research training includes identification of promoters,purification of regulatory proteins, and characterizationof the interactions between them. Knowledge of molec-ular biological techniques preferred; experience withprotein purification is a plus. Send curriculum vitae, astatement of research interests, and names of three eval-uators by 15 October 1990 to: Dr. Spencer Farr,Laboratory of Toxicology, Harvard School of PublicHealth, 665 Huntington Avenue, Boston, MA02115. An Equal Opportunity/AffirnmtiveAction Employer.

POSTDOCTORAL RESEARCH SCIENTISTPostdoctoral research scientist with suitable experience

in techniques used to study the electrophysiology andpharmacology of the in situ canine heart and also tech-niques used to evaluate antiarrhythmic drug action onisolated cardiac tissues and single cardiac myocytes forgrant-supported studies on mechanisms of action ofantiarrhythmic drugs. Familiarity with electrocardio-graphy and clinical cardiology desirable. Applicantsshould send research interests, curriculum vitae, andthree letters of recommendation to: Dr. Brian F. Hoff-man, Chairman, Department of Pharmacology, Co-lumbia University, 630 West 168th Street, NewYork, NY 10032. Columbia University is an Equal Oppor-tunity/Affrmative Action Employer.

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BRISTOL-MYERS SQUIBB CCENTRAL NERVOUS SYSTEBristol-Myers Squibb is a worldwide leader in the research anddevelopment of novel pharmaceutical products. Our success isderived from a commitment to scientific research, and ourfuture will be molded by individuals who strive for scientificexcellence and innovation.The Central Nervous System Drug Discovery group, located inWallingford, CT, will undergo a significant expansionthroughout 1990-1991, with positions available at Ph.D., andnon Ph.D levels. Specific additions to our staff will includeindividuals from the following disciplines:

Behavioral PharmacologistsSeveral positions are available for Ph.D., B.S./M.S. individualsskilled in assessing the psychotropic activity of compoundsthrough the use of behavioral models. Areas of importanceinclude anxiety, depression, schizophrenia, facilitation ofcognitive processes, and recovery of function followingCNS trauma.

Neurochemists and ElectrophysiologistsWe are specifically seeking a Ph.D skilled in the use ofmicrodialysis techniques applied to the serotonergic anddopaminergic systems. An opportunity for a PostdoctoralFellow with interests in serotonin receptor/G-protein

the development of novel CNS drugs.To apply, please send resume and salary history to: Bristol-Myers Squibb Pharmaceutical Research Institute, Dept. SS-SC/CNS, P.O. Box 5101, Wallingford, CT 06492-7661. An equalopportunity employer, M/F/HN.

Bristol-Myers SquibbPharmaceutical Research Institute

*BBristol-MYes Squibb Company

Post Doctoral FellowResearch Associate

NeuroImmunologyNOVA PHARMACEUTICAL CORPORATION,a leading Research & Development company inBaltimore, MD, seeks a Ph.D. scientist to participatein a study examining HIV-1's actions in the centralnervous system. Emphasis is on neurochemicalmechanisms involving AIDS-associated neuropathy.The ideal candidate will have a Ph.D. with a strongbackground in radio-receptor binding, ion channels,second messenger systems and tissue culture.A working knowledge of immunology is desirable.This position is NIH funded for 2 years.NOVA PHARMACEUTICAL CORPORATION offersa competitive salary and benefits package whichincludes company-paid health, life and dentalinsurance; profit sharing; 401(k) plan. For immediateconsideration, please send your resume alongwith a brief statement of research experience andinterests, and the names of three references to:NOVA PHARMACEUTICAL CORP., Personnel-90-070, 6200 Freeport Centre, Baltimore, MD21224. Nova is an equal opportunity employeroffering a smoke-free work environment.

II NOVA>%* PHARMACEUTICAL CORPORATION

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PATHOLOGY/TOXICOLOGYThe Department of Pathology and Toxicology, SmithKlineBeecham Pharmaceuticals, is seeking a Postdoctoral Fellow tostudy the comparative pathogenesis of biliary epithelial cellhyperplasia. The Fellow will have a unique opportunity tojoin a multidisciplinary team from Experimental Pathology,Toxicology and Drug Metabolism, thereby gaining broad ex-posure to preclinical development in the pharmaceutical in-dustry. The team will investigate potential mechanismscontributing to chemically-induced biliary epithelial cell injuryand repair. The successful candidate will investigate the struc-tural and functional alterations associated with biliary epithe-lial cell injury and relate these changes to hepatic metabolismand biliary excretion of xenobiotics.

A Ph.D. in Pathology, Toxicology, Biochemistryor a related field is required. Relevant experience in hepato-biliary physiology, or knowledge of in vivo or in vitro tech-niques to investigate hepatobiliary disease is desirable. Thesuccessful candidate will be expected to present the results ottheir work at national meetings and publish in peer-reviewedjournals.

Based in a new state-of-the-art research facilityin suburban Philadelphia near Valley Forge, SmithKlineBeecham provides a stimulating and challenging scientific en-vironment in which to grow and excel. We offer an attractivecompensation/benefits and relocation package. Please sendresume to H.R. McConnell E153 Employment Administrator,SmithKline Beecham Pharmaceuticals, P.O. Box 1539, King of

Prussia, PA 19406. We are anEqual Opportunity Employer,M/F/H/V.

SmithKline BeechamPharmaceuticals

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CONSERVATION COORDINATORAUSTRALASIAN SPECIES MANAGEMENT PROGRAMME

THE ORGANISATIONZoos & Aquariums in the Australasian region are committed to jointly managing theiranimal collections in support of conservation. Accordingly, the Australasian RegionalAssociation of Zoological Parks and Aquariums (ARAZPA) and the Council ofGoverning Bodies of Australasian Zoos (COGBAZ), have together established theSpecies Management Coordinating Council (SMCC). The SMCC is responsible to itscontributing institutions for the development of species management policies,procedures and plans and for assisting institutions in their implementation.THE POSITIONWe are seeking a qualified, experienced scientist/manager to lead the development ofconservation strategies for the Zoos and Aquariums of the Australasian Region. Thesuccessful applicant is expected to have or be willing and able to quickly acquiretechnical competencies of a high order in population genetics and conservationbiology and microcomputing. Preference will be given to applicants with a soundworking knowledge and experience of international wildlife conservation. The ability tonegotiate complex international agreements between organisations is required.Experience in or aptitude for grant writing and other fund-raising is highly desirable.The Conservation Coordinator is required to train and motivate others and to achieveresults at all levels from practical to policy.

The Conservation Coordinator is responsible to the SMCC, functions as its chiefexecutive and is accountable for the day to day administration of the AustralasianSpecies Management Programme, the development of regional conservation strategiesand coordination with similar national, regional and global programmes involving zoos,aquariums and field conservation organisations.THE LOCATIONThe Office of the Australasian Species Management Programme will be established inserviced premises in an Australian capital city (Sydney, Melbourne, Perth, Adelaide) tobe determined through negotiation with the successful applicant. The ConservationCoordinator will travel regularly interstate and occasionally overseas.

SALARY & CONDITIONSAppointment will be at a salary in the range of A$43,984 - A$51,015 p.a. (comparableto Australian Universities Senior Lecturer Range) depending upon qualifications andexperience. Contribution to a Superannuation Scheme is negotiable. 4 weeks annualleave, 10 days paid sick leave p.a., 13 weeks long service leave is due after 10 years.

ENQUIRIESFurther details of the position are available from John DeJose, Director, Perth Zoo,P.O. Box 489, South Perth, 6151, Western Australia or FAX 09-367-3921 or by phoning09-367-7988.

Applications addressing the selection criteria should be forward to Dr. RobertBaker, Chairman, Conservation Coordinator Selection Committee, Adelaide Zoo, FromeRoad, Adelaide, South Australia, 5000, Fax 08-239-0637 by 1 October 1990.

PROFESSOR OF BIOENGINEERINGAND PHYSIOLOGY

The Harvard School of Public Health, Department of Environ-mental Health is seeking a Professor of Bioengineering andPhysiology in the area of respiratory biology. A PhD or MD isrequired. The successful candidate should be well-establishedin applying the tools of engineering science to investigation ofrespiratory system funciton and dysfunction. He or she musthave demonstrated research, administrative, and teachingskills.

Active areas of research should include both experimentaland theoretical investigations of fundamental issues in fluid flowin the respiratory tract, material properties of the lungs andchest wall, and connective tissue mechanics. The successfulcandidate should also be able to contribute to various ongoingaspects of research into air pollution exposure assessment andcontrol.

The Harvard School of Public Health is committed to increas-ing representation of women and minority members among itsfaculty and particularly encourages applications from suchcandidates.

Send resume, names of three references, and three repre-

sentative publications to:

Dr. Joseph J. Harringtonad hoc Senior Search CommitteeDivision of Applied SciencesHarvard UniversityPierce Hall 113Cambridge, MA 02138

POSTDOCTORAL AND PREDOCTORALResearch Positions Available

inRegulation of Gene Expression

atVanderbilt UniversitySchool of Medicine

Fellowships are available immediately to support research studies in the area ofmolecular mechanisms of gene regulation. Positions are available in the labs/research areas listed below. Collaborative research projects between laboratoriesare particularly encouraged. Interested persons should contact Dr. Chalkleydirectly at the address given.

The available research laboratories and research topics are:

Wayne Anderson - Three dimensional structure of proteins involved in transcription.

Roger Chalkley Developmental control of chromatin structure in gene expression.

Daryl Granner - Hormonal regulation of gene transcription and mRNA stability.

Mark Magnuson - Tissue specific expression and regulation of the glucokinase gene.

Roland Stein - Regulation of insulin gene expression in mammalian cells.

Tony Well Molecular genetic analyses of yeast general transcription initiation factors.

Dr. Roger ChalkleyDepartment of Molecular Physiology and Biophysics

Vanderbilt UniversitySchool of Medicine

Nashville, Tennessee 37232

Tel.-615-322-7051Fax-615-322-7236

Vanderbilt University is an equal opportunity/affirmative action employer.

Call for Nominations

The Roger J. Williams Award inPreventive Nutrition

This award is presented for outstanding contributions to theprevention of disease and promotion of health through nutrition.The award, which includes a cash prize of $5,000, commemo-rates the pioneering nutritional research of Roger J. Williams,Ph.D., founding director of the Clayton Foundation BiochemicalInstitute of the University of Texas at Austin. Nominees will beconsidered in terms of the magnitude of their contributions toany aspect of preventive nutrition. The award is made possiblethrough the generosity of Mr. and Mrs. E. Bruce Street, Sr. ofGraham, Texas.

Nominations for the award should include: (1) the nominee'sname and address; (2) a description of the contributions of thenominee relevant to preventive nutrition; and (3) a statement ofthe social and scientific impact of these contributions. Thename, address, telephone number and signature of the individ-ual making the nomination should be included.

Please submit nominationsby November 1, 1990 to:

Screening CommitteeThe Roger J. Williams Award in Preventive Nutrition

Texas College of Osteopathic Medicine3500 Camp Bowie Blvd.

Fort Worth, Texas 76107-2690 USAFAX Number 817-735-2283

ScientistsCivilian Employment Opportunities

Department of National Defence

If you are a recent or upcoming graduate of an advanceduniversity program in the natural or social sciences or a relatedfield, consider this opportunity to apply your expertise as a

civilian scientist with DND. You will join a team of over 580talented professionals who enjoy rewarding careers in appliedresearch and development; social, economic and strategicanalysis; and operational research.

Positions are currently available or anticipated near

Halifax (Nova Scotia), Quebec City (Quebec), Ottawa (Ontario),Toronto (Ontario), Medicine Hat (Alberta) andVictoria (British Columbia) in the following fields:

Biology - microbiology, pharmacology, toxicology,physiology, biophysics and radiobiology

ChemistryComputer ScienceEconomicsEngineering (except forestry and geology)Military HistoryMathematics - applied mathematics and operational researchPhysicsExperimental PsychologyPolitical Science - strategic studies and international

relationsSociology

To qualify, you must possess or be completing a master's or

doctorate degree from a recognized university, with highacademic standing in one of the above fields. Due to thenature of the work, all employees require a security clearance.Preference will be given to Canadian citizens.

Starting salaries range from $30,000 to $45,000,commensurate with your position and qualifications. Benefitlevels and salary advancements are fully competitive.

To apply, forward your resume and/or application form to theaddress listed below, indicating your primary field of interest.Please enclose copies of all your academic transcripts and thenames and addresses of three individuals who may becontacted in reference to your professional abilities.

Director of Scientific, Academic and ManagerialAppointments, National Defence Headquarters, Ottawa,Ontario Canada KIA OK2. Attention: DSAMA 3-2.

We are committed to Employment Equity.

Canad'al National Defence Defense nationale

Protein BiochemistPitman-Moore, Inc., one of the fastestgrowing animal health companies in theworld today, is presently seeking aProtein Biochemist for its R&D Techni-cal Center located in Terre Haute,Indiana.The person we seek should have an MS.degree in protein biochemistry orequivalent laboratory experience. Theposition requires working knowledgeand experience in preparation of proteindigests, HPLC separation of proteinsand peptides, and interpretation of tryp-tic peptide maps. Knowledge of proteinsequencing (ABI 477A and ABI 473) andamino acid analysis is also desirable. Theposition also requires excellent verbaland written communication skills.

As a member of the Bioanalytical Re-search Section, this individual will join adynamic research group that is solvingproblems related to biotechnology, drugdelivery, and new product development.Pitman-Moore offers a highly competi-tive compensation and benefits package.Those interested in receiving confiden-tial consideration for this position shouldforward their resume and salary expec-tations to the attention of Mr. M. G. Ray,Pitman-Moore, Inc.P.O.Box 207Terre Haute, IN 47808.

PITMAN-MOORE, INC.An Equal Opportunity Employer

)PiftmanuMoow

Molecular GeneticsSenior Scientist

Crop Genetics International, a leadingagricultural biotechnology company lo-cated in Maryland close to Washington,D. C. and Baltimore, has an opening inthe Bacterial Molecular Biology Group.The scientist will be part of a team work-ing to develop novel delivery systemsfor microbial biopesticides. The lnCideTMapproach uses genetically engineeredbacteria, which colonize the vascularsystems of major crop plants, to deliveragents effective against plant pests.

The successful candidate will have aPh.D. in Molecular Biology, Microbiol-ogy or Biochemistry, with experience inthe regulation of gene expression usingrecombinant DNA technology. Experi-ence in bacterial physiology and/or non-conventional bacteria is desirable.

To apply, forward a curriculum vitae in

confidence and the names of threeprofessional references to Dept. MG8.

<'1 >N Crop GeneticsInternational

Dept. MG87170 Standard DriveHanover, MD 21076

An Equal Opportunity Employer I

-.W

ff

POSITIONS OPEN

HUMAN MOLECULAR GENETICSPOSTDOCTORAL POSMON. Opportunity to

join an active research group involved with the cloningand analysis of the human fragile X site; the isolation ofcandidate genes for X-linked genetic diseases; and thehigh resolution genomic analysis of human Xq28. Dem-onstrated ability in gene doning chromosome walkingcDNA library construction, and/or human linkage ana

yses is highly desirable.Send curnculum vitae, reprints, other supporting doc-

uments, and three letters of reference to: Dr. Stephen T.Warren, Department of Biochemistry, Rollins Re-search Center, Emory University School ofMedicine,Atlanta, GA 30322. Emory University is an AffirmativeAction/Equal Opportunity Employer.

UNIVERSITY OF WISCONSIN-MADISONPOSTDOCTORAL RESEARCH

Opportunity for recent Ph.D. with training in molec-ular biology to collaborate in NIH-supported studies onvirulence gene expression in the pathogenic Africantrypanosomes. Support for up to 5 years; position openimmediately. Send letter of inquiry and copy of curncu-lum vitae to:

Dr. John M. MansfieldLaboratory of Immunology

Department of Veterinary Science1655 Linden Drive

University of WisconsinMadison, WI 53706MICROBIOLOGISTS

POSTDOCTORAL/RESEARCH SCIENTIST.Geo-Microbial Technologies, Inc. (GMT), an estab-lished, independent research company, seeks qualifiedPh.D. level microbiologists at both postdoctoral andresearch scientist levels. Experience in microbialgeochemistry, environmental microbiology, and/or phys-iology is desirable. Located in Tulsa area, GMT offers theopportunity to join an existing research team and gener-ate independent research in a well-equipped researchenvironment. For immediate consideration, please sendresume to: D. C. Hitzman, Geo-MicrobialTechnolo-gies, Inc., P.O. Box 132, Ochelata, OK 74051.

RESEARCH ASSOCIATE (POSTDOCTORAL).Genetic and metabolic regulation of deoxyribonucleotideand DNA synthesis in mammalian cells, in the Depart-ment of Biochemistry and Biophysics at Oregon tate

University (OSU), Corvallis, Oregon. Starting date:around 1 January 1991. Ph.D. in biochemistry or relatedfield. Experience with cell culture, HPLC, radioisotopes,and enzymology desired. Send complete curriculum vi-tae, copies of recent publications, and names of threereferences to: Dr. Christopher K. Mathews, Depart-ment of Biochemistry and Biophysics, Oregon StateUniversity, Weniger 535, Corvallis, OR 97331-6503. Salary range: $19,000 to $22,000. Applicationsaccepted through 15 October 1990. OSUisanAffimativeAction/Equal Opportunity Employer and complies with Section504 ofthe Rehabilitation Act of 1973. OSU is sensitve to theneeds ofdual-career couples.

UNIVERSITY OF MIAMIDEPARTMENT OF RADIATION ONCOLOGYThe Department ofRadiation Oncology has an imme-

diate opening for an innovative, interactive junior levelscientist (RESEARCH ASSOCIATE, POSTDOC-TORAL ASSOCIATE, or RESEARCH INSTRUC-TOR/ASSISTANT PROFESSOR (nontenure track)with a background in radiation biology (hypoxic cellsensitisers) cytokine biology (microvascular physiology),and/or experimental therapeutics (radiation-drug interac-tions) to join an interdisciplinary group investigatingcytokine-mediated microvascular injuries in solid tumors.A relevant Ph.D. is required. Preference will be given tocandidates who have demonstrated productivity and a

strong potential to develop a rigorous research programand outside funding. Salary and appointment will de-pend on experience and qualifications. Send curriculumvitae, a short statement of research interests, and thenames, telephone numbers, and addresses of three refer-ences to: Dr. Paul G. Braunschweiger, Director, Ex-

perimental Radiation Oncology Program, Depart-

ment of Radiation Oncology (D-31), University of

Miami School ofMedicine, P.o. Box 016960, Miami,FL 33101. Tdephone: 305-549-7885. FAX: 305-545-7884. The University of Miami is an Equal

Opportunity/AfirmativeAction Employer.

1072

RESEARCH ASSOCIATE, POSTDOCTORAL.To investigate the structure, regulation of expression,and function ofmicrotubule-associated proteins (MAPs).Experience in the biochemical purification and cDNAcloning of mammalian MAPs is essential. Send curricu-lim vitae and three references to: Professor NicholasCowan, Department ofBiochemistry, New York Uni-versity Medical Center, 550 First Avenue, New York,NY 10016. An Equal Opportunity Employer, M/F.

RESEARCH ASSOCIATEIN MOLECULAR VIROLOGY

The Infectious Diseases Division, Department ofMed-icine, Jefferson Medical College, Philadelphia, Pennsyl-vania, invites applications for the above position. Candi-dates require doctorate and experience in molecularvirology. Laboratory to be developed will focus onmolecular retrovirology. Position immediately available.Faculty rank to be determined by credentials.Forward curriculum vitae and ten references to: Dr.

Roger J. Pomerantz, Director, Division of InfectiousDiseases, Department ofMedicine, Jefferson MedicalCoil, 1025 Walnut Street, Philadelphia, PA19107. AjlrmativeAction/Equal Opportunity Employer.

RESEARCH ASSOCIATE. To assist in study ofbehavioral treatment of transient myocardial ischemia.M.D. and 3 years of experience in cardiology. To per-form exercise stress testing, psychometric testing, physical examinations, ambulatory ECG monitonng, dataentry. Experience with MUGA desirable. Salary:$21,000 ptus fringe benefits; 40 hours per week. Applto: Employment Security Commission, 516 NoMMangum Street, Durham,NC 27701 or your local JobService Office. Refer to: Job Order # NC3000159,DOT Code 090.227-010.

RESEARCH ASSOCIATEPosition available for a research associate at the Uni-

versity of South Florida, Tampa, Florida.Applications are invited for a molecular biologist (or

related field) with experience in cloning, gene probedevelopment, and PCR to conduct research oncryptosporidium and water-borne disease.

Qualifications: Ph.D. in molecular biology or relatedfield with erience in the isolation and aTysis ofDNAand RNA, cloning, gene probe development, and PCR.The individual mustave hands-on experience with mostof the common molecular methods.Two-year funding; full-time, 12-month appointment.

Salary range: $18,5l00 to $22,500 with benefits.Application deadline: 28 September 1990.Send curriculum vitae and three letters of reference to:

Dr. Joan RoseUniversity of South FloridaCollege of Publc Health

13301 Bruce B.Downs Boulevard, MHH 104Tampa, FL 33612

the University of South Florida is an Affirmative ActiorVEqual Opportunity Institution.

ENVIRONMENTAL PLANT PHYSIOLOGISTUNIVERSITY OF CALIFORNIA

RIVERSIDEA position is available for an environmental plant

physiologist at the Statewide Air Pollution ResearchCenter (SAPRC), University ofCalifornia, Riverside, onor after 1 November 1990. The position will be on afiscal-year basis, at the ASSISTANT RESEARCHPLANT PHYSIOLOGIST level. First-year appoint-ment will be fully supported by SAPRC; m subsequentyears part of the salary will come from grants andcontracts. Responsibilities indude cooperating in currentprograms of research on effects of air pollution on cropplants, native vegetation, and/or forest trees. The success-ful applicant will be expected to submit proposals fornew projects. Applicants must have a Ph.D. in plantphysiology or a related field; experience in environmentalphysiology, including fieldwork; and good organizationand communication skills. Send letter of application,curriculum vitae, statement of research interest, tran-scripts, and have three letters ofrecommendation sent to:Dr. Patrick McCool, Chair, Search Committee, State-wide Air Pollution Research Center, University ofCalifornia, Riverside, CA 92521. Application deadlineis 30 September 1990. The Uniesity ofCaltfomia, Riv-erside, is an Afirmative Action/Equal Opportunity Employer.Minorities and women are encouraged to apply.

RESEARCH ASSOCIATE. For university in cen-tral Ohio. Designs, executes, and controls laboratoryresearch project examining hormonal regulation of geneexpression in developing chicken retina. Develops newresearch methodologies to study gene expression in theretina; authors pub ications detailing the experimentalfindings. Assists in the writing of grant proposals and theacquisition of support from outside agencies. No expe-rience reqcuired in the job described but applicants willqualify with the following: Ph.D. in microbiology ormolecular biology and 2 years ofresearch experience withDNA sequencing, polymerase chain reaction, proteinpurification, expression vector construction, transfectionmethodologies, assays of reporter gene expression, his-tology and microscopy, and the cell biology of primaryand explant and organ culture. At least two scholarlypublications in the field. Experience can be gained con-current with earning degree. Forty hours per week, 8a.m. to 5 p.m., Monday to Friday; $24,840 per year.Must have proofoflgal authority to work penrnnently in theUnited States. Send resume in duplicate (no calls) to: C.Bussard, JO# 1260208, Ohio Bureau of Employ-ment Services, P.O. Box 1618, Columbus, OH 43216.

RESEARCH ASSOCIATE/HEMATOLOGIC ON-COLOGY. For university in southwestem Ohio. Perform-ing density cut on human blood and bone marrow samples.Use ofmonodonal antibodies to study cell cyde kinetics ofleukemias and solid tumors. Studying DNA damage andrepair induced by chemotherapy using immunohis-tochemical techniques. Autoradiography on tissue samplescontaining radioisotopes. Studies involving proliferation anddifferenciation in neoplastic cells. Use ofFeulgen reaction toquantitte the content ofDNA in diffHrent types of cancercells and corldatng it with clinical and histopathologicaldcracteristics ofthe tumor. Supervision and training ofthejunior researdc assistants. Job requires M.B.B.S. or M.D. inmedicne and 1 month of experience as research assistntKnowledge ofthe following areas as evidenced by at least 1month of research experience: (i) double labeling ofhumanlecukemic cells using two specific DNA probes (BrdU and3HTdr); (ii) use of a computeized image analysis system(QUANTIMET 520) for calculating the ploidy of cancercells; (iii) calculating the growth fraction of leukemia usingmonodonal antibodies to P145 and 5C2; (iv) use of DataAnalysis and Display System (DADS 560); and (v) immu-nohiStDcheincaly dU single-stranded DNA damageinduced by chemotherapy, utilizing antithymidine antibody(MoAb20B7). Forty hours per week; 8:00 a.m. to 5:00p.m. Salary: $25,000 per year. Must have proof of lgalauthwritytoworkpemanendyin the UnitedStates. Sendr6surmein duplicate (no calls) to: J. Davies, JO#1099724, OhioBureau of Employment Servkes, P.O. Box 1618, Co-hlmbus, OH 43216. An Equal Opportunity/AffilnatveAcion Employer.

AQUATIC BIOCHEMICAL TOXICOLOGY.Two positions: RESEARCH ASSOCIATE (Ph.D.required) and RESEARCH TECHNICIAN (B.S. re-quired, M.D. preferred). Research activities indude xe-nobiotic metabolism, glutathione metabolism, free radi-cal biology, genotoxicology, and relevant applications asbiomarkers, in aquatic fiekd studies. Expertise in analyti-cal chemistry and biochemistry, aquaculture, and/or fieldresearch sought. Send curriculum vitae and names ofthree references to: Dr. Richard T. Di Giulio, Ecotox-icology Laboratory, School of Forestry and Environ-mental Studies, Duke University, Durham, NC27706. Duke University is an Equal Opporunity/Affr-mative Action Employer.

Department of Clinical Pathology and DiagnosticMedicine, East Carolina University School of Medicine.RESEARCH TECHNICIAN m. The Department ofClinical Pathology and Diagnostic Medicine is seeking aresearch technician for the Molecular ImmunopathologyLaboratory. This person will be responsible for testdevelopment and research utilizing a wide variety offlowcytometric and cellular immunologic techniques. Therewill be dose interaction with medical technologists andwith other research technicians performing image analy-sis, gene doning, and recombinant DNA techniques.The candidate should have a master's degree and/orexperience in flow cytometric DNA analysis, immu-nophenotypic analysis, and cell function analysis. EastCarolina University School of Medicine is located in apleasant community near the coast ofNorth Carolina andoffers a competitive salary and excellent benefits. Forconsideration, please submit detailed resume to: Person-nel Depar et, ast Carolina University, Greenville,NC 27834 eAio Opportnity Employer.

SCIENCE, VOL. 249

POSITIONS OPEN POSITIONS OPEN

U.S. DEPARTMENTOF ENERGY

African Dissertation Internship Awards OSTGRADUATEDoctoral students from sub-Saharan Africa are invit- | ?RESEARCH PROGRAMS

ed to apply to The Rockefeller Foundation for disserta-tion research support. The program enables Ph.D. stu-dents enrolled in U.S. and Canadian universities to areturn to Africa for extensive field research in areas Toxicology Engineeringrelevant to economic development or poverty alleviation. Fossil Energy Physical SciencesPriority is given to research topics in the fields of Hazardous Wastes Environmental Sciencesagriculture, health and life sciences, but other proposals Artificial Intelligence Life Sciencesare welcome. Computer Sciences Risk Analysis

Applicants are responsible for arranging affiliation |* Research at national laboratorieswith an African institution able to provide needed re- * Stipends $20,000 - $41,000 depending on degree,search support, such as laboratory facilities, access to . .study sites, and technical advice. The candidate's facul- Recentgradumatedegareety advisor, the host institution in Africa, and the agency U.S. citizens or PRAs eligiblewith primary responsibility for financing the student'sgraduate work must all send letters of endorsement.

Information and applications:Deadlines for applications are October 1, 1990 and

March 1, 1991. Candidates should apply well in advance Postgraduate Research Programsof the expected field work starting date. 0 0 Science/Engineering Education Division

For a full description of the competition and the Oak Ridge Associated Universitiesapplication requirements, write to: African Dissertation ( P.O. Box 117Internship Awards, The Rockefeller Foundation, 1133 Oak Ridge, TN 37831-0117Avenue of the Americas, New York, NY 10036 USA. (615) 576-3190

r= .,''''---- -pp .... '''''--.--1 d E i % t

Ph.D. CLINICAL IbstDoctoral POSTDOCTORALCHEMIST Research POSITION

Drug Safety Division Pbsition Position available for an individualWyeth-Ayerst Laboratories, a major with a Ph.D. in cell biology, biochem-division of a Fortune 100 corporation,isr,ophilgywtexrenenhas an immediate opening for a Ph.D.level HEMATOLOGY- istry,orphysiologywithexperienceinClinical Chemist to supervise a modern, cell culture. The successful applicantwell-equipped clinical laboratory at our OIN OL UGT will be involved in research into theDrug Safety testing facility in upstateNew York. mThrombosis olecular mechanisms throughApplicants for this position should possess which physical forces, generated dur-previous experience with the Hematology Research Center ing cellular deformation, influenceClinical Chemistry and Biochemistry of the cellular biochemistry. Research willcommon laboratory species, and with the Position cediately availladaptation of human testing proceduresand Position Immediately available focus on the molecular structures in-as tools for the rapid interpretation ofclinical for post-doctoral research volved in regulation of mechanically-results. The successful candidate will work fellow. Ph.D. or M.D. with expe- sensitive adenylate cyclase and Na+/on a cooperative basis with Ph.D. level rienceinmolecularand/orcellToxicologists, Pathologists and Pharma- biology will participate n

H+ antiporter activities during volumecologists, providing input regarding the biologyon willoparticipatesinlsignificance of the clinical results and studies of adhesion proteins expansion and compression, as welldeveloping strategies to further elucidate and receptors on platelets and as during cell spreading followingthe possible mechanism of drug toxicity. vascular cells. extracellular matrix attachment.In addition to an excellent starting salary,liberal benefits package and opportunities Send CV to: Roy L. Silver- Competitive salary and fringe benefitsfor professional growth, we offer achoice stein, M.D., Division of Hema- are available. Please send CV andlocation between the foothills of the Adiron-tooyOclg,CRELthreenames or letters of reference to:dack Mountains and the shores of Lake tology-Oncology, CORNELLChamplain; areas boasting 4-seasonrecre- UNIVERSITY MEDICAL COL- Dr. Peter A. Watsonational activities and leading NY and VT LEGE, 1300 York Avenue, New Ws eter f archuniversities. To express interest, forward York, New York 10021. An Equal Weis Center for Researchresume with salary requirements to: Mr. York, Cli.icGary D. Wagoner, Wyeth-AyerstLabora- Opportunity/AffirmativeAction Danville, PA 17822tories, 64 Maple Street, Rouses Point, Employer.NY 12979. Equal Opportunity Employer M/F/HN

CORNELL lUNIVERSITY ---v Ge|s|nger

KnO AGENCK1'=iE PLA5E MEDICAL ~ 199Equal Opportunity Employer M/F/H/V COLL_E_G_E'_____________ibzzzzzzzz~~ I__________________

THE ROCKEFELLER FOUNDATION I

POSITIONS OPEN POSITIONS OPEN ANNOUNCEMENTS

ASSOCIATE RESEARCH SCIENTIST. Positionavailable to study biochemical basis for antiviral activityof compounds developed in our laboratory. Experiencein enzymology, nucleic acid biochemistry, virology, andcell culture is desirable. Salary negotiable. Send r6sumeand three letters of reference to: Dr. W. Prusoff, De-partment ofPharmacology, Yale University School ofMedicine, 333 Cedar Street, New Haven, CT 06510.An Equal Opportunity/Affirmative Action Employer.

Associate Professor of Medicine (RESEARCH PO-SMTION). To be responsible for supervision of researchfellows and graduate students involved in research of thebiology of hepatitis B virus. Specific duties including:cloning ofDNA and cDNA; in vitro expression ofDNAand cDNA; molecular hybridization analyses (spot blot,Southern blot, Northern blot, and in situ hybridization),including radiolabeling of DNA, RNA, and oligonucle-otides; polymerase chain reaction, DNA sequence anal-yses; isolation of propagation of mononuclear cells fromhuman blood; transient and stable transfection of mam-malian cells; and patient selection and patient care forimmunotherapy of hepatocellular carcinoma and othermalignancies. Candidate must possess M.D. in medicinetogether with 3 years in position offered or 3 years as amedical researcher involved in molecular biology ofhepatitus B virus. Must also possess demonstrated exper-tise in the design and execution of animal experiments,including operative skills; demonstrated expertise in thedetection of viral infections at the single cell level by insitu hybridization; demonstrated expertise in the evalua-tion of antiviral drugs (vitro and in vitro); knowledge ofmolecular hybridization techniques, cloning, sequencing,polymerase chain reaction, and transfection mammaliancells; knowledge ofmolecular biology, biochemistry, andhepatology. Salary: $55,000 per year for 5-day, 40+-hour work week. Send resumes to: Massachusetts De-partment of Employment and Training, Special Pro-grams Department, 19 Staniford Street, Boston, MA02114, Attention: Job Order #00694. Affirmative Ac-tion/Equal Opportunity Employer.

Assistant Professor of Medicine (RESEARCH PO-SMIION). To be responsible for classroom instruction,research, and supervision of research fellows and gradu-ate students involved in production and characterizationof monoclonal antibodies against tumor-associated anti-gens. Also responsible for supervising foreign scholarscoming for studies relating to chronic hepatitis B viralinfection and their role in the transformation of hepato-cytes to malignant phenotype; directing research onimmunotargeting of cancer with monoclonal antibodiesconjugated to cytotoxic drugs, radioisotopes, and toxins;immunohistological analysis of cancer; and developmentof gene therapy of cancer. Candidate must possess M.D.and Ph.D. in medical science or cell biology togetherwith 2 years in position offered or 2 years as a researcher.Must also possess demonstrated expertise in the molec-ular biology of hepatitis B infection including DNAcloning, sequencing, and transfection technique, experi-ence in transgenic mice; demonstrated expertise in im-munohistopathology of cancer including detailed knowl-edge of tumor pathology; demonstrated expertise innuclear medicine especially related to radioimaging andradioimmunotherapy of gastrointestinal cancer and lungcancer including conjugation of monoclonal antibodiesto drugs, radioisotope especially high energy beta emitterand toxins. Salary: $40,000 per year for 5-day, 40+-hourwork week. Send two (2) resumes to: MassachusettsDepartment of Employment and Training, SpecialPrograms Department, 19 Staniford Street, Boston,MA 02114, Attention: Job Order #00729. AfirmativeAction/Equal Opportunity Employer.

SITUATIONS WANTED

BIOCHEMIST. Ph.D. (1980). Experience; enzy-mology, enzyme immobilization and modification, reac-tor control, biomass utilization, natural products extrac-tion, bioprocessing. Seeks research position. Box 89,SCIENCE.

MICROBIOLOGIST/MOLECULAR BIOLO-GIST, M.Sc. Tissue culture, rDNA, protein gel electro-phoresis. Experience in yeast genetics and retrovirology:2 to 3 years. Box 95, SCIENCE.

M.D. Former medical director, major drug companies,25 years. Seeks fuill- or part-time employment. Regula-tory, writing, statistics, NDAs, GCP, GLP, etc. Tele-phone: 215-794-5581.

I074

RESEARCH SCIENTISTS (2). Rorer Central Re-search, a Division of Rhone-Poulenc Rorer, a worldwideethical pharmaceutical company, has immediate openingsfor two research scientist positions to perform cancerresearch focusing on the investigation of tyrosine kinasestructure/function relationship, biological control andfunction in cell growth control/somatic development,and tissue regeneration. Develop, track, and presentresults of experiments and international professionalpublications and seminars. Ph.D. in biochemistry plus 2years of hands-on experience performing research incor-porating protein chemistry, cell biology, molecular biol-ogy, and crystallography and computer programmingrelating to the field of cell growth control, oncogenes,receptor-ligand interactions, and receptor signaling;$37,000 per year. Rorer offers competitive salaries,company-paid benefits, and excellent potential for pro-fessional recognition and advancement. Please submitr6sume to: Position #INS-AH1, Rorer Central Re-search, 640 Allendale Road, King of Prussia, PA19406. Equal Opportunity Employer, MIF.

VIROLOGISTThe Yerkes Regional Primate Research Center and

Department of Pathology, Emory University, have anopening for a virologist with experience in retrovirusresearch. Candidates should have a Ph.D., D.V.M.,M.D., or equivalent and should have sufficient researchexperience to demonstrate their ability to establish anindependent research program in areas related to thepathogenesis of AIDS and related retroviruses in animalmodels. The successful applicant will also participate inongoing clinical, immunological, and pathological stud-ies with the simian immunodeficiency virus. Salary isnegotiable and is commensurate with experience. Theposition is available immediately. Letters of applicationincluding curriculum vitae, a brief statement of researchinterests, and the names of three references, should besent to: Dr. Harold McClure, Associate Director,Yerkes Primate Research Center, Emory University,Atlanta, GA 30322. Emory University is an Equal Oppor-tunity/Affirmative Awtion Employer.

ANNOUNCEMENTS

CORONARYI \i HEART DSEASE

RESEARCA PRrgam dthe

American HeakAssistanceFoundation

Grant applications for starter grants for CORO-NARY HEART DISEASE RESEARCH will be ac-cepted for 1 year with a limit of $15,000 (renewable).The deadline date for submission of applications is 30November 1990. Write to:

American Health Assistance FoundationResearch Grants Department

15825 Shady Grove Road, Suite 140Rockville, MD 20850

ANNOUNCEMENT ANDCALL FOR POSTER ABSTRACTSTHE FRANK K. KELEMENMEMORIAL SYMPOSIUM:THE MOLECULAR BASIS

OF SIGNAL TRANSDUCTION12 to 13 November 1990; Hyatt Cherry Hill, Cherry

Hill, New Jersey.Organized by the Coriell Institute of Medical Re-

search, Camden, New Jersey, in honor of Dr. StanleyCohen of Vanderbilt University. Other speakers include:Janice Buss, Tom Curran, Jackson Gibbs, Ed Harlow,David Livingston, Roger Perlmutter, Haruo Saito, Jo-seph Schiessinger, Richard Stanley, and George Todaro.To receive conference registration and abstract submis-

sion information, please call or write to: Dr. SubalBishayee, Coriell Institute for Medical Research, 401Haddon Avenue, Camden, NJ 08103. Telephone:609-757-9749.

YOUR PERSONNEL PLACEMENT ADin our line classified columns

can be boxed for higher visibility.Call SCIENCE at 202-326-6555 for details.

NAnIONALGLAucoMARESEARCHAPrmam of the

Amerian HeahAssiance Foundaiion

Grant applications for NATIONAL GLAUCOMARESEARCH will be accepted for 1 year, $25,000maximum, renewable. The deadline date for submissionof applications is 30 November 1990. Write to:

American Health Assistance FoundationResearch Grants Department

15825 Shady Grove Road, Suite 140Rockville, MD 20850FELLOWSHIPS

A limited number of postdoctoral and predoctoralfellowships are available from Sigma Delta Epsilon-Graduate Women in Science, Inc. Applications fromwomen are particularly encouraged.

Fellowships are for $1000 to $4000.A total Of $20,000 is available.Deadline is 1 December 1990.For additional information and application forms:

Sigma Delta Epsilon-Graduate Womenin Science, Inc.P.O. Box 4748

Ithaca, NY 14852WORKSHOP ON GENERAL POPULATION

EXPOSURES TO GASOLINESponsored by the American Petroleum Institute, U.S.

Environmental Protection Agency, Motor Vehicle Man-ufacturers Association, Northeast States for CoordinatedAir Use Management (NESCAUM), National Petro-leum Refinery Association, Western States PetroleumAssociation, Health Effects Institute (HEI), and theCanadian Petroleum Products Institute (CPPI).

CALL FOR DATACALL FOR PAPERS

There is increasing debate among public health offi-cials about exposure to gasoline. A 2 1/2-day workshopis planned for 12 to 14 December 1990 in Annapolis,Maryland, to facilitate discussion among scientists, man-agers, and policymakers in the public and private sectorsabout general population exposures to gasoline or con-stituents thereof (excluding combustion products orsmog). The workshop will highlight new data on gaso-line exposures and examine new strategies for analyzingexposure. The product will be a compilation of peer-reviewed papers and an executive summary to informregulatory decision-makers as they consider possible re-duction strategies for gasoline exposures. We are seekingsubmissions ofdata (for incorporation into a backgroundpaper currently in preparation) or presentations of dataon nonoccupational gasoline exposures. Please empha-size the database avairable.

Deadline for submission of abstracts (200 to 300words) and/or data is 1 October 1990.

Registration is open; fee is $150. To submit abstractsand/or data and to obtain further information about theworkshop, contact: Dr. Karen L. Hulebak, EnvironInternational Corporation, 4350 North FairfaxDrive, Arlington, VA 22203. Telephone: 703-516-2300. FAX: 703-516-2345.

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each additional base. No additional charges.Research Genetics

SCIENCE, VOL. 249

Research AssociatesFoot-and-Mouth Disease

Plum Island Animal Disease CenterThe Center is expanding its research programs on FMD virus to include fundamental studies on thestructural basis of immunogenicity and virus-cell interactions. These studies will be conducted by anew multidisciplinary group in conjunction with Dr. Fred Brown FRS, Yale University School of Medi-cine. The group, which has strong base funding, will be located in well-equipped laboratories in theCenter's high security animal biocontainment facilities.

Postdoctoral Research Associate positions are available in protein crystallography, molecular virology,and immunology and offer a unique and highly productive opportunity.Four positions are open in the following areas:

1. Analysis by X-ray crystallography of the structure of the virus and its reaction with antibodiesand cell receptors. The Center has its own X-ray crystallography facility. Dr. J. Hogle, ScrippsClinic and Research Foundation, is collaborating in these studies.2. Analysis of the structural basis of antigenic specificity of immunogenic peptides by nuclearmagnetic resonance and circular dichroism. This work will be a collaboration with ProfessorW.A. Gibbons and Dr. P. Mascagni, University of London, England.3. Study of the molecular basis of the interaction between the virus and cell receptors.4. Study of the immune response to synthetic peptides and recombinant vaccines.

The Center is situated off the northeast tip of Long Island, New York. USDA ferry services to OrientPoint, NY and Old Saybrook, CT offer a choice of living on Long Island or in Connecticut. Close collabo-rations are being developed with research institutions in the area, including: Yale and Tufts Universities,the University of Connecticut and the State University of New York at Stony Brook.

Appointments are for two or three years from December 1, 1990 (or by arrangement), and, based on quali-fications, will be at the GS-11 (approximately $30K/year) or GS-12 level (approximately $36K/year).Successful candidates must have obtained a PhD or equivalent degree in a relevant discipline within thelast 3 years. Individuals with experience in picornaviruses or protein crystallography are particularly en-couraged to apply. Applicants should send a curriculum vitae marked ON053 along with the names andaddresses of three references to:

Dr. P.W. MasonUSDA-ARS, Plum Island Animal Disease CenterP.O. Box 848Greenport, LI, NY 11944

Applications must be received before November 1, 1990

ARS IS AN EQUALOPPORTUNITYEMPLOYERWOMENAND MINORITIES ARE ENCOURAGED TO APPLY

United States Department of AgricultureAgricuftural Research Service

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