1 3/28/2010

Audrey’s Life Science Meeting Picks for March –May 2010 (Audreysnetwork.com March 26th Edition)

***************************************************************

Optivia Transporter Webinar, Monday Morning, March 29, 2010 Topic: “Transporters for the FDA, DDI and Drug Discovery” Moderator: Dr. Michael Silber, Professor and Chief of Drug Discovery R&D, UCSF, formerly Roche, J&J and Pfizer Panelists: Dr. Les Benet, UCSF, Professor, ITC member Dr. Peter Milner, President, ARYx Therapeutics Dr. Xiaoxiong "Jim" Wei, Director, Clinical Pharmacology, Medpace, formerly FDA (CDER) reviewer. (weijim@yahoo.com, 1-513-579-9911 ext 2147) Dr. Cuiping "Tracy" Chen, Sr. Director, DMPK, Depomed Dr. Caroline Lee, Research Fellow, DMPK, Pfizer and ITC member Dr. Dallas Bednarczyk, Principal Scientist and Study Director, Optivia Date and Time: Monday, March 29, 2010, 10:00 AM (Pacific) / 1:00 PM (Eastern) / 18:00 (UK) / 19:00 (CET) / 2:00 AM (Tokyo) Free registration: https://www2.gotomeeting.com/register/686393218 Topic Description Please attend our panel discussion on the use of transporters in drug discovery and development by experts with experience at the FDA, pharma and academia. Topics include: * Transporters in drug discovery and development. * The recent Transporter White Paper from the ITC (FDA, pharma, academia) and the 2006 FDA draft Guidance on DDI. * Strategies for in vitro transporter studies. * Q&A Panelists: Experts from pharma, academia and former FDA CDER reviewer, including ITC Transporter White Paper authors (see below for details). Who Would Benefit: * Drug discovery and development management * Drug discovery and development scientists * Government Agency scientists * Regulatory professionals * Consultants

Additional Information:

2 3/28/2010

The Transporter White Paper from the ITC (FDA, pharma, academia) was published recently in Nature Reviews - Drug Discovery. The ITC consists of members from the FDA, pharma and academia. The white paper states that it is intended to be used in conjunction with the 2006 FDA draft Guidance on DDI.

The Transporter White Paper and a brief Road Map summary are available at OptiviaBio.net/whitepaper.html. The Road Map summarizes key sections and serves as an index to quickly navigate to them in the White Paper. **********************************************************************

Bio2Device Group, Tuesday Morning, March 30, 2010 Topic: “Product Life Cycle Management in Medical Devices” Speaker: Barbara Sue (Susie) Faries, MBA, CEO, SciMed Partners Inc. Date and Time: Tuesday, March 30, 2010, 8:30 – 10:30 am Location: Sunnyvale City Council Chambers, 456 W. Olive, Sunnyvale, CA (across the street from Sunnyvale Public Library) Cost: Free Parking: On street and in NOVA and library parking lots across the street.

Topic Description Experience has shown that effective life cycle management (LCM) is critical to maintaining customer satisfaction, while minimizing waste and expense. This presentation guides attendees through the critical moments of the medical life cycle, beginning with the introduction of a new product, the "maintenance" of the product during its core lifetime, and finally, the obsolescence and likely replacement of the product in the field. The presentation covers: • Definition of life cycle management • Required coordination of multiple departments • How customer focus is the first requirement • Roles of involved departments • Implementation of effective life cycle management

Speaker Bio Ms. Faries is CEO of SciMed Partners. SciMed, headquartered in the Bay Area, helps established companies, potential investors, and entrepreneurs assess markets, technologies, and intellectual property in the scientific and medical arenas. SciMed focuses on medical devices, medicine, biotechnology, pharmaceuticals, and emerging technologies. “Susie” has held senior executive level positions with major US corporations including Vice President of Marketing for American Medical Response, the largest provider of emergency medical services in the US ($1 billion in revenue) and Vice President of Marketing for American Medical Pathways, the technology subsidiary of American Medical Response. She has worked in large and start-up environments in medical devices and health care technologies. She is the former CEO of SMS Healthcare, headquartered first in Virginia then Denver, with offices in North Carolina and West Virginia. She comes from a family of entrepreneurs that has an 89-year track record of successful business operations.

3 3/28/2010

**********************************************************

San Jose State University Biomedical Engineering Society, Tuesday, March 30, 2010

Event: Bay Area Biomedical Device Conference 2010

Speakers: • Julian Nikolchev, Founder & CEO, Pivot, Inc. • Rob Abrams, Operating Partner, Sanderling Ventures • Tom Bauer, M.D., Ph.D., The Cleveland Clinic Foundation • Larry Eiselstein, Ph.D, P.E., Exponent, Inc. • Raj Makkar, M.D., Ph.D., Cedars’ Sinai Medical Center • Jeffrey Lotz, M.D., Ph.D., Professor, University of California, San Francisco

Date and Time: Tuesday, March 30, 2010, 8:00 am – 5:00 pm Location: Engineering Auditorium at SJSU For details and on-line registration, go to: http://www.engr.sjsu.edu/bmes/2010Conference.html Cost:

• $195 Early Registration • $245 Late Registration (After 3/17/2009) • $275 Walk in registration • $40 SJSU Students • $75 Non-SJSU Students

Event Description The Organizing Committee has identified and invited a set of outstanding speakers who will address several areas that are critical to the biomedical device industry. There will be presentations on interventional cardiology, device explants, corrosion of implants, intervertebral disc degeneration and regeneration, appropriate selection of animal models for clinical trials, regulatory affairs and entrepreneurship pertaining to medical devices. This event will not only cover technologically significant advances in the field, but will also serve as a networking opportunity.

**********************************************************************

MD&DI Free Webinar, Tuesday Morning, March 30, 2010 Topic: Technology Trends: The Quest for Innovation

Panelists for the Webcast include: Larry Schmitt, President and Founder,Inovo

John Bashkin,VP strategic business development,Triple Ring Technologies ( Newark, CA) Jim Best, Founding Partner and Principle,Pensa Moderated by: Heather Thompson, Managing editor,MD&DI

Date and Time: March 30, 2010, 11:00 am – noon PT Cost: Free Register at: https://event.on24.com/eventRegistration/EventLobbyServlet?target=registration.jsp&eventid=198749&sessionid=1&key=19E071BDB939D0A92ADA3D77A44F5830&partnerref=mddionline&sourcepage=register

4 3/28/2010

Topic Description What does it mean to be innovative? How can medical device manufacturers adopt innovation programs to create successful products? This Webcast seeks to provide answers by exploring available innovation models that are currently in use in this and other industries. Experts provide the latest ideas in developing and creating medical devices using such models. They also explore avoiding common pitfalls and how to implement an innovation model into a busy lifecycle process. See details at http://www.mddionline.com/webcasts Note you can view this webcast at later time by returning to website. See replay of excellent Topic: “The Medtech Marketplace in 2010” Moderated by:Sherrie Conroy, Director of Content, Medical Device Brands Topics and Speakers:

• “New Product Development & Launch Strategies - The Next Era in Medtech, ”Rebekkah Carney, MIM, Associate Vice President, MedSurg Insight, GfK Healthcare

• Topic: “Transactions in the Medtech Space,” John L. Babbit, Transaction Advisory Services, Ernst & Young

****************************************************************

Free UCSC Extension Bioscience Program, Tuesday Evening, March 30, 2010

Topic: Bioscience Program Information and Q&A Session

Instructor: Michelle Ragozzino, Ph.D., Program Director Date and Time: Tuesday, March 30, 2010, 6:30 – 8:00 pm Location: 2505 Augustine Drive, Santa Clara, CA Cost: No fee but enrollment required Register at www.ucsc-extension.edu

Course Description:

This free evening event is an informal discussion geared towards new or returning students interested in one or more of the Bioscience certificate programs. Led by the director of the Bioscience programs, the event begins with a short overview of the five Bioscience certificates, followed by an open-floor segment for audience questions. *************************************************************** BioDesign, Tuesday Evening, March 30, 2010 Topic: From the Innovator’s Workbench

Speaker: Lonnie Smith, Chairman of the Board and Chief Executive Officer, Intuitive Surgical, Palo Alto, CA

Date and Time: Tuesday, March 30, 2010, 5:30-6:30 pm with reception to follow Location: Vidalakis Dining Room, Schwab Res Ctr, Stanford Graduate School of Business (see http://biodesign.stanford.edu/bdn/networking/workbench.jsp#parking about parking) Stanford faculty, students and staff: To register, send an email to biodesign@stanford.edu from your Stanford email account. For all others, register at http://www.certain.com/system/profile/form/index.cfm?PKformID=0x8779157fbb

5 3/28/2010

General Admission $ 45.00 Limit: 80 Available: 44

Stanford Alumni $ 35.00 Limit: 60 Available: 42

Topic Description

From the Innovator's Workbench

From the Innovator's Workbench features top innovators in the biomedical technology field, interviewed by David Cassak. In this series you'll hear them discuss their process of

• identifying major critical needs • creating new technologies • implementing innovations in patient care

The Workbench events serve several purposes, first, to showcase the people who have built the industry and expose the community to their story and lessons learned. In addition, we seek to provide a networking opportunity for the medical device community. There is an opportunity following the interview to network with others in the field: VCs, attorneys, industry professionals.

Speaker Bio

Mr. Smith joined Intuitive in June 1997 from Hillenbrand Industries, where he was Senior Executive Vice President. Mr. Smith joined Hillenbrand in 1978 and during his tenure he was also a member of the executive committee, the office of the president and the board of directors. Mr. Smith has also held positions with The Boston Consulting Group and IBM. Mr. Smith received his BSEE from Utah State University and an MBA from Harvard Business School.

************************************************************ *****************************************************************

The Visibility Solution: Delivering an Accurate View of Clinical Operations Thursday, April 1st at 11:00am ET / 16:00 GMT

Register Free at www.pharmexec.com/visibility

Event Overview: Attend this Web seminar to understand how pharmaceutical manufacturers can obtain a clear and consistent view of clinical-trial progress and costs through effective data governance - providing a platform for future growth.

Key Learning Objectives:

Presenters:

John Evans Director of Product Marketing Kalido

Bill Wallace Solution Architect HighPoint Solutions

6 3/28/2010

• Reduce the risk of clinical programs by reducing the time to make informed decisions

• Increase the accuracy and timeliness of clinical and operational data to support decision-making across the organization

• Integrate data from disparate systems and sources to increase visibility across operations and studies

Who Should Attend:

• Corporate Management (President, CEO, CFO, COO, SVP, VP)

• Product/Brand Management (including Director/Group Mgr)

• Marketing Management (including Director/Group Mgr)

• R&D, QA/QC Management • Medical/Clinical Management • Information Technology

For more information contact Jamie Carpenter at jcarpenter@advanstar.com or 1-440-891-2725.

Moderator:

William Looney Editor in Chief Pharmaceutical Executive Magazine

********************************************************************* Science/UCSF Biotech Career Day, Wednesday, April 1, 2010 Event: Science/UCSF Biotech Industry Career Day

Date and Time: Wednesday, April 1, 2010, Workshops: 10:00 a.m. - 4:00 p.m. Recruiters available: 1:00 p.m. - 4:30 p.m

Location: UCSF Mission Bay Campus - Genentech Hall, 600 16th Street, San Francisco, CA

Cost: Free to attendees; open to all; no registration required Visit the Mission Bay campus for a chance to get valuable advice from career experts and to meet face to face with recruiters from some of the world's top scientific organizations. Don't miss this opportunity to connect with staffing professionals and hiring managers from the companies you want to work for. Science and UCSF are teaming up to bring you a unique biotech day that includes five career development workshops and a chance to meet face to face with recruiters. Details at http://sciencecareers.sciencemag.org/ucsf Workshops:

• Industry Career Paths - 10:00 a.m. - 11:30 a.m. (Brianna Blaser, Project Director for Outreach, Science Careers/AAAS, and panel) Join us for a panel discussion with Ph.D.-level scientists who work in industry. Bring your questions to learn more about the opportunities in industry, the skills needed to succeed, and how to transition to your first year on the job.

7 3/28/2010

• Transitional Education/Training for Alternative Careers in Science - 11:45 a.m. - 12:45 p.m. (Victoria Sharma, Program Director for Bioscience, UC Berkeley Extension) Transitioning to a new career can be daunting, but getting the latest up-to-date training can give you a leg up on the competition. Explore new training options for various bioscience careers such as clinical and regulatory sciences and biopharmaceutical business.

• Making Connections: Networking and Career Fairs - 1:00 p.m. - 2:00 p.m. (Brianna Blaser, Project Director for Outreach, Science Careers/AAAS) This presentation will teach you the basics of good networking and how to employ those tactics in a career fair setting. Strategize about how to make the most of a career fair, how to introduce yourself, and what to do after the event is over. Using the techniques you learn will help you make the most of the career fair.

• Job Hunting in the Biotech Industry - 2:15 p.m. - 3:30 p.m. (Bill Lindstaedt, Director, Office of Career and Professional Development, UCSF) Learn how to prepare resumes and cover letters for your industry job search. Also, you will learn about job search strategies necessary for success on the biotech/pharma job market along with some tips for interview success and effective negotiations after you receive your job offer. After this seminar you will understand how to apply the four job hunting techniques that comprise a comprehensive job search in the biotech industry.

• Q&A: An Open Forum with UCSF Career Counselors - 3:30 p.m. - 4:00 p.m.

How to Prepare for the Career Event You will need to bring several copies of your resume/CV for recruiters who may request them. Read Making the Most of Career Fairs for good advice.

**************************************************************

Triple Ring Technologies, MedTech Frontiers, Wednesday Evening, April 1, 2010

Topic: “The Role of Medical Robotics in the Treatment from Cancer to Hair Transplantation” Speaker: Dr. Mohan Bodduluri, Co-Founder and VP of R&D, Restoration Robotics Date and Time: April 1 2010; 6:00 – 6:45 PM Refreshments 6:45 – 8:00 PM Presentation & Questions 8:00 – 9:00 PM Networking & Consultations Location: Triple Ring Technologies, Inc. 39655 Eureka Drive Newark, CA 94560 (510) 592-3000 Cost: Free but registration is required. Go to http://contactbeacon.com/cb/prefs/reg.php?id=33713bf7-c76e-4e4a-8d2a-32ecc8224779 Topic Description The event on April 1 will feature Dr. Mohan Bodduluri, co-founder and VP of R&D at Restoration Robotics. Dr. Bodduluri was previously VP of R&D at Accuray, where he helped develop the Cyberknife system. His presentation will focus on various technologies, such as image processing, machine vision, and robotics, that have to come together to be effective in the highly regulated field of medical devices.

8 3/28/2010

In particular, the talk will focus on the two companies the speaker has been involved in, Restoration Robotics and Accuray.

*****************************************************************

Northern California Chapter, ACRP, Thursday Evening, April 1, 2010 Topic: “Top Ten Intellectual Optical Illusions in Clinical Research” Speaker: Richard Chin, M.D, CEO Institute of One World Health, San Francisco, CA Date and Time: Thursday April 1, 2010 6:00 – 9:00 pm Agenda: 6:00 – 7:00 PM Registration sign-in, Networking, & Dinner Buffet 7:00 – 7:30 PM Welcome, Announcements, "OPEN MIC" for job referrals 7:30 – 8:45 PM Educational Program 8.45 – 9.00 PM Q&A Location: The Institute for One World Health, 50 California Street, Suite 500, San Francisco, CA 94111 Cost:

NCC ACRP member Free

ACRP member $10 Non-member $15

See further about contact hours, etc. and other details at EVENT REGISTRATION before Monday, 29 March 2010 11:59PM PST Register early to assure admission; at event IF space available (+$5.00 nonmember) REGISTER? NOW – or click http://www.acrpnet.org Northern CA Chapter Topic Description As recent work by Kahneman have demonstrated, there are certain cognitive shortcuts that human brain takes when examining data and making decisions. Clinical trial results are particularly prone to such "intellectual optical illusions" because primate brains are not hardwired to interpret large amounts of aggregate statistical data. This lecture will explain some of the most common mistakes in clinical trial interpretations such as regression to the mean, subgroup analysis based on dependent variables, and common paradoxes in clinical data. Speaker Bio Richard Chin received a B.A. in Biology, magna cum laude, from Harvard University and the equivalent of a J.D. with honors from Oxford University in England under a Rhodes Scholarship. Dr. Chin holds a Medical Degree from Harvard Medical School and is licensed to practice medicine in California. He previously served on the Adjunct Clinical Faculty of Stanford University School of Medicine and currently serves on the Boards of Directors of RXi Pharmaceuticals, a company founded by Craig Mello developing novel RNAi based treatments for human diseases, and of Genmedica Therapeutics, a leading biotech company in Spain developing innovative treatments for diabetes. Dr. Chin joins One World Health from OXiGENE, where he served as President and Chief Executive Officer. Previously, Dr. Chin served as Senior Vice President and Head of Global Development for Elan Corporation, where he had worldwide responsibility for Clinical Development, Regulatory, Biostatistics, CMC, QA/Compliance, Safety and Medical Affairs. Dr. Chin has also held various clinical and scientific roles for Genentech, Inc. including Head of Clinical Research for the Biotherapeutics Unit, overseeing approximately half of the drugs at Genentech, and began his career at Procter and

9 3/28/2010

Gamble Pharmaceuticals, where he served as Associate Medical Director. Richard Chin, M.D. Chief Executive Officer, is an Internist with extensive expertise in drug development. He has overseen over 40 Investigational New Drug (IND) Applications for new molecular entities and new indications, as well as eight New Drug Applications (NDAs)/Biologic License Applications (BLAs), and has authored a major textbook on clinical trial medicine. Program Objectives:

Understand regression to the mean Understand proper use of p value Understand pitfalls of subgroup analysis

Target Audience: Clinical Research Professionals Sponsor Organizations Study Site Investigators & Coordinators Independent Consultants Students of Clinical Research Academic Medical/Clinical Researchers Service Providers/Vendors Institutional Review Boards Quality Assurance

**************************************************************

Free Pharmaceutical Executive Webinar, Thursday Morning, April 1, 2010

Topic: “The Visibility Solution: Delivering an Accurate View of Clinical Operations” Moderator: William Looney, Editor in Chief Pharmaceutical Executive Magazine Presenters: Bill Wallace,Solution Architect, HighPoint Solutions John Evans, Director of Product Marketing, Kalido Date and Time: Thursday, April 1st at 8:00 am PT Register Free at www.pharmexec.com/visibility Event Overview: Attend this Web seminar to understand how pharmaceutical manufacturers can obtain a clear and consistent view of clinical-trial progress and costs through effective data governance - providing a platform for future growth. Key Learning Objectives:

• Reduce the risk of clinical programs by reducing the time to make informed decisions

• Increase the accuracy and timeliness of clinical and operational data to support decision-making across the organization

• Integrate data from disparate systems and sources to increase visibility across operations and studies

Who Should Attend: • Corporate Management (President, CEO, CFO, COO, SVP, VP) • Product/Brand Management (including Director/Group Mgr) • Marketing Management (including Director/Group Mgr) • R&D, QA/QC Management

10 3/28/2010

• Medical/Clinical Management • Information Technology

For more information contact Jamie Carpenter at jcarpenter@advanstar.com or 1-440-891-2725.

*******************************************************

FountainBlue, Friday Morning, April 2, 2010 Topic:” FountainBlue's Funding Road Trip: Perfecting Your Pitch to Investors” Speaker: Bill Joos, principal of "Go To Market Consulting Date and Time: Friday, April 2, 8:30 a.m. - 1:00 p.m. 8:30 Registration and Networking, in the Cooley Café 9:00 Bill Joos: Perfecting Your Pitch to Investors, in the Cooley Café 10:30 Morning Break 10:45 Pitch Practice Sessions - 15 mins a team 1:00 Optional Pitch Debrief Meeting 1:30 Adjourn. Please note that we have the room until 1:45 p.m. and we welcome you to stay to network with fellow entrepreneurs. Location: Cooley Godward Kronish LLP, 3175 Hanover, Palo Alto Audience: Early-Stage, Funding-Bound Clean Energy, High Tech and Life Science Entrepreneurs and Intrapreneurs, who have attended our October and/or our November workshops Cost for 1 or 2 Entrepreneurs: $83 for FountainBlue members, $93 for Partners, $103 General On-Site for members is $103 and $124 and for non-members. Registration: Please pre-register by noon on 3/31 using the PayPal link at http://www.fountainblue.biz/fundingroadtrip.html. Topic Description FountainBlue cordially invites high tech, life science and clean energy entrepreneurs to the second funding preparation workshop entitled 'Perfecting Your Pitch to Investors'. This hands-on workshop, which follows the first workshop entitled 'Your Company's Value Proposition', will take entrepreneurs through the process of creating and delivering a compelling elevator pitch, a one-page executive summary and a 13-15 slide company overview presentation. Attendance at one of the two workshops in the series is a pre-requisite to attending our third and final workshop in the series, 'Your Meeting with Investors', which features feedback from active investors. For this workshop, working in partnership with fellow entrepreneurs in similar, non-competing spaces, participating entrepreneurs will have the opportunity to learn best practices and immediately apply these learnings to their own companies. Whether you are a serial entrepreneur, or someone who may be considering a future opportunity, you are sure to benefit from the information presented, the connections made and the peer-to-peer knowledge shared. Speaker Bio Bill Joos is the principal of "Go To Market Consulting", based in Palo Alto, CA. He works with early stage startups, venture capital firms and their portfolio clients. Most recently he spent 6 years as the VP of Entrepreneur Development at Garage Technology

11 3/28/2010

Ventures, an early stage venture capital firm that he co-founded along with Guy Kawasaki. His reputation at Garage was that he provided their clients with effective, hands-on, action-oriented strategic and tactical mentoring and coaching. Bill has worked with literally hundreds of early-to-mid stage startups and helped them polish and clarify their messages and refine their fund-raising and customer presentations; but his contributions to them extended well beyond being a "Pitch Doctor". He has mentored and coached them in go to market strategies, revenue and pricing optimization, business alliances, business development, partnerships, and marketing. Over 15,000 entrepreneurs worldwide have attended conferences where Bill has been a featured keynote speaker on various entrepreneurial topics. He has held sales and marketing positions with a variety of companies, including IBM and as a VP of the software division of Apple Computer.

*******************************************************************

Bio2Device Group, Tuesday Morning, April 6, 2010

Topic: “Self-guided Surgery” Speaker: John Black, Ph.D., VP, Imaging, Avinger Inc. Date and Time: Tuesday, March 16, 2010, 8:30 – 10:30 am Location: Sunnyvale City Council Chambers, 456 W. Olive, Sunnyvale, CA (across the street from Sunnyvale Public Library) Cost: Free Parking: On street and in NOVA and library parking lots across the street. Topic Description The introduction of the laser as a therapeutic surgical tool in the 1960's has had a profound effect on certain fields of medicine, particularly in ophthalmology and more recently in minimally invasive surgical disciplines such as urology. The use of laser-based optical diagnostic tools, both as stand-alone devices and coupled to other instruments has recently started to blossom as many of the advances in electronics, computing and optical telecommunications of the last decade make their way into the biophotonics field. The enabling features of light-based diagnostics include the ability to use fiber-optics, sometimes with outer diameters as small as 50 microns as conduits for information, the extremely high intrinsic bandwidths and signal-to-noise of optical systems, and the possibility of using both the spectral and coherence properties of laser light to yield simultaneously both functional (molecular level) and structural (tissue organization) information. John will present a tour of how optical techniques available today can be used to sense temperature, pH, and force, and show how the optical analog of ultrasound, Optical Coherence Tomography, is being used to equip surgical instruments with the ability to allow the physician to image the tissue they are interacting with and to make a treatment decision in real time, with 10-micron precision, all with minimal mechanical and cost impact on the surgical tool. Examples from thermal coagulation (ablation) and intravascular plaque excision will be discussed. Speaker Bio: John Black has 16 years of experience in the medical, commercial and research segments of the photonics industry. At Avinger, he leads the engineering effort in the development of image-guided catheters for the treatment of peripheral and coronary artery disease. Prior to Avinger, he led the optical engineering team at FoxHollow Technologies in the successful development of the first-in-man intravascular real-time

12 3/28/2010

image-guided plaque excision catheter (Nighthawk™). http://www.medicalnewstoday.com/articles/51482.php. At Coherent Medical he was the manager of the Laser / Tissue Engineering group spearheading the development of flagship surgical, ophthalmic and dermatologic applications of lasers. While at Coherent he pioneered a new treatment of cutaneous vascular lesions which led to the development of the Cynosure Cynergy™ Vascular Workstation (unfortunately not the Coherent Cynergy Vascular Workstation). Also at Coherent he co-discovered the first laser-activated intravascular blood-pool MRI contrast agent. After Coherent he joined Lightwave Electronics (now JDSU, Inc.) working initially on advanced fiber lasers for RGB projection systems in consumer electronics ( http://www.sony.net/Products/SC-HP/cx_news/vol40/sideview.html), and subsequently on the laser design for the industry-leading Xcyte™ mode-locked ultraviolet laser for flow cytometry. John has a B.Sc. in Chemistry with First Class Honors and a Ph.D. in Physical Chemistry from the University of Nottingham. He received the T.J. King Memorial Prize for undergraduate physical chemistry research and an SERC / NATO Research Fellowship to do post-doctoral research in photochemistry at Stanford University. He was also a post-doctoral research fellow at Columbia University developing new lasers for molecular spectroscopy and reaction dynamics. He has lectured widely both in the US and abroad on laser spectroscopy and applications in medicine, and has several well-cited publications in these areas. John has 4 issued patents and several pending applications in the fields of laser development, trans-dermal cardiac output monitoring, optical diagnostics, and medical devices. He is a Senior Member of the IEEE, and a member of OSA, APS, SPIE and Sigma Xi. He has also been a Guest Lecturer at the University of Arizona Biomedical Engineering Program, and is a peer-reviewer for several high-impact journals including Optics Express, Optics Communications, Lasers in Surgery and Medicine and the Springer “Series in Optical Sciences” books.

********************************************************************

BayBio One-Day Conference, Wednesday, April 7, 2010

Topic: “BayBio2010:Life Science Innovation: Drivers and Barriers” Date and Time: 04/07/2010 - 8:30am – 5:30 pm Location: Hyatt Regency San Francisco Airport: 1333 Bayshore Highway Burlingame, CA. Event Details Event Type:

Regular by April 1st On-Site on April 7th Life Science

Members $475 $575 Life Science

Non-Members $575 $675 Service Provider

Members $575 $675 Service Provider Non-Members $675 $775

Life Sciences Special** Group of 3

Life Sciences Special** Group of 5

13 3/28/2010

** Life Sciences Special is valid through April 1, 2010. Only groups of professionals working for companies engaged in life sciences product research and development qualify for this special. Special applies only to individuals registering from the same life sciences company. Membership is subject to verification and must be active through the day of the conference.

Flat car parking rate: $5.00

Event Description BayBio2010 is a one-day conference focusing on Northern California's strength in life sciences innovation. This conference will examine the fundamental questions of who pays for biotech innovation and why in this unprecedented environment. It will focus on how the current financing environment and new sources of capital affect business models, development and commercialization strategies. In doing so, BayBio2010 will consider government initiatives, such as healthcare reform, clean energy legislation and American Recovery and Reinvestment (ARRA) funding, and effects of these programs on therapeutic, diagnostic and clean tech companies. Additionally, the conference will review new trends in public markets, venture investment, M&A and partnering with larger companies and how they affect the life sciences research and development process. Finally, BayBio2010 will investigate how changing consumer behavior and resulting economic realities factor into biotech company strategies. URL: http://www.baybio.org/wt/page/BayBio2010

******************************************************************

Stanford Center for Law and the Biosciences, Friday, April 9, 2010

Topic: “Drug Development and International Access” Speakers Include: • Gregg Alton, Executive Vice President, Corporate and Medical Affairs at Gilead • Tom Bollyky, Fellow at the Center for Global Development • Robert Chess, Chairman, Nektar Therapeutics; Board member and initial Chairman, Bio Ventures for Global Health • Richard Chin, CEO of OneWorld Health • Joe Damond, Vice President of Government Relations at Pfizer • Charlie Kinzig, Vice President of Corporate Intellectual Property at GlaxoSmithKline • Carol Mimura, Assistant Vice Chancellor, UC Berkeley Intellectual Property & Industry Research Alliances • Jenik Radon, Professor at Columbia University's School of International and Public Affairs • Hannu Wager, Counselor in the IP Division of the WTO, and Secretary of the WTO TRIPS Council Date and Time: Friday, April 9, 2010, 9:00 am – 2:00 pm Location: Stanford Law School Cost: Free This event is free and open to the public. For more information, please contact Kelly Lowenberg at klowenberg@law.stanford.edu or visit the event website. Register at http://www.stanford.edu/dept/law/forms/DrugDev.fb

14 3/28/2010

Topic Description Many life-threatening diseases disproportionally affect people in low-income and middle-income countries. Even when treatments exist, many people are unable to afford essential medicines needed for survival. While patent protection for new medicines is necessary to incentivize drug research and development, in developing countries, these patents prevent price-lowering competition. Professor John Barton, a member of the Stanford Law School faculty for 40 years, devoted the latter part of his distinguished career to increasing access to medicine while continuing to provide incentives for drug development. In 2008, Professor John Barton and Pfizer CEO Jeff Kindler proposed a new international framework on drug pricing, favoring IP exemption for the poorest countries, an international drug approval process, divided markets in middle-income countries, and trade agreements among developed countries to ensure policies recognize and reward innovation. In tribute to Professor Barton's work and his dedication to increasing access to medicine, this conference aims to discuss some of the innovative new business models and intellectual property strategies, including Professor Barton's proposal, which will make it possible for more patients to have access to life-saving medicines. Speakers will discuss business strategies to incentivize research and development, models to reduce the cost of drug development, and intellectual property, regulatory, and pricing structures effecting access to medicine. ********************************************************************

Bio2Device Group, Tuesday Evening, April 13, 2010 Topic: “A Serial Entrepreneur's Journey- How a Physicist became a Leading Device Innovator” Speaker: Hira Thapliyal, Ph.D., President and CEO, VytronUS, Inc. Date and Time: 4/13/2010, 6:00 pm Location: TIPS, 1000 Elwell Ct., Suite 150, Palo Alto, CA Cost: $6 - Students/In-transition - Members only (good through Apr 11th) $11 - Early-bird Registration - Members only (good through Apr 11th) $20 - Late Registration - Members / Non-Members (Apr 12th, 13th) $25 - Walk-ins (after Apr 13th 3PM) Event Registration : http://www.bio2devicegroup.org/content/serial-entrepreneur039s-journey-h\ ow-physicist-became-leading-device-innovator-hira-thapliyal <http://www.bio2devicegroup.org/content/serial-entrepreneur039s-journey-\ how-physicist-became-leading-device-innovator-hira-thapliyal Topic Description Hira Thapliyal will discuss his journey from a physicist to a leading serial entrepreneur in Silicon Valley/USA. He will discuss the highs and lows, and some lessons he has learned along the way. Along his successful career path you will see familiar companies that he has lead and/or founded such as DVI, CVIS, Arthrocare, Tescient, MicroBionics, and VytronUS. Speaker Bio Dr. Hira Thapliyal, Ph.D., got started in the medical device industry while developing a cauterizing, glass scalpel. A cardiovascular industry veteran, who played a critical role in the founding of companies such as atherectomy pioneer DVI (Devices for Vascular Intervention Inc.), and intravascular ultrasound leader CVIS (Cardiovascular Imaging

15 3/28/2010

Systems, now part of Boston Scientific Corp.). Three years later he became CEO of MicroBionics, Inc. Thapliyal then founded a new company in April 1993 called ArthroCare Corporation, which used coblation technology to facilitate arthroscopic joint surgery. Dr. Thapliyal served as the company's initial president and chief executive officer. Hira then co-founded and was CEO of Tescient, Inc. Hira is currently the President & CEO of VytronUS, Inc. VytronUS is developing products in cardiovascular field. Hira is currently a member of the Board of Directors for Apsara Medical, Inc., Intact Medical, Inc., and PAVAD Medical, Inc. He is also the Special Partner of MedVenture Associates IV. Dr. Thapliyal is also an Advisory Board Member to the Department of BioEngineering at University of California, Berkeley and Materials Science and Engineering at Cornell University. Dr. Hira Thapliyal earned his B.S. in electrical engineering from Washington State University, followed by an M.S. in electrical engineering from the University of Idaho and a Ph.D. in materials science and engineering from Cornell University. ********************************************************************** sfAWIS, Wednesday, April 14, 2010 Event: Social Networking Join us April 14th at Bissap Baobab for our next bi-monthly Networking Event. Date and Time: April 14th, 2010, 6:30 to 8:00 pm Cost: Free Location: Bissap Baobab, 3372 19th Street, San Francisco Link to Bissap Baobab

All scientists, students, and friends are welcome. ************************************************************** Bioscience Business and Marketing Essentials, Thursday and Friday, April 15-16, 2010 2-Day Intensive Course: Bioscience Business and Marketing Essentials, Thursday and Friday, April 15-16, 2010 with 2 months to complete project Lead Instructor: Audrey S. Erbes, Ph.D., Principal, Erbes & Associates and www.audreysnetwork.com Expert Guest Speakers: Donald Holsten, Pharm. D., Regulatory Consultant and Educator Bev Hudson, MBA, General Manager, Clinical Research Services, MedPoint

Communications, Inc Julie Tompkins, MBA, Sr. Vice President, Timely Data Resources (TDR)

Please see www.ucsc-extension.edu/biobusiness for complete biographies Date & Time: April 15-15, 2010, Thursday and Friday, 8:30am-5pm Location: UCSC Extension in Silicon Valley, 2505 Augustine Drive, Santa Clara, CA 95053 Fee: $750; $675 through April 1 Topic Description The bioscience industry is like no other. Lengthy timelines and unique financial, legal, regulatory, social and political challenges impose constraints that impact every aspect of the business. This course helps participants gain: a practical understanding of the bioscience industry landscape, key business drivers and challenges; insight into the critical roles that business and marketing disciplines play at all stages of a bioscience company's development; and hands-on experience implementing important bioscience business processes that are essential to success within the industry. Two days of intensive classroom are followed by 2 months to complete individual project with

16 3/28/2010

guidance of instruction and access to research resources. For more information: See www.ucsc-extension.edu/biobusiness. Instructor Bio Audrey Erbes, Ph.D., Principal of Erbes & Associates and www.audreysnetwork.com, is a marketing consultant with more than 30 years of managerial experience in marketing and business development in the biotech and pharmaceutical industries. She was Executive Vice President and cofounder of Kowa Research Institute, a biopharmaceutical licensing and investment subsidiary of Kowa Company Ltd., Japan and before that held management positions at Syntex Corp. in market research, product management, strategic marketing and planning, and business development in the U.S. and abroad.

**********************************************************************

BayBio NEST Venture Spotlight, Thursday Morning, April 15, 2010

Topic: “A Tailor Made Approach: Personalized Medicine” Panel Moderator: Jeff Peterson, CEO, Target Discovery Panel Speakers: Bill Gerber, Bay City Capital Date and Time: April 15th, 2010, 8:00 – 10:00 am Location: Latham & Watkins, Menlo Park Campus, 140 Scott Dr., Menlo Park, CA 94025 Cost: Early Bird Registration through March 13th:$19.00;On-Site Registration, March 15th:$29.00 Register at http://www.acteva.com/booking.cfm?bevaid=195773 (If you are an employee of a Sponsor company, please contact Program Manager, Jessica Knowles to obtain your complimentary registration.)

Topic Description The crisis of health care economics is now frighteningly familiar to us all, driven by advancing technology often coupled with increasing cost. Personalized Medicine is our greatest hope for remediation of this rising economic tsunami. Decades of advances in molecular biology are now delivering important new diagnostics for Personalized Medicine (PMDx) to determine the patient's response, resistance or toxicity risk before or during treatment, in order to optimize the selection of medical treatments from amongst the alternative options. Patients benefit enormously by not wasting valuable months of treatment time and not undergoing the side effects and physical insult of ineffective or toxic treatments like chemotherapy in cancer.

The BayBioNEST Venture Spotlight Series is a unique forum that allows investors to speak directly to entrepreneurs in a reverse pitch format. Investors and experts have a platform to discuss their current interests, target markets, therapies and technologies, as well as the maturation level of investment targets. The Venture Spotlight Series is a breakfast panel discussion with time for Q&A and networking.

******************************************************************

San Jose BioCenter, Thursday Morning, April 15, 2010

Topic: “Effective outsourcing: Navigating hurdles and avoiding pitfalls in virtual drug development” The panel will include:

17 3/28/2010

• Dr. Kate Hanham, President & Founder, Mentara, Inc.: Mentara is a consulting consortium of highly qualified drug/device discovery and development professionals. • Richard Lin, President, Explora Biolabs, Inc.: Explora BioLabs provides vivarium and pre-clinical in vivo contract research services. • Dr. Fred Aslan, Vice President, Venrock: an investor experienced in starting and running virtual companies. • Dr. Michael Chang, Vice President, Research & Development, Limerick BioPharma: an executive using the virtual development model. • Toni Foster, former Senior Director, Clinical and Project Management, Biovascular: an expert with over 17 years of experience and over 45 clinical drug trials managed Date and Time: Thursday, April 15, 2010 | 11:30am-1:30pm Location: The San Jose BioCenter, 5941 Optical Court, San Jose, CA 95138 Space is limited for this event, so early pre-registration is recommended to

avoid disappointment on the day! • Regular Price: $30 • Partners' Network: $20 • BioCenter Members: Free (RSVP to Aurélie) • On-site Registration: add $10 to the above Register at http://www.acteva.com/booking.cfm?bevaid=195685 Topic Description Virtual drug development promises savings of time and cost in the development of new drugs and devices. In order to realize this promise, managers and executives may need to learn some new tricks! In this session a panel of experts with different perspectives on the virtual development experience will discuss some of the advantages and challenges of the virtual model. Virtual drug development promises savings of time and cost in the development of new drugs and devices. In order to realize this promise, managers and executives may need to learn some new tricks! In this session a panel of experts with different perspectives on the virtual development experience will discuss some of the advantages and challenges of the virtual model. ******************************************************* CACO Workshop, Monday Afternoon, April 19, 2010

Date and Time: Monday, April 19, 2010, 12:45 – 5:30 pm Event Topic: Drug Transporters: Interpretation and Application of the International Transporter Consortium Whitepaper and Draft FDA Guidance Speakers: Joseph Polli (GSK), Caroline Lee (Pfizer), Harma Ellens (GSK), Xiaoyan Chu (Merck) Location: Bay Area: Foster City Crowne Plaza Event fee: $1 for unemployed; For others, details available upon online login. Major Sponsor: (1)Qualyst, Inc. Vendor show vendors registered to date: (11)Absorption Systems; Applied Biosystems; BD Gentest; CellzDirect; Celsis In Vitro Technologies; Enthalpy Analytical; MicroConstants, Inc.; Optivia Biotechnology; Quotient Bioresearch; Vitalea Science, Inc.;

18 3/28/2010

XenoTech, LLC Online registration and further details: http://www.caco-ca.org Registration deadline: 4/16/2010 (it will close sooner if the seating cap is reached) Additional Details: www.caco-ca.org

**************************************************************************

FountainBlue Life Science Forum, Monday Evening, April 19, 2010 Topic: “Physician's Panel: Partnering with Entrepreneurs to Better Address Patient Needs” Date & Time: Monday, April 19 from 5:30 - 7:30 p.m. Location: Bay Cafe Clubhouse, 1875 Embarcadero, Palo Alto Cost: $21 members, $32 partners, $42 general On-Site Registration is $42 for members, $52 for nonmembers, or $124 for FountainBlue Ongoing membership and admission Registration: Please pre-register by noon on the Friday prior to the event using the PayPal link at http://www.svlifescience.com. Audience: Life Science entrepreneurs, intrapreneurs and investors, no service providers please Facilitator KPMG to be confirmed Panelist D. Christopher Chung, M.D., Vice President, Medical Affairs, R&D, and Engineering, Natus Medical Panelist Michael Leong M.D., Interim Executive Director, Pain Center Stanford Panelist Brian Wilfley, Chief Scientist and co-Founder, Triple Ring Technologies Presenting Entrepreneurs to be confirmed Topic Description Physicians are feeling the pressures of the changing policies, economies and technologies, which is influencing how they run their practices, and how they work with their patients. Our panel this month will feature physicians who are partnering with entrepreneurs, intrapreneurs and investors and proactively facing these changes, and a set of entrepreneurs who are developing solutions to support physicians in addressing these issues. Panelist Bios Facilitator from KPMG to be confirmed Panelist D. Christopher Chung, M.D., Vice President, Medical Affairs, R&D, and Engineering, Natus Medical D. Christopher Chung, M.D., has served as our Vice President R&D and Engineering since June 2003, and has served as our Vice President Medical Affairs since February 2003. Dr. Chung also served as our Medical Director from October 2000 to February 2003. From August 2000 to present, Dr. Chung has also served as a Pediatric Hospitalist at the California Pacific Medical Center in San Francisco. From June 1997 to June 2000, Dr. Chung trained as a pediatric resident at Boston Children's Hospital and Harvard Medical School. From May 1986 to July 1993, Dr. Chung worked as an Engineer at Nellcor, a medical device company. Dr. Chung holds a Bachelor of Arts degree in

19 3/28/2010

Computer Mathematics from the University of Pennsylvania and a Doctor of Medicine degree from the Medical College of Pennsylvania-Hahnemann University School of Medicine. He is board certified in Pediatrics and is a Fellow of the American Academy of Pediatrics. Panelist Michael Leong M.D., Interim Executive Director, Pain Center, Stanford University Michael Leong, MD is a Pain Medicine Specialist in Los Gatos, CA and Interim Executive Director of the Pain Center at Stanford University Pain Management Center. He was involved with clinical research in novel pain analgesics, particularly Prialt (intrathecal Ziconotide). Dr Leong has been a Medical Director in the Pharmaceutical industry, most recently at XenoPort, Inc. Michael holds a Doctor of Medicine from Georgetown University Medical School and completed his Anesthesiology residency and fellowship at Stanford University. He is board certified in Anesthesiology and Pain Medicine and is the author of about 30 publications. Dr Leong's main interests involve integrating academic teaching, clinical practice, and novel drug and device therapies for chronic pain. Panelist Brian Wilfley, Ph.D., Director, Chief Scientist, Triple Ring Technologies Dr. Brian Wilfley has over 20 years of experience leading development efforts for medical device and instrumentation companies. He has held senior scientific and engineering positions with Resonex, Inc., Park Scientific, Inc., Signature Bioscience, Inc., and NexRay, Inc. Combining a broad theoretical background with a highly developed experimental sense, Brian has experience across the full range of challenges encountered in developing complex measurement-based products. He is able to support the basic research and development of measurement-based equipment, as well as the detailed engineering required to implement it. His experience ranges from magnetism to x-rays, and includes a broad array of applications including biotech instrumentation, medical imaging, and optical inspection. Brian is a co-inventor of six issued patents and has authored a number of technical papers. He received his AB in Physics from the University of California at Berkeley and his Ph.D. in Physics from the University of California at San Diego. Presenting Entrepreneurs to be confirmed

***********************************************************************

Bio2Device Group, Tuesday Morning, April 20, 2010

Topic: tba Speaker: David DeNola Date and Time: Tuesday, April 20, 2010, 8:30 – 10:30 am Location: Sunnyvale City Council Chambers, 456 W. Olive, Sunnyvale, CA (across the street from Sunnyvale Public Library) Cost: Free Parking: On street and in NOVA and library parking lots across the street.

******************************************************************

Pharmaceutical Executive, Free Webinar, 8:00 am PT April 20, 2010

Topic: “The Future of Commercial Models in Pharma”

20 3/28/2010

Presenter: Chris Nickum, Vice President, Practice Leader, Commercial Effectiveness, IMS Health Patrick J. Retif, Global Leader, Commercial Effectiveness, Center of Excellence,IMS Health Moderator: William Looney, Editor-in-Chief, Pharmaceutical Executive Magazine Register for this FREE Webcast!

Date and Time: Tuesday, April 20, 2010, 8:00 am PT

Topic Description Today, many pharmaceutical executives are asking: How will we compete in a marketplace that, by 2015, will be 80% undifferentiated? What industry imperatives do we need to address in the design and implementation of our new commercial model? What does our organization need to do now in order to compete? Get the answers to these questions and more at the April 20 webcast, “The Future of Commercial Models in Pharma,” where you’ll hear IMS experts describe how your organization needs to align with the market and organize for the future in order to design, and implement, the most efficient and effective commercial model. Through our work with leading pharmaceutical companies around the globe, IMS has identified key imperatives that the industry must address in order to ensure a successful commercial model in the future. Whether you’re currently implementing a new commercial model or not sure where or how to get started, don’t miss this opportunity to learn more about how to best position your organization for success. Register today!

You’ll leave this webcast with:

A keen understanding of how your organization’s progress in implementing a new commercial model compares with your peers and how current trends are shaping the future Insight into which imperatives the industry must address now in order to establish successful commercial strategies Real-world examples of best practices, as well as tips on how to get your organization moving down the right path Who Should Attend: Leaders in commercial strategy, implementation and operations including account management, marketing, market research, sales operations, managed markets Register at https://event.on24.com/eventRegistration/EventLobbyServlet?target=registration.jsp&eventid=197402&sessionid=1&key=EF8CDD78C0A9008044EEB4A1B69AF17E&sourcepage=register For more information contact Jamie Carpenter - 440.915.7235

************************************************************

BioScience Forum, Wednesday Evening, April 21, 2010

Topic: TBA Speaker: Jean Deleage, Ph.D., Founding Partner and Managing Director, Alta Partners Date and Time: April 21st, 2010 Date and Time: Wednesday, April 21, 2010; 6:00pm - 9:00pm

21 3/28/2010

6:00 PM - networking 7:00 PM - dinner 8:00 PM - presentation Location: The Clarion Hotel, 401 East Millbrae Avenue, Millbrae Full info and Registration at: http://biosf.org/ Typical Cost: $50 before 11:55 PM, Monday, April 19th $60 on-site $35 full-time students pre-registration $45 full-time students on-site Acteva fees of $3 are added to the above prices Check website for latest information Cash or check accepted on the day of the event Parking is $2 Or you can pay with a check made out to "BioScience Forum" and sent to: BioScience Forum, 1442A Walnut Street, #308, Berkeley, CA 94709-1405 Please do not mail checks later than Thursday, April 15th If paying with check, do not complete registration with Cvent **********************************************************************

San Jose Biocenter, Thursday All-Day, April 22, 2010

Topic: “Meet with… Amgen”

Date and Time: Thursday, April 22, 2010 Agenda

9:00 AM - 9:30 AM Registration & Networking

9:30 AM - 10:30 AM Presentation & Q&A 10:40 AM - 11:30 AM

BioCenter Tour

11:30 AM - 12:30 PM

Lunch & Networking

12:30 PM - 5:00 PM One-on-one Meetings One-on-one Meeting Application & Costs • Application fee: FREE • Registration for one company representative: o $175 Regular o $150 Partners’ Network • Registration for two company representatives: o $250 Regular o $215 Partners’ Network • Registration for three company representatives: o $300 Regular o $255 Partners’ Network • Registration for four company representatives and above: o add $40 [or $30 for Partners’ Network] per attendee • BioCenter Residents and Affiliates: Free (Bio2Device Group members eligible for partner network discount; just note B2DG under affiliation) Presentation & Q&A Costs**

22 3/28/2010

• Regular Price: $40 • Partners' Network: $30 • BioCenter Members: Free (please RSVP to Aurélie) **Includes: Presentation & Q&A session ONLY. Seating is limited for this event, so early pre-registration is recommended to avoid disappointment! Additionally, there will be no on-site registrations. Topic Description Emerging companies find it increasingly difficult to reach the right person when seeking funding and/or partners. Through the “Meet with…” Series, we provide emerging companies with greater access to partnering and/or financing opportunities. In this session, Directors from Amgen will talk to potential licensees to first explain what they are looking for in a company. After the presentation, each pre-approved attendee* will be granted a private meeting with a Director from Amgen. *Registrations to one-on-one meetings are subject to approval of application. To apply, please send your Executive Summary by April 4, 2010 to Aurélie at aurelie@sjbiocenter.com. The Review Board, composed of the BioCenter management team, sponsors, partners and mentors, will then meet to consider your application. You will be notified on April 8, 2010 if your application is accepted or rejected. Registration must be completed upon approval to secure your meeting slot. ***************************************************************

VC Task Force, Thursday Evening, April 22, 2010 Event: “The Life Sciences VC Connection” Distinguished panelists: Scott Karchmer, Partner, Morgan, Lewis & Bockius, LLP KT Moorgat, Mohr Davidow Ventures Jonathan MacQuitty, Abingworth Sarah Bodary, SV Life Sciences Doug Foster Longitude Capital Date and Time:April 22, 2010 | 6:00-8:30 PM Doors open and networking: 6 PM Program: 6:30-8:30 PM Hors d'oeuvres and beverages will be served. Location: Two Palo Alto Square | Palo Alto Registration: $55 VC Taskforce Members, $65 Affiliate Organization Member, $75 General Seating is limited; register early! (Onsite registration is an additional $10.00 if space permits.) Event Sponsor: Morgan, Lewis & Bockius, LLP Topic Description The Life Science VC Connection programs through VC Taskforce offer an opportunity for entrepreneurs seeking start up funding to pitch in front of a distinguished panel of investors. VC Taskforce and Morgan, Lewis & Bockius, LLP have partnered to bring to you a scintillating program series to bring entrepreneurs and VCs together in the life science fields. The evening will be exciting and a terrific learning experience for all entrepreneurs. Entrepreneurs learn what VCs are looking for in a pitch presentation.

23 3/28/2010

Entrepreneurs seeking capital will pitch for 2 minutes in front of the VC panel. This is followed by 5 minutes of Q&A and then a non-rebuttal feedback by the panel. A score of (1-5) is given to each presenting company by each panel member. Please note that pitching time limits will be strictly enforced! Investors come and listen to entrepreneurs’ pitches. You never know where you’ll find your next deal. Find out how our panel of investors rate entrepreneurs’ pitches; which VCs pass and for what reasons; and which entrepreneurs other VCs want to talk to ASAP. Please let us know if you would like to participate on one of our Life Science VC Connection panels. This is a great opportunity for entrepreneurs to network with investors, present their company, and hear first-hand what it takes to raise early-stage capital in 2010. If you are an entrepreneur in a startup that is currently seeking capital, and would like to present your best 2 minutes elevator pitch to a panel of VCs, you must register in advance and have confirmation from the program manager that you are on the list of presenters. The maximum number of presenters is limited to ten. For more information contact Ashish Mahashabde, amahashabde@gmail.com, or 916-390-9233 Slots to present are assigned on a first-come basis. If a slot is available you must register and send Ashish Mahashabde your Cvent confirmation number and the name of your company. Receipt of your confirmation number ensures assignment of a presentation slot. You will also receive further instructions and advice on preparing your best pitch. Elevator Pitch Roundtable Chair: Meredith L. Warshaw, Ph.D., mlwarshaw@gmail.com This email address is being protected from spam bots, you need Javascript enabled to view it , 650-269-3156. Program Manager: Ashish Mahashabde, amahashabde@gmail.com This email address is being protected from spam bots, you need Javascript enabled to view it , 916-390-9233 *************************************************************** BayBio Institute NEST, Thursday Morning, April 29, 2010

Topic: Technology Showcase at SRI Date and Time: April 29th, 2010, 5:30-7:30pm Location: SRI International, 333 Ravenswood Avenue, Menlo Park CA 94025 Cost: Early Bird Registration through April 28th - $29; On-Site Registration, April 29th - $39 Register at http://www.acteva.com/booking.cfm?bevaid=196082 Topic Description BayBioNEST invites you to join us for the first of the 2010 Technology Showcases at SRI International. The NEST Tech Showcase allows the life sciences community to get a sneak peak at the science within often before it is published or patented and is also a great opportunity for the industry community to network with scientists, entrepreneurs and with each other. SRI International is an independent nonprofit research /development organization in existence over 60 years, whose discoveries, patents, and inventions have touched people's lives around the world! SRI's Biosciences Division provides complete discovery and preclinical development capabilities to take drugs and biologics from Idea to IND®. Our integrated program offers the scientific, technical, and regulatory expertise needed to expedite the process. We provide target identification, lead discovery/optimization, vaccine development,

24 3/28/2010

neuropharmacology research in sleep and pain, microbiology, efficacy models, comprehensive toxicology, PK/ADME, formulation, analytical chemistry, cGMP manufacturing, QA, IND preparation and government grant teaming services. In its CRO business, SRI has helped its clients, partners, and the Government advance well over 100 drugs into patient testing. SRI is also working to create the next generation of technologies in areas such as diagnostics, drug delivery, medical devices, and systems biology. *********************************************************************

RAPS, San Francisco Area Chapter, Friday, April 30, 2010

Topic: “Documenting Key Quality and Regulatory Processes” Speakers:

• Grace Bartoo, PhD, RAC, CQA, chief executive officer, Decus Biomedical, LLC • Paul Brooks, vice president healthcare solutions, BSI • Barry Craner, director of design assurance, Boston Scientific Corporation • Connie Hoy, vice president, regulatory affairs & quality assurance, XOFT, Inc. • Mark Perkins, consultant, Medical Device QA and RA Consulting

Date and Time: 30 April 2010, 7:45am–4:30pm

7:45am Registration Opens

7:45am–8:30am Registration Check-In, and Continental Breakfast

8:30am–11:45am Risk Management – Barry Craner Corrective and Preventive Actions (CAPA) – Mark Perkins

11:45am–12:45pm Luncheon and Networking

12:45pm–4:30pm Usability Engineering – Grace Bartoo Essential Requirements Matrices – Paul Brooks

Technical Files – Connie Hoy Panel Discussion and Q/A Period

Location: Crowne Plaza Mid-Peninsula, 1221 Chess Drive, Foster City, CA 94404

Registration:

RAPS and ASQ members: $175.00 Nonmembers: $200.00 Note: In order for ASQ Members to register at the member rate, it is necessary to submit your

registration using the registration form.

Register: http://www.raps.org/personifyebusiness/Bookstore/ProductDetail/tabid/55/Default.aspx?ProductId=6298 Topic Description Join your quality and regulatory colleagues from the ASQ Biomedical Discussion Group and the RAPS San Francisco Bay Area Chapter for a lively and informative one-day workshop on documenting key quality and regulatory processes. Experts use a mythical medical device to demonstrate by example how to prepare key documentation in the following areas:

• Risk Management • Corrective and Preventive Actions (CAPA) • Usability Engineering • Essential Requirements

25 3/28/2010

• Technical Files Quality, regulatory and other industry professionals currently working in these areas will leave the program with an expanded and practical understanding of document preparation. Note: In order for ASQ Members to register at the member rate, it is necessary to submit your registration using the registration form. Local Contacts: RAPS San Francisco Chapter Contact: Michelle Ragozzino, PhD, director of bioscience programs, UCSC Extension, +1 408 861 3861 American Society for Quaility Contact: Walter Crompton, +1 415 484 1688 ********************************************************************** Deloitte Recap Conference, Tuesday-Wednesday, May 25-26, 2010 Topic: Allicense 2010: Redefining the Threshold of Innovation Date and Time: Tue, May 25 to Wed, May 26 Location: Fairmont Hotel, San Francisco, CA, http://www.recap.com/88256AFE0004ABF3/allicense Cost: Standard Registration - Register on/after March 1, 2010-$1,950.00 "Team" Discount Registration: Register 2 or more from your company for 25% off each. (Price based on registration date) Registration fee includes 2 days of conference sessions, continental breakfasts and seated luncheons on both days, and attendance to the Breakthrough Alliance Awards Dinner on May 25, 2010. Conference Description The Allicense conference is a must-attend event for hundreds of biotech and Pharma executives The conference includes presentations and panel discussions on leading practices in business development and biotech finance, allowing executives to expand business connections and gain an in-depth perspective into current industry trends The two day agenda will include: • Keynote presentations from Bernard Munos (Lilly) and John Mendlein (Fate Therapeutics) • Panel sessions featuring buy-side and sell-side views of the marketplace • Networking opportunities to meet and interact with leading executives • The Allicense Award Dinner and presentation of the Breakthrough Alliance Award ***************************************************************** Bioscience Business Development: Building Value, Thursday and Friday, June 24-25, 2010 Intensive Course: Bioscience Business Development: Building Value, Thursday and Friday, June 24-25, 2010 (2 days of classroom and 2 months to complete project guided by instructor) Instructors: Audrey S. Erbes, Ph.D., Principal, Erbes & Associates and www.audreysnetwork.comand and Gilbert R. Mintz, Ph.D., President of GRM Associates Expert Guest Speakers: Harold (Hal) Etterman, MBA, Business Strategist Carolyn Feamster, MBA, VP, Business Strategy & Analysis

26 3/28/2010

Ginger R. Dreger, M.S., J.D., Partner, Arnold & Porter LLP Tom Gutshall, Chairman & Co-Founder of Cepheid Michael G. McCully, M.S., Director, Recombinant Capital

Please see www.ucsc-extension.edu/biobizdev for details Date & Time: June 24-25, 2010, Thursday and Friday, 8:30am-5pm Location: UCSC Extension in Silicon Valley, 2505 Augustine Drive, Santa Clara, CA 95053 Fee: $795; $715.50 through June 10 Topic Description UCSC Extension in Silicon Valley presents a two-day intensive course that brings the breadth of the Bay Area’s biobusiness development expertise to our Cupertino classroom. Whether financing start-up activities, trying to keep pace with the current burn rate, or moving a product into the marketplace, bioscience companies, both large and small, have a critical need for business development at every stage of their evolution. Learn the key roles that business development and licensing play in the commercialization of a new product and the development of a successful bioscience company. Santa Clara, CA. For more information, see www.ucsc-extension.edu/biobizdev Instructor Bios Audrey Erbes, Ph.D., Principal, Erbes & Associates and www.audreysnetwork.com has more than 30 years of marketing experience in the biotech and pharmaceutical industries, of which 25 years was in corporate management at Kowa Research Institute and Syntex Corporation. Gilbert R. Mintz, Ph.D., President of GRM Associates, a biotechnology consulting firm with expertise in business development, licensing and strategic planning.