ALLERGENS IN DETERGENTS AND CLEANING PRODUCTS•Methylchloroisothiazolinone/MCI •Kathon (MCI/MIT)...
Transcript of ALLERGENS IN DETERGENTS AND CLEANING PRODUCTS•Methylchloroisothiazolinone/MCI •Kathon (MCI/MIT)...
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ALLERGENS IN DETERGENTS AND CLEANING PRODUCTSKRISTINA VILE, MSC MOLECULAR BIOMEDICIN
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CONTACT DERMATITIS
ENVIRONMENTAL
MORE CHILDREN
24-48 HOURS
CONCENTRATION
EUROPA: 27 % 18-74 YRS
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POPULATIONS STUDY5 European countries (Sweden, The Netherlands, Germany, Italy and Portugal)
• 12,377 with 32 allergens
• 27 % (18-74 years)
• Women > men
• Allergens• Nickel (14.5 %)• Cobalt (2.2 %)• Fragrance mix I (1.9 %)• Fragrance mix II (1.9 %)• Chloratranol (1.8 %) oak moss & tree moss
extract• HICC (1.4 %) ban (2021)• PPD: (1.0 %)
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MAJOR CAUSES OF CONTACT DERMATITIS/SKIN ALLERGY
• Metals (nickel, chrome)
• Preservatives (MI)
• Perfume
• Coloring (metals, p-phenylenediamine)
• Plants
• Rubber
• Glue
• Sunscreen
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ALLERGENS IN DETERGENTS AND CLEANING PRODUCTS
Allergens
• Perfume• Preservatives• Airborne (MI and formaldehyde)
Irritation
• Surfactants e.g. sodium lauryl sulfate
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PRESERVATIVES KNOWN TO CAUSE ALLERGI
• Methylisothiazolinone/MI
• Methylchloroisothiazolinone/MCI
• Kathon (MCI/MIT)
• Formaldehyde and -doners• Benzylhemiformal
• 2-bromo-2-nitropropane-1,3-diol
• 5-bromo-5-nitro-1,3-dioxane
• Diazolidinyl urea
• DMDM hydantoin
• Formaldehyd
• Imidiazolidinyl urea
• Methenamine
• Paraformaldehyd
• Sodium hydroxymethylglycinate
• Quaternium-15
MORE THAN 6 % IN
EUROPE
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PERFUME ALLERGY – THE 26Regulation 26 perfumes must be declared with names on cosmetic products
0.001 % leave on, 0.01 % rinse off
• Alpha isomethyl Ionone
• Amyl cinnamal
• Amylcinnamyl alcohol
• Anisyl alcohol
• Benzyl alcohol
• Benzyl benzoate
• Benzyl cinnamat
• Benzyl salicylat
• Butylphenyl methylpropional
• Cinnamal
• Cinnamyl alcohol
• Citral
• Citronellol
• Coumarin
• Limonene
• Eugenol
• Evernia prunastri
• Evernia Furfuracea
• Farnesol
• Geraniol
• Hexyl cinnamal
• Hydroxycitronellal
• Hydroxyisohexyl 3-cyclohexene carboxaldehyde
• Isoeugenol
• Linalool
• Methyl 2-octynoate
19 organic
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ARE THE TESTS GOOD ENOUGH?IS THE NUMBERS MUCH HIGHER..?
82 Skin sensitizingperfumes
26 allergens
FM I: 8
FM II: 6
• Most potent allergens of the 26 perfumes - not in test mix
• Patch test with 26 perfumes canidentify 40 % more.
Temamøde Miljøstyrelsen/Sundhedsstyrelsen 4.april 2016 oplæg v. Niels Højsager Bennike.
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DETERGENT REGULATION (EU)
• No rule about full declaration (as for cosmetics)• Contact information to find full declaration
• Use and dosage information
• Preservation, enzymes, disinfectants, optical white and perfume need to be declared
• The 26 perfumes on EU’s list of most allergenic need to be declared with name
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REGULATION – TRENDS FROM COSMETICS
• New EU regulation on claims on cosmetics• Not allowed to write “free from” (e.g. parabens, hormone disrupters, triclosan)• Restrictions on hypoallergenic (misleading)• Not allowed to demean ingredients which are legal and approved for cosmetics
• We believe that this focus will spread to detergents and cleaning products
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EXAMPLES – TRENDS FROM COSMETICS
• Methyldibromglutaronitril (MG)• Regulation for cosmetics – banned in leave-on in 2005• Regulation for detergents and cleaning – banned in rinse-off in 2007
• Methylisothiazolinone (MI)• Regulation for cosmetics – Banned in leave-on in 2016• Regulation for detergents and cleaning – 15 PPM in rinse-off in 2019
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EXAMPLES – HYPOALLERGENIC MISLEADING?
Water, Sodium Coco Sulfate(plant-powered surfactant), Cocamidopropylamine Oxide(plant-powered surfactant), Lauramine Oxide (plant-poweredsurfactant), Coco Betaine (plant-powered surfactant), Phenoxyethanol (preservative), Ethylhexylglycerin (preservative), Tetrasodium Glutamate Diacetate(plant-powered water softener), Natural Fragrance, Citric Acid(plant-powered pH adjuster), Limonene (essential oilcomponent), Citral (essential oilcomponent
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THE FUTURE
• Full declaration on detergents and cleaning products
• Focus on claims – cosmetics regulation as a precursor
• Higher focus on skin friendly and not only natural
• Think skin friendly in development of products
• Be prepared by getting knowledge about the cosmetic products
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Claims:Free from
What has been used instead?Dermatological tested
On how many, what were the result?Hypoallergenic
Means less, but less than what? Free from parabens
Hypoallergenic
Hypoallergenic
WHY CERTIFICATIONS?Many misleading claims on products
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TERMS AND REQUIREMENTS FOR THE PRODUCERS
Prohibitedchemical/ classified
RecipeMSDS safetyassessment
New criteriaTDS raw
materialsSample test
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FACTS• AllergyCertified launched in February
2015
• >850 certified products
• International
• Health label
• Allergy
• Endocrine disrupting chemicals
• Carcinogen
• Raw materials
• Advisory board
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HOW TO USE ALLERGYCERTIFIED?
• Follow us on Facebook or LinkedIn https://www.facebook.com/allergycertified/https://www.linkedin.com/company/allergycertified
• See our website on chemical of the month http://allergycertified.com/blog/chemical-month-cocamidopropyl-betaine/
• Sodium Laureth Sulfate as chemical of the month http://allergycertified.com/blog/chemical-month-sodium-laureth-sulfate-sodium-lauryl-sulfate/
• Write us if you have any questions about allergy