‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex...

7
‐ The largest exclusively cave animal ‐ Top predator ‐ indicator of stable food chains and water quality ‐ Symbol of natural heritage and underground biodiversity ‐ Endangered by pollution and loss of habitat ‐ Endemic to Dinaric Karst Proteus anguinus

Transcript of ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex...

Page 1: ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex ratio and demographic structure of natural populations POTENTIAL OUTCOMES OF “PGP”

‐ The largest exclusively cave animal‐ Top predator ‐ indicator of stable food chains and water quality‐ Symbol of natural heritage and underground biodiversity‐ Endangered by pollution and loss of habitat‐ Endemic to Dinaric Karst

Proteus anguinus

Page 2: ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex ratio and demographic structure of natural populations POTENTIAL OUTCOMES OF “PGP”

1 ‐ SEX DETERMINATION

Sex ratio and demographic structure of natural populations

POTENTIAL OUTCOMES OF “PGP” IN A VIEW OF PROTEUS CONSERVATION

Establishment of sustainable breeding program

PGP ‐ genetic markers for sex determination

Page 3: ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex ratio and demographic structure of natural populations POTENTIAL OUTCOMES OF “PGP”

2 ‐ HOW MANY POPULATIONS/SPECIES OF PROTEUS ARE THERE?

3 ‐ HOW LARGE AND HOW STABLE ARE THESE POPULATIONS?

OPTIMISATION OF CONSERVATION STRATEGIES

PGP ‐ estimation of genetic diversity of populations and trends of their dynamics 

PGP ‐ genetic markers that would allow distinguishing between populations

Page 4: ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex ratio and demographic structure of natural populations POTENTIAL OUTCOMES OF “PGP”

EXTREME STARVATION AND FEEDING

PGP ‐ potential to improve our understanding of mechanisms behind starvation, metabolic abnormalities and other 

adaptations to cave environment, as well as their relevance for human health

‐ Starvation without an anorexia‐ Overeating without becoming obese

… tend to be features of cave organisms

OTHER POTENTIAL OUTCOMES OF “PGP”

Astyanax mexicanus

Page 5: ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex ratio and demographic structure of natural populations POTENTIAL OUTCOMES OF “PGP”

REGENERATION

PGP ‐ may ease the search of mechanisms behind regeneration ‐with a prospect of development of novel biomedical approaches 

‐ full regeneration of damaged or missing organs is a common feature of salamanders

Ambystoma mexicanum

Pleurodeles waltl

Page 6: ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex ratio and demographic structure of natural populations POTENTIAL OUTCOMES OF “PGP”

LONGEVITY

‐ the longest lifespan among amphibians

PGP ‐ potential to illuminate the mechanisms behind longevity through genetic differences 

between Proteus and other amphibians

‐ one of the largest genomesGENOME SIZE

PGP ‐ knowing the structure of genome may contribute to understanding the purpose and origin 

of non‐coding segments of genomes

Necturus maculatus Lepidosiren paradoxa

Page 7: ‐The largest exclusively cave animal ... - Proteus genome€¦ · 1 ‐SEX DETERMINATION Sex ratio and demographic structure of natural populations POTENTIAL OUTCOMES OF “PGP”

https://www.proteusgenome.com/