Australian and New Zealand Intensive Care Research Centre ...

Australian and New ZealandIntensive Care Research Centre

Annual Report 2015

32

Director 3

About the ANZIC-RC 4

Aims 5

Governance 6

Staff 7

Students 8

Adjuncts 9

Visitors 10

Affiliates 11

Senior Research Fellows 12

Research Grants Active 13

NHMRC Funding Graphs 17

Awards 18

Publications 20

Publications Graph 25

Presentations 26

Conferences and Courses 35

Table of Contents Director

It is with great pleasure that I introduce the 2015 annual report of the ANZIC Research Centre.

The tenth year of the ANZIC-RC was marked by increasing research productivity and success. The Centre had 176 publications and major funding for exciting new collaborations. In 2015, the Centre was leading seven NHMRC-funded randomised controlled trials in intensive care medicine.

The NHMRC-funded EPO-TBI RCT (Erythropoietin in Traumatic Brain Injury) was presented at the ESICM Congress in Berlin in October 2015 and concurrently published in the Lancet. (Nichol et al. Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial. Lancet 2015.) The trial recruited 606 patients across sites in Australia, New Zealand, Saudi Arabia, Finland, France, Germany and Ireland), and for the first time found that a new therapy improved patient survival in TBI.

The Systemic Inflammatory Response Syndrome Criteria in Defining Severe Sepsis paper was published in the New England Journal of Medicine and concurrently presented at the ISICEM in Brussels in 2015 (Kaukonen KM, et al. NEJM 2015). Maija Kaukonen, first author on this paper, was a Senior Research Fellow at the ANZIC-RC from 2012 to 2013.

NHMRC funding ($4.4m) for the OPTIMISE-CAP study (Optimisation by Platform Trial Involving Multiple Interventions with Simultaneous Evaluation in Community Acquired Pneumonia) was approved.

In June 2015, the ANZIC-RC hosted the 2nd Collaborative Clinical Trials in Intensive Care Medicine Conference at Monash University’s Prato Centre in the elegant Salone Grollo of the Palazzo Vaj, Italy (near Florence), with invited attendees from more than 15 countries. The Prato conference provided a unique opportunity for participants to engage with internationally renowned leaders in intensive care medicine clinical trials.

We were delighted to have the Honourable Mike Rann, Australia’s Ambassador to Italy, San Marino, Albania and Libya, address the Conference. He spoke highly of the leadership demonstrated by the Australian Intensive Care Medicine group to strengthen the international collaborative networks for clinical trials, particularly with Europe.

I would like to thank our whole team of wonderful staff, adjuncts, students, affiliates and visiting researchers for their dedication to our Centre and its incredibly prolific research projects and programs.

Professor DJ (Jamie) CooperDirector ANZIC-RC

Celebrating

2006 - 2015

years

54

The Australian and New Zealand Intensive Care Research Centre (ANZIC-RC) is the National Health and Medical Research Council (NHMRC) and Monash University funded bi-national centre for development, coordination and execution of pivotal multicentre randomised controlled trials (RCTs) in critically ill patients. The outcomes of its research have changed medical care in Australia and internationally, improved patient outcomes and lowered health care costs. The parallel role of the ANZIC-RC is a national teaching centre for doctoral, postdoctoral and international clinician researchers in critical care medicine.

It was established in February 2006 within Monash University’s Department of Epidemiology and Preventive Medicine, based in the Alfred Medical Research and Education Precinct (AMREP) in Melbourne.

The ANZIC-RC offers a range of services, from research advice to complete project management. Advice and assistance is available from experienced intensive care unit (ICU) researchers, data management/bio-statistical consultants, project managers, epidemiologists and health economists. The Centre coordinates and conducts comprehensive research programs including observational studies; feasibility projects; and large multi-centred, interventional, randomised controlled trials. It has the ability to support small, medium and large clinical trials.

About the ANZIC-RC

The principal aims of the ANZIC-RC are to:

• Conduct high impact, large-scale,

investigator-initiated clinical trials designed

to determine best and most cost-effective

practice in Intensive Care Medicine (ICM)

• Increase the quality of clinical trial design

and biostatistical analysis in this field

• Be readily accessible to all Australian and

New Zealand clinician-researchers in critical

care

• Expand the national and international reach

of large Australian and New Zealand led

trials

• Introduce systems to integrate research

results into clinical practice by promulgating

research-based practice guidelines

• Develop integrated clinical research

programs that provide the training ground

for future clinical trialists in the field of ICM

• Encourage and support clinician researchers

in research theory, study design, study

conduct, data analysis and scientific writing

Aims

76

ANZIC-RC Governance - Advisory Board

Prof DJ (Jamie)

Cooper Director

ANZIC-RC

Prof Rinaldo Bellomo

Co-DirectorANZIC-RC and CICM

Representative

Prof John

McNeilHead

SPHPMMonash

A/Prof Andrew Turner

President ANZICS

Mr Peter

GallagherCommunity

Representative

A/Prof Erica

WoodTransfusion

Research Unit SPHPM, MonashRepresentative

A/Prof Colin

McArthurNew Zealand

Representative

Dr Carol

Hodgson ANZIC-RC

Post-Doctoral Research Fellow Representative

ANZIC-RC Staff

Dr Zoe

McQuiltenSenior

ResearchFellow

Ms Lisa

HigginsResearch

Fellow

Ms Emma Ridley

Nutrition Research

Fellow

Dr Carol

Hodgson Senior

Research Fellow

Prof Steve WebbInFACT

Representative

Prof David

PilcherChair

ANZICS-CORE

A/ProfCraig

FrenchChair

ANZICS-CTG

Dr Shay

McGuinnessNew Zealand

Representative

Ms Annie

SynnotCENTER-TBI

Research Fellow

MsBelinda Howe

Senior Project Manager:

SPICE Study

Ms Lorraine

LittleSenior Project

Manager: EPO-TBI and TARGET Studies

Ms Vanessa

SinghResearch and

AdministrationOfficer

Mr EdwardQuineData

Collection Assistant

Ms Peta

StellerData


Mr EdwardSaxbyData


Ms Tamzin

DimmockData


Ms Karin

AxelssonData


Ms Meredith

YoungProject

ManagerICU Recovery

Mr Tony

TrapaniProject

Manager POLAR Study

Ms Victoria BennettProject

Manager PHARLAP Study

Ms Bridget

Ady Project

Manager TRANSFUSE Study

Ms Genevieve

O’NeillProject

ManagerPandemics

Ms NatashaDodgeProject

ManagerPATCH (Acting)

Ms Veronica

PittProject

ManagerPATCH

Ms Siouxzy

Morrison Business Manager

Ms Amanda Martin

Administration Manager

Prof Alistair Nichol

Intensivist

A/Prof Michael Bailey

Statistician

Prof Kathy

Rowan ICU Research

A/Prof Andrew Davies

Consultant Research

Fellow

Ms Lynne

MurrayResearch and

Blood-CRE Manager

98

ANZIC-RC Students

Dr Helen

AcklandPhD

Conferred 2012

Dr Antoine

SchneiderPhD

Conferred 2015

A/Prof Daryl JonesPhD

Conferred 2015

DrRafidah

AtanPhD

Scholar

Dr AidanBurrell

PhD Scholar

DrDashiellGantner

PhD Scholar

Dr Neil

GlassfordPhD

Scholar

Ms Elizabeth

MoorePhD

Conferred 2014

Dr Lisen

HockingsPhD

Scholar

Ms Bianca

LevkovichPhD

Scholar

Dr Neil

OrfordPhD

Scholar

Ms EmmaRidleyPhD

Scholar

DrRavi

TiruvoipatiPhD

Scholar

DrNor’azim Mohd

YunosPhD

Scholar

Mr Simon Landes

BMedSc (Hons)Completed 2012

ANZIC-RC Adjuncts

ProfCécile

Aubron

Prof Tracey

Bucknall

Prof Gilles

Capellier

A/ProfMarianneChapman

Dr AnthonyDelaney

A/Prof DarylJones

Dr Peter

Kruger

A/ProfColin

McArthur

Dr Shay

McGuinness

A/ProfCristina

Morganti-Kossmann

ProfJohn

Myburgh

MsLynetteNewby

MsRachael

Parke

A/ProfSandraPeake

ProfVille

Pettilä

Prof David

Pilcher

A/Prof Jeff

Presneill

Mr EdwardQuine

BMedSc (Hons)Completed 2014

Ms Lisa

HigginsPhD

Scholar

A/Prof YaseenArabi

Mr Eldho PaulPhD

Scholar

A/Prof Glenn

Eastwood

Dr Andrew

Flint

Dr Samir

Haddad

MsSue

Huckson

ProfOlivierHuet

ProfJacques

Duranteau

Ms MadelineCenedese

BHlthSc (Hons)Completed 2015

Mr Ralph

TrammPhD

Scholar

1110

ANZIC-RC Adjuncts (continued)

Ms Shirley

Vallance

ProfSteveWebb

MsLeonie

Weisbrodt

ProfMichaelReade

MsElissa

Robins

DrMatthieuSchmidt

DrIan

Seppelt

ProfYahya

Shehabi

Mr Mick

Stephenson

MsTricia

Williams

MsJudyWills

DrGuillaume Carteaux(France)2010-1

ProfGilles

Capellier(France)2011-2

Dr Matthieu Schmidt (France)2013-4

Dr Aude

Garnero(France)2013-4

ProfKathy

Rowan(UK)2013

ANZIC-RC Visitors

ANZIC-RC Affiliates

DrHeatherWaddy

MsShaila

Chavan

DrMaija

Kaukonen

MsKerry

McClean

Dr Tài

Pham

ProfKathy

Rowan

Ms Allison

van Lint

Dr Aude

Garnero

A/Prof Theodore (Jack)

Iwashyna(USA)2015

Dr Kapil Dev

Soni

MsJane

Parker

A/Prof Andrew

Udy

1312

ANZIC-RC Senior Research Fellows

A/Prof DarylJones

(Australia)2006

Prof AlistairNichol

(Ireland)2007

DrAndrew

Westbrook(Ireland)

2008

Dr Cécile

Aubron(France)

2010

Dr Carol

Hodgson(Australia)

2011

ProfVille

Pettilä(Finland)

2009

Dr Maija

Kaukonen(Finland)2012-3

DrDashiellGantner

(Australia)2012

A/ProfAndrewDavies

(Australia)2014-5

Research Grants Active in 2015

Title Agency / Grant Type

Chief Investigator/s Year/s of Funding

Total Amount Administering Institution

Centre for Research in Intensive Care (DKK 36,000,000)

Danish Strategic Research Council

Perner A, Wetterslev J, Rasmus-sen B, Myburgh JA, Pettilӓ V, Egerød I, Kjellberg J, Bonde J, Gluud C, Bestle M, Bulow H-H, Winding R, Lange T, Nibro H, Møller M, Rowan K, Finfer S, Werneman J

2015-2020 $7,400,000 Copenhagen University

TARGET: The Augmented versus Routine approach to Giving Energy Trial

NHMRC #1078026Project Grant

Chapman M, Peake S, Bellomo R, Horowitz M, Davies A, Deane A

2015-2019 $3,534,236 Monash (ANZIC-RC)

NHMRC Practitioner Fellowship Level II NHMRC #1081884Practitioner Fellowship

Myburgh JA 2015-2019 $551,435 University of Sydney

SUDDICU: Cluster RCT of selective decontamination of the digestive tract in critically ill ventilated patients


Seppelt I, Myburgh JA, Finfer S, Iredell J, Davis J, Marshall A, Taylor C, Cuthbertson B

2015-2019 $3,960,000 University of Sydney

TREATT: Trial to evaluate anti-fibrinolytic therapy in thrombocytopenia


Wood E, Stanworth S, Cole-Sinclair M, Westerman D, Szer J, Estcourt L, McQuilten Z

2015-2019 $1,012,635 Monash

ADRENAL-GEPS: Gene expression profiling in critically ill patients with septic shock


Evans D, Venkatesh B, Powell J, Myburgh JA, Finfer S, Cohen J

2015-2019 $834,269 University of Queensland

OzENTER-TBI: Australian-European NeuroTrauma Effectiveness Research, Traumatic Brain Injury Collaboration - A Prospective Longitudinal Observation Study

TAC/ISCRRInstitute for Safety, Compensation and Recovery ResearchProject GrantN-14-129

Cooper DJ 2015-2018 $118,271 Monash(ANZIC-RC)

ASPREE-NEURO: Aspirin and cerebral microhaemorrhages


McNeil J, Egan G, Brodtmann A, Ward S, Ferris N, Bailey M

2015-2017 $956,186 Monash

Investigating the role of lysophosphatidic acid (LPA) in pediatric brain injury

NIH (R03)Project Grant

Lifshitz J, Morganti-Kossmann MC, et al

2015-2017 $110,000 University of Arizona

A research program testing feasibility and impact of early of fibrinogen concentrate therapy in adults with traumatic haemorrhage

Alfred Foundation (Borrowman Trust)

Cooper DJ 2015-2016 $24,850 Alfred

IS-HR-BAD: Ivabradine in sepsis for heart rate, benefits and disadvantages trial; an open-label phase II feasibility study

Alfred Research TrustsProject Grant#T11512

Rozen T, Udy A 2015-2016 $8,922 Alfred

Australian College of Nursing (ACN) Travel Award to EURO-ELSO International Congress in Regensburg, Germany

ACNTravel Grant

Tramm R 2015 $800 Monash (ANZIC-RC)

Australasian Epidemiological Association (AEA) Student Award

AEAAward

Tramm R 2015 $500 Monash(ANZIC-RC)

Alfred SMS Travel Scholarship. EURO-ELSO, Regensburg, Germany

AlfredTravel Grant

Burrell A 2015 $2,500 Alfred

1514

Research Grants Active in 2015 (continued) Research Grants Active in 2015 (continued)



Total Amount

Administering Institution

BEST-TBI: A prospective RCT of the use of bactericidal external ventricular drains in patients with traumatic brain injury

Alfred FoundationProject Grant

Moore J, Rosenfeld JV, Thomas P, Gantner D, Roodenburg O, Maartens N, Cheng A, Vallance S

2015 $21,560 Alfred

ICU Recovery: Critical illness and long-term recovery - motomed cycle ergometer with muscle stimulation

Alfred FoundationEquipment Grant

Hodgson C 2015 $25,000 Alfred

Validation of the “expert recommendations for safe mobilization of mechanically ventilated patients in ICU” – an observational study

Alfred FoundationProject Grant

Capell E, Tipping C, Hodgson C 2015 $9,800 Alfred

The Alfred Hospital Nursing Research Committee Award

Alfred Nursing Research Committee Award


Creation of automatic alerts to identify patients at risk of deterioration after discharge from ICU

Alfred Health Top 100 InnovationProject Grant

Ihle J, Scheinkestel C, Pilcher D, Larkins A, Mwagiru A, Schneider H, Bucknall T, Ng Y, Gilbert A

2015 $100,000 Alfred

Comparative safety of difference types of intravenous fluids for resuscitation in the operating room and the intensive care unit: an applied pharmaco-epidemiologic approach ($94,000)

Anesthesia Patient Safety Foundation (USA)Project Grant

Raghunathan K, Shaw A, Lindenauer P, Myburgh JA, Perner A

2015 $132,528 Duke University

HELP-ECMO: Heparin low dose protocol versus standard care in critically ill patients undergoing extracorporeal membrane oxygenation

ANZCAProject Grant

McIlroy D, Cooper DJ, Aubron C, Pilcher D, Pellegrino V

2015 $37,000 Alfred

Australasian Society for Traumatic Stress Studies (ASTSS), Second prize, Annual Award for Academic Excellence in Traumatic Stress Research

ASTSSAward


College of Intensive Care Medicine, Norva Dahlia Foundation Study Grant/Scholarship “Improving Extracorporeal membrane oxygenation research Definitions And ouTcome Measures: E-DATM Project” Research fellowship in Germany

CICMScholarship

Burrell A 2015 $5,000 Alfred

Outcome, predictive factors of survival and performance of the Survival After Venoarterial-ECMO (SAVE)-score for patients receiving ECMO to support CPR (E-CPR) (US$10,000)

Extracorporeal Life Support Organization (ELSO)Project Grant

Schmidt M, Pellegrino V, Bailey M, Pilcher D

2015 $14,063 Alfred

Pharmacokinetic Australasian Collaborative

ICFProject Grant

Lipman J, Roberts J, Peake SL, Joynt GM, Udy AA, Nicholls MB

2015 $39,156 University of Queensland

TxA levels in the PATCH-TRAUMA trial ICF Project Grant

Reade M 2015 $38,350 University of Queensland

A pilot, randomised, unblended feasibility, safety and biochemical and physiological efficacy study of 20% vs 4% human albumin solution for fluid bolus therapy in critically ill adults

Intensive Care Foundation Project Grant

Mårtensson J, Bellomo R, Eastwood GM, Bersten A, Bihari S

2015 $18,928 Austin Health

Postgraduate Research Scholarship Award (extension)

Monash University, Tramm R 2015 $13,000 Monash(ANZIC-RC)

Postgraduate Research Travel Grant Monash University, SPHPM Travel Grant

Tramm R 2015 $2,000 Monash(ANZIC-RC)

Travel Grant to attend Prato, Italy, and ECMO-NET, Paris

Monash University, SPHPM Travel Grant

Hodgson C 2015 $2,000 Monash(ANZIC-RC)



Total Amount

Administering Institution

Multimodal neuromonitoring in acute brain injury program

University of New South Wales: Major Research Equipment and Infrastructure Initiative Grant

Cheng A, Saxena M, Myburgh JA, Aneman A, Davies M

2015 $234,335 University of New South Wales

Improving outcomes in critical illness (€2,350,000)

Health Research Board, Ireland

Project Grant

Nichol A, Cooper DJ, Laffey J, McLoughlin P, Ryan T, McAuley D

2014-2019 $3,421,450 University College, Dublin

SPICE III: Early goal directed sedation in mechanically ventilated intensive care patients (NZ$1,118,620)

Health Research Council of NZ

Project Grant

McArthur C, Bellomo R, Henderson S, McGuinness S, Young P, Williams A, Freebairn R, Casement J, Shehabi Y

2014-2018 $1,061,170 Auckland District Health Board

TRANSFUSE-RCT: Standard issue transfusion versus fresher red blood cell use in intensive care

ARCBSCollaborative funding

Cooper DJ, McQuilten Z, Murray L

2014-2017 $300,000 Monash (ANZIC-RC)

Diggers to Veterans: risk, resilience and recovery in the First AIF

Australian Research Council Discovery Project

McCalman J, Kippen R, Reade MC, Shanks D, Hopper D

2014-2017 $560,000 University of Melbourne

Investigating the effects of the age of transfused red cells on haemolysis and iron metabolism in critically ill patients: a TRANSFUSE sub study

ARCBSCollaborative funding

McQuilten Z, Aubron C, Pasricha S-R, Sparrow R, Wood E, Flower R, Irving D

2014-2016 $72,000 Monash

OzENTER-TBI Australia-Europe NeuroTrauma Effectiveness Research in TBI collaboration

NHMRC #1074181EU Collaborative Research Grants

Cooper DJ, Gruen R 2014-2016 $358,348 Monash(ANZIC-RC)

MTR: Improving outcomes for patients with critical bleeding requiring massive transfusion

NHMRC #1074654Partnership Project

Cooper DJ, Wood E, Cameron P, Isbister J, French C, Stanworth S, McLintock MC, McQuilten Z, et al

2014-2016 $861,706 Monash(ANZIC-RC)

PREPARE: Platform for European Preparedness Against Re-emerging Epidemics-Australia

NHMRC #1074888EU Collaborative Research Grants

Webb SAR et al 2014-2016 $375,834 University of WA

NHMRC Postgraduate Scholarship NHMRC #1075288PostgraduateScholarship

Ridley E 2014-2016 $102,578 Monash(ANZIC-RC)

PHARLAP Substudy: Do ARDS patients with different subtypes behave differently?

ANZCA Project Grant

McGuinness S / Hodgson C, Bihari S, Bersten A, Nichol A

2014-2015 $34,950 Monash(ANZIC-RC)

CLEAN TBI: A prospective RCT of the use of bactericidal external ventricular drains in patients with traumatic brain injury

Brain FoundationProject Grant

Moore J, Rosenfeld JV, Thomas P, Gantner D, Roodenburg O, Maartens N, Cheng A

2014-2015 $17,000 Alfred

The epidemiology of pyroglutamic acidosis in a critically ill population

Royal Brisbane & Women’s Hospital Foundation Project Grant

Reade MC, Roberts J, Pretorius C, McWhinney B, Lipman J, Ungerer J


SPICE Sedation Practices in IntensiveCare Evaluation - RandomisedControlled Trial (RCT)


Shehabi Y, Bellomo R, Reade M,Seppelt I, McArthur C, Bailey M,Howe B

2013-2017 $2,752,725 Monash(ANZIC-RC)

NHMRC Practitioner FellowshipLevel II

NHMRC #1044787Practitioner Fellowship

Bellomo R 2013-2017 $228,270 Austin

1716

Research Grants Active in 2015 (continued) Research Grants Active in 2015 (continued)




NHMRC Practitioner Fellowship Level II NHMRC #1041922Practitioner Fellowship

Cooper DJ 2013-2017 $380,450 Monash (ANZIC-RC)

Supplemental Parenteral Nutrition in Critically Ill Patients: Pilot Randomised Controlled Study

Baxter Healthcare CorporationProject Grant

Davies A, Cooper DJ 2013-2016 $321,691 Monash (ANZIC-RC)

ANTISEPSIS: AspiriN To Inhibit SEPSIS trial

NHMRC #1041986 Project Grant

Eisen D, Leder K, McBryde E, Wolfe R, Pilcher D, et al

2013-2016 $391,879 Monash

RELIEF: Restrictive versus Liberal Fluid Therapy in Major Abdominal Surgery


Myles P, Bellomo R, ChristophiC, Corcoran T, Forbes A, Peyton P, Story D

2013-2016 $2,384,173 Monash

PATCH: Pre-hospital Antifibrinolytics for Traumatic Coagulopathy and Haemorrhage


Bernard S, Mitra B, Gruen R, Gantner D, Medcalf R, Reade M, Tran H (originally Gruen R, Mitra B, Bernard S, Jacobs I, Medcalf R, Reade M, Tran H)

2013-2016 $1,668,152 Monash

SMARTT: Sampling antibiotics in renal replacement therapy


Roberts J, Lipman J, Roberts M, Paul S, Peake S, Turnidge J

2013-2016 $1,034,979 University ofQueensland

Understanding tissue responses to fluid resuscitation and blood transfusion during ovine sepsis to improve outcomes


Fraser J, Maitland K, Shekar K, Reade MC, Chew M, Fung YL, Tung J

2013-2016 $1,000,000 Prince Charles Hospital Foundation

How effective is frozen blood in the treatment of severe trauma?

Defence Health Foundation Project Grant

Milford E, van Zyl N, Chew M, Tung JP, Shekar K, Fraser J, Reade MC

2013-2015 $85,000 Prince Charles Hospital Foundation

CENTER-TBI: Collaborative European NeuroTrauma Effectiveness Research in TBI (Total Grant €30m, Australian component €279,499)

European Union’s Seventh Framework Programme for Research (EU FP7)

Maas A, Menon D, Hill S, Steyerberg E, von Steinbüchel N, Brazinova A, Buki A, Tenovuo O, Van Hecke W, ... Cooper DJ, et al

2013-2015 $409,491 Monash(ANZIC-RC)

PREPARE: Platform for European Preparedness Against Re-emerging Epidemics (Total Grant €26m, Australian component €0)

European Union’s Seventh Framework Programme for Research (EU FP7)

Goosens H, Nichol A, Horby P, Butler C, Bonten M, deJong M, Ieven G, Leus F, Simonds A, Farrar J, Brown C, … Webb S

2013-2015 $0 University of Western Australia

BLING II: RCT of continuous vs inter-mittent beta-lactam antibiotics in the critically ill (NZ$213,894)


Project Grant

McArthur C, McGuinness S, Lipman J, Young P, Freebairn R, Dulhunty J, Williams A

2013-2015 $202,378 Auckland District Health Board

Blood-CRE: CRE for Patient Blood Management in Critical Illness and Trauma

NHMRC #1040971Centre of Research Excellence

Cooper DJ, Phillips L, Bellomo R, Cameron P, Reade M, Isbister J, French C, Myles P, Webb S, McNeill J

2012-2017 $2,498,407 Monash (ANZIC-RC)

ADRENAL: Randomised trial of hydrocor-tisone in critically ill patients with septic shock (NZ$773,854)


Project Grant

McArthur C, Venkatesh B, Young P, McGuinness S, Williams A, Freebairn R, Finfer S, Myburgh J, Henderson S


A pilot randomised, controlled, double-blind clinical trial of cryopreserved platelets

ANZCA Academic Enhancement Grant

Reade MC, Holley A, Irving D, Marks D, Johnson L, Fraser J, Bellomo R, Gattas D


CLIP: A pilot randomized, controlled, double-blind clinical trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of post-surgical bleeding

Australian Red Cross Blood Service Research Development Grant

Reade MC, Holley A, Irving D, Marks D, Johnson L, Fraser J, Bellomo R, Gattas D





INFORM: Informing Fresh versus Old Red Cell Management: A large simple phase III RCT

Canadian Institutes of Health Research (CIHR)Project Grant

Eikelboom J, Arnold D, Cooper DJ, Crowther M, Devereaux PJ, et al

2012-2015 $1,606,292 McMaster University (Canada)

TRANSFUSE: Standard issue transfusion versus fresher red blood cell use in inten-sive care (NZ$775,723)


Project Grant

McArthur C, Bellomo R, Young P, Cooper J, McGuinness S, Williams A, Freebairn R, Henderson S, Flanagan P


TRANSFUSE-RCT: Standard issue transfusion versus fresher red blood cell use in intensive care


Cooper DJ, Nichol AD, French C, Street A, Bellomo R

2012-2015 $2,761,870 Monash (ANZIC-RC)

PHARLAP-RCT: Multicentre RCT of open lung strategy including Permissive Hypercapnia, Alveolar Recruitment and Low Airway Pressure in patients with ARDS


Nichol AD, Davies AR, Hodgson CA, Bersten A, Fraser J, Cooper DJ

2012-2015 $997,538 Monash (ANZIC-RC)

NHMRC Early Career Research Fellowship: ICU management and quality of survival of ARDS

NHMRC #1035050Early Career Research Fellowship

Hodgson C 2012-2015 $294,892 Monash(ANZIC-RC)

Does age of the transfused blood matter in acutely ill patients with trauma and infection?

Queensland Emergency Medicine Research Foundation Project Grant

Staib A, Ashton K, Fraser JF, Fung YL, Shekar K, Chew M, Reade M, Tung JP, McDonald C

2012-2015 $200,000 Prince Charles Hospital Foundation

TBI Program: Early Interventions to improve outcomes after traumatic brain injury

TAC / VNI #D162Program Grant

Cooper DJ, Cameron P, Bernard S, Rosenfeld J, Nichol A

2010-2017 $2,086,100 Monash(ANZIC-RC)

ANZIC-RC: National Centre for Intensive Care Research - Renewal

NHMRC #606978Enabling Grant

Bellomo R, Cooper DJ, Myburgh J, Finfer S

2010-2015 $2,500,000 Monash (ANZIC-RC)

Total $51,818,040

NHMRC Funding Graphs (ANZIC-RC Administered Grants)

1918

Awards Awards (continued)

Congratulations to the ANZIC-RC staff, students and adjuncts who received awards in 2015, as follows:

• Michael Reade (Adjunct Professor): • Australian Defence Force Operational Service Medal with clasp “Greater Middle East Area of Operations”• Promoted to Colonel in the Australian Army• United States of America Army Commendation Medal for leadership during a critical incident whilst

deployed on war-like operations in support of the US-Australian coalition

• Mick Stephenson (Adjunct Research Fellow): Ambulance Service Medal Recipients Australia Day 2015 (ASM VIC) Australia Day honour for his distinguished service to Ambulance Victoria

• Rinaldo Bellomo (Professor and Co-Director): • The first ANZ biomedical researcher to have more than 1000 publications in Scopus• One of 11 Monash staff members named on the 2015 Thomson Reuters list of Highly Cited (HiCi)

Researchers, placing them among the top one per cent of the most highly cited researchers in the world within their subject area

• Fellowship of the Australian Academy of Health and Medical Sciences (FAAHMS)

• Jamie Cooper (Professor and Co-Director): Fellowship of the Australian Academy of Health and Medical Sciences (FAAHMS)

• John Myburgh (Adjunct Professor): • Peer Review Honour Roll, External Assessor Outstanding Contribution, National Health and Medical

Research Council• The George Institute for Global Health Impact Award• Fellowship of the Australian Academy of Health and Medical Sciences (FAAHMS)

• Andrew Udy (Adjunct A/Professor): Alfred Health Senior Medical Staff Prize for Clinical Research for “The Association Between Low Admission Peak Plasma Creatinine Concentration and In-Hospital Mortality in Patients Admitted to Intensive Care in Australia and New Zealand” co-contributors included Carlos Scheinkestel, David Pilcher, Michael Bailey, and the Australian and New Zealand Intensive Care Society Centre for Outcomes and Resource Evaluation

• Carol Hodgson (Senior Research Fellow): Monash University FMNHS ECR Fellows Publication Prize for “Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults”

• Alfred ICU (Emma Ridley) has again been named the ‘Best of Best’ in the International Nutrition Survey, out of 166 ICUs internationally. This means that against the Canadian Clinical Practice Guidelines for nutrition, the Alfred ICU nutrition practices have been judged the best

• Josh Ihle, Carlos Scheinkestel, David Pilcher (Adjunct Professor), Anne Larkins, Anne Mwagiru, Hans Schneider, Tracey Bucknall, Yen Ng, Annie Gilbert, ICU/IT prediction model proposal (Creation of automatic alerts to identify patients at risk of deterioration after discharge from the intensive care unit) was a winner in the Alfred Health Top 100 Leadership Innovation competition and received $100,000 to implement the plan

• Cristina Morganti-Kossmann (Adjunct A/Professor): Sabbatical 5 October - 3 November 2015 (Salary and travel funded by University of Arizona), Translational Neurotrauma Research Program, Barrow Neurological Institute, Department of Child Health, University of Arizona, Phoenix, AZ, USA Project 1: Role of Lysophosphatidic Acid (LPA) in pediatric TBI, Translating experimental to clinical research. Project 2: LPA in TBI: from biomarker to therapeutic target”

• Yen Hing Ng, David Pilcher, Chris Bain, Chris MacManus and Tracy Bucknall won the inaugural Alfred Health Greg Barclay Award for Nursing Research for “Predicting the need for medical emergency response in patients discharged from ICU at The Alfred Hospital”

• Skinner E, Iwashyna TJ, Higgins A, Hodgson C: ICF Inaugural Malcolm Fisher Award for grant “Next generation assessments of physical function in ICU survivors” ($35,000)

• Vanessa Singh (Research and Admin Officer): School of Public Health and Preventive Medicine, Monash University Quiet Achiever Award

• Emma Ridley (Nutrition Research Fellow and PhD Scholar): Women & Leadership Australia, Certificate of Completion of the Advanced Leadership Program

• Daryl Jones: PhD conferred, “The Rapid Response Team: Patient characteristics and resource implications”, Supervisors Rinaldo Bellomo and Graeme Hart

• Antoine Schneider: PhD conferred, “Renal Perfusion Evaluation with Contrast Enhanced Ultrasonography”, Supervisors Rinaldo Bellomo and Michael Bailey

• Zoe McQuilten (Senior Research Fellow): PhD conferred on the successful examination of her thesis “Improving patient outcomes through understanding and changing transfusion practice”, Supervisors John McNeil, Peter Cameron and Erica Wood

• Rachael Parke (Adjunct Senior Research Fellow): PhD conferred - One of the Top 5 PhD theses from University of Auckland, School of Nursing, Faculty of Medical and Health Sciences, Thesis on “High Flow Nasal Oxygen Therapy in Patients after Cardiac Surgery”

• Aidan Burrell (PhD Scholar): • College of Intensive Care Medicine, Norva Dahlia Foundation Study Grant/Scholarship, “Improving

Extracorporeal membrane oxygenation research Definitions And ouTcome Measures: E-DATM Project” Research fellowship in Germany. A Burrell V Pellegrino, J Cooper, D Kaye

• Alfred SMS Travel Scholarship, EuroELSO, Regensburg, Germany. Dr Aidan Burrell, Assoc Prof Vin Pellegrino, Prof David Kaye, Prof Jamie Cooper and Assoc Prof David Pilcher

• Bianca Levkovich (PhD Scholar): Fellowship of the Society of Hospital Pharmacists of Australia

• Neil Glassford (PhD Scholar): • NIHES/Erasmus Summer Programme (ESP) Fellowship 2015 in Clinical Research Training at Erasmus

University in Rotterdam• Inaugural appointee to the Academy of Health and Medical Sciences Mentoring Scheme (Mentor: Professor

Richard Larkins) and Associate of the Academy of Health and Medical Sciences

• Ralph Tramm (PhD Scholar): • Travel Award, Australian College of Nursing for Euro-ELSO, Regensburg, Germany• Postgraduate Research Travel Grant, Monash University• Postgraduate Research Scholarship Award (extension), Monash University• Nursing Research Committee Award, The Alfred Hospital• Student Award, Australasian Epidemiological Association (AEA) • Second prize, Annual Award for Academic Excellence in Traumatic Stress Research, Australasian Society

for Traumatic Stress Studies (ASTSS)

2120

Journal Publications 1. Ackland HM, Pilcher DV, Roodenburg OS, McLellan SA,

Cameron PA, Cooper DJ. Danger at every rung: Epidemiology and outcomes of ICU-admitted ladder-related trauma. Injury 2015;epub.

2. Ahmed B, Hanna J, Nichol A. Acute kidney injury and the critically ill. Anaesth Intensive Care Med 2015;16:186-90.

3. Alwis DS, Yan E, Johnstone V, Carron S, Hellewell S, Morganti-Kossmann C, Rajan R. Environmental Enrichment Attenuates Traumatic Brain Injury-Induced Neuronal Hyperexcitability in Supragranular Layers of Sensory Cortex. J Neurotrauma 2015;epub.

4. Angus D, Peake S, Rowan K. Early goal-directed therapy in the treatment of sepsis: response to comments by Jaehne et al. Intensive Care Med 2015;41:1729-30.

5. Angus DC, Barnato AE, Bell D, Bellomo R, Chong CR, Coats TJ, Davies A, Delaney A, Harrison DA, Holdgate A, Howe B, Huang DT, Iwashyna T, Kellum JA, Peake SL, Pike F, Reade MC, Rowan KM, Singer M, Webb SA, Weissfeld LA, Yealy DM, Young JD. A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators. Intensive Care Med 2015;41:1549-60.

6. Atan R, May C, Bailey SR, Tanudji M, Visvanathan K, Skinner N, Bellomo R, Goehl H, Storr M. Nucleosome levels and toll-like receptor expression during high cut-off haemofiltration: a pilot assessment. Crit Care Resusc 2015;17:239-43.

7. Aubron C, Suzuki S, Glassford NJ, Garcia-Alvarez M, Howden BP, Bellomo R. The epidemiology of bacteriuria and candiduria in critically ill patients. Epidemiol Infect 2015;143:653-62.

8. Bailey M, McGuinness S, Haase M, Haase-Fielitz A, Parke R, Hodgson CL, Forbes A, Bagshaw SM, Bellomo R. Sodium Bicarbonate and Renal Function after Cardiac Surgery: A Prospectively Planned Individual Patient Meta-analysis. Anesthesiology 2015;122:294-306.

9. Bannard-Smith J, Alexander P, Glassford N, Chan MJ, Lee M, Wong BT, Crawford G, Bailey M, Bellomo R. Haemodynamic and biochemical responses to fluid bolus therapy with human albumin solution, 4% versus 20%, in critically ill adults. Crit Care Resusc 2015;17:122-8.

10. Baptista JP, Udy AA. Augmented renal clearance in critical illness: “The Elephant in the ICU”? Minerva Anestesiol 2015;81:1050-2.

11. Barber EA, Everard T, Holland AE, Tipping C, Bradley SJ, Hodgson CL. Barriers and facilitators to early mobilisation in Intensive Care: A qualitative study. Aust Crit Care 2015;28:177-82.

12. Barlow CJ, Morrison S, Stephens HO, Jenkins E, Bailey MJ, Pilcher D. Unprofessional behaviour on social media by medical students. Med J Aust 2015;203:439.

13. Bell M, Larsson A, Venge P, Bellomo R, Martensson J. Assessment of cell-cycle arrest biomarkers to predict early and delayed acute kidney injury. Dis Markers 2015;2015:158658.

14. Bellomo R. Decade in review-acute kidney injury: Acute kidney injury-a decade of progress. Nat Rev Nephrol 2015;11:636-7.

15. Bellomo R, Kellum JA. Integration of acid-base and electrolyte disorders. N Engl J Med 2015;372:391.

16. Bellomo R, Marik P, Kellum JA. Lactic acidosis. N Engl J Med 2015;372:1076.

17. Bellomo R, Martensson J, Kaukonen KM, Lo S, Gallagher M, Cass A, Myburgh J, Finfer S. Epidemiology of RBC Transfusions in Patients With Severe Acute Kidney Injury: Analysis From the Randomized Evaluation of Normal Versus Augmented Level Study. Crit Care Med 2015;epub.

18. Bellomo R, Martensson J, Lo S, Kaukonen KM, Cass A, Gallagher M. Femoral Access and Delivery of Continuous Renal Replacement Therapy Dose. Blood Purif 2015;41:11-7.

19. Bellomo R, Martin A, Cooper DJ. The Australian and New Zealand Intensive Care Research Centre. Blood Purif 2015;41:I-IV.

20. Bihari S, Bailey M, Bersten AD. Steroids in ARDS: to be or not to be. Intensive Care Med 2015;epub.

21. Bihari S, Maiden M, Deane A, Fuchs R, Fraser J, Bersten AD, Bellomo R. Preclinical research in critical care - the Australasian perspective. Crit Care Resusc 2015;17:151-2.

22. Bihari S, Peake SL, Prakash S, Saxena M, Campbell V, Bersten A. Sodium balance, not fluid balance, is associated with respiratory dysfunction in mechanically ventilated patients: a prospective, multicentre study. Crit Care Resusc 2015;17:23-8.

23. Botha J, O’Brien Y, Malouf S, Cole E, Ansari ES, Green C, Tiruvoipati R. The Outcome and Predictors of Mortality in Patients Therapeutically Cooled Postcardiac Arrest. J Intensive Care Med 2015;epub.

24. Bove T, Landoni G, Bellomo R. Fenoldopam and acute kidney injury--reply. JAMA 2015;313:971.

25. Bragge P, Synnot A, Maas A, Menon D, Cooper DJ, Rosenfeld JV, Gruen RL. A State of the Science Overview of Randomised Controlled Trials evaluating Acute Management of Moderate to Severe Traumatic Brain Injury. J Neurotrauma 2015;epub.

26. Brazinova A, Rehorcikova V, Taylor MS, Buckova V, Majdan M, Psota M, Peeters W, Feigin V, Theadom A, Holkovic L, Synnot A. Epidemiology of traumatic brain injury in Europe: a living systematic review. J Neurotrauma 2015;epub.

27. Burrell A, Hayward C, Mariani J, Leet A, Kaye DM. Clinical utility of invasive exercise hemodynamic evaluation in LVAD patients. J Heart Lung Transplant 2015;34:1635-7.

28. Burrell AJ, Hare JL, Francis PJ, Fitzgerald M, Cooper DJ, Murphy D, Kaye DM, Taylor AJ. Impact of cardiac magnetic resonance imaging - cardiac contusion with intramural hemorrhage. Circ J 2015;79:216-7.

29. Burrell AJ, Pellegrino VA, Wolfe R, Wong WK, Cooper DJ, Kaye DM, Pilcher DV. Long-term survival of adults with cardiogenic shock after venoarterial extracorporeal membrane oxygenation. J Crit Care 2015;epub.

30. Cabrini L, Landoni G, Antonelli M, Bellomo R, Colombo S, Negro A, Pelosi P, Zangrillo A. Critical care in the near future: patient-centered, beyond space and time boundaries. Minerva Anestesiol 2015;epub.

31. Calzavacca P, Evans RG, Bailey M, Bellomo R, May CN. Variable responses of regional renal oxygenation and perfusion to vasoactive agents in awake sheep. Am J Physiol Regul Integr Comp Physiol 2015;309:R1226-33.

32. Calzavacca P, Evans RG, Bailey M, Bellomo R, May CN. Cortical and Medullary Tissue Perfusion and Oxygenation in Experimental Septic Acute Kidney Injury. Crit Care Med 2015;43:e431-9.

33. Calzavacca P, Evans RG, Bailey M, Lankadeva YR, Bellomo R, May CN. Long-term measurement of renal cortical and medullary tissue oxygenation and perfusion in unanesthetized sheep. Am J Physiol Regul Integr Comp Physiol 2015;308:R832-9.

34. Chapman M, Peake S, Jones D. Gluttony in the ICU: is it really a deadly sin? Crit Care Resusc 2015;17:63-4.

35. Chen J, Bellomo R, Flabouris A, Hillman K, Assareh H, Ou L. Delayed Emergency Team Calls and Associated Hospital Mortality: A Multicenter Study. Crit Care Med 2015;43:2059-65.

Publications Publications (continued)

Journal Publications (continued)36. Chesnut RM, Bleck TP, Citerio G, Classen J, Cooper DJ, Coplin

WM, Diringer MN, Grande PO, Hemphill JC, Hutchinson PJ, Le Roux P, Mayer SA, Menon DK, Myburgh JA, Okonkwo DO, Robertson CS, Sahuquillo J, Stocchetti N, Sung G, Temkin N, Vespa PM, Videtta W, Yonas H. A Consensus-Based Interpretation of the Benchmark Evidence from South American Trials: Treatment of Intracranial Pressure Trial. J Neurotrauma 2015;32:1722-4.

37. Chiam E, Weinberg L, Bailey M, McNicol L, Bellomo R. The haemodynamic effects of intravenous paracetamol (acetaminophen) in healthy volunteers: a double-blinded, randomized, triple crossover trial. Br J Clin Pharmacol 2015;epub.

38. Cnossen MC, Scholten AC, Lingsma H, Synnot A, Tavender E, Gantner D, Lecky F, Steyerberg EW, Polinder S. Adherence to guidelines in adult patients with traumatic brain injury: A living systematic review. J Neurotrauma 2015;epub.

39. Cross G, Bilgrami I, Eastwood G, Johnson P, Howden BP, Bellomo R, Jones D. The epidemiology of sepsis during rapid response team reviews in a teaching hospital. Anaesth Intensive Care 2015;43:193-8.

40. Doig GS, Roberts I, Bellomo R. The tens of thousands of lives saved by randomized clinical trials in critical care. Intensive Care Med 2015;41:701-4.

41. Doig GS, Simpson F, Bellomo R, Heighes PT, Sweetman EA, Chesher D, Pollock C, Davies A, Botha J, Harrigan P, Reade MC. Intravenous amino acid therapy for kidney function in critically ill patients: a randomized controlled trial. Intensive Care Med 2015;41:1197-208.

42. Doig GS, Simpson F, Heighes PT, Bellomo R, Chesher D, Caterson ID, Reade MC, Harrigan PW. Restricted versus continued standard caloric intake during the management of refeeding syndrome in critically ill adults: a randomised, parallel-group, multicentre, single-blind controlled trial. Lancet Respir Med 2015;3:943-52.

43. Dooley N, Hew S, Nichol A. Acute pancreatitis: an intensive care perspective. Anaesth Intensive Care Med 2015;16:191-6.

44. Dulhunty JM, Roberts JA, Davis JS, Webb SA, Bellomo R, Gomersall C, Shirwadkar C, Eastwood GM, Myburgh J, Paterson DL, Starr T, Paul SK, Lipman J. A Multicenter Randomized Trial of Continuous versus Intermittent beta-Lactam Infusion in Severe Sepsis. Am J Respir Crit Care Med 2015;192:1298-305.

45. Eastwood GM, Schneider AG, Suzuki S, Bailey M, Bellomo R. A pilot feasibility, safety and biological efficacy multicentre trial of therapeutic hypercapnia after cardiac arrest: study protocol for a randomized controlled trial. Trials 2015;16:135.

46. Eastwood GM, Suzuki S, Lluch C, Schneider AG, Bellomo R. A pilot assessment of alpha-stat vs pH-stat arterial blood gas analysis after cardiac arrest. J Crit Care 2015;30:138-44.

47. Eastwood GM, Tanaka A, Espinoza ED, Peck L, Young H, Martensson J, Zhang L, Glassford NJ, Hsiao YF, Suzuki S, Bellomo R. Conservative oxygen therapy in mechanically ventilated patients following cardiac arrest: A retrospective nested cohort study. Resuscitation 2015;epub.

48. Entesari-Tatafi D, Orford N, Bailey MJ, Chonghaile MN, Lamb-Jenkins J, Athan E. Effectiveness of a care bundle to reduce central line-associated bloodstream infections. Med J Aust 2015;202:247-9.

49. Fairley J, Glassford NJ, Zhang L, Bellomo R. Magnesium status and magnesium therapy in critically ill patients: A systematic review. J Crit Care 2015;30:1349-58.

50. Farley KJ, Mitchell I, Jones D. A practical approach to end-of-life care rapid response team calls. Crit Care Resusc 2015;17:208-10.

51. Fealy N, Osborne C, Eastwood GM, Glassford N, Hart G, Bellomo R. Nasal high-flow oxygen therapy in ICU: A before-and-after study. Aust Crit Care 2015;epub.

52. Finfer S, Chittock D, Li Y, Foster D, Dhingra V, Bellomo R, Cook D, Dodek P, Hebert P, Henderson W, Heyland D, Higgins A, McArthur C, Mitchell I, Myburgh J, Robinson B, Ronco J. Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study. Intensive Care Med 2015;41:1037-47.

53. Fisher C, Karalapillai DK, Bailey M, Glassford N, Bellomo R, Jones D. Predicting intensive care and hospital outcome with the Dalhousie Clinical Frailty Scale: a pilot assessment. Anaesth Intensive Care 2015;43:361-8.

54. Forbes AB, Akram M, Pilcher D, Cooper J, Bellomo R. Cluster randomised crossover trials with binary data and unbalanced cluster sizes: application to studies of near-universal interventions in intensive care. Clin Trials 2015;12:34-44.

55. Gantner D, Mason C. Management of severe sepsis. Anaesth Intensive Care Med 2015;16:593-7.

56. Garcia-Alvarez M, Glassford NJ, Betbese AJ, Ordonez J, Banos V, Argilaga M, Martinez A, Suzuki S, Schneider AG, Eastwood GM, Victoria Moral M, Bellomo R. Urinary Neutrophil Gelatinase-Associated Lipocalin as Predictor of Short- or Long-Term Outcomes in Cardiac Surgery Patients. J Cardiothorac Vasc Anesth 2015;29:1480-8.

57. Garnero A, Hodgson C, Arnal JM. Transpulmonary pressure cannot be determined without esophageal pressure in ARDS patients. Minerva Anestesiol 2015;epub.

58. Garnero A, Tuxen D, Corno G, Durand-Gasselin J, Hodgson C, Arnal JM. Dynamics of end expiratory lung volume after changing positive end-expiratory pressure in acute respiratory distress syndrome patients. Crit Care 2015;19:340.

59. Garnero A, Tuxen D, Ducros L, Demory D, Donati SY, Durand-Gasselin J, Cooper J, Hodgson C, Arnal JM. Non-invasive assessment of lung elastance in patients with acute respiratory distress syndrome. Minerva Anestesiol 2015;81:1096-104.

60. Gattas DJ, Rajbhandari D, Bradford C, Buhr H, Lo S, Bellomo R. A Randomized Controlled Trial of Regional Citrate Versus Regional Heparin Anticoagulation for Continuous Renal Replacement Therapy in Critically Ill Adults. Crit Care Med 2015;43:1622-9.

61. Gelbart B, Glassford NJ, Bellomo R. Fluid Bolus Therapy-Based Resuscitation for Severe Sepsis in Hospitalized Children: A Systematic Review. Pediatr Crit Care Med 2015;16:e297-307.

62. Glassford NJ, Jones SL, Martensson J, Eastwood GM, Bailey M, Cross AM, Taylor DM, Bellomo R. Characteristics and expectations of fluid bolus therapy: a bi-national survey of acute care physicians. Anaesth Intensive Care 2015;43:750-6.

63. Greco M, Zangrillo A, Mucchetti M, Nobile L, Landoni P, Bellomo R, Landoni G. Democracy-based consensus in medicine. J Cardiothorac Vasc Anesth 2015;29:506-9.

64. Green A, Jones D, McIntyre T, Taylor C, Chaboyer W, Bailey M. Characteristics and outcomes of patients reviewed by intensive care unit liaison nurses in Australia: a prospective multicentre study. Crit Care Resusc 2015;17:244-52.

65. Green CR, Botha JA, Tiruvoipati R. Cognitive function, quality of life and mental health in survivors of our-of-hospital cardiac arrest: a review. Anaesth Intensive Care 2015;43:568-76.

66. Gujadhur A, Tiruvoipati R, Cole E, Malouf S, Ansari ES, Wong K. Serum bicarbonate may independently predict acute kidney injury in critically ill patients: An observational study. World J Crit Care Med 2015;4:71-6.

67. Gupta S, Tiruvoipati R, Green C. Atrial Fibrillation and Mortality in Critically Ill Patients: A Retrospective Study. Am J Crit Care 2015;24:336-41.

2322

Publications (continued)

Journal Publications (continued)68. Gupta S, Tiruvoipati R, Green C, Botha J, Tran H. Heparin

induced thrombocytopenia in critically ill: Diagnostic dilemmas and management conundrums. World J Crit Care Med 2015;4:202-12.

69. Harrois A, Baudry N, Huet O, Kato H, Dupic L, Lohez M, Ziol M, Vicaut E, Duranteau J. Norepinephrine Decreases Fluid Requirements and Blood Loss While Preserving Intestinal Villi Microcirculation during Fluid Resuscitation of Uncontrolled Hemorrhagic Shock in Mice. Anesthesiology 2015;122:1093-102.

70. Hellewell S, Semple BD, Morganti-Kossmann MC. Therapies negating neuroinflammation after brain trauma. Brain Res 2015;epub.

71. Hodgson C, Bellomo R, Berney S, Bailey M, Buhr H, Denehy L, Harrold M, Higgins A, Presneill J, Saxena M, Skinner E, Young P, Webb S. Early mobilization and recovery in mechanically ventilated patients in the ICU: a bi-national, multi-centre, prospective cohort study. Crit Care 2015;19:81.

72. Hodgson CL, Fan E. Intensive care unit acquired weakness. Anaesth Intensive Care Med 2015;17:24-6.

73. Iwashyna TJ, Burke JF, Sussman JB, Prescott HC, Hayward RA, Angus DC. Reply: Risk-based Heterogeneity of Treatment Effect in Trials and Implications for Surveillance of Clinical Effectiveness Using Regression Discontinuity Designs. Am J Respir Crit Care Med 2015;192:1399-400.

74. Iwashyna TJ, Burke JF, Sussman JB, Prescott HC, Hayward RA, Angus DC. Implications of Heterogeneity of Treatment Effect for Reporting and Analysis of Randomized Trials in Critical Care. Am J Respir Crit Care Med 2015;192:1045-51.

75. Iwashyna TJ, Hodgson CL, Pilcher D, Bailey M, Bellomo R. Persistent critical illness characterised by Australian and New Zealand ICU clinicians. Crit Care Resusc 2015;17:153-8.

76. Iwashyna TJ, Hodgson CL, Pilcher D, Orford N, Santamaria JD, Bailey M, Bellomo R. Towards defining persistent critical illness and other varieties of chronic critical illness. Crit Care Resusc 2015;17:215-8.

77. Jones D, DeVita M, Warrillow S. Ten clinical indicators suggesting the need for ICU admission after Rapid Response Team review. Intensive Care Med 2015;epub.

78. Jones D, Hicks P, Currey J, Holmes J, Fennessy GJ, Hillman K, Psirides A, Rai S, Singh MY, Pilcher DV, Bhonagiri D, Hart GK, Fugaccia E. Findings of the first ANZICS conference on the role of intensive care in Rapid Response Teams. Anaesth Intensive Care 2015;43:369-79.

79. Jones D, Hilton A, Bellomo R. Extracorporeal membrane oxygenation for inhospital cardiac arrests: the rise of the machines. Crit Care Resusc 2015;17:3-5.

80. Jones D, Lippert A, DeVita M, Hillman K. What’s new with rapid response systems? Intensive Care Med 2015;41:315-7.

81. Jones SL, Martensson J, Glassford NJ, Eastwood GM, Bellomo R. Loop diuretic therapy in the critically ill: a survey. Crit Care Resusc 2015;17:223-6.

82. Jones SL, Tanaka A, Eastwood GM, Young H, Peck L, Bellomo R, Martensson J. Bioelectrical impedance vector analysis in critically ill patients: a prospective, clinician-blinded investigation. Crit Care 2015;19:290.

83. Kaukonen KM, Bailey M, Pilcher D, Cooper DJ, Bellomo R. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med 2015;372:1629-38.

84. Kaukonen KM, Bailey M, Bellomo R. Systemic Inflammatory Response Syndrome Criteria for Severe Sepsis. N Engl J Med 2015;373:881.

85. Kellum JA, Bellomo R, Ronco C. Does this patient have acute kidney injury? An AKI checklist. Intensive Care Med 2015;epub.

86. Kennedy MP, Wilson K, Gabbe BJ, Straney L, Bailey M. Retrieval Rapid Emergency Medical Score in retrieval medicine. Emerg Med Australas 2015;epub.

87. Kramer RD, Cooke CR, Liu V, Miller RR, Iwashyna TJ. Variation in the Contents of Sepsis Bundles and Quality Measures. A Systematic Review. Ann Am Thorac Soc 2015;12:1676-84.

88. Lankadeva YR, Booth LC, Kosaka J, Evans RG, Quintin L, Bellomo R, May CN. Clonidine Restores Pressor Responsiveness to Phenylephrine and Angiotensin II in Ovine Sepsis. Crit Care Med 2015;43:e221-9.

89. Li G, Cook DJ, Levine MA, Guyatt G, Crowther M, Heels-Ansdell D, Holbrook A, Lamontagne F, Walter SD, Ferguson ND, Finfer S, Arabi YM, Bellomo R, Cooper DJ, Thabane L. Competing Risk Analysis for Evaluation of Dalteparin Versus Unfractionated Heparin for Venous Thromboembolism in Medical-Surgical Critically Ill Patients. Medicine (Baltimore) 2015;94:e1479.

90. Ling VY, Lee D, McQuilten Z, Avery S, Low M, Cody SH, Nguyen T, McLean C, Gorniak M, Wei A, Ting SB. Immunological markers for prognostication in cytogenetically normal acute myeloid leukemia. Am J Hematol 2015;90:E219-20.

91. Lipcsey M, Castegren M, Bellomo R. Hemodynamic management of septic shock. Minerva Anestesiol 2015;81:1262-72.

92. Lipcsey M, Chiong J, Subiakto I, Kaufman MA, Schneider AG, Bellomo R. Primary fluid bolus therapy for infection-associated hypotension in the emergency department. Crit Care Resusc 2015;17:6-11.

93. Martensson J, Bellomo R. Perioperative renal failure in elderly patients. Curr Opin Anaesthesiol 2015;28:123-30.

94. Martensson J, Bellomo R. Are all fluids bad for the kidney? Curr Opin Crit Care 2015;21:292-301.

95. Martensson J, Bellomo R. Sepsis-Induced Acute Kidney Injury. Crit Care Clin 2015;31:649-60.

96. Martensson J, Bellomo R. Attenuating Acute Kidney Injury: Does It Pay to Be “Noble”? Crit Care Med 2015;43:1554-5.

97. Martensson J, Glassford NJ, Jones S, Eastwood GM, Young H, Peck L, Ostland V, Westerman M, Venge P, Bellomo R. Urinary neutrophil gelatinase-associated lipocalin to hepcidin ratio as a biomarker of acute kidney injury in intensive care unit patients. Minerva Anestesiol 2015;81:1192-200.

98. McQuilten ZK, Andrianopoulos N, van de Watering L, Aubron C, Phillips L, Bellomo R, Pilcher D, Cameron P, Reid CM, Cole-Sinclair MF, Newcomb A, Smith J, McNeil JJ, Wood EM. Introduction of universal prestorage leukodepletion of blood components, and outcomes in transfused cardiac surgery patients. J Thorac Cardiovasc Surg 2015;150:216-22.

99. McQuilten ZK, Crighton G, Engelbrecht S, Gotmaker R, Brunskill SJ, Murphy MF, Wood EM. Transfusion interventions in critical bleeding requiring massive transfusion: a systematic review. Transfus Med Rev 2015;29:127-37.

100. McQuilten ZK, Sundararajan V, Andrianopoulos N, Curtis DJ, Wood EM, Campbell LJ, Wall M. Monosomal karyotype predicts inferior survival independently of a complex karyotype in patients with myelodysplastic syndromes. Cancer 2015;121:2892-9.

101. Milnes S, Orford NR, Berkeley L, Lambert N, Simpson N, Elderkin T, Corke C, Bailey M. A prospective observational study of prevalence and outcomes of patients with Gold Standard Framework criteria in a tertiary regional Australian Hospital. BMJ Support Palliat Care 2015;epub.

102. Moore E, Tobin A, Reid D, Santamaria J, Paul E, Bellomo R. The Impact of Fluid Balance on the Detection, Classification and Outcome of Acute Kidney Injury After Cardiac Surgery. J Cardiothorac Vasc Anesth 2015;29:1229-35.


103. Mora JC, Schneider A, Robbins R, Bailey M, Bebee B, Hsiao YF, Considine J, Jones D, Bellomo R. Epidemiology of early Rapid Response Team activation after Emergency Department admission. Australas Emerg Nurs J 2015;epub.

104. Morgan TJ, Venkatesh B, Bellomo R. Acid-base physiology: comments on 10 contentious assertions. Crit Care Resusc 2015;17:211-3.

105. Muriel A, Penuelas O, Frutos-Vivar F, Arroliga AC, Abraira V, Thille AW, Brochard L, Nin N, Davies AR, Amin P, Du B, Raymondos K, Rios F, Violi DA, Maggiore SM, Soares MA, Gonzalez M, Abroug F, Bulow HH, Hurtado J, Kuiper MA, Moreno RP, Zeggwagh AA, Villagomez AJ, Jibaja M, Soto L, D’Empaire G, Matamis D, Koh Y, Anzueto A, Ferguson ND, Esteban A. Impact of sedation and analgesia during noninvasive positive pressure ventilation on outcome: a marginal structural model causal analysis. Intensive Care Med 2015;41:1586-600.

106. Murphy DA, Hockings LE, Andrews RK, Aubron C, Gardiner EE, Pellegrino VA, Davis AK. Extracorporeal membrane oxygenation-hemostatic complications. Transfus Med Rev 2015;29:90-101.

107. Nichol A, French C, Little L, Haddad S, Presneill J, Arabi Y, Bailey M, Cooper DJ, Duranteau J, Huet O, Mak A, McArthur C, Pettila V, Skrifvars M, Vallance S, Varma D, Wills J, Bellomo R. Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial. Lancet 2015;386:2499-506.

108. Nichol A, French C, Little L, Presneill J, Cooper DJ, Haddad S, Duranteau J, Huet O, Skrifvars M, Arabi Y, Bellomo R. Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial. Trials 2015;16:528.

109. Nichol A, Gantner D, Presneill J, Murray L, Trapani T, Bernard S, Cameron P, Capellier G, Forbes A, McArthur C, Newby L, Rashford S, Rosenfeld JV, Smith T, Stephenson M, Varma D, Walker T, Webb S, Cooper DJ. Protocol for a multicentre randomised controlled trial of early and sustained prophylactic hypothermia in the management of traumatic brain injury. Crit Care Resusc 2015;17:92-100.

110. O’Connor C, Nichol A. Inflammation, immunity and allergy. Anaesth Intensive Care Med 2015;16:328-33.

111. Orford NR, Lane SE, Bailey M, Pasco JA, Cattigan C, Elderkin T, Brennan-Olsen SL, Bellomo R, Cooper DJ, Kotowicz MA. Changes in Bone Mineral Density in the Year After Critical Illness. Am J Respir Crit Care Med 2015;epub.

112. Panwar R, Hardie M, Bellomo R, Barrot L, Eastwood GM, Young PJ, Capellier G, Harrigan PW, Bailey M. Conservative Versus Liberal Oxygenation Targets for Mechanically Ventilated Patients - a Pilot Multicenter Randomized Controlled Trial. Am J Respir Crit Care Med 2015;epub.

113. Parke RL, Bloch A, McGuinness SP. Effect of Very-High-Flow Nasal Therapy on Airway Pressure and End-Expiratory Lung Impedance in Healthy Volunteers. Respir Care 2015;60:1397-403.

114. Parke RL, McGuinness SP, Gilder E, McCarthy LW, Cowdrey KA. A randomised feasibility study to assess a novel strategy to rationalise fluid in patients after cardiac surgery. Br J Anaesth 2015;115:45-52.

115. Peake S, Angus D, Rowan K. Early goal-directed therapy versus “early”, “goal-directed” therapy: response to comments by Saleh. Intensive Care Med 2015;41:1725-6.

116. Peake SL, Delaney A, Bellomo R. Goal-directed resuscitation in septic shock. N Engl J Med 2015;372:190-1.

117. Perner A, Fowler RA, Bellomo R, Roberts I. Ebola care and research protocols. Intensive Care Med 2015;41:111-4.

118. Pilcher D, Gladkis L, Arcia B, Bailey M, Cook D, Cass Y, Opdam H. Estimating the Number of Organ Donors in Australian Hospitals--Implications for Monitoring Organ Donation Practices. Transplantation 2015;99:2203-9.

119. Piton G, Capellier G. Plasma citrulline in the critically ill: intriguing biomarker, cautious interpretation. Crit Care 2015;19:204.

120. Piton G, Cypriani B, Regnard J, Patry C, Puyraveau M, Capellier G. Catecholamine Use is Associated With Enterocyte Damage in Critically Ill Patients. Shock 2015;43:437-42.

121. Price J, Hoy J, Ridley E, Nyulasi I, Paul E, Woolley I. Changes in the prevalence of lipodystrophy, metabolic syndrome and cardiovascular disease risk in HIV-infected men. Sexual Health 2015;12:240-8.

122. Prowle JR, Bellomo R. Sepsis-Associated Acute Kidney Injury: Macrohemodynamic and Microhemodynamic Alterations in the Renal Circulation. Semin Nephrol 2015;35:64-74.

123. Reddy SK, Young PJ, Beasley RW, Mackle DM, McGuinness SP, McArthur CJ, Henderson SJ, Weinberg L, French CJ, Orford NR, Bailey MJ, Bellomo R. Overview of the study protocols and statistical analysis plan for the Saline versus Plasma-Lyte 148 for Intravenous Fluid Therapy (SPLIT) research program. Crit Care Resusc 2015;17:29-36.

124. Reith FC, Van den Brande R, Synnot A, Gruen R, Maas AI. The reliability of the Glasgow Coma Scale: a systematic review. Intensive Care Med 2016;42:3-15.

125. Ridley E, Davies A, Cooper DJ. Full-feeding with enteral nutrition is not always “full-feeding” in research and clinical practice. J Parenter Enteral Nutr 2015;39:383.

126. Ridley E, Gantner D, Pellegrino V. Nutrition therapy in critically ill patients- a review of current evidence for clinicians. Clin Nutr 2015;34:565-71.

127. Ridley E, Gantner D, Pellegrino V. Reply Letter to the Editor - Nutrition therapy in critically ill patients - A review of current evidence for clinicians. Clin Nutr 2015;epub.

128. Ridley EJ, Davies AR, Hodgson C, Deane A, Bailey M, Cooper DJ. Full predicted energy from nutrition and the effect on mortality and infectious complications in critically ill adults: a protocol for a systematic review and meta-analysis of parallel randomised controlled trials. Syst Rev 2015;4:179.

129. Ridley EJ, Davies AR, Parke R, Bailey M, McArthur C, Gillanders L, Cooper DJ, McGuinness S. Supplemental parenteral nutrition in critically ill patients: a study protocol for a phase II randomised controlled trial. Trials 2015;16:587.

130. Ridley EJ, Davies AR, Robins EJ, Lukas G, Bailey MJ, Fraser JF. Nutrition therapy in adult patients receiving extracorporeal membrane oxygenation: a prospective, multicentre, observational study. Crit Care Resusc 2015;17:183-9.

131. Rosenfeld JV, Cooper DJ. Commentary on “the role of evidence based medicine in neurotrauma”. J Clin Neurosci 2015;22:617-8.

132. Santamaria JD, Duke GJ, Pilcher DV, Cooper DJ, Moran J, Bellomo R. The timing of discharge from the intensive care unit and subsequent mortality. A prospective, multicenter study. Am J Respir Crit Care Med 2015;191:1033-9.

Journal Publications (continued)

2524

163. Weber U, Glassford NJ, Eastwood GM, Bellomo R, Hilton AK. A Pilot Assessment of Carotid and Brachial Artery Blood Flow Estimation Using Ultrasound Doppler in Cardiac Surgery Patients. J Cardiothorac Vasc Anesth 2015;epub.

164. Weber U, Glassford NJ, Eastwood GM, Bellomo R, Hilton AK. A pilot study of the relationship between Doppler-estimated carotid and brachial artery flow and cardiac index. Anaesthesia 2015;70:1140-7.

165. Weinkove R, Bailey M, Bellomo R, Saxena MK, Tam CS, Pilcher DV, Beasley R, Young PJ. Association between early peak temperature and mortality in neutropenic sepsis. Ann Hematol 2015;94:857-64.

166. Wong BT, Chan MJ, Glassford NJ, Martensson J, Bion V, Chai SY, Oughton C, Tsuji IY, Candal CL, Bellomo R. Mean arterial pressure and mean perfusion pressure deficit in septic acute kidney injury. J Crit Care 2015;epub.

167. Yan EB, Frugier T, Lim CK, Heng B, Sundaram G, Tan M, Rosenfeld JV, Walker DW, Guillemin GJ, Morganti-Kossmann MC. Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans. J Neuroinflammation 2015;12:110.

168. Young P, Bailey M, Beasley R, Henderson S, Mackle D, McArthur C, McGuinness S, Mehrtens J, Myburgh J, Psirides A, Reddy S, Bellomo R. Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial. JAMA 2015:1-10.

169. Young P, Saxena M, Bellomo R, Freebairn R, Hammond N, van Haren F, Holliday M, Henderson S, Mackle D, McArthur C, McGuinness S, Myburgh J, Weatherall M, Webb S, Beasley R. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. N Engl J Med 2015;373:2215-24.

170. Young PJ, Beasley RW, Capellier G, Eastwood GM, Webb SA. Oxygenation targets, monitoring in the critically ill: a point prevalence study of clinical practice in Australia and New Zealand. Crit Care Resusc 2015;17:202-7.

171. Yunos NM, Bellomo R, Glassford N, Sutcliffe H, Lam Q, Bailey M. Chloride-liberal vs. chloride-restrictive intravenous fluid administration and acute kidney injury: an extended analysis. Intensive Care Med 2015;41:257-64.

172. Zatta A, McQuilten Z, Kandane-Rathnayake R, Isbister J, Dunkley S, McNeil J, Cameron P, Phillips L. The Australian and New Zealand Haemostasis Registry: ten years of data on off-licence use of recombinant activated factor VII. Blood Transfus 2015;13:86-99.

173. Gantner D. Chapter 80: Postoperative Fluid Therapy. In: Symons J, Myles PS, Mehra R, Ball CM, eds. Perioperative Medicine for the Junior Clinician (ISBN: 9781118779163). Hoboken, USA: Wiley Blackwell; 2015.

174. Loughnan T, Gantner D, Kolawole H, Naughton M, Nixon P, Tuxen D. Chapter 105: Case Studies 10 - Miscellaneous. In: Symons J, Myles PS, Mehra R, Ball CM, eds. Perioperative Medicine for the Junior Clinician (ISBN: 9781118779163). Hoboken, USA: Wiley Blackwell; 2015.

175. Martensson J, Bellomo R. Sepsis-Induced Acute Kidney Injury. In: Kellum JA, Carlson RW, eds. Critical Care Clinics: Nephrology (ISBN: 978-0-323-40078-7). New York, NY, USA: Elsevier; 2015:649-60.

176. Schmidt M, Hodgson C, Combes A. Extracorporeal Gas Exchange for Acute Respiratory Failure in Adult Patients: A Systematic Review. In: Vincent JL, ed. Annual Update in Intensive Care and Emergency Medicine 2015 (ISBN: 978-3-319-13760-5). Switzerland: Springer International; 2015:179-206.


133. Saxena M, Young P, Pilcher D, Bailey M, Harrison D, Bellomo R, Finfer S, Beasley R, Hyam J, Menon D, Rowan K, Myburgh J. Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection. Intensive Care Med 2015;41:823-32.

134. Schmidt M, Burrell A, Roberts L, Bailey M, Sheldrake J, Rycus PT, Hodgson C, Scheinkestel C, Cooper DJ, Thiagarajan RR, Brodie D, Pellegrino V, Pilcher D. Predicting survival after ECMO for refractory cardiogenic shock: the survival after veno-arterial-ECMO (SAVE)-score. Eur Heart J 2015;36:2246-56.

135. Schmidt M, Hodgson C, Combes A. Extracorporeal gas exchange for acute respiratory failure in adult patients: a systematic review. Crit Care 2015;19:806.

136. Schmidt M, Stewart C, Bailey M, Nieszkowska A, Kelly J, Murphy L, Pilcher D, Cooper DJ, Scheinkestel C, Pellegrino V, Forrest P, Combes A, Hodgson C. Mechanical ventilation management during extracorporeal membrane oxygenation for acute respiratory distress syndrome: a retrospective international multicenter study. Crit Care Med 2015;43:654-64.

137. Schneider AG, Schelleman A, Goodwin MD, Bailey M, Eastwood GM, Bellomo R. Contrast-enhanced ultrasound evaluation of the renal microcirculation response to terlipressin in hepato-renal syndrome: a preliminary report. Ren Fail 2015;37:175-9.

138. Shehabi Y, Rachakonda KS, Bailey MJ, Peake S. Reply: no significant reduction in antibiotic treatment using a procalcitonin algorithm with low cutoff value in the intensive care unit? Am J Respir Crit Care Med 2015;191:859-60.

139. Sime FB, Udy AA, Roberts JA. Augmented renal clearance in critically ill patients: etiology, definition and implications for beta-lactam dose optimization. Curr Opin Pharmacol 2015;24:1-6.

140. Sjoding MW, Luo K, Miller MA, Iwashyna TJ. When do confounding by indication and inadequate risk adjustment bias critical care studies? A simulation study. Crit Care 2015;19:195.

141. Skinner EH, Haines KJ, Howe B, Hodgson CL, Denehy L, McArthur CJ, Seller D, Di Marco E, Mulvany K, Ryan DT, Berney S. Health-Related Quality of Life in Australasian Survivors of H1N1 Influenza Undergoing Mechanical Ventilation. A Multicenter Cohort Study. Ann Am Thorac Soc 2015;12:895-903.

142. Smith GB, Welch J, DeVita MA, Hillman KM, Jones D. Education for cardiac arrest - Treatment or prevention? Resuscitation 2015;92:59-62.

143. Smith GB, Welch J, DeVita MA, Hillman KM, Jones D. Reply to Letter: ‘Re: Education for cardiac arrest - Prevention and treatment’. Resuscitation 2015;96:e9-e10.

144. Smith GB, Welch J, DeVita MA, Hillman KM, Jones D. Reply to Letter: ‘Re: Education for cardiac arrest - Treatment or prevention?’. Resuscitation 2015;96:e13-4.

145. Stub D, Bernard S, Pellegrino V, Smith K, Walker T, Sheldrake J, Hockings L, Shaw J, Duffy SJ, Burrell A, Cameron P, Smit de V, Kaye DM. Refractory cardiac arrest treated with mechanical CPR, hypothermia, ECMO and early reperfusion (the CHEER trial). Resuscitation 2015;86:88-94.

146. Stub D, Smith K, Bernard S, Nehme Z, Stephenson M, Bray JE, Cameron P, Barger B, Ellims AH, Taylor AJ, Meredith IT, Kaye DM. Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction. Circulation 2015;131:2143-50.

147. Sutherasan Y, Penuelas O, Muriel A, Vargas M, Frutos-Vivar F, Brunetti I, Raymondos K, D’Antini D, Nielsen N, Ferguson ND, Bottiger BW, Thille AW, Davies AR, Hurtado J, Rios F, Apezteguia C, Violi DA, Cakar N, Gonzalez M, Du B, Kuiper MA, Soares MA, Koh Y, Moreno RP, Amin P, Tomicic V, Soto L, Bulow HH, Anzueto A, Esteban A, Pelosi P, Ventila G. Management and outcome of mechanically ventilated patients after cardiac arrest. Crit Care 2015;19:215.

148. Suzuki S, Eastwood GM, Bailey M, Gattas D, Kruger P, Saxena M, Santamaria JD, Bellomo R. Paracetamol therapy and outcome of critically ill patients: a multicenter retrospective observational study. Crit Care 2015;19:162.

149. Suzuki S, Eastwood GM, Goodwin MD, Noe GD, Smith PE, Glassford N, Schneider AG, Bellomo R. Atelectasis and mechanical ventilation mode during conservative oxygen therapy: A before-and-after study. J Crit Care 2015;30:1232-7.

150. Synnot A, Gruen RL, Menon D, Steyerberg EW, Buki A, Peul W, Elliott JH, Maas A. A new approach to evidence synthesis in traumatic brain injury: Living systematic reviews. J Neurotrauma 2015;epub.

151. Tatucu-Babet OA, Ridley EJ, Tierney AC. The Prevalence of Underprescription or Overprescription of Energy Needs in Critically Ill Mechanically Ventilated Adults as Determined by Indirect Calorimetry: A Systematic Literature Review. J Parenter Enteral Nutr 2015;epub.

152. Topple M, Ryan B, McKay R, Blythe D, Rogan J, Baldwin I, Jones D. Features of an Intensive Care based Medical Emergency Team nurse training program in a University Teaching Hospital. Aust Crit Care 2015;epub.

153. Tramm R, Hodgson C, Ilic D, Sheldrake J, Pellegrino V. Identification and prevalence of PTSD risk factors in ECMO patients: A single centre study. Aust Crit Care 2015;28:31-6.

154. Tramm R, Ilic D, Davies AR, Pellegrino VA, Romero L, Hodgson C. Extracorporeal membrane oxygenation for critically ill adults. Cochrane Database Syst Rev 2015;1:CD010381.

155. Trentino KM, Farmer SL, Swain SG, Burrows SA, Hofmann A, Ienco R, Pavey W, Daly FF, Van Niekerk A, Webb SA, Towler S, Leahy MF. Increased hospital costs associated with red blood cell transfusion. Transfusion 2015;55:1082-9.

156. Turunen H, Jakob SM, Ruokonen E, Kaukonen KM, Sarapohja T, Apajasalo M, Takala J. Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation. Crit Care 2015;19:67.

157. Udy AA, Scheinkestel C, Pilcher D, Bailey M. The Association Between Low Admission Peak Plasma Creatinine Concentration and In-Hospital Mortality in Patients Admitted to Intensive Care in Australia and New Zealand. Crit Care Med 2015;epub.

158. Valley TS, Sjoding MW, Ryan AM, Iwashyna TJ, Cooke CR. Association of Intensive Care Unit Admission With Mortality Among Older Patients With Pneumonia. JAMA 2015;314:1272-9.

159. Venkatesh B, Imeson L, Kruger P, Cohen J, Jones M, Bellomo R. Elevated plasma-free cortisol concentrations and ratios are associated with increased mortality even in the presence of statin therapy in patients with severe sepsis. Crit Care Med 2015;43:630-5.

160. Venkatesh B, Pilcher D, Prins J, Bellomo R, Morgan TJ, Bailey M. Incidence and outcome of adults with diabetic ketoacidosis admitted to ICUs in Australia and New Zealand. Crit Care 2015;19:451.

161. Wang J, McQuilten ZK, Wood EM, Aubron C. Intravenous immunoglobulin in critically ill adults: When and what is the evidence? J Crit Care 2015;30:652 e9-16.

162. Warrillow S, Farley KJ, Jones D. Ten practical strategies for effective communication with relatives of ICU patients. Intensive Care Med 2015;41:2173-6.

Book Chapters




2726

Presentations - National / International Month Conference Location Name Title Role/s

Jan International Forum of Acute Care Trialists Meeting

Canada Webb S 1. A pandemic research preparedness consortium for Australia

2. A Short Period Incidence Study of Severe Acute Respiratory Illness

Invited Presenter

Jan Research Meeting ICU King Fahad National Guard Hospital

Riyadh, Saudi Arabia

Little L EPO-TBI Update Invited Presenter

Jan Research Meeting ICU King Fahad National Guard Hospital

Riyadh, Saudi Arabia

Little L Monitoring a clinical trial Invited Presenter

Feb Australian Resuscitation Council Spark of Life Conference

Melbourne, Australia

Reade M Massive bleeding - the military experience Invited Presenter

Feb Clinical Nutrition Week Los Angeles, USA

Chapman M TARGET Nutrition Study Phase III Invited Presenter

Feb International ECMO Network Milan, Italy

Hodgson C ECMO-PT - a multicentre RCT Invited Presenter

Mar 17th ANZICS-CTG Annual Meeting on Clinical Trials in Intensive Care (CT in IC)

Noosa, Australia

Ady B TRANSFUSE Study Update Invited Presenter

Mar 17th ANZICS-CTG Annual Meeting on CT in IC

Noosa, Australia

Arabi Y 1. Update on the Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

2. PREVENT

Invited Presenter


Noosa, Australia

Bellomo R 1. STARRT Update2. PLUS

Invited Presenter


Noosa, Australia

Cooper DJ 1. PHARLAP Update2. POLAR Update

Invited Presenter


Noosa, Australia

Eastwood G CCC Trial - Preliminary Results Invited Presenter


Noosa, Australia

Gantner D (with Gruen R)

PATCH Study Update Invited Presenter


Noosa, Australia

Huckson S, Pilcher D

CORE / CTG Workshop Update Invited Presenters


Noosa, Australia

Little L, Bellomo R

EPO-TBI Update Invited Presenters


Noosa, Australia

McArthur C 1. Chair: Session 12. CTG Update

Chair and Invited Presenter


Noosa, Australia

McGuinness S Chair: Session 6 Chair


Noosa, Australia

Myburgh JA 1. Results of the CHEST/6S individual patient-data meta-analysis

2. Update of CHEST and Medical Regulatory Authorities

Invited Presenter


Noosa, Australia

Orford N Bone turnover following critical illness Invited Presenter


Noosa, Australia

Parke R 1. Chair: Session 22. IRCIG Update

Chair


Noosa, Australia

Peake S 1. SMARRT Update2. TARGET Update3. Chair: Session 44. ARISE Has Risen5. IPDMA Update

Invited Presenter


Noosa, Australia

Reade M DahLIA Results Invited Presenter


Noosa, Australia

Rowan K “Room for improvement …?” Invited Presenter


Noosa, Australia

Shehabi Y SPICE Update Invited Presenter

Presentations - National / International (continued)

Month Conference Location Name Title Role/s


Noosa, Australia

Webb S The Australian Clinical Trials Alliance Invited Presenter

Mar 17th ANZICS-CTG Annual Meeting on CT in IC: Intensive Care Research Coordinator Interest Group (IRCIG) Workshop Program

Noosa, Australia

Eastwood G 1. Seeing the forest from the plot: explaining those statistical procedures and graphs

2. Chair, Session 3

Invited Presenter

Mar 17th ANZICS-CTG Annual Meeting on CT in IC: IRCIG Workshop Program

Noosa, Australia

Howe B Curricula Vitae - styles and tips Invited Presenter


Noosa, Australia

Little L Budgeting - the cold hard facts of research Invited Presenter


Noosa, Australia

Murray L Risk management Invited Presenter


Noosa, Australia

Orford N Tweet me!! Social media’s role in critical care trials Invited Presenter


Noosa, Australia

Parke R 1. Chair: Session 12. IRCIG



Noosa, Australia

Rowan K 1. Facing the challenges of emergency and critical care research together

2. The trials and tribulations of sepsis

Invited Presenter

Mar 17th ANZICS-CTG Annual Meeting on CT in IC: Pre-clinical Research Meeting

Noosa, Australia

Bellomo R 1. Chair (with Bersten A)2. Understanding renal physiology: sepsis,

radiocontrast and sympathetic system manipulation


Mar 32nd English Society for Cardiothoracic Surgery and Association of Cardiothoracic Anaesthetists Spring Meeting

Manchester, England

Schmidt M Extra-corporeal support for respiratory failure Invited Presenter

Mar 35th ESICEM ASM Brussels, Belgium

Bellomo R 1. Impact of SIRS criteria in defining sepsis2. How do set up a rapid response team3. Hemodynamic alterations in AKI4. How to prevent AKI5. Transfusion in AKI6. Bicarbonate to prevent renal damage7. Understanding NGAL8. Bolus fluid resuscitation in severe sepsis9. Albumin – which concentration?10. Effects of oxygen on mechanical ventilation11. The intensity of renal support delays recovery12. Lactate as a biomarker of hypoperfusion in sepsis

Invited Presenter

Mar Annual Scientific Meeting of Royal College of Pathologists of Australasia: Pathology Update


Cooper DJ Clinical impact of fresher transfused blood Chair

Mar International Symposium on Intensive Care and Emergency Medicine

Brussels, Belgium

Reade M 1. Why so many negative trials in trauma? Hypertonic solutions in trauma Military vs civilian trauma guidelines: How they differ What have we learned from military practice? What have we learned from military practice?

Invited Presenter

Mar National DonateLife Forum Melbourne, Australia

Pilcher DV Estimating Australian Donor Numbers Invited Presenter

Mar Platform foR European Preparedness Against (Re-)emerging Epidemics Annual meeting

Italy Webb S Preparing beyond Europe Invited Presenter

2928

Presentations - National / International (continued) Month Conference Location Name Title Role/s

Apr 3rd Singapore-ANZICS Intensive Care Forum

Singapore Bellomo R 1. Septic kidney injury2. Renal recovery and dialytic modality in the ICU3. Diuretic Therapy in the ICU

Invited Presenter

Apr 3rd Singapore-ANZICS Intensive Care Forum

Singapore Peake S 1. Optimisation of antimicrobial dosing in the ICU2. Caloric supplementation in the ICU3. Early goal-directed therapy: what now

Invited Presenter

May 32nd Dietitians Association of Australia Conference

Perth, Australia

Ridley E Using technology to enhance practice in clinical dietetics Invited Presenter

May ANZCA ASM Adelaide, Australia

Peake S The ARISE study and EGDT in sepsis Invited Presenter

May College of Intensive Care Medicine of ANZ Annual Scientific Meeting

Darwin, Australia

Webb S 1. Australasian Resuscitation In Sepsis Evaluation: ARISE to the Challenge

2. Interpandemic Planning – What’s Going on Right Now

Invited Presenter

May EuroELSO 2015- 4th International Congress

Regensburg, Germany

Schmidt M The urgent need for real studies in ECLS: what can be done?

Invited Presenter

May EuroELSO 2015- 4th International Congress

Regensburg, Germany

Tramm R Best abstract section, title: Back to the future? Health trajectory in ECMO survivors over time.

Invited Presenter

May Okayama Medical School 50th Anniversary Meeting

Okayama, Japan

Bellomo R 1. Septic AKI2. Oxygen therapy in ICU

Invited Presenter

May Royal Australasian College of Physicians ASM

Cairns, Australia

Bellomo R Septic Acute Kidney Injury Invited Presenter

May Symposium on traumatic brain Injury, Karolinska University Hospital, Stockholm, Sweden

Stockholm, Sweden

Morganti-Kossmann, C

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid in patients with traumatic brain injury

Invited Presenter

Jun 2nd Collaborative Clinical Trials in Intensive Care Medicine (ICM) Conference

Prato, Italy

Bellomo R 1. SPLIT Study2. EPO-TBI Patient Characteristics

Invited Presenter

Jun 2nd Collaborative Clinical Trials in ICM Conference

Prato, Italy

Capellier G POLAR RCT Europe: Eastern France Invited Presenter



Prato, Italy

Cooper DJ 1. ABLE Study results: Is fresh blood really better? (Chair)2. Transfusion and sepsis (Chair)3. SPLIT Study (Chair)4. TRANSFUSE RCT Europe (Chair)5. RESCUE-ICP and RESCUE-ASDH RCTs (Chair)6. ATACAS Aspirin results (Chair)

Conference Convenor and Chair


Prato, Italy

Hodgson C 1. Emerging trends in ICU Recovery2. Early interventions to maximise ICU Recovery (Panel

Member)

Invited Presenter


Prato, Italy

Huet O POLAR RCT Europe: Western France Invited Presenter


Prato, Italy

Kaukonen M 1. TRANSFUSE RCT Europe (Panel with Nichol A, Walsh T, Pettila V)

2. Sepsis Epidemiology

Invited Presenter


Prato, Italy

Nichol A 1. PHARLAP RCT: Where are we at?2. TRANSFUSE RCT Europe (Panel with Kaukonen M,

Walsh T, Pettila V)

Invited Presenter


Prato, Italy

Pettila V TRANSFUSE RCT Europe (Panel with Nichol A, Kaukonen M, Walsh T)

Invited Presenter


Prato, Italy

Rowan K ProMISe RCT Results Invited Presenter


Prato, Italy

Schmidt M 1. Interaction of VV ECMO and Ventilation2. LIFEGARDS Update3. EOLIA Study Update4. New ECMO studies (Panel with Brodie D, Fan E,

Pellegrino V)

Invited Presenter


Prato, Italy

Webb S ARISE RCT Results Invited Presenter

Jun The Fine Art of Clinical Trials Prato, Italy

Higgins L Health economics and knowledge translation Invited Presenter

3130

Presentations - National / International (continued) Presentations - National / International (continued) Month Conference Location Name Title Role/s


McArthur C 1. Presenting and publishing Workshop (with Chiche J-D)2. Participating in research networks (with Cuthbertson B)

Invited Presenter


McGuinness S

1. Critical care and general journals - what goes where2. Interacting with trial sites

Invited Presenter


Murray L 1. Budgeting for a project2. Managing risk

Invited Presenter


Nichol A 1. What should I research2. Choosing endpoints for trials3. Ethics across borders

Invited Presenter


Webb S 1. Seeking the truth in research2. Programs versus projects3. Making committees work4. Getting the money workshop (with Chiche J-D)

Invited Presenter

Jun 33rd Vicenza Course on Critical Care Nephrology

Vicenza, Italy

Bellomo R 1. Incidence and outcome of AKI in sepsis and MOF2. How do circuits fail?3. Does renal functional reserve exist in ICU patients?

Impact of treatment modality and dose on recovery4. Balanced fluids or saline

Invited Presenter

Jun International Conference on Intensive Care: Acute Renal Failure in the ICU

Paris, France

Bellomo R 1. Renal replacement therapy: an overview2. Importance of high cut-off membranes in sepsis3. Dialysis dose4. Long-term outcome

Invited Presenter

Jun International congress on ECMO and short-term circulatory/respiratory support

Paris, France

Schmidt M 1. Cardiogenic shock in AMI patients: Outcomes and outcome prediction

2. How to decrease the burden of ECMO-related infections?

3. Setting mechanical ventilation in ARDS patients during VV-ECMO: where are we?

4. Quality of life support: Outcomes after adult ECMO

Invited Presenter

Jun SMACC: Social Media and Critical Care

Chicago, USA

Myburgh JA 1. Forgotten physiology2. PRO: ICP monitoring in TBI is so last season

Invited Presenter

Jul 6th ANZICS-CTG Annual Winter Research Forum

Gold Coast, Australia

Hodgson C 1. Long term outcomes following ICU - the ANZICS CTG Working Party plan for future directions

2. TEAM Multi-centre Phase III RCT

Invited Presenter

Jul 9th Alfred ICU Advanced Mechanical Ventilation Conference


Eastwood G Conservative oxygen therapy: its role in weaning Invited Presenter

Jul ANZICS Clinical Trials Group Annual Winter Research Forum


Eastwood G Physiological monitoring and alarm limits for intensive care patients: a point prevalence study of practice in Australia and New Zealand

Jul ANZICS Safety and Quality Conference: The Deteriorating Patient


Bucknall T 1. Epidemiology of Deteriorating Patients in a Private Hospital

2. Understanding Patient and Family Roles in Triggering Responses to Medical Emergencies

Invited Presenter



Jones D 1. Rapid Response Teams in Australia2. Rapid Response Team Training: The Concept of Roles

and Goals

Convenor and Presenter



Pilcher D Predicting the Need for Medical Emergency Response in Patients Discharged from ICU at the Alfred Hospital

Invited Presenter



Tiruvoipati R Clinical Consequences of Delayed Discharge from Intensive Care: A Multicentre Prospective Observational Study

Invited Presenter

Jul ANZ Intensive Care Society Clinical Trials Group Winter Research Forum


Webb S Short PeRiod IncideNce sTudy of Severe Acute Respiratory Infection

Invited Presenter


Jul Critical Care Society of Southern Africa Congress

Sun City, South Africa

Bellomo R 1. Lessons learned from EGDT trials: where to from here? 2. BLING trial: what’s in the pipeline? 3. Septic acute kidney injury? 4. Fluid bolus for oliguria

Invited Presenter

Jul Patient Reported Outcomes Meeting


Hodgson C Patient Reported Outcomes Following Critical Illness Invited Presenter

Jul Transfusion Outcomes Research Collaborative Annual Investigators’ Meeting


Cooper DJ, McQuilten Z

BLOOD CRE and TRANSFUSE-Iron sub study Invited Presenters

Aug 12th Congress of the World Federation of Societies of Intensive and Critical Care Medicine

Seoul, South Korea

Myburgh JA 1. Management of intracranial hypertension in traumatic brain injury

2. Fluid resuscitation in critically ill patients3. Report of the End of Life Care Task Force of the World

Federation of Societies of Intensive and Critical Care Medicine

Invited Presenter

Aug 12th Congress of the World Federation of Societies of Intensive and Critical Care Medicine

Seoul, South Korea

Bellomo R 1. Septic acute kidney injury2. Do rapid response teams make a difference: the

evidence3. Rapid response systems: the impact of delayed

activation4. The impact of rapid response teams on do not

resuscitate orders

Invited Presenter

Aug ANZCA Clinical Trials Network Strategic Research Workshop

Sanctuary Cove, Australia

Parke R Participant retention and protocol adherence Invited Presenter

Aug Perfusion Down Under Meeting Barossa Valley, Australia

Bellomo R 1. Challenging anticoagulation during ECMO2. Do diagnostic methods for AKI after cardiac surgery

allow early intervention?3. Continuous extracorporeal splanchnic support

Invited Presenter

Sep Australasian Trauma Society Annual Scientific Meeting


Reade M 1. Management of traumatic cardiac arrest2. The PATCH-Trauma trial

Invited Presenter

Sep Chinese Critical Care Congress China Webb S 1. Half of what we do in ICU is wrong; we just don’t know which half

2. Early Goal Directed Therapy: What did we learn from the big trials

3. Physiological targets in ICU – hitting the sweet spot

Plenary Speaker

Sep Chinese Society of Critical Care Medicine Annual Scientific Meeting

FuZhou, China

Myburgh JA 1. What does the ICP tell us about traumatic brain injury?

2. Haemodynamic resuscitation: integrating physiology and evidence

3. Steroids for septic shock: the case for a definitive trial

Invited Presenter

Sep Transfusion Outcomes Research Collaborative Seminar


Cooper DJ Answers and more questions from phase III age of blood and fluid resuscitation trials in the critically ill

Invited Presenter

Oct 40th ANZICS / ACCCN Intensive Care Annual Scientific Meeting (ASM)

Auckland, New Zealand

Eastwood G

1. Cerebral Oxygenation in Mechanically Ventilated Early Cardiac Arrest Survivors: The Impact of Hypercapnia

2. Conservative Oxygen Therapy in Mechanically Ventilated Patients following Cardiac Arrest: A Retrospective Nested Cohort Study

3. The Carbon Control following Cardiac Arrest Trial4. Patterns and Mechanisms of Artificial Kidney Failure

During Continuous Renal Replacement Therapy

Invited Presenter

Oct 40th ANZICS / ACCCN Intensive Care ASM


Glassford N 1. Characteristics and Expectations of Fluid Bolus Therapy: A Worldwide Survey of Intensive Care Clinicians

2. Changes in the Use of Intravenous Fluids in Australia and New Zealand

Invited Presenter

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Hodgson C 1. A Pilot Randomised Controlled Trial of Early Goal Directed Mobilisation IN ICU (TEAM Pilot RCT results)

2. Physiotherapy in ICU: Non-Invasive Ventilation in ICU - current evidence

3. Long Term Outcomes Following ICU

Allied Health Key Note Speaker



Huckson S How To Get Engaged with CORE? Invited Presenter



Iwashyna J 1. How Patients Move from Acute to Persistent Illness

2. Making RCTs Useful - The Role of Heterogeneity3. JAMAgeddon - The Global Journal Club

Showdown, Panel with Chiche JD, Gattas D)4. The Patients as Partners Programme

Invited Presenter



McArthur C 1. Taking the Global View. What networks bind us together across the globe? Are we all the same? (Chair)

2. ANZICS CTG Session (Co-Chair with Parke R)3. Best Medical Paper (Chair)

Chair



Orford N 1. Changing the Way We Work (Panel with Opdam H, Haines K, Schoenbergerorgad M, Modra L, Chamberlain D)

2. JAMAgeddon - The Global Journal Club Showdown (Co-Chair with Parke R)

3. FoamEd The CritIQ View4. Antivirals - Can They Save Us From Apocalypse?

Panel Member



Pilcher DV 1. ARCTIC – How do you know if your cardiac surgeon is any good?

2. ANZICS CORE Outlier Management Program

Invited Presenter





Parke R 1. The Avoidance of Hyperoxaemia during Cardiopulmonary Bypass: A MultiCentre Phase IIb Randomized Controlled Trial

2. JAMAgeddon - The Global Journal Club Showdown (Co-Chair with Orford N)

3. ANZICS CTG Session (Co-Chair with McArthur C4. Writing Critical Care Nursing Publications and

Disseminating Good Practice: Oral and Poster - the Strength of Each

5. Clinical Research vs Quality Improvement – How Do I Know the Difference and Does it Make a Difference?

Invited Presenter and Chair



Presneill J EPO-TBI: Erythropoietin in Traumatic Brain Injury RCT Results

Invited Presenter



Tiruvoipati R Early Experience of Low Flow Extracorporeal Carbon dioxide Removal in Management of Acute Hypercapnic Respiratory Failure

Invited Presenter



Tramm R 1. The Landscape of ECMO Survivorship: A One Year Observational Cohort Study

2. More Questions to Answer - Cognitive Impairment in the Year After ECMO

Invited Presenter



van Lint A Understanding the ANZICS registries: What’s Inside the ANZICS CORE Mystery Box – the New Reporting Portal (with Alexander J)

Invited Presenter



Webb S 1. Integrating Research into Your Clinical Practice2. International Forum of Acute Care Trialists -

Stitching Together the Science

Invited Presenter

Oct Australian Clinical Trials Alliance International Clinical Trials Symposium

Sydney, Australia

Webb S Pushing or Pulling across the evidence-practice gap Invited Presenter

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Conferences and Courses

Prato, Italy 15-17 June 2015In 2015, the ANZIC-RC hosted the 2nd Collaborative Clinical Trials in Intensive Care Medicine Conference in Prato, Italy, with invited attendees from more than 15 countries.

The Conference took place at Monash University’s Prato Centre in the elegant Salone Grollo of the Palazzo Vaj. The Prato conference provided a unique opportunity for participants to engage with internationally renowned leaders in intensive care medicine clinical trials. Presentations covered six main themes: clinical trials in ICU recovery, ventilation strategies for acute lung injury, blood transfusion, extracorporeal membrane oxygenation (ECMO), traumatic brain injury and septic shock. Highlighted were 11 pivotal trials published recently or due for completion over the next 12 months.

Collaborative Clinical Trials in Intensive Care Medicine Conference

The Fine Art of Clinical Trials Course


Oct Australian Military Medical Association Conference

Hobart, Australia

Reade M 1. ADF Trauma Clinical Practice Guidelines – about time?

2. Application of clinical governance in the Role 2E environment: the 2nd General Health Battalion experience

Invited Presenter

Oct Basil Hetzel Institute for Translational Research Annual Research Day

Adelaide, Australia

Webb S Pushing or Pulling across the evidence-practice gap Plenary Speaker

Oct Cochrane Colloquium Vienna, Austria

Synnot A Living Cochrane Reviews: Now, later or never? (Workshop)

Co-facilitator

Oct Ether Day Conference Doha, Qatar

Myburgh JA 1. Neurocritical care and outcome2. Cerebral vasospasm – recent advances3. Normal saline is not normal

Invited Presenter

Oct European Society of Intensive Care Medicine (ESICM) 28th Annual Congress LIVES 2015

Berlin, Germany

French C EPO-TBI Results (presented during the HOT TOPICS session at LIVES 2015 and published simultaneously in The Lancet)

Invited Presenter

Oct HAA Annual Conference Adelaide, Australia

Flint A Epidemiology of platelet transfusions in critically ill patients

Invited Presenter

Oct Intensive Care Foundation Masterclass – Strategies to improve outcomes in ICU


Eastwood G Oxygen Targets: The Sweet Spot Invited Presenter

Oct International Society for Organ Donation and Procurement (ISODP)

Seoul, South Korea

Pilcher DV 1. What is the maximum potential for donation after circulatory death in Australia?

2. Predicting the number of organ donors in Australian hospitals - Implications for monitoring organ donation practices

Invited Presenter

Oct Population Health Congress Hobart, Australia

Tramm R Recovery of critically ill patients treated with extracorporeal membrane oxygenation (ECMO) one year after discharge

Invited Presenter

Oct South Australia Health and Medical Research Institute Scientific Symposium

Adelaide, Australia

Webb S Big Data Needs Randomisation, Randomisation Needs Big Data

Invited Presenter

Nov ANU Medical Research Workshop

Canberra, Australia

Cooper DJ Plenary Lecture: Clinician Scientist Perspective on Medical Research and Grant Strategies

Invited Plenary Presenter

Nov International Consensus Conference on Defining Persistent Critical Illness

Web-conference / Melbourne, Australia

Bellomo R, Cooper DJ, Hodgson C, Iwashyna T

Defining Persistent Critical Illness Invited Panel Members

Dec APSA/ASCEPT Joint Scientific Meeting – Drugs to medicines: up close and personal

Hobart, Australia

Udy A Augmented Renal Clearance: effects on drug disposition and clinical response

Invited Presenter

Dec Intensive Care Society London, UK

Hodgson C 1. A year in review: mechanical ventilation2. PHARLAP RCT3. Early mobilisation - current evidence and

controversies

Invited Presenter

Dec State of the Art Meeting, UK Intensive Care Society

London, UK

Bellomo R 1. Paracetamol in sepsis2. Paradigms, Dogmas and evidence in critical

care3. AKI – does it kill you?4. Masterclass in AKI5. The truth about lactate6. Medical Emergency Teams

Invited Presenter

Barrow Neurological Institute Phoenix, USA

Morganti-Kossmann C

The role of LPA in traumatic brain injury Invited Presenter

Symposium on traumatic brain injury, Karolinska University Hospital

Stockholm, Sweden

Morganti-Kossmann C

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid in patients with traumatic brain injury

Invited Presenter

Prato, Italy 18-19 June 2015In June 2015, the ANZIC-RC hosted The Fine Art of Clinical Trials Course also at the Monash University Centre in Prato, Italy, with participants from 7 countries.

Australian and New Zealand Intensive Care Research Centre

The Alfred CentreLevel 6, 99 Commercial Road

Melbourne, Victoria, Australia 3004

anzicrc.monash.org

Australian and New Zealand Intensive Care Research Centre ...

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