ASAS criteria for an axial SpA diagnosis · 2019-11-06 · Modified NY (mNY) criteria for an AS...
Transcript of ASAS criteria for an axial SpA diagnosis · 2019-11-06 · Modified NY (mNY) criteria for an AS...
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* Acute inflammation (on MRI) highly suggestive of sacroiliitis or definite radiographic sacroiliitis.
†SpA features:
• Inflammatory back pain
• Arthritis
• Enthesitis (heel)
• Uveitis
• Dactylitis
• Psoriasis
• Crohn’s disease/UC
• Good response to NSAIDs
• Family history of SpA
• HLA-B27
• Elevated CRP (with chronic back pain)
Sacroiliitis on imaging*
+≥1 SpA feature†
or
ASAS=Assessment of SpondyloArthritis international Society; CRP=C-reactive protein; HLA=human leukocyte antigen; MRI=magnetic resonance imaging; NSAIDs=nonsteroidal anti-inflammatory drugs; SpA=spondyloarthritis; UC=ulcerative colitis.
Radiographic evidence or lab indices, plus clinical signs/symptoms1
In patients with back pain ≥3 months and age at onset <45 years:
ASAS criteria for an axial SpA diagnosis
HLA-B27 positive
+≥2 other SpA features†
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Modified NY (mNY) criteria for an AS diagnosis
References: 1. Rudwaleit M, van der Heijde D, Landewé R, et al. The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis. 2009;68(6):777-783. 2. van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum. 1984;27(4):361-368.
Radiographic evidence of sacroiliitis required2
AS=ankylosing spondylitis.
Low back pain for at least 3 months (improved by exercise, not relieved by rest)
orLimitation of motion of the lumbar spine
orChest expansion
decreased relative to normal values for age/sex
Bilateral sacroiliitis grade ≥2
+Unilateral sacroiliitis
grade 3 to 4
and
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