AGROPROCESSING AND NATURAL PRODUCTS DIVISION

CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST) Thiruvananthapuram,

Microbiologist

Chemists

Biologists

Industry/

The Team ……..

Food Technologists

Chemical Engineers

 Flavour Science & Technology (Spices)

 Lipid Science & Technology (Oilseeds)

 Natural Products (Herbs)- A Chemistry/ Biology/ Chemical Engineering Interdisciplinary programme

Vision

“ To emerge the first choice of the users of its outputs of R & D, be it technology, product, service or knowledge”.

Analytical facilities (In-house)

GCMS

HPLC

HPTLC

Confocal Microscope

Flow Cytometer

Real time PCR

Multimode readers

FTIR

 Particle size analyser

Texture analycer

Freeze drier/ Lyophiliser

Polarimeter

Colorimeter

Differential canning

colorimeter

Oil seeds/ Flavour Science & Technology Group

7

Services rendered by the Oil seeds/ Spices group

• Process Development

• Technology transfer/ Industrial trouble shooting

• Scale up processes at Pilot Plant

• Preparation of DPR

• Detailed engineering of the plant

• Engineering support for erection and commissioning of the plant

• Training of operating personnel

• ost commissioning assistance and product analysis.

Concept to CommercializationConcept to Commercialization

FRESH GINGER PROCESSING TECHNOLOGY IN NORTH EAST

• NIIST have set up commercial ventures in North East states of Manipur, Meghalaya, Sikkim for processing of Ginger, Turmeric and Green Cardamom

• Technology transfered to Mizoram & Arunachal Pradesh to set up commercial units

• Ensured remunerative return to the rural farmers

A New Venture to cater 7.5 TPD ginger is under implementation at Wayanad, Kerala

Current status

Pre Commissioning trials over

TURN KEY EXECUTION FRESH CHILLI PROCESSING UNIT AT BYADAGI

• First venture in India for Processing of 20 TPD of Fresh Chillies making High Colour value added product free of Aflatoxins

• Continuous processing which can cater chilli right from harvest even during adverse conditions

• Employment for 20 rural unskilled women and Remunerative prices for farmers

Science & Technology to the rescue of the Chilli farmer

Concept to commercialization

Refrigeration/Adsorption dehumidified drier

Problem  Drying during the rainy harvesting

season  Very long residence time for drying  Development of surface cracks on

dried products  Loss of essential oils  Oozing out of essential oils on

dried product

Result  Operate at lower temperature and

shorter drying time  Higher mass transfer rate  Improved product quality  Catapulted one entrepreneur as

the largest exporter of Nutmeg from India

Solution Energy efficient refrigeration/adsorption dehumidified drier designed and commissioned Capacity: 2T/day

Processing of Nutmeg prior to 2011: (Counter Clockwise from Top): 1. Sun Drying of Nutmeg; 2. Firing of Hot Air Generator 3. Mat over which Nutmeg is spread for drying; 4. Drying in Progress

Processing of Nutmeg under New System: (Clockwise from Top): 1. Nutmeg readied to be loaded into Drier; 2. Nutmeg being stacked in the Insulated Drier Room; 3. The RADD System

Aflatoxin free products for Exports to New Markets: Europe and USA

Manual sorting to remove un-dried nutmeg; 2. Firing of the Hot Air Generator

Modernized Unit has vastly improved the Quality of Work and Life of Workers

NIISTTBIC

Technical Support

Equipment Lease

Start-up Companies

Funding agency

Grant for basic infrastructure

Venture finance

Exit Ventures

“Sweat Equity”

Return on “Sweat Equity”

A specialized facility where essential infrastructure, technical expertise and consultancy services are available

TBIC IN AGRO PROCESSING

A JOINT INITIATIVE OF CSIR – NIIST & GOVT OF KERALA

Entrepreneurs

Natural Products (Auyrveda)

Chemistry/ Biology/ Chemical Engineering Interdisciplinary programme

EXTRACTS CHEMICAL

ANTIOXIDANT ACTIVITY

BIOLOGICAL

ACTIVITY

PRODUCTS: FUNCTIONAL FOODS NUTRACEUTICALS

EVIDENCE BASED HERBAL/NUTARCEUTICAL PRODUCTS FOR PREVENTIVE HEALTH AND DISEASE MANAGEMENT

Products Focus

Herbal pills/soft gel capsules/supplements Bioactive phytochemicals for health management

Health food suppliments: Prevention and management Diabetes, CVD

Instant drinks Microencapsulated ready to reconstitutable drinks with antioxidant, immune health and general well being bioactives

Functional vegetable oil With antioxidant, disease preventive and general well being bioactives

Functional Shortening Tailor made shortenings with antioxidant, cholesterol lowering, health management bioactives

Biology programmes in AP & NP Division

General Objectives Development of nutraceuticals for general well being and preventive

health Lead generation from medicinal plants (Ayurveda, traditional

knowledge- documented and non-documented) for diabetes,cancer and cardiovascular disease (CVD) Bioprospection of Western Ghats biodiversity for sustainable use Development of new screening models & biomarker for Diabetes,

CVD & Cancer

Fractionation

Active fractions

Detailed activity studies- antidiabetic, antiinflammatory, anti cancer & against CVD

Antidiabetic studiesAntidiabetic studies

Anti inflammatory studies

Anti inflammatory studies

Insulin secretion Glucose uptake

Cell differentiation Inflammatory

cytokines NFkB expression

Insulin secretion Glucose uptake

Cell differentiation Inflammatory

cytokines NFkB expression

Anti oxidant studies- Chemical & cellular

assays

Anti oxidant studies- Chemical & cellular

assays

Active extract

Sequential extraction

Anti oxidant studies Chemical assays

Anti oxidant studies Chemical assays

CVDCVD

Extraction of bioactives and evaluation of biological activity

OXIDATIVE STRESS DIABETES INFLAMMATION CVD CANCER

Free radicals α-amylaseinhibitor COX inhibition In vitro LDL

oxidation MTT

GSH & GSSG α-glucosidaseinhibitor Interleukin secretion ACE inhibitor

Cell cycle assay

GPx/GR Glucose uptake NFκB expression HMGCoA reductase inhibition

Apoptosis

SOD Glut4

expression/ translocation

COX expression Angiogenesis

Catalase Adipocytedifferentiation

Models for biological evaluation

 Product quality and stability studies

 Process development in lab level

 Scale up studies in pilot plant

 Cost evaluation and feasibility studies

 Product supply for test marketing

Product formulation and process development

To sum up ……To sum up ……

Convergence of expertise in Engineering/Food technology/ Biological areas to add value to regional resources

Enzyme assisted processes for active ingredient isolation Marketing of Generic expertise Solvent extraction, drying, oil seeds & spices processing - Engineering new Industrial ventures

Modernization of the traditional Ayurveda sector/ functional , nutraceutical food industry

Continue to offer technological support to oil seed / spice industry

 Creating the environment and opportunities for new venture creation in Agro processing through TBIC by

Market research and preparation of business plans for venture funding ,Technical co-ordination with statutory agencies, financial institutions and prospective end markets  Nucleating and accelerating collaborative technology projects suitable for new venture development through TBIC

THANKS