“Nature and Science Working Together ”

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A REMARKABLE DISCOVERY

THE ENDOCANNABINOID SYSTEM AND YOUR HEALTH

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In 1988 researchers and scientists in the U.S. and Israel, discovered an unknown molecular

signaling system and intricate network of receptors found on almost every organ in the

human body. It is uniquely responsible for regulating a broad range of biological functions.

It was named the Endocannabinoid System (ECS).

The ECS is the body’s primary regulatory system that maintains the intricate balances and

cellular signaling required for the healthy functioning of the neurological, cardiovascular,

respiratory, immune, gastrointestinal and musculoskeletal systems. The ECS controls

many important cellular and metabolic processes and keeps a wide range of body

functions in equilibrium throughout your nervous system, immune system, digestive

system, endocrine glands, brain, heart, lungs, kidneys, liver, spleen, bones, and lymph cells.

It is now generally regarded as one of the most important physiological process formaintaining health and well-being. The ECS regulates key aspects of your physical,emotional, and mental health, including

• Digestion & Appetite• Emotions & Mood• Pain• Memory• Inflammation• Motor control

• Immune function• Motivation, pleasure and reward • Metabolism• Sleep• Stress response• Temperature regulation

THE ENDOCANNABINOID SYSTEM AND YOUR HEALTH

In the human body, the ECS is believed to have

more cellular receptor sites than any other system

including the nervous system. There are two

different receptor sites, named CB1 and CB2.

These receptors send information to cells, organs,

and the nervous system. The relaying of this

cellular information is critical to maintaining

optimal health and well-being (homeostasis).

When an imbalance is detected within our physiological processes , the body synthesizesendocannabinoids that interact with these receptors. This stimulates a chemical responsethat works to return the physiological process back to homeostasis and equilibrium.

However in many cases there is a deficiency in ECS signaling. This condition is known as

Clinical Endocannabinoid Deficiency (CED). This condition occurs when our body does not

produce enough endocannabinoids, enzymes have damaged the endocannabinoids, or an

outside source such as foods, medications or pollutants have decreased ECS signaling. A

growing body of evidence unequivocally demonstrates that deficiency of endocannabinoid

signaling is linked to many debilitating ailments such as chronic pain, inflammation,

fibromyalgia, irritable bowel syndrome, chronic fatigue , migraine and more.

CED is also associated with an inability to adapt to anxiety, chronic stress, post-traumaticstress disorder and can result in depressive behavioral responses. Phyto-cannabinoids areconsidered an effective treatment to supplement this deficiency. By stimulating andsupporting the endocannabinoid system you can regain relief from a multitude of illnessesand conditions. *

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THE ENDOCANNABINOID SYSTEM AND YOUR HEALTH

Using Cannabinoids to Improve Your Health

The Endocannabinoid System or ECS, is presently known to include

• Receptor sites, small cellular docking stations, called CB1 and CB2

• Compounds known as endocannabinoids that bind to these receptor sites torelay cellular information to organs and the nervous system.

Research has shown immense potential for phyto-cannabinoids to help improve thefunctioning of many systems in the human body. Some of the common ailments that haveseen improvement from cannabinoid supplementation include:

▪ Chronic Pain▪ Inflammation▪ Stress & Anxiety▪ Gastrointestinal issues▪ Depression▪ Sleep disorders

➢ The endocannabinoid system protects the GI tract from inflammation and abnormallyhigh gastric and enteric secretion. Studies have shown stimulation of theendocannabinoid system can provide benefit and new remedies for gastrointestinalailments including nausea, gastric ulcers, gastrointestinal reflux disease, paralytic ileus,inflammatory bowel disease, and hyperactive bladder. *

➢ Cannabinoids are strong neuroprotective antioxidants and provide protection to your brain and nervous system. As a potent regulator and balancer, they can protect against chronic stress and mood disorders as anxiety and depressive behavior *

➢ Cannabinoids can help ameliorate mood by their effect on serotonin receptors. *

➢ Studies indicate that endocannabinoids may provide benefit to help normalize sleeppatterns, particularly to promote rapid-eye-movement or REM sleep. More research isrequired to substantiate sleep improvement, which would improve moods associatedwith poor sleep patterns. *

➢ Clinical data indicates that Phyto-cannabinoids administered together are moreeffective at ameliorating neuropathic pain and inflammation. *

There are over 100 different identified cannabinoids, and most of them interact with eachother to provide a potent synergy. This is called the “entourage effect” and is one of thebiggest advantages of using a full spectrum phyto-cannabinoid extract. A singlecannabinoid, such as CBD, that is chemically isolated or synthesized in a lab simply doesnot offer the complete spectrum of health benefits that a full plant extract provides.

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THE ENDOCANNABINOID SYSTEM AND YOUR HEALTH

In Nature the highest concentration of cannabinoids are in the Industrial Hemp plant;with over 80 identified cannabinoids including CBD, CBN, CBG, CBC, 13 active Terpenesand over 400 other compounds. Cannabinoids and Terpenes work extremely welltogether to produce a significant synergy that enhance each other.

Terpenes are quite potent and provide very effective therapeutic benefits. For example,β-Caryophyllene is found in high concentrations in spices and plants such as blackpepper, Hops, and rosemary. β-Caryophyllene, also known as the first dietarycannabinoid, has a strong affinity and binds to CB2 receptors providing potent pain andanti-inflammatory activity. This explains why black pepper (β-Caryophyllene) commonlyappears in many anti-inflammatory preparations.

➢ Cannabinoids and Terpenes work effectively together in the treatment of neuropathicand chronic pain, inflammation and multiple GI tract and digestive disorders. Studiesindicate that the pronounced neuropathic pain relief and anti-inflammatory effects ofβ-Caryophyllene + Humulene are comparable to those observed in dexamethasone-treated animal trials *

➢ The combination of cannabinoids and β-Caryophyllene may be an effective anti-arthritic and holds promise in rheumatoid arthritis research. *

Industrial Hemp has been used and cultivated by mankind for at least 6000 years. Hempfiber has been used extensively throughout history for items ranging from rope tofabrics to industrial materials. Hemp seeds are an excellent source of plant-basedprotein, with high levels of omega 3 and omega 6 oils, and rich in vitamins and minerals.However the seeds do not contain any of the Phyto-cannabinoids or terpenes. These areonly found in the stalks and flowers of the plant.

Industrial Hemp has been the subject of intensive medical research and studiesworldwide. Over the past 30 years, research in Europe on cannabinoids and the medicalapplications of Industrial Hemp have initiated the vast scientific and medical interestwitnessed today.

The passage of the The Hemp Farming Act of 2018, part of The 2018 Farm Bill legislationsigned into law in December 2018, changed the status of industrial hemp in the U.S. froma controlled substance to an agricultural commodity. The Hemp Farming Act opens thedoor for domestic production and will increasingly encourage and expand U.S.institutional clinical research. The Act accordingly also now provides Americanconsumers the opportunity to access and experience the health benefits available fromPhyto-cannabinoids through the healing and restorative actions they bring to theEndocannabinoid system.

* These Statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose,treat, cure, or prevent disease.

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THE ENDO

At Golden Oasis we share a simple Mission:

“Bringing Nature and Science Together

We wanted to make sure that people have access to a safe, reliable and highly effective

Hemp oil supplement that they can count on for their health-related needs. The proprietary

formulas we create are based on science, research and great advice from Pharmacologists,

clinical Researchers and bio-Nutritionists. Each ingredient is proven to be of tremendous

benefit individually and also adds a greater synergistic value to the whole to maximize the

therapeutic actions.

Golden Oasis Plus+ uses only a full plant extract obtained via a Supercritical CO2 extraction

process. This method ensures that all beneficial Cannabinoids and Terpenes profiles are

maintained without using any chemicals or additives. The small levels of THC naturally

present in Hemp are isolated and completely removed during the extraction process.

Golden Oasis Plus+ is 100% THC-free.

Golden Oasis Plus+ contains only the purest ingredients that meet a rigorous selection

process. We source all our ingredients in-house, domestically and from Europe, to find

supreme quality, organic, lab-tested products. We take great pride in producing the highest

therapeutic grade best-in-class products… and are equally proud to share them.

Providing your body with the elements it requires to maintain and restore internal bio-system balances is a necessity for good health and well-being. Keeping the ECS systemfunctioning optimally is now generally regarded as one of the most important and highlyeffective action you can take for maintaining health and well-being.

Today, millions of people are finding the relief they need and discovering the powerfulactions of cannabinoids and their unique properties to restore and maintain the healthyfunctioning of your vital endocannabinoid bio-system.

Visit us online at www.GoldenOasisLLC.com to find out more on this remarkable productnow with free shipping.

To Your Good Health !

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THE ENDOCANNABINOID SYSTEM AND YOUR HEALTH

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THE ENDOCANNABINOID SYSTEM AND YOUR HEALTH

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