Motor Neuron Disease and Current treatment

Motor Neuron Disease and Current treatment Yosi w. kusuma. SGD B01What is motor neuron disease?Intro:

(Ice Bucket Challenge)

It is ALS Also known as Lou Gehrig disease Amyotrophic Lateral SclerosisIt is a progressive motor diseaseProgress within 1-5 yearsDeath is usually by respiratory paralysis (What We Know)Epidemiology

Men are twice as likely to be effected1-3 per 100.000 incidenceAnd a high prevalence in the western Pacific region (Guam and Papua New guinea)ALS does not effect the cognitive skillIt only effects the motor skillThe muscle tone become thin and weak

First sign of ALS is developing asymmetric weeks, especially in the distal limbs. And it is asymmetric Then there is difficulty in the facial muscle movement Over time, more and more muscle became involved until the disorder is symmetric and effects all regionsHow do we diagnose?BulbarCervicalThoracicLumbosacralALS is definite if 3 or 4 of the following motor neuron is involved

What cause ALS?mostly it is cause by the defect of the SOD1 gene, that function as a peroxides and antioxidants And for treatment?There is no known treatmentThere is only treatment to lengthen the survivalOnly Riluzole can help patient with ALS

But the spesific mechanism isn't clear yet Some research suggest that the treatment effects the glutamate release concentration of the body What Can We Do?Donate, donate and donateto further research on ALSY.w.k.Every life is a good life.