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Transcript of ANYGEN - prokcssmedia.blob.core.windows.net€¦ · the peptide synthesis. Custom Peptide Catalog...
2 3ANYGEN
TotalBiomolecules
ServiceSystem
Key TechnologySynthesis & Purification
Custom PeptideConfidentiality
Peptide for Industrial UseCosmetic & Food Ingredients
Catalog PeptideStrong R&D Support
CMO ServicePreclinical
Peptide APIsGeneric
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ANYGEN Synthesizing Therapeutic Future
We manufacture high-quality custom-made peptides by applying our thorough product managing system (ISO 9001, 14001, GMP Certificated) in the synthesis and purification of peptides, and we supply the peptides de-manded by customers by applying custom-made synthesis and purifications according to the level of difficulty in the synthesis and types of modification.
Key TechnologyANYGEN supplies various types of high-quality peptides promptly by applying our optimal synthesis technology and extensive experiences in the peptide synthesis.
CustomPeptide
CatalogPeptide
CMOService
Peptide Service- ISO 9001, 14001- GMP
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Custom Peptide Synthesis Service
Modification
Order
MASS, HPLC
Final Product
Synthesis(Fmoc-Chemistry)
Purification(RP- HPLC)
Quality Control(Maldi-Tof MASS, HPLC)
ANYGEN’s Total Quality Control System
MASS, HPLC
Acetylation / Biotinylation
Fluorescence Dye (FITC/Cy3/Cy5 and its derivative)
DNP(2,4-D-Niroanilide)
Dabcyl/Dabsyl/Dancyl Phosphorylation (Ser, Thr, Tyr)
Fatty Acid Disulfide Bonds
PEG Cyclization EDANS
MAP(Multiple / Antigen peptide)
AMC (Aminomethylcoumarin)
pNA(p–Niroanilide)
Esterification
Amidation
KLH/BSA Conjugation to Antibody Production
N-terminal Side Chain C-terminal
■ We offer peptide synthesis with faithful value■ >80%, >95%, >98% purity grade■ mg ~ kg scale■ Academic, pharmaceutical and industrial use
4 5ANYGEN
ANYGEN Synthesizing Therapeutic Future
Catalog Peptide Service
Cosmetic PeptideName Function in cosmetic products
Acetyl Hexapeptide Relaxes facial wrinkles, reducing the degree of existing wrinkles.
Palmitoyl Hexapeptide Wrinkle prevention, wrinkle repair and eye contour care.
Palmitoyl Tetrapeptide Anti-aging, wrinkle smoothing, and cutaneous barrier repair.
Palmitoyl Pentapeptide Anti-wrinkle and collagen production stimulation.
Copper Tripeptide Wound healing and revascularization of tissues.
Palmitoyl Tripeptide Anti-aging and anti-wrinkle effects and cutaneous restructuration and repair.
CatalogPeptide
PeptideHormone
β-Amyloid
PeptideNeurotoxin
NeuroPeptide
CellPermeable
Peptide
GPCRLigand
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GMP Service
■ Bulky-scale solid & solution phase synthesis■ Proportionately scaled HPLC purification■ Lyophilization■ Cleanrooms from class 100,000 to 10,000
■ QA/QC and regulatory support■ Expertise in all production and purification techniques■ Dedication to quality and GMP compliance
GMP Bulk peptide : from ~g to ~kg scale
■ Appearance■ Solubility■ Identity(Via mass spectral analysis)■ Related substances (HPLC)■ Assay (as mass balance)■ Counterion content counter-ion co■ Moisture content
■ Peptide content (by N%)■ TFA content■ Chloride content■ Residual organic solvents■ Bioburden■ Endotoxin■ Other API-specific parameters
Our standard GMP specifications include :
Generic Peptide APIsPeptide Name Application
Leuprorelin Prostate Cancer
Desmopressin Diabetes Incipidus
Ganirelix GnRH antagonist, IVF
Liraglutide Type2, Diabetes, Obesity
Lanreotide Acromegaly
Octreotide Acromegaly
6 7ANYGEN
ANYGEN Synthesizing Therapeutic Future
CMO Service
■ Characterization ■ Working Standard Preparations■ Analytical Methods Validation ■ Three Batches Validation■ Process Validation
Process Development & Validation
Looking for a partner to develop peptide drugs?
Clinical Phase I
---------------PROCESS
DEVELOPMENT
Clinical Phase II
--------------PROCESS
VALIDATION
Clinical Phase III
---------------REGISTRATION
ComericalGenerics-------------
MANUFACTURING
YourPeptide
Peptide API development process
■ ICH Stability Study ■ CTD/DMF Preparation■ Regulatory Support ■ Commercial Manufacturing
Registration & Manufacturing
www.anygen.com
Rm. 206, Pilot plant, Gwangju Technopark,333, Cheomdangwagi-ro, Buk-gu, Gwangju, 61008, Korea
ANYGEN CO., LTD.
Tel : +82-62-714-1166 / Fax : +82-62-714-1188 / Order mail : [email protected]