ATLAS PENUNTUN PRAKTIKUM PATOLOGI ANATOMIProf.Dr.Syarifuddin Wahid, SpPADr. Upik A. Miskad, PhD, SpPA

Esophageal cancer. A, Adenocarcinoma usually occurs distally and, as in this case, often involves the gastric cardia. B, Squamous cell carcinoma is most frequently found in the mid-esophagus, where it commonly causes strictures.Downloaded from: StudentConsult (on 6 February 2010 03:24 PM) 2005 Elsevier

Esophageal cancer. A, Esophageal adenocarcinoma organized into back-to-back glands.

B, Squamous cell carcinoma composed of nests of malignant cells that partially recapitulate the organization of squamous epithelium.

Acute gastric perforation in a patient presenting with free air under the diaphragm. A, Mucosal defect with clean edges. B, The necrotic ulcer base is composed of granulation tissue.

ULKUS GASTER (VENTRIKULI). Tampak mukosa lambung yang masih intak (panah hitam) menjadi erosi (panah biru) sehingga kelenjar menghilang

ULKUS GASTER (VENTRIKULI). Dasar ulkus mengandung infiltrat limfosit (panah hitam), lekosit PMN (panah biru) dan makrofag (panah kuning)

Colorectal carcinoma. A, Circumferential, ulcerated rectal cancer. Note the anal mucosa at the bottom of the image. B, Cancer of the sigmoid colon that has invaded through the muscularis propria and is present within subserosal adipose tissue (left). Areas of chalky necrosis are present within the colon wall (arrow).

ADENOKARSINOMA KOLONTampak kelenjar colon yang normal (lingkaran hitam) yang dilapisi epitel selapis silindris dengan inti masih dibasal, . Lingkaran kuning menunjukkan daerah karsinoma dimana terjadi proliferasi epitel kelenjar yang atipia. Struktur kelenjar mengalami berdiferensiasi.

ADENOKARSINOMA KOLON. Kelenjar colon dilapisi sel-sel atipik, pleomorfik, anisositosis. Inti sel berkromatin kasar, membran inti irreguler, nukleoli prominent (panah hijau).

APENDISITIS KRONIK EKSASERBASI AKUT. Tampak mukosa apendiks yang atrofi (lingkaran kuning), proliferasi folikel limfoid (lingkaran hitam) dan hialinisasi pada sub-mukosa (panah hijau)

APENDISITIS KRONIK EKSASERBASI AKUT. Infiltrat sel radang terdiri dari sel-sel limfosit (panah kuning) dan sel lekosit PMN (panah hijau)

Figure 18-47 Hepatocellular carcinoma. A, Liver removed at autopsy showing a unifocal, massive neoplasm replacing most of the right hepatic lobe in a noncirrhotic liver; a satellite tumor nodule is directly adjacent. B, Microscopic view of a well-differentiated lesion; tumor cells are arranged in nests, sometimes with a central lumen.Downloaded from: StudentConsult (on 6 February 2010 03:42 PM) 2005 Elsevier

Figure 18-47 Hepatocellular carcinoma. A, Liver removed at autopsy showing a unifocal, massive neoplasm replacing most of the right hepatic lobe in a noncirrhotic liver; a satellite tumor nodule is directly adjacent. B, Microscopic view of a well-differentiated lesion; tumor cells are arranged in nests, sometimes with a central lumen.Downloaded from: StudentConsult (on 6 February 2010 03:42 PM) 2005 Elsevier

KARSINOMA HEPATOSELULARE. Tampak sarang-sarang proliferasi sel hepar dengan pola sinusoidal dan trabekular (lingkaran biru) yang dikelilingi daerah fibrosis (lingkaran hitam)

KARSINOMA HEPATOSELULARE .Sel-sel hepar tampak sangat pleomorfik, dengan inti anisonukleosis, membran inti irreguler, kromatin kasar, dan nukleoli prominent (panah biru)

Cirrhosis resulting from chronic viral hepatitis. Note the broad scar and coarse nodular surface.Downloaded from: StudentConsult (on 6 February 2010 03:36 PM) 2005 Elsevier

HEPATITIS KRONIK AKTIF. Tampak sel-sel hepar (hepatosit) dengan struktur yang masih baik (lingkaran biru) yang dikelilingi infiltrat sel radang limfosit dan lekosit PMN (ingkaran hitam)cc

HEPATITIS KRONIK AKTIF. Infiltrat sel radang terdiri dari limfosit dan lekosit PMN (panah hitam)

TBC USUS. Tampak massa nekrosis kaseosa (lingkaran biru) yang dikelilingi granuloma epiteloid (lingkaran kuning) dan infiltrat limfosit

TBC USUS. Granuloma epiteloid terdiri dari sel-sel limfosit (panah hitam), makrofag (panah kuning, sel datia Langhans (panah biru) dan sel epiteloid (panah merah)

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