Aging Matters Issue 4, 2012
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Transcript of Aging Matters Issue 4, 2012
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3Welcome What a delight it is for me to welcome back one of the worlds most remarkable antiaging physicians - Dr. Ward Dean. Its a double whammy for us, since hes discussing his specialist subject of smart drugs and nutrients. These are substances which have been shown to improve learning, memory, attention, focus and even intelligence- and not only in individuals who are suffering from known problems- but even individuals who are considered to be normal and why not? After all, the purist form of antiaging medicine is not to just be content with normal, but to strive for optimal. Many of you might have Dr. Deans smart drugs and nutrient books from the 1980s; they were best sellers in their class, so its great to have an update from him here in this Aging Matters magazine.
Plus we have the free radical expert Dr. Richard Lippman discussing how to eradi-cate and reduce the bodys production of unhealthy free radicals. His work was nominated for the Nobel Prize in medicine, so its worth taking notice of!
And Britains top antiaging physician, Dr. Marios Kyriazis updates us on Can-C, the remarkable original, clinically proven anti-cataract eye-drops; unbelievably its been 10-years since they first appeared.
This issue is all about what more we know now that we didnt know then!
Phil Micans, MS, PharmBEditor, Aging Matters Magazine
Declaration: The IAS Aging Matters magazine focuses on the latest international nutritional, hormonal and drug therapies to help combat the signs of aging. These signs include the physical, mental and internal changes consisting of the diseases and disor-ders such as cancer, arthritis and senile dementias etc. However, the main focus is upon the prevention of such aging diseases and disorders for the healthy-aging individual.
Copyright 2012: All copyrights are acknowledged. Whilst every effort has been made to ensure accuracy, no responsibility can be accepted for illustrations, photographs, artwork or advertising ma-terials while in transmission or with the publisher or their agents.
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IndexWelcome -Phil says thanks for finding the time
Smart drugs and nutrients -Our lead story from Dr. Dean Beating free radicals -Dr. Lippman tells us how Can-C eye-drops 10-years on -What do we know now? Featured products
New to IAS
Product A-Z list and prices
Condition cross-reference list -find the right product for you
Contact details & FAQs -all our details are here
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Smart drugs and nutrients - an interview with Ward Dean, M.D.
and cognition. Were you surprised at the response you received?
Dr. Dean: First, youre correct that the books were, in essence, technical manuals. I wrote them for my patients, to save my time and theirs, in explaining various cognitive-enhancing drugs and nutrients that I was recommending for them. Although I initially planned a press run of about 500 copies, John Morgenthaler, my co-author and publisher had grander visions. As a result of his creative publicity and marketing skills, the books sold in excess of 250,000 copies each. We had obviously hit a sensitive nerve; we discovered that there was a large number of people out there-more than just my patients- who were concerned about their cognitive processes and memory. These were people of all ages, most of whom werent suffering from a senile dementia--they just werent as sharp as knew they could and should be-or had formerly been-and therefore received no advice or treatment. By publicizing the available cognitive enhancing drugs and nutrients, and explaining their mechanisms of action, dosages, and sources, weve been able to help people who were clinically cognitively impaired, as well as those who were considered to be normal. The appropriate use of an assortment of various cognitive enhancing drugs and nutrients has improved the memory of many people, and taken them to new levels of alertness, cognition, attention and focus. Its been very gratifying to hear stories of those whose lives were completely turned around with the use of these nutrients and drugs. And at the same time, I wonder if the producers of the movie Limitless werent among the readers of my books!
Phil: At the time your books came out, you highlighted a number of substances that were available in Europe, such as piracetam and centrophenoxine, but that were not available in the States. Has anything changed since then and if not why not?
Dr. Dean: Some things have changed. For example, when the books came out, DHEA was available only by prescription through compounding pharmacies; Acetyl-L-Carnitine was available as a drug in Europe (especially, Italy), but nowhere in the U.S.; Vinpocetine was only available as a drug in Hungary; and Idebenone was an expensive pharmaceutical drug available only in Japan by prescription. Of course, all of these formerly exotic cognitive enhancers are now available over the counter as dietary supplements in the U.S. However, drugs like Lucidril (centrophenoxine), and piracetam and related nootropics are still not marketed in the U.S., although they are widely used in Europe and Asia. Unfortunately, as the patent protection on these drugs has expired, no pharmaceutical company will now pursue them for approval in the U.S.
Phil: So, does that mean there are newer and better drugs now available on the US market?
Dr. Dean: Not really! There are several relatively new drugs that may offer potential benefit for Alzheimers patients that are now available in the U.S. One is Radazyne (U.S.), Reminyl (Europe). Its generic name is galantamine, an extract of the snowdrop herb, which acts as a reversible acetylcholinesterase inhibitor. Another anti-Alzheimer drug is Namenda (U.S.),
Phil Micans interviews Dr. Ward Dean, who is perhaps best known to the public for his two best-selling books on Smart Drugs & Nutrients (versions I and II) in the early 1990s. Dr. Dean graduated from the US Military Academy at West Point in 1967, and served in the Infantry for six years, posted to both Airborne and Ranger forces. He obtained his medical degree from Han Yang University in Korea in 1978, and returned to the Army as a Flight Surgeon for the elite Delta Force from 1982-1985. Dr. Dean later transferred to the Navy, from which he retired as a Commander, in 1996.
Dr. Dean is one of the foremost physicians in antiaging medicine today. He is a true pioneer of the movement and an expert in biomarkers, having published what is still considered the Magnum Opus on the subject--Biological Aging Measurement--Clinical Applications, published in 1988. Dr. Dean is also responsible for bringing the Neuroendocrine Theory of Aging to the attention of the world, having co-authored its release with Professor Vladimir Dilman in 1992. He has recently returned to his former position as Medical Director for the Watson Clinic, in Milton, Florida.
Here in this interview, Phil asks Dr. Dean about his current opinion about nootropics and their role in aging.
Phil: Dr. Dean, its a great pleasure to be able to talk with you today. Im sure Im only one of many people who have missed your presence on the scene for the past six and one half years, while you endured the hospitality of a federally-funded, secure gated community. If I may, Id like to chat about one of your favorite topics-the nootropics, or the so-called smart drugs. Unbelievably, your two best-selling books are 20 years