Introduction to Bioinformatics: Lecture III Genome Assembly and String Matching
Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.
-
date post
18-Dec-2015 -
Category
Documents
-
view
217 -
download
1
Transcript of Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.
![Page 1: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/1.jpg)
Bioinformatics+
The Human Genome Project
Teacher ConferenceFriday October 19th, 2007
![Page 2: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/2.jpg)
February 2001: Completion of the Draft Human GenomeFebruary 2001: Completion of the Draft Human Genome
Public HGPPublic HGP Celera GenomicsCelera Genomics
April 14, 2003:
April 14, 2003:
The Human Genome is completed – again!
The Human Genome is completed – again!
October 2004 - present:
October 2004 - present:
The Human Genome is now really finished!
The Human Genome is now really finished!
The Human Genome Project
![Page 3: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/3.jpg)
![Page 4: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/4.jpg)
To carry the sequence of my genome in my pocket, I need:
• (a) supercomputer• (b) my laptop (brand new)• (c) my home computer (Oops, it’s old)• (d) DVD• (e) CD• (e) zip disk• (f) floppy disk
If compressed, the 3GB human genomewill also fit on a single CD
![Page 5: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/5.jpg)
The Human Genome…By the Numbers
75-100 trillion…Cells in the human body3.1 billion…Base pairs in each cell2.4 million…Base pairs in the largest human gene28,000-35,000…Genes in the human genome46…Chromosomes in each cell
![Page 6: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/6.jpg)
Technology
![Page 7: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/7.jpg)
What is Bioinformatics?
![Page 8: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/8.jpg)
![Page 9: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/9.jpg)
maps.google.ca
![Page 10: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/10.jpg)
Let’s Look at the Human Genome...
![Page 11: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/11.jpg)
Websites visited during thisBioinformatics 101 Workshop
• Google www.google.ca• Google Maps http://maps.google.ca• UCSC Human Genome Browser Gateway
– http://genome.ucsc.edu/cgi-bin/hgGateway
(hint: use google to look up “Genome Browser”)
![Page 12: Bioinformatics + The Human Genome Project Teacher Conference Friday October 19 th, 2007.](https://reader030.fdocuments.net/reader030/viewer/2022032800/56649d235503460f949f9f38/html5/thumbnails/12.jpg)
Image Credits• DNA with Features
– Image credit: Genome Management Information System, Oak Ridge National Laboratory; Available from: http://genomics.energy.gov/gallery/
• Human Genome Project - Science cover– Image credit: Ann Elliott Cutting; Available from: http://www.sciencemag.org/content/vol291/issue5507/cover.dtl
• Human Genome Project - Nature cover– Image available from: http://www.nature.com/nature/journal/v409/n6822/index.html
• What is Bioinformatics?– Image credit: Jiang Long; Available from: http://www.scq.ubc.ca/what-is-bioinformatics
• Science@NASA universe logo– Image available from: http://science.hq.nasa.gov/universe/images/universe_09.jpg
• 1960 Film Projector– Image available from: http://en.wikipedia.org/wiki/Slide_projector
• iPod nano– Image available from: http://www.apple.com/ipodnano/
• Downtown Bus Route map– Available from: http://translink.bc.ca/
• MSL and nearby coffee shops at UBC map– Available from: http://maps.google.ca/
• A view of the Leptin Precusor Gene in the UCSC Genome Browser– Available from: http://genome.ucsc.edu/cgi-bin/hgTracks?
hgsid=98731626&hgt.out1=1.5x&position=chr7%3A127669698-127691768