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For over 30 years, Avantor™ Performance Materials, Inc. has been producing a full range of J.T.Baker® high-purity acetonitrile products that set the standard for high-sensitivity, accurate, reproducible, and high resolution analytical separations. Avantor has combined its expertise in the areas of purifi cation, packaging, and analytical testing to produce multiple grades of acetonitrile that have been application optimized and function-tested to meet the specifi c requirements of our customers. So whether you are doing routine, high-performance liquid chromatography, regardless of scale or advanced research, Avantor has a grade of J.T.Baker® brand acetonitrile to meet your needs.

ULTRA LC/MS™—9853

Bene� ts:

• Sustainable low trace metals resulting in minimal adduct formation

• Advanced suitability testing with both electrospray positive and negative modes

• Filtered through 0.1 µm fi lters to extend column life

• Low ion suppression enabling maximum sensitivity

Target Applications:

• Trace concentration in complex matrices using mass spectrometers

– Pharmacokinetics, clinical research

– Metabolomics, genomics, and proteomics

– Environmental (EPA Methods: 535 and 1694)

• Electrospray Ionization (ESI+, and ESI-)

• Nano-electrospray (Nanospray)

• Atmospheric Pressure chemical Ionization (APcI+ and APcI-)

• Instruments

– UHPLC (Ultra High Pressure Liquid Chromatography)

– Quadrupoles

– Ion trap

– Time of fl ight

– FT-ICR (Fourier transform ion cyclotron resonance mass spectrometer)

– MS-MS hybrids

• Drug discovery and development

• Instrument development, calibration, and validation

Acetonitrile: J.T.Baker® HPLC and LC/MS Analyzed Reagent

ProductLineOverview

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LC/MS—9821

Bene� ts:

• Function tested for LC/UV and LC/MS use

• Filtered through 0.2 µm fi lters to reduce particles

• Trace metal testing in ppb range to reduce interference

• Stringent UV specifi cations for improved sensitivity

Target Applications:

• Routine, well characterized analysis using mass spectrometers

– EPA Method 535*

– Toxicology, forensics, clinical assays

– Food and beverage safety testing

• Atmospheric Pressure chemical Ionization (APcI+)

• Electrospray Ionization (ESI+)

• Evaporative light scattering detection

– Low fl ow nebulizer (0.05–0.50 mL/minute)

• Drug identifi cation and degradation

• University research (non metabolomic applications)* EPA Method 535—Measurement of Chloroacetanilide and other Acetamide Herbicide Degradates in Drinking Water by Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry.

HPLC Ultra Gradient—9017

Bene� ts:

• Stringent gradient elution tests with UV/Vis and fl uorescence detection

• Interference-free, low baseline noise at 210 nm and 254 nm

• Tested for Polycyclic Aromatic Hydrocarbons (PAH)

• Tested for formaldehyde and other carbonyls

• Meets Chromatography Reagent Specifi cation for testing Ph. Eur. monographs.

Target Applications:

• Universal suitability for liquid chromatography

– Gradient liquid chromatography

– UHPLC (Ultra High Pressure Liquid Chromatography)

• Trace concentration analysis using UV/Vis and Fluorescence detection

– Photo diode array

– New product development

– Stability testing

– Impurity profi ling

– (U)HPLC method development

– Therapeutic drug monitoring

– High throughput analysis

• Evaporative light scattering detection

– High fl ow nebulizer (0.30–3.0 mL/minute)

• Environmental analysis

– Aldehydes and ketones testing (EPA method: 8315A**)

– Polycyclic Aromatic Hydrocarbons (PAH) testing (EPA methods: 550, 610,& 8310**)

** EPA Method 8315A—Determination of Carbonyl Compounds by High Performance Liquid Chromatography (HPLC) EPA Method 550—Determination of Polycyclic Aromatic Hydrocarbons in Drinking Water by b Liquid-Liquid Extraction and HPLC with Coupled Ultraviolet and Fluorescence Detection. EPA Method 610 and 8310—Polynuclear Aromatic Hydrocarbons

HPLC Gradient—9012

Bene� ts:

• Gradient elution tested at 254 nm

• Consistent, lot-to-lot uniformity

• Meets ACS specifi cations for HPLC suitability

Target Applications:

• Spectrophotometry

• Isocratic HPLC

• Routine, gradient analysis

• Refractive index detection

• Conductivity detection (ion chromatography)

• Preparative liquid chromatography

– Biopharmaceutical purifi cation

• UV/Vis detection

– Compounds containing a chromophore with an absorption maximum from 250–280 nm

– Variable wavelength

– Diode array

• Quality control

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Selection Guide

HPLC Gradient9012

HPLC Ultra Gradient 9017

LC/MS9821

ULTRA LC/MS9853

Key Speci� cations:

Gradient Elution (a.u. max.)

210 nm 0.002 0.002 0.002

254 nm 0.001 0.0005 0.0005 0.0005

UV/Vis Detection (a.u. max.)

190 nm (cut-off ) 1.00 1.00

220 nm 0.03 0.01

254 nm 0.01

400 nm 0.01 0.01

Particle Filtration (µm max.) 0.2 0.2 0.2 0.1

Residue After Evaporation (ppm max.) 5 1 0.8 0.8

Water Content (ppm max.) 200 100 100 100

Metal Ions (ppb max.) 50 25 (Na 50)

Polycyclic Aromatic Hydrocarbons (ppb max.) 0.5

LC Detector

Fluorescence NR ++ + +

UV/Vis + ++ + +

Refractive Index + ++ + +

Evaporative Light Scattering + + + ++

Mass Spectrometry Analyzer

Single Quadrupole NR NR + ++

Triple Quadrupole NR NR + ++

Ion Trap NR NR + ++

Time of Flight NR NR NR ++

MS-MS Hybrids NR NR NR ++

FT-ICR (Fourier transform ion cyclotron resonance mass spectrometer) NR NR NR ++

NR - Not Recommended + Suitable++ Ideal

For Product Information and Information on LC/MS Customer Dedicated Products feel free to contact us through our Customer Service at +31-570687500 or through our website at www.avantormaterials.com

Ordering Information and AssistanceCustomer ServiceTEL: +31-570-687500FAX: +31-570-687574 E-MAIL : avantor.emea@avantormaterials.com www.avantormaterials.com

AskAvantor™Our Web site features ASK Avantor,™ which includes live chat capabilities with customer service representatives. www.avantormaterials.com/askavantor

Corporate HeadquartersAvantor Performance Materials, Inc. 3477 Corporate Parkway Suite #200 Center Valley, PA 18034 USA

About Avantor™ Performance MaterialsAvantor Performance Materials manufactures and markets high-performance chemistries and materials around the world under several respected brand names, including the J.T.Baker®, Macron Fine Chemicals™, Rankem™, Diagnova™, BeneSphera™, and POCH™ brands.

Avantor products are used in a wide range of industries. Our biomedical and life science solutions are used in academic, industry and quality control laboratories for research, pharmaceutical production and medical lab testing, while our electronics solutions are used in the manufacturing of semiconductors and flat panel displays. Based in Center Valley, Pennsylvania (USA), Avantor is owned by an affiliate of New Mountain Capital, LLC.

For additional information please visit www.avantormaterials.com or follow www.twitter.com/avantor_news

Lit Number: 9014 ©2012 Avantor Performance Materials, Inc. All rights reserved. Trademarks are owned by Avantor Performance Materials, Inc. or its affiliates unless otherwise noted.

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