Biopharmaceutical Filtration Solutions · filters. provides professional assistances to liquid and...

www.anowfilter.com

Biopharmaceutical

Filtration Solutions

Hangzhou Anow Microfiltraion Co.,Ltd.Office：Room 901-903, Central Building, No.271, Hushu South Road, Hangzhou, China

Plant: Qingming Bridge, Xindeng Industrial Zone, Fuyang, Hangzhou, China

Tel: +86-571-883-70389

Fax: +86-571-883-70399

Website: www.anowfilter.com

E-mail: [email protected]

Making the Filtration Better

Located in Hangzhou, 's plant covers a

2production workshop area of 6000 m , with 3000

2m area meeting the GMP requirements for

2 5manufacturing of medical devices, 600 m 10 -

2class cleaning room and 2400 m cleaning room.

We have more than twenty lines for the

production of microporous membranes and

pleated filter cartridges, advanced inspection

tools and equipments, as well as professional

R&D Center and Validation Center. All the

membrane products are manufactured in

ISO9001:2008 certified facility with the help of

trained manpower meeting or exceeding

industry standards.

www.anowfilter.com

COMPANY INTRODUCTION

Microfiltration is a well-known filtration leader,started from 1989, who focus on research and

development of MCE, Nylon, PES, PVDF, PTFE membrane, with pore size ranging from 0.03 μm to 10

μm, as well as design and production of various pleated filter cartridges, syringe filters and capsule

filters. provides professional assistances to liquid and gas & air filtration solutions for

customers around the world in biopharmaceutical, medical, food & beverage, microelectronic,

chemistry, water treatment and laboratory applications.

In biopharmaceutical industry, products

are used in highly regulated industries for critical

applications such as sterile filtration of

pharmaceutical and biopharmaceutical

process fluids, sterility testing of aseptic drug

products, analytical sample preparation, new

drug development and so on.

has been making great efforts to improve

the quality management system during the

process of obtaining the production certificates

and registration. We help to deliver an ever

increasing portfolio of innovative products with

unique performance advantages.

www.anowfilter.com

CONTENTS

ANOW Membrane Technologies

Quality Assurance

Validation Service

Customer Support

Facilities Water

Cell Culture Media Preparation

Small Volume Parenterals (SVP)

Large Volume Parenterals (LVP)

Plasma Fractionation

Ophthalmic Solutions

Filter Cartridges

LPSL-Low Extractable and Longer Service Life Filter Cartridge with Double Layer PES Membrane

Filter Housings

Connections 66

LPSHT-Highly Asymmetric PES Filter

Cartridge for Higher Throughput Demands

LPSHV-PES Filter Cartridge for Sterile

Filtration of High Viscous Pharmacy

LPS-Single Layer Hydrophilic PES Filter

Cartridge for Final Filtration of Pharmacy

LPSD-Double Layer Hydrophilic PES

Filter Cartridge for Extremely

Demanding of Sterilizing Filtration

LPT-Hydrophobic PTFE Filter

Cartridge with Broad Chemical Compatibility

LPTA-Hydrophobic PTFE Filter

Cartridge for Sterilizing Filtration of Air/Gas

LPNN-Hydrophilic Nylon Filter

Cartridge for Sterile Filtration of

Facilities Water & API

LPTL-Hydrophilic PTFE Filter

Cartridge for Solvent Filtration

LPGF-Glass Fiber Filter Cartridge

for Prefiltration of Viscous

Pharmacy and Vaccines

Hydrophilic Nylon Membrane

Hydrophilic PES Membrane

Hydrophilic MCE Membrane

Hydrophobic PTFE Membrane

Hydrophobic PVDF Membrane

HY Stainless Steel Filter Housing for Sanitary Liquid Filtration

Series

HK Stainless Steel Filter

Housing for Gas&Air Filtration

Series

HM Sanitary Disc HolderSeries Filter

HT Titanium Filter HousingSeries

HG Sanitary In-line Liquid

and Gas Filter Housing

Series

Chemical Compatibility Guide

LPM-Hydrophilic MCE Filter

Cartridge for Prefiltration of Biologicals

LPV-Hydrophobic PVDF Filter

Cartridge with Low Protein Binding

LPP-The Most Economical PP

Filter Cartridge for Prefiltration

LPPF-The Most Efficient multi-layer

PP Filter Cartridge for Prefiltration

LPAP-Absolute PP Filter Cartridge

for Active Pharmaceutical Ingredients

Applications

Membranes

CTP Tri-Clamp Capsule Filter for

Small Volume & High

Value-added Pharmacy

CHP Hose Barb Capsule Filter

for Small Volume & High

CNP 1/4" NPT Capsule Filter for Small Volume & High Value-added Pharmacy

F5P φ50 Filter Unit

®Easiprep φ5/ Syringe Filter

φ13/φ20/φ25/φ33

Capsule Filters & Syring Filters

Located in Hangzhou, 's plant covers a

2production workshop area of 6000 m , with 3000

2m area meeting the GMP requirements for

2 5manufacturing of medical devices, 600 m 10 -

2class cleaning room and 2400 m cleaning room.

We have more than twenty lines for the

production of microporous membranes and

pleated filter cartridges, advanced inspection

tools and equipments, as well as professional

R&D Center and Validation Center. All the

membrane products are manufactured in

ISO9001:2008 certified facility with the help of

trained manpower meeting or exceeding

industry standards.

www.anowfilter.com

Microfiltration is a well-known filtration leader,started from 1989, who focus on research and

development of MCE, Nylon, PES, PVDF, PTFE membrane, with pore size ranging from 0.03 μm to 10

μm, as well as design and production of various pleated filter cartridges, syringe filters and capsule

filters. provides professional assistances to liquid and gas & air filtration solutions for

customers around the world in biopharmaceutical, medical, food & beverage, microelectronic,

chemistry, water treatment and laboratory applications.

In biopharmaceutical industry, products

are used in highly regulated industries for critical

applications such as sterile filtration of

pharmaceutical and biopharmaceutical

process fluids, sterility testing of aseptic drug

products, analytical sample preparation, new

drug development and so on.

has been making great efforts to improve

the quality management system during the

process of obtaining the production certificates

and registration. We help to deliver an ever

increasing portfolio of innovative products with

unique performance advantages.

www.anowfilter.com

CONTENTS

Quality Assurance

Validation Service

Customer Support

Facilities Water

Filter Cartridges

LPSL-Low Extractable and Longer Service Life Filter Cartridge with Double Layer PES Membrane

Filter Housings

Connections 66

LPSHT-Highly Asymmetric PES Filter

Cartridge for Higher Throughput Demands

LPSHV-PES Filter Cartridge for Sterile

Filtration of High Viscous Pharmacy

LPS-Single Layer Hydrophilic PES Filter

Cartridge for Final Filtration of Pharmacy

LPSD-Double Layer Hydrophilic PES

Filter Cartridge for Extremely

Demanding of Sterilizing Filtration

LPT-Hydrophobic PTFE Filter

Cartridge with Broad Chemical Compatibility

LPTA-Hydrophobic PTFE Filter

Cartridge for Sterilizing Filtration of Air/Gas

LPNN-Hydrophilic Nylon Filter

Cartridge for Sterile Filtration of

Facilities Water & API

LPTL-Hydrophilic PTFE Filter

Cartridge for Solvent Filtration

LPGF-Glass Fiber Filter Cartridge

for Prefiltration of Viscous

Pharmacy and Vaccines

Hydrophilic Nylon Membrane

Hydrophilic PES Membrane

Hydrophilic MCE Membrane

Hydrophobic PTFE Membrane

Hydrophobic PVDF Membrane

HY Stainless Steel Filter Housing for Sanitary Liquid Filtration

Series

HK Stainless Steel Filter

Housing for Gas&Air Filtration

Series

HM Sanitary Disc HolderSeries Filter

HT Titanium Filter HousingSeries

HG Sanitary In-line Liquid

and Gas Filter Housing

Series

LPM-Hydrophilic MCE Filter

Cartridge for Prefiltration of Biologicals

LPV-Hydrophobic PVDF Filter

Cartridge with Low Protein Binding

LPP-The Most Economical PP

Filter Cartridge for Prefiltration

LPPF-The Most Efficient multi-layer

PP Filter Cartridge for Prefiltration

LPAP-Absolute PP Filter Cartridge

for Active Pharmaceutical Ingredients

Applications

Membranes

CTP Tri-Clamp Capsule Filter for

Small Volume & High

CHP Hose Barb Capsule Filter

for Small Volume & High

CNP 1/4" NPT Capsule Filter for Small Volume & High Value-added Pharmacy

®Easiprep φ5/ Syringe Filter

φ13/φ20/φ25/φ33

Capsule Filters & Syring Filters

www.anowfilter.com www.anowfilter.com

membrane products are well designed with built-in quality assurance. We introduce the most stringent Quality

Management System covering careful selection of raw material, validated manufacturing process, quality control

and assurance and so on. All this is to ensure consistently offer high quality products for our customers.

brings more than 26 years of

experience in membrane technology to the

biopharmaceutical, medical, laboratory, food

& beverage, microelectronic and chemical

applications. And we have been continuously

working to provide customized filtration solutions

with high quality.

Quality Assurance

ISO Certified

Complete Traceability

Certificate of Products

Deep Characterization and Certification

membrane products are well designed with built-in quality assurance. We introduce the most stringent Quality

Management System covering careful selection of raw material, validated manufacturing process, quality control

and assurance and so on. All this is to ensure consistently offer high quality products for our customers.

brings more than 26 years of

experience in membrane technology to the

biopharmaceutical, medical, laboratory, food

& beverage, microelectronic and chemical

applications. And we have been continuously

working to provide customized filtration solutions

with high quality.

Quality Assurance

ISO Certified

Complete Traceability

Certificate of Products

Deep Characterization and Certification

Integrity Test

Confirm the correlation of integrity test values which

were gotten under both standard and process fluid

conditions.

Bacterial Challenge Test

According to ASTM F838 methodology, testify bacterial

retention capability of membrane or filter at a minimum

7 2concentration of 10 cfu/cm of filter surface area,

under simulated process conditions.

Chemical Compatibility

Ensure the compatibility of filter and process fluid.

Ensure the reliability of filter in process condition.

Provide supportive data for filter selection.

Extractables

Determine all the chemical components that migrate

from membranes or filters into a drug product or process

fluid in proper solvents in worst case. It indicates

maximum possibility of chemical components migrating

from membranes or filters.

Adsorption

Measure the adsorption ability of filter media in fluid

filtration process.

Multi-use Validation

Confirm retention capacity of cartridges in normal

process or simulated conditions after multiple uses.

Filter Cleaning

Provide the filter cleaning method for the specific fluid

filtration.

Sterilizing filtration for pharmaceutical liquids is indispensable and critically important in aseptic manufacturing. It is the

process of removing bioburden, particles and bacterial endotoxins from a fluid stream without adversely affecting drug

product quality. With years of experiences in pharmaceutical research, more details and supportive data were found

that the sterilizing filtration is a high risk process, whose risk is next only to that of sterilizing making and filling. Only if it gets

through with validation, we could be sure of the compatibility, extractables/leacheables and adsorption, then to confirm the

reliability of sterilizing filtration. Besides, GMP, FDA and PDA described the requirements for sterilizing filtration validation

under specific conditions.

can offer validation services, designed to the unique needs of each customer's fluid and set of process conditions,

and help to prepare normative documents to achieve regulatory compliance. These include the following items:

Validation Service

has always been working to support your

applications and welcomes the opportunity to assist

you in the education of your staff.

Customer Support

Customized Filtration Solutions

We offer customized solutions for complex

filtration problems. And we will help you in finding

suitable solutions with minimizing filtration cost.

Filtration System Design

offers technical support for your selection of

filter materials, cartridge length, filter housing and

performing throughput studies to optimize filter sizing

with cost-effective filtration system.

Installation and Operation Training

filtration specialists are available to assist

customers with theory training and hands-on

installation and operation training.

Technical Seminars

Technical seminars at customer’s location are

organized to help the users better understand

standard operation procedures of products, thus

to improve the performance and to extend the

service life of products. Besides, technical exchanges

can also be helpful for users to select the optimized

solutions for their applications.

ANOW offers an extensive range of support including

validation, filtration education, installation training,

and other experience sharing that customers need.

Integrity Test

Confirm the correlation of integrity test values which

were gotten under both standard and process fluid

conditions.

Bacterial Challenge Test

According to ASTM F838 methodology, testify bacterial

retention capability of membrane or filter at a minimum

7 2concentration of 10 cfu/cm of filter surface area,

under simulated process conditions.

Chemical Compatibility

Ensure the compatibility of filter and process fluid.

Ensure the reliability of filter in process condition.

Provide supportive data for filter selection.

Extractables

Determine all the chemical components that migrate

from membranes or filters into a drug product or process

fluid in proper solvents in worst case. It indicates

maximum possibility of chemical components migrating

from membranes or filters.

Adsorption

Measure the adsorption ability of filter media in fluid

filtration process.

Multi-use Validation

Confirm retention capacity of cartridges in normal

process or simulated conditions after multiple uses.

Filter Cleaning

Provide the filter cleaning method for the specific fluid

filtration.

Sterilizing filtration for pharmaceutical liquids is indispensable and critically important in aseptic manufacturing. It is the

process of removing bioburden, particles and bacterial endotoxins from a fluid stream without adversely affecting drug

product quality. With years of experiences in pharmaceutical research, more details and supportive data were found

that the sterilizing filtration is a high risk process, whose risk is next only to that of sterilizing making and filling. Only if it gets

through with validation, we could be sure of the compatibility, extractables/leacheables and adsorption, then to confirm the

reliability of sterilizing filtration. Besides, GMP, FDA and PDA described the requirements for sterilizing filtration validation

under specific conditions.

can offer validation services, designed to the unique needs of each customer's fluid and set of process conditions,

and help to prepare normative documents to achieve regulatory compliance. These include the following items:

Validation Service

has always been working to support your

applications and welcomes the opportunity to assist

you in the education of your staff.

Customer Support

Customized Filtration Solutions

We offer customized solutions for complex

filtration problems. And we will help you in finding

suitable solutions with minimizing filtration cost.

Filtration System Design

offers technical support for your selection of

filter materials, cartridge length, filter housing and

performing throughput studies to optimize filter sizing

with cost-effective filtration system.

Installation and Operation Training

filtration specialists are available to assist

customers with theory training and hands-on

installation and operation training.

Technical Seminars

Technical seminars at customer’s location are

organized to help the users better understand

standard operation procedures of products, thus

to improve the performance and to extend the

service life of products. Besides, technical exchanges

can also be helpful for users to select the optimized

solutions for their applications.

ANOW offers an extensive range of support including

validation, filtration education, installation training,

and other experience sharing that customers need.

Cells used to produce therapeutic proteins should have a precise nutritional balance to support their reproduction

and growth. These nutrients are provided by culture media, which must be sterile. Final sterilizing filtration should assure

the removal of bacteria and mycoplasma from culture media containing animal derived components.

Culture media are then stored in a fermentation vessel or bioreactor after bulk preparation and sterilizing filtration.

Prefilters are used to remove most particulate and colloidal contaminants from culture media in order to extend the

service life of final sterilizing filters.

Separation Goals

www.anowfilter.com7

● Prefiltration

Remove colloids, lipids and particles

● Sterilizing filtration

Remove bacteria and mycoplasma

Application Requirements

● Prefiltration should remove particulate and colloidal contaminants effectively and not hinder the bypass of important

components.

● Prefilters must have high flow rates and consistent high throughputs in order to finish the separating process timely and

economically. Furthermore, the filtration system should be compatible with differences, resulting from batch to batch

component variability.

Recommendation

Filtration Step Recommendation

Prefiltration LPM, LPGF

Sterile venting LPTA

Final filtration LPS, LPSD, LPSL

Prefiltration Sterile Filtration Sterile Holding Tank Final Filtration Bioreactor Fermentor

SterileVenting SterileVenting

Mix Tank

Media Powder

www.anowfilter.com 8

Facilities Water

Pharmaceutical grade water is defined as feed water common to process systems such as washers, autoclaves

or WFI systems. Since water source varies widely in quality, only appropriate filtration systems can ensure the

production to be effective, safe and successful.

Filtration is just one step of the manufacturing process of pharmaceutical grade water. Other steps may result in

the increasing of particles, for both resin and activated carbon beds could produce powder.

Separation Goals

● Prefiltration

Remove colloidal and particulate contaminants to extend the service life of final filters.

● Final Filtration

Remove particles, microorganisms and endotoxins to meet the requirements of FDA and other international standards.

● Prefilters must remove most particulate and colloidal contaminants effectively, and have high dirt-holding

capacity, and keep high flow rates and high throughputs.

● Final filters must remove microorganisms and endotoxins, and keep high flow rates and high throughputs.

Prefiltration LPP, LPM, LPGF

Final filtration LPS

LPNN for removing endotoxins

Filters with positive charge have limited capacity of removing endotoxins. Once the capacity is saturated, they lose this

ability of removing endotoxins. Series connection of two filters is the solution, monitoring the endotoxins between the two

filters. When endotoxins exist in the downstream of the first filter, the second filter should replace the first one in its position.

This can make full use of filters and ensure reliable retention rate. Replacement of filters with no charge depends on pre-

setting limitation index such as maximum differential pressure, minimum flow rate and maximum life time.

Recommendation

Prefiltration Sterile Filtration Final FiltrationCompression

Point of Use

Prefiltration Sterile Filtration Sterile Holding Tank Final Filtration

SterileVenting

Endotoxin

Removal

Point of Use

Cells used to produce therapeutic proteins should have a precise nutritional balance to support their reproduction

and growth. These nutrients are provided by culture media, which must be sterile. Final sterilizing filtration should assure

the removal of bacteria and mycoplasma from culture media containing animal derived components.

Culture media are then stored in a fermentation vessel or bioreactor after bulk preparation and sterilizing filtration.

Prefilters are used to remove most particulate and colloidal contaminants from culture media in order to extend the

service life of final sterilizing filters.

Separation Goals

www.anowfilter.com7

● Prefiltration

Remove colloids, lipids and particles

Remove bacteria and mycoplasma

● Prefiltration should remove particulate and colloidal contaminants effectively and not hinder the bypass of important

components.

● Prefilters must have high flow rates and consistent high throughputs in order to finish the separating process timely and

economically. Furthermore, the filtration system should be compatible with differences, resulting from batch to batch

component variability.

Recommendation

Prefiltration LPM, LPGF

Final filtration LPS, LPSD, LPSL

Prefiltration Sterile Filtration Sterile Holding Tank Final Filtration Bioreactor Fermentor

SterileVenting SterileVenting

Mix Tank

Media Powder

Facilities Water

Pharmaceutical grade water is defined as feed water common to process systems such as washers, autoclaves

or WFI systems. Since water source varies widely in quality, only appropriate filtration systems can ensure the

production to be effective, safe and successful.

Filtration is just one step of the manufacturing process of pharmaceutical grade water. Other steps may result in

the increasing of particles, for both resin and activated carbon beds could produce powder.

Separation Goals

● Prefiltration

Remove colloidal and particulate contaminants to extend the service life of final filters.

● Final Filtration

Remove particles, microorganisms and endotoxins to meet the requirements of FDA and other international standards.

● Prefilters must remove most particulate and colloidal contaminants effectively, and have high dirt-holding

capacity, and keep high flow rates and high throughputs.

● Final filters must remove microorganisms and endotoxins, and keep high flow rates and high throughputs.

LPNN for removing endotoxins

Filters with positive charge have limited capacity of removing endotoxins. Once the capacity is saturated, they lose this

ability of removing endotoxins. Series connection of two filters is the solution, monitoring the endotoxins between the two

filters. When endotoxins exist in the downstream of the first filter, the second filter should replace the first one in its position.

This can make full use of filters and ensure reliable retention rate. Replacement of filters with no charge depends on pre-

setting limitation index such as maximum differential pressure, minimum flow rate and maximum life time.

Recommendation

Prefiltration Sterile Filtration Final FiltrationCompression

Point of Use

Prefiltration Sterile Filtration Sterile Holding Tank Final Filtration

SterileVenting

Endotoxin

Removal

Point of Use

Large Volume Parenterals (LVPs) are single unit doses more than 50 cc. Prefiltration is used for removing particles to

extend the service life of final (sterilizing) filtration. Final filters are used for reducing bioburden or sterile filtration prior

to terminal sterilization. The volume of LVPs is usually tens of thousands of liters, and multiple filling lines may be working

at the same time.

Ingredients in typical LVP solutions include water, dextrose (from 5% to 50%), amino acid, salts and very viscous total

parenteral nutrition (TPN). Prefilters are used to reduce particles for salt solutions, and to remove hard particles for

dextrose solutions before final sterilizing filtration (it's another option to reduce bioburden by using 0.45 μm filters)

www.anowfilter.com9

● Prefiltration

Remove colloidal and particulate contaminants to extend the service life of downstream sterilizing filters

● Final filtration

Reduce bioburden prior to terminal sterilization (0.45 μm)

Sterile filtration prior to terminal sterilization (0.22 μm)

● LVP filters must provide consistent high flow rates to ensure the accuracy and consistency of filling.

● Since typical LVP filling process is operated under high differential pressure and high flow rates, filters must have superior

mechanical strength and be reliable and robust.

● The cost of LVP filters must be economical.

● Prefilters and sterilizing filters must bear multiple cycles of steam-in-place sterilization or hot water sanitization.

Prefiltration LPP, LPPF

Separation Goals

Recommendation

PrefiltrationSterile

Holding

Filtration

SterileVenting

Mix Tank

Powder

Filling Autoclave PackagingBioburden

Reduction

Small volume parenterals (SVP) include various traditional and bioengineered drugs. These drugs are usually packaged in

small vials (less than 20 ml), pre-filled syringes and ampoules, or made in lyophilized powder. Lots of SVPs need aseptic

processing for their lack of heat-stability.

Sterilizing filtration is used after synthesis or before filling. And it can add the sterility assurance if sterilizing filtration is used

at both locations. Prefilters should be used to reduce bioburden and particles, which would clog final filters prematurely.

● Prefiltration

Provide a sterile filtrate meeting the requirements of current regulatory

Separation Goals

● Final sterilizing filters should remove bacteria without altering the effects of drug products. Therefore, these filters

should have low adsorption of active pharmaceutical ingredient (API), low extractables, be non-pyrogenic and

integrity testable, and be sterile or can be sterilized.

● Prefilters and final filters should have enough flow rates. Final filters in the filling machine must have strong structures

to prevent media flexing during pulsed flow filling processing, which will result in particle release, drips or other

dispense problems.

Prefiltration LPP, LPM

Final filtration LPS, LPSD

Recommendation

PrefiltrationMix Tank

SterileVenting

Active

Pharmacetical

Ingredients

Filling Autoclave PackagingFinal Filtration

Formulation

Ingredients

Large Volume Parenterals (LVPs) are single unit doses more than 50 cc. Prefiltration is used for removing particles to

extend the service life of final (sterilizing) filtration. Final filters are used for reducing bioburden or sterile filtration prior

to terminal sterilization. The volume of LVPs is usually tens of thousands of liters, and multiple filling lines may be working

at the same time.

Ingredients in typical LVP solutions include water, dextrose (from 5% to 50%), amino acid, salts and very viscous total

parenteral nutrition (TPN). Prefilters are used to reduce particles for salt solutions, and to remove hard particles for

dextrose solutions before final sterilizing filtration (it's another option to reduce bioburden by using 0.45 μm filters)

www.anowfilter.com9

● Prefiltration

Reduce bioburden prior to terminal sterilization (0.45 μm)

Sterile filtration prior to terminal sterilization (0.22 μm)

● LVP filters must provide consistent high flow rates to ensure the accuracy and consistency of filling.

● Since typical LVP filling process is operated under high differential pressure and high flow rates, filters must have superior

mechanical strength and be reliable and robust.

● The cost of LVP filters must be economical.

● Prefilters and sterilizing filters must bear multiple cycles of steam-in-place sterilization or hot water sanitization.

Prefiltration LPP, LPPF

Separation Goals

Recommendation

Holding

Filtration

SterileVenting

Mix Tank

Powder

Filling Autoclave PackagingBioburden

Reduction

Small volume parenterals (SVP) include various traditional and bioengineered drugs. These drugs are usually packaged in

small vials (less than 20 ml), pre-filled syringes and ampoules, or made in lyophilized powder. Lots of SVPs need aseptic

processing for their lack of heat-stability.

Sterilizing filtration is used after synthesis or before filling. And it can add the sterility assurance if sterilizing filtration is used

at both locations. Prefilters should be used to reduce bioburden and particles, which would clog final filters prematurely.

● Prefiltration

Provide a sterile filtrate meeting the requirements of current regulatory

Separation Goals

● Final sterilizing filters should remove bacteria without altering the effects of drug products. Therefore, these filters

should have low adsorption of active pharmaceutical ingredient (API), low extractables, be non-pyrogenic and

integrity testable, and be sterile or can be sterilized.

● Prefilters and final filters should have enough flow rates. Final filters in the filling machine must have strong structures

to prevent media flexing during pulsed flow filling processing, which will result in particle release, drips or other

dispense problems.

Prefiltration LPP, LPM

Final filtration LPS, LPSD

Recommendation

PrefiltrationMix Tank

SterileVenting

Active

Pharmacetical

Ingredients

Filling Autoclave PackagingFinal Filtration

Formulation

Ingredients

Ophthalmic preparations, ranging from contact lens cleaning and storing solutions to washing solutions in eye surgery

and eye treatment products, must meet the rigid regulatory requirements and product specifications. The major

component of most ophthalmic solutions is water. Furthermore, there maybe salts such as NaCl, preventatives, vaseline for

the production of ointments and gel polymer used for lubricants. Heat-sensitive ophthalmic solutions can be sterilized by

sterilizing filtration or by adding sterilized components into pre-sterilized bulk solutions.

www.anowfilter.com

● Prefiltration

Reduce particles and bioburden prior to sterilizing filtration

Keep reliable retention of microorganisms for a long time

● Filters must provide consistent high flow rates and be robust to satisfy mass manufacturing processes.

● Sterilizing filters must keep reliable retention of microorganisms for a long time.

● Filters must have no adsorption or binding of preservatives in product manufacturing.

Final filtration LPS, LPSD, LPSHV

Separation Goals

Recommendation

Holding

Filtration

SterileVenting

Mix Tank

Ingredients

FillingSterile

Filtration

Human plasma contains lots of valuable therapeutic proteins, such as albumin, a variety of immunoglobulins, VⅢ

ófactors, fibrous proteins and other proteins. The process of extracting and purifying these proteins is called plasma

fractionation. Plasma fractionation is accomplished by a series of extracting and purifying such proteins.

Foreigners in plasma can result in instability of products and clogging of downstream filters. Therefore, prefilters are

necessary for classification and removing impurities prior to chromatography and ultrafiltration. Final filters are used for

the sterilizing filtration of heat-sensitive proteins.

● Prefiltration

Remove colloids, aggregates, non-targeted proteins, lipids and particles to protect sterilizing filters or chromatography

column prior to downstream purification.

Control the microorganism level during the manufacturing process.

Final sterile filling (referred to SVPs)

● Prefiltration must remove contaminants and have no retention of target products.

● Filters must have consistent high flow rates and high throughputs for the sake of time and cost.

● Filters should not contaminate feeding liquids, especially metals such as aluminum.

Prefiltration LPM, LPGF, LPPF

Separation Goals

Recommendation

ClarificationPrecipitation

Plasma

PrefiltrationVirus Inactivation

SterileVenting

Concentration Final Filtration

Ophthalmic preparations, ranging from contact lens cleaning and storing solutions to washing solutions in eye surgery

and eye treatment products, must meet the rigid regulatory requirements and product specifications. The major

component of most ophthalmic solutions is water. Furthermore, there maybe salts such as NaCl, preventatives, vaseline for

the production of ointments and gel polymer used for lubricants. Heat-sensitive ophthalmic solutions can be sterilized by

sterilizing filtration or by adding sterilized components into pre-sterilized bulk solutions.

www.anowfilter.com

● Prefiltration

Reduce particles and bioburden prior to sterilizing filtration

Keep reliable retention of microorganisms for a long time

● Filters must provide consistent high flow rates and be robust to satisfy mass manufacturing processes.

● Sterilizing filters must keep reliable retention of microorganisms for a long time.

● Filters must have no adsorption or binding of preservatives in product manufacturing.

Separation Goals

Recommendation

Holding

Filtration

SterileVenting

Mix Tank

Ingredients

FillingSterile

Filtration

Human plasma contains lots of valuable therapeutic proteins, such as albumin, a variety of immunoglobulins, VⅢ

ófactors, fibrous proteins and other proteins. The process of extracting and purifying these proteins is called plasma

fractionation. Plasma fractionation is accomplished by a series of extracting and purifying such proteins.

Foreigners in plasma can result in instability of products and clogging of downstream filters. Therefore, prefilters are

necessary for classification and removing impurities prior to chromatography and ultrafiltration. Final filters are used for

the sterilizing filtration of heat-sensitive proteins.

● Prefiltration

Remove colloids, aggregates, non-targeted proteins, lipids and particles to protect sterilizing filters or chromatography

column prior to downstream purification.

Control the microorganism level during the manufacturing process.

Final sterile filling (referred to SVPs)

● Prefiltration must remove contaminants and have no retention of target products.

● Filters must have consistent high flow rates and high throughputs for the sake of time and cost.

● Filters should not contaminate feeding liquids, especially metals such as aluminum.

Prefiltration LPM, LPGF, LPPF

Separation Goals

Recommendation

ClarificationPrecipitation

Plasma

PrefiltrationVirus Inactivation

SterileVenting

Concentration Final Filtration

LPSL filter cartridges are specially designed for sterilizing

filtration of plasma fractionation, lyophilized powder and

vaccines. They are featuring extremely low extractables

with no more than 10mg/10”, longer service life with 40

cycles of SIP. These filters can powerfully ensure final product

quality.

Application

● Plasma Fractionation

● Lyophilized Powder

● Vaccines

Specification

Support

Core, Cage and Drainage

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Maximum Differential Pressure

Integrity Test at 23 ℃

Membrane

Thermal Bonding, No Adhesives

Silicone/EPDM/Viton

PP (222/226 with encapsulated

stainless steel reinforcing ring)

Double Layer Hydrophilic PES

Diameter

Length5 inch, 10 inch, 20 inch, 30 inch

40 inch

≥ ( ) per 10-inch cartridge2 20.46m 4.9ft

0.45+0.22

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

Features and Benefits

● Double layer hydrophilic PES Membrane

● Low protein binding

● Extensive drug compatibility for critical applications

● Extremely low extractables

Quality

● Cartridges produced in a controlled

environment

● Manufactured according to ISO9001 certified

Quality Management System

www.anowfilter.com

Water bubble point≥ 3500 mbar (50 psig)

Air diffusion ≤ 30ml/min/10”@2.8bar

Low Extractable and Longer Service Life Filter Cartridge with

Double Layer PES Membrane

Bacterial Retention

Extractables

≤ 10 mg per autoclaved 10-inch cartridge after 24-h soak in purified water at controlled room temperature.

Effluent Particle Level

Meets the requirements of Chinese Pharmacopoeia

2010, Volume Ⅱ, appendix Ⅸ C.

Non-Fiber Releasing

Meets the criteria for a “non-fiber releasing” filter

as defined in 21 CFR 210.3 (b) (6).

Toxicity

Component materials meet GB/T 14233.2<2005> of

Chinese National Standard for Safety Tests.

Passed the bacterial challenge testing using Brevundimonas

diminuta(ATCC19146) at a minimum challenge concentration of 71 x 10 CFU/cm .

< 500 ppb after a water flush of 60 liters per 10-inch

cartridge.

Multiple Sterilization Cycles

40 steam-in-place sterilization or autoclave cycles of 30

min at 123 ℃.

Oxidizable Substances

Meets the criteria of Chinese Pharmacopoeia 2010,

volume Ⅱ for purified water.

Bacterial Endotoxins

< 0.25 EU/ml as determined by the LAL test.

Ordering Information

SL PES

【】Length【】Code

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

【】Code 【】Support

PP with stainless

steel endcapB

【】Code

Silicone

LP D42 C 1 0 BS

【】Seal

【】Code

D42 (0.45+

0.22)μm

【】Rating【】Code

End CapConfiguration【】 Media

【【

Typical Liquid Flow Rate@23 ℃

Water Flow Rate(L/min/10")

al Pre

(mbar)

(0.22+0.45)μm

20 30 40 50

PP with stainless

steel liningC

Maximum Operating Temperature

A: PP <60 ℃ (140℉)

B: PP with stainless steel lined end cap <85℃ (185℉)

C: PP with stainless steel lining <95℃ (203℉)

LPSL filter cartridges are specially designed for sterilizing

filtration of plasma fractionation, lyophilized powder and

vaccines. They are featuring extremely low extractables

with no more than 10mg/10”, longer service life with 40

cycles of SIP. These filters can powerfully ensure final product

quality.

Application

● Vaccines

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

Silicone/EPDM/Viton

Diameter

Length5 inch, 10 inch, 20 inch, 30 inch

40 inch

≥ ( ) per 10-inch cartridge2 20.46m 4.9ft

0.45+0.22

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

● Double layer hydrophilic PES Membrane

● Extensive drug compatibility for critical applications

● Extremely low extractables

Quality

environment

www.anowfilter.com

Water bubble point≥ 3500 mbar (50 psig)

Air diffusion ≤ 30ml/min/10”@2.8bar

Low Extractable and Longer Service Life Filter Cartridge with

Double Layer PES Membrane

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

diminuta(ATCC19146) at a minimum challenge concentration of 71 x 10 CFU/cm .

cartridge.

min at 123 ℃.

SL PES

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

【】Code 【】Support

PP with stainless

steel endcapB

【】Code

Silicone

LP D42 C 1 0 BS

【】Seal

【】Code

D42 (0.45+

0.22)μm

【【

al Pre

(mbar)

(0.22+0.45)μm

20 30 40 50

PP with stainless

steel liningC

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPSHT Highly Asymmetric PES Filter Cartridge for Higher Throughput Demands

LPSHT filter cartridges are integrity testable membrane

filters, specially developed for terminal filtration needing high

throughputs, such as cell culture media, large volume

parenterals and vaccines applications. They are

characterized by a unique highly asymmetric, hydrophilic

polyethersulfone membrane, offering higher throughputs,

low protein adsorption and superior microbiological safety.

Application

● Cell Culture Medium

● Large Volume Parenterals

● Vaccines

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Integrity Test-Water Bubble Point

at 23 ℃

Membrane

Silicone/EPDM/Viton

Highly Asymmetric Hydrophilic PES

Diameter

Length5 inch, 10 inch, 20 inch,

30 inch, 40 inch

2≥ (5.7ft ) per 10-inch cartridge20.53m

0.1, 0.22, 0.45, 0.65, 0.8, 1.2, 3.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.1 μm≥ 3800 mbar (55 psig)

0.22 μm≥ 3400 mbar (49 psig)

0.45 μm≥ 2300 mbar (33 psig)

● Highly asymmetric, hydrophilic polyethersulfone

membrane

● Absolute bacteria retention

● Long service life and high flow rates

Quality

environment

SHT PES

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

【】Code 【】Support【】Code

Silicone

LP 022 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

0.65μm

0.8μm

1.2μm

3.0μm

【【

Bacterial Retention

(for 0.1 μm & 0.22 μm only)

Extractables

Non-Fiber Releasing

Toxicity

diminuta(ATCC19146) at a minimum challenge concentration of 7 21 x 10 CFU/cm .

cartridge.

min at 123 ℃.

al Pre

(mbar) 0.1

20 30 40 50

0.22μm

0.45μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPSHT Highly Asymmetric PES Filter Cartridge for Higher Throughput Demands

LPSHT filter cartridges are integrity testable membrane

filters, specially developed for terminal filtration needing high

throughputs, such as cell culture media, large volume

parenterals and vaccines applications. They are

characterized by a unique highly asymmetric, hydrophilic

polyethersulfone membrane, offering higher throughputs,

low protein adsorption and superior microbiological safety.

Application

● Large Volume Parenterals

● Vaccines

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Highly Asymmetric Hydrophilic PES

Diameter

30 inch, 40 inch

2≥ (5.7ft ) per 10-inch cartridge20.53m

0.1, 0.22, 0.45, 0.65, 0.8, 1.2, 3.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.1 μm≥ 3800 mbar (55 psig)

0.22 μm≥ 3400 mbar (49 psig)

0.45 μm≥ 2300 mbar (33 psig)

● Highly asymmetric, hydrophilic polyethersulfone

membrane

Quality

environment

SHT PES

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

0.65μm

0.8μm

1.2μm

3.0μm

【【

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

diminuta(ATCC19146) at a minimum challenge concentration of 7 21 x 10 CFU/cm .

cartridge.

min at 123 ℃.

al Pre

(mbar) 0.1

20 30 40 50

0.22μm

0.45μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPSHV PES Filter Cartridge for Sterile Filtration of High Viscous Pharmacy

LPSHV filter cartridges are designed for terminal filtration,

specially for high viscosity liquids in biopharmaceutical industry,

such as ophthalmic solutions, parenterals and vaccines.

Because of high dirt holding capacity and low protein

adsorption performance, these filters have longer service

life for high viscosity pharmacy filtration.

Application

● Ophthalmic Solution

● Parenterals with High Viscosity(Large Volume

Parenterals, Small Volume Parenterals)

● Vaccines

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Hydrophilic PES

Diameter

30 inch, 40 inch

≥ per 10-inch cartridge2 20.53m (5.7ft )

0.1, 0.22, 0.45, 0.65, 0.8, 1.2, 3.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.1 μm≥ 3800 mbar (55 psig)

0.22 μm≥ 3400 mbar (49 psig)

0.45 μm≥ 2300 mbar (33 psig)

Quality

environment

SHV PES

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

0.65μm

0.8μm

1.2μm

3.0μm

【【

lPP with stainless

steel endcapB

PP with stainless

steel liningC

600cp Fluid Flow Rate(L/min/10")

al Pre

(mbar) 0.

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

diminuta(ATCC19146) at a minimum challenge concentration of 71 x 10 CFU/ .2cm

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPSHV PES Filter Cartridge for Sterile Filtration of High Viscous Pharmacy

LPSHV filter cartridges are designed for terminal filtration,

specially for high viscosity liquids in biopharmaceutical industry,

such as ophthalmic solutions, parenterals and vaccines.

Because of high dirt holding capacity and low protein

adsorption performance, these filters have longer service

life for high viscosity pharmacy filtration.

Application

● Parenterals with High Viscosity(Large Volume

Parenterals, Small Volume Parenterals)

● Vaccines

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Hydrophilic PES

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 0.8, 1.2, 3.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.1 μm≥ 3800 mbar (55 psig)

0.22 μm≥ 3400 mbar (49 psig)

0.45 μm≥ 2300 mbar (33 psig)

Quality

environment

SHV PES

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

0.65μm

0.8μm

1.2μm

3.0μm

【【

lPP with stainless

steel endcapB

PP with stainless

steel liningC

600cp Fluid Flow Rate(L/min/10")

al Pre

(mbar) 0.

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPS Single Layer Hydrophilic PES Filter Cartridge for Final Filtration of Pharmacy

LPS filter cartridges are integrity testable membrane filters

specially developed for sterilizing filtration in

biopharmaceutical industry. They are characterized by a

unique asymmetric, hydrophilic polyethersulfone membrane,

offering high throughputs, low protein adsorption and superior

microbiological safety.

Application

● Active Pharmaceutical Ingredient

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Single Layer Hydrophilic PES

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 0.8, 1.2, 3.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85℃ ℃

0.1 μm≥ 3800 mbar (55 psig)

0.22 μm≥ 3400 mbar (49 psig)

0.45 μm≥ 2300 mbar (33 psig)

Quality

environment

● Parenterals(Large Volume Parenterals, Small

Volume Parenterals)

● Vaccines

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

0.65μm

0.8μm

1.2μm

3.0μm

【【

lPP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar) 0.2

20 30 40 50

0.45μm

0.65μm

1.2μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPS Single Layer Hydrophilic PES Filter Cartridge for Final Filtration of Pharmacy

LPS filter cartridges are integrity testable membrane filters

specially developed for sterilizing filtration in

biopharmaceutical industry. They are characterized by a

unique asymmetric, hydrophilic polyethersulfone membrane,

offering high throughputs, low protein adsorption and superior

microbiological safety.

Application

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Single Layer Hydrophilic PES

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 0.8, 1.2, 3.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85℃ ℃

0.1 μm≥ 3800 mbar (55 psig)

0.22 μm≥ 3400 mbar (49 psig)

0.45 μm≥ 2300 mbar (33 psig)

Quality

environment

Volume Parenterals)

● Vaccines

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

0.65μm

0.8μm

1.2μm

3.0μm

【【

lPP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar) 0.2

20 30 40 50

0.45μm

0.65μm

1.2μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPSD filter cartridges are characterized by a unique highly

asymmetric, double-layer hydrophilic polyethersulfone

membrane, specially designed for extremely demanding of

sterilizing filtration in biopharmaceutical industry. These filters

can powerfully ensure products meeting the rigid

requirements of current regulatory.

Application

Volume Parenterals)

● Vaccines

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Diameter

Length5 inch, 10 inch, 20 inch, 30 inch,

40inch

≥ 0.44 per 10-inch cartridge2 2m (4.8ft )

0.22+0.1, 0.22+0.22, 0.45+0.22

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.22 μm + 0.1 μm≥ 4000 mbar (58 psig)

0.22 μm + 0.22 μm≥ 3700 mbar (53 psig)

0.45 μm + 0.22 μm≥3500 mbar (50 psig)

● Double layer hydrophilic PES membrane

● Low protein binding and extensive drug

compatibility for critical applications

● Integrity testable

Quality

environment

Double Layer Hydrophilic PES Filter Cartridge for

Extremely Demanding of Sterilizing Filtration

30 30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP D22 C 1 0 BS

【】Seal

【】Code

0.22+0.1μm

0.22+0.22μm

0.45+0.22μm

【【

lPP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

(0.45+0.22)μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

40 40inch

www.anowfilter.com

LPSD filter cartridges are characterized by a unique highly

asymmetric, double-layer hydrophilic polyethersulfone

membrane, specially designed for extremely demanding of

sterilizing filtration in biopharmaceutical industry. These filters

can powerfully ensure products meeting the rigid

requirements of current regulatory.

Application

Volume Parenterals)

● Vaccines

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Diameter

Length5 inch, 10 inch, 20 inch, 30 inch,

40inch

0.22+0.1, 0.22+0.22, 0.45+0.22

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.22 μm + 0.1 μm≥ 4000 mbar (58 psig)

0.22 μm + 0.22 μm≥ 3700 mbar (53 psig)

0.45 μm + 0.22 μm≥3500 mbar (50 psig)

● Double layer hydrophilic PES membrane

● Low protein binding and extensive drug

compatibility for critical applications

● Integrity testable

Quality

environment

Double Layer Hydrophilic PES Filter Cartridge for

Extremely Demanding of Sterilizing Filtration

30 30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP D22 C 1 0 BS

【】Seal

【】Code

0.22+0.1μm

0.22+0.22μm

0.45+0.22μm

【【

lPP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

(0.45+0.22)μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

40 40inch

www.anowfilter.com

LPT Hydrophobic PTFE Filter Cartridge with Broad Chemical Compatibility

LPT filter cartridges are characterized by permanently

hydrophobic PTFE membrane, specially developed for

sterile filtration of Active Pharmaceutical Ingredients

production. They are integrity testable, providing high

throughputs, broad chemical compatibility and high flow

rates. Due to their hydrophobic characteristic, they must

be pre-wetted with ethanol or IPA before the filtration of

aqueous solutions.

● Broad chemical compatibility

● High throughputs and superior flow rates

● 100% integrity testable prior to release

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Integrity Test-60/40% IPA/Water

Bubble Point at 23 ℃

Membrane

EPDM/Viton/Silicone

Hydrophobic PTFE

Diameter

30 inch, 40 inch

0.05 0.1, 0.22, 0.45, 1.0,3.0, , 5.0, 10

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85 ℃

0.1 μm≥ 1000 mbar (14.5 psig)

0.22 μm≥ 900 mbar (13 psig)

0.45 μm≥ 300 mbar (4.35 psig)

Application

● Organic solvent filtration

● Filtration for harsh chemicals and HPLC mobile

phases that destroy other membrane materials

● Sterile filtration for aqueous media

Filtration for strongly corrosive or oxidizing solutions●

T HydrophobicPTFE

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

【【

Notes: They must be pre-wetted with ethanol or IPA before the filtration of aqueous solutions.

005 0.05μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPT Hydrophobic PTFE Filter Cartridge with Broad Chemical Compatibility

LPT filter cartridges are characterized by permanently

hydrophobic PTFE membrane, specially developed for

sterile filtration of Active Pharmaceutical Ingredients

production. They are integrity testable, providing high

throughputs, broad chemical compatibility and high flow

rates. Due to their hydrophobic characteristic, they must

be pre-wetted with ethanol or IPA before the filtration of

aqueous solutions.

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

EPDM/Viton/Silicone

Hydrophobic PTFE

Diameter

30 inch, 40 inch

0.05 0.1, 0.22, 0.45, 1.0,3.0, , 5.0, 10

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85 ℃

0.1 μm≥ 1000 mbar (14.5 psig)

0.22 μm≥ 900 mbar (13 psig)

0.45 μm≥ 300 mbar (4.35 psig)

Application

● Filtration for harsh chemicals and HPLC mobile

phases that destroy other membrane materials

T HydrophobicPTFE

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

【【

Notes: They must be pre-wetted with ethanol or IPA before the filtration of aqueous solutions.

005 0.05μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPTA filter cartridges are featured by permanently hydrophobic

PTFE membrane, specially designed for sterile venting and gas

application in biopharmaceutical industry. They are integrity

testable, offering the highest process security, high throughputs,

extreme humidity and stringent in-line steam sterilizations

● High flow rates and low pressure drop

● High strength, long service life and cost-effective

● Have a particulate removal rating of 0.01 m in gases

and a microbial removal rating of 0.22 μm in liquids

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Removal Rating, μm

Membrane

Silicone/EPDM/Viton

Double-layer Polytetrafluoroethylene

(PTFE)

Diameter

30 inch, 40 inch

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85 ℃

Bubble point≥ 1100 mbar with 60/40% IPA/water(15.95 psig)

HydroCorr (water intrusion test)≤ 0.75mL/min per 10-inch cartridge

with water at 2620mbar

LPTA Hydrophobic PTFE Filter Cartridge for Sterilizing Filtration of Air/Gas

Application

● Sterile venting of vessels and carboys

● Autoclave vacuum break lines

● Fermentation air applications

● Sterile process gases

● Bioreactor inlet and outlet gas filtration

● Sterile filtration of CO2

TA HydrophobicPTFE for air

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 001 C 1 0

【】Code 【】Rating【】Code

【【

Extractables

cartridge.

min at 123 ℃.

001 0.01μm

Silicone

【】Seal

Bacterial Retention

Toxicity

Non-Fiber Releasing

PP with stainless

steel endcapB

PP with stainless

steel liningC

3Nitrogen Flow Rate(m /h/10")

al Pre

(mbar)

0 bar outlet pressure

60 90 120 150

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPTA filter cartridges are featured by permanently hydrophobic

PTFE membrane, specially designed for sterile venting and gas

application in biopharmaceutical industry. They are integrity

testable, offering the highest process security, high throughputs,

extreme humidity and stringent in-line steam sterilizations

● High flow rates and low pressure drop

● High strength, long service life and cost-effective

● Have a particulate removal rating of 0.01 m in gases

and a microbial removal rating of 0.22 μm in liquids

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Removal Rating, μm

Membrane

Silicone/EPDM/Viton

Double-layer Polytetrafluoroethylene

(PTFE)

Diameter

30 inch, 40 inch

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85 ℃

Bubble point≥ 1100 mbar with 60/40% IPA/water(15.95 psig)

HydroCorr (water intrusion test)≤ 0.75mL/min per 10-inch cartridge

with water at 2620mbar

LPTA Hydrophobic PTFE Filter Cartridge for Sterilizing Filtration of Air/Gas

Application

● Sterile venting of vessels and carboys

● Autoclave vacuum break lines

● Fermentation air applications

● Sterile process gases

● Bioreactor inlet and outlet gas filtration

● Sterile filtration of CO2

TA HydrophobicPTFE for air

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 001 C 1 0

【【

Extractables

cartridge.

min at 123 ℃.

001 0.01μm

Silicone

【】Seal

Bacterial Retention

Toxicity

Non-Fiber Releasing

PP with stainless

steel endcapB

PP with stainless

steel liningC

3Nitrogen Flow Rate(m /h/10")

al Pre

(mbar)

60 90 120 150

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPNN Hydrophilic Nylon Filter Cartridge for Sterile Filtration of Facilities Water & API

LPNN filter cartridges are characterized by hydrophilic

Nylon membrane, providing high throughputs, low

extractables and good mechanical strength, widely used

for sterile filtration in Active Pharmaceutical Ingredients

production and facilities water, for removing particles,

microorganisms and endotoxins to meet the requirements

of FDA and other international standards.

● Low extractables and high absorption

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Hydrophilic Nylon

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.22 μm≥ 2800 mbar (40.6 psig)

0.45 μm≥ 1200 mbar (17.4 psig)

● Facilities water

● Active pharmaceutical ingredients

Application

NN Nylon

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

【【

065 0.65μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

1.0μm3.0μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPNN Hydrophilic Nylon Filter Cartridge for Sterile Filtration of Facilities Water & API

LPNN filter cartridges are characterized by hydrophilic

Nylon membrane, providing high throughputs, low

extractables and good mechanical strength, widely used

for sterile filtration in Active Pharmaceutical Ingredients

production and facilities water, for removing particles,

microorganisms and endotoxins to meet the requirements

of FDA and other international standards.

● Low extractables and high absorption

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

at 23 ℃

Membrane

Silicone/EPDM/Viton

Hydrophilic Nylon

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

0.22 μm≥ 2800 mbar (40.6 psig)

0.45 μm≥ 1200 mbar (17.4 psig)

● Facilities water

● Active pharmaceutical ingredients

Application

NN Nylon

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

【【

065 0.65μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

1.0μm3.0μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPTL Hydrophilic PTFE Filter Cartridge for Solvent Filtration

LPTL filter cartridges are characterized by hydrophilic PTFE

membrane and polypropylene components for broad

applications, widely used in Active Pharmaceutical Ingredients

production in a variety of solvent filtration.

● No need of pre-wetting

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

Viton/EPDM/Silicone

Hydrophilic Polytetrafluoroethylene

(PTFE)

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 1.0

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

0.1 μm≥1100 mbar (16 psig)

0.22 μm≥ 900 mbar (13 psig)

Application

● Filtration for harsh chemicals

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

【【

TL HydrophilicPTFE

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com

LPTL Hydrophilic PTFE Filter Cartridge for Solvent Filtration

LPTL filter cartridges are characterized by hydrophilic PTFE

membrane and polypropylene components for broad

applications, widely used in Active Pharmaceutical Ingredients

production in a variety of solvent filtration.

● No need of pre-wetting

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

Viton/EPDM/Silicone

Hydrophilic Polytetrafluoroethylene

(PTFE)

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 1.0

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

0.1 μm≥1100 mbar (16 psig)

0.22 μm≥ 900 mbar (13 psig)

Application

● Filtration for harsh chemicals

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 022 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

【【

TL HydrophilicPTFE

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

www.anowfilter.com31

LPM Hydrophilic MCE Filter Cartridge for Prefiltration of Biologicals

LPM filter cartridges are characterized by high-

performance, hydrophilic mixed cellulose esters

membrane, offering high flow rates, low protein

adsorption and superior microbiological safety.

These filters are designed to reduce costs and are

especially suited for prefiltration of vaccines and

plasma fractionation production.

● Superior throughputs and cost-effective

● High retention efficiency for more critical

degrees of prefiltration

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

Silicone/EPDM/Viton

Hydrophilic MCE

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

Application

● Vaccines

Integrity Test-Water Bubble Point at 23 ℃

0.22μm≥1000 mbar (14.5 psig)

0.45 μm≥ 500 mbar (7.25 psig)

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 045 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

【【

065 0.65μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

LPM Hydrophilic MCE Filter Cartridge for Prefiltration of Biologicals

LPM filter cartridges are characterized by high-

performance, hydrophilic mixed cellulose esters

membrane, offering high flow rates, low protein

adsorption and superior microbiological safety.

These filters are designed to reduce costs and are

especially suited for prefiltration of vaccines and

plasma fractionation production.

● Superior throughputs and cost-effective

● High retention efficiency for more critical

degrees of prefiltration

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

Silicone/EPDM/Viton

Hydrophilic MCE

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

Application

● Vaccines

Integrity Test-Water Bubble Point at 23 ℃

0.22μm≥1000 mbar (14.5 psig)

0.45 μm≥ 500 mbar (7.25 psig)

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 045 C 1 0 BS

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

【【

065 0.65μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

LPV Hydrophobic PVDF Filter Cartridge with Low Protein Binding

LPV filter cartridges are characterized by hydrophobic PVDF

membrane and polypropylene components, featuring lowest

protein binding. Due to these characterizes, they are ideal for

sterile filtration of biologicals, chemical intermediates and

organic solvents.

● Minimum protein binding and low extractables

● Superior throughputs and high flow rates

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

Silicone/Viton/EPDM

Hydrophobic PVDF

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

0.1 μm≥ 400 mbar (5.8 psig)

0.22 μm≥ 300 mbar (4.35 psig)

Application

● Biologicals

● Chemical intermediates

● Organic solvents

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 045 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

【【

V HydrophobicPVDF

PP with stainless

steel endcapB

PP with stainless

steel liningC

300 3.0μm

500 5.0μm

065 0.65μm

al Pre

(mbar) 0.1μm

4 6 8 10

0.22μm0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

LPV Hydrophobic PVDF Filter Cartridge with Low Protein Binding

LPV filter cartridges are characterized by hydrophobic PVDF

membrane and polypropylene components, featuring lowest

protein binding. Due to these characterizes, they are ideal for

sterile filtration of biologicals, chemical intermediates and

organic solvents.

● Minimum protein binding and low extractables

● Superior throughputs and high flow rates

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Membrane

Silicone/Viton/EPDM

Hydrophobic PVDF

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

0.1 μm≥ 400 mbar (5.8 psig)

0.22 μm≥ 300 mbar (4.35 psig)

Application

● Biologicals

● Chemical intermediates

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

Silicone

LP 045 C 1 0 BE

【】Seal

【】Code

0.1μm

0.22μm

0.45μm

1.0μm

【【

V HydrophobicPVDF

PP with stainless

steel endcapB

PP with stainless

steel liningC

300 3.0μm

500 5.0μm

065 0.65μm

al Pre

(mbar) 0.1μm

4 6 8 10

0.22μm0.45μm

Bacterial Retention

Extractables

Non-Fiber Releasing

Toxicity

cartridge.

min at 123 ℃.

A: PP <60 ℃ (140℉)

LPP filter cartridges are constructed of polypropylene fine fiber,

featuring high flow rates and high dirt holding capacity. They

are the most economical and efficient prefilters in

biopharmaceutical industry, removing most particulate and

colloidal contaminants. These filters can be personalized

according to your specific fluids and processes, such as pore

size and other characteristics, improving filtration efficiency and

reducing filtration costs.

● Superior dirt-holding capacity

● High flow rates

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0, 10, 20

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

LPP The Most Economical PP Filter Cartridge for Prefiltration

Application

Volume Parenterals)

● Vaccines

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 100 C 1 0

【【

Extractables

cartridge.

Sterilization

Support steam-in-place sterilization or autoclave at 123℃.

Meets the criteria of Chinese Pharmacopoeia 2010, volume Ⅱ

for purified water.

Silicone

【】Seal

Particle Removal Efficiency (%)

Toxicity

≥ 80

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

065 0.65μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

3.0μm

20 30 40 50

0.22μm0.45μm

1.0μm

A: PP <60 ℃ (140℉)

LPP filter cartridges are constructed of polypropylene fine fiber,

featuring high flow rates and high dirt holding capacity. They

are the most economical and efficient prefilters in

biopharmaceutical industry, removing most particulate and

colloidal contaminants. These filters can be personalized

according to your specific fluids and processes, such as pore

size and other characteristics, improving filtration efficiency and

● High flow rates

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Diameter

30 inch, 40 inch

0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0, 10, 20

Forward: 4.2 bar @ 23℃; 1.5 bar @ 85℃

LPP The Most Economical PP Filter Cartridge for Prefiltration

Application

Volume Parenterals)

● Vaccines

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 100 C 1 0

【【

Extractables

cartridge.

Sterilization

for purified water.

Silicone

【】Seal

Toxicity

≥ 80

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

5.0μm

065 0.65μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

3.0μm

20 30 40 50

0.22μm0.45μm

1.0μm

A: PP <60 ℃ (140℉)

LPPF filter cartridges are constructed of multilayer

polypropylene, featuring high flow rates, broad

chemical compatibility and high dirt holding capacity.

These filters are ideal for prefiltration in

biopharmaceutical industry, removing particulate and

colloidal contaminants. And these cartridges can be

personalized according to your specific filtration fluids

and processes, improving filtration efficiency and

● Reliable retention of particulates

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Multi-layer PP

Diameter

30 inch, 40 inch

2 20.2~0.3 m (2.1~3.2 ft ) per 10-inch element

0.5, 1.0, 3.0, 5.0, 10, 20

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85 ℃

LPPF The Most Efficient multi-layer PP Filter Cartridge for Prefiltration

Application

● Active Pharmaceutical Ingredients

Volume Parenterals)

● Vaccines

PF Multi-layer PP

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 100 C 1 0

【【

Extractables

cartridge.

Sterilization

for purified water.

Silicone

【】Seal

Toxicity

≥ 90

1.0μm

3.0μm

5.0μm

050 0.5μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

1.0μm

3.0μm

5.0μm

A: PP <60 ℃ (140℉)

LPPF filter cartridges are constructed of multilayer

polypropylene, featuring high flow rates, broad

chemical compatibility and high dirt holding capacity.

These filters are ideal for prefiltration in

biopharmaceutical industry, removing particulate and

colloidal contaminants. And these cartridges can be

personalized according to your specific filtration fluids

and processes, improving filtration efficiency and

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Multi-layer PP

Diameter

30 inch, 40 inch

0.5, 1.0, 3.0, 5.0, 10, 20

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85 ℃

LPPF The Most Efficient multi-layer PP Filter Cartridge for Prefiltration

Application

● Active Pharmaceutical Ingredients

Volume Parenterals)

● Vaccines

PF Multi-layer PP

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 100 C 1 0

【【

Extractables

cartridge.

Sterilization

for purified water.

Silicone

【】Seal

Toxicity

≥ 90

1.0μm

3.0μm

5.0μm

050 0.5μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

1.0μm

3.0μm

5.0μm

A: PP <60 ℃ (140℉)

LPAP absolute filter cartridges are constructed of

polypropylene fine fiber, featuring high flow rates, high

dirt holding capacity and reliable particle removal

efficiency. Due to their features, they are the most

economical and efficient prefilter cartridges, ideal for

the wide range of classification and prefiltration in

Biopharmaceutical Industry, especially in Active

Pharmaceutical Ingredients Manufacturing.

● Low extractables and low protein binding

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Absolute PP

Diameter

30 inch, 40 inch

0.5, 1.0, 3.0, 5.0, 10, 20

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85℃

LPAP Absolute PP Filter Cartridge for Active Pharmaceutical Ingredients

Application

parenterals, organic solvents, DIW

● Clarification

● Prefiltration for air & gas

Prefiltration for chemical intermediates, biologicals,

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 100 C 1 0

【【

Silicone

【】Seal

1.0μm

3.0μm

5.0μm

050 0.5μm

Extractables

cartridge.

Sterilization

for purified water.

Toxicity

≥ 95

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

1.0μm

3.0μm

A: PP <60 ℃ (140℉)

LPAP absolute filter cartridges are constructed of

polypropylene fine fiber, featuring high flow rates, high

dirt holding capacity and reliable particle removal

efficiency. Due to their features, they are the most

economical and efficient prefilter cartridges, ideal for

the wide range of classification and prefiltration in

Biopharmaceutical Industry, especially in Active

Pharmaceutical Ingredients Manufacturing.

● Low extractables and low protein binding

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Absolute PP

Diameter

30 inch, 40 inch

0.5, 1.0, 3.0, 5.0, 10, 20

Forward: 4.2 bar @ 23 ℃; 1.5 bar @ 85℃

LPAP Absolute PP Filter Cartridge for Active Pharmaceutical Ingredients

Application

parenterals, organic solvents, DIW

● Clarification

● Prefiltration for air & gas

Prefiltration for chemical intermediates, biologicals,

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 100 C 1 0

【【

Silicone

【】Seal

1.0μm

3.0μm

5.0μm

050 0.5μm

Extractables

cartridge.

Sterilization

for purified water.

Toxicity

≥ 95

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

20 30 40 50

1.0μm

3.0μm

A: PP <60 ℃ (140℉)

LFGF filter cartridges are adsorption depth filters,

designed for removing colloidal and viscous

contaminants in vaccines and culture media. Featured

by high dirt holding capacity and excellent particle

retention ability, these filters can effectively protect the

final cartridges to extend the service life.

● High throughputs and high adsorption

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Glass Fiber

Diameter

30 inch, 40 inch

≥ 0.37 per 10-inch element2 2m (4.0ft )

0.45, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

Application

● Vaccines

● Culture Media

● Colloidal and viscous liquids

LPGF Glass Fiber Filter Cartridge for Prefiltration of Viscous Pharmacy and Vaccines

GF Glass Fiber

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 045 C 1 0

【【

Extractables

cartridge.

Sterilization

for purified water.

Silicone

【】Seal

Toxicity

≥ 95

1.0μm

3.0μm

5.0μm

045 0.45μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

0.45μm

20 30 40 50

1.0μm

A: PP <60 ℃ (140℉)

LFGF filter cartridges are adsorption depth filters,

designed for removing colloidal and viscous

contaminants in vaccines and culture media. Featured

by high dirt holding capacity and excellent particle

retention ability, these filters can effectively protect the

final cartridges to extend the service life.

● High throughputs and high adsorption

Quality

environment

Specification

Support

End Caps

O-rings/Gasket

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Filter Media

Silicone/EPDM/Viton

Glass Fiber

Diameter

30 inch, 40 inch

≥ 0.37 per 10-inch element2 2m (4.0ft )

0.45, 1.0, 3.0, 5.0

Forward: 4.2 bar @ 23 ; 1.5 bar @ 85 ℃ ℃

Application

● Vaccines

● Culture Media

● Colloidal and viscous liquids

LPGF Glass Fiber Filter Cartridge for Prefiltration of Viscous Pharmacy and Vaccines

GF Glass Fiber

40 40inch

30inch

20inch

10inch

222/Fin

222/Flat

226/Fin

226/Flat

【】Code

LP 045 C 1 0

【【

Extractables

cartridge.

Sterilization

for purified water.

Silicone

【】Seal

Toxicity

≥ 95

1.0μm

3.0μm

5.0μm

045 0.45μm

PP with stainless

steel endcapB

PP with stainless

steel liningC

al Pre

(mbar)

0.45μm

20 30 40 50

1.0μm

A: PP <60 ℃ (140℉)

CTP Tri-Clamp capsule filters are designed to provide

smart, disposable and safe filtration for small capacity

liquids of lyophilized powder and other pharmacy. These

disposable filters can help eliminate cleaning problems

and extra validation costs. The T-style configuration is

ideal for operation. 100% integrity testable prior to release

ensures high quality products.

● Eco-friendly and cost-effective

● Smart, disposable and safe

● Low hold-up volume

● Good resistance to pressure

Quality

environment

Specification

Support & Housing

Sealing Technology

Filtration Area

Pore Size, μm

Maximum Forward Differential Pressure

Filter Media

PES/Nylon/PTFE/PP/GF/PVDF/MCE

≥ 0.2 2 2m (2.2ft )

Please refer to Ordering Information.

Liquid: 3.5 bar @ 23℃ and 3.0 bar @ 60℃

CTP Tri-Clamp Capsule Filter for Small Volume & High Value-added Pharmacy

Air&Gas: 3.0 bar @ 23℃ and 2.5 bar @ 60℃

Bacterial Retention (for 0.01 μm, 0.1 μm,

0.22 μm PES/PTFE )

diminuta(ATCC19146) at a minimum challenge concentration 7 2of 1 x 10 CFU/cm .

Sterilization

3 autoclave cycles of 30 min at 123 ℃; steam-in-place

sterilization not recommended.

For more information on specification, please refer to cartridges

with the same membrane.

【】Code

CTP 010 FS 5

Connection【】 Media

【【

0.1μm

0.22μm

001 0.01(for air)

NN Nylon

TL HydrophilicPTFE

TA HydrophobicPTFE for Air

T HydrophobicPTFE

GF Glass Fiber

VHydrophobic

100 1.0μm

045 0.45μm

300 3.0μm

∅82.5

Inlet/Outlet: Tri-clampVent&Drain: Silicone

Inlet/Outlet: Tri-clampVent&Drain: EPDM

500 5.0μm

Typical Liquid Flow Rate @23 ℃

0 0.4 0.8 1.2 1.6 2.0

al Pre

(mbar)

Water Flow Rate(L/min)

0 0.5 1.0 1.5 2.0 2.5

al Pre

(mbar)

PP PTFE

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

CTP Tri-Clamp capsule filters are designed to provide

smart, disposable and safe filtration for small capacity

liquids of lyophilized powder and other pharmacy. These

disposable filters can help eliminate cleaning problems

and extra validation costs. The T-style configuration is

ideal for operation. 100% integrity testable prior to release

Quality

environment

Specification

Support & Housing

Sealing Technology

Filtration Area

Pore Size, μm

Filter Media

PES/Nylon/PTFE/PP/GF/PVDF/MCE

≥ 0.2 2 2m (2.2ft )

CTP Tri-Clamp Capsule Filter for Small Volume & High Value-added Pharmacy

0.22 μm PES/PTFE )

diminuta(ATCC19146) at a minimum challenge concentration 7 2of 1 x 10 CFU/cm .

Sterilization

3 autoclave cycles of 30 min at 123 ℃; steam-in-place

sterilization not recommended.

【】Code

CTP 010 FS 5

【【

0.1μm

0.22μm

001 0.01(for air)

NN Nylon

TL HydrophilicPTFE

T HydrophobicPTFE

GF Glass Fiber

VHydrophobic

100 1.0μm

045 0.45μm

300 3.0μm

∅82.5

Inlet/Outlet: Tri-clampVent&Drain: Silicone

Inlet/Outlet: Tri-clampVent&Drain: EPDM

500 5.0μm

0 0.4 0.8 1.2 1.6 2.0

al Pre

(mbar)

0 0.5 1.0 1.5 2.0 2.5

al Pre

(mbar)

PP PTFE

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

CHP Hose Barb capsule filters are designed to provide

smart, disposable and safe filtration for small volume

liquid and high value-added liquid of lyophilized

powder and other pharmacy. Disposable filters can

help eliminate cleaning problems and extra validation

costs. 100% integrity testable prior to release ensures

high quality products.

Quality

environment

Specification

Support & Housing

Sealing Technology

Filtration Area

Pore Size, μm

Filter Media

PES/Nylon/PTFE/PP/MCE/

PVDF/GF

≥ 0.2 2 2m (2.2ft )

CHP Hose Barb Capsule Filter for Small Volume & High Value-added Pharmacy

0.22 μm PES/PTFE )

diminuta(ATCC19146) at a minimum challenge concentration7 2 of 1 x 10 CFU/cm .

Sterilization

3 autoclave cycles of 30 min at 123 ℃; steam-in-place sterilization

not recommended.

【】Code

CHP 022 DS 5

【【

0.1μm

0.22μm

001 0.01(for air)

NN Nylon

TL HydrophilicPTFE

T HydrophobicPTFE

GF Glass Fiber

V HydrophobicPVDF

100 1.0μm

045 0.45μm

Hose barb 13.6mm

∅7.5

Inlet/Outlet: 13.6mmVent/Drain: 7.5mmWith Silicone

Inlet/Outlet: 13.6mmVent/Drain: 7.5mmWith EPDM

300 3.0μm

500 5.0μm

0 0.4 0.8 1.2 1.6 2.0

al Pre

(mbar)

0 0.5 1.0 1.5 2.0 2.5

al Pre

(mbar)

PP PTFE

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

CHP Hose Barb capsule filters are designed to provide

liquid and high value-added liquid of lyophilized

powder and other pharmacy. Disposable filters can

help eliminate cleaning problems and extra validation

costs. 100% integrity testable prior to release ensures

high quality products.

Quality

environment

Specification

Support & Housing

Sealing Technology

Filtration Area

Pore Size, μm

Filter Media

PES/Nylon/PTFE/PP/MCE/

PVDF/GF

≥ 0.2 2 2m (2.2ft )

CHP Hose Barb Capsule Filter for Small Volume & High Value-added Pharmacy

0.22 μm PES/PTFE )

diminuta(ATCC19146) at a minimum challenge concentration7 2 of 1 x 10 CFU/cm .

Sterilization

3 autoclave cycles of 30 min at 123 ℃; steam-in-place sterilization

not recommended.

【】Code

CHP 022 DS 5

【【

0.1μm

0.22μm

001 0.01(for air)

NN Nylon

TL HydrophilicPTFE

T HydrophobicPTFE

GF Glass Fiber

V HydrophobicPVDF

100 1.0μm

045 0.45μm

Hose barb 13.6mm

∅7.5

Inlet/Outlet: 13.6mmVent/Drain: 7.5mmWith Silicone

Inlet/Outlet: 13.6mmVent/Drain: 7.5mmWith EPDM

300 3.0μm

500 5.0μm

0 0.4 0.8 1.2 1.6 2.0

al Pre

(mbar)

0 0.5 1.0 1.5 2.0 2.5

al Pre

(mbar)

PP PTFE

0.1μm

0.22μm

0.45μm

1.0μm

3.0μm

Quality

environment

Specification

Support & Housing

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Length

Inlet/Outlet Please refer to Ordering Information

2.5”, 5”, 10”

● Compact and sturdy construction

● Disposable design, easy change-out

● High pressure resistance

1/4" NPT Capsule Filter for Small Volume & High Value-added PharmacyCNP

Vent/Drainage Please refer to Ordering Information

2.5- inch

5-inch

10-inch

≥ ( )2 20.1m 1.1ft

Maximum Operating Pressure

Liquid: 3.5 bar 23℃, 3.0 bar @ 60℃ @

≥ ( )2 20.2m 2.2ft

≥ ( )2 20.3m 3.4ft

Air&Gas: 3.0 bar 23℃, 2.5 bar @ 60℃ @

PES/Nylon/PTFE/PP/GF/PVDF

CNP 1/4"NPT capsule filters are designed to provide

liquid and high value-added pharmacy. Disposable

filters can help eliminate cleaning problems and extra

validation costs. 100% integrity testable prior to release

Filter Media

9 10inch

【】Code

2.5inch

CNP 022 B 2

Filter 【【

0 0.2 0.4 0.6 0.8 1.0

0.45μm

al Pre

(mbar)

Water Flow Rate(L/min/2.5")

0 0.5 1.0 1.5 2.0 2.5

al Pre

(mbar)

PP PTFE

Inlet/Outlet:1/4"MNPTB

Vent/Drain: 1/8"MNPT

B type connectionH type for pipe threadconnection adapterSilicone O-ring

B type connectionH type for pipe threadconnection adapter

O-ringEPDM

0.1μm

0.22μm

1.0μm

0.45μm

3.0μm

5.0μm

0010.01(for air)

μmS PES

NN Nylon

Absolute PP

TLHydrophilic

THydrophobic

VHydrophobic

TAHydrophobic

PTFE for air

Multi-layer PPPF

GF Glass Fiber

NPT1/4"

H-type adapter

Ø67 Ø67

NPT1/4" NPT1/4"

Unit: mm

0.45μm

0.2μm

1.0μm

3.0μm

Quality

environment

Specification

Support & Housing

Sealing Technology

Dimensions

Filtration Area

Pore Size, μm

Length

Inlet/Outlet Please refer to Ordering Information

2.5”, 5”, 10”

● Compact and sturdy construction

● Disposable design, easy change-out

● High pressure resistance

1/4" NPT Capsule Filter for Small Volume & High Value-added PharmacyCNP

Vent/Drainage Please refer to Ordering Information

2.5- inch

5-inch

10-inch

≥ ( )2 20.1m 1.1ft

Liquid: 3.5 bar 23℃, 3.0 bar @ 60℃ @

≥ ( )2 20.2m 2.2ft

≥ ( )2 20.3m 3.4ft

Air&Gas: 3.0 bar 23℃, 2.5 bar @ 60℃ @

PES/Nylon/PTFE/PP/GF/PVDF

CNP 1/4"NPT capsule filters are designed to provide

liquid and high value-added pharmacy. Disposable

filters can help eliminate cleaning problems and extra

validation costs. 100% integrity testable prior to release

Filter Media

9 10inch

【】Code

2.5inch

CNP 022 B 2

Filter 【【

0 0.2 0.4 0.6 0.8 1.0

0.45μm

al Pre

(mbar)

0 0.5 1.0 1.5 2.0 2.5

al Pre

(mbar)

PP PTFE

Inlet/Outlet:1/4"MNPTB

Vent/Drain: 1/8"MNPT

B type connectionH type for pipe threadconnection adapterSilicone O-ring

B type connectionH type for pipe threadconnection adapter

O-ringEPDM

0.1μm

0.22μm

1.0μm

0.45μm

3.0μm

5.0μm

0010.01(for air)

μmS PES

NN Nylon

Absolute PP

TLHydrophilic

THydrophobic

VHydrophobic

TAHydrophobic

PTFE for air

Multi-layer PPPF

GF Glass Fiber

NPT1/4"

H-type adapter

Ø67 Ø67

NPT1/4" NPT1/4"

Unit: mm

0.45μm

0.2μm

1.0μm

3.0μm

F5P filters have good pressure resistance up to 350kpa,

2with filtration area of nearly 20 cm .They have high

throughputs under low pressure drops, and can be

reusable after autoclaved. F5P are designed to connect

easily to hose barbs, as well as 6:100 luer slip.

Quality

Specification

Support & Housing

Sealing Technology

Dimensions

Filtration Area

Removal Ratings, μm

Filter Media

Application

Compact and sturdy construction

Good pressure resistance

Disposable design, easy change-out

Filters produced in a controlled environment

Manufactured according to ISO9001 certified

Small-volume venting

Vent device for sensor

Small or medium batch filtration

Outer DiameterΦ65: for PTFE

Inlet/Outlet

Φ60: for PES/Nylon/PP/GF/PVDF/MCE

7~13 mm stepped hose barb connection with 6:100 Luer slip

≥ ( )2 219.6 cm 0.021 ft

Liquid: 3.5 bar @ 23 ,3.0Bar@ 60℃ ℃

Air&Gas: 3.0 bar @ 23 ,℃ ℃2.5Bar@ 60

PES/Nylon/PTFE/PP/GF/MCE/

【】Code【】Code

F5P 022 P 08N

Housing【】

Membrane【【

0 100 200 300 400 500

0.22μm

010 20 30 40 50

al Pre

(mbar)

al Pre

(mbar)

Water Flow Rate(mL/min) Nitrogen Flow Rate(L/min)

0.45μm

0.22μm

PES PTFE

Ø58.6

for PES/Nylon/MCE/PP/GF

Ø64.4

for PTFE

【】Prefilter【】Code

None__

Glass FiberG

08N 8 Non-Sterile

25 Non-Sterile

8 Sterile

25 Sterile

【】 Packing/

Box(pcs)

0.1μm

0 22. μm

0.45μm

100 1.0μm

NN Nylon

THydrophobic PTFE

V PVDF

GF Glass Fiber

TAHydrophobic PTFE for Air

TL HydrophilicPTFE for Liquid

0.45μm

F5P filters have good pressure resistance up to 350kpa,

2with filtration area of nearly 20 cm .They have high

throughputs under low pressure drops, and can be

reusable after autoclaved. F5P are designed to connect

easily to hose barbs, as well as 6:100 luer slip.

Quality

Specification

Support & Housing

Sealing Technology

Dimensions

Filtration Area

Removal Ratings, μm

Filter Media

Application

Compact and sturdy construction

Good pressure resistance

Disposable design, easy change-out

Small-volume venting

Vent device for sensor

Small or medium batch filtration

Outer DiameterΦ65: for PTFE

Inlet/Outlet

Φ60: for PES/Nylon/PP/GF/PVDF/MCE

7~13 mm stepped hose barb connection with 6:100 Luer slip

≥ ( )2 219.6 cm 0.021 ft

Liquid: 3.5 bar @ 23 ,3.0Bar@ 60℃ ℃

Air&Gas: 3.0 bar @ 23 ,℃ ℃2.5Bar@ 60

PES/Nylon/PTFE/PP/GF/MCE/

F5P 022 P 08N

Housing【】

Membrane【【

0 100 200 300 400 500

0.22μm

010 20 30 40 50

al Pre

(mbar)

al Pre

(mbar)

Water Flow Rate(mL/min) Nitrogen Flow Rate(L/min)

0.45μm

0.22μm

PES PTFE

Ø58.6

for PES/Nylon/MCE/PP/GF69.8

Ø64.4

for PTFE

【】Prefilter【】Code

None__

Glass FiberG

08N 8 Non-Sterile

25 Non-Sterile

8 Sterile

25 Sterile

【】 Packing/

Box(pcs)

0.1μm

0 22. μm

0.45μm

100 1.0μm

NN Nylon

THydrophobic PTFE

V PVDF

GF Glass Fiber

TL HydrophilicPTFE for Liquid

0.45μm

®Easiprep syringe filters are charaterised by various membranes,

diameters, pore sizes and connectors. These filters are disposable,

ideal for clarification, sterile filtration, venting and other demands

in laboratory applications.

®Easiprep φ5/ Syringe Filterφ13/φ20/φ25/φ33

Quality

Application

Clarification and particle removal

Sterile filtration

Venting and gas filtration

Chromatography sample preparation●

Low hold-up volume and low extractables

Various inlet/outlet connectors available

Gamma irradiated or EO sterilized

Various membrane diameter available

Broad chemical compatibility

Available in non-sterile and sterile version

022 P 08N

Housing【】

Membrane【【【】Prefilter【】Code

Glass FiberG

1HN 100 Non-Sterile

200 Non-Sterile

50 Sterile, EO

100 Sterile, EO

【】 Packing/

Box(pcs)

0.1μm

0 22. μm

0.45μm

100 1.0μm

NN Nylon

THydrophobic PTFE

V Hydrophobic PVDF

GF Glass Fiber

TL Hydrophilic PTFE

【】Code 【】Connection

Inlet: female luer lockOutlet: male luer unlock

Inlet: male luer unlockOutlet: male luer unlock

Inlet: female luer lockOutlet: male luer lock

300 3.0μm

500 5.0μm

【】Code

Diameter【】

20 20mm

25 25mm

33 33mm

φ13 φ20 φ25 φ33

13 mm 20 mm 25 mm 33 mm

PP/HDPE ABS PP/HDPE PP/HDPE

21.3 cm 23.1 cm 24.9 cm 28.5 cm

16.0mm * 23.0mm 23.0mm*23.5mm 28.0mm*24.3mm 40.0mm*30.3mm

＜ 100 l μ ＜ 150μl ＜ 250μl ＜ 350μl

Inlet:

Outlet:

131 ℃(267.8℉)

Autoclave at 123℃ at 1 bar for 20 minutes(253.4℉@14.5psi)

＜ 0.25 EU/ml as determined by the LAL test

Membrane

Diameter

Housing

Filtration

Dimension

Hold-up

Volume

Sterilization

5.2 bar 3.5 bar 5.2bar 5.2 bar

Maximum

Operating

Pressure

Female Luer Lock

Male Luer Slip

Female Luer Lock

Male Luer Lock

Female Luer Lock

Male Luer Slip

Female Luer Lock

Male Luer Lock

Male Luer Slip

Female Luer Lock

Male Luer Slip

Please contact us for more details.

Specification

50 Sterile, Gamma

100 Sterile, Gamma

20.19 cm

12.0mm * 17.2mm

＜ 15 l μ

4.0 bar

Female Luer Slip

Male Luer Slip

®Easiprep syringe filters are charaterised by various membranes,

diameters, pore sizes and connectors. These filters are disposable,

ideal for clarification, sterile filtration, venting and other demands

in laboratory applications.

®Easiprep φ5/ Syringe Filterφ13/φ20/φ25/φ33

Quality

Application

Clarification and particle removal

Sterile filtration

Venting and gas filtration

Chromatography sample preparation●

Low hold-up volume and low extractables

Various inlet/outlet connectors available

Gamma irradiated or EO sterilized

Various membrane diameter available

Broad chemical compatibility

Available in non-sterile and sterile version

022 P 08N

Housing【】

Membrane【【【】Prefilter【】Code

Glass FiberG

1HN 100 Non-Sterile

200 Non-Sterile

50 Sterile, EO

100 Sterile, EO

【】 Packing/

Box(pcs)

0.1μm

0 22. μm

0.45μm

100 1.0μm

NN Nylon

THydrophobic PTFE

V Hydrophobic PVDF

GF Glass Fiber

TL Hydrophilic PTFE

【】Code 【】Connection

Inlet: female luer lockOutlet: male luer unlock

Inlet: male luer unlockOutlet: male luer unlock

Inlet: female luer lockOutlet: male luer lock

300 3.0μm

500 5.0μm

【】Code

Diameter【】

20 20mm

25 25mm

33 33mm

φ13 φ20 φ25 φ33

13 mm 20 mm 25 mm 33 mm

PP/HDPE ABS PP/HDPE PP/HDPE

21.3 cm 23.1 cm 24.9 cm 28.5 cm

16.0mm * 23.0mm 23.0mm*23.5mm 28.0mm*24.3mm 40.0mm*30.3mm

＜ 100 l μ ＜ 150μl ＜ 250μl ＜ 350μl

Inlet:

Outlet:

131 ℃(267.8℉)

Autoclave at 123℃ at 1 bar for 20 minutes(253.4℉@14.5psi)

＜ 0.25 EU/ml as determined by the LAL test

Membrane

Diameter

Housing

Filtration

Dimension

Hold-up

Volume

Sterilization

5.2 bar 3.5 bar 5.2bar 5.2 bar

Maximum

Operating

Pressure

Female Luer Lock

Male Luer Slip

Female Luer Lock

Male Luer Lock

Female Luer Lock

Male Luer Slip

Female Luer Lock

Male Luer Lock

Male Luer Slip

Female Luer Lock

Male Luer Slip

Please contact us for more details.

Specification

50 Sterile, Gamma

100 Sterile, Gamma

20.19 cm

12.0mm * 17.2mm

＜ 15 l μ

4.0 bar

Female Luer Slip

Male Luer Slip

Application

● Good mechanical strength

● Resistant to alkaline solutions and most

organic solvent

Features

● Alkali

● Transfer membrane

Application

Features

● Low protein binding and low extractables

● Terminal filtration

● Environment analysis

Application

Features

● Very suitable for biologics filtration

● Clarification

● Biologics

● Microbiological analysis

● Liquids contain protein

● SDI membrane

Application

Features

● Naturally hydrophobic

● Good heat resistance

● Gases

● Corrosive liquid

Application

Features

● Good heat and chemical

resistance

● Gases

● Biologics

MP 045 293 25

Size【】

Membrane【【

This information is a guide to the Part No. structure and possible options. For availability of specific options and housing

details, please contact ANOW.

【】【】Code

【】 Packing/

Box(pcs)

Water flow2 rate(ml/cm min

△p=0.1Mpa)20 10 16 4 35 15 30 6 7 3

Sterilization By autoclave at 123 (253.4 ) or EO℃ ℉)

MCE Nylon PES PTFE PVDFMaterial

Pore size

(μm)0.45 0.22 0.45 0.22 0.45 0.22 0.45 0.22 0.45 0.22

Bubble point(mbar)

Water@23 (73.4 )℃ ℉ 60%IPA@23 (73.4 )℃ ℉

150 310 150 310 250 350 60 100 40 70

Thickness

(μm)85-110 90-140 110-140 150-250 90-100

pH 3.5-8.0 6-13 1-14 1-14 2-10

0.1μm

0 22. μm

0.45μm

065 0.65μm

0 8. μm

1.2μm

300 3.0μm

150 150mm

293 293mm

300 300mm

WithoutN

NN Nylon

THydrophobic

TLHydrophilic

V PVDF

Interlayer Paper

Application

● Good mechanical strength

● Resistant to alkaline solutions and most

organic solvent

Features

● Alkali

Application

Features

● Low protein binding and low extractables

● Terminal filtration

● Environment analysis

Application

Features

● Very suitable for biologics filtration

● Clarification

● Biologics

● Microbiological analysis

● Liquids contain protein

● SDI membrane

Application

Features

● Good heat resistance

● Gases

Application

Features

● Good heat and chemical

resistance

● Gases

● Biologics

MP 045 293 25

Size【】

Membrane【【

【】【】Code

【】 Packing/

Box(pcs)

Water flow2 rate(ml/cm min

△p=0.1Mpa)20 10 16 4 35 15 30 6 7 3

Sterilization By autoclave at 123 (253.4 ) or EO℃ ℉)

MCE Nylon PES PTFE PVDFMaterial

Pore size

(μm)0.45 0.22 0.45 0.22 0.45 0.22 0.45 0.22 0.45 0.22

Bubble point(mbar)

Water@23 (73.4 )℃ ℉ 60%IPA@23 (73.4 )℃ ℉

150 310 150 310 250 350 60 100 40 70

Thickness

(μm)85-110 90-140 110-140 150-250 90-100

pH 3.5-8.0 6-13 1-14 1-14 2-10

0.1μm

0 22. μm

0.45μm

065 0.65μm

0 8. μm

1.2μm

300 3.0μm

150 150mm

293 293mm

300 300mm

WithoutN

NN Nylon

THydrophobic

TLHydrophilic

V PVDF

Interlayer Paper

HY series sanitary housings are developed specifically for liquid filtration

in the pharmaceutical, food&beverage, microelectronic and chemical

industry.

● Corrosion resistance and durability with 316L/304 stainless steel

wetted parts and mirror-polished inner and outer surface

● Enhanced cleanability and microbiological safety due to crevice-free,

polished and hygienic design

● Multiple choices for connections

● Single-round and multi-round filter housings are available with

cartridges of 10/ 20/ 30/ 40 inch

● Cost-effective without sacrificing quality and performance

Features and BenefitsSpecification

Series Stainless Steel Filter Housing for Sanitary Liquid FiltrationHY

Operator-friendly and long service life

Low adsorption, easy clean-up and back

washing

No shedding and no leakage

Good heat and corrosion resistance

Suitable for CIP and SIP

-marked●

6bar(87psi)

Cartridge Capacity

1-round, 3-round, 5-round, 7-round, 9-round, 11-round...

Connection

Inlet/Outlet

Gauge Port

Cartridge 222/Fin, 226/Fin, DOE

Flange/ Tri-Clamp

Housing

Seal Silicone/EPDM/Viton/TEV

316L/304 stainless steel

304 stainless steel

140℃(284℉)

HY 001 10

【】Code 【】【】Code

【【

Nominal Dimensions in mm(inches)-for specific dimensions, please contact ANOW.

Single-round standard housings

225（8.9）

350（13.8）

600（23.6）

850（33.5）

84（3.3）

110（4.3）

CodeCartridge

LengthA B C

127（5）

254（10）

508（20）

762（30）

111.6（4.0）

200（7.9）

Housing Material

C SUS304

D SUS316L

Cartridge Capacity

10inch

20inch

30inch

40inch

【 eal】S【】Code

【】【】Code

Connection

A 222/Fin

C 226/Fin S

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

20 DN20

Inlet/Outlet Connection

40 DN40

HY series sanitary housings are developed specifically for liquid filtration

in the pharmaceutical, food&beverage, microelectronic and chemical

industry.

● Enhanced cleanability and microbiological safety due to crevice-free,

polished and hygienic design

Series Stainless Steel Filter Housing for Sanitary Liquid FiltrationHY

Low adsorption, easy clean-up and back

washing

Suitable for CIP and SIP

-marked●

6bar(87psi)

Cartridge Capacity

1-round, 3-round, 5-round, 7-round, 9-round, 11-round...

Connection

Inlet/Outlet

Gauge Port

Flange/ Tri-Clamp

Housing

304 stainless steel

140℃(284℉)

HY 001 10

【【

225（8.9）

350（13.8）

600（23.6）

850（33.5）

84（3.3）

110（4.3）

CodeCartridge

LengthA B C

127（5）

254（10）

508（20）

762（30）

111.6（4.0）

200（7.9）

Housing Material

C SUS304

D SUS316L

Cartridge Capacity

10inch

20inch

30inch

40inch

【】【】Code

Connection

A 222/Fin

C 226/Fin S

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

20 DN20

40 DN40

Features and Benefits Specification

Cartridge Capacity

Connection

Inlet/Outlet

Gauge Port

Flange/ Tri-Clamp

Housing

304 stainless steel

6bar(87psi)

140℃(284℉)

HK Series Stainless Steel Filter Housing for Gas&Air Filtration

HK series sanitary housings are developed specifically for gas&air

filtration in

● Enhanced cleanability and microbiological safety due to

crevice-free, polished and hygienic design

pharmaceutical, food&beverage, microelectronic and

chemical industry.

Low adsorption

Mirror-polished inner and outer surface

-marked●

1-round, 3-round, 5-round, ...

HK 001 10

【【

Housing Material

C SUS304

D SUS316L

Cartridge Capacity

10inch

20inch

30inch

40inch

【】【】Code

Connection

A 222/Fin

C 226/Fin S

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

20 DN20

25 DN25

185（7.3）

310（2.2）

560（22.0）

810（31.9）

1060(41.7)

75（3.0）

158（6.2）

Code Cartridge Length A B C

127（5）

254（10）

508（20）

762（30）

1016(40)

101.6（4.0）

250（9.8）

20（0.8）

5 5inch

Cartridge Capacity

Connection

Inlet/Outlet

Gauge Port

Flange/ Tri-Clamp

Housing

304 stainless steel

6bar(87psi)

140℃(284℉)

HK Series Stainless Steel Filter Housing for Gas&Air Filtration

HK series sanitary housings are developed specifically for gas&air

filtration in

● Enhanced cleanability and microbiological safety due to

pharmaceutical, food&beverage, microelectronic and

chemical industry.

Low adsorption

-marked●

1-round, 3-round, 5-round, ...

HK 001 10

【【

Housing Material

C SUS304

D SUS316L

Cartridge Capacity

10inch

20inch

30inch

40inch

【】【】Code

Connection

A 222/Fin

C 226/Fin S

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

20 DN20

25 DN25

185（7.3）

310（2.2）

560（22.0）

810（31.9）

1060(41.7)

75（3.0）

158（6.2）

Code Cartridge Length A B C

127（5）

254（10）

508（20）

762（30）

1016(40)

101.6（4.0）

250（9.8）

20（0.8）

5 5inch

Connection

Inlet/Outlet Flange/ Tri-Clamp

6bar(87psi)

140℃(284℉)

HM Series Filter Sanitary Disc Holder

HM series sanitary housings are developed specifically for

liquid and gas filtration in the

Corrosion resistance and durability with 316L/304

stainless steel wetted parts and mirror-polished inner

and outer surface

PTFE lining is available to provide advanced protection

from corrosion

pharmaceutical, food&beverage,

microelectronic and chemical industry.

Long service life

Low adsorption

Easy installation, clean up, and adjustment

-marked●

Housing

Membrane Diameter

47mm, 90mm, 100mm, 142mm, 150mm, 293mm

HM 293

【【

Housing Material

C SUS304

D SUS316L

FilterDiameter 【 eal】S【】Code

【】【】Code

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

Layers

293mm Disc Filter Holder

293 294（11.5） 15（0.6） 15（0.6） 150（5.9）

Code Membrane Diameter A C D E

293（11.5） 360（14.2）

15 DN15

20 DN20

25 DN25

Connection

Inlet/Outlet Flange/ Tri-Clamp

6bar(87psi)

140℃(284℉)

HM Series Filter Sanitary Disc Holder

HM series sanitary housings are developed specifically for

liquid and gas filtration in the

Corrosion resistance and durability with 316L/304

stainless steel wetted parts and mirror-polished inner

and outer surface

PTFE lining is available to provide advanced protection

from corrosion

pharmaceutical, food&beverage,

microelectronic and chemical industry.

Long service life

Low adsorption

Easy installation, clean up, and adjustment

-marked●

Housing

Membrane Diameter

47mm, 90mm, 100mm, 142mm, 150mm, 293mm

HM 293

【【

Housing Material

C SUS304

D SUS316L

FilterDiameter 【 eal】S【】Code

【】【】Code

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

Layers

293mm Disc Filter Holder

293 294（11.5） 15（0.6） 15（0.6） 150（5.9）

Code Membrane Diameter A C D E

293（11.5） 360（14.2）

15 DN15

20 DN20

25 DN25

Connection

6bar(87psi)

140℃(284℉)

HT Series Titanium Filter Housing

HT series sanitary housings are developed for liquid filtration in

the pharmaceutical, food and beverage, microelectronic industry,

especially suitable for carbon removal, high temperature and

corrosive liquid filtration in infusion and injection manufacturing.

● Corrosion resistance and durability with 316L/304 stainless

steel wetted parts and mirror-polished inner and outer surface

● Use titanium powder sintered filter

● Side-in and down-out structure, with multiple choices for inlet

and outlet connections

● Easy clean up and backwash

Long service life

Low adsorption

Good corrosion and acid and alkali resistance

Titanium filter is reusable

-marked●

Housing

Cartridge Capacity

1-round, 3-round, 5-round, 7-round, 9-round, 11-round

Inlet/Outlet

Cartridge

Flange/ Tri-Clamp

Gauge Port Flange/ Tri-Clamp

M20/M30 Thread

HT 011

【【

Housing Material

C SUS304

D SUS316L

Cartridge Capacity 【 eal】S【】Code

【】【】Code

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

SizeConnection

25 DN25

38 DN38

40 DN40

10inch

20inch

30inch

40inch

5-Round standard housing of 20”

20 508（20） 440（17.3） 420（16.5） 200（7.9）

CodeCartridge

HeightA B C D E

200（7.9） 290（11.4）

14（0.6）

121（4.8）

013 13

50 DN50

Connection

6bar(87psi)

140℃(284℉)

HT Series Titanium Filter Housing

HT series sanitary housings are developed for liquid filtration in

the pharmaceutical, food and beverage, microelectronic industry,

especially suitable for carbon removal, high temperature and

corrosive liquid filtration in infusion and injection manufacturing.

● Corrosion resistance and durability with 316L/304 stainless

steel wetted parts and mirror-polished inner and outer surface

● Use titanium powder sintered filter

● Side-in and down-out structure, with multiple choices for inlet

and outlet connections

● Easy clean up and backwash

Long service life

Low adsorption

Good corrosion and acid and alkali resistance

Titanium filter is reusable

-marked●

Housing

Cartridge Capacity

1-round, 3-round, 5-round, 7-round, 9-round, 11-round

Inlet/Outlet

Cartridge

Flange/ Tri-Clamp

Gauge Port Flange/ Tri-Clamp

M20/M30 Thread

HT 011

【【

Housing Material

C SUS304

D SUS316L

【】【】Code

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

SizeConnection

25 DN25

38 DN38

40 DN40

10inch

20inch

30inch

40inch

5-Round standard housing of 20”

20 508（20） 440（17.3） 420（16.5） 200（7.9）

CodeCartridge

HeightA B C D E

200（7.9） 290（11.4）

14（0.6）

121（4.8）

013 13

50 DN50

Connection

6bar(87psi)

140℃(284℉)

Cartridge Capacity

Fast filtration, long service life

Low adsorption, no shedding and no leakage

-marked●

HG Series Sanitary In-line Liquid and Gas Filter Housing

HG series sanitary housings are developed specifically for liquid filtration

in the

such as pure water, ultra pure water, drinking water, distilled water,

acid and alkali, and other chemicals.

Corrosion resistance and durability with 316L/304 stainless steel wetted

parts and mirror-polished inner and outer surface

Enhanced cleanability and microbiological safety due to

Multiple choices for inlet and outlet connections

Single-round and multi-round filter housings are available

pharmaceutical, food&beverage, microelectronic and chemical

industry

Housing

1-round, 3-round, 5-round

Inlet/Outlet

Cartridge

304 stainless steel

Flange/ Tri-Clamp

222/Fin, 226/Fin, DOE

127（5）

254（10）

508（20）

762（30）

225（8.9）

350（13.8）

600（23.6）

850（33.5）

44（1.7）

101.6（4.0）

Code Cartridge Length A B D

HG 001

【【Housing Material

C SUS304

D SUS316L

【】【】Code

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

Inlet/Outlet

Connection Size

Connection

10inch

20inch

30inch

222/Fin

226/Fin

5 5inch DN15

Connection

6bar(87psi)

140℃(284℉)

Cartridge Capacity

Fast filtration, long service life

Low adsorption, no shedding and no leakage

-marked●

HG Series Sanitary In-line Liquid and Gas Filter Housing

HG series sanitary housings are developed specifically for liquid filtration

in the

such as pure water, ultra pure water, drinking water, distilled water,

acid and alkali, and other chemicals.

Corrosion resistance and durability with 316L/304 stainless steel wetted

parts and mirror-polished inner and outer surface

Enhanced cleanability and microbiological safety due to

Multiple choices for inlet and outlet connections

Single-round and multi-round filter housings are available

pharmaceutical, food&beverage, microelectronic and chemical

industry

Housing

1-round, 3-round, 5-round

Inlet/Outlet

Cartridge

304 stainless steel

Flange/ Tri-Clamp

222/Fin, 226/Fin, DOE

127（5）

254（10）

508（20）

762（30）

225（8.9）

350（13.8）

600（23.6）

850（33.5）

44（1.7）

101.6（4.0）

Code Cartridge Length A B D

HG 001

【【Housing Material

C SUS304

D SUS316L

【】【】Code

E EPDM

V Viton

Silicone

【】【】Code

Inlet/ Outlet

K Tri-Clamp

F Flange

【】【】Code

Inlet/Outlet

Connection Size

Connection

10inch

20inch

30inch

222/Fin

226/Fin

5 5inch DN15

Classification Name Nylon PVDF PTFE PES PP MCE Silicone EPDM Viton TEV

Acetic Acid NR R R NR R LR LR R NR R

Hydrochloric Acid (conc.) NR R R R R NR NR NR NR R

Hydrochloric Acid (6N) NR R R R R NR NR NR R R

Nitric Acid (conc.) NR R R - R NR NR NR R R

Nitric Acid (6N) NR R R - R NR LR NR R R

Phosphoric Acid (conc.) NR R R - R NR NR R R R

Sulfuric Acid (conc.) NR R R NR R NR NR NR R R

Hydrofluoric Acid (6N) NR R R - NR NR NR NR - R

Ammonium Hydroxide (1N) R LR R R R R R R R R

Ammonium Hydroxide (3N) R NR R R R NR R LR LR R

Potassium Hydroxide (3N) R LR R R R NR LR R R R

Sodium Hydroxide (3N) R LR R R R NR R R R R

Sodium Hydroxide (6N) R NR R R R NR R R R R

Alcohols

Amyl Alcohol R R R R R NR NR R R R

Benzyl Alcohol (100%) R R R R R NR LR R R R

Butanol R R R R R R R R LR R

Isopropanol R R R R R - R R R R

Methanol LR R R R R LR R R NR R

Ketones

Acetone R LR R NR R NR NR R NR R

Cyclohexanone - LR R NR R NR NR NR NR R

Methyl Ethyl Ketone LR LR R - R - NR R NR R

Methyl Isobutyl Ketone LR LR R NR R - NR R NR R

Cottonseed R R R - R - R R R

Lubricant R R R NR R - R R R R

Peanut R R R - R - R R R R

Sesame R R R R R - R R R R

Aromatic

Hydrocarbons

Benzene LR LR R LR NR R NR NR R R

Toluene NR LR R NR NR R NR NR R R

Xylene LR LR R NR NR R NR NR R R

Halogenated

Hydrocarbons

Carbon Tetrachloride LR LR R LR LR NR NR NR R R

Chloroform LR LR R NR LR NR NR NR R R

Ethylene Dichloride LR LR R NR LR R NR NR LR R

Freon TF R R R R LR R NR NR R R

Freon TMC LR LR R NR LR R NR NR LR R

Methylene Dichloride NR LR R NR LR NR NR NR LR R

Perchloroethylene - LR R LR LR R NR NR R R

Trichloroethylene LR NR R LR LR R NR NR R R

Glycols

Ethylene Glycol R R R LR R - R R R R

Glycerol R R R LR R R R R R R

Propylene Glycol R R R LR R R R R

Ethers

Ethyl Ether NR R R R LR NR LR NR NR R

Isopropyl Ether - R R - R NR NR NR NR R

Dioxane R R R - R NR NR NR NR R

Tetrahydrofuran NR LR R NR LR NR NR NR NR R

Esters

Amyl Acetate LR R R - R NR NR R NR R

Butyl Acetate LR R R - LR NR NR R R R

Cellosolve Acetate - R R R R NR NR R NR R

Ethyl Acetate LR R R LR LR NR R R R R

Methyl Acetate LR R R NR R NR - R R R

Isopropyl Acetate - R R R R NR LR R NR R

Connections

Aniline LR R R NR LR - NR R R R

Dimethyl Formamide R NR R NR R - R R NR R

Formaldehyde (37%) R R R R R - R R NR R

Gasoline LR LR LR R LR R NR R R R

Hexane (dry) - LR LR LR LR R NR NR R R

Kerosene - R R R R - NR NR R R

Phenol R R R NR R R NR NR R R

Pyridine LR R R NR LR NR NR R NR R

Turpentine - R R R LR - NR NR R R

Water R R R R R R LR R R R

Acetonitrile LR R R R LR NR - R NR R

Nickel Sulfate Solution R R R - R - R R - R

Notes: This table is intended to serve as a guide only. Accuracy cannot be guaranteed. Users are responsible

for verifying chemical compatibility under their own conditions of use. Chemical compatibility is affected by

many variables including temperature, pressure, concentration, and chemical purity.

R: Resistance;

LR: Limited resistance;

NR: No resistance;

“-”: No data available.

Miscellaneous

222/Fin 222/Flat 226/Fin 226/Flat DOE

Acetic Acid NR R R NR R LR LR R NR R

Hydrochloric Acid (conc.) NR R R R R NR NR NR NR R

Hydrochloric Acid (6N) NR R R R R NR NR NR R R

Nitric Acid (conc.) NR R R - R NR NR NR R R

Nitric Acid (6N) NR R R - R NR LR NR R R

Phosphoric Acid (conc.) NR R R - R NR NR R R R

Sulfuric Acid (conc.) NR R R NR R NR NR NR R R

Hydrofluoric Acid (6N) NR R R - NR NR NR NR - R

Ammonium Hydroxide (1N) R LR R R R R R R R R

Ammonium Hydroxide (3N) R NR R R R NR R LR LR R

Potassium Hydroxide (3N) R LR R R R NR LR R R R

Sodium Hydroxide (3N) R LR R R R NR R R R R

Sodium Hydroxide (6N) R NR R R R NR R R R R

Alcohols

Amyl Alcohol R R R R R NR NR R R R

Benzyl Alcohol (100%) R R R R R NR LR R R R

Butanol R R R R R R R R LR R

Isopropanol R R R R R - R R R R

Methanol LR R R R R LR R R NR R

Ketones

Acetone R LR R NR R NR NR R NR R

Cyclohexanone - LR R NR R NR NR NR NR R

Methyl Ethyl Ketone LR LR R - R - NR R NR R

Methyl Isobutyl Ketone LR LR R NR R - NR R NR R

Cottonseed R R R - R - R R R

Lubricant R R R NR R - R R R R

Peanut R R R - R - R R R R

Sesame R R R R R - R R R R

Aromatic

Hydrocarbons

Benzene LR LR R LR NR R NR NR R R

Toluene NR LR R NR NR R NR NR R R

Xylene LR LR R NR NR R NR NR R R

Halogenated

Hydrocarbons

Carbon Tetrachloride LR LR R LR LR NR NR NR R R

Chloroform LR LR R NR LR NR NR NR R R

Ethylene Dichloride LR LR R NR LR R NR NR LR R

Freon TF R R R R LR R NR NR R R

Freon TMC LR LR R NR LR R NR NR LR R

Methylene Dichloride NR LR R NR LR NR NR NR LR R

Perchloroethylene - LR R LR LR R NR NR R R

Trichloroethylene LR NR R LR LR R NR NR R R

Glycols

Ethylene Glycol R R R LR R - R R R R

Glycerol R R R LR R R R R R R

Propylene Glycol R R R LR R R R R

Ethers

Ethyl Ether NR R R R LR NR LR NR NR R

Isopropyl Ether - R R - R NR NR NR NR R

Dioxane R R R - R NR NR NR NR R

Tetrahydrofuran NR LR R NR LR NR NR NR NR R

Esters

Amyl Acetate LR R R - R NR NR R NR R

Butyl Acetate LR R R - LR NR NR R R R

Cellosolve Acetate - R R R R NR NR R NR R

Ethyl Acetate LR R R LR LR NR R R R R

Methyl Acetate LR R R NR R NR - R R R

Isopropyl Acetate - R R R R NR LR R NR R

Connections

Aniline LR R R NR LR - NR R R R

Dimethyl Formamide R NR R NR R - R R NR R

Formaldehyde (37%) R R R R R - R R NR R

Gasoline LR LR LR R LR R NR R R R

Hexane (dry) - LR LR LR LR R NR NR R R

Kerosene - R R R R - NR NR R R

Phenol R R R NR R R NR NR R R

Pyridine LR R R NR LR NR NR R NR R

Turpentine - R R R LR - NR NR R R

Water R R R R R R LR R R R

Acetonitrile LR R R R LR NR - R NR R

Nickel Sulfate Solution R R R - R - R R - R

Notes: This table is intended to serve as a guide only. Accuracy cannot be guaranteed. Users are responsible

for verifying chemical compatibility under their own conditions of use. Chemical compatibility is affected by

many variables including temperature, pressure, concentration, and chemical purity.

R: Resistance;

LR: Limited resistance;

NR: No resistance;

“-”: No data available.

Miscellaneous

222/Fin 222/Flat 226/Fin 226/Flat DOE

www.anowfilter.com

Biopharmaceutical

Filtration Solutions

Hangzhou Anow Microfiltraion Co.,Ltd.Office：Room 901-903, Central Building, No.271, Hushu South Road, Hangzhou, China

Plant: Qingming Bridge, Xindeng Industrial Zone, Fuyang, Hangzhou, China

Tel: +86-571-883-70389

Fax: +86-571-883-70399

Website: www.anowfilter.com

E-mail: [email protected]

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Biopharmaceutical Filtration Solutions · filters. provides professional assistances to liquid and...

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