ANIMAL CELLS AND TISSUES Lecture notes.pdf

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Animal Cell and Tissues Page 1 ANIMAL CELLS AND TISSUES by Michael J. Farabee, Ph.D., Estrella Mountain Community College, updated 12/06 Organization of the Animal Body Animals are multicellular heterotrophs whose cells lack cell walls . At some point during their lives, all animals are capable of movement, although not all animals have muscles they use for this. In the most commonly encountered animals, the mobile stage is the adult, although some animals (such as corals and sponges) have sessile (or nonmobile) adult phases and mobile juvenile forms. Both animal and plant evolutionary history show the development of multicellularity and the move from water to land (as well as a secondary adaptation back to water, for example dolphins, whales, duckweed, and elodea). Animals developed external or internal skeletons to provide support, skin to prevent or lessen water loss, muscles that allowed them to move in search of food, brains and nervous systems for integration of stimuli, and internal digestive systems . Organs in animals are composed of a number of different tissue types. For example, the stomach shown in Figure 1, has epithelial tissue making linings and secreting gastric juices, connective tissues Figure 1. Cells and tissues that comprise the stomach. Image from Purves et al., Life: The Science of Biology , 4th Edition, by Sinauer Associates (www.sinauer.com ) and WH Freeman (www.whfreeman.com ), used with permission.

description

Description of different animal cells and tissues.

Transcript of ANIMAL CELLS AND TISSUES Lecture notes.pdf

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Animal Cell and Tissues Page 1

ANIMAL CELLS AND TISSUES

by Michael J. Farabee, Ph.D., Estrella Mountain Community College, updated 12/06

Organization of the Animal Body

Animals are multicellular heterotrophs whose cells lack cell walls. At some point

during their lives, all animals are capable of movement, although not all animals have

muscles they use for this. In the most commonly encountered animals, the mobile

stage is the adult, although some animals (such as corals and sponges) have sessile (or

nonmobile) adult phases and mobile juvenile forms. Both animal and plant

evolutionary history show the development of multicellularity and the move from

water to land (as well as a secondary adaptation back to water, for example dolphins,

whales, duckweed, and elodea).

Animals developed external or internal skeletons to provide support, skin to prevent

or lessen water loss, muscles that allowed them to move in search of food, brains and

nervous systems for integration of stimuli, and internal digestive systems.

Organs in animals are composed of a number of different tissue types. For example,

the stomach shown in Figure 1, has epithelial tissue making linings and secreting

gastric juices, connective tissues

Figure 1. Cells and tissues that comprise the stomach. Image from Purves et al., Life:

The Science of Biology, 4th Edition, by Sinauer Associates (www.sinauer.com) and

WH Freeman (www.whfreeman.com), used with permission.

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Plants are simpler organisms than animals, having three organ systems and fewer

organs than do vertebrate animals. Organs are composed of tissues, which are in turn

composed of cells. Plants have three tissue types: ground, dermal, and vascular.

Animals have four: epithelial, connective, muscle, and bone.

Epithelial Tissue

Epithelial tissue covers body surfaces and lines body cavities. Functions include

lining, protecting, and forming glands. Three types of epithelium occur:

• Squamous epithelium is flattened cells.

• Cuboidal epithelium is cube-shaped cells.

• Columnar epithelium consists of elongated cells.

Any epithelium can be simple or stratified. Simple epithelium has only a single cell

layer. Stratified epithelium has more than one layer of cells. Pseudostratified

epithelium is a single layer of cells so shaped that they appear at first glance to form

two layers.

Figure 2. Cuboidal epithelium. The image is cropped from Loyola

University's LUMEN site at

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Animal Cell and Tissues Page 3

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl1-04.jpg.

Note the single layer of simple cuboidal epithelium lining either side of a

tubule.

Figure 3. Epithelium lining the intestine of a rat, as seen with SEM. This

image is from http://130.102.208.100/FMRes/FMPro?-

db=images.fp3&key=32816&-img, used by permission of Nanoworld.

Figure 4. Columnar epithelial cells. The above image is cropped

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and modified from Loyola University's LUMEN site at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl1-

12.jpg. Note: I have outlined one of the columnar epithelium cells.

Functions of epithelial cells include:

• movement materials in, out, or around the body.

• protection of the internal environment against the external environment.

• Secretion of a product.

Glands can be single epithelial cells, such as the goblet cells that line the intestine.

Multicellular glands include the endocrine glands. Many animals have their skin

composed of epithelium. Vertebrates have keratin in their skin cells to reduce water

loss. Many other animals secrete mucus or other materials from their skin, such as

earthworms do.

Figure 5. Glandular epithelium. The image is from Loyola

University's LUMEN site at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl1-

24.jpg).

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Connective Tissue

Connective tissue serves many purposes in the body:

• binding

• supporting

• protecting

• forming blood

• storing fats

• filling space

Connective cells are separated from one another by a non-cellular matrix. The matrix

may be solid (as in bone), soft (as in loose connective tissue), or liquid (as in blood).

Two types of connective tissue are Loose Connective Tissue (LCT) and Fibrous

Connective Tissue (FCT). Fibroblasts (LCT) are separated by a collagen fiber-

containing matrix. Collagen fibers provide elasticity and flexibility. LCT occurs

beneath epithelium in skin and many internal organs, such as lungs, arteries and the

urinary bladder. This tissue type also forms a protective layer over muscle, nerves,

and blood vessels.

Figure 6. Adipose tissue, a type of connective tissue. The image is

cropped from Loyola University's LUMEN page at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl2-

11.jpg.

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Adipose tissue, shown in Figure 6, has enlarged fibroblasts storing fats and reduced

intracellular matrix. Adipose tissue facilitates energy storage and insulation.

Fibrous Connective Tissue has many fibers of collagen closely packed together. FCT

occurs in tendons, which connect muscle to bone. Ligaments are also composed of

FCT and connect bone to bone at a joint.

Cartilage and bone are "rigid" connective tissues. Cartilage, shown in Figure 7, has

structural proteins deposited in the matrix between cells. Cartilage is the softer of the

two "rigid" connective tissues. Cartilage forms the embryonic skeleton of vertebrates

and the adult skeleton of sharks and rays. It also occurs in the human body in the ears,

tip of the nose, and at joints such as the knee and between bones of the spinal column.

Figure 7. Cartilage, a type of "soft" connective tissue. The image is

cropped from Loyola University's LUMEN page at http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl4A-

36.jpg.

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Bone, shown in Figure 8, has calcium salts in the matrix, giving it greater rigidity and

strength. Bone also serves as a reservoir (or sink) for calcium. Protein fibers provide

elasticity while minerals provide elasticity. Two types of bone occur. Dense bone has

osteocytes (bone cells) located in lacunae connected by canaliculi. Lacunae are

commonly referred to as Haversian canals. Spongy bone occurs at the ends of bones

and has bony bars and plates separated by irregular spaces. The solid portions of

spongy bone pick up stress.

Figure 8. Bone. The first image of bone is cropped from Loyola University's LUMEN

page at http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl4A-40.jpg.

Note the haversian canal and surrounded by osteocytes and a mineralized matrix. The

second image shows the structure and vascularization of bone. Image from Purves et

al., Life: The Science of Biology, 4th Edition, by Sinauer Associates

(www.sinauer.com) and WH Freeman (www.whfreeman.com), used with permission.

Blood is a connective tissue of cells separated by a liquid (plasma) matrix.

Illustrations of blood cells are shown in Figure 9. Two types of cells occur. Red blood

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cells (erythrocytes) carry oxygen. White blood cells (leukocytes) function in the

immune system. Plasma transports dissolved glucose, wastes, carbon dioxide and

hormones, as well as regulating the water balance for the blood cells. Platelets are cell

fragments that function in blood clotting.

Figure 9. Elements of the blood. The left image below is cropped from Loyola

University's LUMEN site at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl2B-51.jpg. Note the

red blood cells and the single neutrophil. The right image below is cropped from

Loyola University's LUMEN site at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl2B-64.jpg.

Erythrocytes as seem with the SEM. The bottom image is human red blood cells,

platelets and T-lymphocyte (erythrocytes = red; platelets = yellow; T-lymphocyte =

light green) (SEM x 9,900). This image is copyright Dennis Kunkel at

www.DennisKunkel.com, used with permission.

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Muscle Tissue

Muscle tissue facilitates movement of the animal by contraction of individual muscle

cells (referred to as muscle fibers). Three types of muscle fibers occur in animals (the

only taxonomic kingdom to have muscle cells):

• skeletal (striated)

• smooth

• cardiac

Muscle tissue and organization is shown in Figure 10.

Figure 10. Organization of muscle tissue. Images from Purves et al., Life: The Science

of Biology, 4th Edition, by Sinauer Associates (www.sinauer.com) and WH Freeman

(www.whfreeman.com), used with permission.

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Muscle fibers are multinucleated, with the nuclei located just under the plasma

membrane. Most of the cell is occupied by striated, thread-like myofibrils. Within

each myofibril there are dense Z lines. A sarcomere (or muscle functional unit)

extends from Z line to Z line. Each sarcomere has thick and thin filaments. The thick

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filaments are made of myosin and occupy the center of each sarcomere. Thin

filaments are made of actin and anchor to the Z line.

Skeletal (striated) muscle fibers, shown in Figure 11, have alternating bands

perpendicular to the long axis of the cell. These cells function in conjunction with the

skeletal system for voluntary muscle movements. The bands are areas of actin and

myosin deposition in the cells.

Figure 11. Striated muscle cells. The left image of striated muscle fibers is cropped

from Loyola University's LUMEN site at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl3A-45.jpg. The right

image is from http://130.102.208.100/FMRes/FMPro?-

db=images.fp3&key=32948&-img.

Smooth muscle fibers, shown in Figure 12, lack the banding, although actin and

myosin still occur. These cells function in involuntary movements and/or autonomic

responses (such as breathing, secretion, ejaculation, birth, and certain reflexes).

Smooth muscle fibers are spindle shaped cells that form masses. These fibers are

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components of structures in the digestive system, reproductive tract, and blood

vessels.

Figure 12. Smooth muscle cells. The image of smooth muscle cells is cropped from

Loyola University's LUMEN site at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl3A-42.jpg.

Cardiac muscle fibers are a type of striated muscle found only in the heart. The cell

has a bifurcated (or forked) shape, usually with the nucleus near the center of the cell.

The cells are usually connected to each other by intercalated disks, as shown in Figure

13.

Figure 13. Cardiac muscle cells. The top image of cardiac muscle cells is cropped

from Loyola University's LUMEN site at

http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl3A-48.jpg. Note the

dark band of the intercalated disk that separates two muscle cells. The bottom image

is of a heart muscle cell (nucleus, mitochondria, actin-myosin) (TEM x15,400). This

image is copyright Dennis Kunkel at www.DennisKunkel.com, used with permission.

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Nervous Tissue

Nervous tissue, shown in Figure 14, functions in the integration of stimulus and

control of response to that stimulus. Nerve cells are called neurons. Each neuron has a

cell body, an axon, and many dendrites. Nervous tissue is composed of two main cell

types: neurons and glial cells. Neurons transmit nerve messages. Glial cells are in

direct contact with neurons and often surround them.

Figure 14. Organization of a neutron. Image from Purves et al., Life: The Science of

Biology, 4th Edition, by Sinauer Associates (www.sinauer.com) and WH Freeman

(www.whfreeman.com), used with permission.

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The neuron is the functional unit of the nervous system. Humans have about 100

billion neurons in their brain alone! While variable in size and shape, all neurons have

three parts. Dendrites receive information from another cell and transmit the message

to the cell body. The cell body contains the nucleus, mitochondria and other

organelles typical of eukaryotic cells. The axon conducts messages away from the cell

body. Neurons are shown in Figure 15.

Figure 15. Neurons. The left image of large multipolar neuron (center of image) is

cropped from Loyola University's LUMEN site at http://www.meddean.luc.edu/lumen/MedEd/Histo/HistoImages/hl3-03.jpg. The right

image shows Pyramidal Neurons from the Central Nervous System (SEM x3,960).

This image is copyright Dennis Kunkel at www.DennisKunkel.com, used with

permission.

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Learning Objectives

• Be able to list the major functions of each of the four major animal tissue types.

• Distinguish between simple and stratified epithelial tissue.

• Compare and contrast the different types of connective tissues: loose, dense, fibrous,

cartilage, bone, blood, adipose. Be able to list the function of each type.

• Know the three types of muscle and be able to differentiate them visually and according

to their functions.

• Be able to diagram a typical neuron and its three areas: dendrite, axon, and cell body.

• Know the characteristics of the various types of animal tissues. Learn the types of cells

that compose each tissue type and be able to give some examples of organs that contain

significant amounts of each tissue type.

• Detail the functions carried out by epithelial tissue and state the general location of each

type.

• Be able to discuss the meaning of the term gland, cite three examples of glands, and state

the extracellular products secreted by each.

• Describe the basic features of connective tissue, and explain how the cells of this tissue

type enable connective tissue to carry out its various tasks.

• List three of the functions of blood.

• List two functions of bone and/or cartilage.

• Distinguish among skeletal, cardiac, and smooth muscle tissues in terms of location,

structure, and function.

• Muscle tissues contain specialized cells that can contract.

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• Neurons are organized as lines of communicaiton.

Term

Adipose

tissue actin axon blood bone

Cardiac

muscle

Cartilage Columnar

epithelium

Connective

tissue

Cuboidal

epithelium dendrites

endocrine

glands

Epithelial

tissue

erythrocytes Fibroblasts

Fibrous

Connective

Tissue (FCT)

Glial cells keratin

leukocytes Ligaments

Loose

Connective

Tissue (LCT)

mucus

Muscle

tissue

myofibrils

myosin Nervous tissue neurons plasma Platelets sarcomere

Simple

epithelium

Skeletal

(striated)

muscle

Smooth muscle

Squamous

epithelium

Stratified

epithelium tendons

Review Questions

1. Which of these is not an animal tissue? a) connective; b) xylem; c) epithelial; d) nervous

ans is b

2. Tissues are made of _______. a) groups of cells that perform a different set of functions;

b) collections of cells that perform similar or related functions; c) subellular structures

that aid in the performance of the cell's role; d) none of these ans is b

3. Which of these is NOT a function of epithelial tissue? a) covering surfaces; b) secretion;

c) support of the body; d) lining internal exchange areas ans is c

4. Layered epithelial tissue is referred to as which of these? a) squamous; b) stratified; c)

voluntary; d) pseudostratified ans is d

5. Which of these cell types covers the inside of the mouth? a) squamous epithelium; b)

cartilage; c) blood; d) cuboidal epithelium ANS is a

6. Protection of the body from infectious organisms is accomplished by which of these

tissues? a) bone; b) muscle; c) nerve; d) blood ANS is d

7. Linking of bone to bone in a skeletal system is accomplished by which of these tissues?

a) epithelial; b) connective; c) muscle; d) nervous ANS is b

8. Cells that line the tubules in the kidney make up which of these tissues? a) adipose; b)

squamous epithelium; c) cuboidal epithelium; d) stratified epithelium ANS is c

9. The storage of fat is accomplished by which of these cell types? a) adipose; b) squamous

epithelium; c) cuboidal epithelium; d) stratified epithelium ANS is a

10. Glands are composed of which of these tissue types? a) epithelium; b) connective; c)

muscle; d) nervous ANS is a

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11. Hard parts of the body would be made of which of these cell/tissue types? a) blood; b)

bone; c) muscle; d) nerves ANS is b

12. Bone acts as a reservoir for which of these elements? a) carbon; b) nitrogen; c) calcium;

d) hydrogen ANS is c

13. The major function of bone is ___. a) covering body surfaces; b) support; c) movement;

d) integration of stimulus ANS is b

14. New blood cells are formed in the ___. a) matrix; b) bone marrow; c) liver; d) adipose

cells AMS is b

15. The blood cells that transport oxygen within the body are the ___. a) macrophages; b)

erythrocytes; c) platelets; d) leukocytes ANS is b

16. The liquid part of the blood is ___. a) plasma; b) adipose; c) cartilage; d) platelets ANS is

a

17. When you move your arm to use your computer mouse, which of these muscle cell types

is involved? a) cardiac; b) skeletal; c) smooth ANS is b

18. Contraction of your heart is accomplished by which of these cell types? a) cardiac; b)

skeletal; c) smooth ANS is a

19. Contractions of the uterus during birth are accomplished by which of these cell types? a)

cardiac; b) skeletal; c) smooth ANS is c

20. The junctions between nerve cells are known as ___. a) gap junctions; b) synapses; c)

tight junctions; d) villi ANS is b

21. Transmission of the nerve message within the neuron is ___ in nature. a) chemical b)

electrical ANS is b

Links

• Histology resources from University of Kansas Medical School.

• University of Pennsylvania Histology Homepage Organized by organ system or tissue

type, this site presents many useful images in an esay to use frame format.

• Muscle Cell Types from Human Anatomy On-line

• Histology Lab Orientation Online lectures and quizzes for the introductory histology as

well as more advanced histology students.

• Histology entry at Wikipedia offers a discussion of aspects of histology.

• Internet Atlas of Histology, COM-UIUC More histology than you might want, but a

superb resource open to students and interested parties, featuring a frame-based atlas with

zoomable images that simulate the microscope experience!

Text ©1992, 1994, 1997, 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2007 by M. J. Farabee, all

rights reserved.

Email: [email protected]

www.emc.maricopa.edu /faculty/farabee/biobk/BioBookAnimalTS.html