Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics...
Transcript of Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics...
![Page 1: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/1.jpg)
1
![Page 2: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/2.jpg)
2
![Page 3: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/3.jpg)
3
![Page 4: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/4.jpg)
4
![Page 5: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/5.jpg)
5
![Page 6: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/6.jpg)
6
![Page 7: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/7.jpg)
7
![Page 8: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/8.jpg)
8
Large Animal Clinical Nutrition
Assoc. Prof. Dr. Theera RukkwamsukDept. Large Animal and Wildlife Clinical Science
![Page 9: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/9.jpg)
9
Course description
Basic principles of clinical nutrition in large animals. Nutrient requirements and nutritional management in relation to health, reproduction, and production of cattle, goats, sheep and horses.
![Page 10: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/10.jpg)
10
Study evaluation
Self-study 20%Examination
Midterm 30%Final 30%
Class attendance 20%
![Page 11: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/11.jpg)
11
Topics
Basic concepts and ration formulationProtein nutrition and nonprotein nitrogenMajor minerals and trace mineralsVitamins and water requirementsControl of feed intakeEffects of diseases on nutritional needsFeeding beef cows for optimal productionPasture management and forage relatedhealth problems in beef cattleColostrum and feeding management of dairycalves and nutrition of dairy replacementheifers
![Page 12: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/12.jpg)
12
Topics
Feeding dairy cows for optimal productionNutritional support for sick cattle and calvesFeeding goats for optimal health and productionFeeding sheep for optimal health and productionFeeding horses for optimal growth and productionFeeding sick horses
![Page 13: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/13.jpg)
13
Bioenergetics : basic concepts and ration formulation
Nutrition involves the acquisition and utilization of the chemical substances that are necessary to establish, maintain, and propagate life.
These chemicals are called “nutrient” and include water, carbohydrates, fats, proteins, minerals, and vitamins.
![Page 14: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/14.jpg)
14
Bioenergetics
It is a branch of energetics concerned with energy transformation in living organisms.Energy exists in two states:
Kinetic energy is the energy of motion. This energy is actively engaged in doing work.
Potential energy is stored. The chemical energy in nutrient molecules is an example of potential energy.
![Page 15: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/15.jpg)
15
Systems of energy measurement
Energy is the most critical consideration in animal nutrition.
It is measured as heat expressed as kilocalories (kcal), megacalories (Mcal), or megajoules (MJ).
The energy in foods is stored as potential energy, which is released by chemical reactions.
The kinetic energy released may be used to make muscle contract, to induce glands to secrete, or to supply energy for storage.
![Page 16: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/16.jpg)
16
A number of terms are used to describe energy at various stages of transition from food to animal energy
Gross energy (GE) is obtained from the whole feed.
Fecal energy (FE) is for the fecal matter produced by the digestion of feed. The fecal material contains undigested feed, enteric microbes and their products, and excretions from the gastrointestinal tract.
Combustible gas energy (CGE) is for the nonabsorbable gases (mostly methane) that are produced during digestion. This is most important in ruminants.
![Page 17: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/17.jpg)
17
A number of terms are used to describe energy at various stages of transition from food to animal energy
Digestible energy (DE) equals GE minus FE.Urinary energy (UE) is the energy content of the urine produced by the metabolism of the DE of a specific feed sample.Metabolizable energy (ME) is DE minus (UE plus CGE).Net energy (NE)is ME minus the heat increment (Hi). The heat increment is sometimes called the specific dynamic activity (SDA). The heat increment results from energy lost in the production of digestive secretions and in the absorption, circulation, and metabolic conversion of nutrients into end product.
![Page 18: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/18.jpg)
18
Net energy is divided into two categories.
Net energy for maintenance (NEm)includes the energy required for basal metabolism (Hb) and the energy required for normal activity (Ha).
Net energy for production (NEp) includes energy deposited in growth and fat storage (NEg), energy deposited in the products of gestation (NEr), and energy deposited in milk (NEl), and energy used to perform work (NEw).
![Page 19: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/19.jpg)
19
Energy interconversions
1 Mcal = 1,000 kcal = 4.184 MJ1 kcal = 3.968 British thermal unitsRuminants, horses
1kg TDN = 4.409 Mcal of DE1lb TDN = 2.000 Mcal of DE1kg starch equivalent = 5.082 Mcal of DE1lb starch equivalent = 2.305 Mcal of DE
![Page 20: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/20.jpg)
20
Beef cattle, sheep, goatsME = 0.82 X DE (Underestimates the ME content of high grain rations)
GoatsME = 0.464 X DE
![Page 21: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/21.jpg)
21
Chemical composition of feeds
The energy-containing components of food are mainly proteins, lipids, and carbohydrates
Proteins are composed of amino acids, which consist of a short hydrocarbon chain with an amino (NH2) and a carboxyacid (COOH) group.
![Page 22: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/22.jpg)
22
Lipid is the generic term given to fats, which are solid at room temperature, and oils, which are liquid. Oils have shorter carbon chain lengths and tend to be less saturated but their caloric value is similar to fats.
The main role of fats in animal nutrition is as a concentrated energy source. Fats are useful in situations where it is difficult to meet energy requirements within the constraints of dry matter intake.
![Page 23: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/23.jpg)
23
Carbohydrate (sugar, starches, fiber), carbohydrates are divided into two categories: storage and structural CHO
Storage CHO are compact polysaccharides used as an energy store by plants and animals.
α-linkage that join the sugars can be degraded by mammalian digestive enzymes.
Amylose and amylopectin are the two forms found in plants.
Glycogen is the animal equivalent of plant starch..
![Page 24: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/24.jpg)
24
Structural CHO form dietary fiber, mainly found in the cell wall of plants and tend to be insoluble and provide strength.
In structural CHO, the sugar subunits are joined in chains by β-linkages. These cannot be degraded by mammalian digestive enzymes.Cellulose, a glucose polysaccharide.Hemicellulose, a pentose sugar polymers.Lignin is a polymer of aromatic alcohols.
![Page 25: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/25.jpg)
25
The usefulness of various types of fiber as energy sources depends on the degree of lignification; lignin energy is unavailable, even to herbivours.
Fiber content of feeds is classified according to solubility:
Crude fiber (CF)Neutral detergent fiber (NDF)Acid detergent fiber (ADF)
![Page 26: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/26.jpg)
26
Forage Analysis
Forage analysis showing Crude Fiber (Green) versus Van Soest (Yellow)
Proteins, Ether Extract (Lipids), Ash (Minerals)
Sugars, Starches, Pectins
Hemicellulose
Alkali-SolubleAlkali-Insoluble
CelluloseCrude Fiber
Nitrogen-Free Extract
Cell Contents
Cell WallADF
NDF
![Page 27: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/27.jpg)
27
Energy content of feeds
An old system of estimating the energy content of feeds is the total digestible nutrient (TDN) system. This is the summation of the digestible crude protein, digestible fiber, digestible nitrogen-free extract, and digestible ether extract and is expressed as a percentage of the total amount of feed.
![Page 28: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/28.jpg)
28
Concentrates and roughages
Concentrates contain less than 20% crude fiber.
Roughages contain more than 20% crude fiber.
![Page 29: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/29.jpg)
29
Signs of energy deficiency and toxicity
Energy deficiency causes loss of weight. Animals die when they have lost about 25-30% of normal body weight. Death is thought to be due to protein depletion and loss of respiratory and cardiac muscle function.
Energy restriction delays puberty, and in adults it reduces estrus behavior, ovulation rates and libido. Conception and birth rates fall.
![Page 30: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/30.jpg)
30
Energy excess results in obesity. This may exacerbate chronic lameness and reduces fitness for work. There is reduced reproductive efficiency in both males and females, and dystocia is more likely. Obesity predisposes to ketosis and fatty liver in heavily pregnant sheep and recently calved cattle.
![Page 31: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/31.jpg)
31
Maintenance energy
Basal energy requirement is measured with the animal at rest. It represents the amount of energy used to maintain normal cellular function. Energy requirements for maintenance are about 25-100% higher depending on energy expenditure for movement in the natural environment. Maintenance requirements are even higher if the environment is adverse, for example, because of heat or cold stress.
![Page 32: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/32.jpg)
32
Factors affecting Maintenance energy
Cold and heat stressSeasonGrowth patternForaging
![Page 33: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/33.jpg)
33
Feed-conversion ratio
The feed conversion ratio is the ratio of feed ingested (in kg or Mcal) to liveweight gain. Low ratios of feed fed per unit of gain indicate efficient production. Feed conversion efficiency and feed conversion rates decline with age.
![Page 34: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/34.jpg)
34
Dry matter intake
Dry matter intake is controlled by the animal’s requirement for energy intake and the physical capacity of the gut.When a high-quality diet is fed and requirements are low, food intake is regulated in accordance with requirements.Gastrointestinal fill is the major limiting factor when requirements are high and ration nutrient density is low.
![Page 35: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/35.jpg)
35
Ration formulation
Nutritional advice frequently involves recommendations on the comparative value of different types of feed and the evaluation and formulation of rations for animals.
![Page 36: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/36.jpg)
36
Nutritional goals and sources of information
The first step in diet formulation is to obtain a reliable sources of nutrient requirements for the target animal. For example, the National Research Council (NRC) of the USA, is generally regarded as the authoritative source. Other sources may include extension publications and the results of university research. In some situations, this information may provide useful modifications to published requirements based on “local conditions”.
![Page 37: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/37.jpg)
37
In addition to reliable animal nutrient requirement information, it is essential that accurate feed nutrient values be available for the diet formulation process.
Not only is content required for an increasing number of nutrient fractions, but also descriptive utilization data such as the rate of digestion.
![Page 38: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/38.jpg)
38
Feed formulas and conversions
There are several basic types of data manipulation used in formulating a giving ration:
Amounts of DM to amounts as fed.10 lb of DM required and feed is 30% DM: 10 lb of DM/0.30 ld DM per lb as fed = 33.3 lb as fed.
Amounts as fed to amounts of DM50 lb of corn silage as fed and DM content is 35%: 50 X 0.35 = 17.5 lb DM
![Page 39: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/39.jpg)
39
Feedstuff % of ration DM
DM of feed As fed Total as fed
% As fed
Corn silage
60 0.35 171.4 225.4 76.1
High moisture shelled corn
30 0.70 42.9 225.4 19.0
Supplement
10 0.90 11.1 225.4 4.9
Totals 100 225.4 100.00
![Page 40: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/40.jpg)
40
Feedstuff % As fed DM of feed DM Total number of parts
% Ration DM
Corn silage
76.1 0.35 26.64 44.35 60.1
High moisture shelled corn
19.0 0.70 13.30 44.35 30.0
Supplement
4.9 0.90 4.41 44.35 9.9
Totals 100 44.35 100.00
![Page 41: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/41.jpg)
41
Simple ration balancing
Pearson’s square : This is a useful technique for balancing one nutrient using two feeds. One feed must have a nutrient concentration above and one feed below the desired nutrient level.
![Page 42: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/42.jpg)
42
Example 1
Balance a ration for 11.5% crude protein using alfalfa hay (17.1% CP) an ground ear corn (9.3% CP).
DM parts DM (%)Alfalfa hay 17.1 2.2 2.2/7.8 28.2
11.5
Ground 9.3 5.6 5.6/7.8 71.8ear corn 7.8 100%Check: 28.2(.171)+71.8(.093) = 11.5%
![Page 43: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/43.jpg)
43
Modified Pearson’s Square
The Pearson’s square method can be expanded to include three or more feeds if the decision is made to “lock in”two or more of the feeds in a fixed proportion.
![Page 44: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/44.jpg)
44
Example 2
Alfalfa hay 20% CPCorn grain 10% CPWheat 12% CP
A decision is made to fix the two grains at 60% corn grain and 40% wheat on a DM basis. How should the alfalfa hay and grain mixture be combined to produce a total ration containing 15% CP
![Page 45: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/45.jpg)
45
Grain protein mix : 0.60(10) + 0.40(12) = 10.8% CPBalance for 15% CP in total ration :
DM parts DM (%)60:40 Grain 10.8 5 5/9.2 54.3Mix 15
Alfalfa 20 4.2 4.2/9.2 45.7Hay 9.2 100%
![Page 46: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/46.jpg)
46
Percentof DM
Final ration : Alfalfa hay 45.7 %Corn grain 54.3 X 0.60 32.6Wheat 54.3 X 0.40 21.7
total 100%
Check : 0.457(20)+0.326(10)+0.217(12) = 15% CPHay Corn Wheat
![Page 47: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/47.jpg)
47
Exercise
Balance a ration for 14.5% CP using corn silage (8.5% CP) and soy bean meal (21% CP).
Balance a ration for 16% CP using a grain mix [30% cotton seed (18% CP) and 70% corn grain (10%)] and alfalfa hay (20% CP)
![Page 48: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/48.jpg)
48
![Page 49: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/49.jpg)
49
Protein Nutrition and Nonprotein Nitrogen
![Page 50: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/50.jpg)
50
Chemical structure of amino acid
H
R C COOH
NH2
![Page 51: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/51.jpg)
51
Protein is required to:
Enhance feed intake and energy useSupply N to the rumen microbes
AmmoniaAmino acidsPeptides
![Page 52: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/52.jpg)
52
Protein is required to:
Supply amino acids for synthesis ofMilk proteinTissue proteinEnzymes, hormones etc.
What are proteins and amino acids?
![Page 53: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/53.jpg)
53
Protein terminology
Intake protein : what the cow eatsSoluble and insoluble – refer to breakdown in water or rumen fluid
Broken down very rapidly in the rumen to ammoniaWhat many of the rumen microbs live on
Degradable and undegradable – refers to whether it ever breaks down in the rumen or not
Broken down in rumenUndegradable protein is also referred to as bypass protein.
![Page 54: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/54.jpg)
54
Protein terminology
Digestible protein – refers to the portion of the protein that is absorbed somewhere in the GI tractMicrobial protein – refers to the portion of the protein produced by the microbes in the rumenTrue protein – made up of amino acids not NPNNonprotein nitrogen – any substance that contains N that is available to the rumen microbes but not made up of amino acids
![Page 55: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/55.jpg)
55
Protein terminology
Intake proteinUndegradable – by passes rumen – 30%Degradable – broken down – 70%
Amino acids (40% of the total)Some bypassDeaminated to NH3 + VFA
NH3 (60% of the total)Used by bacteria to manufacture microbial proteinNH3 + CHO = proteinAbsorbed by rumen, converted to ureaSalivaExcretion
![Page 56: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/56.jpg)
56
Two forms available to cattle
True proteinNon-protein nitrogen
The rumen microbes use these two sources for the production of microbial protein supplies 50% of cow’s protein requirement.
The protein that the microbes produce is much higher quality protein than the feed components from which they are produced.
![Page 57: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/57.jpg)
57
Nonprotein Nitrogen
Several formsAmmoniaUrea281% proteinOther nitrogen compounds – nitrates etc.
Only used in rumenSupplies rumen microbes with NH3Ammonia is either used by the rumen microbes or absorbed by rumen wall
![Page 58: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/58.jpg)
58
Microbial protein synthesis
Protein converted to ammonia, also urea converted to ammonia
Ammonia + a carbon skeleton converted to AA and microbial proteins by microbes
Microbial protein and bypass protein digested in the true stomach and small intestines.
![Page 59: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/59.jpg)
59
Effect of protein on dry matter intake and digestibility
With high producing or rapidly gaining cattle, the benefits of supplemental protein have been accounted for through increased voluntary dry matter intake and increased dry matter digestibility.
![Page 60: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/60.jpg)
60
Crude Protein (CP) = Nitrogen x 6.25Contains Protein & NPN
Available CP
Unavailable CP• Bound or ADF-CP• ↑ when protein is overheated• Mostly undigestible & excreted in feces
Rumen Degradable CPMay be soluble or insoluble
• Used by microbes
Rumen undegradable CPLargely insoluble and
passes to small intestine
Digestible CP in intestines & supplies amino acids to cow
Undigestible CP in intestines & excreted in feces
![Page 61: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/61.jpg)
61
Total Crude Protein
• CP = Nitrogen (N) x 6.25• 100 lb CP = 16 lb N• 100 / 16 = 6.25 • Example: Alfalfa hay =
3% N x 6.25 = 18.75% CP
![Page 62: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/62.jpg)
62
Available ProteinProtein available for digestionShould be 90% or more of CPLess than 90% CP available indicates:
Heat damageExcessive maturity at harvest
![Page 63: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/63.jpg)
63
Unavailable Protein
Protein unavailable for digestionShould be less than 10% of CPIf greater than 10% of CP indicates:
Heat damageMalliard ReactionCarmelized proteinBound proteinADF-N
![Page 64: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/64.jpg)
64
Urea Calculations
1. 46% N in urea X 6.25 = 287% CP2. Obtain % CP from NPN on feed tag3. % CP from NPN / 287 = % Urea
Example:11.5% CP from NPN in 36% CP dairy feed11.5 / 287 = 4% urea4 lbs dairy feed X 0.04 = 0.16 lb urea
Recommendation: Feed < 0.4 lb ureaRecommendation: Feed < 0.4 lb urea
![Page 65: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/65.jpg)
65
Several factors influence the conversion of dietary nitrogen to microbial protein
Rate of passageThe faster it goes through the cow the less opportunity to breakdown
SolubilitySoluble proteins or feedstuffs are more easy to breakdownUrea just add water and its gone
N concentration in the diet/rumenHigher protein in the feed more ammonia in rumenYou don’t make microbes work as hard for their meal
![Page 66: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/66.jpg)
66
Several factors influence the conversion of dietary nitrogen to microbial protein
Energy available in the rumenTake energy to make proteinNH3 needs a carbon skeleton to build AA
Bacteria stimulating factorsVitamins D & BIsoacidsBranched chain fatty acidsyeasts
![Page 67: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/67.jpg)
67
Classes of protein% bypass
Very low bypass UreaCasein
0 – 20
Low bypass Soybean mealPeanut meal
20 – 40
Medium bypass Cottonseed mealAlfalfa mealLinseed mealCornBrewers dried grains
40 – 60
High bypass Meat mealCorn gluten mealBlood mealFeather mealDistillers dried grains
60 or above
![Page 68: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/68.jpg)
68
![Page 69: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/69.jpg)
69
Macrominerals and Trace minerals
![Page 70: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/70.jpg)
70
Macrominerals
Calcium, phosphorus, magnesium, sodium, potassium, and chloride are referred to as major minerals or macrominerals because they comprise a large proportion of body minerals and are required in much larger amounts in the diet than trace minerals.
![Page 71: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/71.jpg)
71
Mineral composition of the mature bovine carcass
Mineral Quantity (g/kg)
Calcium 16.0
Phosphorus 6.5
Potassium 2.0
Sodium 1.5
Chloride 1.2
Magnesium 0.4
![Page 72: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/72.jpg)
72
Mineral deficiency that can lead to PICA
SodiumPotassiumChloridePhosphorus
![Page 73: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/73.jpg)
73
Potassium
RoleThe main functions of potassium are to help maintain the intracellular osmotic pressure and to contribute to the membrane potential.
Potassium is also important in a number of electrically activated phenomena, particularly contraction of cardiac and skeletal muscle.
![Page 74: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/74.jpg)
74
Potassium
PathophysiologyHerbivors eating forage typically ingest large quantities of potassium. Potassium salts are water soluble, and much of the ingested potassium is absorbed. Surplus potassium is excreted via the kidneys.
Most of the K in the body is concentrated inside the cells as a result of the activity of the Na-K ATPase, which pumps K into cells and excretes sodium into the extracellularfluid.
![Page 75: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/75.jpg)
75
Potassium
RequirementsFor herbivors are on the order of 0.5% to 0.8% of the dietary dry matter.
DeficiencyThe first sign is decreased feed intake. With chronic deficiency, the hair coat becomes rough and emaciation develops.
Weakness and cardiac abnormalities are seen with severe deficiency.
![Page 76: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/76.jpg)
76
Potassium
SupplementationRarely necessary.
In high risk situations, K deficiency can be prevented by increasing the amount of roughage in the diet, by mixing KCl with the grain portion of the diet, or by spraying solutions of KCl onto hay.
![Page 77: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/77.jpg)
77
Sodium
RoleSodium is important in controlling the osmotic pressure of extracellularfluid, in the generation of the membrane potential, and the conduction of electrical impulses in nerve and muscle.
![Page 78: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/78.jpg)
78
Sodium
PathophysiologySodium is the only mineral for which a clearly defined appetite exists.
Sodium is one of the few substances that can be detected by taste buds in the tongue.
In times of sodium deficiency, animals actively seek out sources of salt and increase their salt consumption.
![Page 79: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/79.jpg)
79
Sodium
RequirementsNa is of great nutritional importance because grains and some forages are deficient in this element and there are no readily mobilizable stores within the body.
Requirements are estimated to be about 0.1% of the dietary dry matter for most nonlactating farm animals, and these are close to the levels found in grasses and legumes.
![Page 80: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/80.jpg)
80
Sodium
RequirementsHeavily lactating or working animals require up to about 0.2% Na, and these levels are too high to be reliably met by unsupplemented diets.
![Page 81: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/81.jpg)
81
Sodium
DeficiencyNa deficiency is more common in hot environments and in heavily lactating or strenously excercising animals (sodium is lost in milk and sweat).
The initial sign is usually increased salt appetite; animals seek out salt sources and may appear to have pica.
![Page 82: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/82.jpg)
82
Sodium
DeficiencySerum Na concentrations are of limited use in diagnosis of sodium deficiency. In animals with excessive Na losses, water and salt are usually lost together, so the animal becomes dehydrated rather than hyponatremic.
Salivary Na and Na-Ka ratios are much more useful in diagnosis in ruminants.
![Page 83: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/83.jpg)
83
Sodium
DeficiencyDeficient ruminants have Na-K ratios that are always less than 10:1 and sometimes as low as 1:1.
ToxicityNa toxicity is influenced by the availability of water low in dissolved salts.
![Page 84: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/84.jpg)
84
Sodium
ToxicityThere are at least two syndromes produced by salt intoxication –diarrhea and nervous signs.
SupplementationNa and chloride requirements are usually met by offering free-choice salt or by incorporating 0.5% of salt into the whole ration.
![Page 85: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/85.jpg)
85
Sodium : free choice salt consumption of animals
Animal type Intake of loose salt (g/day)
Mature ewes 10-30
Feedlot lambs 5-10
Feedlot beef cattle 10-30
Lactating dairy cows 30-80
![Page 86: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/86.jpg)
86
Chlorine
RoleChlorine mainly exists in the body as the chloride ion. It is the principal anion of the extracellular fluid and an important intracellular ion. Chloride ions are important in the maintenance of osmotic pressure and in electrical phenomena.
![Page 87: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/87.jpg)
87
Chlorine
RequirementFeed levels are satisfactory to meet requirements under many circumstances.
DeficiencyHeavily lactating dairy cows appear to be particularly susceptible because of the losses of chloride in milk and because sodium bicarbonate is often added to buffer the feed.
![Page 88: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/88.jpg)
88
Chlorine
DeficiencySigns of deficiency include loss of weight, decreased food intake, and reduced milk production.
In advance deficiency, signs of dehydration and pica are seen.
ToxicityFree chlorine can be poisonous but only chloride ion and organically bound chloride are found in feedstuffs.
![Page 89: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/89.jpg)
89
Chlorine
SupplementationChloride deficiency can be prevented by ensuring that high-producing dairy cows fed sodium buffers also have access to sufficient chloride.
![Page 90: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/90.jpg)
90
Calcium
RoleCalcium accounts for about 1.5% of body weight and precipitated with phosphate and water, it forms hydroxyapatite, the major mineral of bone and teeth.
Small proportion of calcium that is found outside the skeleton plays a role in metabolic functions.
![Page 91: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/91.jpg)
91
Calcium
PathophysiologyCalcium homeostasis is maintained by three hormones: parathormone, calcitonin, and the vitamin D-derived steroid hormone.
![Page 92: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/92.jpg)
92
Calcium
RequirementsCalcium requirements are particularly high in growing and heavily lactating animals.
Dietary concentrations of calcium are highest in legumes.
![Page 93: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/93.jpg)
93
Calcium
DeficiencyHypocalcemiaParturient paresis or milk fever
ToxicityCalcium has a low toxicity. High concentrations in hay interfere with the absorption of other minerals.
![Page 94: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/94.jpg)
94
Calcium
SupplementationHigh grain diets should always be supplemented with calcium. Calcium supplements may also be needed for animals fed diets based on grass or corn silage, particularly if the animal is growing or lactating.
![Page 95: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/95.jpg)
95
Phosphorus
RolePhosphorus is used throughout the body as a source of rapidly available chemical energy in the form of high-energy phosphate links in creatinephosphates, ATP and other highly phosphorylated nucleotides.
![Page 96: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/96.jpg)
96
Phosphorus
PathophysiologyStimulation of calcium absorption by vitamin D also leads to a secondary increase in phosphorus absorption.
RequirementGrains contain reasonable amounts of phosphorus, particularly in the outer bran layers.
A particular concern to nutritionists has been the digestibility of phytatephosphorus
![Page 97: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/97.jpg)
97
Phosphorus
DeficiencyDeficiency signs are mainly related to phosphorus’s role in the skeleton and in energy metabolism.
Postparturient hemoglobinuria has been linked to phosphorus deficiency.
ToxicityHigh phosphorus diets may suppress the absorption of calcium and can predispose to urolithiasis.
![Page 98: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/98.jpg)
98
Phosphorus
SupplementationDiets are routinely balanced for phosphorus as part of ration formulation.
![Page 99: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/99.jpg)
99
Magnesium
RoleMagnesium is a minor component of bone, but about 70% of total body magnesium is found in the bone.
Magnesium is involved in membrane electrical phenomena and muscle contraction. It is also involved in energy metabolism as a cofactor for several enzymes.
![Page 100: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/100.jpg)
100
Magnesium
PathophysiologyPlasma levels of magnesium are not under close hormonal control. They tend to be maintained around 1 mmol/L (2.5 mg/dl)
RequirementRequirements are greatest in heavily lactating animals. Most feeds contain sufficient magnesium to meet needs, but grains are lower in total magnesium
![Page 101: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/101.jpg)
101
Magnesium
DeficiencyIf hypomagnesemia is sufficiently severe, it produces the disease hypomagnesemic tetany.
ToxicityMagnesium can be toxic at the very high oral intakes associated with therapeutic use. High serum magnesium concentrations depress neuromuscular transmission and cardiac contractility.
![Page 102: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/102.jpg)
102
Magnesium
SupplementationFeeds are often supplemented by mixing with magnesium-containing minerals as part of ration formulation.
![Page 103: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/103.jpg)
103
Trace minerals
Awareness of the importance of trace minerals has increased as sophisticated analytical techniques have been developed.
Overt clinical signs of trace mineral deficiencies or toxicities produce obvious losses in animal health and productivities, but subclinicaldeficiencies or toxicities can produce equally serious losses in production.
![Page 104: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/104.jpg)
104
Normal function
A trace mineral comprises less than 1% of total body ash and is required in the diet at less than 0.1%, or 1 g/kg, feed dry matter.
Trace minerals act primarily as catalysts or activities in enzyme or hormone systems or as integral parts of the structure and function of metalloenzymes.
![Page 105: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/105.jpg)
105
Normal function
The clinical sing or production criterion affected by a trace mineral deficiency depends on the specific physiological function of the metalloezymes.
![Page 106: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/106.jpg)
106
Defining a deficiency state
Most are based on clinical, pathological, and biochemical criteria of animals made deficient using purified diets in controlled studies.
Dietary and tissue trace mineral levels give a good indication that deficiency exists.
![Page 107: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/107.jpg)
107
Defining a deficient state
A trace mineral deficiency is considered
There is an absolute deficiency of the element in the diet.
More than 25 trace mineral–nutrient interactions are recognized.
![Page 108: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/108.jpg)
108
Defining a deficient state
An example of preabsorptive antagonism is the impairment of copper absorption by excessive dietary zinc or iron.
An example of postabsorptive antagonism is the effect of thiomolybdate on copper utilization by the ruminant.
![Page 109: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/109.jpg)
109
Factors that influence trace mineral status
Animal factorsAgeBreedSexSpecies
physiological condition (maintenance, gestation, lactation, growth, and athletic performance)Genetic selection
![Page 110: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/110.jpg)
110
Factors that influence trace mineral status
Plant factorsGenetic selection and bioengineering of plant species can modify plant growth and the ability of food crops to absorb trace minerals from the soil.
![Page 111: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/111.jpg)
111
Factors that influence trace mineral status
Soil composition, moisture, pH, organic matter, depletion or addition of trace minerals, and loss of topsoil modify trace mineral composition of local and regional plant crops.
Irrigation has been related to a depletion of selenium in the topsoil and, consequently, reduction of selenium in the crops grown on these soils.
![Page 112: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/112.jpg)
112
Factors that influence trace mineral status
Environmental factorsDifference in manual, seasonal, and regional precipitation and ambient temperatures can alter a plant’s growth rate and its ability to absorb trance minerals.
![Page 113: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/113.jpg)
113
Factors that influence trace mineral status
Changes secondary to inflammatory disease
Following an insult by an infectious or inflammatory agent, the leukocytes liberate interleukin-1 (leukocyte endogenous mediator).
Interleukin-1 stimulates hepatic synthesis of metallothionein, which binds zinc.
![Page 114: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/114.jpg)
114
Factors that influence trace mineral status
The subsequent depression in serum zinc is related to the degree of toxic insult and is accompanied by enhancement of neutrophil function. These events are followed by synthesis of acute phase reactants, including fibrinogen, haptoglobulin, and alpha-2 globulins (ceruloplasmin).
![Page 115: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/115.jpg)
115
Factors that influence trace mineral status
Increased synthesis of ceruloplasminaccompanies the movement of hepatic copper to peripheral tissues, which produces an elevation of circulating copper concentration.In addition to changes in plasma copper and zinc, plasma iron concentration decreases because granulocytes release apolactoferrin, which binds iron.The iron-lactoferrin then binds to hepatocytic receptors and is made unavailable for microbial growth and toxin production
![Page 116: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/116.jpg)
116
Clinical problems
Trace mineral status is not static but fluctuates throughout the animal’s life.The changes occur in plasma and tissue trace mineral concentration and biochemical function as an animal progresses to a clinically deficient state. It is not until the deficiency results in biochemical changes that disrupt cellular function that clinical signs appear.
![Page 117: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/117.jpg)
117
Clinical problems
The signs exhibited depend on the functions impaired and on the sequence of impairment, thus primary and secondary deficiencies can cause different clinical signs.
![Page 118: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/118.jpg)
118
Diagnosing a deficiency
Several criteria can be used to evaluate the trace mineral status of single animals or herds. These include the following:
A detailed historyA detailed physical examinationA total dietary evaluationTissue evaluation for
The specific trace mineralActivity of metalloenzymes that involve the specific trace minerals, and products, or metaboltes in which the trace mineral or its metalloenzymes is involved.
![Page 119: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/119.jpg)
119
History, clinical examination, and diet evaluation
A thorough history and clinical examination are critical for diagnosis of a suspected trace mineral deficiency.
The diet must be evaluated not only for the suspected trace mineral but also for potential nutrient and trace mineral interactions.
Feed analysis is the most important tool in the diagnosis of trace mineral deficiency as low dietary concentrations indicate a potential for development of a deficiency.
![Page 120: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/120.jpg)
120
Tissue and fluid evaluation
Important aids to diagnosis of trace mineral imbalances include analysis of tissue, blood, serum, and plasma.
Selection of the appropriate tissue is based on the normal distribution of a trace mineral within tissues
![Page 121: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/121.jpg)
121
Tissue and fluid evaluation
Blood, serum, and plasma are the easiest body fluids to sample but may not always be the most useful tissues.
These fluids are used to measure the concentration of the trace mineral directly or indirectly by evaluation of the concentration or the activity of enzymes or hormones altered by a deficiency.
![Page 122: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/122.jpg)
122
Tissue and fluid evaluation
A critical factor in accurate measurement of trace minerals in blood is the use of appropriate collection tubes and anticoagulants.Use of serum rather than plasma can influence the quantification of certain trace minerals. For example, serum copper values for cattle may be lower than plasma copper values because of the precipitation of ceruloplasmincopper in the clot.
![Page 123: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/123.jpg)
123
Tissue and fluid evaluation
Sample storage, sample preparation, and the analytical techniques employed by the laboratory also can alter absolute values obtained.
![Page 124: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/124.jpg)
124
Supplementation
Before recommending trace mineral supplementation, the veterinarian must determine the amount that is needed based on the trace mineral concentrations of the diet, the interactions that may exist with other nutrients, and the group to be supplemented.
![Page 125: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/125.jpg)
125
Recommended upper and lower limits of mineral elements for livestock in mg/kg (ppm) of dry matter in the total ration
Beef Dairy
Mineral Lower Upper Lower Upper
Iron 30 400 100 400
Manganese 25 850 25 850
Copper 10 100 10 100
Zinc 50 500 50 500
Iodine 0.6 20 0.6 20
Selenium 0.1 5 0.1 5
![Page 126: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/126.jpg)
126
Recommended upper and lower limits of mineral elements for livestock in mg/kg (ppm) of dry matter in the total ration
Sheep Horse
Mineral Lower Upper Lower Upper
Iron 30 300 40 100
Manganese 40 850 40 1000
Copper 5 10 10 800
Zinc 50 600 40 500
Iodine 0.6 20 0.1 5
Selenium 0.1 5 0.1 2
![Page 127: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/127.jpg)
127
Supplementation
Oral supplementsParenteral supplements
![Page 128: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/128.jpg)
128
![Page 129: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/129.jpg)
129
Vitamins
Vitamins are micronutrients because they are required in small quantities in the digesta.
In general, vitamins function metabolically either as coenzymes or as hormones.
Requirements are small because most vitamins are recycled within the body.
Absorption is usually limited to the small intestine.
![Page 130: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/130.jpg)
130
Vitamins
Most vertebrates share similar requirements for the same vitamins.
Ruminants and horses are unusual in that the microbial flora of the rumen and large colon produce large amounts of B vitamins.
Vitamin deficiency impairs normal biochemical function within the animal’s body.
![Page 131: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/131.jpg)
131
Vitamins
Vitamins are divided into two main categories, the fat-soluble and water-soluble vitamins.
The fat soluble group consists of vitamins A, D, E, and K. Vitamin A and D function as hormones, whereas E is an antioxidant and K is an enzymatic cofactor.
The water soluble vitamins are the B group vitamins, choline, and vitamin C.
![Page 132: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/132.jpg)
132
Fat soluble vitamins
Vitamin AForms. There are two types of compounds with vitamin A activity. Retinol (vitamin A alcohol) derivatives are the biologically active form of vitamin A in mammals. Plants contain no vitamin A but are rich in carotenoids, which are also known as provitamin A. There are a large number of carotenoids but beta-carotene is the most important.
![Page 133: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/133.jpg)
133
Vitamin A: metabolism
During digestion, carotene is split into two retinol molecules, esterifiedin the intestinal mucosa and transported to the liver. Liver stores vitamin A and regulates plasma retinol concentrations. About half the body’s vitamin A content is found in the liver, stored as palmitate ester.
![Page 134: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/134.jpg)
134
Vitamin A: Role
In retinal, retinol is converted to the aldehyde and used for synthesis of visual pigments.
A major role of vitamin A is maintenance of the functional integrity of simple epithelial surfaces lining the spinal canal, gut, and respiratory and urogenital tracts.
![Page 135: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/135.jpg)
135
Vitamin A: sources
The best sources of vitamin A are the carotenoids in green pasture. Carotenoids are reasonably conserved in the anaerobic condition found in silages.
![Page 136: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/136.jpg)
136
Vitamin A: deficiency
Is most likely to occur in rapidly growing animals fed preserved feeds.
High grain diets with straw as a roughage are particularly apt to cause deficiency.
Reduced growth rate is the early sign of deficiency.
Night blindness and edema of the optic nerve.
Vitamin A-deficient animals also tend to be prone to infections at mucosal surfaces, particularly in the enteric and respiratory tracts.
![Page 137: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/137.jpg)
137
Vitamin A: deficiency
Additional signs that may be observed in cattle are hydrocephalus in neonatal calves, anasarca, heat intolerance, and exophthalmos.
Adult animals are quite resistant to vitamin A deficiency. The main effects appear to be confined to the gestating fetus and reproductive failure in adults.
Diagnosis of vitamin A deficiency depends on the presence of clinical signs and the demonstration of vitamin A depletion.
![Page 138: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/138.jpg)
138
Vitamin A: toxicity
Toxicity occurs when excessive vitamin A intake saturates retinol-binding protein and free vitamin A circulates in plasma.
Signs of toxicity include reduced feed consumption, reduced growth, skin erythema in pigs, and rough hair coats in horses.
![Page 139: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/139.jpg)
139
Vitamin A: supplementation
Routine vitamin supplementation of the grain portion of the diet of animals on high grain, poor quality roughage.
![Page 140: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/140.jpg)
140
Vitamin D
Forms: Vitamin D exists in two forms. Vitamin D2, or ergocalciferol, is formed in plants by ultraviolet irradiation of ergosterol. Vitamin D3, cholecalciferol, is produced in farm animals exposed to sunlight through the action of ultraviolet irradiation on endogenous 7-dehydrocholesterol
![Page 141: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/141.jpg)
141
Vitamin D: metabolism
Both forms of vitamin D are processed by the same enzymes located in the liver and kidney to produce the biologically active 1,25 dihydroxyvitamin D2 or D3. Farm animals can make good use of both forms.
![Page 142: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/142.jpg)
142
Vitamin D: role
1,25 dihydroxyvitamin D is a steroid hormone. It circulates in the plasma bound to a binding protein, diffuses into target cells, and is transported to the nucleus, where it effects gene expression.
Its major effect is to stimulate intestinal calcium absorption; it also improves phosphorus and magnesium absorption.
![Page 143: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/143.jpg)
143
Vitamin D: role
A recently recognized function of calcitriol is immune regulation. It stimulates differentiation of myeloid stem cells into macrophages.
![Page 144: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/144.jpg)
144
Vitamin D: source
Most feedstuffs are low in vitamin D. However, much vitamin D2 is formed when plant material is dried (cured) in the sun; in consequence, hay is a good source.
![Page 145: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/145.jpg)
145
Vitamin D: deficiency
The principal sign of vitamin D deficiency is rickets or osteomalacia(diseases characterized by poorly mineralized bone).
![Page 146: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/146.jpg)
146
Vitamin D: toxicity
Toxicity is seen following long-term administration of dosages that are above 10 times NRC recommendations.
Vitamin D intoxication produces hypercalcemia, hyperphosphatemia, and soft tissue mineralization.
![Page 147: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/147.jpg)
147
Vitamin D: supplementation
Animals that spend most of their time indoors without access to good quality sun-cured hay should be supplemented with vitamin D.
![Page 148: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/148.jpg)
148
Vitamin E: forms
Vitamin E belong to the tocal group of compounds; d-alpha-tocopherol is the most common form of vitamin E found in farm animals and in plants. Only alpha tocopherol has significant biological activity.
![Page 149: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/149.jpg)
149
Vitamin E: role
The major role of vitamin E is as an antioxidant. Its protective effects greatly overlap those of the glutathione peroxidase system, a selenium-containing enzyme that inactivates oxidizing agents. Because of this overlap, symptoms of vitamin E and selenium deficiencies are often similar.
![Page 150: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/150.jpg)
150
Vitamin E: role
Nutritional requirements for vitamin E are increased when the diet is high in polyunsaturated fat, which is susceptible to damage by oxidizing agents.
Exercise increases free radical formation and cell membrane damage as well as susceptibility to vitamin E deficiency.
![Page 151: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/151.jpg)
151
Vitamin E: sources
The major dietary source of vitamin E is fresh green feed and sprouted grain. Hays, silages, grains, and oilseeds are all poor sources, containing 3 to 20 mg of vitamin E per kg. Colostrum is a rich source.
![Page 152: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/152.jpg)
152
Vitamin E: deficiency
Is most likely to be seen in growing herbivores during the winter feeding period or immediately after they are turned out to fresh pasture in spring.
In all species, deficiency causes myodegeneration and steatitis, which is characterized by inflammation of the fatty tissues and results in hard, discolored fat.
![Page 153: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/153.jpg)
153
Vitamin E: deficiency
Degeneration of skeletal muscle (nutritional muscular dystrophy) appears to be triggered by exercise and is seen in lambs, calves, foals, and possibly horses, which are more active than pigs.
![Page 154: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/154.jpg)
154
Vitamin E: toxicity/supplementation
Is essentially nontoxic in animals.
High grain diets are usually supplemented with vitamin E and selenium to prevent vitamin E and selenium deficiency.
Vitamin E supplementation is essential when diets high in polyunsaturated fats.
![Page 155: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/155.jpg)
155
Vitamin K: forms
Vitamin K exists in three forms, K1, K2, K3. K1 is called transplylloquinone. K2exists in the form of a variety of menoquinones and is synthesized by bacteria. K3 is a synthesis of naphthoquinone called menadione.
![Page 156: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/156.jpg)
156
Vitamin K: role
Acts as a cofactor in a post-translational modification of blood clotting factors and proteins involved in the control of calcification in bone.
Reduced vitamin K1 acts as a hydrogen donor in the hepatic conversion of serine protease to active enzymes of blood clotting cascade.
![Page 157: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/157.jpg)
157
Vitamin K: role
The hydroxycoumarin type of anticoagulants, warfarin and dicoumarol, block the conversion of oxidized vitamin K1 back to the active form.
Factor II, V, VII, IX and X are activated by vitamin k, and the major effects of vitamin K deficiency or hydroxycoumarin poisoning are impaired blood clotting manifested as a bleeding tendency.
![Page 158: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/158.jpg)
158
Vitamin K: deficiency
Is uncommon. The vitamin is present in many green feeds. Ruminants synthesize vitamin K in the rumen and absorb it in the small intestine.
The main symptom of dicoumarolpoisoning in cattle is a bleeding tendency. This is usually manifested as hematoma formation and persistent hemorrhage. Hematomas tend to form at trauma points – over the widest part of the ribs, the brisket, and hips.
![Page 159: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/159.jpg)
159
Vitamin K: toxicity
K1 is the least toxic.
Horses appear to be particularly sensitive to vitamin K3 toxicity.
Acute renal failure, renal colic, and death were produced by the administration of a commercial vitamin K3 supplement to horse at the manufacturer’s recommended dosage.
![Page 160: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/160.jpg)
160
Vitamin K: supplementation
Is not normal required in farm animals. The combination of vitamin K1 and enteric synthesis of vitamin K2 meets requirements.
![Page 161: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/161.jpg)
161
Water-soluble vitaminsVitamins BB vitamins function as coenzymes and are water soluble. Many are conserved in the body through efficient recycling mechanisms. The nutritional requirements of farm animals for these vitamins vary. Functional ruminants rarely require supplementation because microbes synthesize large quantities of all the B vitamins in the rumen.
Brewer’s yeast is a good source of all vitamins except B12 and biotin. Rice bran and milk are also good sources of many the B vitamins
![Page 162: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/162.jpg)
162
Thiamin or vitamin B1: role
In cells, thiamin is phosphorylated to the coenzyme thiamin pyrophosphate (TPP), required for the decarboxylationof the glycolytic end product pyruvateto acetyl CoA. This is then used for energy generation in the TAC cycle or for fat synthesis.
![Page 163: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/163.jpg)
163
Thiamin: deficiency
Clinical signs of thiamin deficiency are observed only when dietary thiamin is destroyed by heat or thiaminases in the feed. In ruminants, bacterial thiaminases or inorganic sulfates destroy thiamin in the rumen.
![Page 164: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/164.jpg)
164
Thiamin: deficiency
In ruminants, destruction of thiamin is most common in young animals fed diets high in rapidly fermentable carbohydrate. These diet predispose to ruminal acidosis, which favors thiaminase activity.
Thiamin destruction also occurs when the feed and water is rich in sulfate. In the rumen, this is converted to sulfite, which destroys thiamin.
![Page 165: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/165.jpg)
165
Thiamin: deficiency
In ruminants, neurologic dysfunction is the principal sign of a tissue deficiency of thiamin. Pathological changes seen in the deeper layers of the cerebral cortex give rise to the alternative names for thiamin deficiency of cerebral cortical necrosis (CCN) and polioencephalomalacia.
![Page 166: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/166.jpg)
166
Thiamin: deficiency
In ruminants, blindness is an early clinical sign. This is a cortical blindness caused by dysfunction of cerebral cortices. Pupillary light reflexes are usually intact. This helps differentiate the signs from those caused by vitamin A deficiency, in which the reflexes are absent.
Opisthotonos (dorsiflexion of the head and neck) is an early sign of thiamin deficiency in small ruminants.
![Page 167: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/167.jpg)
167
Thiamin: toxicity
Is virtually nontoxic in an animals. High doses have been claimed to have a sedative effect in horses, but controlled, double blind studies showed no effect from thiamin injection.
![Page 168: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/168.jpg)
168
Thiamin: supplementation
Routine supplementation of diets with thiamin is not usually practiced. However, group supplementation is likely to be worthwhile when some members have shown clinical signs. Routine supplementation may also be indicated in areas with high-sulphatewater.
![Page 169: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/169.jpg)
169
Riboflavin or vitamin B2 : role
Riboflavin is a component of the flavinnucleotides, FAD and FMN. Flavinneucleotides are conenzymes for the flavoprotein group of enzymes. They also form part of the electron transport chain in mitochondria. Deficiency impairs cellular respiration.
![Page 170: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/170.jpg)
170
Riboflavin: source
Green foods such as grass, legumes, and hays are rich in riboflavin. Grains are poor sources and oilseed meals are only slightly better.
![Page 171: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/171.jpg)
171
Riboflavin: deficiency/supplementation
Deficiency of riboflavin leads to anestrus and early embryonic death.
Deficiency is prevented by the routine supplementation of grain-base diet.
![Page 172: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/172.jpg)
172
Pantothenic acid or vitamin B3
Pantothenic acid is a component of conenzyme A, which is required for tricarboxylic acid cycle function and fat metabolism.
Pantothenic acid is found in high levels in alfalfa.
True deficiency syndromes have not been described in ruminants or horses.
In adults, poor reproductive performance is the main effect of deficiency.
![Page 173: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/173.jpg)
173
Niacin
Niacin and nicotinic acid are biologically active as nicotinamide, a component of the coenzymes NAD and NADP. These play a vital role in the TCA cycle and in glycolysis.
Niacin is found in most common feedstuffs at levels of 10 to 200 mg/kg DM. Ruminants synthesize niacin in their rumen, and much of this is absorbed in small intestine.
![Page 174: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/174.jpg)
174
Niacin
High producing dairy cows and rapidly growing beef cattle may benefit from niacin supplementation.
Niacin reduce fat mobilization and decrease the incidence of ketosis and fatty liver.
![Page 175: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/175.jpg)
175
Biotin
Biotin is a coenzyme that takes part in biological carboxylation and decarboxylation reactions it is involved in the tricarboxylic acid, glyconeogenesis, and fat synthesis.
Excellent levels of biotin are found in young green grasses, growing green cereals, and legumes.
![Page 176: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/176.jpg)
176
Biotin
Deficiency affects the integument, particularly the hooves.
Horses may benefit from supplementation if they are afflicted with weak, crumbly hooves.
![Page 177: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/177.jpg)
177
Folate or folacin
Folate is active in the body as tetrahydrofolate. Its main function is in the transfer of the single carbon units that are required for synthesis of purines and pyrimidines, which are components of DNA. Folate can also transfer methyl groups to homocysteine to form methionine.There are complex interrelationships between folate and the other B vitamins.
![Page 178: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/178.jpg)
178
Folate or folacin
Folate and vitamin B12 cooperate in the synthesis of methionine.
Adequate dietary methionine partially overcomes the effects of folatedeficiency.
Source: green feeds are excellent sources of folate.
![Page 179: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/179.jpg)
179
Folate or folacin
Deficiency is not usually seen in animals fed traditional diets. The classical signs of deficiency are poor growth, fading hair coat, hypersegmented neutrophils, large platelets, and macrocytic anemia.The combination of dietary folate and synthesis in the gut uaually supplies sufficient folate to farm animals without the need for further supplementation.
![Page 180: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/180.jpg)
180
Vitamin B12
Cobalamins consist of a nucleoside side chani and a corrinoid ring containing a central cobalt molecule. Only cobalamins are biologically active in animal tissue.
Vitamin B12 functions as a coenzyme in transmethylation reactions, and deficiency impairs DNA synthesis. B12 is also required for TCA cycle function.
![Page 181: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/181.jpg)
181
Vitamin B12
Ruminants directly absorb vitamin B12synthesized by rumen microbes. However, synthesis of vitamin B12 in the gut is dependent on an adequate supply of cobalt. Ruminants are particularly susceptible to cobalt deficiency.
The major signs are a gradual loss of appetite, poor growth, and emaciation.
In lactating cattle, cobalt deficiency produces ketosis.
![Page 182: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/182.jpg)
182
Vitamin B12
Dietarty supplementation with cobalamins is not required in monogastric large animals on conventional diets. Ruminants grazing cobolt-deficient pasture can be supplemented with vitamin B12, but it is usually cheaper to supplement with cobalt.
![Page 183: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/183.jpg)
183
Choline
Choline is not a true B vitamin because it does not function as a coenzyme. It acts as a source of methyl groups and as a component of phospholipids and acetylcholine.
Requirements are high but so is dietary intake. Methionine has a sparing effect on choline.
Deficiency has not been reported in ruminants and horses.
![Page 184: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/184.jpg)
184
Vitamin C
Ascorbic acid functions as a water soluble biologic antioxidant. It also is required for cross-linking of collagen. Poor collagen cross-linking leads to the symptoms of scurvy in human.Farm animals synthesize vitamin C within their tissues. Most fresh forages and leafy plants contain vitamin C. Citrus fruits are particularly good sources of the vitamin.
![Page 185: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/185.jpg)
185
Water: Requirements and Problems
Water accounts for approximately 70% of total body mass.
Animal’s requirements for water are proportional to energy consumption; 1 ml of water for every kcal of metabolizable energy used.
Lactation and high levels of minerals in water and feed also tend to increase water intake.
![Page 186: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/186.jpg)
186
Guideline for water intake:Expected mean water intake in temperate climates
Animal L/day Gal/day
Beef cattle 26 – 66 6.5 – 17
Dairy cattle 38 – 110 9.5 – 28
Horses 30 – 45 7 – 12
Sheep and goats 4 – 15 1 – 4
![Page 187: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/187.jpg)
187
![Page 188: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/188.jpg)
188
Water: Requirements and Problems
Water per se is almost nontoxic, but problems with water arise from contamination with microbes, parasites, minerals, and various poisons.
![Page 189: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/189.jpg)
189
Microbial contaminants
Enteric organismsMineral contaminants
Solubilization of minerals in waterNutritive valueWater quality
Pesticides and herbicides
![Page 190: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/190.jpg)
190
Guidelines for interpretation of total dissolved solids content in waters
Total dissolved solids, mg/L
Interpretation
<1000 Suitable for all classes of livestock
1000 – 1999 Satisfactory for all classes of livestock; may produce transient diarrhea in animals not accustomed to them
2000 – 4999 Temporary water refusal and diarrhea may be seen when animals are introduced to them. May reduce productivity in dairy cattle
5000 – 6999 Likely to reduce productivity in diary cattle. May reduce growth rates. May result in water refusal and diarrhea. Avoid if possible.
7000 – 10000 Unfit for swine, very risky in all other species. Animals may subsist on them. Avoid.
> 10000 Dangerous, avoid.
![Page 191: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/191.jpg)
191
Recommended limits of concentration of some potentially toxic substances in water.
Item Safe upper limit, mg/L
Arsenic, As 0.2
Cadmium, Cd 0.05
Chromium, Cr 1.0
Cobalt, Co 1.0
Copper, Cu 0.5
Fluoride, F 2.0
Lead, Pb 0.1
Mercury, Hg 0.01
Nickel, Ni 1.0
Nitrate – N 100.0
Nitrite – N 10.0
Vanadium, V 0.1
Zinc, Zn 25.0
![Page 192: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/192.jpg)
192
Water requirements
Water is one of the most important essential nutrients. Without good –quality water, production rapidly declined.
Open surface waters are prone to microbial contamination; well waters are prone to mineral contamination. Closed surface water may suffer from poisonous algal blooms.
![Page 193: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/193.jpg)
193
![Page 194: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/194.jpg)
194
Control of feed intake
Regulation of body weight:Animals adapted to ad libitum access to a single ration usually consume amounts sufficient to maintain a constant “set point” body weight.
Intake varies according to individual physiological status and environmental conditions.
Animals that evolved in seasonally variable climates eat amounts sufficient not only to maintain lean body mass but also to store body fat for the lean winter months.
![Page 195: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/195.jpg)
195
Control of feed intake
Dairy cattle and goats have such high nutrient demands for production that feed intake must be maximized in order to maintain adequate body condition.
Reduced intake during late pregnancy is a common problem, particularly in sheep carrying two or more fetuses.
Feed intake is controlled by a complex interplay of metabolic, gastrointestinal, and sensory cues.
![Page 196: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/196.jpg)
196
Control of feed intake
The animal’s current energy status, motivational, and in some cases, previous experience with the feed presented all affect feed intake.
The size and frequency of individual meals are under short-term control but are influenced over time by homeostatic mechanisms that regulate body weight.
It is important to recognize the upper limits of dry matter intake when balancing rations.
![Page 197: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/197.jpg)
197
Control of feed intake
Animals may be unable to consume adequate amounts of a poor-quality forage to meet their nutrient requirements.
Ruminants and horses appear to be able to compensate for sparsely available forage by increasing the rate and duration of eating activity.
![Page 198: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/198.jpg)
198
Percent body weight of dry matter intake possible per day in mature animals
Species Percent body weight
Horses 3.0
Cattle, beef 2.1
Cattle, dairy 2.5
Goats 3.2
Sheep 2.2
![Page 199: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/199.jpg)
199
Control of feed intake
Nutritional wisdomDomestic animals tend to lack “nutritional wisdom”, which is the ability to select from a variety of feeds a diet that is balanced for all nutrients.
Specific appetites is the drive to seek out and consume specific substances based on nutritional deficits. Specific appetites exist for energy, salt, water, and perhaps phosphorus in all species.
![Page 200: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/200.jpg)
200
Control of feed intake
Grazing and eating behaviorForaging behavior consists of both the pattern of meals and the selection of plant types.
Horses, cattle and sheep consume 8 to 14 discrete meals a day, rarely fasting for more than 3 or 4 hours.
![Page 201: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/201.jpg)
201
Control of appetite
Appetite is the desire to seek out and consume feeds; it is not necessarily based on nutritional requirements.
It is determined by a variety of exogenous and endogenous cues.
![Page 202: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/202.jpg)
202
Control of feed intake
Oropharyngeal cuesThe taste, texture, and odor of a feed help to determine its acceptability to a hungry animal.
Flavor preferences differ between species and may be modified by previous experience.
Most domestic livestock prefer sweet and salty flavors, although excess salt (greater than 3%-5%) limits intake in most species.
![Page 203: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/203.jpg)
203
Control of feed intake
Ruminants and horses generally consume more grain or pelleted feed in a single meal than if fed loose hay; more rapid consumption due to reduced chewing time, and faster rate of emptying of grain than hay particles from the rumen or stomach.
The increased rate of passage reduces overall digestibility in cattle, thereby reducing the benefit of greater intake.
![Page 204: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/204.jpg)
204
Control of feed intake
Gastrointestinal cuesThe rate of gastric emptying of feeds appears to be a major limiting factor in the short-term regulation of feed intake.
Nutrients in the gastrointestinal tract stimulate nerves and the release of peptide hormones such as insulin, bombesin, cholecystokinin, and gastrin. These have been strongly implicated in the control of food intake.
![Page 205: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/205.jpg)
205
Control of feed intake
Metabolic cuesPostabsorptive stimuli generated by nutrients and nutrient status influence subsequent feeding activity. Peripheral blood glucose concentration per se does not regulate feeding activity but tends to reflect the degree of hunger.
![Page 206: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/206.jpg)
206
Control of feed intake
Central nervous system cuesThe hypothalamus is considered to be the major integrative center for appetite control. The lateral hypothalamus generates sensations of hungers, and the ventromedialhypothalamus regulates satiety.
![Page 207: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/207.jpg)
207
![Page 208: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/208.jpg)
208
![Page 209: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/209.jpg)
209
Control of feed intake
Feed intake is governed by a wide variety of endogenous stimuli and environmental factors.
It is necessary to consider the relative importance and contribution of each in order to maximize feed efficiency and productivity in large animals.
![Page 210: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/210.jpg)
210
![Page 211: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/211.jpg)
211
Effect of disease on nutritional needs
![Page 212: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/212.jpg)
212
Effects of disease on nutritional needs
Sick animals perform poorly compared with their healthy counterparts.
Economic losses occur both from clinical and subclinical illness, particularly in a large proportion of the animals with a long lasting disease.
![Page 213: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/213.jpg)
213
Disease and animal production
Growth rates and feed conversion ratios often are reduced in animals with subclinicalinfections.
In animals kept for meat production, the time to reach the desired finished weight is increased.
![Page 214: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/214.jpg)
214
Disease and animal production
Parasites reduce the efficiency of the utilization of nutrients through a number of mechanisms. They compete for nutrients within the gut. Some invade the gut wall resulting in inflammation which destroys glandular tissue and reduces the secretion of acid and digestive enzymes. This loss of GI function may reduce the digestibility of nutrients.
![Page 215: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/215.jpg)
215
Disease and animal production
Deworming is particularly important in sheep and growing cattle kept on pasture.
Gastrointestinal infections can run a chronic course and adversely affect nutrient utilization.
![Page 216: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/216.jpg)
216
Nutritional support
Clinical nutrition can be defined as the dietary management of clinically ill animals.The primary goal of clinical nutrition is to optimize nutrient intake, minimize catabolism and utilization of body nutrient stores, and maximize would healing and immune competence in a sick animal.
![Page 217: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/217.jpg)
217
Nutritional support
Recommendations for dietary management of clinically ill large animals are based primarily on data from other species because there are few studies of nutritional needs of injured or ill farm animals.
![Page 218: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/218.jpg)
218
Alterations in nutritional needs
Starvation alone usually decreases metabolic rate, nutrient requirements increase following trauma, sepsis, or stress, even in anorexic animals. The degree of alteration in metabolic rate is dictated by the severity of the insult to the organism.
![Page 219: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/219.jpg)
219
Certain nutrients are of special concern in clinically ill animals
GlucoseTissue utilization of glucose is increased by inflammation.
FatSeverely injured or septic ruminants and horses may utilize volatile fatty acids from fiber fermentation more efficiently than simple carbohydrates from grain.
Horses are tolerate up to 10% total diet dry matter. Lower levels (<5%) are recommended for ruminants.
![Page 220: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/220.jpg)
220
Certain nutrients are of special concern in clinically ill animals
ProteinProtein is greatly altered by inflammation. Activated macrophages release interleukin-1, which stimulates the catabolism of skeletal muscle protein.
![Page 221: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/221.jpg)
221
Certain nutrients are of special concern in clinically ill animals
MineralsTrace mineral concentrations are altered as part of inflammatory response.
VitaminsThiamin, folic acid, and ascorbic acid are utilized and excreted in greater amounts than normal in the hypermetabolic animal.
![Page 222: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/222.jpg)
222
Certain nutrients are of special concern in clinically ill animals
Thiamin is not stored in the body and is normally obtained from the diet or bacterial synthesis. In stressd, anorexic animals, thiamin may be depleted.
Serum folate is reduced in stressed or strenuously exercised horses, and during period of anorexia, disease, or stress.
Vitamin C is stored, and is released during periods of stress, and may be depleted in prolonged illnesses.
![Page 223: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/223.jpg)
223
Estimating caloric needs of clinically ill animals. Multiply the estimated basal maintenance requirements by the appropriate factor
Severity of problem
Clinical problems Mild/minor Moderate Severe
Sepsis 1.15 1.35 1.50
Trauma 1.15 1.35 1.50
Burns 1.20 1.45 1.75
Organ failure 1.10 1.25 1.30
Diarrhea 1.10 1.30 1.50
Tumors 1.10 1.30 1.50
Head trauma 1.50 1.75 2.00
![Page 224: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/224.jpg)
224
Modes of alimentation
Oral supplementationThis is the preferred mode because digestion, absorption, and metabolism of nutrients are enhanced if the animal is allowed to taste, chew, and swallow its feed.
If recommended intakes exceed the maximum voluntary intake of the animal, more concentrated sources of energy may be added to the ration.
![Page 225: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/225.jpg)
225
Modes of alimentation
Grains are excellent sources of energy but generally should not comprise more than 50% of the total ration.
Anorexia. Clinically ill animals are frequently anorexia. A variety of feeds should be offered in small amounts to determine preferences.
![Page 226: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/226.jpg)
226
Modes of alimentation
Intragastric supplementation.If an animal is unwilling or unable to eat and has fairly normal GI function, supplemental nutrients may be provided by stomach tube. Complete pelleted feeds soaked in water may be used.
![Page 227: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/227.jpg)
227
Modes of alimentationIntravenous alimentation.
Intravenous supplementation of energy and protein in adult large animals is possible when absolutely necessary.
Candidates for IV nutrient supplementation include animals with severe, acute diarrhea or anterior enteritis.
Complications associated with intravenous feeding include septicemia, thrombosis, hyperglycemia, and glucosuria.
![Page 228: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/228.jpg)
228
![Page 229: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/229.jpg)
229
Feeding the beef cow for optimal production
The four principal factors influencing the profitability of a cow-calf operation are
Weaning weightsPercentage of cows weaning calvesCost of maintaining the cow per yearPrice of calves
![Page 230: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/230.jpg)
230
Feeding the beef cow for optimal production
Factors controlling the kg of calf weaned per cow are
The reproductive efficiency of the cowsCalf survival
Genetic growth potential of the calf optimized by the cow and measured as weaning weight.
![Page 231: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/231.jpg)
231
Effect of nutrition on reproduction and calf growth
Nutrition plays a key role in influencing both conception rates and the percentage of cows cycling during the breeding season.
The quality and quantity of pasture and range has a dramatic influence on the overall conception rate of the cows.
![Page 232: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/232.jpg)
232
Effect of nutrition on reproduction and calf growth
Prepartum nutritionThe level of prepartum nutrition –both protein and particularly energy – has a major impact on how soon the cows cycle after calving.
Also impact on the birth weight, calf survival, subsequent milk production, and growth rate of the calf.
![Page 233: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/233.jpg)
233
Effect of nutrition on reproduction and calf growth
Postpartum nutritionPostcalving nutrition, particularly energy, has its greatest effect on calf growth and cow conception rates.
![Page 234: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/234.jpg)
234
Effect of nutrition on reproduction and calf growth
Factors influencing nutritional requirements
Effect of stage of production on nutrient requirementsCow conditionCow size and milk productionEnvironmental effects
![Page 235: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/235.jpg)
235
![Page 236: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/236.jpg)
236
Colostrum and feeding management of dairy calf and nutrition of dairy replacement heifers
![Page 237: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/237.jpg)
237
Heifer inventory and the economics of replacement rearing
The early development period is critical to a healthy heifer.
Ration should be specifically
formulated for weight gains during strategic time periods of development.
![Page 238: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/238.jpg)
238
Heifer inventory and the economics of replacement rearing
Heifers should weigh 775 to 800 pounds at 14 to 15 months for breeding to calve at 24 to 25 months.
Heifers should gain 1.8 pounds per day of age to calve at 24 months weighing 1,350 pounds.
![Page 239: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/239.jpg)
239
Heifer inventory and the economics of replacement rearing
Use superior AI sires on replacement
heifers for breeding.
Weight is more critical than age at
calving in relation to milk production
Monitor weight, height, body condition
score at calving to reflect heifer
development.
![Page 240: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/240.jpg)
240
Should I raise my own heifers or have them custom-raised?
1. Do you currently have enough labor to
raise your own replacements?
2. Are your facilities adequate to raise
heifers? Do you have adequate
housing, land, and feed resources to do
a good job?
![Page 241: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/241.jpg)
241
Should I raise my own heifers or have them custom-raised?
3. Under your current system are your
heifers freshening at 24 months of and
at 1,250 lb (for Holsteins)?
4. Do you have enough capital to pay
someone else to raise your heifers?
5. How could you use your current
facilities that are being used to raise
heifers?
![Page 242: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/242.jpg)
242
Management Component
Calf care from birth to weaning.
Heifer care from weaning to calving.
![Page 243: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/243.jpg)
243
Calf care from birth to weaning
Facilitieshousingindividual pens
Feeding and nutritioncolostrum managementcalf nutritionwater
![Page 244: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/244.jpg)
244
Colostrum Feeding Do’s and Don’ts
Item Do Don’tCalving area Allow cows to calve in
a clean, dry maternitypen or on a cleanpasture.
Forget to separate close-up cows from the herd,or forget to clean pensbetween cows.
Separatingcalves
Separate calves fromthe dam as soon aspossible.
Leave the calf and damtogether for more thanan hour.
![Page 245: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/245.jpg)
245
Colostrum Feeding Do’s and Don’tsItem Do Don’tColostrumFeeding
Feed first feeding ofcolostrum as soon aspossible (within 1 hour).
Use fresh colostrumfrom the dam if goodquality.
Use colostrum fromcows that are leakingcolostrum from theirudder prior to or atcalving.Use colostrum thatcontains blood or ismastitis.
![Page 246: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/246.jpg)
246
Colostrum Feeding Do’s and Don’tsItem Do Don’tColostrumFeeding
Feed at least 3 quarts ofcolostrum in the firstfeeding and again 12 hourslaterFeed 3 quarts of colostrumat each feeding if the calf is> 100 lb.
Wait for the calf to get upon its own and nurse.
Allow the calf to get itscolostrum from nursingthe dam or feed less than2 quarts per feeding
![Page 247: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/247.jpg)
247
Colostrum Feeding Do’s and Don’tsItem Do Don’tColostrumFeeding
Use an esophageal feeder ifthe calf will not consumesufficient colostrum.
Use a broken or dirtyesophageal feeder.
ColostrumQuality
Measure colostrum qualitywith a colostrometer beforeuse
Use thin, waterycolostrum, especially iffrom a heifer
![Page 248: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/248.jpg)
248
Colostrum Feeding Do’s and Don’ts
Item Do Don’tColostrumQuality
Save good qualitycolostrum by freezing in 1or 2 quart bottles. Thawcolostrum carefully topreserve antibodies.
Place frozen colostrum inextremely hot water orthaw in a microwaveunder high power for > 1min ata time (thisdestroys antibodies)
![Page 249: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/249.jpg)
249
Colostrum Feeding Do’s and Don’ts
Item Do Don’tColostrumQuality
Use fair and poor qualitycolostrum and transitionmilk only for older calves.
Feed poor qualitycolostrum at the first 2feedings.
Othermanage-ment tasks
Dip navels with tincture ofiodine as soon as possible.
Use teat dip or othersolution rather thantincture of iodine to dipnavels
![Page 250: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/250.jpg)
250
Colostrum Feeding Do’s and Don’ts
Item Do Don’tOthermanage-ment tasks
Put calf in an isolated, dry,and draft-freeenvironment.Continue to feed lowerquality colostrum ortransition milk for 2 to 3days after birth.
Group calves together orhouse calves in a wet ordrafty environment.
![Page 251: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/251.jpg)
251
Calf care from birth to weaning
Health care and managementumbilical cord.sanitation.preventive health care programs.extra teat removal.dehorning.parasites.identification.
![Page 252: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/252.jpg)
252
![Page 253: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/253.jpg)
253
Heifer care from weaning to calving
FacilitiesFeeding and nutritionHealth care and management
age at weaning.breeding.Identification and records.vaccination programs.parasite and fly control.treatment facilities.
![Page 254: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/254.jpg)
254
Average daily gains and age at puberty
Average daily gain(pound/day)
Age in monthsheifers reach
puberty 2.0 (gains are excessive= fat deposits in udder)
7
1.5 and 1.7 (average gainsbetween 3 and 9 months
9
1.2 (too low average dailygains)
12
0.8 (puberty delayed= delayed calving
14
![Page 255: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/255.jpg)
255
Heifer puberty
Breed Weight(pounds)
Age(months)
Holstein 785 14 to 15Brown Swiss 785 14 to 15Milking Shorthorn 750 14 to 15Guernsey 685 14 to 15Aryshire 685 14 to 15Jersey 550 12 to 13
![Page 256: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/256.jpg)
256
Monitoring Dairy Heifer Growth
Insure that calves are on target to reach
a weight of 1,350 pounds at calvinga height of 53 inches at the shouldera BCS of 3.25-3.5 at 24 months of age
![Page 257: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/257.jpg)
257
![Page 258: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/258.jpg)
258
Monitoring and graphing heifer growth
IF WE CAN MEASURE IT,WE CAN MANAGE IT
![Page 259: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/259.jpg)
259
![Page 260: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/260.jpg)
260
![Page 261: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/261.jpg)
261
![Page 262: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/262.jpg)
262
![Page 263: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/263.jpg)
263
Effect of calving age on size of replacement herd
Age at calving Month % changefrom 24 months
22232425262728
-8.4-4.2
0+4.2+8.4
+12.6+16.8
![Page 264: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/264.jpg)
264
Nutrition during the first 3 wk of life
Timely feeding of adequate quantities of high-quality colostrum is essential to the future well-being of the calf.
The whole milk requirement for maintenance of a 45-kg calf is calculated to be 3.3 L/day.
For 450 g of growth/day, 5 L or about 600 g of DM are required.
![Page 265: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/265.jpg)
265
Nutrition during the first 3 wk of life
Rumen function develops in response to solid feed consumption.
The rumen can be functional as early as 2 wk and is functional in all calves by 6 to 8 wk of age if they are offered solid feed.
![Page 266: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/266.jpg)
266
Milk and milk substitues
Colostrum
Fresh cow milk – milk secretion from cows in the first 3 days of lactation
Whole milk – ideal feed for the first 3 wk of life
Mastitic milk – if possible, it should be fed only to older calves.
![Page 267: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/267.jpg)
267
Milk and milk substitues
return milk – is probably best feed to the calves over 3 wk-old
Milk replacer – digestibility is dependent on the protein source and the processing of the milk protein
![Page 268: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/268.jpg)
268
Milk and milk substitues
Quantity of milk – newborn calves should be fed 8 to 10% of their BW of whole milk or its equivalent. Twice-a-day feeding leads to better daily gain than once-a-day feeding
Calf starter – should supply at least 18% CP (NPN should not be used), CF should be 6 to 8%
![Page 269: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/269.jpg)
269
Nutrition from 3 wk to weaning
A period of increasing starter consumption and decreasing dependence on milk
Concentrate intake increases from 0.5 kg at 3 wk of age to 3 kg at 12 wk of age
Concentrate consumption increases rapidly when milk feeding is stopped.
![Page 270: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/270.jpg)
270
Nutrition from 3 wk to weaning
Milk feeding may be stopped as early as 30 d of age – more common to continue for about 55 d
Hay may be fed to calves before weaning, but it is optional
![Page 271: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/271.jpg)
271
Nutrition from weaning to breeding
Newly weaned calves should continue to get calf starter – grower mix containing 16% CP is fed.Do not overfeed with forages.
![Page 272: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/272.jpg)
272
Nutrition from breeding to calving
Heifer may be fed straight forage during this period, provided that the basic nutrient requirements are met. The CP level of the total ration should not be less than 12%.
![Page 273: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/273.jpg)
273
Feeding the dairy cow for optimal production
![Page 274: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/274.jpg)
274
0 1 2 3 4 5 6 7 8 9 10 11 12Month
Phase 4
Phas
e 1
Phase 6Ph
ase
3Phase 5
Phas
e 2
Dry Matter Intake
Body WeightBody Weight
Milk Production
Peak DMIPeak Milk Tail End
Fresh
Far Off
Close Up
![Page 275: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/275.jpg)
275
Energy needs
Missmanagement of energy feeding
in dairy rations can be costly.
Overfeeding during late lactation
and dry periods causes excessive
fattening and subsequent metabolic
problems.
![Page 276: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/276.jpg)
276
Energy needs
Undernutrition in early lactation
is another common mistake made on
dairy farms.
Sources of energy also affects
milk yield and composition.
![Page 277: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/277.jpg)
277
Early lactation
Provide an adequate balance of necessary
nutrients (protein, minerals, and
vitamins).
Ensure that fiber is sufficient to maintain
optimal rumen fermentation (20-22% ADF on a
DM basis)
Make sure ration chewy and sweet.
![Page 278: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/278.jpg)
278
Mid to late lactation
Milk production decrease energy
concentration of the diet may be
decreased, depending on production
and body condition score.
![Page 279: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/279.jpg)
279
Grouping of cows for maximum milk production
Large herd practical ; small
herd not
Nutritional requirement managed
Milk production satisfied
Routine milking process
beneficial
![Page 280: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/280.jpg)
280
Body condition scoring (BCS)
When?
Timing of body scoring is arbitrary.
Convenient to score cattle at the time of feed level changes.
At freshening, peak lactation, mid lactation, and drying off.
![Page 281: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/281.jpg)
281
Body condition score (BCS)
1 - 5 scale1 = very thin
5 = excessively fat
![Page 282: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/282.jpg)
282
![Page 283: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/283.jpg)
283
1.Condition scoring scale2. Look at example cows3. Discuss research on
condition scoring4. Recommendations for
condition score at various stages of lactation
![Page 284: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/284.jpg)
284
Goal : To minimize body condition fluctuation throughout lactation.
To minimize the number of problem cows (too fat or too thin)
![Page 285: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/285.jpg)
285
![Page 286: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/286.jpg)
286
![Page 287: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/287.jpg)
287
![Page 288: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/288.jpg)
288
Condition score 1
Individual vertebrae are distinct along the top line; ends of short ribs are prominent, and give a distinctly shelf-like appearance. Hips and pin bone are sharp; severe depressions show between hips and pins, and between hooks. A deep V-shaped cavity is below the tailheadand between the pin bones.
![Page 289: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/289.jpg)
289
![Page 290: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/290.jpg)
290
![Page 291: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/291.jpg)
291
Condition score 2
Short ribs can be seen, and the ‘shelf’ still is visible. While hips and pins still are prominent, individual vertebrae along the top line are not distinct to the eye. The depression around the tail head and pin bones is more V-shaped.
![Page 292: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/292.jpg)
292
![Page 293: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/293.jpg)
293
![Page 294: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/294.jpg)
294
Condition score 3
The short ribs appear smooth, with no shelf effect. The backbone is a rounded ridge; individual vertebrae are rounded and smooth; the area between pin bones and tail head has smoothed out.
![Page 295: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/295.jpg)
295
![Page 296: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/296.jpg)
296
![Page 297: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/297.jpg)
297
![Page 298: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/298.jpg)
298
![Page 299: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/299.jpg)
299
Condition score 4
Short ribs are smooth and rounded; no shelf effect. The chine region is rounded and smooth; loin and rump appear flat. Hips are rounded and flat in-between. There is a rounded appearance over the tail head and pin bone area, with evidence of fat deposit.
![Page 300: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/300.jpg)
300
![Page 301: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/301.jpg)
301
![Page 302: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/302.jpg)
302
Condition score 5
The backbone is covered by a thick layer of fat, as are the short ribs. Hips and pins are not apparent, and the areas between them are rounded; the tail head is surrounded by fat.
![Page 303: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/303.jpg)
303
![Page 304: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/304.jpg)
304
![Page 305: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/305.jpg)
305
Target scores for stages of lactation: Cows at calving
Recommended score: 3+ to 4-
Nutritional objective: allow cows to calve with adequate, but not excessive, body-fat reserves.
Score below 3+ indicate inadequate energy supply during late lactation and/or the dry period. Failure to replenish energy reserves will limit milk production during the upcoming lactation.
![Page 306: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/306.jpg)
306
Target scores for stages of lactation: Cows at calving
Score above4- indicate too high
energy intake during late lactation
and/or the dry period. Separate dry
cows from the milking herd and feed
them a low-energy ration with
adequate, but not excessive, protein,
minerals, and vitamins.
![Page 307: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/307.jpg)
307
Target scores for stages of lactation: Early lactation
Recommended score : 3- to 3
Nutritional objective : maximize intake of a high-energy ration to minimize changes in body condition and counteract negative energy balance. Ration must contain adequate protein to support peak milk production.
![Page 308: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/308.jpg)
308
Target scores for stages of lactation: Early lactation
Scores below 3-very high producers may drop to 2+ and are not a problem.
Thin cows that are not high producers are not getting enough energy. Be sure that all nutrients are balanced properly and that dry-matter and water intakes are adequate.
![Page 309: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/309.jpg)
309
Target scores for stages of lactation: Early lactation
Cows have good body condition (3 to 3+), but production is not as high as expected. Check for inadequate intakes of protein, minerals, or water.
![Page 310: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/310.jpg)
310
Target scores for stages of lactation: Mid-lactation
Recommended score : 3
Nutritional objective : maintain body condition at this score to maximize milk production.
Scores below 3 indicate inadequate energy. Check early lactation ration, because problem began there.
Scores above 3+, reduce energy intake to avoid overconditioning.
![Page 311: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/311.jpg)
311
Target scores for stages of lactation: Late lactation
Recommended score : 3 aim for 3+ and 4- at time of dry off.
Nutritional objectives :
replenish energy and fat reserves to prepare cow for next lactation.
Avoid overconditioning.
![Page 312: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/312.jpg)
312
Target scores for stages of lactation: Late lactation
Scores below 3+ at dry off mean cows are receiving inadequate energy. Check to see that early- and mid-lactation cows are receiving enough energy, since problem may have begun there.
For scores above 4- at dry off, reduce energy intake during late lactation.
![Page 313: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/313.jpg)
313
Target scores for stages of lactation: Dry
Recommended score : 3+ to 4-
Nutritional objectives :
Maintain body condition in recommended range.
Feed low-energy ration that provides adequate, but not excessive, amounts of protein, vitamins, and minerals.
![Page 314: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/314.jpg)
314
Target scores for stages of lactation: Dry
Scores below 3+
Increase energy intake. Inadequate body-fat reserves can decrease milk production in upcoming lactation.
Increase energy content of late-lactation ration. Body-fat reserves should be replaced at that time.
![Page 315: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/315.jpg)
315
Target scores for stages of lactation: Dry
Scores above 4-
Reduce energy intake of dry cows while maintaining adequate levels of protein, vitamins, and minerals.
Reduce energy intake of late-lactation cows, because the problem may have begun there.
![Page 316: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/316.jpg)
316
Target scores for stages of lactation: Heifers
Recommended score : 3- to 3+
Nutritional objectives:Maintain body condition in recommended range.
Feed a balanced ration that provides adequate but not excessive amounts of energy, protein, vitamins, and minerals.
![Page 317: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/317.jpg)
317
Target scores for stages of lactation: Heifers
Scores below 3- may indicate a
nutritional problem. If heifers are
allowed to become too thin, they will
not grow at the proper rate and may
have reproductive problems later on.
Score above 3+ have been shown to be
associated with a greater fat
infiltration in the mammary glands of
heifers at puberty.
![Page 318: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/318.jpg)
318
Good nutritional management guidelines to keep metabolic disease low include:
Feed a ration balanced for protein, energy, fiber, vitamins and minerals.
Group cows according to production and adjust body condition accordingly during lactation.
![Page 319: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/319.jpg)
319
Good nutritional management guidelines to keep metabolic disease low include:
Dry cows off at a 3.5 body condition score, the desired score for the dry period and at weaning. Maintain this condition throughout the dry period, avoiding the fat cow syndrome and related metabolic disorders.Provide exercise for dry cows.
![Page 320: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/320.jpg)
320
Good nutritional management guidelines to keep metabolic disease low include:
Limit grain feeding prior to calving to about 0.5 kg increase per day starting about 15 days ahead of calving. By the 15th day you’ll be feeding 6 kg.
Maintain a balance of forage-to-concentrate in the total ration after calving to maximize intake but to prevent digestive upsets during adaptation to the peak lactation ration.
![Page 321: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/321.jpg)
321
Good nutritional management guidelines to keep metabolic disease low include:
Feed grass hay, haylage or pasture to dry cows to minimize calcium intake to prevent milk fever.
Limit corn silage fed to dry cows to 15-20 kg daily, and feed 5 kg of grass hay or equivalent forage.
Limit concentrate feeding after peak lactation and conception have occurred.
![Page 322: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/322.jpg)
322
Good nutritional management guidelines to keep metabolic disease low include:
Maintain a 12- to 13-month calving interval to avoid long dry periods by providing good health and nutrition measures and expert reproductive practices.
![Page 323: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/323.jpg)
323
การจัดการโคระยะแหงนม
แมโคควรไดรับอาหารหยาบในชวงนี้ประมาณ 1% ของน้ําหนกัตัว เพื่อใหกระเพาะรูเมนสามารถทํางานไดเปนปกติ
พืชอาหารหยาบทีม่ีโปรตีนสูงควรใชประมาณไมเกินครึ่งหนึ่งของอาหารหยาบทั้งหมด
ขาวโพดหมักควรใชอยางจํากัดในระยะนี้เพื่อปองกันแมโคไดรับอาหารพลังงานมากเกินและจะสงผลใหแมโคอวนมากเกินไปในระยะนี้
![Page 324: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/324.jpg)
324
การจัดการโคระยะแหงนม
แมโคควรไดรับอาหารขนอยางนอย 1 กิโลกรัมเพื่อเปนแหลงวิตามินและแรธาตุที่จําเปนสําหรับแมโค
แมโคอาจไดรับอาหารขนเพิ่มขึ้นตามคะแนนรางกาย ความตองการสารอาหาร คุณภาพและการกินไดของ
อาหารหยาบ สภาวะเครียดจากสิ่งแวดลอม
![Page 325: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/325.jpg)
325
การจดัการโคระยะใกลคลอดและระยะหลงัคลอด
Transition period เริ่มตั้งแต 3 สัปดาหกอนคลอดจนถึง 3สัปดาหหลังคลอด เปนชวงที่มีการเปลี่ยนแปลงทางสรีระวิทยาและเมตาโบลิซึมของรางกาย ตลอดจนการเปลี่ยนแปลงทางดานโภชนาการ
![Page 326: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/326.jpg)
326
ชีววทิยาของโคในระหวาง transition period
การกินได แมโคในระยะนี้จะมีการกินไดลดลง ซึ่งสาเหตุมาจากการเติบโตอยางรวดเร็วของลูกโคที่เบียดบังพื้นที่
ของกระเพาะรูเมน นอกจากนี้การเปลี่ยนแปลงของฮอรโมนในชวงนี้ยังทําใหความอยากอาหารของแมโค
ลดลงดวย
![Page 327: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/327.jpg)
327
ปจจัยที่มีอิทธิพลตอการกินไดของโค
สิ่งแวดลอม ตวัโค อาหาร
อุณหภมูิ ปริมาณน้ํานม ลักษณะทางกายภาพ
การถายเทอากาศ ขนาดรางกายโค ความนากิน
ความชื้น สถานภาพของฮอรโมน ปริมาณเยื่อไยในอาหาร
การใหอาหารตอวัน สายพันธุ โภชนะสมดุล
ปริมาณน้ํา คะแนนรางกาย ความชื้นในอาหาร
การระบายความรอน สถานภาพของสขุภาพ คุณคาของอาหารหยาบ
![Page 328: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/328.jpg)
328
ชีววทิยาของโคในระหวาง transition period
การเปลี่ยนแปลงทางสรีระ การเติบโตอยางรวดเร็วของลูกในทอง การพัฒนาของเตานมเพื่อเริ่มขบวนการสราง
น้ํานม สงผลตอขบวนการเมตาโบลิซึมของแมโค การลดลงของระดับกลูโคส อินซลูิน ในเลือด การเพิ่มขึ้นของระดับกรดไขมัน และสารคีโตนในเลือด
![Page 329: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/329.jpg)
329
ชีววทิยาของโคในระหวาง transition period
การทํางานของกระเพาะรูเมน การปรับตัวของกระเพาะรูเมนตออาหารที่แมโคไดรับในระยะนี้โดยสัมพันธกับการ
จัดการอาหาร การปรับตัวของกระเพาะรูเมนเพื่อใหคุนเคยกับอาหารขนจะใชเวลาประมาณ 3-4 สัปดาห
![Page 330: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/330.jpg)
330
ชีววทิยาของโคในระหวาง transition period
ปญหาสุขภาพที่สัมพันธกับชวง transition period
ความผิดปกติทีเ่กี่ยวของกับเมตาโบลซิึม ไดแก ปญหาการ
สะสมไขมันในตับ คีโตซสี ภาวะรเูมนเปนกรด เปนตน
ความผิดปกติทีเ่กี่ยวของกับแรธาตุ ไดแก ไขน้าํนม เปนตน
ความผิดปกติทีเ่กี่ยวของกับระบบภูมิคุมกัน ไดแก รกคาง เตานมอักเสบ เปนตน
![Page 331: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/331.jpg)
331
การจัดการอาหารในชวง transition period
ความตองการพลังงานและภาวะพลังงานขาดสมดุลแมโคตั้งทองระยะสุดทายมีความตองการพลังงานตั้งแต 1.3-1.5 เทาของพลังงานเพื่อการดํารงชีวติความไมสมดลุกันระหวางพลังงานที่แมโคไดรับจากอาหารกบัพลังงานทีต่องการเพื่อการสรางน้ํานม ทาํใหแมโคเกิดภาวะพลังงานขาดสมดุล (negative energy balance)ความรุนแรงของพลังงานขาดสมดุลในชวงหลังคลอดขึ้นอยูกับปรมิาณการกินไดของโคและคะแนนรางกายของแมโคในระยะกอนคลอด
![Page 332: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/332.jpg)
332
-80
-60
-40
-20
0
20
40
60
80
100
-50 -30 -10 10 30 50 70 90 110 130
Day from parturition
Ener
gy b
alan
ce (M
J/d)
Parturition
![Page 333: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/333.jpg)
333
**
**
0.00
0.50
1.00
1.50
2.00
-2 -1 0 1 2 3 4
Week from parturition
NEF
A (m
mol
/L)
Parturition
A
![Page 334: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/334.jpg)
334
*
* * *
0
60
120
180
-2 -1 0 1 2 3 4
Week from parturition
TAG
(mg/
g of
live
r)Parturition
B
![Page 335: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/335.jpg)
335
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันนอย)
2 สัปดาหกอนคลอด
![Page 336: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/336.jpg)
336
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันนอย)
1 สัปดาหหลังคลอด
![Page 337: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/337.jpg)
337
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันนอย)
2 สัปดาหหลังคลอด
![Page 338: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/338.jpg)
338
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันนอย)
3 สัปดาหหลังคลอด
![Page 339: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/339.jpg)
339
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันที่รุนแรง)
2 สปัดาหกอนคลอด
![Page 340: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/340.jpg)
340
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันที่รุนแรง)
1 สัปดาหหลังคลอด
![Page 341: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/341.jpg)
341
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันที่รุนแรง)
2 สัปดาหหลังคลอด
![Page 342: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/342.jpg)
342
การสะสมของไขมันในตับโคนมกอนและหลังคลอด (สําหรับโคที่มีการสะสมของไขมันที่รุนแรง)
3 สัปดาหหลังคลอด
![Page 343: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/343.jpg)
343
การจัดการในระยะ transition period
ความตองการพลงังานและภาวะพลงังานขาดสมดุล
พลังงานขาดสมดุล
อินซูลิน
การสลายไขมัน
ไขมันสะสมในตับ
การทํางานของตับ
กรดไขมันในเลือด
พิษตอรังไข และ ฟอลลิเคิล
พิษตออวัยวะอื่นๆ
![Page 344: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/344.jpg)
344
อาหารผสมรวม : สุขภาพและการใหน้ํานม
อาหารผสมรวมหมายถึงอาหารที่มีการผสมชนิดของวัตถุดิบอาหารที่ใชประกอบกันเปนอาหารโคทั้งหมดเขาดวยกัน โดยมีโภชนะที่โคตองการอยูอยางสมดุล
![Page 345: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/345.jpg)
345
อาหารผสมรวม
อาหารขน + อาหารหยาบ + อาหารเสริมอื่นๆ
![Page 346: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/346.jpg)
346
เครื่องผสมอาหาร TMR
![Page 347: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/347.jpg)
347
เครื่องผสมอาหาร TMR ชนิดใบพดัตามแนวนอน
![Page 348: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/348.jpg)
348
เครื่องผสมอาหาร TMR ชนิดใบพดัตามแนวนอน
![Page 349: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/349.jpg)
349
เครื่องผสมอาหาร TMR ชนิดใบพดัตามแนวตั้ง
![Page 350: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/350.jpg)
350
พืชอาหารหมัก (Silage)
![Page 351: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/351.jpg)
351
พืชอาหารหมัก (Silage)
![Page 352: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/352.jpg)
352
พืชอาหารหมัก (Silage)
![Page 353: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/353.jpg)
353
หญาแหง (grass hay)
![Page 354: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/354.jpg)
354
ภาวะกรด-ดางในกระเพาะหมัก
กระเพาะหมักจะมสีภาวะเปนกรดเพิ่มขึ้นในระหวางที่โคกินอาหารขน และความเปนกรดจะลดลงภายหลงัจากโคไดรบัอาหารหยาบหรือระหวางกินอาหารหยาบโดยปกตภิาวะกรด-ดางในกระเพาะหมักจะมีคาประมาณ 5.5-7
![Page 355: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/355.jpg)
355
ภาวะกรด-ดางในกระเพาะหมัก
ภายหลงักินอาหารขนใหมๆ คาความเปนกรด-ดางอาจลดลง และมีคาประมาณ 4-5
![Page 356: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/356.jpg)
356
การควบคุมภาวะกรด-ดางในกระเพาะหมัก
การเคี้ยวเอื้องจะชวยปรับภาวะกรด-ดางในกระเพาะหมักใหอยูในสภาวะที่การทํางานของเชื้อจุลินทรียตางๆ สามารถเกิดขึ้นไดอยางเปนปกติ
การเคี้ยวเอื้องลดลงจะทําใหกระเพาะหมักมีภาวะเปนกรดเพิ่มขึ้น ทําใหเกิดสภาวะที่เรียกวาแอซิโดซีส ซึ่งจะสงผลตอการผลิตและสุขภาพของโค
![Page 357: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/357.jpg)
357
ผลของระดับอาหารขนและลักษณะของอาหารหยาบตอขบวนการเคี้ยวเอื้อง การหลัง่น้าํลายและปริมาณไขมันนม
อาหารขน : อาหารหยาบ
การเคี้ยวเอื้อง (นาที/วนั)
การหลั่งน้ําลาย (แกลลอน/วัน)
อะซิเตต :โพรพิออเนต
เปอรเซ็นตไขมันนม
50:50 720 42.3 3.7 3.5
30:70 554 30.9 2.2 2.9
ชนิดอาหารหยาบ
60:40 ขนาดยาว 704 39.6 3.6 3.5
60:40 อัดเม็ด 219 13.2 2.1 2.9
![Page 358: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/358.jpg)
358
สรปุ
โคนมทีม่สีุขภาพดจีะใหผลผลติน้าํนมทีด่แีละมีคุณภาพ
โคนมทีม่สีุขภาพดจีะมคีวามสมบรูณพันธุดี
อาหาร สุขภาพ ผลผลติ
ความสมบรูณพันธุ
![Page 359: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/359.jpg)
359
Feeding for optimal production in goat and sheep
![Page 360: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/360.jpg)
360
Goat nutrition
The best management and health program is accentuated with a nutritional program that matches nutrient needs to production purposes
Goats are ruminants, which means they can derive a substantial portion of nutrients from plants
![Page 361: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/361.jpg)
361
Goat nutrition
Goats are selective browsers, eating a wide variety of shrubs, woody plants, briars and even weeds.
The availability of browse material in goat pens appears to enhance contentment.
![Page 362: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/362.jpg)
362
Goat nutrition
Goats should be fed good-quality forages along with the needed supplemental nutrients to achieve desired goals such as milk or meat production or a well-conditioned show goat.
![Page 363: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/363.jpg)
363
Goat nutrition
The nutritional program is dependent on type of goats (meat, milk, mohair/cashmere, hobby) and production stage.
Due to milk production needs, lactating dairy goats have higher nutrient requirements than dry or gestating does.
![Page 364: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/364.jpg)
364
Goat nutrition : forage
Hay and/or pasture (good-quality) can be used to provide primarily energy and some protein.
Since the goat is a ruminant, it needs to consume fiber (forage) in the form of hay or pasture or browse to maintain rumen health.
![Page 365: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/365.jpg)
365
Goat nutrition : forage
For dairy goats, fiber is needed to maintain milk fat test.
Rarely, if ever, will forage alone provide all nutrients needed by the goat.
The need for supplemental feeding will be dictated by the type of goat (meat, milk, mohair/cashmere, hobby) and production stage
![Page 366: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/366.jpg)
366
Goat nutrition : water
The dairy water requirement of goats is affected by level of milk production, environmental temperature, water content of feedstuff consumed, amount of exercise, and salt/mineral content of the diet.
![Page 367: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/367.jpg)
367
Goat nutrition : water
Fresh, clean water should be available at all time.
Goats are often more reluctant than other species to drink foul-tasting water.
Low-quality and/or inadequate water supply will reduce feed intake and lower goat performance.
![Page 368: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/368.jpg)
368
Goat nutrition : protein
Protein supplies amino acids for protein synthesis and serves as a source of nitrogen for rumen microorganisms.
Inadequate amount of protein in the diet can affect growth rate, milk production, reproduction, and disease resistance.
![Page 369: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/369.jpg)
369
Goat nutrition : protein
The amount of protein needed varies depending on production stage.
Young, fast-growing goats need a high level of protein in the diet to deposit muscle mass, and lactating goats need more protein for milk production.
![Page 370: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/370.jpg)
370
Goat nutrition : protein
Mature goats can effectively utilize non-protein nitrogen (NPN)
Rumen microorganisms need protein to effectively utilize forage.
Inadequate protein leads to inefficient utilization of forages and reduces forage intake.
![Page 371: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/371.jpg)
371
Goat nutrition : energy
Energy deficiency in goats reduces growth rate, delays puberty, reduces fertility and depresses milk production.
Fiber, starch, and sugar from forages and grains are the primary sources of energy in goat diets.
![Page 372: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/372.jpg)
372
Goat nutrition : energy
Fat can also be used to supply energy, but should be limited to no more than 5% of the diet.
Energy requirements are affected by body size, growth, reproduction, and lactation.
![Page 373: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/373.jpg)
373
Goat nutrition : energy
A deficiency of energy will result in loss of body condition, poor growth, reduced milking ability and reduced reproductive performance.
Obviously, goats that consume more energy than needed become fat.
![Page 374: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/374.jpg)
374
Goat nutrition : minerals and vitamins
Proper mineral and vitamin supplementation make it possible for goats to achieve the most economical gains possible from the forages and grain fed.
Minerals are needed in very small quantities, yet are critical components of overall nutritional package fed to goats.
![Page 375: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/375.jpg)
375
Goat nutrition : minerals and vitamins
Minerals play a vital role in nutrition digestion, reproductive performance, immune system function, and development of muscle, bone and teeth.
![Page 376: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/376.jpg)
376
Goat nutrition : minerals and vitamins
Vitamins are needed in small quantities for normal body processes.
Vitamins A, D and E are likely to be the most deficient in the normal diets of goats.
Vitamin K and the B-complex vitamins are normally synthesized by rumen microbes and are not considered essential for goats.
![Page 377: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/377.jpg)
377
Goat nutrition : minerals and vitamins
A diet consisting of forage, even with added grain, will not provide the proper levels of minerals and vitamins for optimal performance or production.
The amounts and ratios of certain minerals are also important in promoting the health and productivity of goats.
![Page 378: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/378.jpg)
378
Goat nutrition : minerals and vitamins
Due to the rumen microbial population, a synergistic effect on digestive efficiency occurs when protein and minerals are provided to ruminants
![Page 379: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/379.jpg)
379
Nutritional requirement of goatsGoats Percent protein
(CP)Percent energy
(TDN)
Bucks 11 60
Dry doe 10 55
Late gestation 11 60
LactationAvg. milkHigh milk
1114
6065
Weanling 14 68
Yearling 12 65
![Page 380: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/380.jpg)
380
Alpine (French) : Dairy goat Saanan : Dairy goat
Toggenburg : Dairy goat
![Page 381: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/381.jpg)
381
Angora : Fiber goat
Boer : meat goat
![Page 382: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/382.jpg)
382
Sheep nutrition
Feed represents the largest single costs in all types of sheep production.
Ration must be formulated to support optimum production, must be efficient and economical to feed, and must minimize the potential for nutrition-related problems.
![Page 383: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/383.jpg)
383
Sheep nutrition
A producer must know the animals’nutritional requirements during the different phrases of production, the nutrient composition of available feedstuffs, and how to provide the available feedstuffs to meet animals requirements.
![Page 384: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/384.jpg)
384
Sheep nutrition : nutrition of the ewe
A ewe’s nutritional needs are not static; they vary largely with her stage of production. For 16 to 20 wk of the year, the ewe’s energy needs are very critical (such as during breeding, immediately before lambing, and while lactating).
![Page 385: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/385.jpg)
385
Sheep nutrition : nutrition of the ewe
Feed levels can be lowered to reduce the feed cost during the early stages of gestation and when ewes are dry.
![Page 386: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/386.jpg)
386
Sheep nutrition : nutrition of the ewe
Maintenance of the ewe is generally thought of in terms of her nutritional requirement when dry, because at that time her requirements are the lowest of the year. However, wool production is a continuous process that must be considered as part of the nutrient requirements throughout the year.
![Page 387: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/387.jpg)
387
Sheep nutrition : nutrition of the ewe
The energy requirements are a function of the animals’ basic metabolic rate. However, several factors affect maintenance requirements
AgeExerciseClimateBody conditionReproductive requirementFlushing
![Page 388: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/388.jpg)
388
Sheep nutrition : nutrition of the ewe
AgeYearling tend to have about a 20% higher energy requirement than adult sheep. This is probably due to the yearlings’ additional requirements to support growth. This is of particular importance to producers who breed ewes to lamb first at 12 to 18 months of ages.
![Page 389: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/389.jpg)
389
Sheep nutrition : nutrition of the ewe
ExerciseGrazing sheep may use from 10 to 100% more energy than do sheep in drylotconditions.
ClimateTemperature, wind velocity, and humidity can jointly affect energy requirements. The length and density of the fleece also affects energy requirements
![Page 390: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/390.jpg)
390
Sheep nutrition : nutrition of the ewe
Body conditionIt takes more feed to maintain a fat sheep at a constant weight than it does a thin sheep.
Keeping the sheep excessively fat is not only expensive because of the feed, but also it is determined to the ewe’s reproductive capabilities and overall production efficiency.
A ewe should lose 5 to 7% of her BW during lactation and recover this weight loss during the dry period.
![Page 391: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/391.jpg)
391
Sheep nutrition : nutrition of the ewe
Reproductive requirementsReproductive efficiency depends largely upon proper nutrition before and during the breeding season.
Large-bodies ewes tend to produce more lambs per ewe.
Usually excessive fat ewes have lower conception rate and higher embryonic mortality.
![Page 392: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/392.jpg)
392
Sheep nutrition : nutrition of the ewe
Flushing Flushing can improve the ewe’s body condition just before and during the breeding season.
Generally, the practice is thought to increase ovulation rate.
Flushing has more effect early in the breeding season.
![Page 393: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/393.jpg)
393
Sheep nutrition : nutrition of the ewe
Flushing may be achieved by moving the ewes to a better pasture shortly before breeding.
The length of flushing period can vary, but it probably should begin 21 d before the breeding season and continue through one estrous cycle (17d) into the breeding season if possible.
![Page 394: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/394.jpg)
394
Sheep nutrition : requirements during gestation
During early gestation, a ewe’s nutrient requirements are only slightly higher than they are for maintenance.
Ewes in good condition at the end of the breeding period can loose some weight without hindering normal production.
![Page 395: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/395.jpg)
395
Sheep nutrition : requirements during gestation
If the weight loss is entirely recovered before breeding, lack of gain for the first 60 to 90 days of gestation should not have a negative affect on subsequent production.
![Page 396: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/396.jpg)
396
Sheep nutrition : requirements during gestation
The last 6 wk of gestation is the most critical period in ewe nutrition. Approximately 70% of the fetal growth occurs at this time.
Nutrient restrictions during this period may result in lighter lambs at birth, increased postnatal lamb losses, lower levels of milk production, and possibly pregnancy diseases.
![Page 397: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/397.jpg)
397
Sheep nutrition : requirements during gestation
In late pregnancy, ewes require about 50% more feed than they do earlier in gestation. If protein is limited during late gestation, lower birth rates and lighter ewe fleece weights can be expected.
Very often inadequate phosphorus intake occurs during this period, especially with ewes on pasture or with ewes consuming hay.
![Page 398: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/398.jpg)
398
Sheep nutrition : requirements during gestation
Ewes in late pregnancy sometimes have difficult consuming enough feed because of the space occupied by the fetus, particularly when they have twins or triplets.
![Page 399: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/399.jpg)
399
Sheep nutrition : requirements during gestation
If the ewe is fed a high-roughage ration, she may not be able to consume enough to supply the necessary daily energy requirements. For ewes in late pregnancy consuming high roughage rations, it is generally advisable to feed supplemental grain.
![Page 400: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/400.jpg)
400
Sheep nutrition : requirements during lactation
During the first few weeks following lambing, a lactating ewe requires about the same feed as in late gestation, provided she is nursing a single lamb.
If the lamb does not consume all the milk produced daily, the ewe produces less milk and uses any excess energy to store fat.
![Page 401: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/401.jpg)
401
Sheep nutrition : requirements during lactation
Ewes suckling twin lambs normally do not deposit fat because the nutrient supply (primary energy) does not meet the requirements of the lactating ewe. For maximum rate and efficiency of lamb gains, separate ewes nursing twin lambs from those nursing singles and feed accordingly.
![Page 402: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/402.jpg)
402
Sheep nutrition : requirements during lactation
It is practically impossible to provide high-producing ewes nursing twin lambs enough feed during lactation to prevent loss of body weight.
From a practical standpoint, these ewes must have reserves of body fat to maintain high levels of milk production. It is imperative that high-producing ewes are of acceptable body condition prior to lambing.
![Page 403: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/403.jpg)
403
Dorper : Meat sheep Southdown : Meat sheep
![Page 404: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/404.jpg)
404
Dalaine Merino : Wool sheep
Bluefaced Leicester : Wool sheep
Shetland : Wool sheep
![Page 405: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/405.jpg)
405
East Friesian : Dairy sheep
![Page 406: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/406.jpg)
406
Feeding horse for optimal health
![Page 407: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/407.jpg)
407
![Page 408: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/408.jpg)
408
![Page 409: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/409.jpg)
409
![Page 410: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/410.jpg)
410
![Page 411: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/411.jpg)
411
Performance horse nutrition
nutrients : energy sourcesHardworking horse needs more energy than the average horse on pasture.
Carbohydrates and fats are the most concentrated and efficient sources of calories for horses.Fibers is the safest sources.
![Page 412: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/412.jpg)
412
Performance horse nutrition
Nutrients : energy sourcesSubstances used directly in energy pathways are : glycogen and glucose from carbohydrate or amino acid metabolism, long chain fatty acids and glycerol for lipid metabolism, and volatile fatty acids from large intestine fermentation of fiber and carbohydrates.
![Page 413: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/413.jpg)
413
Performance horse nutrition
Nutrients :energy sourcesThe energy pathways utilized are either aerobic (requiring the presence of oxygen) or anaerobic (utilizing no oxygen).
Fuels and by products for aerobic and anaerobic work differ.
Aerobic sources of energy include long-chain fatty acids, volatile fatty acids, and glucose.
![Page 414: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/414.jpg)
414
Performance horse nutrition
Nutrients : energy sources.Metabolic by-products of aerobic metabolism are primarily carbon dioxide, water, and variable amounts of heat.
Only glucose and glycogen are utilized in anaerobic work, which generates heat and lactic acid as the major by-products.
Diet influences the energy sources utilized during work.
![Page 415: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/415.jpg)
415
Performance horse nutrition
Nutrients : energy sourcesMost feeds contain variable amounts of carbohydrate, fat and fiber.
The choice of diet should be based on the type of performance expected of the horse and availability and economics of feeds available.
Nutrients emphasized depend on the percent aerobic versus anaerobic work expected of the horse.
![Page 416: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/416.jpg)
416
Examples of type of work, body type, and primary energy sources theoretically utilized by performance horses
Type of competition
Primary type of work
Body type Primary energy sources
Flat racing Anaerobic (speed) Lean, minimal fat
Glycogen, glucose
Harness racing Anaerobic, aerobic (speed, stamina)
Lean, some fat reserves
Glycogen, glucose (fat, VFA)
Showing, jumping, steeplechase, rodeo, polo
Anaerobic, aerobic (speed, strength, stamina)
Muscular, moderate fat reserves
Glycogen, glucose, fat, VFA
3-day event, dressage, distance riding
Aerobic, anaerobic (stamina, some strength, speed)
Lean, muscular but adequate fat reserves
Fat, VFA (glycogen, glucose)
![Page 417: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/417.jpg)
417
Protein
Absolute need for protein is slightly increased in the hardworking horse.
Percent of protein in the diet need not be above maintenance (8–12%).
Horse will be eating more to meet its energy needs and thereby taking in more protein.
![Page 418: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/418.jpg)
418
Protein
Commonly used feeds that are high (above 14%) in protein include alfalfa, clover, soybean meal, and brewer’s grains.
![Page 419: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/419.jpg)
419
Electrolytes and water
The important electrolytes are potassium, sodium, chloride, magnesium and calcium.
If the horse sweats for a prolonged period of time during training or competition, it will need to ingest more water and electrolytes than normal to replace its losses.
![Page 420: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/420.jpg)
420
Electrolytes and water
Grasses and legumes are high in potassium. Legumes are also high in calcium and magnesium.
Most grains are deficient in all of the major electrolytes.
Both grains and hays have low levels of sodium.
![Page 421: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/421.jpg)
421
Electrolytes and water
Performance horses should have free access to sodium chloride.
Additional electrolytes are not usually necessary except after prolonged sweating (more than one hour) during training or competition.
![Page 422: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/422.jpg)
422
Electrolytes and water
Water requirements are not adequate met by any horse fed.
A separate source of clean, ice-free water is necessary for optimal performance.
A horse fed only dry hay and grain needs more water than a horse on lush pasture.
![Page 423: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/423.jpg)
423
Electrolytes and water
Water consumption may increase to as high as 30 to 40 L/day in hardworking horses.
The only time water intake should be restricted is if the animal is very hot, the water is very cold, or the horse is not going to continue to work after drinking
![Page 424: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/424.jpg)
424
Electrolytes and water
Under these circumstances the horse should be offered 2 to 3 L of water every 15 to 30 min until it is no longer thirsty or it is completely cooled.
![Page 425: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/425.jpg)
425
Electrolytes and water
Under conditions of prolonged sweating, such as endurance races or 2 to 3 h of intense training ,significant amount of water and electrolytes are lost.
If not replaced by allowing the horse to drink, graze, or consume 60 to 90 g of electrolytes supplement every 2 to 3 h, severe losses may result, necessitating intravenous therapy.
![Page 426: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/426.jpg)
426
Vitamins and minerals
Stress and high energy expenditure increase the levels of B vitamin and possibly ascorbic acid and vitamin E required in an athlete’s diet.
Fresh grass, alfalfa, and grass hays contain moderate to high levels of vitamins A, D, E, and B-complex.
![Page 427: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/427.jpg)
427
Vitamins and minerals
There are a multitude of vitamin-mineral supplements on the market, and the levels must be read carefully.
Trace mineral needs (i.e., copper, iron, zinc and iodine) are not known to be increased by exercise.
Supplementation of these may interfere with absorption and metabolism of other minerals.
![Page 428: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/428.jpg)
428
Nutritional and feed-induced diseases in horse
Metabolic disorders with multiple etiologies.
ColicLaminitisHyperlipemia and hyperlipidemiaAzoturia and rhabdomyolysis
![Page 429: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/429.jpg)
429
Classification of colics in horses
Potential causes
Category Nutritional Other
Gastric impactionHigh intake of cracked corn
or foreign objectslow-digestibility feed
Poor dentation
Parasitic damage to the gut
Large intestine impaction
Large amounts of pelletedfeed
Sudden switch from low fiber to high fiber diet
Inadequate waterIngestion of foreign
materials or sand
![Page 430: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/430.jpg)
430
Classification of colics in horses
Potential causes
Category Nutritional Other
Obstruction Enterolithiasis
ParasitismTorsionIncarceration
of bowel
SpasmodicHigh-concentrate diet with
altered motility in gastrointestinal system
stressAltered gut
motility
Sand Ingestion of sand
Parasitic
Parasitic damage to bowel wall or gut circulation
![Page 431: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/431.jpg)
431
Dietary recommendations for clinically ill horse
Clinical problem Nutritional objectives
Trauma, sepsis, burns Increased protein, energy, vitamins B, C, and E
Chronic diarrhea Increased water and electrolytes
Renal failureIncreased water and saltDecreased protein, calcium and
phosphorus
Hepatic disease Increased simple sugars, B vitamins, and short-branched-chain amino acids
![Page 432: Bioenergetics : basic concepts and ration formulationlas.vet.kps.ku.ac.th/LCS_2006.pdf · 11 Topics Basic concepts and ration formulation Protein nutrition and nonprotein nitrogen](https://reader031.fdocuments.net/reader031/viewer/2022013006/5ac0b0117f8b9a213f8c46dd/html5/thumbnails/432.jpg)
432
“....... มหาวิทยาลัย มุงมั่นสั่งสอนนกัศึกษาใหเปนคนเกง ซึ่งเปนการดี แตนอกจากจะสอนใหเกงแลวจําเปนอยางยิ่ง ที่จะอบรมใหดีพรอมกันไปดวย ประเทศเราจึงจะไดคนทีม่ีคุณภาพพรอมคอื ทั้งเกงและทั้งดีมาเปนกําลังของบานเมือง .......”
พระบรมราโชวาท พระราชทานแกคณะผูบริหารและสภาคณาจารยมหาวิทยาลัยตางๆ
ณ ศาลาดุสิดาลัย 3 ตุลาคม 2533