Artificial Hearts

Ashraf W Khir October 2010

Outline

• Introduction

• Problem and it source

• The need

• Challenges in meeting the need

• The available solutions

• Potential solutions

Artificial Hearts

• What are they?

Artificial Hearts

• What are they?

• What are they used for?

Artificial Hearts

• What are they?

• What are they used for?

• Who needs them?

Artificial Hearts

• What are they?

• What are they used for?

• Who needs them?

• Big industry?

Size of the Problem

• In the UK only– 350,000 new cases diagnosed with heart failure

• Global “epidemic” problem– 1 in every 5 of us will die of cardiovascular disease

• Industry– Billion $$ and expanding

Source of the Problem

• Diet– Fast food– lack of a balanced diet

• Socio-economical patterns– Obesity

• Lack of body exercise– cars vs. cycling– TV remote

• Heart disease – coronary artery disease (CAD)– Ventricular disease

Challenges

• Size

Challenges

• Size

• Weight

Challenges

• Size

• Weight

• Material

Challenges

• Size

• Weight

• Material

• Power

Challenges

• Size

• Weight

• Material

• Power

• Price

Challenges

• Size

• Weight

• Material

• Power

• Price

• Residence time

Challenges

• Size

• Weight

• Material

• Power

• Price

• Residence time

• Sheer stresses – hemolysis

Challenges

• Size• Weight• Material• Power• Price• Residence time• Sheer stresses – hemolysis• Blood path - thrombosis

Challenges

• Size• Weight• Material• Power• Price• Residence time• Sheer stresses – hemolysis• Blood path – thrombosis• Price

Challenges

• Size• Weight• Material• Power• Price• Residence time• Sheer stresses – hemolysis• Blood path – thrombosis• Price

Available Solutions

• LVAD– Axial flow pumps– Centrifugal pumps– Pusher plate pumps

• RVAD– Axial flow pumps– Centrifugal pumps– Pusher plate pumps

• BiVAD– BiVad

• TAH– BiVAD

Future Solutions

• New Technologies

• Improvement– Smaller– Lighter– Consumes less power– More efficient– Less blood damage