Antimicrobial Properties of Phenolic Compounds

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    Apigenin

    Luteolin

    Kaempferol

    QuercetinMyricetin

    Rutin

    Isoquercitrin

    Naringenin

    Hesperetin

    (+) Catechin

    (-) Epigallocatechin

    Pelargonidin

    CyanidinDelphinidin

    PeonidinMalvidin

    Kuromanin

    Flavones

    Flavonols

    Flavanones

    Flavanols (Catechins)

    Anthocyanidins

    R1 R2

    H

    OH

    H

    OHOH

    H

    OH

    H

    OH

    OH

    OH

    H

    OHOH

    OCH3OCH3OH

    H

    H

    H

    HOH

    OH

    H

    OH

    OCH3

    H

    OH

    H

    HOH

    HOCH3H

    Cinnamic acid

    3-Coumaric acidCaffeic acid

    Ferulic acid

    H

    HH

    H

    H

    OHOH

    OH

    H

    HOH

    OCH3

    R1

    R1 R2

    R1 R2

    R1 R2

    R1 R2

    R2 R3

    HO O

    OOH

    R1

    R2

    OH

    5

    7

    4

    23

    4'

    HO O

    OHO

    OH

    4

    23

    R3

    HO O

    OHO

    4

    23

    HO O

    HO

    4

    23

    OH

    OH

    HO O

    HO

    R3

    OH

    +

    COOH

    5'6'

    R1

    R2

    R1

    R2

    R1

    R2

    R1

    R2

    R1

    R2

    R3

    Chlorogenic acid

    HOOH

    OHO

    HO

    H

    HH

    O OH

    OH

    O

    A C

    B

    Phenolic acids

    H

    HH

    rutinose-D-glucose

    R3

    H

    HH

    HH

    glucose

    R3

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    107

    108

    109

    1010

    0 5 10 15 20 25 30

    Incubation time (h)

    cfuml1

    cfuml1

    cfuml1

    cfuml1

    cfuml1

    cfuml1

    107

    108

    109

    1010

    0 10 20 30 40

    Incubation time (h)

    106

    107

    108

    109

    0 5 10 15 20 25 30

    Incubation time (h)

    106

    107

    108

    109

    1010

    0 2 4 6 8 10

    Incubation time (h)

    106

    107

    108

    109

    1010

    0 5 10 15 20 25 30

    Incubation time (h)

    105

    106

    107

    108

    109

    0 5 10 15 20 25 30

    Incubation time (h)

    (a) (b)

    (c)

    (e) (f)

    (d)

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    104

    105

    106

    107

    108

    109

    0 2 4 6 8 10

    Incubation time (h)

    107

    108

    109

    1010

    0 5 10 15 20 25 30

    Incubation time (h)

    106

    107

    108

    109

    0 5 10 15 20 25 30

    Incubation time (h)

    cfuml

    1

    cfuml

    1

    cfuml

    1

    (g)

    (h)

    (i)

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