Application of Artificial Skin by Animal Cell Culture

8/16/2019 Application of Artificial Skin by Animal Cell Culture

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APPLICATION OF ARTIFICIAL SKIN

by ANIMAL CELL CULTURE


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1) Alternatives to Animal Testin

• Animal Testin ! met"o# to $arry o%tvario%s tests on animals to ens%ret"e sa&ety o& t"e 'ro#%$t &or %sae(

• In $osmeti$ testin animalse'erien$e #is$om&ort* s%+erin an#%ltimately #ie(


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Test &or animal testin are ,

• S-in $orrosion

• S-in irritation

•

S-in absor'tion• P"oto!toi$ity

• Pyroene$ity


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• Non animal testin is t"e met"o# ."i$"ma-e %se o& vario%s #i+erent alternativesrat"er t"an e'erimentin on animals(

• /el's in avoi#in "arm to animals(

• It is more reliable an# a$$%rate(

• It is $ost e+e$tive(

• Pain&%l an# #ea#ly tests on animals $an

be avoi#e#(

• HUMAN TISSUE CULTURE


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0) Treatment o& %rns 23o%n#

/ealin

• treatment o& 'eo'le s%+erin severe b%rns(

• "ealin o& .o%n#s 'ro#%$e# on s-in by

vario%s #isease# $on#itions(

• $"roni$ s-in %l$ers,

! s-in %l$ers #evelo'e# as a res%lt o& #iabetes


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/o. it .or-s44

• C%lt%re# s-in is se$%re# over .o%n#(

• T"e s-in remains in 'la$e &or several.ee-s an# allo.s ne. tiss%e to ro.into bottom matri layer(

• To' layer 'rovi#es

'rote$tion &rom in&e$tion

an# #e"y#ration(


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5) Provi#in mo#el environment &or

resear$"

• Pro#%$e# vario%s s-in relate# resear$"(

• 6isease# s-in $on#ition $an be in#%$e#%n#er in vitro

$on#itions in s%$" livins-in(

• T"ey $an be st%#ie# $losely into#evelo'in 'robable $%re(


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•S-in $an$er!Melanoma

•s-in $%lt%re# are very $onvenient &or mo#elint"e ro.t" an# 'roression o& melanoma $ells(

•observin t"e &ormation o& 'imente# lesions o&in sit% melanoma in $%lt%re# s-in(

•s-in mo#els "ave also serve &or eneti$ an#

&%n$tional analyses o& early staes o&melano$ytes #evelo'ment(

Application of Artificial Skin by Animal Cell Culture

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