Biology 213 Syllabus Microbiology · PDF fileFoundations in Microbiology, Talaro & Chess, 10th...

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1 Updated FA2017 Biology Program STEM Institute STEM Biology 213 Syllabus Microbiology B R O O K D A L E C O M M U N I T Y C O L L E G E

Transcript of Biology 213 Syllabus Microbiology · PDF fileFoundations in Microbiology, Talaro & Chess, 10th...

Page 1: Biology 213 Syllabus Microbiology · PDF fileFoundations in Microbiology, Talaro & Chess, 10th edition, 2018 Laboratory Manual: Microbiology Fundamentals, ... Unit Six: Microbe-Human

1 Updated FA2017 Biology Program

STEM Institute

STEM

Biology 213 Syllabus

Microbiology

B R O O K D A L E C O M M U N I T Y C O L L E G E

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REQUIRED MATERIALS: Foundations in Microbiology, Talaro & Chess, 1 0

th edition, 2018

Laboratory Manual: Microbiology Fundamentals, Obenauf and Finazzo, 2013

Packages available in bookstore:

Textbook + Lab Manual + Connect : ISBN – 13 9781307013238

Lab Manual + Connect : ISBN – 13 9781307013221

Lab Manual : ISBN - 9781307013245

ADDITIONAL TIME REQUIREMENT: For information on Brookdale’s policy on credit hour requirements and outside class student work refer to Academic Credit Hour Policy.

COURSE LEARNING OUTCOMES: Demonstrate knowledge of pathogenic microorganisms.

Apply the scientific method in a laboratory research project in the isolation and identification of unknown microorganisms.

Demonstrate knowledge of how chemotherapy, immunology, and serology are used to combat pathogens.

(Mathematical/Scientific Reasoning/Information Literacy)

COURSE CONTENT: Unit One: Introduction to Microbiology and Taxonomy

Unit Two: General Characteristics and Representative Examples of Prokaryotic & Eukaryotic Organisms, & Viruses

Unit Three: Microbial Metabolism, Ecology, & Growth

Unit Four: Microbial Genetics

Unit Five: Antimicrobial Actions

Unit Six: Microbe-Human Interactions

Unit Seven: Survey of Microorganisms of Medical Importance

GRADING STANDARD: Active and frequent participation in each chapter is required for optimum performance in this course. Students will be assessed based

on their participation and performance in class and laboratory:

Lecture exams and quizzes: 75%

Laboratory assignments, quizzes, technique evaluation, practical exams: 25%

CODE: BIOL 213 TITLE:

Institute: STEM DEPARTMENT: Biology

COURSE DESCRIPTION: The biology of pathogenic microorganisms will be stressed, emphasizing their microscopic and molecular aspects. Students will describe, in detail, the relationship existing between the host-parasite complex during the diseased state. They

will also become acquainted with those characteristics which endow certain microbes with a pathogenic nature. Students will be able

to list and characterize various pathogenic bacteria, viruses, and eukaryotic parasites (including fungi, algae, protozoa, and helminths).

Isolation and identification techniques in microbiology will be mastered by the student in the laboratory. The role of chemotherapy,

immunology and serology used to combat pathogens will be examined thoroughly. Finally, the homeostatic defense mechanism of the

body, especially those against invading microorganisms, will be discussed in great detail.

PREREQUISITES: A grade of “C” or higher in BIOL 102 or BIOL 112.

COREQUISITES: None

4 LECTURE HOURS: 3 LAB HOURS: 3

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A student must have an average of 65% or higher for the classroom component and an average of 65% or higher for the

laboratory component of the course in order to earn a passing grade for the course. Upon completion of the course, grades will be assigned as follows:

A = 92 – 100%

A- = 89 - 91% C+ = 76 – 78%

B+ = 86 – 88% C = 70 – 75%

B = 82 – 85% D = 65 – 69%

B- = 79 - 81% F = <65%

Unit examination results will be reported as the grade assigned by the faculty calculated to the first

decimal place. These grades will be weighed according to course grading policy. In calculating the course

grade, 0.5 will round up to the next numerical grade and 0.4 will round down to the next lower numerical

grade.

A grade of C or higher is required in all prerequisite courses. Career studies courses must have a grade of C or higher to count toward

the Mathematics / Science Program – Biology Option.

Students are permitted to withdraw from the course without penalty until approximately 80% of the semester is complete. Please see

term schedule for the exact deadline.

At the end of the semester, application for an Incomplete may be made if a student with proper documentation needs to complete no

more than one lecture exam and/or one laboratory practical. The granting of an Incomplete is at the discretion of the instructor.

(Please see Instructor’s syllabus for additional Grading Policies.)

DEPARTMENT POLICIES: Attendance during class and laboratory sessions is strongly recommended for optimum performance in biology courses. Lecture exams will be given in class.

Laboratory practicals will be given during laboratory sessions, in accordance with schedules provided by the learning assistants.

Exams and practicals must be taken at the times designated by the instructor or learning assistant. A student who misses a lecture

exam or laboratory practical must provide prior notification and proper documentation in order to take the exam or laboratory

practical. The acceptance of said prior notification and proper documentation will be determined by the instructor.

Documentation must be provided within one week of the student’s return to the classroom for a make-up exam or laboratory practical

to be scheduled. A student who is unable to provide proper documentation for a missed exam or laboratory practical will be given a

grade of zero for that exercise. Students may not re-take exams or laboratory practicals on which they perform poorly.

Requirements for the completion of laboratory are listed in the laboratory responsibility sheets for individual courses. Requirements

for course completion are listed in individual instructor syllabi.

COLLEGE POLICIES:

For information regarding:

Brookdale’s Academic Integrity Code

Student Conduct Code

Student Grade Appeal Process

Please refer to the STUDENT HANDBOOK AND BCC CATALOG.

NOTIFICATION FOR STUDENTS WITH DISABILITIES: Brookdale Community College offers reasonable accommodations and/or services to persons with disabilities. Students with

disabilities who wish to self-identify, must contact the Disabilities Services Office at 732-224-2730 or 732-842-4211 (TTY), provide

appropriate documentation of the disability, and request specific accommodations or services. If a student qualifies, reasonable

accommodations and/or services, which are appropriate for the college level and are recommended in the documentation, can be

approved.

ADDITIONAL SUPPORT/LABS: BIOL 213 course and laboratory resources are available in CANVAS, Brookdale’s Learning Management System, available via the

Brookdale website: www.brookdalecc.edu

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Independent Study Laboratory (Open Lab) – MAS 041 – is available to students enrolled in this biology course. Students use this

lab to review lab materials, and to get help with course materials from learning assistants that staff the lab.

Brookdale Biology Department course and program information is available on the Biology Department website:

http://sites.brookdalecc.edu/home/stem-institute/biology/

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BIOL 213 Microbiology # 1 of 7 Units 4 Course No. Title Credits

Name of Unit: INTRODUCTION TO MICROBIOLOGY AND TAXONOMY

Textbook: Foundations in Microbiology, 10th edition, Chapter 1

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Define microbiology. page 3

2. Compare and contrast microorganisms: viruses, pages 3-7 bacteria, protozoa, algae, fungi and helminths

3. Describe units of measurement used for microorganisms. page 8

4. Identify various branches in the field of microbiology. pages 2-5, 10

5. Describe the significance of microorganisms: pages 9-11

-medically, environmentally and commercially/economically

6. Recognize the contributions made by scientists to the field of of microbiology, to include: pages 13-18

Robert Hooke Paul Ehrlich Anton van Leeuwenhoek Alexander Fleming Francesco Redi Ernst Chain & Howard Florey Louis Pasteur Selman Waksman Robert Koch Rebecca Lancefield Joseph Lister Avery, MacLeod & McCarty Edward Jenner James Watson & Frances Crick Hans Christian Gram Nathans, Smith & Arber Elie Metchnikoff

7. Describe the contributions of Carolus Linnaeus (the pages 19, 23, 24

“Father of Taxonomy”), Robert Whittaker, and Carl Woese to the field of taxonomy.

8. Describe the current system of classification in biology: pages 19, 22-24 3 domains 5 kingdoms further categories

9. Describe the classification of prokaryotes and viruses, to pages 110-113, 170-172

include the criteria used to classify microorganisms.

10. Describe classification systems of prokaryotic domains in

Bergey’s Manual of Systematic Bacteriology 2nd ed. pages 110-113

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11. Describe the classification of eukaryotic organisms to include criteria used for each group. pages 143-145, 147-150, 154-155

12. Correctly use the universal system of scientific naming of pages 19-21

organisms - binomial nomenclature

13. Demonstrate the ability to use dichotomous keys in the identification of microorganisms.

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BIOL 213 Microbiology # 2 of 7 Units 4 Course No. Title Credits

Name of Unit: GENERAL CHARACTERISTICS AND REPRESENTATIVE EXAMPLES OF PROKARYOTIC AND EUKARYOTIC ORGANISMS, AND VIRUSES

Textbook: Foundations in Microbiology, 10th edition, Chapters 4, 5, & 6

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Compare properties and cell structures in prokaryotes pages 91, 136, Table 5.4

and eukaryotes.

2. Describe sizes, shapes, and arrangement of prokaryotes. pages 107-109

3. Describe the following prokaryotic cell structures and their pages 92-105 related functions:

a. Structures external to cell wall

1. Flagella pages 93-94 2. Axial Filaments (periplasmic flagella) page 95 3. Pili and Fimbriae pages 95-96 4. Glycocalyx page 96-98

a. capsule b. slime layer

b. Cell wall pages 72-73, 99-102 1. Functions 2. Composition & characteristics 3. Gram stain 4. Negative Stain

c. Structures internal to cell wall pages 102-106 1. Plasma membrane 2. Cytoplasm 3. Nucleoid – chromosome 4. Plasmid 5. Ribosomes 6. Inclusions 7. Endospores

4. Describe biofilms and explain their significance pages 89, 96-98

5. Survey prokaryotic groups with unusual characteristics pages 115-120

6. Describe the history of eukaryotic cells including the

endosymbiotic hypothesis/theory pages 126-127

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7. Review eukaryotic cell structures and their functions. pages 127-136 -external -internal

8. Describe the basic characteristics of the Kingdom Fungi

including general types of cells and organisms, structure, and nutrition; differentiate between yeasts and molds, types of fungal spores; importance in medicine, nature and industry. pages 138-146

9. Discuss general characteristics of algae, and importance . pages 146-154

10. Discuss general characteristics, basic morphology of major

groups of parasitic helminths, life cycles, reproduction pages 154-155

11. Describe viral origin, history, characteristics, structure, morphology, and importance. pages 160-171

12. Describe viral multiplication including

-multiplication of animal viruses (DNA and RNA); damage to host cell pages 172-176

-bacteriophage multiplication, lysogeny pages 177-179 13. Discuss cultivation, detection, and treatment of viruses. pages 179-182

14. Describe nonviral infectious particles including prions and viroids. pages 183-184

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BIOL 213 Microbiology #3 of 7 Units 4 Course No. Title Credits

Name of Unit: MICROBIAL METABOLISM, ECOLOGY, AND GROWTH

Textbook: Foundations in Microbiology, 10th edition, Chapters 2, 7, & 8

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Review composition, properties, and functions of macromolecules. pages 41-54

2. Describe major categories of nutritional types among organisms. pages 190-196

3. Define requirements for microbial growth including pages 189-206; 39-41 -Micronutrients, macronutrients, essential nutrients -Physical and Chemical Requirements

Carbon, oxygen, water, phosphate, nitrogen, sulfur Temperature Osmotic Pressure pH

4. Define bacterial growth. pages 211-213

5. Define generation time or doubling time in prokaryotes page 212

6. Name and describe the stages in the bacterial growth curve. pages 214-216

7. Discuss direct and indirect methods of analyzing bacterial population

growth. pages 214-217

8. Discuss the range of ecological associations among microorganisms and interrelationships between microbes and humans. pages 206-210

9. Describe the development and significance of biofilm association. pages 210-211

10. Define metabolism. Describe the following: pages 224-236

-catabolism and anabolism -role of ATP -metabolic pathways -enzymes and enzyme action -factors influencing enzymatic activity -oxidation-reduction reactions -generation of ATP

11. Demonstrate an understanding of the following metabolic pathways pages 236-251; Appendix A

In microorganisms:

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Carbohydrate catabolism Glycolysis Aerobic Respiration

Bridge reaction (Transition or Preparatory step) Krebs Cycle Electron Transport Chain

Anaerobic Respiration Fermentation reactions

Lipid and protein catabolism Anabolic pathways

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BIOL 213 Microbiology # 4 of 7 Units 4 Course No. Title Credits

Name of Unit: MICROBIAL GENETICS

Textbook: Foundations in Microbiology, 10th edition, Chapters 2, 9, & 10

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Describe the structure of the nucleic acids – DNA & RNA pages 52-55, 264, 266

2. Describe the relationships among DNA, gene, genome, pages 262-263

chromosome, genotype, phenotype.

3. Compare the genome of prokaryotes to that of eukaryotes. page 263

4. Describe the process of DNA replication in prokaryotes. pages 265-269

5. Describe the process of RNA replication in prokaryotes. pages 270-274

6. Describe the process of protein synthesis in prokaryotes. pages 275-278

7. Explain the operon model of gene expression. Describe pages 278--281 regulation of gene expression in bacteria by induction and repression.

8. Define mutation. Describe types of mutations and pages 283-286

categories of mutagens.

9. Compare the mechanisms of genetic recombination in bacteria. pages 287-292 Differentiate between horizontal and vertical gene transfer.

10. Describe the functions of vectors (plasmids and phages) pages 102, 257, 285-286, 303-304, 373

and transposons.

11. Compare replication strategies in DNA and RNA viruses. pages 292-293

12. Describe methods and applications of genetic engineering. pages 300-308, 309-312, 313, 317-319

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# 5 of 7 Units BIOL 213 Course No.

Microbiology Title

4 Credits

Name of Unit: ANTIMICROBIAL ACTIONS

12

Textbook: Foundations in Microbiology, 10th edition, Chapters 11 & 12

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Define and differentiate among the major terms for microbial pages 329-332

control including

Sterilization

Disinfection

Antisepsis

Sanitation

Degerming

2. Identify factors that influence effectiveness of antimicrobial agents or methods. pages 332-334

3. Identify the targets of antimicrobial control agents. pages 365-369

4. Describe the actions and effects of physical and chemical

agents or methods used to control microbial growth. pages 334-335

5. Describe antimicrobial drugs and distinguish between antibiotics, synthetics, and semisynthetics pages 364-365, Table 12.3

6. Identify the primary sources if antibiotics. pages 362-364

7. Identify characteristics of ideal antimicrobial drugs. page 362

8. Describe the mechanisms of action of antimicrobial drugs. pages 365-369, Table 12.4

9. Identify commonly used antibacterial drugs according to mode of action. page 365-366 Figure 12.2

10. Identify the modes of action and representative examples of

major antimicrobial groups including: pages 379-388

Antibacterial drugs

Antifungal drugs

Antiparasitic drugs

Antiviral drugs

11. Describe the mechanisms of drug resistance pages 381-385

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12. Identify side effects of antimicrobial drug use in humans. pages 375-378

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13. Discuss the effects of combining antimicrobial drugs. page 364 14. Describe tests for microbial susceptibility to antimicrobial

drugs. pages 385-391

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# 6 of 7 Units BIOL 213 Course No.

Microbiology Title

4 Credits

Name of Unit: MICROBE-HUMAN INTERACTIONS

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Textbook: Foundations in Microbiology, 10th edition, Chapter 13

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Define the terms associated with infectious diseases. page 399

2. Define normal microbiota. Distinguish between resident and transient microbiota. Identify sites that harbor normal microbiota and those that are microbe-free. pages 399-407

3. Discuss the major factors in the development of an infection including entry, adhesion, multiplication, effects. Compare endotoxins and exotoxins. pages 409-415

4. Describe the clinical stages of disease. pages 417-418

5. Discuss the patterns of infection and distinguish between

localized and systemic, focal and mixed, primary and secondary, endogenous and exogenous infections. pages 417-418

6. Use correct terminology to explain the manifestations (signs

and symptoms) of infections and inflammation. pages 419-420

7. Describe the transmission of disease by identifying reservoirs of infection, distinguishing between types of vectors, and types of carriers. Define zoonoses. pages 421-424

8. Describe the transmission of disease. Distinguish between

communicable, noncommunicable, and contagious diseases. pages 424-426

9. Define nosocomial infections and explain their significance. pages 429-431

10. Define epidemiology and explain the major methods of tracking infections and diseases in a population. pages 426-431

11. Differentiate among the patterns of disease outbreaks according to frequency, number, location, and duration. pages 426-428

12. Demonstrate a thorough understanding of Koch’s Postulates. page 18

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# 7 of 7 Units BIOL 213 Course No.

Microbiology Title

4 Credits

Name of Unit: SURVEY OF MICROORGANISMS OF MEDICAL IMPORTANCE

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Textbook: Foundations in Microbiology, 10th edition, Chapters 17, 18, 19, 20, 21, 22, 23, 24, & 25

Method of Evaluation: Lecture Exams and Quizzes, Laboratory Practicals, Quizzes, and Project

Objectives Recommended Learning Experiences

The student will be able to: Class Discussion Textbook Readings:

1. Summarize common procedures used for identifying pathogens and diagnosing infections. pages 535-552

2. Describe each of the following bacteria to include:

general characteristics: structure, arrangement, staining properties

metabolic and pathogenic properties

diseases caused in humans and locations in body

A. Gram-Positive cocci 1.) Staphylococcus pages 557-564 2.) Streptococcus pages 565-570, 571-574 3.) Enterococcus page 570

B. Gram-Negative cocci

1.) Neisseria pages 575-582 2.) Moraxella page 582

C. Gram-Positive endospore forming bacilli

1.) Bacillus pages 588-592 2.) Clostridium pages 592-598

D. Gram-Positive Regular Non-spore-forming bacilli

1.) Listeria pages 587, 599-600

E. Gram-Positive Irregular Non-spore-forming bacilli 1.) Corynebacterium pages 601-602 2.) Propionibacterium page 602

F. Mycobacterium: Acid-Fast Bacilli

1.) M. tuberculosis pages 603-608 2.) M. leprae pages 608-610

G. Actinomycetes: Filamentous bacilli 1.) Actinomyces page 612 2.) Nocardia pages 612-613

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H. Gram-Negative Aerobic Bacilli

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1.) Pseudomonas pages 619-622 2.) Burkholderia, Acinetobacter pages 260, 294, 582, 622-623 3.) Brucella page 623 4.) Francisella page 624 5.) Bordetella pages 618-619, 624-625 6.) Legionella pages 626-629

I. Gram-Negative Facultative Anaerobic Bacilli

- Family Enterobacteriaceae pages 628-634 1.) Coliform Enteric Organisms: E. coli pages 631-634

Serratia Klebsiella Enterobacter Citrobacter

2.) Noncoliform Enteric Organisms: Proteus page 634

Providencia Morganella

3.) True Enteric Pathogens: Salmonella pages 634-639 Shigella

Yersinia enterocolitica

4.) Nonenteric Organism: Yesinia pestis pages 639-641

-Family Pasteurellaceae 1.) Pasteurella page 641 2.) Haemophilus pages 642-643

J. The Spirochetes pages 649-658

1.) Treponema pages 649-654 2.) Leptospira pages 654-655 3.) Borrelia pages 655-658

K. Curviform Gram-Negative Bacteria pages 658-662

1.) Vibrio pages 658-661 2.) Campylobacter page 661 3.) Helicobacter pages 661-662

L. Order Rickettsiales pages 663-668

1.) Rickettsia pages 663-667 2.) Ehrlichia pages 667-668 3.) Anaplasma page 667-668 4.) Coxiella page 667-668 5.) Bartonella pages 667-668

M. Family Chlamydiaciae pages 668-671

1.) Chlamydia pages 668-670 2.) Chlamydophila pages 670-671

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N. Cell-Wall-Deficient Bacteria 1.) Mycoplasma pages 671-672

3. Describe Fungi of Medical Importance to include: pages 682-704

general characteristics

degree of pathogenicity

nature of infection (primary or secondary; true or opportunistic)and infecting form

habitat and geographic location

metabolic and pathogenic properties

organization of fungal diseases (mycoses)

characteristics of common antifungal drugs

A. Systemic Fungal Pathogens 1.) Histoplasma pages 681- 652, 688-690 2.) Coccidioides pages 681- 682, 690-691 3.) Blastomyces pages 681- 682, 692-693

B. Subcutaneous Fungal Pathogens

1.) Sporothrix pages 681-682. 694

C. Cutaneous Fungal Pathogens (Dermatophytes) 1.) Tricophyton pages 681-682, 696-698 2.) Microsporum pages 681-682, 696-698 3.) Epidermophyton pages 681-682, 696-698

D. Opportunistic Fungal Pathogens 1.) Candida pages 681-682, 699-700 2.) Cryptococcus pages 6 8 1 - 6 8 2 , 700-702 3.) Pneumocystis pages 681-682, 702 4.) Aspergillus pages 681-682, 702-703

4. Define terms associated with parasitology page 712

5. Describe Parasites of Medical Importance to include pages 711-728

general characteristics of each group of parasitic pathogens

portals of entry, habitat, geographic location

diseases caused in humans and location in the body

antiparasitic drugs of choice

A. Protozoan Pathogens 1.)

Amoeboid Protozoa a. Entamoeba pages 712-713, 712-714 b. Naegleria pages 712-713, 715-716

2.) Ciliate Protozoan

a. Balantidium coli pages 712-713, 715

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3.) Flagellate (Mastigophoran) Protozoa a. Trichomonas pages 711-713, 716 b. Giardia pages 711-713, 717 c. Trypanosoma pages 711-713, 718-720 d. Leishmania pages 711-713, 720-721

4.) Apicomplexan Protozoa a. Plasmodium pages 711-713, 722-725 b. Toxoplasma pages 711-713, 725-727 c. Cryptosporidium pages 711-713, 727 d. Cyclospora pages 711-713, 727-728 e. Babesia pages 711-713, 728

B. Helminthic Pathogens pages 728-737

1.) Nematodes (Roundworms) pages 729, 714, 717 a. Ascaris pages 729, 732-733 b. Trichuris trichiura pages 729, 733 b. Enterobius pages 729 718 c. Trichinella pages 729, 735-736 d. Wuchereria pages 729, 736-737 e. Onchocerca pages 729, 737 f. Loa loa pages 729, 737 g. Necator americanus pages 729, 733 h. Dracunculus pages 729, 737

2.) Trematodes or Flukes (Flatworms) pages 729, 737-739

a. Schistosoma pages 729,730, 738 b. Fasciola pages 729, 730, 738, 739 c. Paragonimus pages 729, 739

3.) Cestodes or Tapeworms (Flatworms) pages 729,739-740

a. Taenia solium, T. saginata pages 729, 739-740 b. Diphyllobothrium page 729, 740 c. Echinococcus

6. Differentiate among the Arthropod vectors of infectious

disease pages 741-742

7. Describe DNA and RNA Viruses that infect humans. Discuss

general characteristics, identification, diagnosis, classification, effects of infection on host cells

diseases and location in the body pages 749-809

A. Enveloped Double-stranded DNA Viruses pages 750-766

1.) Poxviruses (Poxviridae) pages 171, 750-754 a. Variola, Vaccinia pages 171, 750-754

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2.) Herpesviruses (Herpesviridae) pages 171, 750, 755-763 a. Herpes simplex virus (HSV-1 and HSV-2) pages 171, 750, 756-757 b. Varicella-Zoster Virus (VZV) pages 171, 750, 758-759, 770 c. Epstein-Barr Virus (EBV) pages 523, 524, 750,754, 760-763 d. Cytomegalovirus (CMV) pages 171, 750, 754, 760 e. Herpesviruses 6, 7, 8 pages 750, 754

3.) Hepadnaviruses (Hepadnaviridae) pages 171, 750, 763-766

a. Hepatitis B Virus (HBV) pages 171, 750, 764-766

B. Nonenveloped Double-stranded DNA Viruses pages 751-753

1.) Papillomaviruses (Papillomaviridae) pages 171, 750, 767-769 a. Human Papillomavirus (HPV) pages 171, 750, 767-769

C. Nonenveloped Single-stranded DNA Viruses page 769

1.) Parvoviruses (Parvoviridae) pages 171, 750, 769

a. Parvovirus (Erythrovirus) 5th Disease pages 171, 750, 769 D. Enveloped Segmented Single-stranded RNA Viruses

1.) Orthomyxoviruses (Orthomyxoviridae) (ss-) pages 171, 775-776, 775-780 a. Influenza virus A, B, C pages 171, 775-776, 775-781

2.) Bunyaviruses (Bunyaviridae) (ss-) pages 171, 775-776, 781, 789

a. Hantavirus pages 171, 775-776, 781

E. Enveloped Nonsegmented Single-stranded RNA Viruses

1.) Paramyxoviruses (Paramyxoviridae) (ss-) pages 171, 775-776, 767 a. Paramyxovirus (parainfluenza virus types 1-5 and

mumps virus) pages 171, 775-776, 781-782 b. Morbillivirus (measles/rubeola virus) (ss-) pages 171, 775-776, 783-784 c. Pneumovirus (respiratory syncytial virus (RSV) (ss-) pages 171, 775-776, 785

2.) Rhabdoviruses (Rhabdoviridae) (ss-) pages 172, 775-776, 785-787

a. Lyssavirus (Rabies virus) pages 172, 775-776, 785-787

3.) Filoviruses (Filoviridae) (ss-) page 171, 397, 779 a. Ebola virus pages 171, 397, 427,432, 776,779 b. Marburg virus pages 171, 775-776, 779

4.) Coronaviruses (Coronaviridae) (ss+) pages 172, 775-776, 787

a. Coronavirus /Severe Acute Respiratory Syndrome Virus (SARS) (ss+) pages 172, 775-776, 787

5.) Togaviruses (Togaviridae) (ss+) pages 171, 775-776, 788

a. Rubivirus (Rubella/ German Measles)) pages 171, 775-776, 788

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b. Alphavirus (Yellow Fever, Eastern & Western Equine Encephalitis, Chikungunya virus, Zika) pages 171, 775-776, 789, 791

6.) Flaviviruses (Flaviviridae) (ss+)

a. Flavivirus (Dengue Fever virus, West Nile Fever virus, Hepatitis C virus (HCV)) pages 171, 788-789

7.) Picornaviruses (Picornaviridae) (ss+) pages 171, 802

a. Enterovirus (Poliovirus, Coxsackie virus) pages 171, 802-805 b. Hepatovirus (Hepatitis A virus (HAV)) pages 171, 763, 802-805 c. Rhinovirus (Common Cold virus) pages 171, 202, 776, 802, 806

8.) Caliciviruses (Caliciviridae) (ss+)

a. Calicivirus / Norovirus (Norwalk agent) pages 171, 775-776, 806

F. Double-stranded Nonenveloped RNA viruses

1.) Reoviruses (Reoviridae ) pages 171, 806-808 a. Rotavirus pages 172, 775-776, 806-807

G. Double-stranded Enveloped RNA viruses produce DNA

using Reverse transcriptase pages 792-801

1.) Retroviruses (Retroviridae) pages 172, 775-776, 288, 777-786

a. Lentivirus (HIV) pages 172, 775-776, 792-800 b. Oncornavirus (Human T-Cell Lymphotropic virus I)

(HTLV-1) (Leukemia) pages 172, 775-776, 792-801

8. Define Arbovirus; describe the pathology and mode of Transmission of arboviruses pages 789

9. Explain the pathogenesis, transmission, and epidemiology of prion diseases pages 183-184, 329-330, 354, 776, 807-808