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ANATOMY AND PHYSIOLOGY Functions of the gastrointestinal (GI) system:
* Process food substances
* Absorb the products of digestion into the blood
* Excrete unabsorbed materials
* Provide an environment for microorganisms to
synthesize nutrients, such as vitamin K
Mouth Contains the lips, cheeks, palate, tongue, teeth,
salivary glands, muscles and maxillary bones
• Saliva contains the amylase enzyme (ptyalin)
that aids in digestion
• Mechanical and chemical digestion originate here
Esophagus A muscular tube, about ten inches long
Carries food from the pharynx to the stomach
Upper esophageal sphincter (UES)
Lower esophageal sphincter (LES)
Stomach A hollow muscular pouch
Secretes pepsin, renin, lipase, mucus and hydrochloric
acid for digestion
• Mixes and stores chyme
• Secretes intrinsic factor necessary for absorption of
vitamin B12
Small Intestine (3) Main Functions:
Movement (mixing & peristalsis)
Digestion of food
Absorption of nutrients
Small Intestine Duodenum: Contains the openings of the bile and
pancreatic ducts and is approximately 12 inches long
Jejunum: Approximately 8 feet long
Ileum: Approximately 12 feet long
Terminates into the cecum
Small Intestine Chyme, in liquid or semiliquid form, enters the
duodenum through the pyloric sphincter
Bile and pancreatic secretions enter the duodenum through the common bile duct
Large Intestine Consists of the cecum, colon, rectum and anus
Absorbs fluids, synthesizes Vitamin K using intestinal bacteria and stores fecal material
Chyme becomes more solid as the intestinal wall of the colon absorbs water and wastes
Defecation is the movement of feces from the rectum through the anal sphincter
Approximately 5 to 6 feet in length
Assessment Findings History
Culture
Inadequate diet
Change in bowel habits
Constipation
Diarrhea
Flatus
Assessment Findings Cont. Indigestion/heartburn
Abdominal pain
Dysphagia
Loss of appetite
Unintentional weight loss or gain
Objective Data Associated With GI Disorders
Weight changes
Abnormal color and consistency of stool
Melena
Clay-colored stool
Frothy stools
Occult blood in stool
Abnormal bowel sounds
Objective Data Associated With GI Disorders
Abdominal distention
Rectal bleeding
Jaundice
Edema
Hematemesis
Anorexia
Changes in skin
Diagnostic Tests And Procedures Upper GI tract study (barium swallow):
Teaching preprocedure ?
Teaching postprocedure?
Diagnostic Tests And Procedures Lower GI tract study (barium enema)
Teaching preprocedure?
Teaching postprocedure?
Diagnostic Procedures Upper GI fiberoscopy:
Esophagogastroduodenoscopy (EGD)
Following sedation, an endoscope is passed down the esophagus to view the gastric wall, sphincters and duodenum; tissue specimens can be obtained
Diagnostic Procedures Pre-procedure:
NPO for 6 to 8 hours prior to the test
A local anesthetic (spray or gargle) is administered along with midazolam (Versed) which provides conscious sedation and relieves anxiety just before the scope is inserted
Atropine may be administered to reduce secretions and glucagon may be administered to relax smooth muscle
Diagnostic Procedures Client is positioned on the left side to facilitate saliva
drainage and to provide easy access of the endoscope
Airway patency is monitored during the test and pulse oximetry is used to monitor oxygen saturation; emergency equipment should be readily available
Diagnostic Procedures Post-procedure:
NPO until the gag reflex returns (1 to 2 hours)
Monitor for signs of perforation (pain, bleeding, unusual difficulty in swallowing, elevated temperature)
Maintain bed rest for the sedated client until alert
Lozenges, saline gargles, or oral analgesics can relieve minor sore throats after the gag reflex returns
Diagnostic Procedures Proctoscopy and Sigmoidoscopy: Use of a flexible
scope to examine the rectum and sigmoid colon; client is placed on the left side with the right leg bent and placed anteriorly
Biopsies and polypectomies can be performed
Pre-procedure: Enemas until the returns are clear
Post-procedure: Monitor for rectal bleeding and signs of perforation
Diagnostic Procedures Fiberoptic Colonoscopy:
A fiberoptic endoscopy study in which the lining of the large intestine is visually examined; biopsies and polpectomies can be performed
Cardiac and respiratory function is monitored continuously during the test
Performed with the client lying on the left side with the knees drawn up to the chest; position may be changed during the test to facilitate passing of the scope
Diagnostic Procedures Pre-procedure:
Adequate cleansing of the colon is necessary as prescribed by the physician
A clear liquid diet is started 12-24 hours before procedure
NPO 6-8 hours before procedure
Midazolam (Versed) IV is administered to provide sedation
Diagnostic Procedures Post-procedure:
Provide bed rest until alert
Monitor vital signs
Monitor for signs of perforation
Instruct the client to report any bleeding to the physician
Instruct client may experience abdominal fullness and cramping even a few hours after
Diagnostic Procedures Laparoscopy:
Performed with a fiberoscopic laparoscope that allows direct visualization of organs and structures within the abdomen; biopsies may be obtained
Diagnostic Procedures Paracentesis:
Transabdominal removal of fluid from the peritoneal cavity for analysis
Diagnostic Procedures Pre-procedure:
Obtain informed consent
Void prior to the start of procedure to empty bladder and to move bladder out of the way of the paracentesisneedle
Measure abdominal girth, weight and baseline vital signs
Client is positioned upright on the edge of the bed with the back supported and the feet resting on a stool
Diagnostic Procedures Post-procedure:
Monitor vital signs
Measure fluid collected, describe and record
Label fluid samples and send to the lab for analysis
Apply a dry sterile dressing to the insertion site; monitor site for bleeding
Diagnostic Procedures Measure abdominal girth and weight
Monitor for hypovolemia, electrolyte loss, mental status changes or encephalopathy
Monitor for hematuria resulting from bladder trauma
Instruct the client to notify the physician if the urine becomes bloody, pink or red
Abdominal Assessment Inspect for skin color, symmetry and abdominal
distention
Auscultate for bowel sounds
Percuss for air or solids
Palpate for tenderness
Bowel Sounds Auscultate bowel sounds before percussion and
palpation
Normal bowel sounds occur 5 to 30 times a minute or every 5 to 15 seconds
Auscultate in all abdominal quadrants
Listen at least one full minute in each quadrant before assuming sounds are absent
GI Pharmacologic Management Proton Pump Inhibitors
Antacids
Histamine H2 Receptor Antagonists
Anticholinergics
Mucosal Barrier Fortifiers/Cytoprotectants
Prostaglandin Analogues
Antiemetics
Laxatives/Bowel Cleansers *Antimicrobials
Antidiarrheals *Prokinetics
Gastroesophageal Reflux Disease (GERD)
Definition:
Backflow (reflux) of gastric or duodenal contents into the esophagus and past the lower esophageal sphincter(LES)
GERD (Etiology) Impaired LES
Increased intra-abdominal pressure (obesity, pregnancy, constricting waistline, bending over and ascites)
Alcohol ingestion
Smoking
GERD (Etiology) Cont. Gastric distention from large meals
Delayed gastric emptying
Certain foods
Nasogastric tube placement
Meds- calcium channel blockers, anticholinergics and nitrates
GERD Pathophysiology Reflux occurs when LES pressure is deficient or when
pressure within the stomach exceeds LES pressure (heartburn)
Acidic contents cause injury and inflammation to esophageal mucosa
GERD (Assessment Findings) Dyspepsia (pyrosis or heartburn) in epigastric region,
may radiate to jaw or arms, occurs after meals
Pain worsens with lying down or bending over
Hypersalivation
Regurgitation
Dysphagia and Odynophagia
Belching
Nausea
GERD Diagnostic Tests Esophageal acidity 24 hour test- reveals reflux
Endoscopy- allows visualization and confirmation of pathologic changes in the mucosa
Esophageal manometry- evaluates LES pressure
GERD Medical Management:
Diet- small frequent meals, avoid meals before bedtime
Diet therapy
Position upright during and after meals, sleep with HOB elevated
Smoking/Alcohol Cessation
GERD (Drug Therapy) Inhibit gastric acid secretion
Accelerate gastric emptying
Protect the gastric mucosa
Examples:
Antacids- Maalox
H2-antagonists- Tagamet, Zantac
Proton pump inhibitors- Prilosec, Prevacid
Prokinetics- Reglan
GERD Procedures Endoscopic therapies:
Stretta procedure
BESS procedure
Surgical Procedure:
Laparoscopic Nissen Fundoplication (LNF)
Hiatal Hernia Also known as esophageal or diaphragmatic hernia
A portion of the stomach protrudes or herniatesthrough the diaphragm and into the thorax
It results from weakening of the muscles of the diaphragm and is aggravated by factors that increase abdominal pressure, such as pregnancy, ascites, obesity, tumors and heavy lifting
Sliding vs. Rolling
Hiatal Hernia Complications include ulceration, hemorrhage,
regurgitation and aspiration of stomach contents, strangulation, and incarceration of the stomach in the chest with possible necrosis or peritonitis
Hiatal Hernia Assessment Findings:
Heartburn
Regurgitation or vomiting
Dysphagia
Feeling of fullness
Pain
Belching
Hiatal Hernia Implementation:
Medical and surgical management is similar to that for GERD
Provide small, frequent meals and minimize the amount of liquids
Advise the client not to recline for several hours after eating
Nissen procedure, if needed
Esophageal Cancer Usually squamous cell or adenocarcinoma
Commonly found in the upper third of the esophagus
Early spread to the lymph nodes is common
Esophageal Cancer (Silent Tumor) Contributing factors include:
Heavy use of tobacco and alcohol
Chronically low intake of fresh fruits and vegetables
Chronic irritation- GERD or chronic gastritis
Obesity
Malnutrition
Esophageal Cancer Assessment Findings:
Dysphagia
Odynophagia
Feeling of food sticking in throat
Nocturnal aspiration
Regurgitation
Esophageal Cancer Assessment Findings Cont.:
Eventually inability to swallow liquids
Changes in bowel habits
Chronic cough with increasing secretions
Nausea/Vomiting
Anorexia
Weight loss
Esophageal Cancer Treatment:
Nutrition therapy
Swallowing therapy
Antineoplastic agents, radiation or combo
Photodynamic therapy
Esophageal dilation
Surgery to resect tumor
Gastrotomy to maintain nutrition
Esophageal Cancer Surgical Management:
Esophagectomy- the removal of all or part of the esophagus
Esophagogastrostomy- the removal of part of the esophagus and proximal stomach
Esophageal Cancer Preoperative Care: (Teaching)
Stop smoking
Nutritional support (supplementation)
Monitor weight
Monitor I & O
Meticulous oral care
TCDB
Esophageal Cancer Preoperative Care: (Teaching) Cont.
Post-op respiratory care
The number and sites of all incisions and drains
The placement of a jejunostomy tube
May need chest tubes
The need for IV infusion
The purpose of the NG tube
Gastritis Inflammation of the stomach or gastric mucosa
Acute: caused by the ingestion of food contaminated with disease-causing microorganisms or food that is irritating or too highly seasoned, the overuse of aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDS), excessive alcohol intake, local irritation from radiation therapy, caffeine, the bacteria Helicobacter Pylori
Gastritis Chronic: caused by benign or malignant ulcers, or by
the bacteria Helicobacter pylori; may also be caused by autoimmune diseases, dietary factors, medications, alcohol, smoking, or radiation
The result is hypermotility of the GI tract, leading to altered secretions of fluids and electrolytes
Increased risk for gastric cancer
Gastritis (Acute) Assessment Findings:
Rapid onset of epigastric pain or discomfort
Nausea and vomiting
Hematemesis
Gastric hemorrhage
Dyspepsia
Anorexia
Gastritis (Chronic) Assessment Findings:
Vague complaint of epigastric pain that is relieved by food
Anorexia, Nausea or Vomiting
Intolerance of fatty and spicy foods
Vitamin B12 deficiency/pernicious anemia
Gastritis Diagnostic Test:
EGD with biopsy
Surgical Intervention- None
* Unless bleeding or ulceration (partial gastrectomy, pyloroplasty, vagotomy or total gastrectomy)
Gastric Surgery Descriptions:
Vagotomy- surgical ligation of the vagus nerve to decrease the secretion of gastric acid
Pyloroplasty- enlarges the pylorus to prevent or decrease pyloric obstruction, thereby enhancing gastric emptying
Gastroduodenostomy- (Billroth I)- surgical removal of the lower portion of the stomach with anastomosis of the remaining portion of the stomach to the duodenum
Gastric Surgery Gastrojejunostomy- (Billroth II)- partial gastrectomy
with remaining segment anastomosed to the jejunum
Esophagojejunostomy- (Total Gastrectomy)- surgical removal of the entire stomach with a loop of the jejunum anastomosed to the esophagus
Peptic Ulcer Disease (PUD) An ulceration in the mucosal wall of the stomach,
pylorus, duodenum, or esophagus, in portions that are accessible to gastric secretions; erosion may extend through the muscle
May be referred to as gastric, duodenal, or stress ulcers, depending on location
The most common peptic ulcers are gastric ulcers and duodenal ulcers
Peptic Ulcer Pathophysiology:
Increased emptying time of gastric acid from the gastric lumen into the small intestine causes an inflammatory reaction with tissue breakdown
Combination of hydrochloric acid and pepsin destroys gastric mucosa
Peptic Ulcer Causes:
Drug induced: NSAIDS, ASA, Corticosteroids, etc.
Infection- Helicobacter pylori
Smoking
Alcohol abuse
Gastritis
Caffeine
Stress
Gastric Ulcers Assessment Findings:
Gnawing, sharp pain in or left of the midepigastricregion 30-60 minutes after eating
Hematemesis
Pain that is increased from eating
Duodenal Ulcers Assessment Findings:
Burning pain one and a half to three hours after eating and during the night
Pain that is often relieved by eating
Melena
Peptic Ulcers Surgical Implementation:
Surgery is performed only if the ulcer is unresponsive to medications or if hemorrhage, obstruction, or perforation occurs
Gastrointestinal Bleeding Assessment Findings:
Coffee-ground vomitus
Tarry stools or frank blood in stools
Melena
Decreased B/P
Gastrointestinal Bleeding Assessment Findings Cont.:
Increased weak and thready pulse
Decreased HGB and HCT
Vertigo
Acute confusion (in older adults)
Dizziness
Syncope
Gastrointestinal Bleeding Common causes of upper GI bleeding:
Esophageal cancer
Esophageal varices
Gastritis
Gastric ulcer
Gastric cancer
Duodenal ulcer
Gastrointestinal Bleeding Common causes of lower GI bleeding:
Ulcerative colitis
Polyps
Colon cancer
Diverticulosis/Diverticulitis
Rectal cancer
Hemorrhoids
Peptic ulcer disease
Crohn’s disease
Gastrointestinal Bleeding Interventions:
Hypovolemia management
Bleeding reduction/Non-Surgical management:
Nasogastric tube placement
Saline/water lavage
Gastrointestinal Bleeding Interventions Cont.:
Endoscopic therapy (EGD)
Acid suppression
Surgical Management:
Minimally Invasive Surgery via Laparoscopy
vs. Conventional Surgery
Gastric Cancer Pathophysiology:
Unregulated cell growth and uncontrolled cell division result in the development of a neoplasm
Tumor usually develops in the distal third of stomach and metastasizes to the abdominal organs, lungs and bones
Most common neoplasm is adenocarcinoma
Gastric Cancer Causes:
Infection with H. pylori
High intake of salty and smoked foods
Chronic gastritis
Pernicious anemia
Gastric ulcer
Smoking and alcohol consumption
Gastric Cancer Assessment Findings: (Early)
Indigestion
Feeling of fullness
Epigastric, back, or retrosternal pain
Abdominal discomfort initially relieved with antacids
Gastric Cancer Assessment Findings: (Advanced)
Nausea and vomiting
Progressive weight loss
Palpable epigastric mass
Enlarged lymph nodes
Weakness and fatigue
Obstructive symptoms
Iron deficiency anemia
Gastric Cancer Nonsurgical Management:
Depends on stage of disease
Chemotherapy
Radiation
Side effects
Gastric Cancer Surgical Management:
Total gastrectomy
Partial gastrectomy
MIS (minimally invasive surgery)
Palliative resection
Preoperative Care/Teaching Patient and family teaching
Enteral supplements
TPN (Total Parenteral Nutrition)
Explain the post-op need for drainage tubes, surgical dressings, O2 therapy, IV therapy and pain control
Start IV
Administer pre-op meds
Insert foley catheter
Insert NG tube
Postoperative Care/Teaching Assess cardiac and respiratory status
Assess pain and administer meds as prescribed
Inspect surgical site
Reinforce turning, coughing and deep breathing
Administer IV fluids as prescribed
Semi-fowlers position
Assess for return of peristalsis
Postoperative Care/Teaching Cont. Activity as tolerated
Monitor VS, I&O, pulse ox, labs
Monitor NG drainage
Do not reposition or irrigate NG tube!
Weigh patient daily
Increase food intake gradually
Eat six small meals daily
Gastric Cancer Surgical Complications
Hemorrhage
Infection
Dehiscence
Disruption in patency of NG tube
Dumping syndrome
NG Tube Feedings Nausea, vomiting or bloating:
Large residuals- withhold or decrease feedings
Medications- review meds and consult MD
Rapid infusion rate- decrease rate
NG Tube Feedings Diarrhea:
Reduce rate
Administer at room temperature
Constipation:
Provide adequate hydration
Use formula with fiber
NG Tube Feedings Aspiration and gastric reflux:
Verify placement
Check residuals
Keep HOB elevated 30-40 degrees