RRX Pharma-Bioinformatics Future Challenges in Bioinformatics.
bioinformatics presentation
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Transcript of bioinformatics presentation
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Adnan Amer Saadeddin
20610462
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Whats bioinformatics
The components of bioinformatics
Biological data
Molecular Biology and Computational Abstractions
Bioinformatics App. & Comp.
Bioinformatics challenges
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Bio informatics
Bioinformatics is the application which combine thedisciplines of mathematics like statics and computerscience e.g Database, data mining etc tounderstand and organize the information associatedwith the biology in terms of molecules the same insize and large in numbers, on large-scale
In simple its using the computer systems to answer biologicalquestions
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We can think about thefunctionality of theMolecular biology asits a black box that wedont know whats
inside it and we wantto understand how touse it. Black Box
input
output
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1-Biological Data
2-Computers3-Algorithms
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DNA RNA P
r tei
Phe type acti
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DNA RNA Protein Phenotype action
We deal withthe DNA as
an inputstring whichhas its ownlanguage.
The RNA isthe output of
from th
eprocess of theDNA but wedeal with it asits a input forthe nextprocess
The sameconcept
with theprotein
Theaction is
the finaloutputfor theprocess
Informationtransfer
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Information is measured in bits
1 bit := choice between two equally possibleoutcomes
DNA : 2 bits per base
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Applications
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Applications
Experiment Computation
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Data archival and retrieval
Databases, experimental automation
Cross-species comparisons
Experiments in yeast are easier than in mice wherethey are easier than in humans
Drug design
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Biological Redundancy and multiplicity
Different Sequences with similar structures
Organisms with similar genes
Multiple functions of single genes
Grouping of genes in pathways
Sequence redundancy in genomes
Signal versus Noise
Lack of Data
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Any Questions
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