3/11/15 11:40 AMSystolic B.P > (proportional) > Cardiac Output CODiastolic B.P > (proportional) >Total Peripheral Resistance TPR

MEAN ARTERIAL PRESSURE:Average of systolic and diastolic pressure

40 mmHg (extra in systole) is divided by 3 = 13 mmHg = MEAN ARTERIAL PRESSUREwhy 3? = because systole is 1/3 and diastole 2/3!!!

MEAN ARTERIAL PRESSURE VS MEAN SYSTEMIC PRESSUREMAP > only on ARTERIAL site = 100 mmHg (healthy one)Arteries!!! From heart to arteriolesMSP > only on SYSTEMIC site = 6.5 mmHgVenous + capillary + arterioles = pressure maintained in systemic circulation when there is not cardiac output When heart doesnt workVENOUS RETURN > from tissues to the heart

BLOOD PRESSURE>

CO: (SYSTOLE) depends on stroke volume SV & Heart Rate HRSTROKE VOLUME SV:Preload: blood in ventricle before contractionEnd diastolic volume / end diastolic pressure (how much it stretches before contraction)Venous Return which depends on RAP (right atrial pressure)FILLING PRESSURE1. Venomotor tone2. Blood volumeFILLING TIMEWhen heart beats are very very fast! The filling will be less; therefore, E.D.V will be less and BP lessContractility If there is less C > SV is less > CO is less > BP is lessAfterLoad > TPRIf I give a arteriole dialator > TPR will be less > afterload will be less > TPR (TOTAL PERIPHERAL RESISTANCE) > DIASTOLE:

MAP = CO x TPR (these 2 are interdependant) if CO (up) > TPR (down) and MAP (UP) or viceversa

REGULATION OF BLOOD PRESSURESHORT TERM (neurological)LONG TERM (Renin Angiotensin Aldosterone Axis)

SHORT TERM>Neurological RgLONG TERM >

BLOOD PRESSURE REGULATION3/11/15 11:40 AM

3/11/15 11:40 AM