Avida “Reassignment of instruction sets using digital evolution.”

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AVIDA “REASSIGNMENT OF INSTRUCTION SETS USING DIGITAL EVOLUTION.” Bianca Bullock Scott Harrison Alex Ropelewski Bienvenido Velez

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Avida “Reassignment of instruction sets using digital evolution.”. Bianca Bullock Scott Harrison Alex Ropelewski Bienvenido Velez. Software Engineering. Original. Modifying the source code of the software How to control the code in other directions?. 1000 generations. - PowerPoint PPT Presentation

Transcript of Avida “Reassignment of instruction sets using digital evolution.”

Page 1: Avida “Reassignment of instruction sets using digital evolution.”

AVIDA“REASSIGNMENT OF INSTRUCTION SETS USING DIGITAL EVOLUTION.”

Bianca BullockScott Harrison

Alex Ropelewski

Bienvenido Velez

Page 2: Avida “Reassignment of instruction sets using digital evolution.”

SOFTWARE ENGINEERING Modifying the source code of the software How to control the code in other directions?

Original

1000 generations

Clone 1001-2000

S.P.1001-2000

CODON REASSINGMENT Which codes are we trying to modify? What is IOIO

AUG|GUG|UGA UAA UAG

Stop codons

Mukai, T., Hayashi, A., Iraha, F., Sato, A., Ohtake, K., Yokoyama, S., & Sakamoto, K. (2010). Codon reassignment in the Escherichia coli genetic code. Nucleic acids research, 38(22), 8188-8195.http://nar.oxfordjournals.org/content/38/22/8188.full

Page 3: Avida “Reassignment of instruction sets using digital evolution.”

HOW DO WE MONITOR AND SUPERCOMPUTE AVIDA EVOLUTION?

Which AVIDA organism is better and why? What happened and when?

Ancestor organismOrganism fromgeneration 483

Page 4: Avida “Reassignment of instruction sets using digital evolution.”

RUNNING AVIDA

Blacklight Writing a recursive script Parallel instead of serial processing of

multiple replicate Avida experiments

Page 5: Avida “Reassignment of instruction sets using digital evolution.”

ALTERING AVIDA

What is the purpose of altering the Avida source code?

What is the purpose of identifying the phenotype of an organism?

Why are we minimizing runtime?

Page 6: Avida “Reassignment of instruction sets using digital evolution.”

ACKNOWLEDGEMENTS

Pat Sudac (PSC) Alex Ropelewski (PSC) Pallavi Ishwad (PSC) Luis Vázquez-Quiñones (PSC) Hugh Nicholas (PSC) Scott Harrison (NCAT) Robert Newman (NCAT) Bienvenido Velez (UPRM)