Asmerom Lebasi, Quinn Quaderer, Tamrat Oda. Classification/ Taxonomy Domain: Eukaryota Kingdom:...
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Transcript of Asmerom Lebasi, Quinn Quaderer, Tamrat Oda. Classification/ Taxonomy Domain: Eukaryota Kingdom:...
Paragonimus westermani/kellicati
Asmerom Lebasi, Quinn Quaderer, Tamrat Oda
Classification/ Taxonomy Domain: EukaryotaKingdom: AnimaliaPhylum:Platyhelminthes
Class: TrematodaSubclass: DigeneaFamily: Paragonimidae
Genus: Parnagonimus
Species: westermani
Morphology
adult fluke has reddish-brown in color, oval in shape
looks like coffee bean
10 mm long X 5 mm wide
Geographic Distribution:• Paragonimus
westermani is distributed in southeast Asia and Japan.
Paragonimus kellicotti is endemic to Eastern U.S. and Canada:
-rarely results in human infection
HostsDefinitive Host:• Humans (rare for P.
kellicotti )
• Cats• Dogs • Pigs
Intermediate Host: 1. Snails 2. Crabs and crayfish
.
My name is BoI am a definitive host
http://www.ochealthinfo.com/epi/imf
I ’m sooo wasted!!
LIFECYCLE
Life Cycle of Paragonimus Westermani/Kellicotti1. Eggs are excreted unembryonated in the spit, or are swallowed and passed in the feces.
2. In the external environment, the eggs become embryonated.
3. Miracidia hatch and seek the first immediate host(snail) and penetrate its soft tissues.
4. Miracidia go thru 3 life stages while in the snail: a. Sporocysts b. Rediae that give rise to many cercariae. c. Cercariae emerge from the snail.
5. Cercariae invade the second intermediate host, the crab or crayfish, where they encyst and become metacercariae. Infective stage.
6. Humans consume undercooked or pickled crab or crayfish that have P. westermani/kellicotti.
7. Metacercariae excyst in the duodenem.
8. Penetrate thru the intestinal wall into the peritoneal cavity, then thru the abdominal wall and diaphragm into the lungs.
9. Encapsulate in the lungs and develop into adults.
10. Adults in the lungs lay eggs which are then excreted in spit or feces.
SymptomAcute phase Chronic phase
diarrhea, Chest pain,abdominal pain, Fever cough, skin rash notable for
pale red, raised, itchy bumps
During the, pulmonary manifestations
coughdiscolored sputum hemoptysis chest radiographic
abnormalities. chronic cough
Diagnosis Microscopic detection of eggs in feces or
sputumImmunioblot for IgG antibody detectionRadiological method can be used tooX-ray the chest cavity and look for worms a lung biopsy
TreatmentPraziquantel (95% efficiency)
Prevention
• In order to prevent infection
do not eat uncooked crab marinated in line juice because the lime do not kill the parasite
Public Health Concerns
More than 22 million humans have it