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Transcript of Bionics Certificate Future Is Becoming Reality… · Bionics Certificate The price of bionic...
Weekly Barometer 25 janvier 2012
Bionics Certificate – Future Is Becoming Reality
January 2018
ATONRÂ PARTNERS SA 12, Rue Pierre Fatio – 1204 GENEVA – SWITZERLAND - Tel: + 41 22 310 15 01 http://www.atonra.ch
Bionics Certificate 2
Investment Case
➢ Innovations in the fields of medicine, artificial intelligence, robotics and sensors are finally giving a
new life to medical technologies and are making human enhancement a reality
➢ Bionics, which is taking on human body dysfunctions and disabilities and, more globally, helping
improve the wellness and lifespan of the world population, benefits from long-term drivers:
✓ an ageing world population and a shortage of donated organs
✓ major technology breakthroughs leading to an impressive product pipeline
✓ an improving outlook for the reimbursement of bionic devices by insurers or health agencies
➢ Bionics is not only about next-gen prosthetics, it also covers artificial organs, wearable devices,
surgical and medical robots, synthetic biology, biotechnology and artificial intelligence
Bionics Certificate details
✓ Issuing bank: Natixis, Calculation agent: Natixis SA
✓ ISIN: XS1317063912
✓ Currency: USD
✓ Fees: 1.65% management fee + 15% performance fee, high water mark
✓ Bloomberg ticker: NXSRBION
Bionics Certificate 3
Bionics
limbs
Artificial organs
Medical wearables
Surgery robots
3D printing
Exoskeletons
Artificial intelligence
Synthetic
biology
Bionics Certificate 4
Bionics Is The Merger Between Biology And Electronics (I)
Fixing our body dysfunctions Leveraging on Life mechanisms
➢ Replacing limbs and organs ➢ Using them for specific purposes
➢ Monitoring metabolism ➢ In particular for surgery
Seconding humans Improving health
Bionics Certificate
➢ The first artificial organ was designed in 1943 to
replace a deficient kidney: a dialyzer
➢ Now a Microchip filter (1) used in an artificial
kidney (2) is to be tested in humans by the end of
2017 and might keep a patient off dialysis
➢ Today, 60-70% of human body functionalities
can be artificially performed as demonstrated by
Frank, the bionic man Bertolt Meyer designed in
2013
➢ Still missing: digestive system, liver, skin and brain
5
Artificial Organs Turning Into Everyday Wearable Devices
BIONIC BODY PARTS
Bionics Certificate
➢ Medical technology innovations are made possible thanks to advances in:
➢ Research is performed on extending Moore’s Law by optimizing chip technology
➢ Quantum computing will further extend Moore’s law exponentially
6
ChipsArtificial
intelligence
Genetic Modification
Precision Sugery
4D Printing Crowdsourcing
Genomics
Virtual
Reality
When Moore’s Law Comes To The Labs
Nanotechnology
Bionics Certificate
Bionics And Artificial Organs Address A Huge Market
7
About 15% of the global population
have a disability
285 million people are
visually impaired
360 million people have
disabling hearing loss
>120k people in the US are
waiting for lifesaving
organ transplants
Source: AtonRa Partners, WHO
Bionics Certificate
➢ According to the UN, the population aged 60 years or over will grow from 900M in 2015 to 1.4Bn in
2030, while the population >80 years old will grow from 125M to 201M
➢ The bulk of the growth comes from Asia: 66% growth of people >60 years old
8
Elderly Population Increasing Exponentially
Bionics Certificate
➢ The price of bionic devices has been unsurprisingly high until now (between $50,000 and $150,000
for an eye or limb device and surgery)
➢ Encouragingly, coverage by Medicare in the US seems to be heading in the right direction
✓ the health agency recently paid for a $144,000 bionic eye
9
…But Likely To Gradually Expand As Benefits Outweigh Declining Costs
➢ Declining costs and social welfare: a major catalyst for expanded health coverage
✓ some of the technologies used will mature over the years and become less costly
✓ a bionic device can allow people to keep working and return to work more quickly
Health Coverage Of Bionic Devices Has Been An issue…
Bionics Certificate 10
Bionics Expected To Grow At A Fast pace
CAGR 17-23
Artificial Organs & Bionics ($38.7B)
Medical Robots ($17.6B)
Exoskeletons ($2.8B)
Wearable Medical Devices ($14.4B)
Synthetic Biology ($37.2B)
Healthcare 3D printing ($2.5B)
45.2%
27.7%
18.3%
7.5%
9%
22%
MedTech ($522B) 5.6%
AtonRâ
Bionics
Source: Grand View Research, Marketsandmarkets, Mordor Intelligence, Chief Observer, Infoholic
A $113B MARKET BY 2023
Bionics Certificate 11
Bionic Limbs
Bionic Hearts
Exoskeletons
Bionic Ears
Bionic Brains
Bionic Eyes
Segmenting The Bionics Market
Bionics Certificate
➢ Prosthetics are now on their way to offering real limb replacement…
➢ A cochlear implant does the work of damaged parts of the inner ear…
➢ A bionic eye complements impaired retinas…
➢ Sensors deliver electrical signals to the nervous system, enabling the brain to feel / hear / see
12
The Advent Of Brain-Connected Prosthetics
Bionics Certificate
➢ Surgical robots: console, surgical arms, monitoring systems
➢ Telemedicine Robots
➢ Artificial Intelligence applications for diagnosis, monitoring or learning new surgical procedures
➢ Rehabilitation robots, exoskeletons
➢ Robots working in sterile IV (intravenous) preparation rooms.
13
Medical Robots – New Means For Better Medicine
Bionics Certificate 14
Therapeutic Wearables
Pain management device,
insulin/glucose monitoring devices,
rehabilitation devices (…)
Diagnostic Devices
Vital sign monitoring devices, electrocardiograph, obstetric devices, neuromonitoring devices (…)
Home Healthcare
Remote patient monitoring -
technological advancements in medical devices provide higher
accuracy and ease of use
Telehealth
Gaining traction as a way to engage patients and also
address care outside of hospitals
MiniMed530G
(Medtronic) monitors glucose
levels and dispenses insulin
FreeStyle Libre Flash Glucose
Monitoring System from Abbott
The Zensor: detection and
capture of five common arrhythmias
Wearable Medical Devices: An Important Link In The Chain
Bionics Certificate
➢ Synthetic biology is the engineering of biology: the synthesis of complex, biologically based
systems which display functions that do not exist in nature
➢ While products that utilize synthetic biology are yet to be commercialized, this market is set to
literally explode in the next few years driven by demand for improved drugs and vaccines
➢ Key constraints are mostly ethics and bio-security/safety, as synthetic biology can be misused
15
Synthetic Biology: Making The Impossible Possible
Bionics Certificate 16
Increased accuracy
Safety checks
Benefits vs. Costs
This report has been produced by the organizational unit responsible for investment research (Research
unit) of AtonRâ Partners and sent to you by the company sales representatives.
As an internationally active company, AtonRâ Partners SA may be subject to a number of provisions in
drawing up and distributing its investment research documents. These regulations include the Directives
on the Independence of Financial Research issued by the Swiss Bankers Association.
Although AtonRâ Partners SA believes that the information provided in this document is based onreliable sources, it cannot assume responsibility for the quality, correctness, timeliness or completenessof the information contained in this report.
The information contained in these publications is exclusively intended for a client base consisting ofprofessionals or qualified investors. It is sent to you by way of information and cannot be divulged to athird party without the prior consent of AtonRâ Partners.
While all reasonable effort has been made to ensure that the information contained is not untrue ormisleading at the time of publication, no representation is made as to its accuracy or completeness and itshould not be relied upon as such.
Past performance is not indicative or a guarantee of future results. Investment losses may occur, andinvestors could lose some or all of their investment.
Any indices cited herein are provided only as examples of general market performance and no index isdirectly comparable to the past or future performance of the Certificate.
It should not be assumed that the Certificate will invest in any specific securities that comprise any index,nor should it be understood to mean that there is a correlation between the Certificate’s returns and anyindex returns.
Any material provided to you is intended only for discussion purposes and is not intended as an offer orsolicitation with respect to the purchase or sale of any security and should not be relied upon by you inevaluating the merits of investing in any securities.
17Disclaimer