Biostatistics and Bioinformatics Shared Resource (BBSR)Dr. Christopher LoffredoCo Director Kepher Makambi, PhDCo Director

Statistical analysis Clinical Trials Support

Bioinformatics

BBSR Services

Biostatistics and Bioinformatics provide:

• Support for data analysis from basic science, clinical, and population science research projects.

• Support for planning, analysis, and monitoring of clinical trials.

• Support for grant proposals, including power and sample size estimation, and data analysis planning.

Examples of Science Supported by the BBSR

Microarray analysis

Proteomic and

Metabolomic analysis

Models of Cancer Risk

Efficacy of randomized treatment

Forecasting of cancer

trends

Hardware Resources•Dell desktop-class computers: Windows and Linux OS

•Central processing and file storage servers: 64bit AMD Opterons running RedHat Enterprise

•Quad-core computer: dedicated to web applications

•Development servers: 2 Quad-Core Intel CPUs, using CentOS 5.0 Linux to support Oracle 11g, MySQL 5.0, PostgreSQL, a Web server (Apache), an application server (JBOSS), and development tools.

All applications are scalable to meet the needs of users

Software Resources

•General: SAS, GAUSS, MATHEMATICA, STATISTICA, StatXact, R, MATLAB, SPSS

•Experimental Design: Simon’s Phase II, PS, NQuery, StPlan, Bayesian Plans for Phase II Trials, Power and Precision

•Specialized Packages: CART, Mplus

Software Resources

•Bioinformatics: Bioconductor, DCHIP, PDQuest, PAUP, BRB-Array Tools

•Database: MySQL, Oracle, Oracle Jdeveloper

•Programming: Java, IMSL, Perl, PHP, VB/ASP, Weka, C, C++

•Optimization: MOZEK

For More Information

Contact Christopher Loffredo,PhD, DirectorCAL9@georgetown.edu or

Kepher Makambi, PhDCo Directorkhm33@georgetown.edu

Caroline Wu ctw26@georgetown.edu

http://lombardi.georgetown.edu/research/sharedresources/bbsr/index.html

Shared Resources are partially supported by the Georgetown Howard University Center for Clinical and Translational Studies (GHUCCTS) 1UL1RR031975-01

  In your publications, remember to mention support provided from the GHUCCTS.