Biologyf5 09 Blood Circulatory System

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    1.2 The Circulatory System

    The circulatory system:-

    (a) Delivers nutrients and oxygen to

    cells(b) Carries waste products away from

    the cells

    (c) Protects the body from infections

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    The Circulatory System has three

    major components:-

    The blood

    The heart

    Blood vessels- arteries, capillariesand veins

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    Blood and Haemolymph

    Blood is the medium of transport in

    humans and animals

    In many invertebrates such as theinsects, the medium of transport is

    called the haemolymph

    Haemolymph is a blood-like nutritive

    fluid which fills the entire body cavity

    (haemocoel) and surrounds all cells

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    The Functions ofBlood

    Transportation, regulation and protection

    Blood transports:-

    (a) Oxygen from the lungs to the cells of the

    whole body, and carbon dioxide from the

    cells to the lungs

    (b) Nutrients, hormones and antibodies

    throughout the body(c) Waste products away from the cells to

    the organs of the excretory system

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    The Functions ofBlood in

    Regulation

    Blood regulates:-

    (a) The pH of body fluids

    (b) The body temperature(c) The water content of cells

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    The Function of Blood in protection

    The blood protects us

    (a) From excessive blood loss in aninjury through the mechanism ofblood clotting. It helps to healwounds

    (b) From diseases and helps to fight

    against infections, for example,white blood cells carry outphagocytosis

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    The Functions of Haemolymph

    Transports water, inorganic salts

    and organic compounds throughout

    the hoemocoel

    Unlike blood, haemolymph does not

    transport respiratory gases

    In insects, respiratory gases are

    transported via the tracheal system

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    The Composition of Human Blood

    Human blood is made up of 55% plasmaand 45% cellular components

    Plasma is the main transport medium in the

    bodyPlasma contains water, ions (sodium,potassium, magnesium, calcium, chlorideand bicarbonate), plasma proteins

    (albumin, fibrinogen and immunoglobulins),hormones and dissolved substances(nutrients and wastes)

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    Cellular Components

    Red blood cells or erythrocytes

    White blood cells (leucocytes)

    Platelets

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    Erythrocytes (red blood cells)

    Shaped like a biconcave disc

    Does not have a nucleus

    Has an elastic membrane which enables it tosqueeze easily into the tiniest blood capillaries

    A single erythrocyte contains about 250 millionmolecules ofhaemoglobin

    Haemoglobin is an oxygen-carrying proteinpigment that gives the erythrocyte its red colour

    Haemoglobin contains a haem group.The haem group contains an iron atom and is siteof oxygen binding

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    Picture shows the red blood cells

    and some leucocytes and

    platelets

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    Drawing shows the types of blood

    cells in the human blood

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    Another drawing that shows the

    types of human blood cells

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    Erythrocyte: Characteristics

    The normal lifespan of an erythrocyte is

    about 120 days, after which it is destroyed

    in the liver and spleen

    Erythrocytes are continuouslymanufactured in the bone marrow of long

    bones, the ribs, the skull and vertebrae

    As erythrocytes mature, they lose their

    nuclei and mitochondria, giving them the

    distinctive biconcave-disc shape

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    Leucocytes

    Colourless and have nuclei and mitochondria

    Irregularin shape

    Make up less than 1% of the volume of blood

    Made by the stem cells in the bone marrowTheir collective function is to fight infections invarious ways

    Most activities of leucocytes take place in theinterstitial fluid outside the blood vessel

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    Leucocytes: Classes

    Classified either as granular or agranular

    Granulocytes:-

    (a) Have granular cytoplasm and lobed nuclei

    (b) Neutrophils- phagocytic granulocytes thatengulf and digest bacteria and dead cells

    (c) Eosinophils- release enzymes to combatinflammation in allergic reactions; also killparasitic worms

    (d) Basophils- involved in combating inflammatoryand allergic reactions, secrete heparin toprevent blood from clotting

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    Types ofLeucocytes:

    Agranulocytes

    Have clear cytoplasm and their

    nuclei are not lobed

    Lymphocytes- produce the immuneresponse against foreign

    substances

    Monocytes- engulf and digest

    bacteria and dead cells

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    Human Blood Vessels

    Three types of human blood vessels:arteries, veins and capillaries

    Walls of arteries and veins consist of

    epithelial tissues surrounded by smoothmuscles and connective tissues

    The thick, muscular and elastic walls of thearteries enable them to withstand the high

    pressure of blood flowing through themThe aorta is the main artery leaving theheart

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    The Pulmonary Artery and Vein

    The pulmonary artery is the only

    artery that carries deoxygenated

    blood from heart to the lungs

    The pulmonary vein is the only vein

    that carries oxygenated blood from

    the lungs to the heart

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    Arterioles and capillaries

    Arterioles are smaller arteries that branchinto a network of capillaries which reachinto the tissues

    Capillaries are tiny, thin-walled bloodvessels

    Respiratory gases, nutrients, wasteproducts and hormones are exchanged by

    diffusion between the blood and theinterstitial fluid surrounding the cells acrossthe thin walls of the capillaries

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    Revision Exercise 1 (10 mins)

    Explain the importance of thehuman blood circulatory system.

    There are different compositions in

    the human blood. Explain thefunction of the cellular component

    of the human blood.

    The Human Immunodeficiency Virus

    (HIV) attacks the human body

    defense system. An HIV patient lacks

    the T-cells, which is a type of

    lymphocyte. Explain the effects of

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    Revision Exercise 2 (10 mins)

    Arteries have small lumen and a verythick, muscularized wall. Explain the

    importance of this feature in the

    blood circulatory system.A deep-vein thrombosis (DVT)

    which is also known as the long-flight

    syndrome occurs when a person sits

    or stands for a long period. Explain

    how this condition occurs by

    referring to the human blood vessels

    involved.