Analysis of Bone Grafts and Bone Graft Substitutes Market

Growth Opportunities in Niche Emerging Areas

United States

NB90-54

2NB90-54

Research Team

Venkat RajanIndustry Manager

Medical Devices

Aarti ShettySenior Research Analyst

Medical Devices

Lead Analyst

Research Director

Daniel Ruppar Director of Research

Healthcare

Strategic Review Committee Leader

3NB90-54

Contents

Section Slide Numbers

Executive Summary 4

Market Overview 7

Total Market -

• External Challenges: Drivers and Restraints 10

• Forecasts and Trends 25

• Market Share and Competitive Analysis 33

Machined Bone Allograft Market 41

Standard Bone Allograft Market 52

Demineralized Bone Matrix (DBM) Segment 63

Bone Graft Substitutes Segment 75

Bone Morphogenetic Protein (BMP) Segment 91

Cell Based Matrices Segment 54

Platelet Concentration System Segment 116

The Last Word (Conclusions and Implications) 126

Appendix 130

4NB90-54

Executive Summary—CEO’s Perspective

2Rise in popularity of cell based

matrices dictates new market trend

3Differentiation in bone graft substitutes

market is becoming the most crucial

competitive factor

4Off-label use of bone graft material is

on the rise, resulting in stricter

guidelines for use

5Increases in reconstruction and spine

surgery demand use of advanced bone

grafts

1Declining growth in the bone

morphogenetic market is decreasing

overall market revenue

Source: Frost & Sullivan analysis.

5NB90-54

Market Segmentation

Bone Grafts and Bone Graft Substitutes Market: Market Segmentation, U.S., 2011

Source: Frost & Sullivan analysis.

Platelet Concentration System segment is treated as a separate segment in the study. The overall bone

grafts and bone graft substitute market revenue is not inclusive of the platelet concentration system market.

Demineralized

Bone Matrix

(DBM)

Bone Grafts and Bone Graft Substitutes Market

Bone Graft

Substitutes

Machined

Bone

Allograft

Bone

Morphogeneti

c Protein

(BMP)

Cell Based

Matrices

Platelet

Concentration

System

Standard

Bone

Allograft

6NB90-54

Market Overview—Key Questions This Study Will Answer

Is the bone grafts market growing, how long will it continue to grow and at what rate?

What are the primary drivers of market expansion and growth opportunities in large and small

segments of the market?

Which segments are expanding the most, and which are declining?

What type of regulations are affecting the market?

Are the products/services offered today meeting customer needs or is there additional development

needed?

How is the competition in the market? Are some companies poised for more growth than others?

Source: Frost & Sullivan analysis.

7NB90-54

Drivers and Restraints

Negative media literature about tissue recovery

deters widespread adoption of biologic products.

Federal cost-cutting measures and poor

reimbursement will negatively affect business and

financial decisions

Poor or lack of reimbursement for expensive

innovative technologies obviates technology

adoption

1–2 years 3–4 years 5 years

Increase in the number of orthopedic surgeries

leads to increased usage of bone grafts.

Advances in bone graft materials creates better

results and bolsters confidence

Room for innovative products creates low barriers

for enter in some niche markets

Increasing market competition promotes

differentiation of products

Mark

et

Dri

vers

Mark

et

Restr

ain

ts

Impact: High Medium Low

Bone Graft and Bone Graft Substitutes Market: Key Market Drivers and Restraints, U.S., 2012–2016

Source: Frost & Sullivan analysis.

8NB90-54

Market Engineering Methodology

One of Frost & Sullivan’s core deliverables

is its Market Engineering studies. They

are based on our proprietary Market

Engineering Methodology. This approach,

developed across the 50 years of

experience assessing global markets,

applies engineering rigor to the often

nebulous art of market forecasting and

interpretation.

A detailed description of the methodology

can be found here.

Source: Frost & Sullivan research.