Automated Metered Dose Automated Metered Dose InhalerInhaler

Presented By Group 11:Presented By Group 11:Maria del Carmen CarrilloMaria del Carmen Carrillo

Jennifer B. StrubleJennifer B. StrubleLoyrirk TemiyakarnLoyrirk Temiyakarn

BackgroundBackgroundWhat is a Metered What is a Metered

Dose Inhaler?Dose Inhaler? pocket-sized handheld

inhaler delivers standardized

dose of medication for bronchodilation

Who Uses Them?Who Uses Them? Patients with asthma or

chronic obstructive pulmonary disease (COPD)

BackgroundBackground Setting?Setting?

Critical patients in hospitalsCritical patients in hospitals Prescriptions for outpatient Prescriptions for outpatient

or in-home useor in-home use How to Use?How to Use?

Shake InhalerShake Inhaler Hold up to mouthHold up to mouth Press down on the inhaler to Press down on the inhaler to

release the medicine as you release the medicine as you start to breathe in slowlystart to breathe in slowly

Hold breath for 10 secondsHold breath for 10 seconds Repeat if necessaryRepeat if necessary

Problem DefinitionProblem DefinitionAutomatic Metered Dose Inhalant (MDI) Automatic Metered Dose Inhalant (MDI)

delivery devicedelivery device: : Electromechanical, in-hospital inhalant Electromechanical, in-hospital inhalant

drug delivery systemdrug delivery system Patients are mechanically ventilated and Patients are mechanically ventilated and

sedatedsedated Medication delivered Medication delivered automaticallyautomatically as as

prescribed electronicallyprescribed electronically Medication must be well shaken Medication must be well shaken

(homogenized with propellant)(homogenized with propellant)

Design FactorsDesign Factors Integration with Integration with

existing existing endotracheal endotracheal tubingtubing

Homogenization Homogenization with propellantwith propellant

PressurizationPressurization SoftwareSoftware

User interfaceUser interface Prescription error Prescription error

checkingchecking

Project StatusProject Status

Preliminary Preliminary Research CompleteResearch Complete Standard MDIStandard MDI

Present ResearchPresent Research Endotracheal TubingEndotracheal Tubing

Proposed ResearchProposed Research VentilatorsVentilators HomogenizerHomogenizer

Working DesignWorking Design Integrated with existing Integrated with existing

tubingtubing T connectorT connector

Prefabricated MDI Prefabricated MDI canisterscanisters AerochamberAerochamber

Vortexer to homogenizeVortexer to homogenize Laptop based Laptop based

prescription entryprescription entry Similar to error reduction Similar to error reduction

system, Guardrails® system, Guardrails® Safety Software, in Alaris Safety Software, in Alaris “Smart” IV Pump“Smart” IV Pump

TimelineTimeline Completed WorkCompleted Work

Preliminary research Preliminary research Clearly defined Clearly defined

design factorsdesign factors Through Innovation Through Innovation

WorkbenchWorkbench Current WorkCurrent Work

Order components to Order components to start building start building prototypeprototype

Projected TimelineProjected Timeline Model A ~ End of JanuaryModel A ~ End of January

• Mechanical componentsMechanical components Testing ~ First week of Testing ~ First week of

FebruaryFebruary Implement correctionsImplement corrections

Model B ~ Second week Model B ~ Second week of Marchof March• Software includedSoftware included

Testing ~ End of MarchTesting ~ End of March Final prototype ~ AprilFinal prototype ~ April

ReferencesReferenceshttp://familydoctor.org/040.xmlhttp://familydoctor.org/040.xmlhttp://www.medlineplus.com/http://www.medlineplus.com/http://www.http://www.alarismedalarismed.com/.com/nana/press//press/

presskitpresskit__bkgdbkgd..shtmlshtmlhttp://www.drgreene.com/21_1377.htmlhttp://www.drgreene.com/21_1377.htmlhttp://www.med.umich.edu/anes/tcpub/ghttp://www.med.umich.edu/anes/tcpub/g

lossary/anesthesia_glossary-05.htmlossary/anesthesia_glossary-05.htm