AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY

JULY 3, 2009

VOLUME 284

NUMBER 27

JBC_070309_#27.indd 1JBC_070309_##27.indddd 11 6/9/09 10:04:20 AM66/9/9/0/09 10:04:20 AM4:20 AM

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The Journal of Biological ChemistryISSN 0021-9258 (print)ISSN 1083-351x (electronic)

GENERAL INFORMATION

Department of Health and Human Services National Institutes of Health

National Cancer Institute Division of Cancer Treatment and Diagnosis

Developmental Therapeutics Program Office of Associate Director

Opening Date: June 12, 2009 Closing Date: July 21, 2009

Announcement Numbers: NCI-09-326230-DE NCI-09-326230-MP

Special Assistant to the Associate Director for Developmental Therapeutics

Biologist/Pharmacologist/Chemist, GS-401/405/1320-14 The Developmental Therapeutics Program (DTP), Division of Cancer Treatment and Diagnosis (DCTD) of the National Cancer Institute is responsible for planning, directing and evaluating a collaborative, extramural, contract-supported program in anticancer drug development. The DTP promotes all aspects of the discovery and preclinical development of new compounds (small molecules, biologics, botanicals) as antineoplastic drugs. The DTP also provides drug development expertise to the NIH community through a pilot program called NIH RAID (Rapid Access to Intervention Development). Thus, drug development encompasses other therapeutics areas including cardiovascular, pulmonary, mental health, etc. We are recruiting for two Biologists, Chemists, and/or Pharmacologists to assist the DTP Associate Director in planning, implementing, evaluating, and communicating the scientific research and development projects of the DTP. The candidates must have the ability to organize, plan and accomplish project tasks in a timely and cost-effective manner. The candidates would serve as Special Assistants to the DTP Associate Director and contacts consist of NCI senior staff, officials in NIH, DHHS, representatives of Congress and outside organizations (academic, pharmaceutical/biotechnical, advocacy, media, public) to present data and information on NCI programs and activities. Project implementation and resource management involve major decisions and actions which have a direct and substantial effect on the organization. Qualifications Required: A Ph.D. degree in Biology, Chemistry (organic or medicinal), or Pharmacology is highly desirable. Candidates must have experience in evaluating complex programmatic resources, goals, strategies, policies, procedures, and requirements and demonstrated ability to summarize results and communicate, manage, and implement recommendations in a highly professional manner. Candidates must have working knowledge of current research and development methods and processes pertaining to the diagnosis, prevention, mitigation, or treatment of chronic and/or life threatening exposures, conditions, or diseases. Salary and Benefits: Total annual compensation range is $102,721 to $133,543 per annum. Various incentives may apply in individual circumstances, based on experience and expertise. Full Federal benefits including health and life insurance options, retirement, paid holidays, vacation and sick leave will be provided. Employer will assist with relocation costs. How to Apply: To obtain the mandatory application requirements and other necessary information, please visit: http://jobsearch.usajobs.opm.gov/a9nih.asp, Vacancy Announcement number, NCI-09-326230-DE or MP. For more information, contact Ms. Mary Lou Weathers at (301)402-5059 or weatherm@mail.nih.gov. Individuals interested to learn more about these positions are encouraged to contact:

Dr. Jerry Collins, Associate Director, DTP, DCTD, NCI 6130 Executive Boulevard, EPN, Room 8018

Rockville, MD 20852 Tel: (301)496-8720; Fax: (301)402-0831; Email: collinsje@mail.nih.gov.

DHHS, NIH and NCI are Equal Opportunity Employers.

A

Agostoni, Elena, 18167

Ailhaud, Gerard, 18282

Allen, Shelley J., 18424

Anesia, Rodica, 18282

Antonyak, Marc A., 17914

Araki, Wataru, 18493

Arner, Peter, 18282

Arumugam, Thiruma V.,18323

Asrani, Kaushal, 17947

Avery, Simon V., 17968

B

Bajpai, Saumendra, 18252

Barbour, Karen, 18292

Baumert, Thomas F., 18194

Belal, Cherine, 18323

Bennett, Jessica, 17947

Berger, Franklin G., 18292

Bernlohr, David A., 18347

Bezaire, Veronic, 18282

Bieberich, Erhard, 18033

Bielinska, Beata, 18115

Billett, Ellen, 18411

Boland, Coilin, 18218

Brady, Jacob P., 18537

Bramall, Neil, 18377

Brazier-Hicks, Melissa,17926

Brincat, Allison, 18515

Brooks, Yang S., 18033

Brosh, Robert M., Jr., 18458

Bryan, Keith E., 18260

Buchner, Claudia, 18228

Bunch, Josephine, 18377

C

Calligaris, Raffaella, 18167

Camerini-Otero, R. Daniel,18458

Caplen, Natasha J., 18085

Carlberg, Carsten, 18270

Carlsson, Steven K., 18143

Carnemolla, Alisia, 18167

Carretero-Ortega, Jorge,18334

Cerione, Richard A., 17914

Chan, Sic L., 18323

Chen, Jiandong, 18210

Chen, Junjie, 18302

Chen, Lihong, 18210

Chen, Shao-Hung, 18096

Chen, Wendy Yiting, 18007

Cheung, Peter Ching For,18047

Chigurupati, Srinivasulu,18323

Cho, Chao-Cheng, 17975

Choi, Won-Il, 17935

Chong, Han Chung, 18047

Chudakov, Dmitry M.,17902

Clewes, Oliver, 18424

Coffin, Stephanie R., 18390

Coppola, Domenico,18210

Coughlin, Michael D.,18424

Cox, Alan G., 18377

D

Dahl, Gerhard, 18143

Dai, Haiming, 18311

Dani, Christian, 18282

Das, Biswajit, 18545

Davies, Mark J., 18202

Dawbarn, David, 18424

Del Sal, Giannino, 18167

De Maso, Luca, 18167

de Rivero Vaccari, JuanPablo, 18143

Dolmer, Klavs, 17989

Dong, Jin-Tang, 18184

Dong, Xue-Yuan, 18184

Dowd, Diane R., 18174

Dressler, Gregory R., 18078

Drickamer, Kurt, 18537

D’Souza, David R., 17947

Dubiley, Svetlana A.,17902

Dusaban, Stephanie S.,17914

E

Edwards, Robert, 17926

Ellison, David H., 18471

Eoff, Robert L., 18434

Evans, Kathryn M., 17926

F

Fabrick, Jeff, 18401

Fagnant, Patricia M., 18244

Fahnestock, Margaret,18424

Fedorova, Olga S., 17902

Feng, Qiyu, 17914

Feng, Yunfeng, 18252

Fiermonte, Giuseppe,18152

Fiorentino, Maria, 18545

Fogelman, Alan M., 18292

Fossale, Elisa, 18167

Fu, Liezhen, 18545

Funabara, Daisuke, 18015

G

Gabibov, Alexander G.,17902

Gao, Zhanguo, 18368

García-Regalado,Alejandro, 18334

Geng, Liyi, 18236

Germack, Renee, 18411

Gershater, Markus C.,17926

Gettins, Peter G. W., 17989

Girousse, Amandine,18282

Goga, Andrei, 18515

Goh, Yan Yih, 18047

Goldblum, Simeon E.,17947

Gong, Eun-Yeung, 18021

Gordon, Jeffrey I., 18445

Graham, Alison I., 18377

Graham, Sarah A., 18537

Greenberg, Miriam L.,18106

Gregor, Martin, 18525

Grijalva, Victor, 18292

Groth, Georg, 18228

Guengerich, F. Peter,18434

Guo, Peng, 18184

Gupta, Ratna, 18481

Gutkind, J. Silvio, 18334

Guzman-Hernandez,María Luisa, 18334

H

Hallen-Adams, Heather E.,18070

Hama, Susan, 18292

Han, Young-Hoon, 18503

Hartshorne, David J., 18015

Hashimoto, Wataru, 18059

Hayes, Patti, 18218

He, Qing, 18368

Heidersbach, Amy, 18515

Hernandez-García,Ricardo, 18334

Hernandez-Negrete,Ivette, 18334

Heuser, John E., 18445

Heyes, Derren J., 18160

Holst, Otto, 18194

Holthuis, Joost C. M., 17956

Horiuchi, Dai, 18515

Hoshino, Tatsuya, 18493

Hsieh, Ju-Yi, 18096

Hsu, Ruby, 18515

Huang, Tzu-Hsuan, 18515

Huang, Ying, 18129

Huebner, Johannes,18194

Huen, Michael S. Y.,18302

Hung, Hui-Chih, 18096

Hung, Jacky, 18007

Hunt, Stuart, 18377

Hur, Man-Wook, 17935

I

Ioannou, Maria S., 18424

Itoh, Takafumi, 18059

J

Jegouzo, Sabine A. F.,18537

Jensen, Jan K., 17989

Jeon, Bu-Nam, 17935

Jocken, Johan, 18282

Johnson, Timothy, 18411

Jones, Tamara L., 18085

Jurat-Fuentes, Juan Luis,18401

K

Kabra, Neha, 18210

Kanoh, Satoshi, 18015

Kao, Yu-Yun, 17975

Kaufman, Randal J., 18202

Kaufmann, Scott H., 18311

Keane, Robert W., 18143

Kelly, Vincent P., 18218

Khozoie, Combiz, 17968

Kim, Jin-Hee, 18503

Kim, Myung-Hwa, 17935

Knorre, Dmitry G., 17902

Ko, Lan, 18033

Kolesnikov, Alexander V.,17902

Kostan, Julius, 18525

Kozyr, Arina V., 17902

Kranenburg, Tanya A.,18174

Krishnamurthy, Ranjini,18252

Kuznetsov, Nikita A., 17902

Kyriazis, George A., 18323

L

Langin, Dominique, 18282

Laurencikiene, Jurga,18282

Lebbink, Robert J., 18515

Lee, Hyun Joo, 18021

Lee, Kee-Ho, 18503

Lee, Keesook, 18021

Lee, Sun-Hee, 18311

Lefort, Corinne, 18282

Legerski, Randy J., 18236

Lenoir, Guillaume, 17956

Li, Baozong, 18210

Li, Bo, 17914

Li, Boyangzhi, 18194

Li, Guiling, 18106

Li, Zhenyu, 18210

Lian, Min, 17998

Lin, Feng, 18503

Linhardt, Robert J., 18194

Liu, Jie, 18471, 18503

Liu-Chen, Lee-Yuan, 18357

Lobo, Sandra, 18347

Locovei, Silviu, 18143

Loeb, Gabriel B., 18515

Lomas, David A., 18202

Longmore, Gregory D.,18252

Lorenzen, Marce D., 18401

Lortat-Jacob, Hugues,18411

Lu, Na, 18503

Lui, Ki, 18129

Luo, Hong, 18070

M

MacDonald, Marcy E.,18167

MacDonald, Paul N., 18174

MacRae, Ian J., 17897

Mairal, Aline, 18282

Makkonen, Katri M., 18270

Marcellin, Esteban, 18007

Marciniak, Stefan J., 18202

Marobbio, Carlo M. T.,18152

Martens, Eric C., 18445

Martin, Scott E., 18085

Maruyama, Yukie, 18059

Mason, Aaron C., 18458

Masoudi, Raheleh, 18424

Mathew, Smita, 18545

Matsuda, Hiroki, 18545

McDonald, W. Hayes,18434

McGuinness, Owen P.,18368

McLeod, Cameron W.,18377

McManus, Michael T.,18515

Meester-Smoor, Magda A.,18174

Meng, X. Wei, 18311

Menon, Binuraj R. K., 18160

Miaczynska, Marta, 18115

Michelazzi, Silvia, 18167

Mikami, Bunzo, 18059

Miranda, Elena, 18202

Mizushima, Tohru, 18493

Mo, Yin-Yuan, 18515

Mochin-Peters, Maria,17947

Montalbano, JoAnne,18129

Moore, Meika C., 18174

Morris, Kaley, 18401

Muramatsu, Takashi,18411

Murata, Kousaku, 18059

N

Nakamichi, Yusuke, 18059

Nakaya, Tadashi, 18493

Namba, Takushi, 18493

Narumiya, Shuh, 18493

Navab, Mohamad, 18292

Neet, Kenneth E., 18424

Nielsen, Lars Keld, 18007

Nishimura, Susumu, 18218

O

Olchowik, Marta, 18115

Oppert, Brenda, 18401

Oppert, Cris, 18401

Osawa, Rika, 18015

P

Pagadala, Promila, 18424

Pal, Mintu, 18047

Palmieri, Ferdinando,18152

Pan, Yu-Jiao, 17975

Paradies, Eleonora, 18152

Park, Eunsook, 18021

Pasonen-Seppanen,Sanna, 18270

The Journal of Biological Chemistry

AUTHOR INDEX

JULY 3, 2009 • VOLUME 284 • NUMBER 27 JOURNAL OF BIOLOGICAL CHEMISTRY xi

Passaniti, Antonino, 17947

Persichetti, Francesca,18167

Pilecka, Iwona, 18115

Pleass, Richard J., 17968

Pommier, Yves, 18085

Poole, Robert K.,18377

Powlesland, Alex S., 18537

Pratt, Ashley J., 17897

Prindle, Marc J., 18078

Puschmann, Horst,17926

Puts, Catheleyne F., 17956

Q

Qamar, Imteyaz, 18021

Qiu, Feng, 18143

R

Rashid, Sajid, 18115

Reddy, Srinivasa T., 18292

Regan, Andrew D., 17914

Reich, Norbert O., 18390

Renoud, Keli J., 17947

Reyes-Cruz, Guadalupe,18334

Ribet, Carole, 18282

Rodriguez, Anne-Marie,18282

Roth, Robyn, 18445

Roussel, Benoit D., 18202

Rubenstein, Peter A.,18260

Ryden, Mikael, 18282

S

Salib, Maryann M., 17947

Santa-Maria, Ismael, 18218

Sava, Irina G., 18194

Scarpellini, Alessandra,18411

Scemes, Eliana, 18143

Schlieper, Daniel, 18228

Schneider, Paula A., 18311

Scrutton, Nigel S., 18160

Shapiro, Paul, 17947

Sheikh, M. Saeed, 18129

Shemyakin, Igor G., 17902

Shi, Yun-Bo, 18545

Silverman, William R.,18143

Smith, Kimberly K., 18033

Sommers, Joshua A.,18458

Srivastava, Om P., 18481

Steel, Patrick G., 17926

Stenson, Britta M., 18282

Stokes, Sarah L., 18377

Stone, Michael P., 18434

Subramanya, Arohan R.,18471

Sugimoto, Yukihiko, 18493

Suhasini, Avvaru N., 18458

Sun, Chin-Hung, 17975

Sun, Xiaodong, 18184

Suzuki, Toshiharu, 18493

Sy, Shirley M.-H., 18302

T

Takehara, Masaya, 18493

Tam, Fong U., 18047

Tammi, Markku I., 18270

Tan, Chek Kun, 18047

Tan, Ming Jie, 18047

Tan, Nguan Soon, 18047

Tang, Mark Boon Yang,18047

Tan, Siew Hwey, 18047

Taylor, Maureen E., 18537

Teng, Lisong, 18236

Teo, Jamie Wei Ting, 18047

Theilacker, Christian, 18194

Todisco, Simona, 18152

Toma, Ioana, 18194

Torronen, Kari, 18270

Torun, Anna, 18115

Traynor, John R., 18357

Trybus, Kathleen M., 18244

U

Ueda, Miki, 18015

V

Vandermey, Myriam,18323

Vazquez-Macías, Aleida,18334

Vazquez-Prado, Jose,18334

Verderio, Elisabetta A. M.,18411

Voehler, Markus W.,18434

Vollmar, Melanie, 18228

Voloshin, Oleg N., 18458

W

Wade, James B., 18471

Walcott, Sam, 18244

Walko, Gernot, 18525

Waltho, Jonathan P., 18160

Walton, Jonathan D.,18070

Wang, Chuangui, 18210

Wang, Guanghu, 18033

Wang, Haiyong, 18236

Wang, Qin, 18357

Warshaw, David M., 18244

Watabe, Shugo, 18015

Watanabe, Junji, 18292

Wei, Zelan, 18323

Welling, Paul A., 18471

Wiche, Gerhard, 18525

Wiczer, Brian M., 18347

Williamson, Patrick, 17956

Winn, Martyn, 18228

Wirtz, Denis, 18252

Wold, Marc S., 18458

Wong, Marc Hai Liang,18047

Wu, Fangting, 18515

Wu, Hua, 18503

Wu, Jiaxue, 18078

Y

Yan, Sheng, 18537

Yan, Ting-dong, 18503

Yang, Zheqiong, 18033

Ye, Jianping, 18368

Yeatman, Timothy, 18210

Yin, Jun, 18368

Yoon, A.-Rum, 17935

Yu, Mi-Young, 17935

Yu, Xiaochun, 18078

Yun, Chae-Ok, 17935

Z

Zakharova, Maria Yu.,17902

Zeng, Jin-zhang, 18503

Zhang, Fuming, 18194

Zhang, Jin, 18368

Zhang, Xiaohong,18210

Zhang, Xiao-kun, 18503

Zhang, Xiaoshan, 18236

Zhang, Xiaoxue, 18174

Zhang, Yong-Wei, 18085

Zhao, Ke-Wen, 18184

Zheng, Xiaofeng, 17998

Zhong, Quan, 18106

Zhou, Hu, 18503

Zhou, Jingming, 18106

Zhu, Yongyou, 18302

Zwarthoff, Ellen C., 18174

xii JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME 284 • NUMBER 27 • JULY 3, 2009