Animal Nutrition

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Animal Nutrition Example 1: Nutrition Homeostatic Mechanisms 1 (function)

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Homeostatic Mechanisms 1 (function). Animal Nutrition. Example 1: Nutrition. Big Questions:. How do the physiological systems of organisms help the organism maintain homeostasis? - PowerPoint PPT Presentation

Transcript of Animal Nutrition

Page 1: Animal Nutrition

Animal Nutrition

Example 1: Nutrition

Homeostatic Mechanisms 1 (function)

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Big Questions:How do the physiological systems of organisms help the organism maintain homeostasis?

How have the physiological systems of organisms been adapted to the constraints of the environments that organisms live in?

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What does an organism need to do?Stay alive (at least until reproduction)!

The physiological systems that an organism has are adapted to this purpose.

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Generalized Animal Body Plan:

How does each system contribute to homeostasis?

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Generalized PlantBody Plan

What do each of the following do to maintain homeostasis?• root

root tip/root hairs• shoot (stem)

Nodes/internodesBuds

Terminal/apical/axillary budsFlower buds & flowers

• leavesmesophyll tissue/veins (vascular bundles)

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How does the environment influence an organism’s physiology?

Tremendously!

Natural selection will tend to drive the adaptation of physiology to environmental contstraints.

This has resulted in a variety of mechanisms for maintaining homeostasis

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Animal Nutrition

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Nutritional requirements• Animals are heterotrophs

– need to take in food– Why? fulfills 3 needs…

• fuel = chemical energy for production of ATP • raw materials = carbon source for synthesis• essential nutrients = animals cannot make

– elements (N, P, K, Fe, Na, K, Ca...), NAD, FAD, etc.

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Kwashiorkor (a protein deficiency) in a Haitian boy

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How do animals get their food?

filter (suspension) feeding substrate feeding

fluid feeding bulk feeding

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Different diets; different lives• All animals eat other organisms

– Herbivores• eat mainly plants

– gorillas, cows, rabbits, snails

– Carnivores• eat other animals

– sharks, hawks, spiders, snakes– Omnivores

• eat animals & plants– cockroaches, bears, raccoons, humans– humans evolved as hunters, scavengers & gatherers

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Getting & Using Food• Ingest

– taking in food• Digest

– mechanical digestion• Breaking food into smaller pieces

– chemical digestion• breaking down food into small

molecules to be absorbed into cells• Absorb

– absorb across cell membrane• Diffusion, active transport

• Eliminate – undigested extracellular material

passes out of digestive system

intracellulardigestion

extracellulardigestion

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Digestive systems

Everybody’s got one!

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Human digestive systemAlimentary Canal

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Common processes & structures

• Movement & Control – peristalsis

• push food along by rhythmic waves of smooth muscle contraction in walls of digestive system

– sphincters• muscular ring-like valves, regulate the passage of

material between sections of digestive system• Accessory glands

– salivary glands, pancreas, liver & gall bladder• secrete digestive juices (enzymes & fluid)

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Swallowing (& not choking)

• Epiglottis – problem: breathe & swallow through same orifice– flap of cartilage closes trachea (windpipe) when swallowing– food travels down esophagus

• Esophagus – move food along to stomach by peristalsis

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Ingestion• Mouth

– mechanical digestion• Teeth: breaking up food

– chemical digestion• saliva

– Amylase: enzyme digests starch

– Mucin: slippery protein (mucus). Protects lining of digestive system, lubricates food.

– Buffers: neutralize acid to prevent tooth decay

– anti-bacterial chemicals: lysozyme.

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mouthbreak up foodmoisten food digest starchkill germs

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stomachkills germs store food break up fooddigest proteins

cardiacsphincter

pyloricsphincter

mouthbreak up foodmoisten food digest starchkill germs

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Stomach• Functions

– food storage: can stretch to fit ~2L food

– disinfect food• HCl = pH 2

–kills bacteria, breaks apart cells

– chemical digestion• Pepsin: enzyme breaks down

proteins–secreted as pepsinogen

»activated by HCl

But the stomach is made out of protein!What stops the stomach from digesting itself?mucus secreted by stomach cells protects stomach lining

Ooooooh!Zymogen!

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• Used to think ulcers were caused by stress

– tried to control with antacids

• Now know ulcers caused by bacterial infection of stomach

– Helicobacter pylori– now cure with

antibiotics

Ulcers

inflammation of stomach

inflammation of esophagus

Colonized by H. pylori

Free of H. pylori

white blood cells

cytokines

inflammatory proteins(CagA)

cell damaging proteins(VacA)

helper T cells

neutrophil cells

H. pylori

Coevolution of parasite & host

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Revolutionizing healthcare"for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease"

J. Robin Warren Barry Marshall

1982 | 2005

Helicobacter pylori

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stomachkills germs break up fooddigest proteinsstore food

pancreasproduces enzymes to digest proteins & starch

mouthbreak up foodmoisten food digest starchkill germs

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Small intestine• Function

– major organ of digestion & absorption – chemical digestion: digestive enzymes– absorption through lining: over 6 meters!

• small intestine has huge surface area = 300m2 (~size of tennis court)

• Structure– 3 sections

• duodenum = most digestion• jejunum = absorption of nutrients & water• ileum = absorption of nutrients & water

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Duodenum • 1st section of small intestines

– acid food from stomach mixes with digestive juices from accessory glands:

pancreas liver gall bladder

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Pancreas • Digestive enzymes

– peptidases• trypsin

– trypsinogen• chymotrypsin

– chimotrypsinogen• carboxypeptidase

– procarboxypeptidase– pancreatic amylase

• Buffers – reduces acidity

• alkaline solution rich in bicarbonate (HCO3-)

• buffers acidity of material from stomach

Explain how this is a molecular example of structure-function theme.

Ooooooh!Zymogen!

What stopspancreas

from digesting itself

small intestines

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Liver • Digestive System Functions

– produces bile• stored in gallbladder until needed• breaks up fats

– act like detergents to breakup fats

Circulatory System Connectionbile contains colors from old red blood cells collected in liver =iron in RBC rusts & makes feces brown

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pancreasproduces enzymes to digest proteins & starch

stomachkills germs break up fooddigest proteinsstore food

liverproduces bile

- stored in gall bladderbreak up fats

mouthbreak up foodmoisten food digest starchkill germs

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small intestinesbreakdown all foods

- proteins- starch- fats- nucleic acids

absorb nutrients

stomachkills germs break up fooddigest proteinsstore food

pancreasproduces enzymes to digest proteins & starch

liverproduces bile

- stored in gall bladderbreak up fats

mouthbreak up foodmoisten food digest starchkill germs

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Digestive enzymes

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Absorption by Small Intestines• Absorption through villi & microvilli

– finger-like projections• increase surface area for absorption

Ooooh…Structure-Function

theme!

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stomachkills germs break up fooddigest proteinsstore food

small intestinesbreakdown food

- proteins- starch- fats

absorb nutrients

pancreasproduces enzymes to digest proteins & carbs

liverproduces bile

- stored in gall bladderbreak up fats

large intestinesabsorb water

mouthbreak up foodmoisten food digest starchkill germs

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Large intestines (colon)• Function

– re-absorb water• use ~9 liters of water every

day in digestive juices• > 90% of water reabsorbed

– not enough water absorbed back to body

» diarrhea – too much water

absorbed back to body» constipation

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Flora of large intestines

• Living in the large intestine is a richflora of harmless, helpful bacteria– Escherichia coli (E. coli)

• a favorite research organism– bacteria produce vitamins

• vitamin K; biotin, folic acid & other B vitamins– generate gases

• by-product of bacterial metabolism

• methane, hydrogen sulfide

You’ve gotcompany!

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Rectum • Last section of colon (large intestines)

– eliminate feces• undigested materials

– extracellular waste» mainly cellulose from plants» roughage or fiber

• salts• masses of

bacteria

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Appendix

Vestigial organ

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2006-2007

Animal NutritionVariations, Adaptations & Regulation

This obese mouse (L) has defect in gene which normally produces leptin, an appetite-regulating protein.

Many herbivores have diets deficient in mineral salts. Must find other sources = salt licks, chewing on bones

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Energy budget

food intake

basal (resting) metabolism

temperature regulation

activity

repair growth reproduction

ATPproductio

n {synthesi

s { glycogen fat

storage {

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Energy storage

• In humans– glycogen storage

• glucose polymer– in liver & muscle cells

• If glycogen stores are full & caloric intake still exceeds caloric expenditure– excess stored as fat– synthesis pathway

from acetyl coA

Why isglycogen highly

branched?

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Balancing calorie needs with intake

• When fewer calories are taken in than are expended, fuel is taken out of storage deposits & oxidized (digested)– breakdown (digest) glycogen

from liver & muscle cells– metabolize (digest) fat Just do it!

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Vegetarian diets• Need to make sure you get enough protein

– 20 amino acids to make protein• humans can synthesize 12 of the amino acids • 8 have to be eaten = “essential amino acids”

– Grains (like corn) have 6 (missing 2)– Beans (like soybean & red beans) have 6 (missing different 2)

• mix beans & grainsfor complete group of amino acids– rice & beans– taco/tortilla & beans– tofu & rice– peanut butter & breadWhat no fish!

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Eating a balanced diet

• What happens if an animal’s diet is missing an essential nutrient?– deficiency diseases

• scurvy — vitamin C (collagen production)• rickets — vitamin D (calcium absorption)• blindness — vitamin A (retinol production)• anemia — vitamin B12 (energy production)• kwashiorkor — protein

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Different diets; different bodies• Adaptations of herbivore vs. carnivore

– specialization in teeth– length of digestive system– number & size of stomachs

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Teeth

• Carnivore– sharp ripping teeth– “canines”

• Herbivore– wide grinding

teeth– molars

• Omnivore– both kinds of teeth

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Length of digestive system• Carnivores

– short digestive system

• protein easier to digest than cellulose

• Herbivores & omnivores– long digestive

system• more time to

digest cellulose• symbiotic

bacteria in gut

Rememberthe rabbits,

George!

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Symbiotic organisms

Ruminantsadditional mechanical digestion by chewing food multiple times after mixing it with enzymes

• How can cows digest cellulose efficiently?– symbiotic bacteria in stomachs help digest cellulose-rich

meals– rabbit vs. cow adaptation: eat feces vs. chew cud

ruminantcaprohagy

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Liver

Gallbladder

DuodenumPancreas

Stomach

Proteins

Gastrin

Acinarcells

Regulation of Digestion

Coordination of nervous system & endocrine system

HClPepsin

+ –

CCK

–Secretin

Chiefcells

Parietalcells

+

+

+

–Gastric

inhibitorypeptide

+

+

Fats

Bile

EnzymesBicarbonate

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Quick Check: Make Sure You Can1. Relate the structure and function of animal

digestive systems to their role in nutrition.2. Label/Identify all organs that play major roles

in the digestive system.3. Provide at least three examples of physical

and chemical digestion and their locations.4. Explain the causes of digestive system

disruptions and how disruptions of the digestive system can lead to disruptions of homeostasis.

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Plant Nutrition

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Nutritional needs• Autotrophic does not

mean autonomous– plants need…

• sun as an energy source

• inorganic compounds as raw materials

– water (H2O)

– CO2

– minerals

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For what & from where?

C macromolecule synthesis CO2

O macromolecule synthesis CO2

H macromolecule synthesis & proton pumps H2O

N protein & nucleic acid synthesis soil

P nucleic acids, ATP, phospholipids soil

K stomate control, water balance soil

Ca cell wall & membrane structure, regulation soil

Mg chlorophyll soil

S proteins, enzymes soil

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Macronutrients• Plants require these nutrients in relatively

large amounts– C, O, H, N, P, K, Ca, Mg, S

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Micronutrients• Plants require in very small amounts

– Cl, Fe, Mn, Bo, Zi, Ni, Mb– primarily cofactors for enzyme function

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Nutrient deficiencies• Lack of essential nutrients

– exhibit specific symptoms• dependent on

function of nutrient• dependent on

solubility of nutrient

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Magnesium deficiency• Symptoms

– chlorosis = yellowing of leaves– Why? What is magnesium’s function?

Take 2 fertilizer pellets

& call me in the morning

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Chlorophyll

Why does magnesium deficiency cause chlorosis?

The chlorosis shows up in older leaves first, because plant moves Mg+ to newer leaves. Why?

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Nitrogen uptake• Nitrates

– plants can only take up nitrate (NO3-)

• Nitrogen cycle by bacteria– trace path of nitrogen fixation!

What will the plant use N for?

root

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Soybean root nodules• N fixation by Rhizobium bacteria

– symbiotic relationship with bean family (legumes)

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Parasitic plants

• tap into host plant vascular systemIndian pipe

Mistletoe

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Carnivorous plants

Are they really carnivores?

Pitcher plantVenus fly trapSundew

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Hungry for Information?Ask Questions!

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Quick Check: Make Sure You Can1. Explain the function of major nutrients in

plant physiology.2. Relate the structure and function of plants to

the nutritional process.3. Explain the roles of symbiosis and parasitism

in plant nutrition.4. Compare the nutritional systems of plants

and animals.